For the treatment of psoriasis (options) and the method of its treatment

 

(57) Abstract:

The invention relates to medicine, namely to create tools for the treatment of skin diseases, particularly psoriasis and how to treat it. The proposed tool in the form of extracts of medicinal plants and ointment for overlay applications on the affected areas, including plant material. Also we propose a method for the treatment of psoriasis using tincture and ointment plant-based and additional intake of tincture of a peony in the amount of 1 ml in 50 ml of water in the evening. In all cases, the treatment proposed by the tool leads to a stable therapeutic effect and increase magnetizing period of the disease. 3 S. and 1 C.p. f-crystals.

The invention relates to the field of medicine and for the creation of tools for the treatment of skin diseases, particularly psoriasis and how to treat it.

It is known the use of biologically active substances and applied on the lesions healing ointments on the background diet and normalization of the mode of work and rest (1).

However, the known means and method is not effective enough and the possible recurrence of the disease.

The objective of the invention is to improve the efficiency and increase miracidium is a single inventive concept.

The essence of the invention lies in the fact that the proposed infusion of medicinal plants (wt.%).

The roots of aralia Manchu - 5-6

Hawthorn blood-red - 20 - 23

The fruits of a mountain ash ordinary - 20 - 23

The fruits of black chokeberry - 18-20

Hips may - Rest

Also proposed ointment containing, in wt.%:

An aqueous extract of the fungus - 5-6

40% alcohol extract of celandine - 3 - 5

Salicylic acid - 2 - 3

Vaseline - 42-45

Lanolin - 42-45

A method for treatment of psoriasis.

Within 4 - 6 weeks during the stationary phase of psoriasis twice daily rash apply a thin layer of ointment, consisting of an extract of birch fungus, celandine, salicylic acid in petrolatum lanolin base, and carefully rubbing. In addition, daily morning and afternoon during the whole period of treatment inside are the infusion of herbs 100 ml 70 ml containing rosehips, hawthorn, mountain ash ordinary and black, the roots of aralia, for 20 minutes before eating. In the evening the patient receives 1 ml of tincture of a peony in 50 ml of water 1 hour before bedtime. For children the dose of herbal medicines is 2 drops for each year of life for one admission with required primal boiling water.

Aqueous extract of birch fungus is used as an official drug befungin permitted as an internal tool for the treatment of gastroenterological patients (12). Celandine extract is prepared from the dry grass at 40% alcohol in a ratio of 1:4 according GF 10 edition (11).

In the treatment of psoriasis follow a diet and regime. From the power to exclude fatty foods with a variety of dishes and an abundance of vitamins vegetable origin. Restrict the amount of sugar, spicy foods and seasonings.

Treatment should not be initiated during exacerbation of the disease.

The disappearance of the disease occurs in 30 to 40 days after the commencement of the proceedings.

The basic medicinal plants within the infusion and topical dosage form, include the following affecting certain symptoms of the disease and is used in the treatment of psoriasis.

Birch mushroom, chaga (Inonotus obliquus) is a parasitic fungus of the family tree. It contains water-soluble pigment complex, which has an aromatic nature and is based on the type of humic acids. The curative effect of the fungus to a certain extent due to the presence of steroid compounds lanosterol is a high-polymeric aromatic substance the product of the oxidation of phenolic substances under the influence of fungal laccase and their subsequent polymerization. Stimulatory effects of the fungus on the Central and humoral systems of the body and the metabolism. They increase the body's resistance and promote the formation of compensatory-adaptive mechanisms (5). Chaga is used in gastroenterology, Oncology, dermatology (6). However, there is no information about the use of fungus in the external treatment of psoriasis as mono - or combined preparations.

Greater celandine (Chelidonium majus) is a perennial herbaceous plant of the poppy family. He refers to alkalinebatteries plants (chelidonine, oxyhalides, sanguinarine, chelerythrine, homochelidonine, chelirubine, coptisine, spartein and others). Celandine drugs delay the growth of malignant tumors, have proteoliticeski, antiviral, antispasmodic, local anesthetic, reparative, anti-inflammatory, bactericidal, choleretic, wound-healing effect (7). More commonly used aqueous extract of the plant (7), however, the alkaloids insufficient extracted from plant raw water izvlekateljami, and slideline-reduction processes in the organism, involved in the oxidative deamination of aromatic amino acids, activate a number of enzyme systems, stabilize the adrenaline and other catecholamines that stimulate the body's resistance to the harmful effects of the external environment (6). The presence in the fruit of vitamins B, E and carotene gives the herbal remedies wild rose missing links stimulatory effect on anaerobic decarboxylation of pyruvic acid with subsequent activation of enzyme systems. Fruits also contribute to the regeneration of tissues, the synthesis of hormones beneficial effect on carbohydrate metabolism and vascular permeability (2).

Hawthorn fruits (Cratagus sanguinea) due to the presence of a complex of flavonoids, minerals, and oksikorichnye acids exert a hypocholesterolemic effect, reducing the level of cholesterol in the blood and increasing the number of lecithin (10), which is important in the treatment of psoriasis. Has significant antiviral effect of hawthorn against herpes virus (9), given the retroviral nature of psoriatic disease (6).

