A method for the treatment of nonhealing wounds

 

(57) Abstract:

The invention relates to medicine, in particular to surgery, and can be used for the treatment of nonhealing wounds. In the first phase of wound healing sessions are conducted by aeroionotherapy within 10-25 days. In the second phase before the dressing is applied with a water-soluble ointments to the wound transplanted culture alloparental on film the matrix. The method allows to activate regenerative processes in the wound. It provides complete wound healing.

The invention relates to medicine, in particular to methods for treating nonhealing wounds.

Known methods of treatment of nonhealing wounds with the help of enzymes, for example, iruxol (see M. A. Trunin, A. S. Emelianov, "Application of iruxol in the surgical clinic". J. "Surgery", 1982, No. 8, page 88), trypsin (see P. I. Tolstykh and other "Influence of bioactive dressing coatings wounds in the course of the wound process. J. "journal of surgery", 1987, No. 3, page 57).

However, the use of enzyme preparations promotes cleansing of the wounds of necrotic tissue, fibrinous plaque, purulent discharge, but does not affect the processes of regeneration and epithelization of wounds.

However, the known method allows only to arrest the inflammatory process in the wound in the first phase of wound healing and has no direct effect on epithelialization.

The task of the invention is the activation of regenerative processes in the wound.

The problem is solved by a method which includes applying bandages with a water-soluble ointments, in the first phase of wound healing sessions are conducted by aeroionotherapy to the magnitude of the flow of ions from 15 to 40 μa within 10-25 days, and during the second phase before the dressing is applied with a water-soluble ointments to the wound transplanted culture alloparental on film the matrix.

A method for the treatment of nonhealing wounds is as follows. In the first phase of wound healing after using the toilet of the wound and surrounding skin hold sessions aeroionotherapy. The flux of ions is set in the range from 15 to 40 μa depending on haraga process on the wound after using the toilet and its surrounding skin with antiseptic solutions carry alleyball on film the matrix, and on top dressings with saline solution. Through the day the film the matrix is removed and the wound dressings with the coated water-soluble base (type the vegetable "levomekol). Subsequent ligation is performed through the day. Sessions aeroionotherapy can be continued after applying to the wound culture alloparental.

Clinical example. Zhikhareva, A. F. 64 years, and. b. N 191744 entered NIETO diagnosed with nonhealing wound right leg after mechanical injury, bronchial asthma. Local status: in the lower third of the right tibia on the background of the changed skin has wound size 1.5 x sm Bottom of the wound are sluggish, Sclerotinia covered with fibrin granulation. The edges of the wound scar changed, the signs of epithelialization not expressed. Cytologically destroyed fiber, detritus, the cell elements are presented in the form of single dystrophic changes of neutrophils (dystrophic cellular reactions). Duration wounds - 3 months. At the first stage of treatment to cleanse wounds from a deathly affected tissues, stimulation of microcirculation in the wound, a course of conservative therapy, including aeroionotherapy for 22 days. The result is no. Cytologically: detritus in small quantities, single fiber, cellular elements represented by a large number of neutrophils different degree of degradation and single polypectomy (3-5%), lymphocytes. In the second phase of wound healing on the wound surface transplanted allogeneic fibroblasts in the film the matrix, above the bandage was applied with a solution of hydrocortisone. Film from the surface of the wound removed after 1 day, then ligation was performed every other day with water-soluble ointments. On the 5th day after transplantation alloparental the size of the wound was reduced to 0.5 x 1 cm, there is a marked edge epithelialization, wound fundus are bright juicy granulation, no plaque, detachable scarce. Cytologically: cellular elements abundant, the number of Poliplast increased 10-fold and is 45-50%, neutrophils, lymphocytes, isolated macrophages, detritus in small quantities (regenerative type of cell reaction). Complete epithelialization occurred 12 days after transplantation alloparental.

The method allows to optimize the course of the wound process in all phases and provides a complete healing of nonhealing wounds.

A method of treating the long Nazarova the ECCA conduct sessions aeroionotherapy within 10-25 days in the second stage, before the dressing is applied with a water-soluble ointments to the wound transplanted culture alloparental on film the matrix.