The tool hitoha", which has an immunomodulatory and anti-allergic action (options)

 

(57) Abstract:

The invention relates to medicine, namely to the field creating means, which has an immunomodulatory and anti-allergic effect, and can be used to treat a wide range of diseases. The proposed group of inventions. The compositions contain vitamin C, a filler, a powder of Salsola Collina in one case and a dry extract of Salsola Collina in another. The drug improves heart, lowers cholesterol and blood sugar, prevents the formation of blood clots, corrects the gastro-intestinal tract. 2 S. and 2 C.p. f-crystals.

The invention relates to the field of medicine and for the creation of agents that have immunomodulatory and anti-allergic action, which can be used to treat a wide range of diseases.

In recent times, especially popular drugs based on chitosan is a polysaccharide consisting of parts of 2-amino-D-glucose and partially N-acetylglucosamine. This is a product of natural origin obtained by deacetylation of chitin of crab shells.

In world practice, chitosan is used as a main component different anti-allergic, immune stimulating, absorbing action. Water-soluble forms of chitosan with collections of medicinal plants, is presented in the form of Hittisau, were successfully used for the treatment of various diseases.

Collection of herbs, which is part of phytochitodes tailored to their pathogenic mechanisms: antiviral, antioxidant, cholelithiasis, activation interferonogenesis, inhibition of proteolysis. The largest economic costs to obtain phytochitodes different combinations of herbs and fees depending on the clinical course of the disease make these dosage forms drugs XXI century (see Pogorelskiy L. C., and others, the Materials of the 1st scientific conference of Moscow phytotherapeutic society, 16-17 September 2000, S. 38).

The present invention is the creation of tools immunomodulatory and anti-allergic effects for the treatment of a wide range of diseases.

To solve this problem is proposed group of inventions, namely options immunomodulatory and anti funds.

The proposed tool is made in pill form and contains grass powder Salsola Collina, chitosan, willoway - 200

Chitosan - 45

Vitamin C - 10

Filler - 45 (variant 1)

When the filler comprises microcrystalline cellulose, calcium stearate, and starch.

option 2, the proposed means contains dry extract of Salsola Collina, chitosan, vitamin C and a filler at a ratio, mg:

Dry extract of Salsola Collina - 25

Chitosan - 25

Vitamin C - 10

Filler - 240

The filler comprises microcrystalline cellulose, calcium stearate, and starch.

Known drugs on the basis of Salsola Collina herb tea, extract, dry extract and use as hepatoprotector (see kN. "Aditi your liver" H.To. Lunak etc., M., 1999, pp. 19-20).

Medicinal properties of Salsola Collina is due to the content of substances that may exert some influence on the whole organism and its organs and systems. It contains the following classes of compounds: flavonoids (tricin, isorhamnetin, quercetin, rutin), polysaccharides, carotenoids, sterols, lipids, amino acids, trace elements.

Of particular interest is the presence in it of branched chain amino acids, actively participating in the life of the brain.

The effectiveness of this treatment of hepatocytes obvious and gives unexpected results in the pathology of other organs and systems, having in mind the metabolic nature of the mechanism of action.

Brine Holloway found more than 14 micro - and macro-elements: Si, CA, CR, Mn, Fe, cu, Zn, S, P, Na, Mg, K.

Among them it is necessary to note the unusually high content of potassium (up to 4410 mg/l in liquid form), phosphorus, calcium, magnesium (as is the treatment of coronary artery disease with high cholesterol). Silicon 50 mg/l skeletogenesis element fiber and fade in the process of human life, which is one of the reasons "dragline" of the body. Copper deficiency in the body leads to anemia.

The presence of brine Holloway polysaccharides, namely homopolysaccharides D-fructose, called in biochemistry by inulinase, and homopolysaccharides D-mannose-maņana, gives the opportunity to offer positive effect of Salsola Collina diabetes, which has been proved in clinical practice (N.To. Lunak "Protect your liver), 1999, pages 14-15). The uniqueness of Salsola Collina is that it has a wide range of biologically active substances, blahop aetsa relevant.

Held in recent years, studies of the natural biopolymer chitosan showed some of its unique properties.

