Drug

 

(57) Abstract:

The invention relates to medicine and relates to a medicinal product containing the packet of the granules for the preparation of effervescent drink acetylsalicylic acid and ascorbic acid. The invention lies in the fact that it contains acetylsalicylic acid and ascorbic acid, and optionally contains proteins, carbohydrates, fats, dairy, retinol, thiamin, Riboflavin, ergocalciferol, calcium, phosphorus, magnesium, zinc, iodine when specified in the text describing the ratio of the components. The invention provides improved portability of medicines by patients. 2 C.p. f-crystals, 1 tab., 3 Il.

The invention relates to medicine and pharmacology, non-narcotic analgesics and can be used as a drug in the class of aspirin for the treatment of patients.

Known drug containing packet of granules for the preparation of effervescent drink acetylsalicylic acid and ascorbic acid (vitamin C) [1].

The disadvantage of this drug is poor tolerability of patients, especially patients suffering from disease is their application in medical practice with this medication.

The purpose of the invention is the improvement of portability of medicines by patients.

The goal in medicinal product containing the packet of the granules for the preparation of effervescent drink aspirin and ascorbic acid, is achieved by the fact that the drug also contains proteins, carbohydrates, fats, dairy, retinol, thiamin, Riboflavin, ergocalciferol, calcium, phosphorus, magic, zinc, iodine in the following ratio of components:

Acetylsalicylic acid, g - 0,1 - 0,5

Protein g - 1,355 - 6,775

Carbohydrates, g - 1,79 - 8,95

Fats dairy, g - 1,425 - 5,7

Retinol, mg - 36 - 180

Thiamine, g - 0,015 - 0,075

Riboflavin, g - 0,055 - 0,275

Ascorbic acid, d - 0,07 - 0,35

Ergocalciferol, mg - of 0.625 to 2.5

Calcium, g - 0,055 - 0,275

Phosphorus, g - 0,031 - 0,155

Magnesium, Mr. 0,00375 - 0,01875

Zinc, Mr. 0,0175 - 0,7

Iodine, mg - 2,7 - 13,5

While this drug may be placed in sweetamanda the container capsule.

Also, the drug can be made in the formula dispersible (effervescent) tablets.

Realization of this goal is illustrated in the drawing, where

in Fig. 1 - bag dispersible drug in the of dispersible (fizzy) drink;

in Fig. 3 is a medicinal product in the form of dispersible (effervescent) tablets.

Drug 1 in the bag 2 and the container capsule 3 (Fig. 1, 2) contains a granulate 4 for the preparation of effervescent (dispersible) drink of aspirin and ascorbic acid and add to it the white powder 5, consisting of protein, carbohydrates, fats, dairy, complex vitamins: A, B1B2, D and trace elements: Ca, Mg, P, Zn, Y, in the following ratio of components (ingredients): in medicine (g) and retinova equivalent (mg), respectively:

Acetylsalicylic acid, g - 0,1 - 0,5

Protein g - 1,355 - 6,775

Carbohydrates, g - 1,79 - 8,95

Milk fat, g - 1,425 - 5,7

Retinol (vitamin A),mg - 36 - 180

Thiamine (vitamin B1), g - 0,015 - 0,075

Riboflavin (vitamin B2), g - 0,055 - 0,275

Ascorbic acid (vitamin C), g - 0,07 - 0,35

Ergocalciferol (vitamin P2),mg - of 0.625 to 2.5

Calcium (Ca), g - 0,055 - 0,275

Phosphorus (P), g - 0,031 - 0,155

Magnesium (Mg), g - 0,00375 - 0,01875

Zinc (Zn), g - 0,0175 - 0,7

Iodine (J), mg - 2,7 - 13,5

By dissolving the contents of bag 2 (Fig. 1) or container-capsules-3 (Fig. 2) in water (200 mg) is formed fizzy drink - a cocktail of therapeutic character, good usvoiv the way and as a painkiller, antipyretic, anti-inflammatory and Antirheumatic drugs especially patients who are prescribed to receive large doses of drugs, such as aspirin or known "Aspro C Forte". However, the side effects last on the gastrointestinal tract leads to bleeding, and a decrease in such cases, the dosage is known drugs decreases their efficiency and achieving therapeutic goals.

