(57) Abstract:Dezinficiruy detergent is intended for disinfection of surfaces in premises, sanitary-technical equipment, linen, crockery, medical products. The tool contains a peroxide, lauryl sulfate, magnesium, glycerin, sodium oleate, disodium salt EDUC (Trilon B), sodium benzoate and water at a ratio of components. The invention relates to medicine, namely dezinficiruy-detergents intended for disinfection of surfaces in premises, sanitary-technical equipment, linens, Housewares, medical devices, and for sterilization of medical products.Known disinfectant based on hydrogen peroxide.For example, it is known disinfectant, representing a brown liquid containing hydrogen peroxide, chinosol, sulfinol and water (ed. St. USSR N 1487908, class A 61 L 2/16, 1987).However, this disinfectant has low storage stability, leading to increased toxicity and reduced bactericidal activity of the solutions, the subsequent bleaching.To address some of the deficiencies in the composition of the disinfectant, hydrogen peroxide, enter the stabilizer, for example, sodium benzoate (see parkhach M. E., Pankratova, P., Sokolova N. F. Technical aspects of creating dosage forms. M., 1986, T. 24 New stabilizer 3% hydrogen peroxide, S. 54-60) in the following ratio of components: hydrogen peroxide 3%, sodium benzoate 0.05% of water.This technical solution to the technical essence and the achieved result is the closest to the claimed technical solution and, therefore, selected as a prototype.Introduction as a stabilizer in disinfectant - prototype sodium benzoate increases the stability of the solution, but still not achieved bactericidal activity of the drug, the economic use of hydrogen peroxide and reducing corrosion activity.The task of the invention is to increase bactericidal activity, the economic use of hydrogen peroxide and reducing corrosion activity.This object is achieved in that dezinficiruy detergent, hydrogen peroxide, sodium benzoate, water, soglasnogo B) in the following ratio of components, wt.%:
The peroxide - 30,0
Valium magnesium - 6,0
Sodium benzoate - 1,0
The disodium salt of DATUK (Trilon B) - 1,0
Glycerin - 1,0
The sodium oleate - 1,0
Distilled water - the Rest.The proposed composition contains an additional stabilizer - disodium salt EDUC (Trilon B), which not only improves the stability of the solution, but at the same time is sequestrants (water softener), as besieging salts of calcium and magnesium.In connection with the widespread use of hydrogen peroxide for the purpose of disinfection is of interest to reduce the concentration of working solutions that will lead to the saving of the original product and will bring some economic effect.Reduction of hydrogen peroxide can be achieved by the addition of surfactants, such as lauryl sulfate, magnesium.Introduced in the formulation of detergent - valium magnesium inventive composition acquires and detergent properties.Conducted Toxicological and hygienic assessment of this detergent and its residues after sterilization processing of medical instruments.Conducted issledowatelej quantities with medical instruments. Studied detergent in the claimed composition is recommended for use in health care institutions.In addition, one should also consider the safety of personnel working with dezinficiruy-detergent (preparation of solutions, soaking, washing and rinsing products and other operations).Offer dezinficiruy detergent is harmless and has no sensitizing effect when applied externally, as in the formulation of the inventive composition is introduced glycerin.The proposed solution has a broad spectrum of antimicrobial activity and can be used for disinfection in health care facilities in intestinal and drip infections of bacterial and viral etiology, ringworm, tuberculosis, especially dangerous infections (plague, cholera, melodos), anthrax in concentrations of 1-6% hydrogen peroxide.Introduced in the formulation of the corrosion inhibitor is sodium oleate, this dezinficiruy-detergent may be recommended for use in sterilization processing of medical products, as it does not corrode metals, does not spoil the glass and plasty composition dezinficiruy-detergent differs from the known to the introduction of new components, namely lauryl sulfate, magnesium disodium salt EDUC (Trilon B), glycerin, sodium oleate.Thus, the proposed solution meets the criterion of "Novelty".Conducted patent research failed to reveal solutions that had all the hallmarks of the present invention, suggesting that the criterion of "inventive step".The proposed solution also meets the criterion of "industrial applicability" because it can be widely used in many fields of engineering.A concentrated solution of hydrogen peroxide are placed in a reactor equipped with a mechanical