Method p. i. fedorischeva obtain drugs having wound healing properties
(57) Abstract:The essence of the invention: prepare a mixture of copper acetate (1 wt.h.), sodium hydrogen carbonate (from 0.4 to 0.8 wt.h.) and talc (from 0.01 to 0.05 wt. h ), hydratious her, dried and crushed to powder. The resulting product is used in the form of lotions for the treatment of burns, frostbite, erysipelatous inflammations. table 1. The invention relates to medicine, namely to methods for drugs.A method of obtaining a medicinal product by mixing formalin, glycerin, ascorbic acid and distilled water /1/.This method is quite simple to implement, but its scope is limited to profilaktika suppuration around the spokes.The prototype of the proposed technical solution is the method of obtaining effective drug, developed by P. I. Fedorishin /2/. The method consists in preparing a mixture of 5 wt.h. copper acetate
Cu(CH3COO)2H2O and 3 wt.h. sodium bicarbonate - NaHCO3after hydrating with water at a ratio of 1:1 by weight. Upon completion of the hydration of a dried mixture of a CR in the treatment of burns, frostbite, erysipelatous inflammations. However, the method of obtaining the drug of ethnological, as the necessary conditions for its exercise are: fixed value of the ratio of water and a mixture of hydration (1:1 by weight); limit temperature drying (not more than 35oC).In addition, the lotion prepared on the basis of the drug retains its effectiveness is not more than eight days if stored in a dark place at room temperature.The aim of the invention is to improve the workability and effectiveness of the method.The objective is achieved by the proposed method comprising preparing a mixture of 1 wt. including copper acetate, 0.4 to 0.8 wt.h. of sodium bicarbonate and from 0.01 to 0.05 wt.h. talc. The resulting mixture hydratious water at a ratio of components, M, is equal to from 1.0 to 1.5 wt.h. water 1.0 wt.h. of the mixture. Upon completion of the hydration wet mass is dried at a temperature T.Improving the processability of the method is achieved by expanding the range of variation of the mass ratio of the mixture and water when hydrating and removing restrictions on the temperature of drying, increasing efficiency by extending the storage is and the mixture additionally contains talc, representing the magnesium silicate approximately the following composition 4SiO23MgOH2O. This is a very soft white or slightly grayish powder without smell and taste. In medicine is used for powders and as indifferent filler for cooking pastes and tablets.The adaptability of the method was evaluated by comparing the duration of the drying drug LW, hThe effectiveness of the method was assessed by the ability of lotions, prepared on the basis of a medicinal product, to restore the homogeneity after a certain length of storage. To do this, prepare a lotion from 0.25 g drug and 500 g of distilled water and kept it in a dark place during the time of HHS day. During storage lotion exfoliates, i.e., forms a transparent portion and sediment. A lotion which was for 5 min, poured into a graduated cylinder and left to rest for 10 minutes Then determined the volume of the clarified part lotions 0, less Than 0, the higher the homogeneity (uniformity) of lotion.An example of the method. The addition of copper acetate with a weight of 100 g was mixed with 60 g of sodium bicarbonate and 3 g of talc. The resulting mixture was mixed with 163 g Aadnoy the consistency of the mass. Then propertybase the mixture was dried at a temperature of T=60oand grind to powder.The results of the study drug, prepared in accordance with the foregoing example, when different modes of implementation of the method is given in the table.The table shows that when carrying out the known method (experiment 1), the duration of drying is 12 h, the volume of the clarified part lotions after 8 days of storage 10 and after 16 days 45 (experiment 7). When the temperature drying to 60o(experiment 8), the duration of drying is reduced to 8 h, however, the properties of the lotions, the estimated volume of the clarified layer deteriorate.For the proposed method (experiments 2, 3, 4, 5, 6) the reduction in the duration of the drying occurs while restoring the original properties of a lotion after storage. Thus, this goal is achieved only when declared essential features.The resulting implementation of the way the drug is used in the form of lotions for the treatment of burns, erysipelatous inflammations, frostbite.The analysis of the proposed technical solutions pokazyvaet specialist is not obvious from the prior art. This method is industrially applicable, as confirmed by the examples of its implementation. Thus, the proposed technical solution meets all the required criteria for the recognition of his invention. The method of obtaining drugs having wound healing properties, including the preparation of a mixture of copper acetate and sodium bicarbonate, with subsequent hydrating, drying and grinding, characterized in that in the preparation of the mixture into it further added talc, 1 wt.h. copper acetate take 0,4 0,8 wt.h. of sodium bicarbonate and 0.01 to 0.05 wt.h. talc.