Introduction in the claimed medicinal product components nutritious and high in calories (energy value 127 kcal) substances with a complex of vitamins and minerals designed to satisfy the emerging needs of the frail body of nutrients: proteins, carbohydrates, dairy fats; vitamins: C, A, B1B2, D and trace elements: Ca, Mg, P, Zn, J in the composition of the medicinal product during the period of his admission to the intensification of the biological processes of carbohydrate, protein and fat metabolism in the body and increase body resistance to disease, and their combination (carbohydrates, proteins, milk fat, vitamins, trace elements) with acetylsalicylic acid dosage what is act drug more effectively and to facilitate its portability patients, contributing more soon his recovery.

The active components of the claimed medicinal product, such as

1.1 acetylsalicylic Acid (Acidum acetylsalicylium) can be represented by the formula salicylic ester of acetic acid:

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In combination with selected complex of vitamins and minerals acetylsalicylic acid in medicinal tool performs the function more effective and acceptable means for the organism in comparison with the known [1] , especially the functions of anti-inflammatory, Antirheumatic, analgesic, antipyretic actions. With its integrated complementary activity is better absorbed and tolerated by the body, reducing its known undesirable effect on the capillaries of the mucous membrane of the gastrointestinal tract, helping in conjunction with the claimed medicinal product components to reduce bleeding of the gastrointestinal tract and ulcerogenic action in its application.

1.2. Vitamins

1.2.1. Retinol (Petinolum). Vitamin A (Vitammum A):

TRANS-9,13-dimethyl-7-(1,1,5-trimethylcyclohexen-is the rotary has a direct effect on increasing the body's resistance to disease of the mucous membranes as the respiratory tract, and the digestive tract, helping to increase the body's resistance to infectious and chemical stimuli.

1.2.2. Thiamine (Thiammum). Vitamin B1(Vitaminum B1):

4-methyl-5-oxyethyl-N-(2-methyl-4-amino-5-methylpyrimidin)-tiazoly bromide hydrobromide, which may be represented by the formula:

< / BR>
In medicine vitamin B1has an impact on the improvement of carbohydrate, protein, fat metabolism in the body and has a positive effect on the perception of medicines by patients who have a predisposition to the occurrence of side effects of known drugs [1], or, for example, "aspirin".

Also known positive results in the treatment of vitamin B1patients with peptic ulcer of stomach and duodenum, in Antonii intestines, liver disease, myocardial degeneration, peripheral vascular spasm, which is important for the use of the claimed medicinal product as a preventive medication when it is receiving low doses.

1.2.3. Riboflavin (Piboflavinium). Vitamin B2(Vitaminum B2):

6,7-demethyl-9-(D-1-ribitil)-izoalloksazin, which may be represented by formulas of the CSOs and fat metabolism in the body, promotes the healing of wounds and ulcers, inflammation in the patient.

1.2.4. Ascorbic acid (Acidum ascorbinicum). Vitamin C (Vitaminum C): -Lactone 2,3-degidro-L-gulonovoy acid and may be represented by the formula:

< / BR>
Vitamin C in combination with vitamins A, B1B2D2in medicine has strongly pronounced redox properties and participating in the regulation of redox processes in the body, carbohydrate metabolism, clotting of the blood, regeneration of the tissues, formation of steroid hormones, as well as participating in the synthesis of collagen and procollagen, the normalization of the capillary permeability and acting in combination with acetylsalicylic acid, contributes to the reduction of its irritating effect on the capillaries of the mucous membrane of the gastrointestinal tract, reducing the bleeding in this tract and accelerating the healing of wounds and simultaneously performs the functions of supplementation of vitamin C in the body, while allowing to increase the effectiveness of the treatment of colds, fever, and improve responsiveness and increase the range of application of this drug in comparison with the known [1].