stirrer.Then dissolved in water, sodium benzoate, disodium salt EDUC (Trilon B), sodium oleate, glycerine. The obtained salt is added to concentrated hydrogen peroxide solution and stirred for 40 minutesAfter this solution adds valium magnesium and stirred for 50 minutesFor preparation of working solution in concentrations of 1-6% hydrogen peroxide, the resulting composition is diluted with water 1/10 - 1/50.The tool is designed to desipte medical products.Medical devices contaminated with blood, soaked for 60 minutes in dezinficiruy-detergent, and then wash in the same solution for 1 to 2 minutesWe studied the toxicity of the proposed dezinficiruy-detergent. The parameters of acute toxicity when injected into the stomach dezinficiruy-detergent refers to moderately toxic compounds III hazard class. Median lethal dose of 3000 mg/kg, but compared to the toxicity of its components hydrogen peroxide (median lethal dose of 2000 mg/kg) is less toxic in 1,5 times and valium magnesium (median lethal dose of 5000 mg/kg 2 times less toxic than the claimed means.When applied to the skin of a working solution dezinficiruy-detergent at a concentration of 1-6% hydrogen peroxide in amounts of 2.5 g/kg was observed only irritant action, and clinical signs and death of animals was absent, indicating low toxicity of funds.Thus, the claimed dezinficiruy detergent in use valium magnesium disodium salt EDUC (Trilon B), glycerol and oleate sodium provides:
- increase stabilnosti concentrations and fewer, which leads to the saving of the original product and gives a certain economic effect;
- reduction of corrosiveness;
- reduction of toxicity. Dezinficiruy detergent, hydrogen peroxide, sodium benzoate, water, characterized in that it further comprises valium magnesium, glycerin, sodium oleate, disodium salt EDUC (Trilon B) in the following ratio, wt.%:
The hydrogen peroxide - 30
Valium magnesium - 6
Sodium benzoate - 1
The disodium salt of EDUC (Trilon B) - 1
Glycerol - 1
The sodium oleate - 1
Distilled water - Ostalnoe
FIELD: veterinary sanitation.
SUBSTANCE: in the suggested disinfectant one should dissolve electrochemically activated neutral anolyte, containing 0.6 mg/ml active chlorine, with running water at 1:5 ratio and the composition of diluted electrochemically activated neutral anolyte should be supplemented with 1-1.5 mg acetic acid per 1 ml preparation. The innovation enables to decrease the concentration of active chlorine and energy expenses at keeping initial high bactericidal activity of electrochemically activated neutral anolyte and, also, apply it in aerosol form for air sanitation in poultry-breeding housings when poultry is present.
EFFECT: higher efficiency of disinfection.
FIELD: veterinary science, veterinary disinfection.
SUBSTANCE: the suggested disinfectant should be applied for sanitation of animal and poultry objects. It contains acetic acid, sodium monochloroacetate, sodium dichloroacetate, sodium acetate, sodium glycolate, sodium chloride and water at their certain ratio. At concentration of 0.3-1.0% at exposure of 3 h this preparation causes 100% lethality in sanitary-representative microorganisms.
EFFECT: higher efficiency of disinfection.
2 ex, 1 tbl
FIELD: medicine, in particular disinfectant for domestic and industrial compartments, surfaces, tools, transport.
SUBSTANCE: claimed composition contains mixture of tetramethylenediethylene tetramine with silver ninrate, stabilizer and silica gel. Tetramethylenediethylene tetramine is obtained by reaction of at 50-70°C for 60-80 min in absence of alkali, then formed solution is cooled to 18-20°C for 12-18 h.
EFFECT: disinfectant with improved quality, higher bactericide and virulicide action; method with increased yield.
2 cl, 4 tbl, 6 ex
FIELD: medicine, hygiene.
SUBSTANCE: invention relates to a disinfecting agent. Interpolymeric agent comprises the following ratio of components, wt.-%: polyguanidine base, 0.3-0.5; chlorine-containing polymer, 3.1-4.0; ethyl alcohol, 7-10; nefras, the balance. Polyalkylene guanidine base or polyoxyalkylene guanidine, or polyalkylene biguanide is used as a polyguanidine base. Mixture of chlorosulfonated polyethylene with chlorinated polyvinyl chloride taken in the ratio = (7.3-10.1):1 is used as a chlorine-containing polymer. Agent can be used for preventive prolonged disinfection in compartment with many people amount, for example, in medicine institutions, in objects of criminal-executive system, evacuation points, in apartments for culture-domestic aims, in homes, veterinary, food branch, trade, transport. Invention provides enhancing strengthening indices of polymeric cover and to expand field of its applying.
EFFECT: valuable properties of agent.
4 cl, 6 tbl, 14 ex
FIELD: chemical technology.
