Ointment "zwar" for the treatment of purulent and infected wounds of different etiology

 

(57) Abstract:

The invention relates to medicine applies the ointment "Zwar" for the treatment of purulent and infected wounds of various etiologies. The invention lies in the fact that the ointment contains the oleoresin of pine and/or spruce gum, beeswax, butter, vegetable oil, fats interior, propolis and onion turnip in certain quantities. The invention provides improved therapeutic efficacy ointment by increasing the spectrum of therapeutic action and reduce the duration of treatment,

The invention relates to medicine, in particular to therapeutic ointments anti-inflammatory action with biostimulating properties for the treatment of purulent-inflammatory processes of the skin and mucous membranes, cuts, otitis, tonsillitis, mastitis, cervical erosion, burns, felon, psoriasis, herpes, dermatitis, allergic rashes, etc.

Known ointment "Benin" for the treatment of purulent and infected wounds variety of etiologii consisting of pine oil, propolis, pine resin, spermaceti and fat penguin with a mass ratio of components 3 - 7 : 0,5 - 1,5 : 0,5 - 1,5 : 1,5 - 2,5 : 7 - 15 respectively (see RF Patent N 2058776, class A 61 K 9/06, 1995).

However, this ismism of the present invention to the technical essence is anti-inflammatory ointment "Picton", containing in wt.%: 19,0 - 21,0 pine resin; a 16.8-17.5 beeswax; 10,5-12,0 chalk; fatty base - oil industrial - other (see RF Patent N 2097056, class A 61 K 35/78, A 61 K 9/06, 1995).

The disadvantage of this known ointment is that as a fatty basis it contains oil industrial, which limits the area of application of this ointment only veterinary.

In addition, the ointment has limited therapeutic efficacy.

The aim of the invention is to increase therapeutic efficacy of the ointment by increasing the spectrum of therapeutic action and reduce treatment time.

An additional goal is to expand the range of therapeutic ointments while ensuring the availability and Nezavisimosti resource base.

This objective is achieved in that the known ointment for the treatment of purulent and infected wounds variety of etiologii containing pine resin, beeswax, fatty base and additive, as pine resin contains a resin of pine and/or spruce gum, as a fatty basis - butter, vegetable oil, pork fat interior and/or fat beef interior and/or fat goose interior and/or fat sheep interior material The gum resin and/or resin of spruce - 7,0 - 8,0

Beeswax - 6,7 - 7,3

Butter - 6,5 - 7,5

Vegetable oil - 6,5 - 7,5

Fat pork interior and/or fat beef interior, and/or fat goose interior, and/or fat sheep interior - 19,0 - 22,0

Propolis - 0,5 - 1,0

Onion turnip - Rest

From the patent and scientific literature is unknown to us healing ointment containing a combination of the above ingredients in the proposed quantitative ratio that allows to make a conclusion about the novelty of the claimed technical solution.

The achievement of this goal due to the fact that the proposed ointment has multifaceted effects: antimicrobial, analgesic, osmotic, thanks biologically active substances extracted from propolis, beeswax, pine resin, onion turnips and fatty basis of complex composition.

Ointment such structure allows to effectively work on purulent and infected wounds variety of etiologii, until full recovery in a short time.

For the preparation of the proposed ointment "Zwar" were used the following materials:

the oleoresin of pine and/or spruce gum on the EAST 13-128-82;

- beeswax GOST 21179-75;

- butter on the Jana cleared;

fat goose interior cleaned;

- fat sheep's interior cleaned;

- onion turnip in crushed form.

The proposed ointment was prepared as follows.

In the capacity of add 7.5 g of fat pork interior, 6.5 g fat beef interior, 5 g fat goose interior, 7.5 g of vegetable oil refined, 6.5 g of butter melted, 7 g of beeswax and the resulting mixture is melted. Then in the melt, add 7 g of oleoresin of pine and mix thoroughly. Then, the resulting mixture was added 0.5 g of propolis and 52,5 g onion-chopped turnips. The mixture is again heated on low heat with stirring and filtered. The result of the claimed ointment "Zwar".

Ointment with the other contents of the ingredients are prepared in a similar manner.

The ointment is stored in a glass container in a dark, cool place for up to 5 years without loss of original activity.

Ointment "Zwar" when room temperature is a homogeneous solid consistency, yellow in color with a pleasant smell of pine resin. Upon contact with the body or heated above 25-30oC ointment becomes fluid and plastic. In water and alcohol insoluble. The ointment is non-toxic.

Example 1. Patient A. Loginov 8 months. Penetrating wound of cheek, obtained from the puncture with a fork on the inside of the mouth. The patient was underwent surgical treatment, prescribed antibiotics, superimposed bandage with ointment Vishnevskogo, but it did not give a positive effect, the wound suppurated, kept persistent swelling of the cheeks. The child was debilitated by pain from wounds and lack of sleep. Only two weeks later he was wrapped up in bandages with ointment "Zwar", at this time, the antibiotics were not used. The first dressings after removal were richly impregnated purulent content. At the end of the second day the wound was cleansed from pus, swelling disappeared. On the fourth day the wound is completely closed. Allergies were not observed.

Example 2. Patient to receive his report I. 36 years. Treated for psoriasis within one year different medications, including ointments: Ichthyol, sulfur-tar, salicylic, ftorokorta, but a strong positive effect was not observed. Beginning primenjaja acquired a pinkish color, disappeared itching. Allergies were not observed.

Example 3. Sick of Dry Century. 23 years. Felon nail of the index finger of the right hand: there was a sharp pain in the area of the nail, aggravated by pressure on him, reddening of skin of finger swelling. Without surgical treatment was applied bandage with ointment "Zwar", the next day the pain disappeared, occurred after the pus on a blindfold. Dressings were changed 2 times per day. After 2 days, the healing was complete. Allergies were not observed.

Example 4. Patient Tretyakov L. 25 years. Purulent lactation mastitis. It was made drainage of the breast from two sides, prescribed antibiotics. The dressing is applied with ointment Vishnevskogo for 2 days did not give a positive result. Then was applied bandage with ointment "Zwar", 8 hours occurred after pus, swelling Breasts, decreased temperature. After 3 days were painful symptoms, on the fifth day is completely closed wounds from drainage, the healing was complete. Allergic reactions were not observed.

Treatment ointment "Zwar" in almost all cases passed with a positive result was observed acceleration of wound healing without complications and pobochnymi the effect of the ointment on the regenerative processes of the connective tissue and epithelium, which indicates the biostimulating effect of ointments and confirmed by the shortening of the healing of wounds.

Thus, the proposed ointment accelerates the rejection of necrotic tissue RAS, shorten the time of healing and stimulates the development of young granulation tissue with acceleration of its maturity, enhances proliferation of epithelium.

Ointment for the treatment of purulent and infected wounds of various etiologies, containing the active substance, pine resin, beeswax, fatty base, characterized in that the active substance ointment contains propolis and onion turnip, as pine resin contains a resin of pine and/or spruce gum, as a fatty basis - butter, vegetable oil, pork fat interior and/or fat beef interior, and/or fat goose interior, and/or fat sheep's interior in the following ratio of ingredients, wt.%:

The oleoresin of pine and/or spruce gum - 7,0 - 8,0

Beeswax - 6,7 - 7,3

Butter - 6,5 - 7,5

Vegetable oil - 6,5 - 7,5

Fat pork interior, and/or fat beef interior, and/or fat goose interior, and/or fat sheep interior - 19,0 - 22,0

Propolis - 0,5 - 1,0

Onion turnip - Rest

 

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