Biologically active additive

 

(57) Abstract:

The invention relates to food processing and pharmaceutical industries. Biologically active additive based on fat in the form of a mixture of a fatty basis and biomass of non-pathogenic microorganisms is a uniformly distributed throughout the volume of a fatty basis crushed to particle sizes of not more than 250 μm biomass of non-pathogenic microorganisms with the number of viable cells 101- 1011SOME, and as non-pathogenic microorganisms it contains microorganisms of the genus Lactobacillus and/or Bifidobacterium, and/or Streptococcus, and/or Propionibacterium, and/or Escherichia, and/or Saccharomyces, and/or yeast and/or yeast baking, and/or autolysate of microorganisms. Moreover, the SUPPLEMENTS may contain hydrogenated fat and/or vegetable oil and/or butter, and/or Combivir, and/or lanolin, and/or spermaceti, and/or wax and/or vaseline, and/or paraffin, and/or ceresin, and/or liquid paraffin, and/or artificial vaseline, and/or hydrogenated fats, and/or interesterified fats, and/or confectionery fat, and/or palmitin, and/or palm olein, and/or palm stearin and/or cocoa butter and/or vegetable oil, such as sunflower oil and/or peach oil, and/ilor, and/or amendment and biologically active substances of liquid and/or dry, such as lysozyme and/or interferon, and/or vitamins and/or interleukin and/or tumor necrosis factor -, and/or immunoglobulins. SUPPLEMENTS may contain as immunoglobulins mixture of IgA, IgG and IgM. Supplements may contain biologically active substances in the dry crushed to particle sizes of not more than 250 μm, can be used in the pharmaceutical, oil and dairy products, and provides high biological activity and stability during storage, and also extends the range of the BAD fat basis. 11 C.p. f-crystals.

The invention relates to the food industry and can be used in the production of biologically active additives (BAA) for food.

Known therapeutic drug in hard and soft forms, including the Foundation, microbial mass of live bacteria eubiotics and biologically active ingredients immunomodulating, regenerating and protective steps /1/. As bacteria eubiotics use dry microbial mass.

The disadvantages of the known therapeutic and preventive medication is incomplete use of microbial biomass in resemo the finished product.

The closest analogue of the claimed invention is bacteriostasis food product containing bacterial biomass from non-pathogenic bacteria involved in the digestion of food ingredient conservation of non-pathogenic bacteria and biologically active substances /2/.

The disadvantages of the known bacteriostasis food product is incomplete, the use of microbial biomass as a result of formation of lumps and agglomerates, stratification of the mixture and a poor distribution of microbial biomass by volume of the finished product.

The technical result of the claimed invention to provide BAA with high biological activity and stability during storage due to the most complete uniform distribution of the components throughout the volume, which increases the digestibility of dietary SUPPLEMENTS, as well as expanding the range of BAD fat basis.

This is due to the fact that the SUPPLEMENTS in the form of a mixture of a fatty basis and biomass of non-pathogenic microorganisms is a uniformly distributed throughout the volume of a fatty basis crushed to particle sizes of not more than 250 μm biomass of non-pathogenic microorganisms with the number zhiznesposobnosti of the genus Lactobacillus and/or Bifidobacterium, and/or Streptococcus, and/or Propionibacterium, and/or Escherichia, and/or Saccharomyces, and/or yeast and/or yeast baking, and/or autolysate of microorganisms.

When this BAA as a fatty basis can contain hydrogenated fat and/or vegetable oil and/or butter, and/or Combivir, and/or lanolin, and/or spermaceti, and/or wax and/or vaseline, and/or paraffin, and/or ceresin, and/or liquid paraffin, and/or artificial vaseline, and/or hydrogenated fats, and/or pereaminirovanie fats, and/or confectionery fat, and/or palmitin, and/or palm olein, and/or palm stearin and/or cocoa butter and/or vegetable oil, such as sunflower oil and/or peach oil and/or Flaxseed oil, and/or hemp oil.

The BAD may further comprise an emulsifier and/or stabilizer and/or amendment and biologically active substances in liquid and/or dry form, such as lysozyme and/or interferon, and/or vitamins and/or interleukin and/or tumor necrosis factor -, and/or immunoglobulins.

SUPPLEMENTS may contain as immunoglobulins mixture of IgA, IgG and IgM.

