Aerosol disinfectant "vilag-2"
(57) Abstract:Means for disinfection of air, surfaces, furniture, equipment and premises medical and health care institutions contains as an organic polymer binder is a copolymer of vinylpyrrolidone with vinyl acetate content of the first component 30 wt.% (resin SWAP-3), bactericidal additive 2-methyl-5-di(trifluoromethyl) oxymethylene (vilain), propellant, for example (Halocarbon 12) or a mixture of 12 and halon halon 11 in the ratio of 1 : 1 or liquefied hydrocarbon gas is purified. The tool has a high disinfectant properties (% disinfection - 100), does not reduce the activity for a long time. 1 C.p. f-crystals, 5 PL. The invention relates to sanitation and relates to aerosol disinfectants may be used for disinfection of air, surfaces, furniture, equipment and premises medical and health care institutions.Known aerosol disinfectants: an aqueous solution of hydrogen peroxide and formaldehyde ("Disinfection aerosols" p. P. Lerski, C. M. Tsetlin.- M.: Medicine, 1981, S. 130-135). However, they have drawbacks. The peroxide bleached obratimaya activity against spore-forming and acid-resistant forms of microorganisms.Known disinfectant "Vilain" (Patent of Russian Federation N 1522498, A 61 L 2/16 from 09.03.94 year).The disadvantage of this tool is malorastvorima it in the water. Therefore, in practice, it found use as a disinfectant. In addition, it is not disinfects the air and light during long-term storage (more than three months) is oxidized, reducing their activity.The closest in technical essence is a composition for aerosol spray comprising a polymeric organic substance - acetylcellulose and polyvinyl butyral or metropolitenu resin, monatomic limit alcohol is ethyl or isopropyl, antifoam higher alcohol, an organic acid is acetic acid, the propellant - fluorocarbons or a mixture of propane-butane (1:4), and optionally phosphoric or nitric acid.This composition is used for the decontamination of surfaces contaminated and - active radionuclides.with. N 967067, C 09 K 3/30, 23.01.93 year).The disadvantage of the prototype is the lack of disinfectant action, because no part of the active-acting bactericidal additives.The objective of the invention is the creation of aerosol hazardous composition with a high disinfectant is more time.This task is solved in that the spray means comprising an organic polymer substance, ethanol and the propellant as the polymeric organic substance contains a copolymer of vinylpyrrolidone with vinyl acetate content of the first component 30 wt.% (resin SWAP-3) and an additional bactericidal additive - 2-methyl-5-di(trifluoromethyl)oxymethylene (vilain) in the following ratio, wt.%:
Vilain - 4,0-5,0
Resin SWAP-3 - 0,25-1,5
Propellant - 20-50
Ethyl alcohol - the Rest.In paragraph 2 of the claims indicates that the tool as a propellant contains (DICHLORODIFLUOROMETHANE) (Halocarbon 12) or a mixture of Halocarbon 12 and trichloromethane(halon 11) in the ratio of 1: 1 or liquefied hydrocarbon gas cleared.In table. 1 shows examples of formulations of aerosol disinfectant.Examples: source, 1, 5, and 6 are outside the claimed range of values of the components. Examples: 2, 3, 4 lie in the claimed values of components.As bactericidal additives to create a high disinfecting effect in the tool entered vilain in the amount of 4.0 to 5.0%, with a pronounced inhibitory effect on shirou 4.0 wt.% does not provide specified bactericidal action. Introduction vilayna above the upper limit of 5.0 wt. % does not lead to increased bactericidal action and is economically unjustified.As polymeric organic substances introduced resin SWAP-3 (50% alcoholic solution) 0.25 to 1.5 wt.%, consisting of a copolymer of vinyl acetate with vinylpyrrolidone. Designed for fixing vilayna on the treated surface and prevent rapid evaporation.Introduction resin SWAP-3 less than 0.25 wt.% leads to reduction of the disinfecting effect and increase the ratio of processing to achieve the same result.Introduction resin SWAP-3 more than 1.5 wt.% does not increase the disinfecting action, leads to the creation on the film surface.As the propellant used: refrigerant 12 (fluorocarbons), or a mixture of freon 12 and 11 (Trichlorofluoromethane) in a mass ratio of 1:1, grade a or liquefied hydrocarbon gas cleared, which is a mixture of propane, butane and isobutane in a certain ratio grades B and C.The introduction of the propellant is less than 20 wt.