A method of treating an unquenchable pain syndrome arthritisarthritis knee
(57) Abstract:The invention relates to medicine, therapy, can be used to treat an unquenchable pain syndrome arthritisarthritis the knee joint. Identify dominant painful lesions in the lumbosacral level and enter periradicular 3-6 ml of Nervina Kozyrev Century A. who prepared immediately before administration by mixing 10 ml of 2% solution of novocaine, 1.0 ml of 0.02% solution of vitamin b 12, 1.0 ml of 2.5% aqueous suspension of hydrocortisone, 1.0 ml of 2% solution of papaverine hydrochloride, with painful lesions docked in series in one day. This invention leads to relapse-free recovery. 3 C.p. f-crystals. The existing division of diseases of the knee joint inflammatory conditions (arthritis and degenerative-dystrophic diseases (arthrosis) - conditional, because they have a common etiopathogenesis and common pathogenetic treatment. In fact, this is essentially the successive stages of a single, progressive pathological process arthritisarthritis, i.e. the initial and final stage functional and morfometricheskoi destruction of the knee joint as a result of his denervation.Further, in the description matalina problem orthopedics, having not only medical, but also social value. A very common disease of middle and older age. Not rare in children of school age.According to published data, among the musculoskeletal structures of the knee joint takes the second place.The invention relates to medicine and can be used in orthopedics and traumatology, neurology and neurosurgery outpatient, conservative treatment of patients with unquenchable pain syndrome arthritisarthritis knee joint (Juices L. P. Romanov, M. F. Deforming arthritis of large joints. - M.: Publishing house of peoples ' friendship University, 1991, 118 S.).This work can be considered as a prototype.Clinical development and course of disease arthritisarthritis begins from afar. The patient appear lumbosacral pain, usually on the left, coming, of various intensities. Can radiate to the left leg, most often in the morning, and disappear during the day. Over the years the intensity of pain, occasionally appear in the left knee joint. The patient begins treatment with a neurologist about lumbago, isoreticular, radiculopathy pain center becomes the left knee, on the side of the source of intoxication, and lumbosacral pain does not disappear, and leave the field of view of the patient and neurologist.Pain in the joint is tense at times, with time increasing in intensity and permanence. They mainly occur at the beginning of the walk, i.e., the morning of the start of pain, worse after exercise. There is no alone. On the background of the remission of joint pain begin to remind yourself of pain in the lumbar-sacral area.Over the years, joint pain grows up unquenchable, depletes the patient mentally and physically, leading him to suicidal thoughts and attempts to implement them.The knee becomes dominant in the extinction of active and passive functions, neurodystrophic, neurodestructive its tissue structures.Palpation is defined soreness in the joints and periarticular tissues.The emergence of joint pain usually associated with stretching of the joint capsule, intra-articular entrapment of the "mouse", friction naked epiphyses and mn. otherRadiographically detected narrowing of the joint space, subchondral sclerosis, marginal bone growth, osteoporotic changes in the adjacent sostavlennyh radiographic changes in the joints allow neurologist and orthopedist for the patient with osteoarthritis of the knee joint in a hospital.For the treatment of arthritis developed various therapeutic complexes with the use of multiple therapeutic agents and methods. Ineffective treatment of arthritisarthritis knee joint in many ways is their validity to the pathogenesis at the level of assumptions. This confirms the absence of recovered patients.Long-term drug treatment increases the severity of the disease, because increasing the concentration of toxins in the blood drug intoxication and thereby increases toxic damage sensitive roots of the spinal cord L3- L4-S1- S. in fact and essentially compounded by the denervation of the knee - their areas of innervation. Closes a vicious circle with all the ensuing consequences, leading to functional and structural destruction of the knee joint.Indications for General use surgical methods of treatment of arthritisarthritis of the knee joint are often long ineffective conservative treatment, the growth of articular pain syndrome to insatiable, loss of its function, progressive neurodystrophic and tissue destructive processes.Currently there is no common view on the cause of the disease and death of the knee joint, despite the progressive improvement of diagnostic methods. As a rule, numerous causal factors are divided in primary and secondary. Moreover, the question of the true pathogenesis of arthritisarthritis knee remain unrevealed.Even though in orthopedics emerged and became widespread in new direction, neuroactive - unquenchable pain when architekturze is assessed as totally subjective feeling of the patient on the background of heavy, hopeless to cure diseases, and to the etiopathogenesis of the past is not relevant. Pain and artresources different, separate disease. They have different flow and different treated long-term, persistent and not now.A natural question arises: why in the presence of infinitely diverse conservative and surgical treatment unquenchable pain and neuro-degenerative-dystrophic processes arthritisarthritis Onegina in clinical practice theory of pain Kozyrev C. A., protected by patents of the Russian Federation and does not have analogues in the world.The first premise of theory of pain no doubt is that the only source of pain - struck a sensitive nerve. His abnormal impulses transformed subcortical and cortical structures of the brain in pain. While none of the structural formation of the spinal cord and brain has no ability pathological pain pulsation. The first conducting pain impulses, and the second it transforms in pain.Operations on the brain, spinal cord and heart has been and can be carried out under continuous local Neocaesarea sensitive nerves of the soft tissues in the area of the surgical field. In brain and heart tissues operations are performed without anesthesia for the reason that they do not have sensory nerves that give pain impulses (Author).Healthy sensitive nerve has only sensory function at its innervated area. Therefore, it is a duty "military post" on their Autonomous territory, proactive damage to the body.You touched the fire and instantly took the limb. You stumbled e, he gave the command of motor coordination structures and the body is saved from the heavy defeat and much more.To fulfill its purpose sensitive nerve must possess exceptional property, only it has no any other structural formation of the Central and peripheral nervous systems. This property is congenital, genetic sensitivity to the concentration of toxins which get into the blood.He also endowed with unlimited powers impact on the vascular system at a subconscious level.In this framework he gives emergency, lightning team to action, proactive damage to the body.Sensitive nerve also has trophic tissue impulses. Any denervated tissue, organ perish in their own way and in a certain sequence, including the knee.Today in theoretical and practical medicine denervated processes are defined as degenerative-dystrophic, unknown etiopathogenesis. Consequently, there is no pathogenetic treatment.Example: after mechanical or toxic destroyed the em neurodystrophic and destructive processes, from which the tooth dies, and could stay healthy after one perineurally injection of Nervina Kozyrev Century A. Thus, the dentist consistently cleans the mouth from the teeth.In the same way, but from toxic damage sensitive roots of the spinal cord L3- L4- S1- S2in the area of innervation of the dies from denervation of the knee joint. It is in this particular patient, sensitive roots was the lowest genetic threshold for a given concentration of toxins in the blood.In turn, progressing to an unquenchable pain creates pathological, destructive, functional peace leading to the increasing deficit of the circulation at the macro and micro levels, accumulation of toxins, aseptic inflammation, serial destruction of tissue and primarily cartilage and so on, Ending toxic denervation neurodystrophic process in the knee joint's functional and destructive death.Thus, the exclusive property of each healthy sensory nerve is individual genetic, innate sensitivity to the concentration of toxins which get into the blood (Author).On the nature of the toxins sensitive nerve does not respond. He responds pathological pain impulses only on their threshold concentration in the blood. If the concentration of toxins in the blood subthreshold, nerve calm. When the concentration of toxins at the level of the threshold, the nerve gives pain impulses, only in response to his palpation irritation at the point of its projection. Above-threshold concentration causes continuous pain impulses because the nerve is in a state of severe toxic damage. Clinically it is manifested unquenchable pain in the area of innervation of the nerve in question.Internal foci of chronic viral-infectious inflammation generates only family infection. Each family has its own infection that is passed from generation to generation. The mother passes the infection to the newborn during the first communication with him. The fate of the child's health will be determined by the degree of activity of the organism protection from family infection. Will grow the child carrier of this infection or the victim of it. With the development of the him against the. the system is a carrier of family infection blood circulation to the left, more oxygenated than the right. In the process the lives of all family members remain carriers of the family of viral-bacterial infection. Ill be the one who will arise and progresses with age partial immune deficiency.When