SUPPLEMENTS may contain biologically active substances in a dry form, and crushed to particle sizes of not more than 250 the e perfumery-cosmetic products contains non-pathogenic microorganisms with the number of viable cells in the production of 103- 108SOME. If the production of dairy products BAD contains non-pathogenic microorganisms with the number of viable cells in the production of 105- 1011SOME. BAD in the manufacture of pharmaceutical products contains non-pathogenic microorganisms with the number of viable cells in the production of 101- 109SOME. BAD in the production of oil and fat products contain non-pathogenic microorganisms with the number of viable cells in the production of 105- 1011SOME. BAD in the manufacture of sauces and/or condiments for the salad contains non-pathogenic microorganisms with the number of viable cells in the production of 105- 1010SOME.

The basis of the invention is the use in the manufacture of SUPPLEMENTS biomass of non-pathogenic microorganisms crushed to particle sizes of not more than 250 μm at maximum conservation of the number of viable microorganisms. The use of shredded biomass prevents the formation of lumps and agglomerates, the stratification of the mixture, provides uniform distribution of biomass throughout the volume of the finished product, which generally creates the condition for the best use of biomass non-pathogenic, microo the ode Lactobacillus and Bifidobacterium genus, crushed to particle sizes of not more than 250 μm, lysozyme and interferon in dry form with particle sizes last no more than 250 μm, while the mixture is a uniformly distributed throughout the volume of a fatty basis of the crushed particles. Ready BAD mixed with prescription components necessary for the preparation of lipstick, and subjected to further technological processing. The obtained lipstick contains non-pathogenic microorganisms with the number of viable cells 105SOME. Lipstick has a high biological activity and stability during storage in the uniform distribution of the components throughout the volume. Lipstick effective when eating and heylity.

Example 2. The BAD is obtained by mixing fat confectionery firm based on plasticized hydrogenated fat and dry biomass of microorganisms of the genus Bifidobacterium with a particle size of not more than 250 μm, while the mixing is carried out until obtaining a uniform distribution throughout the volume of a fatty basis of crushed particles of biomass. Received BAD mixed with the wax and emulsifier and is subjected to further technological processing of obtaining suppositories. The floor of the Suppositories have high biological activity and stability during storage in the uniform distribution of the components throughout the volume. Suppositories effective when vulvovaginitis pathology of the gastrointestinal tract.

Example 3. The BAD is obtained by mixing the butter with the dry biomass of microorganisms of the genus Lactobacillus and dry lysozyme. Before mixing with fat basis biomass of non-pathogenic microorganisms and lysozyme pre-crushed to particle sizes of not more than 250 μm and mix. With a mixture of butter with a mixture of chopped biomass and powdered lysozyme is carried out until obtaining a uniform distribution throughout the volume of a fatty basis of the crushed particles. Received the SUPPLEMENTS used in the production of butter. Received butter contains non-pathogenic microorganisms with the number of viable cells 1011SOME. Butter has a high biological activity and stability during storage in the uniform distribution of the components throughout the volume. Butter is effective in tonsillitis, pathology of the gastrointestinal tract. The use of butter in the manufacture of dietary SUPPLEMENTS does not decrease the organoleptic properties of the finished product.

Biologically active additive based on fat will find wide application salad, as well as in perfumery and cosmetics industry in the manufacture of lipstick, various creams, gels, jelly, toothpaste, etc.

Sources of information

1. Patent 2146526 EN, C1, 05.05.1999.

2. Patent 2118100 EN, C1, 30.09.1997.

1. Biologically active additive based on fat, containing a mixture of fatty basis and biomass of non-pathogenic microorganisms, characterized in that the mixture is a uniformly distributed throughout the volume of a fatty basis crushed to particle sizes of not more than 250 μm biomass of non-pathogenic microorganisms with the number of viable cells in a mixture of 101- 1011SOME, and as non-pathogenic microorganisms it contains microorganisms of the genus Lactobacillus and/or Bifidobacterium, and/or Streptococcus, and/or Propionibacterium, and/or Escherichia, and/or Saccharomyces, and/or yeast and/or yeast baking, and/or autolysate of microorganisms.