% causes atomized spraying of funds, insufficient disinfects the air, leads to excessive funds. The introduction of PR is an aerosol container by increasing the dose of inert propellant.Ethyl alcohol in the tool acts as a solvent vilayna and resin SWAP-3, at the same time enhances the disinfecting action viagina. The amount of ethanol is determined by the number of other components in the specified range of values.Example 1 preparation of aerosol disinfectant "Vilag-2".At room temperature the resin SWAP-3 add ethanol, stirred until a homogeneous solution. Then enter vilain and stirred until complete averaging of the mixture. With the help of dosing or measuring Cup the calculated dose of the mixture is poured into a metal aerosol container, sealcoat on the neck valve with siphon tube. Then in the aerosol container through the dispenser injected propellant, then set the spray head and wears a cap.Examples 2 to 6 are prepared analogously to example 1. The number of components in the composition shown in table. 1.In the patent and scientific literature by the applicant is not detected aerosol tool which includes vilain, resin SWAP-3, propellant (Halocarbon 12, a mixture of freon 12 and 11 (1:1) and liquefied hydrocarbon gas purged), ethyl alcohol and to the and have an "inventive step".Components disinfectant aerosol funds are available and cheap substances produced by the domestic industry, therefore the proposed composition is "industrially applicable".The study disinfectant properties of the drug was carried out according to common methods (instructions for determining bactericidal properties of new disinfectants N 739-68, 71 in the modification of the all-Russian scientific research Institute of preventive toxicology and disinfection, Moscow) with the use of conditionally pathogenic microorganisms: Escherichia coli, 1257; Staphylococcus aureus, 906.For cultivation of microorganisms and experiments used mastopathy agar, serum broth. Daily test culture evenly distributed across the surface of the model test surfaces (glass, tile, enamel, linoleum, painted wood). Used the tool "Vilag-2 was sprayed from an aerosol can from a distance of 20-25 cm to full hydration. After a certain exposure (single treatment - 30 minutes) the surface was wiped with sterile towels (5x5), which are then immersed in 20% serum broth (SB). Petri dishes with the crops of the SAT was placed on 24-48 hours thermo the results presented in table 2.Table 2 shows that the processing tool "Vilag-2" provided disinfection test the surface of the tile infected cultures of Escherichia coli and Staphylococcus aureus from about 99.9 to 100%, in the claimed range of values (range 2-4) at exposure 30 minutesMost high disinfecting effect from 4 types of funds (percentage of disinfection amounted to 100.0%). Reduction of resin, vilayna and propellant below the lower limit (option 1) leads to a decrease in the percentage of disinfection with up to 99.91 per 93,51%. Increasing the amount of propellant at a constant value vilayna and resin (option 5) leads to a decrease in the percentage of disinfection with 100,0 up 99,94%, in connection with the deterioration of the treatment on the treated surface. The increase in the number vilayna and resin above the upper limit (option 6) when 100,0% decontamination of surfaces economically unfounded, because the same effect is achieved when the values of the components at the upper limit of the claimed range.The original version, not containing vilain, obezzarazhivatel surface only 57.2% (against E. coli) and 42.0% (in respect of St. aureus), i.e. 2 times inferior in activity means "Vilag-2".Based on the obtained data 4 varial, linoleum, glass). A benchmark comparison served as chloramine, which was similarly Villagio put into the container with propellant and alcohol and investigated in aerosol form (5% bleach).The results of the tests are presented in table. 3. Studies have shown that the "Vilag-2" at one surface treatment of wood, enamel, tiles, glass ensures the destruction of vegetative forms of bacteria from 98,6 to 99,92%, and the benchmark comparison - chloramine from 60,0 up to 81%. With double the processing of infected surfaces the percentage of disinfection for "Vilag-2" amounted to 99.99 100.0% of cases, for chloramine 99,7-of 99.85%.Thus, the inventive tool is more active than the standard of comparison as single and double handling.Comparative results for the disinfection of surfaces, infected culture St. aureus by aerosol spray means "Vilag-2 and hydrogen peroxide (see table. 