A method for the treatment of chronic and subacute thyroiditis

 

(57) Abstract:

The invention relates to medicine. A method of treatment of chronic and subacute thyroiditis with use of the drug "Eldarin". The method allows the simultaneous long-term to control the autoimmune process in the thyroid gland and inflammation in the respiratory tract in the absence of systemic side effects from treatment.

The invention relates to medicine, namely to endocrinology and clinical immunology, and can be used in the practice of the treatment of chronic and subacute thyroiditis occurring with concomitant diseases of the upper respiratory tract.

There is a method of treatment of subacute and chronic thyroiditis with the use of oral, intramuscular and intravenous corticosteroids. Each of these methods has a positive therapeutic effect on autoimmune lesions of the thyroid gland, however, acting systemically, leading to the development of complications from the use of corticosteroids.

The prototype was taken treatment of systemic glucocorticosteroids in patients with graves ' disease who are receiving antithyroid drugs (Abstract journal 1999 the steroids on the body, leading to the development of side effects;

the impossibility of long-term use of this therapy due to the development of side effects.

The basis for the development of the proposed method formed the high frequency of occurrence of chronic inflammatory diseases of the respiratory tract (86% of cases) among patients with autoimmune thyroiditis and their pathogenetic role in maintaining inflammation in the thyroid gland. The method is as follows: the treatment of subacute and chronic thyroiditis with concomitant diseases of the upper respiratory tract is carried out with use of betamethasone in the spray (Aldarin", the firm Schering-plough). The duration of treatment from 3 to 6 months on one breath for 2-3 seconds 3 times a day. Evaluation of the patient after treatment is conducted by ultrasonography of the thyroid gland, the levels of total blood analysis, palpation studies of the thyroid gland.

Example 1. Patient K., 36 years. History 5122 were treated at the clinic medical unit 7 with a diagnosis of Chronic autoimmune thyroiditis. Multinodular goitre 3 degrees with symptoms of thyroiditis. Bronchial asthma infectious-allergic, easy form. Significant effect ticosteroid in the spray (aldarin) 1 breath for 2-3 seconds 3 times a day for 3 months. In the treatment of the symptoms of thyrotoxicosis disappeared, hormones T4, T3 normalized, the thyroid gland decreased in size up to 2 degrees. The consistency of the gland was soft.

Example 2. Patient M 45 years. History 5498. Went to the polyclinic medical unit 7. The diagnosis of Subacute thyroiditis. Chronic pharyngitis. Ambulatory patient designated spray aldarin 1 breath for 2-3 seconds 3 times a day. After 2 weeks the condition was considerably improved. Pain in the thyroid gland disappeared. Normalized readings: erythrocyte sedimentation rate, white blood cell count. Treatment continued for up to 3 months. When re-examination after 3 months - the thyroid gland is soft, elastic, painless.

The method is simple, available, cheap, and can be recommended in medical practice. A significant advantage of the proposed method is the possibility of simultaneous long-term management of autoimmune process in the thyroid gland and inflammation in the respiratory tract in the absence of systemic side effects from treatment.

A method for the treatment of subacute and chronic thyroiditis in individuals with concomitant diseases of the upper respiratory tract glucocorticosteroids, characterized in that wodn.

 

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