The method of treatment of malignant neoplasms and device for its implementation
(57) Abstract:The invention relates to medicine, and is intended for the treatment of malignant tumors. Made of plates of pure graphite electrodes placed on the patient's body through a strip of hydrophilic material, moistened dissolved in the silver water juice of sea buckthorn and aloe. Control over their introduction into the body are carried out by the time of the procedure, the minimum value is calculated individually for each patient based on measurements of the distance between the electrodes and the calculated speed of the ions of anticancer drugs, which depends on the measured potential difference between the electrodes, the density of direct current should not exceed 0.1 mA/cm2. The method allows to increase the effectiveness of treatment of malignant tumors. 1 Il. The invention relates to medicine and can be used for therapeutic treatment of cancer.There is a method of treatment of lung cancer, in which the surface malignancies through the bronchoscope put the anticancer drug, and then using iontophoresis is the first disappearance of the solution from the surface of the tumor (RF patent 2115445, class A 61 N 1/30, 1998). The disadvantages of this method include the complexity of drug administration into the body and the unreliability of visual monitoring of the Deposit.The closest to the essence of the proposed method is a method of treatment of metastases of malignant tumors, in which the patient's body in the area of metastases injected anticancer medication, and then put on the body electrodes create an electric field which, in contact with the dipoles of the solvent enters the drug in cancer. Control is carried out by the magnitude of the current (RF patent 2117500, class A 61 N 1/30, 1998). The disadvantages of this method include limited use in the treatment of tumors located deep in the body, and the lack of control the duration of the procedure.The closest to the proposed device is a physiotherapy device "Thread-1" containing the constant current source, the output of which through the adjustment potentiometer is connected with the output terminals of the apparatus, and in the chain sliding contact of the potentiometer cascaded milliammeter, and output terminals of the device using perished who incorporates both a flexible lead plate and hydrophilic fabric strip, protruding from all sides by the edges of the plate 20-40 mm (K. Y. Yuldashev, Y. A. Kulikov. Physiotherapy. Tashkent, IEP them. Ibn Sina, 1994, S. 31, 32, Fig.1). The disadvantage of this device include the inability to measure the potential difference between the electrodes required for controlling the time of the procedure, and the use of the electrode lead plates in connection with the toxicity limit the duration of the procedure.The technical result of the proposed method of treatment using the proposed device is to increase the effectiveness of treatment due to the full implementation of malignant neoplasm of specially selected anticancer drugs of chemical origin at the time of the procedure, calculated individually for each patient, and the refusal of the application in the device of toxic materials.This result is achieved in that the application of the method of treatment of malignant tumors, including the introduction into the organism by iontophoresis (electrophoresis) anticancer drugs, in which electrodes through the strip of hydrophilic material, moistened with anticancer drugs, as a Second, fermented floral honey, impose on the patient's body on both sides of malignant neoplasms, create an electric field and supervise the introduction of drugs into the body as the value of the current intensity and the amount of time of the procedure, the minimum value is calculated individually for each patient based on measurements of the distance between the electrodes and the magnitude of the potential difference between them. In a device for the treatment of malignant tumors, containing the constant current source, the output of which through the adjustment potentiometer is connected to the output terminals, and the circuit of the sliding contact of the potentiometer series measuring current, and output terminals of the device using flexible insulated conductors connected respectively with two patch electrodes, each of which includes a flexible plate made of conductive material and the hydrophilic fabric strip, protruding from all sides by the edges of the plate, put the probe potential difference, are connected in parallel to the output terminals of the device, as the conductive material in the overhead electrode IP neoplasms shown in the drawing.The device comprises a source 1 DC in parallel, the outputs of which are connected potentiometer 2, one of constant contact and sliding contact of which is connected respectively with the output terminals 3 of the device, and the chain sliding contact consistently included milliammeter 4, parallel to the output terminals 3 are connected voltmeter 5, and the output terminals 3 devices using flexible insulated conductors connected respectively with two patch electrodes 6, each of which includes a flexible plate 7 made of pure graphite and hydrophilic fabric strip 8, protruding from all sides by the edges of the plate.The treatment process is as follows. Under the electrodes 6 enclose strip of hydrophilic material, moistened with a solution of silver water set concentration of activated juice of sea buckthorn and aloe, fermented floral honey, and place them on the patient's body so that the flow of ions medicines to send in an area of malignant neoplasms. Measure the distance between the electrodes 6 and serves them from source 1 constant current setting potentiometer 2 and kontrolirovat 0.1 mA, and then with a voltmeter 5 measure the potential difference between the