4).The effectiveness of disinfection in the treatment of air in areas considered to reduce the test microbes deposited on the test surface. Contaminated test surfaces were placed in different points in space at different levels from the floor. Exposure Tskitishvili-2" was 20-25 ml/m3, 10% hydrogen peroxide - 180-200 ml/m3.From table. 4 shows that the use of Vilag-2" spray method at exposure 30 min resulted in complete decontamination of bacterial microflora (St. aureus). The efficiency of disinfection of surfaces from tile, wood, glass, plastics amounted to 100%. The hydrogen peroxide provided obezzarazhennye 100% only surfaces of wood and glass.Disinfection of the premises, the infected culture of Staphylococcus aureus was achieved 20% solution of formaldehyde at a dose of 60 ml/m3or 12 g/m3at 12 hours of exposure.Comparing the experimental data from the literature shows that the flow of funds "Vilag-2" required for complete disinfection of surfaces, 3-8 times lower than the cost of hydrogen peroxide and formaldehyde to achieve the best results.In addition, work carried out on various types of equipment obstetric hospital (generic). As the test cultures were used saprophytic strains of Staphylococcus aureus and Escherichia coli with typical morphological and cultural properties. The test culture was applied on the surface (glass, linoleum, wood, metal, cafe is> the exposure time - 30 minutesAfter exposure were taken looking into the number 40 (20 on the determination of E. coli, 20 on the definition of St. saprophyticus). The method of inoculation and the results accepted.Were studied and virucidal activity of the proposed drug. As the test culture was used polio vaccine used for intake through the mouth. Application of the test culture on the surface, processing the drug, taking swabs similar to the previous paragraph.Selection of culture poliovirus was performed by the classical method in Virology laboratory for cell culture ner-2. The results of the experiments are presented in table. 5.From table. 5 shows that the disinfectant "Vilag-2" leads to a complete decontamination of the microflora of various types of equipment, made of glass, linoleum, wood, metal, tile, i.e. the efficiency of disinfection was 100% in the presence of controls 1104to 9,7104microbial cells on the test object.Results antiviral activity funds "Vilag-2" on the surface of the generic equipment showed no cytopathogenic effect and CLASS="ptx2">Aerosol disinfectant "Vilag-2" is a product of hazard class 4. His LD50for laboratory animals albino rats is greater than 5000 mg/kg the product has no locally irritant, allergenic, sensitizing action, has no inhalation effects on a living organism.Similar in action - sanitizer "Vilain is a toxic substance, its LD50-250 mg/kgComparing the data on the toxicity shows that the lethal dose of the "Vilag-2", causing the death of 50% of laboratory animals, exceeds that vilayna 20 times. Aerosol disinfectant "Vilag-2 is less toxic than similar action "Vilain".Thus, there are aerosol disinfectant "Vilag-2" refers to the 4th class of hazard, highly effective against bacterial and viral infections for the disinfection of air, surfaces, medical institutions, slightly irritating to mucous membranes and does not reduce its activity for a period exceeding one year. 1. Aerosol disinfectant, comprising an organic polymer substance, propellant, ethyl Sedona with a vinyl acetate content of the first component 30 wt.% (resin SWAP-3) and an additional bactericidal additive 2-methyl-5-di (trifluoromethyl)oxymethylene (Vilain), in the following ratio of components, wt.%:
2-Methyl-5-di(trifluoromethyl)oxymethylene - 4,0 - 5,0
Copolymer of vinylpyrrolidone with vinyl acetate content of the first component 30 wt.% - 0,25 - 1,5
Propellant - 20,0 - 50,0
Ethyl alcohol - Rest
2. Means under item 1, characterized in that as it contains propellant DICHLORODIFLUOROMETHANE (Halocarbon 12) or a mixture of DICHLORODIFLUOROMETHANE (Halocarbon 12) and trichloromethane (Halocarbon 11) at a ratio of 1:1 or liquefied hydrocarbon gas is purified.
SUBSTANCE: bactericidal agent contains, wt %: iodine 35-40, potassium nitrate 35-40, copper chloride 3-5, and carbohydrates - the balance.
EFFECT: enhanced efficiency of disinfection of veterinary surveillance objects by 20-40% and weakened fire risk of treatments.
FIELD: domestic plumbing installations, methods for disinfection thereof, particularly for large reservoirs.
