Immunostimulant

 

(57) Abstract:

The invention relates to medicine, to the creation of medicines from plant material. The composition includes a 1.5% solution of thick licorice root extract in distilled water, enriched ex tempore gaseous nitrogen in a volumetric ratio of 1: 10 to 1:15. The tool speeds up the recovery levels of lymphocytes and neutrophils in the blood and the activity of the phagocytic response of neutrophils. 3 table.

The invention relates to medicine, namely to clinical pharmacology.

The known composition of the cocktail, including glitsiram at a dose of 1-10 mg/kg weight of distilled water as a dispersion medium carbon dioxide gas in a volumetric ratio of 1:10-1:15 (Priority help from 29.11.94 N 94042565).

The composition has an immunostimulating effect, which is to accelerate the recovery of the levels of lymphocytes and neutrophils in the blood, and the activity of the phagocytic response of neutrophils.

The lack of structure is the lack of recovery of the oppressed in the exposure of the receptor function of T-lymphocytes (levels E-, ETrand Eact-rosethorne.

We offer boat (HPP) of 1.5%, distilled water as the dispersion medium is nitrogen in a volumetric ratio of 1:10-1:15.

The manufacture of the composition is produced as follows. First prepare a 1.5% solution of thick licorice root extract in distilled water, after which ex tempore produce enrichment solution with gaseous nitrogen in a volumetric ratio of 1: 10-1: 15. The composition is administered to experimental animals such as rats, in a dose of 5 mg/kg body weight daily for 10 days with subsequent determination of immunological parameters.

The experiment was conducted on 84 rats male Wistar rats weighing 120-150 g Animals were divided into 6 groups (14 rats per group). Intact rats group 1 served as a common control for all other groups. Rats of group 2 received a single external irradiation dose of 3 3V. Animals of group 3 were Polish within 10 days of daily carbon cocktail with 1.5% solution of thick licorice extract (5 mg/kg). Animals 4 groups were initially irradiated at a dose of 3 3V, then within 10 days Polis carbon cocktail.

Groups 6 and 5 corresponded to groups 4 and 3 according to the methods of influence by the difference in gas composition cocktail (instead of carbon dioxide applied nitrogen).

TrROCK) and active (EandROCK) and antibody productive (AOK) cells in the spleen.

Found that on the 23rd day after irradiation (directly after completing the course, admission procedure cocktail) the purpose of these procedures significantly (P<0,001) increased decreased radiation exposure to the General reception of the T-limfotsitov, and the maximum such increase was noted in the group of animals treated with nitrogen cocktail. The most distinct tendency to normalization of the levels of active and theophylline-resistant outlets was also observed in this group.

After 113 days after irradiation this pattern is particularly pronounced.

So, if all irradiated groups was steady decline in all three indicators, the appointment of nitrogen cocktail warned this decline.

Sledovatel it by way of the prototype and can be recommended in similar cases in the radiology clinic.

Immunostimulant, including dense extract of licorice root and a dispersion medium, wherein the dispersion medium is distilled water and nitrogen in a volume ratio of 1:10 to 1:15.

 

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