2. Biologically active additive to food based on fat under item 1, characterized in that as a fatty basis it contains hydrogenated fat and/or vegetable oil and/or butter, and/or Combivir, and/or lanolin, and/or spermaceti, and/or wax and/or vaseline, and/or paraffin, and/or ceresin, and/or liquid paraffin, and/or iskeleton, and/or palm olein, and/or palm stearin and/or cocoa and/or vegetable oil, such as sunflower oil and/or peach oil and/or Flaxseed oil, and/or hemp oil.

3. Biologically active additive to food based on fat according to any one of paragraphs.1 and 2, characterized in that it additionally contains an emulsifier and/or stabilizer and/or amendment.

4. Biologically active additive to food based on fat according to any one of paragraphs. 1 to 3, characterized in that it further comprises a biologically active substance in liquid and/or in dry form, such as lysozyme and/or interferon, and/or vitamins and/or interleukin and/or tumor necrosis factor -, and/or immunoglobulins.

5. Biologically active additive to food based on fat under item 4, characterized in that the antibodies it contains a mixture of IgA, IgG and IgM.

6. Biologically active additive to food based on fat under item 4 or 5, characterized in that the biologically active substances it contains in a ground state with a particle size of not more than 250 μm.

7. Biologically active additive to food based on fat according to any one of paragraphs. 1 - 6, characterized in that in the manufacture of parfumernaya 103- 108SOME.

8. Biologically active additive to food based on fat according to any one of paragraphs.1 - 6, characterized in that in the production of dairy products it contains non-pathogenic microorganisms with the number of viable cells in the production of 105- 1011SOME.

9. Biologically active additive to food based on fat according to any one of paragraphs. 1 - 6, characterized in that in the manufacture of pharmaceutical products it contains non-pathogenic microorganisms with the number of viable cells in the production of 101- 109SOME.

10. Biologically active additive to food based on fat under item 9, characterized in that the pharmaceutical products represent the ointments, pastes, liniments, suppositories, jellies, gels.

11. Biologically active additive to food based on fat according to any one of paragraphs. 1 - 6, characterized in that the production of oil and fat products it contains non-pathogenic microorganisms with the number of viable cells in the production of 105- 1011SOME.

12. Biologically active additive to food based on fat according to any one of paragraphs. 1 - 6, characterized in that in the manufacture of sauces and/or condiments for the salad it contains nematogen

 

Same patents:

The invention relates to iododerma biologically active compositions containing iodine and halides of nitrogenous bases of the formula I, where the values of the radicals a, b, C, R, X and m are specified in the claims
The invention relates to medicine, in particular to composite medicines used for the treatment of skin diseases

The invention relates to medicine, namely dentistry, concerns the means for the treatment of diseases of the oral cavity

The invention relates to pharmaceutical industry, production of medicines intended to treat herpes infections of the skin and mucous membranes

The invention relates to medicine, in particular to pharmacology relates to a gel-like aqueous composition for intrarectal injection in the treatment of hemorrhoids and/or in the treatment of anorectal diseases

The invention relates to an anti-inflammatory drug for external use, comprising as active ingredient nimesulide

The invention relates to medicine and pharmaceutical industry, in particular to the creation and production of anti-inflammatory and antimicrobial agents for local use

Bactericidal togel // 2157206
The invention relates to medicine, namely to bactericidal hotovely
The invention relates to medicine, in particular to pharmacology concerns the creation of tools for the treatment of skin diseases

The invention relates to medicine, in particular to pharmacology, and can be applied in proctology for the treatment of hemorrhoids and fissures of the rectum

The invention relates to medicine and pharmaceutical industry and for the development of new drugs

The invention relates to medicine, namely to the pharmaceutical industry, and for candles, which can find use for the treatment of external and internal hemorrhoids and rectal fissures

The invention relates to an external preparation for topical application, in particular to the outer local drug use, containing as activitiesthese substance 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol or its pharmaceutically acceptable acid salt additive

Rectal tool // 2152204
The invention relates to medicine and pharmaceutical industry and for the creation of new drugs used for the treatment of acute and chronic prostatitis

The invention relates to medicine, namely the pharmaceutical industry and relates to a medicinal product for the treatment of proctologic diseases
The invention relates to medicine, technology of medicinal forms with bacterial drugs
The invention relates to the pharmacy, the pharmaceutical form of human recombinant interferon Alfa-2 - rectal and vaginal suppositories

The invention relates to medicine, namely to Virology, immunology, gynecology and pharmacology
The invention relates to medicine
Up!