Biologically active additive

 

(57) Abstract:

The invention relates to food industry, namely, diet and preventive products, as well as to cosmetic and pharmaceutical industry. Biologically active additive as macro - and micronutrients, adaptogene and/or detoxifier contains a concentrate of chlorophyll derivatives and related compounds, where chlorophyll derivatives are 33000 mg%, related compounds: carotenoids - up to 1,500 mg%, vitamin E - to 360 mg%, fatty acid up to 30%, and can optionally contain vegetable and animal raw materials. This allows you to get a Supplement that optimally balanced components and has antiseptic, adaptogenic and/or detoxifying properties. 16 C.p. f-crystals.

The invention relates to food industry, namely, diet and preventive additives, herbal, cosmetic and pharmaceutical industry.

It is known that chlorophyll and its derivatives possess high biological activity, which manifests itself in the form of anti-inflammatory, antimicrobial, and regenerative deodorizing properties (Chemomorsky S. A., Segelman of Auroville use in food and pharmaceutical industries as a natural dye, deodorizing agent and additive in chewing gum, confectionery and cosmetics (S. Shwartz et. al. - Chlorophylls in foods, "Crit. Rev. Food Sci. Nutr", 1990, 29 (1), p. 1-17).

However, in all these cases, using purified from accompanying substances chlorophyll, which, after treatment, partially loses its biological activity. There are many examples when trying to isolate the active ingredient from plants, observed a decrease in biological activity in a few dozen times, such as Valerian root. And clearing derivatives of chlorophyll - a very time consuming process that requires a large consumption of solvents and high energy consumption, which increases the cost of the product itself.

You know the tool Petalon" and "Petalon-M" for the prevention of malignant neoplasms on the basis of chlorophyll derivatives (U.S. Pat. N 2031654, A 61 K 35/80, 31/40, BI N 9 from 27.03.95). Chlorophyll derivatives obtained in the form of a copper derivative of chlorophyll lipid complex of kelp. This tool comes in the form of medical-preventive additive containing alcohol under the trade name "Petalon". The tool has a strong onkoprofilakticheskim and immunostimulating action.

The closest T3.97).

However, this Supplement does not have a sufficiently strong curative effect, because poorly balanced on vital components.

The technical result of the claimed invention to provide a BUD from a plant raw material, which is optimally balanced for vital components and can show properties as adaptogens and detoxicants, and General properties due to interchangeable actions, and also has antiseptic properties that can significantly extend the scope of its application and use for the prevention and treatment of human disorders caused by active oxygen, where as the active agent concentrate is used, chlorophyll derivatives, isolated from various plant materials, this allows the use of SUPPLEMENTS to prevent premature aging and damage to the body caused by accumulation of free radicals, in such diseases as asthma, sepsis, diseases, sclerosis of cerebral arteries, cataracts, skin diseases, coronary heart disease, diabetes, rheumatism, chronic pulmonary emphysema, and various autoimmune diseases.

It is up to the and chlorophyll derivatives (HRP), containing up to 33% various derivatives of chlorophyll, namely pheophytin and/or pheophorbide, and/or chlorine, and/or their salts and related compounds - carotenoids - up to 1,500 mg%, vitamin - E vitamin - up to 360 mg%, fatty acid up to 30%. Moreover, as a concentrate of chlorophyll can be used water-soluble, fat-soluble HRP concentrate and/or their mixture. As derived chlorophyll contains metal derivatives of chlorophyll, namely zinc and/or copper and/or cobalt and/or iron and/or silver and/or palladium salts. In addition, SUPPLEMENTS may additionally contain vitamins and/or sugars and/or polysaccharides and/or alginic acid and their salts, and/or flavonoids, and/or glucosides, and/or amino acids, and/or sterols, as their sources using vegetable raw materials and/or animal, such as medicinal plants, and/or grain and/or vegetable raw materials or extracts from them, and/or deer, and/or deer, and/or deer, and/or extracts of organs of animals and/or fish and/or aquatic organisms. This BAA may be used in the manufacture of confectionery - up to 4 wt.%, in the manufacture of bakery and pasta - 1 wt.%, in the production of fat and oil products - up to 5 wt.%, when production is selected drinks up to 5 wt.%, in the production of perfumes and cosmetics - up to 5 wt.%. If the production of tablets, capsules, wafers, pastes, ointments and suppositories BAD additionally contains a binder and/or processing AIDS. And the BAD can be used in the manufacture of suture and dressing material, since it has antiseptic and wound-healing effect.

New and unknown properties of the concentrate HRP detected during testing at the Institute of Oncology. Professor N. N. Petrova Ministry of health of the Russian Federation.

As a result of the tests it was found that BAA is not toxic: LD50 in mice was 285 mg/kg when administered intravenously, 400 mg/kg - intraperitoneal and 10 g/kg per os. HRP introduced intraperitoneally, prevent caused by chemical and X-ray radiation in animals. This action SUPPLEMENTS can be explained by the content of its complex HRP, especially pheophorbide, which is a trap and tusitala singlestage oxygen for X-rays and chemical agents, as well as the combined action of the whole complex of biologically active substances of dietary SUPPLEMENTS, including related substances. This is due to the synergistic action of HRP and/or derivatives of porphyrins in owls is hypoxia plant materials. Detoxicant properties BAA appear in protecting the body from radiation and other damaging environmental influences.

In addition, it was found that the BAD is well absorbed by the cell due to the complex of active substances, such as chlorophyll derivatives, as are conductors through a biomembrane cells.

Minerals are better absorbed by the body when using BAD per os, especially in pathological processes in the body related to premature aging or the accumulation of active oxygen, leading to a number of chronic diseases.

