The method of obtaining 2-naphthol
(57) Abstract:The method of obtaining 2-naphthol by sulfonation of naphthalene with sulfuric acid at 160-163oWith, hydrolysis, Stripping acute water vapor and neutralizing the resulting sulfatase, alkaline melting the obtained reaction mixture, processing the obtained melt water, acidification received naphthalate sodium and selection of the target product, characterized in that before Stripping sulfones mixed with a hydrocarbon selected from the group of benzene, toluene, xylene or naphthalene, at 60o-90oAnd water taken in the ratio 1 : (0,25-1,0) : (0,4-1,2).
SUBSTANCE: present invention relates to a method for synthesis of 1,3,5-trihydroxybenzene (phloroglucinol) used as an initial component for synthesis of epoxide and thermosetting resins for making protective coatings, as a semi-finished product in making dyes etc. The method involves hydrolysis of a 1,3,5-triaminobenzene salt with an inorganic acid while heating in an acidic medium. The hydrolysis process is carried out in suspension with mass ratio salt: water equal to 1:1.75 in the presence of an ammonium salt. As a rule, the 1,3,5-triaminobenzene salt with an inorganic acid used is a dihydrate of 1,3,5-triaminobenzene disulphate or a dehydrate of 1,3,5-triaminobenzene diphosphate.
EFFECT: method increases efficiency of the process and enables to obtain a highly pure product.
2 cl, 3 ex
SUBSTANCE: invention relates to a method of producing 2-(4-hydroxyphenyl)ethanol (p-thyrozol), having a marked stimulating effect, immunomodulating and cardioprotective activity, anticarcinogenic and anti-inflammatory properties. The method includes nitrating 2-phenylethanol, reducing 2-(4-nitrophehyl)nitroethanol and nitrating 2-(4-aminophenyl)ethanol with subsequent hydrolysis of the diazo-compound. Synthesis and hydrolysis of the diazo-compound is carried out in the presence of n-toluene sulphonic acid with molar ratio 2-(4-aminophenyl)ethanol:n-toluene sulphonic acid = 1.0:2.1-3.0.
EFFECT: method enables to obtain an end product of high quality from affordable material without using hard-to-get and expensive reagents, as well as hazardous production processes.
2 tbl, 15 ex
FIELD: chemical industry; methods of production of the phenols by the catalytic decomposition of the cumene hydroperoxide into phenol and acetone.
SUBSTANCE: the invention is pertaining to production of phenols by the catalytic decomposition of the cumene hydroperoxide into phenol and acetone. The method provides for oxidization of the cumene into the cumene hydroperoxide, catalyzed by the acid decomposition of the cumene hydroperoxide, neutralization of the produced product of the decomposition, maintaining the product in the homogeneous phase before neutralization, which is conducted by means of the aqueous base. The phenol is separated by fractionation of the neutralized product. The aqueous base represents the water solution of the sodium hydroxide or phenoxide. In particular use the regenerated phenoxide, at least, on one phase of the treatment at production of the phenol. It is preferential to add the sodium hydroxide water solution to the reaction product in such a concentration and such amount, that to receive the concentration of sodium phenolate in the homogeneous phase from 0.2 up to 2.5 mass %. The temperature of the homogeneous phase after the add-on of the aqueous base is set within the range of 20°С-150°С, the preferable temperature is within the range of 60°С-120°С. It is preferential, that the reaction product is saturated with the oxygen-containing gas. The technical result of the invention is the decreased quantity of the undesirable impurities in the products of the acid decomposition of the cumene hydroperoxide.
EFFECT: the invention ensures the decreased quantity of the undesirable impurities in the products of the acid decomposition of the cumene hydroperoxide.
13 cl, 4 ex
SUBSTANCE: invention relates to chemistry of organic compounds and a method of concentrating resorcinol from aqueous solutions, involving extraction-sorption concentration of resorcinol using a sorbent in form of elastic foamed polyurethane modified with a solution of tributylphosphate in hexane in volume ratio of tributylphophate: hexane equal to 1:(0.5-1) and weight ratio of elastic foamed polyurethane: tributylphosphate equal to 1:(0.5-0.75).