electrodes 6.It is considered that when the potential difference between the electrodes 6, is equal to 3, the ions are moving with an average speed of about 1 mm/min was empirically found that the change of the average velocity of the ions is directly proportional to the change in the potential difference between the electrodes 6. Thus, calculating the speed of movement of the ions of medicines in the body of the particular patient based on the measured potential difference between the electrodes 6 and knowing the distance between the electrodes 6, calculate the minimum time for the treatments of iontophoresis. A longer duration of the procedure against the settlement is not contraindicated, but instead gives a more pronounced therapeutic result. Since the calculated minimum treatment time significantly exceeds the amount recommended by traditional treatments of iontophoresis, the use of electrodes 6 lead plates becomes invalid. Using the same electrodes neutral pure graphite instead of toxic lead can not limit the time of the procedure.Medicines are selected so Method and device for the treatment of malignant tumors can be illustrated by the following examples.Example 1. Patient A. A., born in 1947. From the anamnesis: severe inflammation in the oral cavity. Strong swelling, slurred speech. After histological examination was diagnosed with adenocarcinoma of the submandibular salivary glands. The patient began treatment in the hospital, where he conducted a course of radiation therapy, but the positive results are not achieved. From the proposed heavy replacement surgery of the lower jaw refused. After four treatments of iontophoresis with the introduction in the area of the mass of the solution in the silver water set concentration of activated juice of sea buckthorn and aloe, fermented floral honey, was pronounced positive effect. Histological examination of the presence of malignant cells is not shown.Example 2. Patient L. Y., 1956. Was observed in the Cancer center. N. N. Blokhin. Detected malignant neoplasm of breast cancer III stage. Was prepared for surgery removal of the breast, pectoral muscles and the nearby package of lymph nodes. Having heard about the possibility gentle method of treatment is the group in the area of neoplasms of the solution in the silver water set concentration of activated juice of sea buckthorn and aloe, fermented floral honey. Pronounced positive effect appeared three weeks later. Complete recovery occurred after 7 months.Example 3. Patient L. I., born in 1935. From the anamnesis: on the middle of the forehead above the left eyebrow rounded education 2.0-2.5 cm dark color with a dense homogeneous structure with a filamentous growth form, pointing towards the nose. After a call to the oncologist and conducted analyses revealed that the tumor was malignant, and the diagnosis of melanoma forehead. Treatment of a tumor by iontophoresis using solution of silver water set concentration of activated juices of medicinal plants antitumor activity (sea buckthorn and aloe, fermented floral honey) has led to positive results. After the first treatment, the tumor has shrunk by more than half. There were three treatments, then remained barely noticeable trace in the form of a dark spot of 5 mm and diameter. The tests showed no presence in it of malignant cells. The method of treatment of malignant tumors, including the introduction into the organism by iontophoresis of anticancer drugs, in which electrodes placed on the body of patient education, create an electric field and supervise the administration of the drug in the body, characterized in that the plates of pure graphite electrodes placed on the patient's body through a strip of hydrophilic material, moistened dissolved in the silver water juice of sea buckthorn and aloe, and control their introduction into the body are carried out by the time of the procedure, the minimum value is calculated individually for each patient based on measurements of the distance between the electrodes and the calculated speed of the ions of anticancer drugs, which depends on the measured potential difference between the electrodes, the density constant current should not exceed 0.1 mA/cm2.
FIELD: medical engineering.
SUBSTANCE: device has container for keeping product to be applied, dosing unit for distributing the product, power supply element placed near the dosing unit. The dosing unit is designed as rotating element and is apiece of felt. Container walls are flexible. The dosing unit is manufactured from electric conducting material and connected to the power supply element.
EFFECT: enhanced effectiveness in carrying out viscous product iontophoresis.
8 cl, 7 dwg
FIELD: medicine, juvenile surgery.
SUBSTANCE: the method is characterized by the fact that 3 wk before surgical dissection of adhesions due to laparoscopy one should prescribe bifiform per 1 capsule and Hilak-Forte per 10-15 drops thrice daily. Moreover, 7 d before surgical interference it is necessary to conduct 7 seances of electrophoresis with irucsol and prescribe smekta sorbent per 1 packet thrice daily. Then comes laparoscopic dissection of adhesions, and after surgical interference one should perform electrophoresis with irucsol for 7 d. After appearance of intestinal peristaltics it is necessary to apply smekta per 1 packet thrice daily for 7 d. Since the 8th after operation one should prescribe bifiform per 1 capsule and Hilak-Forte per 10-15 drops thrice daily for 1 mo. Then 1 mo after laparoscopy one should prescribe electrophoresis with collalysine up to 8-10 procedures at simultaneous abdominal massage and curative-physical culture complex for 8-10 d. The method enables to obtain antiadhesive effect in 92% cases of surgical dissection of adhesions due to complex impact upon pathogenesis of adhesive disease, at decreased number of relapses.
