A method of treating post-stroke paralysis

 

(57) Abstract:

The invention relates to medicine, neurology, and can be used for the treatment of post-stroke paralysis. Conduct electrical stimulation of the receptor apparatus of the deep and superficial sensitivity distal extremities and a corresponding segmental apparatus of the spinal cord. The method allows to increase the effectiveness of treatment of post-stroke paralysis.

The invention relates to medicine, namely to neurology.

There is a method of treatment of paresis by the electrical stimulation of nerves and muscles pulsed current using a multichannel device "Myton" [1]. However, the known method is directed mainly to stimulation of the neuromuscular structures and only indirectly affects proprio and exteroreceptors and peripheral circulation, while the recovery of the neuromuscular system requires sufficient sensory stimulation in the cerebral cortex, increase blood and lymph circulation in the area stimulated tissues.

The closest adopted for the prototype, is a method of treating post-stroke disorders, including stimulation by sequential cyclic eroticheskoe hands; motor point rear flexor of the foot healthy feet and the corresponding area of the affected lower extremity with a repetition cycle for 10 min and additional simultaneous light stimulation [2].

The disadvantage of this method is the lack of maximum proximity of the stimulating pulses to the physiological parameters of the tissue receptor apparatus and involvement in the sanogenesis not all afferent system, but only some of its parts. This leads to a slow recovery of lost motor functions.

The purpose of the invention is the reduction of the period of recovery post-stroke disorders of motor function due to release and stimulation temporarily inactivated and perifocal located nerve cells.

The goal is to reach due to the fact that the impact of the rectangular pulse currents on the receptor apparatus of the deep and superficial sensitivity distal extremities and a corresponding segmental apparatus of the spinal cord.

The associated analysis of the proposed solution with the prototype shows that all the previously described methods were based on stimulation of the motor only the corresponding segmental apparatus of the spinal cord, that allows you to restore lost and generate new functional relationships of cortical-subcortical structures, to improve blood and lymph circulation in the paretic limb, and the reflex influence on the entire body, has a positive therapeutic effect.

The method is as follows. The treatment begins with the patient lying on his back. To apply electrical stimulation apparatus "Wei-1", generating a rectangular pulse current duration of 5 MS and a frequency of 70 Hz. Current 3-4 mA, polarity change after 2 min, the exposure time is 30 minutes

The method of stimulation is as follows: active u-shaped electrodes are superimposed on the distal paretic extremities (toes, and two end interphalangeal joint) and connected by one wire connected to the negative pole. Hydrophilic strip of flannel moistened with warm tap water. The indifferent electrode is placed on the cervical-thoracic spine, those projecting to the corresponding segmental apparatus. Procedure duration 30 min spend every day, the course of treatment consists of 10 sessions.

In this method, the electrostatic damage to the module is Uchenye functional relationships, remove parabolicheskie state, which ultimately contributes to the restoration movement precicesly limbs.

As a result of nonspecific stimulation in the acute and early recovery periods in patients with cerebral stroke appear active motion in paralyzed extremities and increases muscle strength, there is a noticeable positive changes in the emotional-volitional sphere: the sight becomes more meaningful, patients are showing interest in the environment, there is a feeling of inner peace, better sleep. In patients with initially high numbers of blood pressure decrease it by 10-25 mm RT. Art.

The advantages of the proposed method are as follows:

a stimulating pulse characteristics as close as possible to the physiological parameters of the tissue receptor system;

stimulation of the rectangular pulse currents receptor apparatus of the deep and surface species sensitivity distal paretic limbs has a strong sensory irritation in the cortex of the brain, which stimulates temporarily inactivated neurons and makes them vormittag;

actively than focusing on their own segments of the spinal cord, the current when switching polarity at the input and output causes additional irritation that enhances therapeutic effect;

improves blood and lymph circulation in the paretic limbs.

Literature

1. Goldelman M. G., Kramer, A. J. Treatment of diseases of the nervous system. - Tomsk, 1974. S. 174-175.

2. Patent 2040282, A 61 N 1/18.

A method of treating post-stroke paralysis, including the impact of the rectangular pulse currents on the neuro-muscular system of the human body, characterized in that the irritation is applied on the receptor apparatus of the deep and superficial sensitivity distal extremities and a corresponding segmental apparatus of the spinal cord.