We have also studied the adaptogenic effect of concentrate PH in rats exposed to toxic and carcinogenic agent N-methyl-N-nitrosoanatabine (CMA).

The SUPPLEMENTS increased the survival of animals subjected to the CMA. Mechanisms adaptogenic actions of the BAD can be explained, apparently, as due to the activation of immunity under the influence of this concentrate, and detoxicating and its antiseptic action.

As shown by our study, depending on the dosage and route of administration of HRP concentrate, it can be vzaimozatmeniya action Aditi achieved through detoxicant-antiseptic properties of the concentrate, and due to the adaptogenic. The discovery of new properties of the concentrate PH can significantly extend the scope of its application. It can be used in diet and preventive nutrition disorders caused by active oxygen to facilitate oxidative load in people suffering from various pulmonary, cardiovascular and autoimmune diseases, as well as under adverse environmental factors.

BAD optimally balanced on vital elements and depending on the disease can be made by adjusting for these items the BAD can be made in the form of solutions, tablets, capsules, plates, ointments and pastes.

Example 1.

As a dietary Supplement, used the HRP concentrate, derived from lipid complex needles of pine and spruce with fish oil. Concentrate HRP fought off an unpleasant odor and taste of fish oil. Capsules bright green color was used as an adaptogenic means to increase the overall resistance of the organism. However, after two weeks of constant use has been observed detoxicant effect, which increased towards the end of the month.

Example 2.

As a dietary Supplement, used the end of the research Institute of non-alcoholic beverage in an amount of 0.1%. The resulting drink had a nice green color and smell of freshly cut grass and has found its use as a preventive, adaptogenic remedy for colds, acute respiratory infections and flu.

Example 3.

Concentrate HRP was mixed with vegetable raw materials (wheat bran, oat) in the amount of 0.5% and used to improve the activity of the gastrointestinal tract and absorption of macro - and microelements in the gut, to normalize bowel flora. Especially good results were obtained in people suffering from constipation and iron deficiency anemia when iron absorption in the intestine is broken. Here the BAD shows as detoxicant properties and adaptogenic, improves the absorption of minerals.

Example 4.

The HRP concentrate, derived from lipid complex of kelp, containing copper derivative of chlorophyll, mixed with DNA Asai obtained from salmon, and used this BAD as a means of improving performance and endurance under extreme conditions. This Supplement was given to athletes and individuals whose work involves heavy physical loads. Therefore it is established improved physical health, improved vision is the additives.

Example 5.

SUPPLEMENTS containing HRP concentrate, derived from algae laminaria in the form of syrup, was given to the experimental animals at a dose of 80 mg/kg orally before the experiment and after 1, 2, 3 days after infection. Animals were infected with influenza A, in three days the animals in the lungs developed typical flu-like hemorrhagic, bronchopneumonia. The use of dietary SUPPLEMENTS led to a decrease in the intensity of lesions of the bronchial epithelium. The foci of influenza defeat was clearly limited from healthy tissue compared to control (untreated animals). Inflammatory infiltration in the bronchi limited during the first three days of the infection in the lower parts of the lungs and inhibited the replication of the virus due to the antiseptic and detoxicants of action.

1. Dietary Supplement that contains micro - and macronutrients, adaptogen and/or detoxifier, characterized in that as the micro - and macroelements, adaptogene and/or detoxifier contains a concentrate of chlorophyll derivatives and related compounds, where chlorophyll derivatives up to 33000 mg%, related compounds: carotenoids - up to 1,500 mg%, vitamin E - to 360 mg%, fatty acid up to 30%.

3. BAD under item 1 or 2, characterized in that as a derivative of chlorophyll contains pheophytin, and/or pheophorbide, and/or chlorine, and/or their salts.

4. BAD under item 1 or 3, characterized in that as a derivative of chlorophyll contains metal derivatives of chlorophyll, such as zinc and/or copper and/or cobalt and/or iron and/or silver and/or palladium salts.

5. BAD on p. 4, characterized in that it further comprises vitamins, and/or sugars and/or polysaccharides and/or alginic acid, and their salts, and/or glucosides, and/or flavonoids, and/or amino acids, and/or sterols.

6. BAD on p. 5, characterized in that as sources of vitamins, and/or sugars and/or polysaccharides and/or alginic acids and their salts, and/or glucosides, and/or flavonoids, and/or amino acids, and/or sterols contains animal and/or vegetable raw materials.

7. BAD on p. 6, characterized in that the quality of plant raw material contains medicinal plants, and/or grain and/or vegetable raw materials or their extracts.

8. BAD on p. 6, characterized in that as an animal feedstock contains the antlers, and/or deer, and/or deer, and/I fact, what in the manufacture of bakery and pasta products, the amount of concentrate makes up to 1 wt.%.

10. BAD according to any one of paragraphs.1 to 8, characterized in that the production of oil and fat products, the amount of concentrate makes up to 5 wt.%.

11. BAD according to any one of paragraphs.1 to 8, characterized in that the production of meat and dairy products, the amount of concentrate makes up to 3 wt.%.

12. BAD according to any one of paragraphs.1 to 8, characterized in that in the manufacture of soft drinks, the amount of concentrate makes up to 5 wt.%.

13. BAD according to any one of paragraphs.1 to 8, characterized in that the production of fish products, the amount of concentrate makes up to 10 wt.%.

14. BAD according to any one of paragraphs.1 to 8, characterized in that in the manufacture of confectionery, the amount of concentrate makes up to 4 wt.%.

15. BAD according to any one of paragraphs.1 to 8, characterized in that in the production of perfumery and cosmetic products, the amount of concentrate makes up to 5 wt.%.

16. BAD according to any one of paragraphs.1 to 8, characterized in that it contains a binder and/or components for tableting and encapsulation, creation records, pastes, ointments, bandages and dressings.

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