The method of complex treatment of glaucoma

 

(57) Abstract:

The invention relates to medicine, ophthalmology, to methods for treating glaucoma. Enter monomineral selenium, leaf Ginkgo-Biloba", take foods rich in selenium excreted toxic metal aluminum drug "BIOPROTECT" in patients receiving therapeutic doses of vitamin a, C, E, bee pollen and routine. This method can improve therapeutic effect, improve microcirculation vascular bed of the eye, to achieve long-term remission of the disease and the condition has stabilized.

The present invention relates to medicine, namely to ophthalmology, and can be used in the treatment and prevention of various types of glaucoma (primary, advanced and severe).

The urgency of the invention is defined by the fact that glaucoma is one of the most intractable problems of ophthalmology: frequency of blindness from glaucoma remains relatively high and is at a level according to who, to 14.1%.

In the General structure of ocular pathology glaucoma is 6%.

All known methods of treatment characterized by a significant number of the drugs used, their periodic for what about the many cases only a combination of conservative and surgical treatment methods allow you to save the eyesight of a patient with glaucoma.

There is a method of treatment of glaucoma (Kurilin ie, Complex treatment of patients with primary glaucoma. The dissertation on competition of a scientific degree of Kida. the honey. Sciences. Kiev red banner of labor medical Institute. Akademika bohomoltsia, 1971), in which patients under the supervision of the daily curve of intraocular pressure and heart appoint an individual scheme of mytiki: pilocarpine in combination with ephedrine, proserin or more potent drugs such as Armin, phosphocol, piropos. After production of mitotic mode attach functional therapy: KL ACC, privateline procaine blockade, Ca - collars, Ca - electropores, vitamins of group B, bromides, a complex of physical exercises.

Cons: the complexity of the method, the duration of treatment is up to several months and the lack of efficiency (up to 65%).

As a prototype adopted a method of treating patients with glaucoma (Stukalov S. E., Zakharov, I. A. Application of immunocorrective drugs in treatment of patients with primary open-angle glaucoma. Ophthalmological journal, No. 7, S. 402-403, Izd-vo "dorow,I" Odessa, 1987, ISS - 0030-0675), in which the complex of the funds used nuclear sodium, decaris, timely, Essentiale Forte. When topically applied cholinomimetic agents, anticholinesterase and sympathetic funds.

Nuclear sodium is administered 0,5x3 times a day. Essentiale Forte 2 capsules x 3 times a day for 2 weeks.

Cons: unreliable in increasing treatment effect compared with traditional methods, the duration of treatment, the overall positive effect up to 65-70%, nespecificnomu impact on the underlying disease is glaucoma.

The main problem solved in the development of the proposed method of treatment of glaucoma, is to increase the efficiency of treatment of patients up to 90% or more.

The essence of the proposed method is that in the complex treatment of patients with glaucoma include replenishing the body's deficiency of the trace element selenium excretion of excess toxic metal is aluminum, the accumulation of which is a contributory factor in the occurrence of glaucoma, the normalization of the Genesis of the vascular bed. Given that glaucoma is not a local disease, and certain violations of the whole body, while the patient is prescribed medical food, including products enriched with selenium, and vitamin complex, including the leaves of the Ginkgo-Biloba.

The method is as follows.

To compensate for the deficiency of selenium in the medical complex includes monomineral selenium at a dose of 50-100 mg per day in combination with vitamin E that provides synergies. In addition at the same time the patient a therapeutic combination of foods fortified or containing the trace element selenium: onion, garlic, black bread, mushrooms, bacon, meat, sea-buckthorn berries, corn, sunflower seeds, cereal seeds legumes, sea food. After reaching stabilization (2-3 weeks), patients are switched to receive supportive and preventive care complex that includes the same drugs, the dosage is reduced twice.

The rationale for this tactic is that the basic premise of glaucoma is a selenium deficiency in the body.

For removal of toxic metal is aluminum, the accumulation of which is a contributory factor in the occurrence of glaucoma, prescribe medication "BIOPROTECT", which is included in the combination of herbs gently detoxifying the body, activates the metabolism, regulates the regeneration of the protective systems of the body, helps to restore the nervous and hematopoietic systems. Bioproductive factor in the proposed method provided by the use of the extract from the leaves of Ginkgo-Biloba, containing 40 ingredients, active range which effectively has a positive effect on the microcirculation of capillary and venous channel, oxygen supply, and normalizes the level of ATP, increases the resistance of cells to the eye tissue to hypoxia. Leaf extract Ginkgo-Biloba administered in the dose of 360 mcg x 3 times a day for 2 months.

In addition to the mandatory complex used to treat drugs injected vitamins A, E, 25-50 thousand units, vitamins C, 6-12 mg, bee pollen, 0.25 - 0.5 tsp and rutin, 50-100 mg as vitamin E injected proliferation, in conventional doses.

