The treatment method polyesterwith

 

(57) Abstract:

The invention relates to medicine, arthrology and can be used for the treatment of polyesterwith. Spend amplipulse 5%-aqueous solution of Epsilon-aminocaproic acid locally on two of the most affected joint. Previously by amplipulse therapy effect to the corresponding segmental spine. The first two treatments a day, and then daily for the overall hydrogen sulfide baths. Course 7 balneo - and 10 physical therapy after a period of adaptation. The method allows to increase the effectiveness of treatment of polyesterwith. 6 table.

The invention relates to medicine, namely to arthrology, and can be used in medical practice for the treatment of patients with poliosteoartroz.

There is a method of treatment of osteoarthritis by applying hydrogen sulfide baths, with a gradual increase in the concentration of hydrogen sulfide (Tsarfis P., Nature and man. - M., 1980, - S. 275).

However, the application of known methods gives a pronounced positive clinical effect only in 53% of cases.

Known application amplipulse therapy on local methods for diseases of the joints - perifericheskie antiirus effect of balneotherapy, is a local physical effects, in particular electrotherapy sinusoidal modulated currents on segmental-local methods with simultaneous foretical the introduction of medicinal substances directional - 5% solution of Epsilon-aminocaproic acid (AACC to the area most affected joints.

Object of the invention is the reduction of treatment time and the exception paleopathological reaction.

The solution is achieved by the fact that after a period of adaptation to the background of mos balneotherapy in patients with poliosteoartroz designate amplipulse therapy on segmental-local methods with simultaneous amplipulse 5% solution EACH on two of the most affected joint is the first 2 procedures a day, and then daily.

The method is as follows: the method is performed by using an apparatus of low frequency physiotherapy "Amplipulse-5" and set the standard plate of lead electrodes and the corresponding hydrophilic gauze pads. Vacation procedure occurs in two stages:

- the first stage - the impact on the corresponding reflex-segmental paravertebral area (PR the electrodes 4+12 cm is placed paravertebral - one left, the other right. Mode, range, duration parcels, type of operation, the frequency and depth of modulation. the exposure time is shown in table 1.1 and 1.2. Current is set at the level at which the patient feels pronounced painless vibration;

the second stage will have a local impact on the most affected joints with simultaneous amplipulse 5% solution EACH. The standard plate electrodes 4+8 cm impose on no more than two of the most affected joint with gaskets, pre-moistened with a solution EACH (0.5 ml of 5% solution EACH in 20 ml of physiological solution). Parameters vacation procedures are listed in table 2.

Table 3 also explains the proposed method.

The prevalence of diseases of musculoskeletal system (up 42%) determines the relevance of search methods and means of pathogenetic therapy, primarily non-drug. From 40% to 80% of the working age population aged 25-55 years suffer multiple degenerative diseases of joints.

Accompanying osteoarthritis, osteochondrosis of the spine is often accompanied by autonomic disorders with impaired accessories which are effective pulse currents of low frequency, in particular sinusoidal modulated currents. The latter stimulates peripheral circulation, improve the functional state of the neuromuscular system, have parasympathicotonia action. Expanding the scope of coverage of the affected joints allows segmental-local technique amplipulse therapy. Promising to increase the effectiveness of physical therapy while phoresis drugs directed action. Selection of drug - EACH due to several of its properties: antifermentny activity, decrease vascular permeability, immunosuppressive effect.

A specific example of the method.

Patient E. , 40 years, in the last 5 years, suffering from poliosteoartroz, buzzella form, with a primary lesion of the knee, II stage, FTS I senior Companion: osteochondrosis of the lumbar spine, lumbodynia. Treated regularly as an outpatient, you should cancel frequent reactive synovitis, especially after exercise, reduced intake of nonspecific anti-inflammatory drugs.

The patient was prescribed a course of treatment by the proposed method.

Portability Provo is of lumbodynia after 2-3 procedures amplipulse therapy, and arthralgia after 5 treatments. The patient became more active, increased range of motion in the knee joints and the lumbar spine. Clinical improvement was accompanied by positive changes in laboratory parameters: complete blood count remained within the normal range, was neutralized monocytosis (from 12% to 7%). Picture of white blood indicated the transition defective reaction increased activation in response to "calm" activation. Anti-inflammatory effect of the treatment was confirmed by the decrease in the level of fibrinogen with 3.75 g/l up to 2.06 g/l, acid mucopolysaccharides with 0,280 g/l to 0,158 g/l As an inhibitor of proteolytic enzymes, EACH showed their trophic effect is normalized to the end of treatment, the number of medium molecular peptides with 0,368 srvc. units to 0,230 srvc. units of the Latter undoubtedly was a result of improved peripheral circulation under the influence of pulsed currents (with reflex and local areas), which was confirmed by the results rheovasography of vessels of lower extremities. Analysis of fibrinolytic activity of plasma did not reveal her oppression by a tendency to increase the FAP with 189,6 to 216,1 minutes 06 immunomodulating action is evidenced by normalization of immune status of the AI in the direction of helper cells.

At the end of treatment the patient was discharged with "significant improvement".