EFFECT: higher efficiency of therapy.
SUBSTANCE: method involves introducing oxybutinine solution into the urinary bladder via catheter in the amount of 5-10 mg per 20-30ml of sterile water once a day. Electrophoresis is concurrently carried out on the urinary bladder projection region using current intensity of 0.02-0.04 mA/cm2 during 15-20 min. The total treatment course is 10-12 daily procedures long.
EFFECT: enhanced effectiveness of treatment.
SUBSTANCE: method involves placing active electrode like metal conductor in canal and passive electrode on body surface zone and applying DC action. The metal conductor is coated with dielectric layer spread to its working part. The working part is brought close to impassable area through badly or well-passable zones of the root canal. Gap filled with electrolyte is left between the impassable area and electrode end. The active electrode is connected to electric current source plus terminal and the passive one to minus terminal.
EFFECT: enhanced effectiveness of treatment.
SUBSTANCE: method involves dropping 1% midriacyl solution into conjunctival cavity in postoperative period. Then, lidase electrophoresis is applied to orbicular muscle zones. Plaster wetted with Okovidit gel is applied to the lower eyelid.
EFFECT: accelerated treatment course.
FIELD: medical engineering.
SUBSTANCE: device has reservoir, containing medicament, with electrode fixed therein. The device is to be held with patient hand. Eye-bath end surface designed for making contact with orbit boundary is of oval shape having broad and narrow end approximating orbit form. The narrow eye-bath end is raised above its broad end. The electrode is removable and remountable. The eye-bath is manufactured from flexible biologically neutral thermosetting polymer stable with respect to temperature and medicament action.
EFFECT: improved adjacency to orbit in performing electrophoresis procedures.
FIELD: medicine, endocrinology.
SUBSTANCE: at the background of applying microdosages of iodine and/or levothyroxine one should conduct electrophoresis with 3%-sodium thiosulfate solution. The latter should be introduced with the help of a cathode placed onto thyroid area, an anode - onto interscapular area. The area of the interlayer corresponds to 5 x 10 cm at current power being 4-8 mA, exposure time being 15-20 min. Seances should be performed either daily or every other day, about 10-12 procedures/course.
EFFECT: higher efficiency of therapy.
FIELD: physiotherapy and health resort treatment.
SUBSTANCE: method envisages drinking mineral water, performing intragastric electrophoresis with mineral water, magnet-laser therapy, massage, and baths. Additionally, 2-3 days before physiotherapy and during physiotherapy, biologically active additive "succinic acid" is administered in daily dose 3 x 0.5 g after meal. Intragastric and magnet-laser therapy are performed every day consecutively without interval between them. Treatment course consists of 8-10 procedures. Method allows achieving stable remission in case of indicated diseases thanks to integrated positive effect produced on inflammatory process, velocity of epithelization of ulcerous and erosive defects, acid-forming, neutralizing, and motor functions in gastroduodenal region on the whole.
EFFECT: enhanced treatment efficiency.
5 tbl, 2 ex
FIELD: medicine; infectious therapy.
SUBSTANCE: device for plasma-dynamic treatment of infected wounds and cavities has high voltage electric pulse oscillator provided with low-sized high voltage pulse electric-charge unit housed inside carrier dielectric case. The case has co-axial electrode system which has ring-shaped and rod electrodes separated by dielectric insulator. Co-axial electrode system is placed inside optical-transparent quartz member made in form of flask which has perforated semispherical working end. Co-axial system is disposed to have space relatively inner surface of carrier case of unit. Part of internal surface of the unit - at the area of semispherical working end of flask - is made of material which is able to reflect radiation of visible and UF range of spectrum. Removable outlet union, provided with branch pipe connected to union, is mounted onto working part of carrier case of unit. Branch pipe is connected with member having perforated semispherical working end at the opposite side. Opposite edge part of carrier case has support sealing bushing with inlet pipe which is connected with ozone generator conjugated with vessel for containing oxygen. Inlet pipe communicates with space to inner surface of carrier case of the unit and outer surface of flask.
EFFECT: improved efficiency of treatment; improved reliability of operation.
10 cl, 2 ex
SUBSTANCE: method involves applying decompression cholecystostoma over the gallbladder. Gallbladder lavage is carried out using the cholecystostoma. Then gallbladder cavity is filled with antibacterial preparation. Electrophoresis is carried out directly in inflammatory changed area through electrodes mounted corresponding to preparation polarity in the gallbladder cavity and externally on patient skin in hepatobiliary organs projection zone.
EFFECT: accelerated treatment course.