developed internal foci of chronic infectious inflammation, the concentration of toxins in the blood is always the maximum on the left-side sources of intoxication. The concentration of toxins is the same at all levels of the circulatory system to the left. Amazed at all the sensitive nerves and their topical group left. The clinical manifestation of the pain of them will give one the only topical group sensitive nerves with the lowest genetic sensitivity to toxins.Penetration of toxins into the blood from the outside in the circulatory system, their concentration is always the same on the right and left. Toxic damage sensory nerves, usually total. Bilateral clinical manifestation of pain will provide the group with the lowest genetic sensitivity to toxins.However, the etiopathogenesis of toxic damage sensitive nerves of different Il CLASS="ptx2">The consciousness of the person captures attention, usually at the most painful point, which exactly corresponds to the projection of sensitive nerve. The latter accepts irritation outer casing, epineurium equally along its entire length. Specific local structures differentially receptive irritation, he does not.If the currently existing dominant pain hearth docked, does not appear immediately, but is dominant painful lesion in the area of innervation of other sensitive nerve with currently the lowest genetic sensitivity to toxins, etc. This dominant pattern requires consistent relief of all dominant painful lesions in the area of innervation of specific sensitive nerve or topical groups. Insatiable pain will stop only after cupping the last dominant pain topical focus group. In this case, it is the rear sensitive nerve roots of the spinal cord lumbosacral level L3- L4- S1-S2only they innerviews the knee.Wave-like intensity unquenchable more what about the process in chronic infectious inflammation - sources of infectious intoxication.When internal and external favorable conditions for infection immediately begins to multiply, it also dramatically increases the concentration of toxins in the blood, exceeding the threshold of sensitivity of the posterior roots of the lumbosacral level, inhibited the activity of the immune system of the body. In the result, respectively dramatically increases the intensity of the pain abnormal pulsation sensitive roots of the spinal cord L3-L4-S1-S2that transforms sensory brain structures in unquenchable pain omission.The patient begins to consume various painkillers, thereby increasing the concentration of drug toxins in the blood. The vicious circle is closed.With the disappearance of optimal conditions for propagation of the infection the process is stabilized down. The intensity of the pain regresses, etc.To the above-threshold spike concentration of toxins in the blood with a sharp increase in pain pulsation sensitive roots of the spinal cord lead and other exogenous and endogenous factors.The first link in the chain of etiopathogenesis of artrite blood circulation to the left, on the side of sources of intoxication family infection. Maximum pain develops at the lumbosacral level L3-l4-S1-S2and in the area of innervation - the left knee joint. For the reason that these sensitive spinal roots and only this topical level and only the patient has the lowest genetic threshold concentration of toxins which get into the blood, as compared with other topical groups sensitive nerves of the head, neck and occipital, breast, etc. that Is the Law of the formation of dominant painful lesions, according to theory of pain Kozyrev Century A.Affected by toxins in the blood are sensitive posterior spinal roots are sources of pathological activity - pain, trophic and vascular, leading to the emergence and progress of arthritisarthritis the knee joint. Its essence - neurodystrophic and destructive processes as a consequence of various degrees of denervation of the knee joint. The latter closes the vicious circle. The decomposition rate of its tissues is directly dependent on the speed of toxic denervation of the knee joint.Conclusion
According to theory of pain the Trump is - the prevention of toxic denervation of the knee joint, and pathogenetic treatment involves reorganization of the sources of intoxication, mild unquenchable pain syndrome, periradicular by injecting the Nervina Kozyrev Century A. at the level of L3- L4- S1- S2and complex, active rehabilitation of the joint.The claimed method is the basic guideline for addressing the prevention and treatment of arthritisarthritis with their neurodystrophic and destructive processes.The claimed method provides pathogenetic, comprehensive, outpatient treatment by addressing the true causes of the disease and its consequences.It guarantees relapse-free recovery of the patient.Thus, the path to prevention and treatment unquenchable suffering opened theory of pain Kozyrev C. A., unequaled in the world and protected by patents of the Russian Federation.The method is as follows - you need to solve four tasks:
1. To identify and repair pockets of chronic infectious inflammation - sources of intoxication.2. To balance the function of the nervous system.3. Dock d is solved only one or two tasks, the patient is healthy never will be. The claimed method requires an integrated, simultaneous solution of all problems.1. Objective examination of the patient revealed foci of chronic infectious inflammation. This is a standard group of foci of family infection, and, as a rule, left-sided localization: adenoids, chronic tonsillitis, gingivitis, sinusitis, chronic otitis media, with progressive hearing loss, urogenital organs, etc.Examine the blood on sterility. Spend the rehabilitation of all foci of chronic inflammation, under the control of crops from them on viral-bacterial flora, with definition of sensitivity to antibiotics, with subsequent targeted antibiotic therapy and follow sowing.2. To normalize the function of the nervous system, individually pick 1-2 medications in character and quality for short-term reception. Targeted therapy saves the patient from fear before resuming unquenchable pain. The activity of the immune defence system of the body malfunction-free increase: regular, metered load, contrast hydrotherapy (exercises vessels) and self-massage roller massage ribbon. In the food rationalism is eternal, continuous struggle in the medical world with an insatiable hunger pain? Two ways:
A. Destructive ways. Their infinitely many. Destroy the source of pain at the dentist is to find and remove sensitive nerve or destroy the poison. The most popular is arsenic. More sophisticated destructive methods used by neurosurgeons and surgeons. The destruction of the source of the pain-sensitive nerve along (transection of the nerve, introduction to the thickness of the nerve of alcohol, alcohol-procaine mixture of boiling water and mn. other), conductors of pain impulses through the spinal cord, the destruction of the analytical brain structures, denervation of the heart with false angina true because there are no (Author). The results of palliative, recurrent pain.Today remains unsolved phenomenon of recurrence of pain, but more fierce and unquenchable, in the area of the sensitive nerves transected with a scalpel or chemical transection. Such patients are concentrated in the clinic of neurosis or in psychiatric hospitals.B. large-Scale use of painkillers, which are free from pain and suffering only a few minutes. The mechanism is the same. There is milk, eat dairy productioo brain. He loses the ability to transform pain impulses in pain. With the restoration of brain function is restored and pain is still intense.The difference between traditional methods of treatment unquenchable pain from the claimed process easy. They destroy sensitive nerve is the source of pain impulses, and stated how it heals. The Nervina Kozyrev Century A. the drug, he developed, experimentally and clinically tested. Permitted By Farmkomiteta Of The Ministry Of Health. The Nervina deposited around the inflamed nerve, it has a healing effect. Sensitive nerve calms down and the same stops pain impulses infinitely long time. The medicine has no contraindications and no side complications. Filed an application for trademark 25.12.2000,The Nervina Kozyrev C. A. has 6 properties: analgesic, vasodilatory, anti-inflammatory, desensitizing, neurotropic and healing effect on the affected sensitive nerve. Unquenchable pain in the area of the affected nerve instantly disappears for the rest of the life of the patient. The medicine again in the same place, do not enter. Repeat patients does not happen. The patient is given written garancedore trying to enter 10 ml of a 2.0% solution of novocaine, 1.0 ml of 0.02% solution In 12, 1.0 ml of 2.5% aqueous suspension of hydrocortisone, 1.0 ml of a 2.0% solution of papaverine hydrochloride, 1.0 ml of saline.Periradicular injecting the Nervina produce dominant in painful lesions that are detected by palpation designated rear projection sensitive roots of the spinal cord on one side and another side of the vertebrae at the level of L3-L4-S1-S2one injection a day. Periradicular introduction of Nervina exercise stylobate prick of a needle in a dominant pain hearth at an angle of 90oto another in the transverse process. Then tighten the needle 1-2 mm and injected into an angle 80oto get a painful shot in the area of innervation of the sensitive spine. Again tighten the needle of 1 mm and slowly inject 1-2 ml of Nervina. Again tighten the needle 1-2 mm and at an angle 80oimmerse 1-2 mm to obtain pain lumbago, tighten the needle of 1 mm and inject 1-2 ml of Nervina on the one hand sensitive spine. Again tighten the needle 1-2 mm and at an angle of 75oimmerse 1-2 mm to obtain pain lumbago. Again tighten the needle of 1 mm and inject 1-2 ml of Nervina on the other hand sensitive spine.In rezultata. After the renovation of foci of chronic infectious inflammation produce control seeding of them on viral-bacterial flora.When conducting a comprehensive treatment for the claimed method further carry out the increased activity of the immune defense system of the body using three trouble-free natural factors:
A. Regular dosed physical load in a very slow rhythm with the breath on the exhale and the inhale.B. Contrast, regular, morning hydrotherapy gymnastics vessels. This is followed by exercises-massage and wiping massage with a towel.Century In the diet regularly must be citrus fruits, garlic, pepper.On the background of the successful treatment of the patient regressed character personality changes and fear of return unquenchable pain. Normal mental status.After cupping unquenchable pain syndrome is a complex, active and systematic rehabilitation of the knee joint, with increasing volume of active and passive movements and regression neurodegenerative-destructive processes in the knee joint.Example. B the nome joint. Unbearable pain in the morning, at the beginning of the walk, exercise. During the day, the intensity of pain decreases. Day the pain increases sharply when walking the stairs.Disease duration more than 20 years. Long-term, ineffective treatment in outpatient and inpatient neurology Department. In recent years, pain in the lumbar-sacral area are negligible. Dramatically increased persistent pain in the left knee joint, especially in the morning. Started constantly to walk with a stick.In connection with increase in the intensity of pain was admitted to the neurology ward.On the basis of a comprehensive survey diagnosed with osteochondrosis. Sciatica. Herniation of intervertebral disk at the level of L3- L4.Conducted analgesic medication, physiotherapy, acupuncture did not improve the patient's condition.Additional research revealed foci of chronic infectious inflammation left: chronic tonsillitis, catarrhal sinusitis, otitis media, with progressive hearing loss on left ear.In the clinical analysis of blood revealed a leukocytosis of 20,000 HP manual 30 meters is Aries 3-4 lumbar vertebrae. On radiographs of the left knee revealed a narrowing of the joint space, subchondral sclerosis, expressed marginal bone growth, characteristic of osteoarthritis of the knee.Conclusion orthopedist: osteoarthritis of the left knee. Shows the translation of the patient in the casualty Department, for additional examination and surgical treatment.Sick from translation abstained.CT of the spine revealed herniated discs at level 3-4 and 4-5 vertebrae.Consultation of the neurosurgeon: pain radicular compression syndrome. Recommended surgical treatment. From surgery the patient is refrained.Additional neurological examination with palpation of the paravertebral points from two sides revealed the presence of dominant painful lesions at the level of L3- L4- S1- S2on the left side. At these levels in the paravertebral areas palpation of the left formed a stable, round bright spots hyperemia and swelling of the skin.Palpation of the left knee, is defined soreness in the course of the joint space and in the periarticular tissues.Conclusion: Artresources livneh roots of the spinal cord in the lumbar-sacral level to the left, on the side of the sources of chronic inspection toxicity: chronic tonsillitis, allergies, toxic form, chronic periodontal disease, catarrhal sinusitis, otitis left with progressive hearing loss, prostatitis.Produced seeding viral-bacterial flora. Analysis of sowing showed the presence of Staphylococcus aureus high virulence, with the highest sensitivity to Zebrano.Produced readjustment of foci of chronic inflammation. Control seeding viral-negative bacterial flora.For edema dominant painful lesions on the left at the level3- L4- S1- S2used Nervina Kozyrev C. L., cooked extemporal. Before using the syringe gradually gaining 10 ml of a 2.0% solution of novocaine, 1.0 ml of 0.02% solution of vitamin b 12, 1.0 ml of 2.5% aqueous suspension of hydrocortisone, 1 ml of a 2.0% solution of papaverine hydrochloride, 1 ml of physiological solution and during the relief of all dominant painful lesions cancelled permanently receiving painkillers.The Nervina mixed slow change of position of the syringe until a uniform pink color.Palpation reveals a sharp pain in sonrai hyperemia and swelling of the skin, i.e. the dominant painful lesions on 4 levels. They consistently stymied, disposable, starting from the third lumbar sensitive spine.In the dominant pain hearth needle entered stylobate angle 90ountil it stops in the transverse process. Then pulled at 1 to 2 mm and at an angle 80oentered into before getting painful shot in the area of innervation. Again the needle is pulled to 1 mm and slowly entered 1-2 ml of Nervina. After that, the needle is again pulled by 1-2 mm and at an angle of 85oplunged it deep inside to get a pain shot. Again the needle is pulled to 1 mm and put 1-2 ml of Nervina on the one hand sensitive spine. Then the needle again pulled up to 1-2 mm and at an angle of 75odipped in 1-2 ml to obtain pain lumbago. The needle is again pulled to 1 mm and introduced 1-2 ml of Nervina on the other hand sensitive to spine, i.e., injecting drug conducted on three sides periradicular, over sensitive spinal