FIELD: pharmaceutical engineering; medical engineering.
SUBSTANCE: method involves carrying out nuclear magnetic resonance tomography of human or animal blood circulation system containing chelating ion complexes of bivalent and valence three paramagnetic metals of (I)X-L-Y formula, where X is the polyamide carbonyl ligand residue and Y is the gallic acid derivative, .
EFFECT: high accuracy of diagnosis.
FIELD: veterinary science.
SUBSTANCE: invention relates to a composition used in prophylaxis and treatment of anemia in agricultural animals and poultry that comprises a mixture of chelates of iron, copper, zinc, cobalt, sodium, calcium with ethylenediamine-N,N'-disuccinic acid in the following ratio of components, wt.-%: copper chelates with ethylenediamine-N,N'-disuccinic acid, 0.45-0.60; zinc chelates with ethylenediamine-N,N'-disuccinic acid, 1.40-1.45; cobalt chelates with ethylenediamine-N,N'-disuccinic acid, 0.075-0.08; sodium chelates with ethylenediamine-N,N'-disuccinic acid 42.0-44.0; calcium chelates with ethylenediamine-N,N'-disuccinic acid, 12.0-13.0, and iron chelates with ethylenediamine-N,N'-disuccinic acid, the balance. Agent provides enhancing the blood hemoglobin content in animals by 28% as compared with animals receiving neither anti-anemic agents and by 12% as compared with animals receiving the preparation-analog.
EFFECT: enhanced effectiveness of composition.
4 tbl, 4 ex
FIELD: chemical-and-pharmaceutical industry, in particular agents for ecological medicine.
SUBSTANCE: claimed agent contains medical plants, plant extracts, and natural antioxidants and comprises three complexes, wherein the first one includes medical plants which simulate all systems of excretory clearance and increase detoxification activity of immune cells; the second one includes plant components which stimulate I and II phase biotransformation enzyme activities, i.e. intracellular clearance processes; and the third one includes plant extracts and antioxidant complex which protect cell from toxic action of free radicals. Method for endoecological correction by administration of complex agent based on plant raw materials, vitamins and microelements also is disclosed.
EFFECT: new complex agent to activate function of natural human body clearance systems, to stimulate main mechanisms of body clearance such as excretory intracellucar medium clearance, xenobiotic intracellular transformation and antioxidant protection.
2 cl, 2 ex, 6 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention concerns medicine, particularly medicines for a wide range of diseases caused by immune deficiency, intestine and rectum mucosa and biliary tract inflammation, reduced organism resistance. 40-70% aqueous alcohol solution based on common St. John's wort, common plantain, stinging nettle, calendula and costmary at quantitative ratio of 30:30:20:10:10 , respectively is used as immune modifying medium, with addition of 1.32 g % of five water soluble sulfates of zinc, copper, iron, cobalt and molybdenum at ratio of 1.0: 0.3: 0.02: 0.002: 0.002 respectively. New galenic medicine facilitates non-specific organism resistance (survival rate) enhancement.
EFFECT: medicine with antiallergic effect, positive effect on cell immunity factor, on T-helper and T-suppressor unit ratio (CD 4/CD 8, %), reliable reduction of originally high passive factors for patients with non-specific ulcerative colitis.
6 ex, 1 tbl