SUBSTANCE: method involves applying disinfectant on installation surface and flushing installation with fresh water after disinfection operation finishing. Disinfection is performed by aerosol treatment carried out by accelerating anolyte particles up to speed of not less than 100 m/c. Anolyte with active chlorine concentration of not less than 100 mg/dm3 taken in amount of not less than 200 ml per 1 m2 of installation surface area is used as the disinfectant. Anolyte is used as aerosol with dispersity up to 100 microns and residence time of disinfectant on installation surfaces is not less than 30 min at positive temperature. Anolyte is sprayed by nozzle, centrifugal aerosol generator or high-pressure pump.
EFFECT: increased disinfection quality along with keeping ecological rules related to installation treatment and staff safety, increased depth of disinfectant penetration in installation surface and prevention of installation damage.
4 cl, 3 ex
FIELD: disinfection and sterilization of medicinal objects such as surgical and dental instruments, and also articles used in cosmetic rooms and hairdresser's shops.
SUBSTANCE: apparatus, according to first version, has chamber for receiving of objects, electromagnetic radiation source and device for feeding of atomized reactant into said chamber, reflector made in the form of paraboloid of rotation equipped with axial inlet aperture and mirror member having spherical reflecting surface. One wall of chamber is made from optically transparent material. Reflector is joined with chamber at its side adjoining transparent wall. Mirror member is mounted within region of focusing of reflector. Electromagnetic radiation source has successively arranged pulsed quantum generator and collimator which are optically joined through reflector inlet window, spherical surface of mirror member and reflecting surface of reflector with chamber wall distal from reflector inlet window. Apparatus, according to second version, has chamber for receiving of objects, at least one wall of chamber being made flat, electromagnetic radiation source made in the form of elongated pulse lamp, device for feeding atomized reactant into chamber, and mirror plate with one-sided optical transparence for electromagnetic radiation wave band of pulse lamp. Other side wall of chamber opposed to flat wall is made trough-shaped, with internal reflecting surface and parabolic cross section. Pulse lamp is located along focal axis of trough parabola. Mirror plate is mounted between flat side wall of chamber and pulse lamp and directed with its optically transparent side toward pulse lamp. Pulse lamp is optically joined through reflecting surface of side wall of trough-shaped chamber, mirror plate with one-sided optical transparency and internal surface of flat side wall of chamber with mirror side of mirror plate.
EFFECT: enhanced reliability in operation and convenient usage of apparatus for disinfecting and sterilizing of objects.
11 cl, 3 dwg
FIELD: environmental protection.
SUBSTANCE: invention relates to means and methods of integrated degassing, disinfection, and shielding of sites and zones, where presence of high-activity poisonous substances, poison-gases, chemical weapons, pathogenic microorganisms, their vital activity toxic products, insects (including carriers of human and animal diseases), radioactive substances are revealed or suspected, and also to means and methods to extinguish burning of inflammable liquids and to prevent in inflammation of spills of inflammable liquids. Multifunctional foam composition of invention includes, as active substance, 0.1-5% of didecyldimethylammonium halide clatrate with urea. Use of indicated clatrate provides simultaneous effect of foam compositions, wherein clatrate acts both as multifunctional active substance and as foaming agent. Invention can further be used to eliminate consequences of use of weapons of mass destruction and to eliminate consequences of man-made accidents and emergency situations.
EFFECT: expanded protection possibilities.
24 cl, 3 tbl, 6 ex
FIELD: disinfection and sterilization of medical designation objects such as complex-shape tools for surgery, stomatology, tubular members and articles such as endoscopes, laparoscopes, catheters and so on objects including thermolabile articles.
SUBSTANCE: apparatus for disinfecting and sterilizing includes chamber whose inner surface reflects UV -irradiation; pulse UV-lamps arranged inside chamber in quartz tubes by rows (at least two lamps in each row); latticed trays for treated objects; electric power source connected through high-voltage conductors with pulse UV-lamps; automatic control unit made with possibility for setting repetition frequency of high-voltage pulses of power source; device for spraying antiseptic matter. Said device is communicated through pipelines with antiseptic matter sprayers mounted on inner surface of chamber in such a way that aerosol provided by them in chamber may perform vortex motions. Sterilized ozonated air created by cooling of pulse lamps is fed inside working chamber. Biologically active aerosol-gas mixture generated at sterilization process is pumped through inner cavities of treated object.
