Ointment "febronius" with antihyperuricemic activity
(57) Abstract:The invention relates to medicine, specifically to the drugs used for the treatment of hyperkeratosis treatment. Drug - ointment with antihyperuricemic activity contains glacial acetic acid, and the filler is a mixture of paraffin, anhydrous lanolin in a ratio of components, wt. %: glacial acetic acid 10 - 30; paraffin 19 - 30; lanolin - rest. The results feleciana 85 - 98 %. table 1. The invention relates to medicine, specifically to means with antihyperuricemic activity.Known means with antiaritmicheskoi activity. This corn liquid, corn plaster "Sliped". Their disadvantage is the instability of the keratolytic effect.The closest to the technical nature of the alleged invention is protivopozharnaya ointment of the following composition, including salicylic acid, boric acid and anhydrous lanolin 15; vaseline to 100. The disadvantage of it is the instability of the keratolytic effect that is due to the fact that therapeutic effect does not affect the metabolic processes in the skin.The aim of the invention is a medicinal product with Ehna layers, what a positive effect on metabolic processes in the skin.This goal is achieved drug ointment, treatment which is based on acetic acid.As a filler, a mixture of anhydrous lanolin and paraffin.therapeutic effect caused by the action of acetic acid regardless of ointment bases. Applied filler softens the impact of acid and provides the prolongation of the action of the active substance.Analysis of the known ointments used for diseases of hyperkeratosis.Example 1. The composition, includingGlacial acetic acid 10 30
Paraffin 19 30
Lanolin anhydrous Rest to 100
Options specific to the implementation of the ointment of example 1 is shown in the table.The ratio of the components is chosen experimentally and provides a high therapeutic effect.Indications for use proposed ointment: hyperkeratosis treatment of various localization, mainly the heel, stop. Also effective for the treatment of corns (Tiloma), but this requires a more long term treatment.Example 2. Preparation of ointment.The ointment contains glacial acetic acid and M90 70. First prepare the ointment basis of a mixture of anhydrous lanolin and paraffin health, taking as 100 the composition of the mixture and its components, wt. lanolin 60 65; paraffin else. The procedure for preparation of the following: 1) melted in a water bath a mixture of components ointment bases at 85 100oC while stirring with a glass rod until a homogeneous melt; 2) in the melt add under the thrust of glacial acetic acid in the ratio given in the formula, with stirring until a homogeneous mixture; 3) the mixture is sealed and cooled to room temperature with shaking, until you have a uniformly thickened ointment, which is the final product of the ointment with antihyperuricemic activity. Spend all technological processes, as well as storage and packaging in glass or other acid-proof container.Treatment method.The ointment is applied in a thin layer on the intact (no cracks and wounds) skin of the feet, heels and other parts of the body where there are hyperkeratosis treatment. Apply at any time of the day on the skin, without preliminary preparation. Treatment: usually, it only takes 3 to 5 treatments; treatment of corns requires a longer time: 3 to 4 months, in more severe Suspiria was carried out on volunteers 50 women and men ranging in age from 24 to 52 years, previously treated (without success) protivopozharnoi ointment.The results of the experiment are presented in the table.As follows from the table, the best results are obtained by application of ointment with a maximum content of acetic acid, however, the ointment with the content of 10 hours of acetic acid operates more smoothly and can be used on more sensitive areas of the skin, and not just heels and feet. According to the observations ointment effective and hyperkeratosis treatment in the presence of skin defects (cracks, erosion), while the patient experiences intermittent burning sensation. Ointment with antihyperuricemic activity, including the current tool and the underlying, characterized in that as the current tools it contains glacial acetic acid in a ratio of components, wt.Glacial acetic acid 10 30
Paraffin medical 19 30
Lanolin anhydrous Ostalnoe
FIELD: medicine, narcology.
SUBSTANCE: one should detect satisfaction insufficiency syndrome due to performing genetic analysis by the presence of, at least, one of the genes coding the exchange of neuromediators being the constituents of human satisfaction system. One should compensate satisfaction insufficiency due to performing, at least, one complex of physical exercises. Moreover, in case of availability of pathological gene allele of dopamine D2 receptor and/or protein gene of reverse dopamine capture in patient one should apply the complex of physical exercises including those to provide sedative effect, and in case of availability of pathological gene allele of dopamine-beta-hydroxylase protein one should apply the complex of physical exercises including those that induce an activating effect. In case of availability of pathological gene allele of dopamine D2 receptor and/or protein gene of reverse dopamine capture one should apply additional food biologically active additives based upon amino acids being the precursors of neuromediators, such as taurine, D-, L-phenylalanine in combination with 5-hydroxytryptophan, hypericin and vitamin B6, and in case of pathological gene allele of dopamine-beta-hydroxylase protein one should additionally apply food biologically active additives based upon amino acids being the precursors of neuromediators, such as: taurine, tyrosine and/or dimethylaminoethanol, lecithin and group B-vitamins. The present innovation enables to take into account pathological disease mechanism.
EFFECT: higher efficiency of prophylaxis.
14 cl, 5 ex