SUBSTANCE: invention relates to a method for preparing disinfecting agent as derivative of polyhexamethylene guanidine. Method involves thermal polycondensation reaction of hexamethylenediamine and guanidine hydrochloride for two stages. At the first stage hexamethylenediamine is added to guanidine hydrochloride melt up to the molar ratio = 1:1 and mixture is subjected for control thermostatically up to ceasing ammonia evolving. At the second stage hexamethylenediamine excess is added to formed melt of polyhexamethylene guanidine chloride that is taken as measured its molar ratio with guanidine hydrochloride = 2:n wherein n means degree of polymerization that is calculated based on molecular mass of terminal groups of polyhexamethylene guanidine derivative obtained at the first stage by the following formula: n = [%Cl]*Mk/(35.45-[%Cl]*177.678) wherein %Cl means the relative content of chlorine by mass in derivative of polyhexamethylene guanidine; Mk means molecular mass of terminal groups of polyhexamethylene guanidine derivative and at Mk = 17.034 the relative content of Cl is determined in reaction mixture before addition of hexamethylenediamine excess, and at Mk = 215.382 the relative content of Cl is calculated in the composite of polyhexamethylene guanidine derivative formed at the second stage. Then the reaction mixture is subjected for control thermostatically at temperature 165-200°C up to ceasing ammonia evolving. The end product is prepared as polymer-analog of polyhexamethylene guanidine chloride. Invention provides reducing yield of the end product in water-insoluble fraction and to enhance bactericidal activity of disinfecting agent. Invention can be used in medicine and veterinary science, in treatment of natural and sewage waters, in processes for leather and fur tanning and in industrial and domestic conditions wherein bactericidal preparations are required.
EFFECT: improved preparing method.
1 tbl, 2 ex
SUBSTANCE: invention relates to a disinfecting agent involving ethyl alcohol and an active additive that comprises additionally acetaldehyde, diethyl phthalate and glycerol and/or propylene glycol in the following ratio of components, wt.-%: ethyl alcohol, 69-94; active additive as measured for the main substance 0.0004-0.12; acetaldehyde, 0.5-1.0; diethyl phthalate, 0.08-0.20; glycerol, 0.00-0.15, and/or propylene glycol, 0.00-0.0001, and water, the balance. The disinfecting agent comprises catamine AB or biopag D as an active additive as measure for the main substance in the amount 0.025-0.12, or benzyl benzoate (3-5 mg/l) and menthol (1-3 mg/l). The disinfecting agent can be used as a cutaneous antiseptic agent (in the presence of glycerol and/or propylene glycol as components) and disinfecting agent for treatment of surfaces. Invention provides the effective treatment of surfaces in infectious of bacterial, viral and fungal etiology. Agent doesn't irritate hand skin.
EFFECT: improved and valuable properties of agent.
FIELD: animal science.
SUBSTANCE: the present innovation deals with sanitary-hygienic preparation of exercising area, equipment and animals before sampling the sperm in breeding animals. One should clean the floor in exercising area with catholyte at pH being not less than 11.0 and redox potential - not less than -600 mV; air and floor in exercising area, special equipment for animals as service ramps, artificial vaginas and sperm-collecting reservoirs should be disinfected with anolyte at pH being not more than 2.5, redox potential - not less than 1100 mV and active chlorine content of not less than 0.03%; one should wash animals skin, scrotum and prepuce with anolyte at pH being 7.0±0.5 and redox potential of not less than 900 mV. Moreover, one should treat the air in exercising area with anolytic aerosol at liquid drops diameter being not more than 50 mcm at exposure of not less than 30 min, as for artificial vaginas and sperm-collecting reservoirs they should be kept in anolyte for 30-60 min. The innovation provides to obtain high-quality sperm in farm animals.
EFFECT: higher quality of disinfection.
FIELD: medicine, ophthalmology.
SUBSTANCE: invention proposes a composition for treatment and storage of soft contact lens that comprises cetyl pyridinium chloride, polyethylene oxide of molecular mass 400 Da, ethylenediaminetetraacetic acid disodium salt, sodium hydrogen phosphate dodecahydrate, sodium dihydrogen phosphate dihydrate and water taken in the definite ratios by wt.-%. Invention provides reducing toxicity and enhances disinfecting and clearing properties of composition used for treatment and storage of soft contact lens.
EFFECT: improved and valuable properties of composition.
2 tbl, 3 ex
SUBSTANCE: the suggested preparation contains the following components: o-phthalic aldehyde, non-ionogenic surface-active substance, benzotriasol and water (in weight%). As non-ionogenic surface- active substance one should apply either neonol or syntanol. To prepare this preparation one should, first, mix o-phthalic aldehyde with non-ionogenic surface-active substance and benzotriasol, the mixture obtained should be dissolved in water. The innovation could be applied for sterilization of medicinal products.
EFFECT: higher efficiency.
4 cl, 4 ex
FIELD: veterinary science.
SUBSTANCE: the suggested composition contains a certain salt of calcium hypochlorite as an oxidizing agent and, additionally, zeolite as an adsorbent at the following ratio of components, weight%: a certain salt of calcium hypochlorite 30.0-70.0, zeolite - the rest. Application of the composition suggested provides neutralization of animal skin under any environmental conditions, both at plus and minus environmental temperature values.
EFFECT: higher efficiency of application.
6 ex, 1 tbl