spine with one hand.Unquenchable pain in the area of innervation of the sensitive root after each periradicular injection of Nervina disappears immediately, relapse-free for many years. After treatment unquenchable pain Sint receive guaranteed therapeutic effect, due to the complete coverage of the affected sensitive spine spinal cord.The patient became more confident in the recovery. Regressed fear return unquenchable pain. Threw the crutches. The confident gait. The obvious results of a comprehensive, targeted rehabilitation of the knee joint. No pain in the joint during active movements permits to increase their volumes.Noticeably regressed character personality changes.The patient was discharged in satisfactory condition. Recommended active life: dosed physical load. Tonic, increases the activity of the immune defence system of the body, therapy. Gymnastics, massage, contrast hydrotherapy.Annual comprehensive survey for the past five years confirms complete regression unquenchable pain syndrome arthritisarthritis the knee joint. 1. A method of treating an unquenchable pain syndrome arthritisarthritis, knee joint, including pain management, characterized in that, in accordance with theory of pain Kozyrev Century A. additionally identify and sanitize the foci of chronic infection, then identify the dominant balewa what about the introduction of 3-6 ml of Nervina Kozyrev Century A. preliminarily prepared by mixing 10 ml of 2% solution of novocaine, 1.0 ml of 0.02% solution of vitamin B12, 1.0 ml of 2.5% aqueous suspension of hydrocortisone, 1.0 ml of 2% solution of papaverine hydrochloride, 1.0 ml of physiological solution and during the relief of all identified painful lesions permanently discard all pain medication.2. The method according to p. 1, characterized in that periradicular injecting the Nervina exercise stylebrand the introduction of a needle into the dominant pain hearth at an angle of 90oto another in the transverse process, then tighten the needle 1-2 mm and injected deep into the angle 80oto get a painful shot in the area of innervation of the spinal sensitive spine, re-tighten the needle of 1 mm and slowly inject 1-2 ml of Nervina, re-tighten the needle 1-2 mm and at an angle 80oimmerse 1-2 mm to obtain pain lumbago, re-tighten the needle of 1 mm and inject 1-2 ml of Nervina on the one hand sensitive spine, re-tighten the needle 1-2 mm and at an angle of 75oimmerse 1-2 mm to obtain pain lumbago, re-tighten the needle of 1 mm and inject 1-2 ml of Nervina on the other hand sensitive spine.3. The method according to PP. 1 and 2, characterized in that calinou rehabilitation on recovery of locomotor function of the knee joint and regression neurodystrophic, destructive processes and restoration of tissue structures of the knee joint.4. The method according to PP. 1-3, characterized in that in the process of conducting systematic treatment that increases the activity of the immune system, normalizing mental status, personality changes personality, leveling fear of return unquenchable pain therapy, regular dosed physical activity, self-massage, a cold tub.
< / BR>where AG represents a radical selected from formulas (a) and (b) below:
< / BR>R1represents a halogen atom, -CH3CH2OR SIG7, -OR SIG7, СОR8, R2and R3taken together form a 5 - or 6-membered ring, R4and R5represent H, a halogen atom, a C1-C10-alkyl, R7represents H, R8represents H orX represents the radical-Y-C-, r' and r" is H, C1-C10alkyl, phenyl, Y represents S(O)nor SE, n = 0, 1, or 2, and salts of compounds of formula (I)
< / BR>in which R(1) denotes hydrogen, alkyl with 1, 2, 3 or 4 carbon atoms, alkoxy with 1, 2, 3 or 4 carbon atoms; R(2a), R(2b) and R(2c), which are identical or different, denote hydrogen or alkyl with 1 or 2 carbon atoms; R(3) means hydrogen or alkyl with 1, 2, 3 or 4 carbon atoms; Z denotes sulfur or oxygen; And means phenyl, which is unsubstituted or substituted by up to three identical or different substituents selected from the group consisting of halogen, alkyl with 1 or 2 carbon atoms and alkoxyl with 1 or 2 carbon atoms; or a represents a residue of a saturated or unsaturated lactam of the formula
< / BR>where In means albaniles or alkylene with 3, 4, 5 or 6 carbon atoms, which is not substituted or is substituted by up to three identical or different alkyl groups with 1, 2, 3 or 4 carbon atoms; in all their stereoisomeric forms and mixtures thereof in any ratio; and their physiologically acceptable salts, which are valuable pharmaceutical active substances is I sudden death from cardiac arrest or impact of reduced contractility of the heart, and method of production thereof, and containing pharmaceuticals
SUBSTANCE: method involves carrying out hernia removal in intralaminar way. Posterior longitudinal ligament defect is covered with Tacho-Comb plate after having done disk cavity curettage. Subcutaneous fat fragment on feeding pedicle is brought to dorsal surface of radix and dural sac.
EFFECT: enhanced effectiveness of treatment; reduced risk of traumatic complications.