Chitosan absorbs fat and cholesterol already in the digestive tract, thereby reducing the caloric content of food and excretes them in undigested form. One molecule of chitosan can learn from body fat to 10-12 times its molecular weight. Chitosan adsorbs fat in the stomach before he begins to digest, lowering cholesterol, "bad" and increasing cholesterol "useful". Research at the University of Helsinki showed that in some patients, weight loss was 6-8% for four weeks. Diets containing chitosan reduce the risk of heart disease, hypertension, diseases associated with disturbance of the endocrine system.

Found that chitosan captures and destroys bacteria and removes them from the intestines, thereby preventing their spread through the body and the occurrence of various diseases. The proposed tool, called "Hitoha", is a tablet formulation containing a hodgepodge Holloway and chitosan. Present in phitochitodes chitosan not only prolongs the effect of drug R is relevant, anti-inflammatory, antioxidant action and the ability to destroy a dense formation of toxic fractions of vegetable protein in the epithelium of the intestine, i.e. to eliminate the causes of disease.

The preparation of Salsola Collina herb with chitosan retains all the healing properties of Salsola Collina, acquiring additional therapeutic properties: improves heart, normalizes the total and coronary circulation, lowers cholesterol and blood sugar, has analgesic properties, normalizes heart rhythm, reduce the phenomenon of swelling, prevents the formation of blood clots, corrects metabolism and sedative properties.

When creating "Hitohira" chitosan combined with the hodgepodge Holloway because were detected unexpected properties.

It is known that in humans there are no active enzymes that destroy glycosidic bond of chitosan and chitin, so it is poorly absorbed by the body, not more than 12.5% of the input quantity is water-soluble low-molecular fractions of chitosan. High molecular weight fractions /s MM= 20000-120000/ almost insoluble in water, but they mostly have unique properties: bacteriostatic, is S="ptx2">

It is observed that some substances contribute to the translation of oligomeric chitosan intake of water-soluble fractions. This saliva lysozyme, collagenase and lectins of plant origin is a complex metal-containing protein complexes capable of performing the role of chitinases. Lectins are found in many plants, but especially high content in plants grown on the silica /Western Ukraine, Siberia, Moldova, including the hodgepodge Holloway. Lectins are involved in the degradation of chitosan, which leads to better absorption-penetration into the blood and lymph and increases the bioavailability of the whole preparation. The presence in the preparation of oligomeric water-soluble intake fractions of chitosan performs a significant role in immunostimuliruyushhim action, strengthens and improves the condition of the joints and skeletal system, increasing antioxidant effect.

On the other hand, chitosan enhances the healing properties of Salsola Collina - unique properties of plants, providing prolonged action of biologically active substances.

Preclinical tests were carried out on the basis of medical diagnostic center of JSC "Sovcomflot" in the period of autumn and winter flu epidemic and obilicev.

50 people took the drug "Hitoha" in table 2. 3 times a day before meals for 18 days.

37 people took placebo for 18 days.

At the time of admission "hitohira" no one from the main group with the flu or colds not ill. In the control group, 18 people are sick - they were on medication.

From the main group the majority of patients noted significant improvement in General condition, increase efficiency, improve sleep.

6 men said the best tolerance of alcohol, no hangover.

The most noted improvement in the digestive tract. Patients suffering from allergic reaction during administration of the drug to feel comfortable and refrain from taking antihistamines.

Thus, the tests showed that "Hitoha" undoubtedly possesses curative properties: enhances immunity, improves gastrointestinal function, has anti-allergic properties.

In addition, the tool "Hitoha" was used in the treatment of several diseases.

Example 1. Patient Glagoleva N. In., 54 years.

The Diagnosis Of Arthritis. Treatment within 30 days, 3 times a day after eating sposobnosti, x-ray images before and after administration of the means showed a marked change in the structure of the articular surface. Biochemical analyses in norm.

Example 2. Agapov K. A., 29 years.

Diagnosis: Erosive gastritis, duodenitis. Thirty days the patient during the meal took 2 tablets 3 times a day. At the end of treatment, there were no complaints during the whole period of the reception means. No pain, irritability. Biochemical analysis of normal.

Example 3. Patient Dashko E. C., 43 years.

Diagnosis: Hypertension, hypothyroidism. Assigned to 3 tablets, 3 times a day for 30 days while eating means "Hitoha". The treatment results in marked decrease in the frequency of headaches (almost daily to 1 times in 7-10 days), improving sleep, reducing anxiety, improving skin condition.

Example 4. Sick Detkov Etc., 18.

