The treatment for viral hepatitis b and c and the method of its treatment

 

(57) Abstract:

The invention relates to medicine, specifically to the creation of a plant for the treatment of viral hepatitis B and C and the method of its treatment. The essence of the invention lies in the fact that the proposed remedy in the form of a collection containing lectins and includes corn silk, leaves of lemon balm, peppermint, sage, herbs Catnip cat, mnogogolosnyy wrinkled and marigold flowers at a ratio of 7 : 3 : 3 : 1 : 5 : 7 : 7 respectively. Proposed method of treatment using the above collection in the form of infusion, the treatment from 2 to 6 months. The proposed method of treatment with the specified tool allows you to effectively work on the cause of the disease, to eliminate the pathological symptoms of the disease, to neutralize HyperTerminal and increase remission of the disease. 2 S. p. f-crystals, 2 tab.

The invention relates to the field of medicine and for the creation of tools for the treatment of viral hepatitis B and C and the method of its treatment with the use of natural raw materials.

Know the use for the treatment of hepatitis B and C vitamins, immunomodulators, and anti-viral drugs (recombinant alpha - intima three times a week with ribavirin for 6 months it has an effective influence when had transient improvement interferonoterapii (8). However, when using expensive interferon-alpha therapeutic efficacy of the drug is aimed at increasing the resistance of the body of viral hepatitis and has virtually no effect on the cytolysis of cells of the liver and does not eliminate the phenomenon giperfermentemii that contribute to the chronicity of the process (5).

It is known for the treatment of viral hepatitis B and C in the form of herbal collection "Politicka", consisting of immortelle, tansy, licorice, peppermint, nettle, rosehip cinnamon. The drug is administered 1 teaspoon of powder per 30 minutes before meals 3 to 4 times a day. The mechanism of action is associated with the presence of phenolic compounds, which are universal stabilizers of biological membranes. Lowering the intensity of lipid peroxidation in liver tissue, they inhibit exudative phase of the inflammatory response and stimulate proliferative processes. On the other hand, they have holetsaticescoy activity, reduce the tone of smooth muscles, resulting in reduction of cholestasis (7).

The disadvantage of this method is low antiviral activity at the expense of mint leaves, which contain a small amount of pectin, and hypermedia is the creation of a group of inventions United by a single inventive concept with the aim of increasing the effectiveness of therapy due to etiotropic treatment, expanding the range of herbal medicines for the treatment of viral hepatitis B and C.

This problem is solved using the creation of phyto compositions of native plant materials containing significant amounts of lectins - natural glycoprotein, stimulating the synthesis of DNA and RNA in blood lymphocytes. They stimulate the growth and division of T - and B - lymphocytes, increase concentrationCGMP in the cell and the permeability for ions K=and Ca++increase membrane fluidity, increasing the transport of metabolites (carbohydrates, amino acids, nucleotides), the change in the synthesis of cytoplasmic and membrane proteins (4).

Lectins induce the formation of lymphokines - regulators of immunological reactions, inhibit the migration of macrophages, showing cytotoxic effect and suppressing the reaction of blast transformation. Antitumor activity of lectins is by blocking receptors of tumor cells and inhibits their migration. They have the ability to activate lymphocytes, fibroblasts, hepatocytes, stimulating processes turnip is irout tissue immunity, have antiviral, antimicrobial activity, increasing the phagocytic activity of leukocytes, i.e., have certain hepato-, cyto - and radioprotective properties that defines them as prophylactic agents in high-risk objects.

Thanks to the efforts of scientists of Ukraine (E. L. Golynskaya), Belarus (I. E. Boreco, C. M. Rimsha), Russia (C. F. Korsun, L. C. Pogorelskiy), was created and studied pectinesterase collection containing seven herbs - sage, megacolony, mint, lemon balm, Catnip, corn silk and calendula. Clinical and experimental studies showed high antiviral activity collection against pathogens herpes, influenza, VAL) ECHO-6 and other viral infections, including acyclovir and amantadinebuy strains (6).

To accomplish the objectives of the proposed means of plant origin in the form of creation of phyto compositions containing lectins: corn silk, leaves of lemon balm, peppermint leaves, sage leaves medicinal, herb Catnip cat, grass mnogogolosnyy wrinkled, flowers of calendula in the following ratio 7:3:3:1:5:7:7 respectively.

Also we propose a method for the treatment VII before eating, in the following days with 70 ml 3 times a day, a course of treatment from 2 to 6 months.