 

Same patents:

The invention relates to trauma and is intended for treatment of peripheral nervous system in patients with gunshot wounds and combat injuries

The invention relates to medical technology, specifically the physiotherapeutic devices intended for conducting exercises of the hands, massage, metallelectrotrade palms and Palmar surfaces of the fingers and subcutaneous tissues, including the impact on biologically active points

The invention relates to medicine, and is intended for electrical stimulation of the neuromuscular structures of the pelvis, in particular for the treatment of patients with chronic prostatitis

The invention relates to medicine, namely to cardiac surgery and cardiology, and can be used for the diagnosis and correction of disorders of the Central hemodynamics during electrostimulation of the heart in patients with concomitant disorders atrial and atrioventricular conduction
The invention relates to medicine, more specifically to trauma, and can be used to accelerate the consolidation of diaphyseal fractures of the tibia after a stable immobilization of the fragments

The invention relates to physical therapy and ophthalmology, and is intended for the treatment of diseases in the posterior segment of the eye

The invention relates to agriculture, division of animal health, and in particular to methods and devices for electrical stimulation of the muscles of the uterus and disease in the postpartum period (subinvolution of the genital organs, atony and hypotonia of the uterus, endometritis)
The invention relates to the field of treatment of acute CNS, and in particular to methods of treatment OSPS in children, and can be used in clinical practice
The invention relates to medicine, namely to traumatology and orthopedics

The invention relates to medicine and cosmetics for the treatment of skin diseases and combat its generational changes

FIELD: medicine.

SUBSTANCE: method involves applying transscleral diaphanoscopic examination method for adjusting intraocular neoplasm localization and size. Rectangular scleral pocket is built 2/3 times as large as sclera thickness which base is turned from the limb. Several electrodes manufactured from a metal of platinum group are introduced into intraocular neoplasm structure via the built scleral pocket. Next to it, intraocular neoplasm electrochemical destruction is carried out in changing electrodes polarity with current intensity of 100 mA during 1-10 min, and the electrodes are removed. Superficial scleral flap is returned to its place and fixed with interrupted sutures. 0.1-2% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, transpupillary laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2. the operation is ended with placing sutures on conjunctiva. Platinum, iridium or rhodium are used as the metals of platinum group. The number of electrodes is equal to 4-8. 0.1-1% khlorin solution, selected from group containing photolon, radachlorine or photoditazine, is additionally repeatedly intravenously introduced in 2-3 days at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells is carried out by applying fluorescence and fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, repeated laser irradiation of the intraocular neoplasm is carried out with radiation dose of 30-45 J/cm2.

EFFECT: complete destruction of neoplasm; excluded tumor recurrence; reduced risk of tumor cells dissemination.

3 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: method involves intravitreously introducing two electrodes into intraocular neoplasm after carrying out vitrectomy and retinotomy to expose the intraocular neoplasm. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with current intensity of 100 mA during 1-10 min or 10 mA during 10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2.The transformed retina and tumor destruction products are intravitreally removed. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. Another embodiment of the invention involves adjusting position and size of the intraocular neoplasm in trans-scleral diaphanoscopic way. Rectangular scleral pocket is built above the intraocular neoplasm to 2/3 of sclera thickness with its base turned away from limb. Several electrodes are introduced into intraocular neoplasm structure via the built bed. The electrodes are manufactured from platinum group metal. Electrochemical destruction is carried out with the same current intensity in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. Superficial scleral flat is returned to its place and fixed with interrupted sutures. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg after having carried out vitrectomy and retinotomy. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous laser radiation is carried out in parallel light beam of wavelength equal to 661-666 nm is applied at a dose of 30-120 J/cm2. The transformed retina and tumor destruction products are intravitreally removed using vitreotome. Boundary-making endolasercoagulation of retinotomy area is carried out after having smoothed and compressed retina with perfluororganic compound. The operation is finished with placing sutures on sclerotomy and conjunctiva. Platinum, iridium or rhodium are used as the platinum group metals. The number of electrodes is equal to 4-8.

EFFECT: reduced risk of metastasizing.

4 cl, 13 dwg

FIELD: medicine.

SUBSTANCE: method involves filling vitreous cavity with perfluororganic compound. Two electrodes manufactured from platinum group metal are intravitreally, transretinally introduced into intraocular neoplasm. Electrochemical destruction is carried out with current intensity of 10-100 mA during 1-10 min in changing electrodes polarity and their position in the intraocular neoplasm space, and the electrodes are removed. 0.1-1% aqueous solution of khlorin as photosensitizer, selected from group containing photolon, radachlorine or photoditazine, is intravenously introduced at a dose of 0.8-1.1 mg/kg. Visual control of intraocular neoplasm cells fluorescence is carried out by applying fluorescent diagnosis methods. After saturating the intraocular neoplasm with the photosensitizer to maximum saturation level, intravitreous, transretinal laser radiation of 661-666 nm large wavelength is applied at a dose of 30-120 J/cm2 in perfluororganic compound medium. The transformed retina and tumor destruction products are intravitreally removed with perfluororganic compound volume being compensated with its additional introduction. Boundary-making endolasercoagulation of retinotomy area is carried out. The perfluororganic compound is substituted with silicon oil. The operation is ended in placing sutures over sclerotmy areas and over conjunctiva. Perfluormetylcyclohexylperidin, perfluortributylamine or perfluorpolyester or like are used as the perfluororganic compound for filling vitreous cavity. Platinum, iridium or rhodium are used as the platinum group metals.