The diagnosis of Dyskinesia of the gallbladder, gastritis. Took 2 tablets, 3 times a day during meals means "Hitoha" within 30 days. The results of biochemical analysis of blood after treatment is normal, marked reduction in pain in the right hypochondrium, no nausea, improvement of General condition, ">

Diagnosis: Erosive gastritis, calculous cholecystitis. 2 tablets 3 times a day during meals took means "Hitoha" 30 days. The treatment results in marked improvement in overall health, increased gastric tone, the absence of a familiar pain after eating and hard work, improvement of sleep and lack of fatigue and exhaustion after work. Biochemical homeostasis in normal.

Example 6. Patient Burganov A. N., 30.

Diagnosis: Catarrhal gastritis, sciatica. Within 30 days 3 times a day during meals took "Hitoha" 2 tablets. As a result of treatment the patient notes the increase vitality, improve sleep, appetite, increase mobility, health, reducing pain in the joints after a meal.

Example 7. Patient Vakulenko O. A., 27 years.

The diagnosis of Dyskinesia of the gallbladder, helminthic invasion. 2 tablets 3 times a day during meal within 30 days of taking the remedy "Hitoha". As a result of treatment, the patient noted improvement in General condition on the 5th day of receiving funds. Increased efficiency, normalized condition of the nervous system, decrease irritability, calm in conflict situations.

1. The agent with immunomodulatory and anti-allergic effect, characterized by the fact that it is made in pill form and contains grass powder Salsola Collina, chitosan, filler and vitamin C in the following ratio of ingredients, mg:

Grass powder Salsola Collina - 200

Chitosan - 45

Vitamin C - 10

Filler - 45

2. Means under item 1, characterized in that the filler it contains microcrystalline cellulose, calcium stearate, and starch.

3. The agent with immunomodulatory and anti-allergic effect, characterized by the fact that it is made in pill form and contains dry extract of Salsola Collina, chitosan, filler and vitamin C in the following ratio of ingredients, in mg:

Dry extract of Salsola Collina - 25

Chitosan - 25

Vitamin C - 10

Filler - 240

4. Means on p. 3, characterized in that the filler it with the

 

Same patents:

The invention relates to the field of medicine and relates to a combined anti-tuberculosis drugs, containing as active substances isoniazid and pyrazinamide or ethambutol hydrochloride, and as auxiliary substances - calcium phosphate dihydrate and/or starch, polyvinylpyrrolidone and/or talc, stearic acid or its salts, and method of its production by mixing the active ingredients with calcium phosphate dihydrate and/or starch, moistening the mixture with an aqueous solution of starch or polyvinylpyrrolidone with subsequent granulation, drying and dusting

The invention relates to the production of compressed forms in the food and pharmaceutical industries
The invention relates to biotechnology, in particular to the manufacture of biologics-probiotics

The invention relates to medicine, specifically to medicines with antimicrobial activity

The invention relates to medicine and relates to oral pharmaceutical dosage forms containing sensitive to acid proton pump inhibitor and one or more antacid substances or alginate in a fixed structure in which the proton pump inhibitor is protected by a layer Intercollege coating and optionally a separating layer between proton pump inhibitor and intersolubility coating, the fixed part has the form of a multilayer tablets, sachets or complex tablet dosage forms

The invention relates to medicine, specifically to drug, possess antiulcer action
The invention relates to medicine and relates to a composition having a General tonic, stimulant and radioprotective action
The invention relates to the pharmacy, to homogeneous prefarbly containing steroids, for the manufacture of pharmaceutical preparations with a content of from 0.01 to 1% steroid weight

The invention relates to the field of pharmacy
The invention relates to medicine and can be used for treatment of peptic ulcer of the duodenum
The invention relates to medicine
The invention relates to oil, food, medical and cosmetic industries
The invention relates to medicine, namely to herbal medicines for the treatment of morning sickness in the early stages of pregnancy
The invention relates to medicine, namely to addiction, and can be used in the treatment of alcoholism and addiction, and rehabilitation therapy body functions

The invention relates to the field of veterinary medicine, in particular for the prophylaxis and treatment of stress animals
The invention relates to the field of medicine and is concerned medicines based on plant materials
The invention relates to the food, cosmetics and medical industry

The invention relates to medicine, in particular to Infectology, and for the treatment of various diseases in the etiopathogenesis involving infection
Up!