The proposed method of treatment in 25 patients poliosteoartroz, stage I-II, FTS I tbsp. associated with osteochondrosis of the spine with moderate pain (12 women and 13 men aged from 32 to 56 years). Disease duration was on average 4.2 years. On the background of the main medical complex (gently-training regime of physical activity, morning and therapeutic exercises, climateprotection 1 with the transition to 2 modes, mos balneotherapy on shortened methodology to 7 baths on the course) of patients 1 (prototype) group 30 people received mos therapy according to the standard technique In 25 people tested 2nd group major medical complex was reinforced amplipulse therapy on segmental-local methods with simultaneous gel 5% solution EACH on two of the most affected joint.

The effectiveness of the treatment was assessed by the dynamics of clinical data, the degree of arthralgia and its structure is based on questionnaires (questionnaire Mac-Gila modification centuries Kuzmenko, 1986). The state of the peripheral circulation was determined by the results of the days of the limbs. , what about which determined the activity of the inflammatory process in the joints. Status of connective tissue metabolism to be judged by the content of medium-sized molecules and the number of sulfhydryl groups. The last level of catalase blood characterized and the own activity of the antioxidant system of the human body. The immune status was assessed by standard immunological blood of the patient. The state of protective-adaptive forces of the body reflected the expanded formula of white blood and its evaluation by the Christ-Quaking.

Analysis of therapeutic efficacy study of resort complexes in a sufficient therapeutic effect of sanatorium rehabilitation visitors (on average 90% of the clinical laboratory "improvements") revealed an increase in average 7-8% in combination with amplipulse solution EACH on the area affected joints while reducing paleopathological reactions in 5.3% of patients. Results clinical and laboratory studies have clarified the mechanisms of therapeutic action of the studied medical factors. Additional inclusion in integrated mos balneotherapy of amplipulse solution EACH on the affected joints provided more pronounced than in the checkpoints for important locations is eroticheskoe actions inhibition of the processes of proteolysis. By the end of treatment in patients in 20% of cases of "defective" adaptation reactions were transformed into "full", the number of reactions "training" increased from 20% to 25%. Anti-inflammatory effect of therapeutic complex in addition to a significant reduction of pain (according to the questionnaire pain) confirmed a significant decrease in the content of acid mucopolysaccharides with has 0.168+0.003 g/l to 0,149+0.20 g/HP Celebrate the sick by the end of the course of treatment reduced sense of coldness of extremities, numbness accompanied by positive dynamics of indicators of peripheral blood: the peak amplitude of rheovazogram acquired a rounded shape, increased eographically index of 1.46+0.11 to 1,90+0,17, P<0,05. Trophic effect of comprehensive rehabilitation braking processes of proteolysis was accompanied by a significant decrease in the level of medium-sized molecules with 0,311+0,011% to 0,277+0,005%, P<0.05 and the stimulation of its own antioxidant activity: the increase of catalase activity from 20.5+3,6 MK kat/l to 28.5+3,2 MK kat/l, P<0,05. Given the pharmacological ability EACH to the inhibition of fibrinolysis treatment in the 2nd group was carried out under the control of the fibrinolytic activity of plasma (FAP). Although the original was cialis with 198,60+7,10 to 216,15+6,26 minutes This fact confirms the need for careful selection of patients, taking into account contraindications to the drug. About reducing autoimmune shifts evidenced by normalization of the number of T-lymphocytes from 16.2+2,0% to 12.6+1,76%, and, as a consequence, the normalization of the level of immunoglobulin And from 4.29 to+0.30% to 2.83+0,46% and class M 2,44+0.21% to 1,88+0,46%.

Thus, in cases of multiple degenerative joints, including joints of the spine, at all stages, particularly in the presence of reactive synovitis recurrent nature, has often autoimmune Genesis, the purpose of the complex Spa treatment including a shortened course mos balneotherapy and reflex-local methods amplipulse therapy with simultaneous amplipulse solution EACH on the most affected joints provides increased therapeutic efficacy resort rehabilitation of patients by an average of 7-8% in shortened up to 16-17 days with a significant reduction in the number of cases paleopathological reaction (table 4, 5).

From table 5 it is seen that the proposed method % reduction in defective reactions in 4 times more than the prototype (-20,0% against -5,0%). In the CE greater.

The treatment method polyesterwith by mos balneotherapy held through the day, and the impact of physical factor sinusoidal modulated currents from device "Amplipulse-5" by the local method, characterized in that after an adaptation period of conduct amplipulse 5%-aqueous solution of Epsilon-aminocaproic acid locally on two of the most affected joint with a preliminary impact amplipulse therapy to the corresponding segmental spine, the first two treatments a day, and then daily for the overall hydrogen sulfide baths on course 7 balneo - and 10 physical therapy.

 

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FIELD: medical engineering.

SUBSTANCE: device has container for keeping product to be applied, dosing unit for distributing the product, power supply element placed near the dosing unit. The dosing unit is designed as rotating element and is apiece of felt. Container walls are flexible. The dosing unit is manufactured from electric conducting material and connected to the power supply element.

EFFECT: enhanced effectiveness in carrying out viscous product iontophoresis.

8 cl, 7 dwg

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