The fruits of mountain ash ordinary (Sorbus aucuparia) contain carotenoids, flavonoids, vitamins and take a multivitamin and anti-de is the complex have hepatosteatosis, kapillyaroukreplyayushim and antiviral action (6) that can be recommended in the treatment of psoriasis.

The Manchurian aralia (Aralia manshurica) contains triterpene saponins - arylazide, which increase the stability of the major physiological systems of the body to the adverse effects that can create in the body condition of non-specific increased resistance, regulate the course of a stressful situation (2), which determines the need for the use of its drugs in the treatment of patients with psoriasis (6).

The invention is illustrated by the following examples.

Example 1. Patient P., 46 years old, chief accountant of one of the organizations of Moscow. He complained of pain in the hip, elbow and ankle joints, multiple psoriatic lesions in the skin of the trunk and extremities. Sore psoriasis 1.5 years. Stay in the South significantly reduces the number of acne, but after 2 weeks they come back again. Was treated in LLC "Venus" calcium, aevit and cream. Took biologically active additives to food companies, "Dr. Nona", but the improvement was not.

Locally: on the skin of the trunk and limbs are multiple rounded infiltra form. Psoriatic arthritis. Assigned to the proposed treatment in the treatment of 38 days. Effects of treatment - pain in the joints decreased, psoriatic lesions apostiles, their number has decreased significantly. In the centre of some of the plaques, the appearance of the skin pink color with no signs of lamellar peeling. Fresh rash no. Significant improvement of the skin. The observation lasted for 8 months. Relapse was not.

Example 2. Patient B., 21, the driver of one of the automobile companies, Korolev, Moscow region. Turned 14.10.1998, with complaints of multiple psoriatic plaques on the scalp, elbows and knees. Ill 7 years. Was treated repeatedly and by different means: Skin cap, psoriasin, radevit, psoralen, psorkutan and other Effect comes through the month, but after 2 to 4 weeks again with recurrence of the disease. He had hepatitis A, acute gastritis. Obesity 1 tbsp. Topically on the scalp multiple infiltrated rounded plaques with abundant lamellar desquamation. Some of them are from under the edge of the hairline. On the elbows, knees rounded plaque 3 X 5 cm with a generous plate cellulosine plaques on the occipital region and right knee. Observed in 18 months. Disease recurrence occurred in 11 months, but when re-treatment after 3 weeks, the rash disappeared.

Is medical supervision. During the observation period lost 7.5 kg

In all cases, the treatment of the specified tool leads to a stable therapeutic effect.

LITERATURE

1. Korsun C. F. Treatment and rehabilitation of patients with psoriasis. - Minsk: 1991. - S. 10-29.

2. Sokolov, S. I. , zamotaev I. P. Handbook of medicinal plants (Phytotherapy). - M., 1990.

3. Doychev E. A., Bystrov Century. N. Psoriasis treatment drugs mushroom chaga" News. dermatol., 1973. - N 5. - S. 79 - 83.

4. Corti A. N., Lasewa A. P., Dontsov, And trace elements in clinical lighting. Sverdlovsk, 1969.

5. Balitsky K. P., Vorontsov A. P. Medicinal plants and cancer. - Kiev, 1972. - 375 C.

6. Korsun C. F. Herbal medicine psoriasis. - Minsk: 1993. - S. 117 - 125.

7. Stanari M. P. About lcould properties cistotu svechina. - Republican, 1966.

8. The Potopalsky A. I., Potopalsky A. J. Treatment of psoriasis drugs celandine // Doctor. case, 1964. - N 8. - S. 129-130.

9. Modern herbal medicine / Ed. by C. Petkov. Sofia, 1988. - 504 S.

10. Tours what I Pharmacopoeia of the USSR, X edition. - M., 1989.

12. Mashkovsky M. D. Medicines. Ed. 14-E. - M., 2000.

1. For the treatment of psoriasis, containing extracts of medicinal plants, characterized in that it is an infusion of medicinal plants, including the roots of the Manchurian aralia, hawthorn blood-red, Rowan ordinary, black chokeberry and hips may in the following ratio, wt%:

The roots of aralia Manchu - 5 - 6

Hawthorn blood-red - 20 - 23

The fruits of a mountain ash ordinary - 20 - 23

The fruits of black chokeberry - 18 - 20

Hips may - Rest

2. For the treatment of psoriasis containing medicinal plants, characterized in that it contains an aqueous extract of the fungus, 40% alcohol extract of the herb, as well as salicylic acid and base, including medical petroleum jelly and lanolin anhydrous in the following ratio, wt%:

An aqueous extract of the fungus - 5 - 6

40% Alcohol extract of celandine - 3 - 5

Salicylic acid - 2 - 3

Vaseline medical - 42 - 45

Anhydrous lanolin - 42 - 45

3. Means under item 2, characterized in that it is intended for local use and in which the position of the application on the affected regions funds from medicinal plants, characterized in that the inside apply the tool, including the infusion of medicinal plants by p. 1 twice a day 100 ml in the morning and at noon, in the evening, an additional 1 ml of tincture of a peony in 50 ml of water, and the lesions twice a day, put ointment on p. 2.

 

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