EFFECT: high coefficient of extraction-sorption concentration, increase in degree of extraction to 98,6% and low consumption of tributylphosphate.
1 tbl, 3 ex
SUBSTANCE: method of producing phenol involves: a) oxidising cumene to obtain an oxidation product containing cumene hydroperoxide; b) splitting said oxidation product using an acid catalyst to obtain a splitting product containing phenol, acetone, hydroxyacetone and impurities; c) neutralising and washing said splitting product with an alkaline aqueous medium to form a neutralised splitting product; d) separating said neutralised splitting product via at least one distillation step to obtain at least a fraction containing phenol, and an aqueous fraction containing hydroxyacetone; e) treating said aqueous fraction with an oxidative reagent in the presence of a base to obtain an alkaline aqueous medium with low content of hydroxyacetone; f) recirculating at least a portion of said aqueous alkaline medium to the neutralisation and washing step (c) and g) extracting phenol from said phenol-containing fraction obtained at step d).
EFFECT: obtaining the desired product with efficient removal of the by-product - hydroxyacetone.
25 cl, 1 dwg, 2 ex
SUBSTANCE: invention relates to a method of concentrating pyrogallol from aqueous solutions, which can be recommended for analytical inspection of sewage coming in for biological treatment. The dislcosed method involves concentration of pyrogallol from aqueous solutions acidified to pH=1-5 at temperature of 20±2°C using an organic solvent of tributyl phosphate, said tributyl phosphate modifying crushed rigid polyurethane foam in weight ratio of polyurethane foam to tributyl phosphate equal to 1:(2.0-2.6).
EFFECT: method increases the concentration factor of pyrogallol and reduces consumption of organic solvent.
2 ex, 1 tbl
SUBSTANCE: method comprises: (1) a step of forming bisphenol A by condensing phenol and acetone in a reactor filled with a catalyst based on a strongly acidic cation exchange resin partially modified with a sulfur-containing amino compound, thereby producing a reaction mixture containing bisphenol A (2) a step of isolating a component with low boiling points from the reaction mixture produced in step (1), thereby producing a crystallization material containing concentrated bisphenol A, (3) a step of cooling the solidification material produced in step (2), with the crystallization of this adduct of bisphenol A and phenol to produce the crystals of adduct of bisphenol A and phenol, and to select the crystals from the reaction mixture, (4) a step of removing phenol from the adduct crystals of bisphenol A and phenol produced in step (3) to produce bisphenol A. The process also includes: (R1) a step of separating water and phenol from the phenol-containing effluent that is formed in the bisphenol A production step using methyl isobutyl ketone, followed by extraction of crude phenol, and (R2) a step of distilling and purifying crude phenol, extracted in step (R1), to produce phenol with a sulfur content of at most 0.5 ppm wt and a nitrogen content of at most 0.1 ppm wt, and phenol produced in step (R2) is re-used in, at least, one of steps (1) to (4).
EFFECT: method allows to produce bisphenol A of high quality.
10 cl, 4 ex
SUBSTANCE: invention refers to a method for the one-stage production of (3-hydroxypropyl)naphthols of having a structure of R1=CH2CH2CH2OH, R2=OH, R3=H; R1=OH, R2=CH2CH2CH2OH, R3=H; R1=OH, R2=CH2CH2CH2OH, R3=CH2CH2CH2OH; R1=OH, R2=T-Bu, R3=CH2CH2CH2OH, effective biologically active substances of neutropic action. The method consists in conducting a reaction of α-, β-naphthols, their derivatives or their sodium salts with allyl alcohol and alkali at temperature 100-170°C. A purified product yield is 40-60%.
EFFECT: higher yield.
SUBSTANCE: application relates to a marking label for gasolines which represents hydroxyl-containing derivatives of aromatic series, wherein the hydroxyl group is connected directly to the aromatic ring, selected from a series of resorcinol, 4-hexylresorcinol or β-naphthol. The proposed label can be used in low concentrations.
EFFECT: absence of its influence on the performance characteristics of marked gasolines.
3 dwg, 4 ex