1.2.5. the which can be represented by the formula

< / BR>
Vitamin D regulates the metabolism of phosphorus and calcium in the body, and its small dose of medicine is designed to increase the efficiency of the treatment of the inflammation of the mucous membranes of the respiratory tract and the gastrointestinal tract in combination with vitamins C, A and group B.

1.3. Trace elements: calcium (Ca), phosphorus (P), magnesium (Mg), zinc (Zn), iodine (J) are in medicine in microdoses as necessary intensifiers biological process in the body when taking medicines and exercise their positive impact in the complex with all of the components of the drug.

Application of known dispersible form of the medicinal product to receive in the form of fizzy drink, owing to a well-known sodium bicarbonate or calcium bicarbonate to achieve a known manner a faster allocation salicylates declared drugs from the body, which is also a significant factor in reducing the irritant action of salicylates in the gastrointestinal tract.

In addition to bags with granules (Fig. 1) and containers-capsules (Fig. 2) with a pelletizer to prepare shipachev is haunted by obtaining dispersible (effervescent) tablets (Fig. 3).

Composition, doses and modes of application of the offered medicines are determined by the attending physician according to the testimony, adequate body condition of the patient, and are shown in table 1 for the preparation of "therapeutic cocktail" (bubbly) examples of compounds 1, 2, 3:

The proposed composition of the medicinal product can be recommended for use for medicinal purposes as an anti-inflammatory, antipyretic, analgiziruyuschee remedy for colds and rheumatic diseases, fever and pain for all age groups, except children under 4 years of age and pregnant women.

We recommend the following dosage drugs:

adults - 1 sachet of effervescent granules of powder or 5 effervescent tablets per reception, the highest daily dose of 6-8 tea bags or 30-40 tablets;

- children from 4 to 7 years - 1/2 sachet of granules of powder to 3 times a day; children from 8 to 11 years: 1/2 sachet up to 4 times a day; children from 11 to 15 years - 1 sachet of granules of powder to 4 times per day.

The usual course of treatment is 3-5 days. When treating rheumatoid arthritis, the daily dose may be increased depending on the body condition of the patient, his physician, and treatment deferred funds (composition No. 1 table. 1) a day for 10-15 days at the doctor.

Thus, the claimed medicinal product, in contrast to the known [1] , has a new quantitative and qualitative components, has a high energy and nutritional value, reduces unwanted actions on the gastrointestinal tract, promotes better absorption and improves its portability.

This medicine is applicable in medical practice for the treatment and prophylaxis of patients with more favorable and effective non-narcotic analgesics.

Sources of information

1. "AsproC Forte". Register of medicines of Russia, radar - Doctor. - M.: Remus, 1997/1998, S. 157.

1. Drug containing packet of granules for the preparation of effervescent drink acetylsalicylic acid and ascorbic acid, characterized in that it additionally contains proteins, carbohydrates, fats, dairy, retinol, thiamin, Riboflavin, ergocalciferol, calcium, phosphorus, magnesium, zinc, iodine in the following ratio of components retinova equivalent:

Acetylsalicylic acid, g - 0,1 - 0,5

Protein g - 1,355 - 6,775

Carbohydrates, g - 1,79 - 8,95

Korbanova acid, g - 0,07 - 0,35

Ergocalciferol, mg - of 0.625 to 2.5

Calcium (Ca), mg - 0,055 - 0,275

Phosphorus (P) mg - 0,031 - 0,155

Magnesium (Mg), mg - 0,00375 - 0,01875

Zinc (Zn), mg - 0,0175 - 0,7

Iodine (J), mg - 2,7 - 13,5

2. Drug under item 1, characterized in that it is placed in sweetamanda the container capsule.

3. Drug under item 1, characterized in that it is made in the form of dispersible (effervescent) tablets.

 

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