The basic medicinal plants include the following affecting certain symptoms of the disease and is used in the treatment of hepatitis.

Corn silk (Stigmatis Zeae maydis) contain saponins, resins, sitosterol, lectins, ascorbic acid (11). Preparations of corn silks, increase the formation of peptides of the gastrointestinal tract, which have a stimulating effect on the hypothalamic-pituitary activity (10). They are used as a choleretic, diuretic and styptic agent.

Melissa (Melissa officinalis) contains lectins, vitamins, tannins, coumarins, flavonoids, phenolic acid and ursolic acid. Has antispasmodic, analgesic, tonic action (10).

Peppermint (Mentha piperita) contains lectins, up to 4% essential oil, mainly monocyclic terpenoids (11) mint Leaves are used as a carminative agent, an emetic, antispasmodic, anti-scorbutic, and antiseptic.

Sage (Salvia officinalis) contains up to 2.5% by essential oils, lectins, which prowl the recommendation, reduce the high permeability of the blood-tissue interfaces barrier, prevent the action of hyaluronidase (1).

Catnip cat (Nepeta cataria) contains up to 3% of iridoids (nepetalactone), saponins, lectins, coumarins. Proven therapeutic effect of water extraction for colds (11). Exhibits antipyretic, diaphoretic, softening tool and is used for colds, whooping cough, any hyperthermia, inflammatory diseases, tuberculosis, pneumonia (1). The plant has long been used in Europe and the East as spicy, delicious, restorative tool. Restorative effect of drugs Catnip shown in the clinic (9).

Megacolony (lefant) wrinkled contains lectins (4), essential oil of complex composition. It is noted that megacolony has antibacterial, tonic properties, regulates metabolism and blood pressure (12). The most common plant used as a spice to second course.

Calendula officinalis (Calendula officinalis) contains carotenoids, lectins, flavonoids, volatile oil, resin, coumarins and organic acids (11). Preparations of calendula are wound healing, diuretic, antibacterial, antiviral (2), protivovesa what I viral diseases of the skin (warts, condylomas).

The collection is prepared in the form of infusion at the rate of 2 g of finely crushed dry ingredients 200 ml of boiling water and take 50 ml 3 times a day for 5 days before eating. In the following days of receiving the dose is increased to 70 ml 3 times a day. The basic requirement when using infusion of the proposed creation of phyto compositions is an exception sweetening with sugar, honey and other products, otherwise occurs inactivation of lectins. The treatment is 2-3-6 months.

The invention is illustrated by the following examples:

Example 1. Patient C., age 17, resident of p. Forest Pushkin district, Moscow region. Hurts hepatitis B and C since 1997, was Treated in hospital district hospital, the arts and in the children's Department MONICA, where he conducted therapy with vitamins, lacenterra, Amiksin. However, the improvement was short-lived. In March 1999, noted the appearance of pain in the right hypochondrium, jaundice of the skin and mucous membranes. Was re-admitted to the district hospital at the place of residence, where he received gemodez, Essentiale, multivitamin. Asked for a consultation 4.09.1999, with complaints of weakness, pale skin, weakness. Blood bilirubin total is 27.2 mmol/l, direct the fair treatment within 2 months. When re-examination of the complaint of recurrent pain in the right hypochondrium saved. Paleness of skin and mucous membranes, weakness, yellowing of the sclera disappeared. Blood tests - HbB and HbS - antigen negative. Blood biochemical parameters: total bilirubin to 12.0 mmol/l, associated to 3 mmol/l, ALT - 35 units/l; AST - 40 units/liter Is within 10 months follow-up. The condition is not getting worse.

Example 2. Patient L., aged 26, is not working. A resident of Moscow. Sick With hepatitis C about 1 year. The cause of the disease does not name. Allegedly using drugs. Was treated in the infectious diseases Department of the hospital. S. P. Botkin within 1.5 months without much improvement. Turning 14.11.1997, complaining of nausea, bitter taste in the morning in the mouth, weakness, enlargement of liver 4.5 cm below the edge of the costal arch; on ultrasound diffuse changes of the liver with signs of cirrhosis. The research results are summarized in table. 1.

The patient was assigned to the claimed method of treatment. therapy was about 5 months. Tolerability was good. No complications from therapy were observed. The patient is on maintenance therapy, which is the OS the program was awarded the correction not only biochemical, but serological blood counts, indicating a high efficacy and a favorable prognosis.