The proposed method has been tested since 1997, 650 patients, including 175 people with the initial stage, 410 - developed and 65 - severe.

The technical result of the testing method were: improvement of visual functions and stabilization of the level of intraocular pressure is achieved within the following limits: initial stage - 96%, advanced - 88% and severe - 62%.

In 29 patients developed glaucoma treatment outcomes reduced mode instillation of anti-hypertensive drugs, and 11 patients from the group of severe glaucoma cleared indications for operative interfere visual functions and intraocular pressure, the marked improvement in the General condition of all patients (including blood, heart, brain and other).

Long-term follow up of patients after discharge ranged from 6 months to 2.5 years. The assessment of their condition was carried out by traditional methods and the study of the content of trace element imbalance in the patient's body.

The patients had no complaints, it was noted stabilization of glaucoma process and visual functions, and in some cases its gradual improvement. The marked deterioration in those cases when patients do not comply with doctor's prescriptions.

The reproducibility of the method is not in doubt and has virtually no contraindications, as it considers the individuality of each case.

Inventive step is obvious, since up to the present time experts have not been used in practical ophthalmology.

Example: Patient A., 1924 birth, history N 5692, received 1.07.1998, diagnosed with open-angle IIIC glaucoma (uncompensated) of the right eye, open-IIB (subcompensated) glaucoma of the left eye.

Notes a gradual reduction of vision in the next 5 years, Bo is right), brow, forehead and nape of the neck, aggravated by emotional stress, after a bad night's sleep or if there is a sudden change of weather. Feels constant "weight" in the eyes, more on the right. Wearing presbyopic glasses 28 years. 20 days ago found that the right eye sharply reduced vision.

Objective data: the visual acuity of the right eye of 0.01 n/a, the left eye of 0.1 s (+)4.5 = 0,8.

Right eye: mild congestive injection of the conjunctiva of the eyeball, swelling of the epithelium and endothelium of the cornea, light, front camera is slightly less than the average, the moisture transparent, the pattern of the iris is smoothed in places atrophic, the pupil is round, slightly expanded sluggishly reacting to light, the angle of the anterior chamber (gonioscopy) is open, trabecular area sclerotic (fibrous), there are areas of pigmentation. When biomicroscopy - discovered complicated and initial sydneypass opacities in the lens. The optic disc is pale, clear boundaries, glaucomatous excavation pronounced shift of the vascular bundle to the nose. Intraocular pressure at admission 39 mm Hg, field of view concentrically narrowed at 35-40 degrees.

Anterior segment of the left eye is almost not changed - there is a slight smoothness of figure Radoi is less than clear, there is a light subatrophy physiological excavation and a small shift of the vascular bundle to the nose. Intraocular pressure at admission 29 mm Hg.

Two years ago the patient was treated: trental parabulbarno 0.5 N 10, taufon 4% under the conjunctiva 0.3, diacarb 1 tablet 1 time in three days, sinocarotid blockade of 2% lidocaine instillation of ocupress 0,5% x 3 times, fotil x 1 time a day in the right eye and the left eye ocupress 0.5% of 2 times. The results of the treatment of weakly positive, achieved subcompensated. Surgical treatment the patient is contraindicated for General condition. The patient is examined for trace elements by atomic emission spectrometry with inductively coupled argon plasma (biosubstrate - hair). Detected trace element imbalance: selenium deficiency, the content of which is reduced in 10 times the norm, and the content of aluminum of 18.2 ág/g more than normal.

Excessive accumulation of aluminium caused a concomitant vascular diseases of the brain, increased total peripheral vascular resistance.

A patient with 15.07.98 assigned monomineral selenium 100 mcg per day in conjunction with vitamin E in common is 0 mg/day), BIOPROTECT - 1 teaspoon x 2 times a day, memaid-Ginkgo-Biloba. In addition, the patient is recommended a diet with a high content of selenium, i.e., with mainly products onion, garlic, black bread, mushrooms, sea buckthorn and other, excluding consumption of canned goods, milk, cheese, smoked meat. With the re-examination after 3 months the content of aluminium in normal, selenium is reduced 3 times. The treatment was carried out on the background of the application hypotensive drops in the form of instillation several times a day, the mode of which is gradually decreased until the preventive mode 1 time per day.

In the intraocular pressure decreased to normal values, improved visual function - field of vision expanded in his right eye at 25 degrees, visual acuity rose in his right eye to 0.1, and the left eye to 0.9. When using the method allows to significantly improve the effectiveness of treatment, to ensure high performance and efficiency in achieving results, improving the reliability of the survey.

The high importance of the method is the individual approach to each patient and their use for the prevention of glaucoma.

Way to the audiusa fact, making up for the deficiency of selenium by taking monomineral selenium and foods rich in selenium, simultaneously from the body remove toxic metal aluminum drug "BIOPROTECT" and improves microcirculation and venous channels of the eye by administering to the organism of leaf extract Ginkgo-Biloba.

 

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