EFFECT: complete destruction of neoplasm; reduced dissemination risk.

6 cl, 12 dwg

FIELD: medicine; infectious therapy.

SUBSTANCE: device for plasma-dynamic treatment of infected wounds and cavities has high voltage electric pulse oscillator provided with low-sized high voltage pulse electric-charge unit housed inside carrier dielectric case. The case has co-axial electrode system which has ring-shaped and rod electrodes separated by dielectric insulator. Co-axial electrode system is placed inside optical-transparent quartz member made in form of flask which has perforated semispherical working end. Co-axial system is disposed to have space relatively inner surface of carrier case of unit. Part of internal surface of the unit - at the area of semispherical working end of flask - is made of material which is able to reflect radiation of visible and UF range of spectrum. Removable outlet union, provided with branch pipe connected to union, is mounted onto working part of carrier case of unit. Branch pipe is connected with member having perforated semispherical working end at the opposite side. Opposite edge part of carrier case has support sealing bushing with inlet pipe which is connected with ozone generator conjugated with vessel for containing oxygen. Inlet pipe communicates with space to inner surface of carrier case of the unit and outer surface of flask.

EFFECT: improved efficiency of treatment; improved reliability of operation.

10 cl, 2 ex

FIELD: medical engineering.

SUBSTANCE: device has means for stimulating sensory organs (auditory and visual analyzers), thermo- and mechanoreceptors and transcutaneous electrostimulation in various combinations and sequences. Device has technical means providing sensory irritations. A set of light-emitting diodes comprising white, blue, green, red ones or their combinations are applied in particular for stimulating visual analyzer. Some of them are located on internal surfaces of sun-protection glasses and others arranged on periphery as radial divergent lines. To stimulate auditory analyzer, a set of micro speakers is used, one of which is mounted in the center of head phone and the others are concentrically arranged at least in two rows on periphery. To stimulate mechanoreceptors, a set of infrared light-emitting diodes is used, one of which is mounted in the center of thermode and the others are concentrically arranged at least in two rows on periphery. To carry out transcutaneous electrostimulation, electrodes with centrally arranged contact plate and electrically isolated contact plates concentrically arranged at least in two rows on periphery. Sensory irritation generators have independent communication channels having centrally and peripherally arranged stimulators. The generators are electrically connected to control unit connected to PC.

EFFECT: wide range of functional applications; enhanced effectiveness of human organism mental correction.

2 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: method involves creating therapeutic circuit fixed on patient body, at least two working therapeutic electrodes, measuring and analyzing patient-dependent electrophysical parameters, charging capacitive storage and its later discharging to the working therapeutic electrodes controlled with control unit. Transmitting defibrillation impulse of given power in discharging is carried out in dosed manner first with the first portion W1 of given power dose with the second portion W2 being accumulated on inductive defibrillation power accumulator and then with the second portion W2 of given power dose. Ratio of the first portion W1 of given power dose to the second portion W2 of given power dose of defibrillation impulse is selected from the range of 0.01 to 150. Defibrillation impulse current intensity is selected only when emitting the first portion W1 of given power dose. Cardiodefibrillation impulse is built as bipolar Gurvich impulse. The given power quantity usable for charging the capacitive defibrillator storage is selected to be equal to a value from the range of 4-500 J, defibrillation impulse current intensity being selected from the range of 0.005 to 175 A and voltage equal to a value from 3 to 30000 V. Means has power supply source having unit for controlling charge level of the capacitive storage, unit for building defibrillation pulses, switchboards formed by controlled keys, at least two working therapeutic electrodes and diodes bypassing the controlled keys, resistive current transducer, analog-to-digital converter and control unit having required functional communications to the analog-to-digital converter and controlled keys. The resistive current transducer is in current feeding bus having minimum potential relative to measuring unit under operation having analog-to-digital converter in its structure.

EFFECT: enhanced effectiveness of usage; high safety of patient treatment procedure.

7 cl, 9 dwg

FIELD: medical engineering.

SUBSTANCE: device has n channels where n is even number. Each channel has stimulating signal generator and stimulating signal shaper. The stimulating signal generator has delay unit, unit for blanking coincident signals, packet envelope shaper and pulse packet oscillator. The stimulating signal shaper has power amplifier and unit containing the first starting cell and the first digital display. Unit for determining mean step is introduced into each stimulating signal generator. The unit output is connected to information inputs of delay unit and of stimulating signal shaper. The first input is combined with delay unit input and is called stimulating signal generator Start input. The second one is combined with corresponding delay unit input and packet envelope shaper and is called Set Zero input of the stimulating signal generator. Output of the unit for blanking coincident signals is connected to packet envelope shaper input. I-th stimulating signal generator delay unit output (I=1...n) is connected to i-th input of the unit for blanking coincident signals and serves as output of delayed signals. Inputs of the unit for blanking coincident signals (with the exception of the i-th one) form a group of delayed signals inputs of the stimulating signals generator. Information outputs of the delay unit and of the packet envelope shaper are the first and the second information outputs of the stimulating signal generator, respectively. Packet envelope shaper output is connected to packet envelope generator start input which output is signal output of the stimulating signal generator.