EFFECT: shortened time period for sterilizing and disinfecting, possibility for treating complex-shape objects with deep cavities and tubular objects.
4 cl, 1 dwg
SUBSTANCE: invention relates to field of medicine and sanitation, and can be used for disinfection in medical-prophylactic institutions of different type, units of communal services, on any transport. Disinfectant, includes polymeric organic substance, bactericidal additive - 2-methyl-5-[di(trifluorinemethyl)oximethyl]furane and ethanol, as polymeric organic substance it contains 50% water solution of vinyl pyrrolidone copolymer with vinyl acetate, with definite component ratio.
EFFECT: invention allows saving high disinfecting properties of means during 26 months, is highly efficient against bacterial (including tuberculosis bacteria), viral infections, pathogenic fungi and belongs to low-hazard substances.
5 tbl, 4 ex
SUBSTANCE: pyrotechnic composition for obtaining of didecyldimethylammonium halogenide aerosol contains didecyldimethylammonium halogenide or its clathrate with urea as active substance and the thermic composition providing the sublimation of the active substance during combustion. The invention refers also to the fume-forming pyrotechnic article, to the method for disinfection and/or disinfection of the objects as well as to the method for protection of the objects from biological damage at storage.
EFFECT: efficient disinfection and disinfection, protection of the objects from biological damage at storage together with low consumption of the active substance and low aerosol toxicity.
38 cl, 1 dwg
FIELD: mechanics, chemistry.
SUBSTANCE: invention relates to aerosol disinfection of structures intended for production, treatment, storage and transportation of agricultural products and foodstuffs, for disinfection of raw stock, feed, semi-finished products and finished products at all stages of their production, treatment, storage and transportation. It may also be used for antibioticotherapia of animals and maintaining microclimate in veterinary inspection premises, hothouses and storerooms. To this end, the proposed sprayer comprises a tight inner fluid chamber with metered fluid channels coming out radially therefrom in horizontal plane. One of the plates features metered slots in face wall aligned with the said metered channels to form spraying nozzles. The said nozzles are arranged regularly or segmented along circumference, and feature geometrical dimensions that allow the disifectant water solution aerosol to have optimum mean-median dispersity of 5 to 24 mcm, required for industrial large-scale disinfection, and a portion of the said fraction in fluid volume making up to 95%, when connected to standard industrial compressors for forced fluid feed. The proposed sprayers make a component of the new flexible industrial disinfection system.
EFFECT: reduced consumption of disinfectants, lower costs of disinfection, reduced labour input.
2 cl, 7 dwg
SUBSTANCE: invention refers to disinfection of materials and spaces and can be used in agriculture, medicine, veterinary science, textile and construction industry, and also in analogous industries. The method of disinfection consists in dispersion of a disinfectant presented with mixed air and electrically activated solution in the weight relation (3-10): 1 with drop size of the electrically activated solution less than 10 mcm. Said mixture is prepared by ejector with following separation of coarse particles.
EFFECT: invention allows essentially improving quality of disinfection, using in aerosolisation the electrically activated solution, continuously stored in a liquid state, without aerosol activity loss and also forming an aerosol active within at least 4 hours and available for processing of various materials.
3 cl, 3 dwg, 14 tbl, 11 ex
FIELD: medicine, veterinary science.
SUBSTANCE: method of preventive treatment of animals and birds involves the generation of aerosol containing iodine compound particles of sizes adequate for distribution in the airways, differing that a solid-propellant composition containing potassium iodide, fuel, an oxidiser, processing aids are placed in the aerosol generator, the aerosol generator is arranged in the same room with animals or birds, to feed a heat pulse, to perform self-propagating high-temperature synthesis which results in producing solid potassium iodide particles of size 30-1280 nm; the animals or birds are exposed to the generated aerosol mixed gas and solid particles for 2 hours. The method uses carbon fuel as fuel, nitre as an oxidiser, paraffin or ceresin as processing aids.
EFFECT: invention provides decrease in labour input and higher safety of the method.
2 cl, 1 tbl
FIELD: temporary layout and differentiation of controlling distances on playgrounds and fields suitable for sport.
