For the treatment of chronic prostatitis

 

(57) Abstract:

The invention relates to medicine, namely to facilities for the treatment of chronic inflammatory diseases of the prostate. The tool is made in the form of suppositories and contains the lipophilic fraction of the pulp of fruits of Aronia melanocarpa (7-20 wt. %) and lipophilic suppozitornyj basis to 100. The tool has anti-inflammatory and analgesic activity. The use of this tool leads to a reduction in treatment time. table 1.

The invention relates to medicine, in particular to the means for the treatment of chronic inflammatory diseases of the prostate.

Know the use for the treatment of chronic prostatitis non-steroidal anti-inflammatory drugs, i.e. indomethacin (1). Indometacin assign inside depending on tolerability in a daily dose of 100-150 mg (3-4 hours) or in the form of rectal suppositories 0.05 grams per day.

Disadvantages of treatment with indomethacin is a need for long-term treatment with the drug, because of premature discontinuation may lead to the resumption of the pain; the possibility of adverse reactions. In particular, indomethaci the applicatio for the treatment of chronic inflammatory diseases of the prostate (2) rectal suppositories weighing 0.5-1.0 g, prepared on the basis of sea-buckthorn oil and containing the herb celandine, the fruit of Sophora japonica flowers chamomile. Candles were introduced into the rectum daily for a period of 10-15 weeks, with the first two candles were introduced in the morning, and the third candle is 10-14 hours First and last 3-5 weeks first and second candles were introduced after prostate massage.

The disadvantages of this tool are the duration of the treatment, as well as the complexity of the treatment process.

An object of the invention is the reduction of treatment time.

This goal is achieved using rectal suppositories based on lipid complex of the pulp of the fruit Aronia entered 2 times a day for 10-12 days.

Candles were prepared by the method of pouring suppozitornyj mass consisting of suppozitornoj base (cocoa butter) and lipophilic fractions of the pulp of the fruit Aronia obtained by degreasing plant materials are crushed to the size of particles passing through a sieve with the hole diameter of 2 mm food grade gasoline "Nevrax in the ratio of raw materials extractant 1:10 for 6 h followed by distillation of the solvent, the ratio of the basics and lipophilic fractions of 3:1, the Holy mass is spetsificheskoi etiology, patient age from 20 to 55 years.

Criteria for diagnosis and evaluation of treatment effectiveness have served the objective of the study, hematological and immunological tests, urine tests, secrets of the prostate gland and semen, bacteriological tests, and the results of ultrasonic, radiographic and endoscopic studies.

The control group consisted of 20 patients, nearly identical in structure with the main group, in the course of therapy, which was administered antibacterial drugs, biogenic stimulators, physical therapy, local procedures, comprehensive treatment preclude the use of any rectal suppositories.

The course of treatment in the main group included the introduction of one rectal suppository containing 7-20% (0.2 to 0.6 g) lipid complex of the pulp of the fruit Aronia, 2 times a day for 10 days.

All patients tested drug is well tolerated. In any case, clinically or laboratory does not identify any local or General adverse reactions or complications. At the same time revealed therapeutic activity of subjects of candles in chronic prostatitis, in particular their anti-inflammatory and analgesic Affinia pain and dysuria, the reduction or complete data normalization objective research, laboratory, ultrasound and endoscopic tests.

Example 1. Patient R. , aged 26. Diagnosis: chronic bacterial (non-specific) urethritis, chronic lung prostate in the phase of active inflammation. The disease duration of 5 years. Previously held courses of standard therapy is ineffective. The hospital completed a course of therapy with the use of candles containing 0.2 g (7%) of lipophilic fraction of the pulp of the fruit Aronia, 1 candle 2 times in 12 days. At follow-up was marked by almost complete disappearance of pain and dysuria, improving data palpation of the prostate and ultrasound data normalization of urine and prostate secretion.

Example 2. Patient L., 42 years. Diagnosis: chronic antibacterial parenchymal prostatitis in remission with pronounced symptoms of pelvic sympathalgias. The disease lasts 8 years, the clinical picture was dominated by complaints of pain and paresthesia in the area of the perineum and rectum. The treatment included subjects candles containing 0.6 g (20%) of lipophilic fraction of the pulp of the fruit Aronia, 1 candle 2 times within 10 days. During the control study Hotmail dynamics (table).

Thus candles containing lipid complex of the pulp of the fruits of Aronia in the number of 7-20% (0.2 to 0.6 g), have obvious therapeutic effect on chronic nonspecific prostatitis. They are safe, easy to use. The proposed facility compared to the prototype allows to reduce the treatment time from 3.5 months to 10 to 12 days, as well as to simplify the process of treatment.

The list of references.

1. Vorobyov A. I. Reference practitioner, M, Medicine: 1982, S. 515.

2. Mashkovsky M. D. Medicines. M: Medicine: 1987, T. 1, S. 199-200.

For the treatment of chronic prostatitis, containing lipophilic suppozitornyj based and active ingredient of natural origin, characterized in that the active substance use lipophilic fraction of the pulp of the fruits of Aronia in the following ratio, wt.%:

Lipophilic fraction of the pulp of the fruit Aronia - 7 - 20

Lipophilic suppozitornyj the basis of up to 100:

 

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