The method of stimulation of reparative regeneration of tissues with their injuries and diseases

 

(57) Abstract:

The invention relates to medicine and can be used in the treatment of patients with lesions in the tissues of various etiologies. The method involves the use of donor blood collected from donors in the tissues of the extremities of the osteosynthesis create conditions voltage. Use drugs, prepared on the basis of this blood. The method provides a faster regeneration of damaged tissue.

The invention relates to medicine and can be used in the treatment of patients with injuries and diseases of tissues and body of various etiologies.

There is a method of stimulation of reparative regeneration of tissues (1) by exposure to a magnetic field.

However, using this method connected with necessity of special equipment, which is not always possible, and the resulting therapeutic effect in some cases is limited or only after a certain time after conducting several courses of magnetotherapy.

It is also known to stimulate reparative processes blood and drugs, setdatabase, in particular:

film febrina isogenic (from blood), consisting of fibrin derived from fibrinogen plasma donor human blood and soaked in 70% aqueous solution of glycerin;

- biological swab antiseptic made from plasma donated blood, gelatin, antimicrobials, chloride of calcium and thromboplastin;

- sponge febrina isogenic containing fibrin, thrombin and protein included in the first fraction of the plasma proteins.

These and other preparations made on the basis of donor blood and donor blood in its pure form is used in operations and traumatic injuries to close extensive scalped wounds, defects of the skin, burns, trophic ulcers, to prevent adhesions in various abdominal operations, when the damage to the skull and brain, for filling bone cavities, bleeding, etc.

According to well-known indications of donor blood and products manufactured on its basis, are applied topically, injected intravenously and intramuscularly, as well as oral and have a healing effect on damaged tissue.

The objective of the invention is the alawneh.

This task is solved in that in the method involving the use of donor blood and products manufactured on its basis, use blood donors of tissues which during osteosynthesis create conditions voltage.

New in the proposed method is that for the stimulation of reparative processes in tissues with their diseases and injuries use blood donors of tissues which during osteosynthesis create conditions voltage that gives the opportunity to judge its compliance with the criterion of "novelty".

The analysis of available sources of information on the use of donor blood and products manufactured on its basis, for the stimulation of reparative processes shows that the proposed technical solution is not obvious and does not follow what has been achieved in this field of knowledge. This allows to make a conclusion on the conformity of the proposed method the criterion of "inventive step".

The applicability of the method is confirmed by the fact of its successful use in RISC "RTO" named after academician G. A. Ilizarov.

The method is as follows.

During treatment of injuries and diseases of the integumentary orskog blood or drugs, made on its basis. At the same time as blood use blood donors who perform osteosynthesis of bones of the limbs with the creation in the tissues of the latest stress conditions, i.e. conditions that are created when dosed compression or distraction of the bone fragments damaged or reconstructed limb. From the same blood prepared by known methods and products based on it: albumin, protein, film febrina etc.

Thus obtained blood and established on the basis of the drugs in the future use of traditional schemes to produce clinically significant positive treatment outcome.

The method can be applied to treat wounds, ulcers of various origins, skin diseases, diseases of internal organs.

As an illustration of the complete method given the following experimental observation.

Example 1.

The dog, the age at the time of surgery 2 years; to study the incentive effects of blood on healing modeled wound on the left thigh size 4x6 see a Similar defect in epithelial tissues has been created in the control animal.

For RSOI blood, taken from the experimental animal, the dog, which in this period was made distraction osteosynthesis dosed elongation of one of the limbs. Processing was performed according to the traditional scheme.

Control animal handling wound surface, also under the traditional scheme, was carried out by normal donor blood.

The first animal, the wound healed within 8 days, the second for - 12. Similar experiments were performed in the study of the stimulating effect of blood and drugs, created on its basis on reparative regeneration of tissues of internal organs. In all cases, the healing process was much faster when using blood and drugs made based on it, when donors have used animals that were performed osteosynthesis limbs with them create stress conditions.

Driven clinical observation.

Example 2.

Patient D. , aged 47. Diagnosis: Atopic Dermatitis. Localization of lesions on the hands.

Patient three times during the week, put a bandage with blood plasma of the animal, which was extended leg. After a week showed a significant improvement, and further the loci for the Yu reparative tissue regeneration with their injuries and diseases.

Sources of information taken into account

1. Detlev I. E. Some data about the use of electromagnetic fields in the treatment of bone fractures in patients with the imposed external fixation apparatus/Apparatuses and methods of external fixation in trauma and Orthopaedics. So 2. - Riga, 1985. - S. 146-149.

2. Handbook of transfusion of blood and blood substitutes. M, Medicine, 1982. C. 76-93.

The method of stimulation of reparative regeneration of tissues with their injuries and diseases, including the use of donor blood and products manufactured on its basis, characterized in that use blood donors of tissues which during osteosynthesis create conditions voltage.

 

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