For the treatment of infectious diseases of lips

 

(57) Abstract:

The invention relates to medicine and can be used for the treatment of infectious diseases of the lips. The tool provides improved therapeutic effect, reducing treatment time and reduce the likelihood of recurrent infections of the lips. This is achieved by the fact that the product contains ion-exchange resin based on a copolymer of methyl acrylate with devicelevel ether of diethylene glycol with a particle size of 0.1 - 100 μm, polyvinyl alcohol, glycerin and water in the following ratio of initial components, wt.%: the ion-exchange resin based on a copolymer of methyl acrylate with devicelevel ether of diethylene glycol with a particle size of 0.1 - 100 μm of 7.6 to 13.8; polyvinyl alcohol 3,1 - 4,6; glycerin 6,3 - 9,2; water the rest. table 2.

The invention relates to medicine and can be used for the treatment of infectious diseases of the lips, angular lesions of the lips (Zayed), chronic cracks, herpes sores, eczema, infectious heylity etc.

Widely known as a means for the treatment of infectious diseases lips ointments and emulsions containing: antibiotics (for example, lincomycin, syntomycin), antibacterial drugs (inestrosa, Dec>/P>However, all these tools have a number of individual and General shortcomings, namely:

a) bactericidal activity of drugs for microorganisms causing infectious heylity, occurs selectively, therefore, a necessary pre-sowing and identification of microflora, which significantly delays the time of extraction;

b) antibiotics can lead to resistant to them forms of microorganisms. Hormones can cause cytotoxic effect;

C) drugs acting on microbial cells bakteriostaticheski and bactericidal, wound them not removed, and the remaining microflora can support inflammation and allergosorbent the body. With long-term use of medications, as well as in individuals with hypersensitivity to these drugs can develop peripheral neuritis, myelopathy. Drugs cannot change ourselves pH inflamed lips. Almost all drugs have a sensitizing effect.

Know the use of 2,4,6-triadically as antiviral agents, which has high activity against several strains of the herpes virus simple.

A disadvantage of the known tool is that p is skim the technical essence is a means for the treatment of diseases of the lips, for example, chronic fissures of the lips, which represents a gel of polyvinyl alcohol which is at body temperature quickly solidifies, forming a film on the lips, kept for several hours [5]

A disadvantage of the known tools is the length of time of treatment is about 1 to 2 weeks. it does not ensures complete deletion of the microflora on the surface of the lips that can support the inflammation.

An object of the invention is to increase therapeutic effect, reduction of terms of treatment of infectious diseases of the lips and reduce the likelihood of recurrence.

This task is achieved by the fact that known for the treatment of infectious diseases of the lips, containing polyvinyl alcohol and water, further comprises an ion-exchange resin based on a copolymer of methacrylate with devicelevel ether of diethylene glycol with a particle size of 0.1 to 100 μm and glycerin in the following ratio of initial components, wt.

The ion-exchange resin based on a copolymer of methyl acrylate with devicelevel ether of diethylene glycol with a size of 0.1 to 100 μm 7,6 13,8

Polyvinyl alcohol 3,1 4,6

Glycerin 6,3 9,2

Water the Rest

When the content of the ion exchange resin in quantities of the same effect and use of resins with different granulometric composition.

As the ion exchange resin is used, the carboxylic cation exchanger marks KB-2E, obtained on the basis of a copolymer of methyl acrylate with devicelevel ether of diethylene glycol. The cation exchange resin intended for the manufacture of ophthalmic therapeutic ion exchange liners, produced by STF 6-07-437-92 and has the following characteristics (table. 1).

The resin before cooking tools pre-crushed in the mill. For cooking means using the fraction with a particle size of 0.1 to 100 microns (dust fraction).

The tool is prepared by mixing until a homogeneous gel-like mass of the initial components of the composition according to one of the formulations shown in table. 2.

The resulting tool was used to treat patients L. 11 years, applied for about herpes heylita. Ill 3 days ago. First there was a burning sensation, then came the bubbles in the corner of the mouth and lips on the left. Applied topically oxolinic ointment, but no effect was observed. A similar disease on the lips with the patient was observed 3 to 4 times a year. Recovery usually occurred after 2 to 3 weeks, regardless of the type of funds used it for treatment. At the time of treatment to the doctor the patient suffered from pain when opening the mouth in the area of the glasses, in the line of closing the lips crack deep about one mm, a length of about 1 cm, with a strong opening mouth bleeding. The skin and mucosa around the lesion slightly swollen, palpation in the angle of the mouth on the left painful.

On a site of the lesion with a spatula put the proposed remedy that in a few minutes turns into a film. The film is kept on the lips for 4 to 5 hours, then disappears spontaneously, without causing any additional damage to the affected area of the lips. The procedure of drawing tools exercise 2 times a day. On the second day, the patient stopped the pain and itching, the swelling bubbles brown. The crack was reduced to 4 mm and disappeared completely after the second day of treatment. Total time from start of treatment until full recovery was 3 days. When observation of the child during the year of relapses were observed.

The proposed tool was tested on 35 patients heylity, including infectious 30 people, and eczematous 5 people.

Time to full recovery was 3 to 4 days, depending on the time of seeking medical attention from the onset, and severity of illness.

The proposed tool has high is rblu and destruction of lesion of microflora, containing the remains of dead organisms.

This leads to the high efficiency of the treatment and reduce treatment time 1.8 4.7 times compared to the prototype, with no recurrence during the observation of patients during the year. When monitoring patients within 2 years revealed reduction of relapse by 70%

For the treatment of infectious diseases of the lips, containing polyvinyl alcohol and water, characterized in that it further comprises an ion-exchange resin based on a copolymer of methyl acrylate with devicelevel ether of diethylene glycol with a particle size of 0.1 to 100 μm and glycerin in the following ratio of initial components, wt.

The ion-exchange resin based on a copolymer of methyl acrylate with devicelevel air diethylenglycol with a particle size of 0.1 to 100 μm 7,6 13,8

Polyvinyl alcohol 3,1 4,6

Glycerin 6,3 9,2

Water The Rest

 

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