Packet envelope shaper output is processes visualization output of the stimulating signals generator. Each stimulating signal shaper additionally has in series connected attenuator and output transformer symmetric output of which is shaper signal output. Inverter has input connected to power amplifier output. Switch is available between outputs from the power amplifier, inverter and attenuator input. Power amplifier input serves as signal input of the shaper. the second digital display, clock pulse oscillator, the first switch are introduced into movement corrector. The first input of the first switch is connected to clock pulse oscillator output, the output being connected to combined Start inputs of stimulating signals generators having visualization input with its signal inputs being connected to stimulating signals generators processes visualization outputs. The second switch has output connected to synchronizing output of visualization unit input. The third switch has the first and the second outputs connected to the second and the third inputs of the first switch, respectively. Three start transducers make start transducers set with the available one with the first, the second, the third and the fourth outputs are connected to the second and the third switch inputs. The fourth and the fifth switch are available between the first and the second information outputs of stimulating signals generators, respectively. Output of the delayed signals of i-th stimulating signals generator (I=1...n) is connected to inputs of delayed signals group from the remaining stimulating signals generators. Set Zero inputs of the stimulating signals generators are joined together forming movement corrector Set Zero input.

EFFECT: wide range of functional applications; enhanced effectiveness in treating patient possessing heavy locomotor apparatus disorders both in rest state and in moving.

4 cl, 5 dwg

FIELD: medicine, ophthalmology.

SUBSTANCE: the present innovation deals with treating different forms of amblyopia. It is necessary to carry out medicinal correction of neurological disorders in a patient that includes vasoactive preparations, venotonics, nootropes and metabolics. One should conduct electrophoresis of spasmolytics onto area of jugular vertebral department at current power being 0.5-1.0 mA/sq. cm per 10 min, daily. Simultaneously,, it is necessary to carry out argon-laser stimulation of retinal central area and projection of papillo-macular bundle, about 150-200 impulses/seance, radiation power being 0.05 W, radiation diameter of 1000 mc, exposure time of 0.01 sec, wave length being 498-514 nm every other day. Therapy course lasts for 10 d. The innovation enables to achieve positive dynamics in treating severe forms of amblyopia, restore visual function and obtain correction of neurological disorders.

EFFECT: higher efficiency of therapy.

4 ex

FIELD: medical equipment, applicable for treatment of various inflammatory diseases.

SUBSTANCE: the device has a noise current generator, catheter, series-connected personal computer, control unit and a filter unit, whose input is connected to the output of the noise current generator, the output is connected to the catheter, and the personal computer is provided with a dialogue software of experiment planning.

EFFECT: provided approximation of the frequency spectrum of the current acting on the man organs and tissues to the therapeutically optimal value by determination of the optimal combination of the tuning frequencies and the quantity of filters by the methods of mathematical planning of experiment with employment of a personal computer.

1 dwg

FIELD: medicine.

SUBSTANCE: method involves introducing photosensitizer in pharmaceutical water-soluble dosage form at a dose of 1.5-2.0 mg/kg * 0.7 during 40-60 min. Blood is concurrently exposed to laser radiation at a dose of 600-900 J/cm3. The wavelength is selected to match photosensitizer absorption maximum in the water-soluble dosage form. Chlorine row photosensitizer is introduced 3-3.5h later in liposome form at a dose of 1.5-2.0 mg/kg*0.3. 15 min later, laser radiation is applied all over the whole tumor perimeter in transpupillary mode with neighboring fields overlap by 5% of area with power density of 80-100 J/cm2. The wavelength is selected to match photosensitizer absorption maximum in the liposome form. Then the whole neoplasm surface is irradiated in transpupillary mode in laser radiation fields in circle moving from periphery to the center with neighboring fields overlap being equal to 5% of area. The wavelength is selected to match photosensitizer absorption maximum in the water-soluble dosage form. Power density of 80-100 J/cm2 in peripheral part is gradually increased when moving towards the center to 100-120 J/cm2. Two weeks later, localization is adjusted in diaphanoscopic transscleral way and electrochemical destruction of intraocular neoplasm is carried out with current intensity of 10-100 mA during 10-1 min.

EFFECT: enhanced effectiveness in achieving complete or partial tumor regress; reduced risk of metastatic complications.

4 cl

Up!