Method of preparation for hyperbaric oxygen therapy patients with coronary heart disease

 

(57) Abstract:

The invention relates to medicine, particularly cardiology, and can be used to prepare for hyperbaric oxygen therapy patients with coronary heart disease. To do this, additionally within 10-14 days before the course hyperbaric oxygen therapy patients are therapy with antioxidant - Trimetazidine or-tocopherol. The method helps to prevent excessive activation of lipid peroxidation when conducting hyperbaric oxygenation and prevent the development of associated complications.

The invention relates to medicine, particularly cardiology, and can be used to prepare for hyperbaric oxygen therapy patients with coronary heart disease.

The known method of preparation for hyperbaric oxygen therapy patients with coronary heart disease, which is essentially an isolated course of treatments hyperbaric oxygen therapy (hyperbaric oxygenation Ed. by S. N. Epuni, M.: Medicine, 1986, 416 S.).

The disadvantage of this method is the lack of prevention of excessive activation of lipid peroxidation in hipe complications during the course of hyperbaric oxygenation.

There is a method of preparation of hyperbaric oxygenation of patients with ischemic heart disease, taken as a prototype, in which hyperbaric oxygen therapy in patients with ischemic heart disease applied on the background of the ongoing antianginal therapy of nitroglycerin (Ashurov L. D. Hyperbaric oxygen therapy in treatment of chronic ischemic heart disease: summary Diss. Kida. the honey. Sciences. - M., 1979, 16 S.).

The disadvantage of this method is the lack of prevention of excessive activation of lipid peroxidation during hyperbaric oxygenation, which in some patients may cause exacerbation of ischemic heart disease and the development of complications during the course of hyperbaric oxygenation.

The essence of the invention lies in the fact that according to the method of preparation of hyperbaric oxygenation of patients with ischemic heart disease, including the use of drugs, additionally within 10-14 days before the course hyperbaric oxygen therapy patients are therapy with antioxidant action.

The use of this method of preparation of hyperbaric oxygenation in patients with Isami barbarically oxygenation and prevention of related complications during the course of hyperbaric oxygenation.

The method is performed in the following way: within 10-14 days prior to the commencement of a course of hyperbaric oxygenation in patients with ischemic heart disease additionally conduct therapy with antioxidant action (Trimetazidine or-tocopherol).

Examples of specific implementation of the method.

Example 1. Patient M., aged 45, diagnosed with Coronary heart disease, angina, FC-III, H-I. the Intensity of lipid peroxidation before treatment method chemiluminescence 168 imp/s In patients receiving nitrates started a course of hyperbaric oxygenation. After the 2nd procedure reported increased anginal pain, which coincided with increased lipid peroxidation up to 194 imp/s Rate hyperbaric oxygen therapy temporarily discontinued, further appointed antianginal drugs.

Example 2. Patient F., 53 years old, diagnosis: Ischemic heart disease, angina, FC-II, N is 0. The intensity of lipid peroxidation before treatment method chemiluminescence 162 imp/s in Addition to used sick nitrates assigned Trimetazidine 60 mg/day for 14 days, then started a course of hyperbaric oxygenation. A course of hyperbaric oxygenation proceeded without complications is.

Method of preparation for hyperbaric oxygen therapy patients with coronary heart disease, including the use of drugs, characterized in that it further within 10-14 days before the course hyperbaric oxygen therapy patients are therapy with antioxidant action.

 

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