SUBSTANCE: foaming aqueous composition containing at least one non-ionic surfactant or amphoteric surfactant as foaming agent, and at least one amphoteric surfactant as foam control agent, is sprayed on playground or field. Said non-ionic surfactant represents ethoxylated vegetable oils; amphoteric surfactant as foaming agent represents alkyldimethylamine oxide; and amphoteric surfactant as foam control agent represents betaines in combination with at least one propellant. Composition of present invention is useful in layout and differentiation of controlling distances on playgrounds and fields, in particular football fields.
EFFECT: method with improved effectiveness.
19 cl, 3 ex
SUBSTANCE: liquid for forming aerosol which is used as a solution of aromatic substance contains basic components and adipic acid which is added to the basic components. The basic components include a solvent and a lipophilic aromatic substance containing L-menthol dissolved in the solvent. The solvent is propylene glycol.
EFFECT: use of the liquid enables formation of a significant amount of aromatic aerosol, having long life.
4 cl, 2 dwg, 2 tbl, 6 ex
SUBSTANCE: method of producing hydrocarbon propellants involves combined drying and cleaning of hydrocarbon material and separating the hydrocarbon propellant composition. The hydrocarbon material used is propane, a butane fraction or isobutane or n-butane or propane or a mixture of propane and n-butane. Drying and cleaning is carried out by passing the material in liquid-phase through sorbents in three series-arranged adsorbers. The first adsorber on the process path is filled with aluminium oxide, the second adsorber is filled with zeolite NaA and the third adsorber is filled with zeolite NaX. The given propellant composition is obtained after the third adsorber, wherein if the hydrocarbon material used is a mixture of propane and n-butane, the given propellant composition is obtained in a mixer by mixing propane and n-butane in weight ratio of 0.96.
EFFECT: obtaining a product of high quality with low content of moisture and sulphur compounds, low operational and capital costs on implementing the process.
2 dwg, 1 tbl
SUBSTANCE: method of drying and purifying hydrocarbon propellants involves combined deep drying and purification of hydrocarbon material, which is carried out by passing a liquid-phase mixture through sorbents in three series-arranged adsorbers. The first adsorber on the process path is filled with aluminium oxide, the second adsorber is filled with aluminium oxide or zeolite NaA and the third adsorber is filled with zeolite NaX or zeolite CaA or zeolite CaX.
EFFECT: obtaining a product of high quality with low content of moisture and sulphur compounds, low operational and capital costs on carrying out the process.
1 tbl, 1 dwg
SUBSTANCE: invention relates to heat-transfer compositions, applied in cooling systems and heat-transfer devices. Heat-transfer composition contains trans-1,3,3,3-tetrafluoropropene (R-1234ze(E)), difluoromethane (R-32) and 1,1-difluoroethane (R-152a) as coolants.
EFFECT: claimed heat-transfer composition possesses combination of improved properties of productivity of cooling and mixability with lubricating materials with low inflammability and low global warming potential (GWP) in comparison with separate coolant and known heat-transfer compositions and makes it possible to replace existing coolants, possessing considerable GWP.
54 cl, 5 dwg, 45 tbl
SUBSTANCE: invention relates to heat-transmitting composition, containing E-1,3,3,3-tetrafluoroprop-1-ene (R1234ze(E)), 3,3,3 trifluoropropene (R-1243zf) and difluoromethane (R32). Described is application of said composition in heat exchanger, in formulation of foamed composition, dispersed composition, for cooling or heating product, in methods of purification or extraction of materials, reduction of impact on the environment produced by product of existing coolant exploitation.
EFFECT: composition possesses improved characteristics of cooling at lower fire hazard and reduced value of global warming potential and can be suitable for replacement of existing cooling agents, in which said indices are lower.
48 cl, 9 tbl
SUBSTANCE: invention relates to compositions, containing 2,3,3,3-tetrafluoropropene, and their application as liquid heat carriers, extension agents, solvents and aerosols. Composition contains from 15 to 50 wt % of 2,3,3,3-tetrafluoropropene, from 5 to 40 wt % of from 5 to 40 wt % of HFC-134a and from 45 to 60 wt %, preferably from 45 to 50 wt %, of HFC-32.
EFFECT: claimed composition has critical temperature higher than 87°C, temperature at compressor output, equivalent for R-410A, and can replace R-410A without changing technology, used in compressors.
10 cl, 2 tbl