Example 3. Patient A., 13 years old, a resident of Moscow. Focused on advice from the pediatric clinic, due to lack of treatment efficacy. It hurts for about 3 years hepatitis C. was Treated in hepatocentre, infectious diseases hospital No. 1, to the infectious hospital. S. P. Botkin, where treatment was conducted lomustin, Essentiale, holenzim, tykveol, hofitol and other laboratory Findings are shown in table. 2.

Patient A. received within 4 months of the claimed method of treatment. Tolerability was good. Biochemical parameters and General condition of the patient (disappeared nausea, bitter taste in the mouth, recurrent pain in the right hypochondrium) has improved. However, serological indicators remained unchanged. The treatment continues. The patient is on a dynamic outpatient observation and treatment.

The proposed method of treatment with the specified tool allows you to effectively work on the cause of the disease, to eliminate the pathological symptoms of the disease, to neutralize HyperTerminal and increase remission of the disease. It is possible for the conservative, the preamble is it duodenitis, cholecystitis, cirrhosis, angiocholitis, gall-stone disease etc ). The method is simple and economical to use.

Literature

1. Barnaul O. D. Herbal medicine pulmonary tuberculosis. - SPb., 1999.

2. Bogdanova N. With. et al., The study of the antiviral properties of calendula // Pharmacol. and toxicol., 1979, T. 33, N 3. - S. 349 - 355.

3. Vechkanov S. A. et al. Antiviral activity of the essential oil of E. viminalis and some hardy eucalyptus // Pharmacol. and toxicol., 1973. So 36. N 3 - N-339-341.

4. Golynskaya E. L. Lectins as operating beginnings of some medicinal plants // proc. Dokl. the first REP. proc. over the honey. botany. - Kiev, 1984. - S. 104-105.

5. Pogorelsky L. C., Korsun C. F. Zhuravlev, Y. S., Turanov M. H. Herbal medicine in the infectious diseases practice. - M., 1998.

6. Rimsha C. M. Inhibitor of viruses. Patent Of The Republic Of Belarus N 2942. - 1998.

7. Turganov M. H. et al., Phyto - and laser therapy in complex treatment of viral hepatitis //proc. Dokl. 5 ROS. Congress of infectiologists. - M., 1998. - S. 390-391.

8. Tsurikova N. N. et al. The results of treatment of recombinant interferon in patients with acute hepatitis C // ibid. - S. 341 - 342.

9. Copic C. I. et al., Decora.

11. Encyclopedic dictionary of medicinal plants and animal products /Ed. by G. P. Yakovlev. - SPb., 1999.

12. Encyclopedia of herbal teas /Comp. : A. Y. Nesterov and others - M., 1997.

1. The treatment for viral hepatitis B and C, containing medicinal plants, characterized in that it includes the infusion of medicinal plants containing lectins: corn silk, leaves of lemon balm, peppermint, sage, herbs Catnip cat, mnogogolosnyy martinstag and flowers of calendula with a ratio of 7:3:3:1:5:7:7 respectively.

2. The method of treatment of viral hepatitis B and C by ingestion of medicinal plants, characterized in that you accept the infusion of medicinal plants containing lectins and includes corn silk, leaves of lemon balm, peppermint, sage, herbs Catnip cat, mnogogolosnyy martinstag and marigold flowers at a ratio of 7:3:3:1:5:7:7 accordingly, while the first three days of 50 ml 3 times daily before meals, in the following days with 70 ml 3 times a day, a course of treatment from 2 to 6 months.

 

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FIELD: medicine, cardiology, phytotherapy, pharmacy.

SUBSTANCE: invention relates to the field in development of an agent of vegetable origin used for improvement of the functional state and prophylaxis of organic alterations in cardiovascular system, in particular, atherosclerosis. The biologically active supplement used for prophylaxis of cardiovascular diseases, in particular, atherosclerosis comprises clover dry extract, haw-thorn flowers powder, ascorbic and nicotinic acids, and accessory substances taken in the definite ratio. The biologically active supplement is made in the form of tablet or capsule. No adverse responses observed in intake of the supplement. The blood cholesterol level was reduced to the normal value in 68% of patients and reducing morbidity with acute respiratory-viral infections has been noticed. In patients with ischemic heart disease with cholesterolemia the improvement of the state is noted on the background of conventional therapy: the moderate reducing the arterial pressure value in its elevation, improved in the state of health, enhanced working capacity, reduced retrosternal pains, ear noise, vertigo, headache.

EFFECT: valuable medicinal properties of supplement.

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