The simulation method asystole ventricular

 

(57) Abstract:

Usage: medicine, experimental cardiology. Essence: on the chest anesthetized dogs on the heart area impose two electrodes and cause monopolar defibrillation discharge amperage 13-36 A. the Method allows to increase the duration of the period of asystole ventricular 8-10 times.

The invention relates to medicine, namely to cardiology and can be used to search for new cardioprotective substances.

It is known that asystole ventricular heart is one of the most frequent causes of sudden death, often causes the syndrome, Morgagni-Adams-Stokes equations. It is obvious that the development of adequate methods of treatment and prevention of sudden death due to asistoliei ventricular impossible without the creation of effective models of this form of heart disease.

There is a method of modeling asystole ventricular heart by electrical stimulation of the ventricles of the heart with a frequency far exceeding their own heart rate followed by a sudden cessation of electrical stimulation of the heart (E. B. Babsky, HP Ulyanisky. Electrical wiring in the ical solution. The known method is not free from some drawbacks, in particular, requires opening the chest for implantation of electrodes or sensing cavities of the heart in order intracardially implantation of electrodes, and a non-permanent value of the length of the period arising asystole of the heart ventricles, which greatly depends on the duration of the period of stimulation, the degree of functioning of the atrioventricular node, i.e., characterized by a rather low reproducibility.

The purpose of the invention improve the reproducibility.

This goal is achieved as follows. Anesthetized animal, such as dog, weighing 4-8 kg is put on artificial respiration, shaved chest of the animal strengthened standard from the electrodes of the defibrillator 8 cm with 4-ply gauze napkins, liberally soaked in hypertonic sodium chloride solution and heart to apply monopolar defibrillation pulse type Edmark amplitude 1500-1900 volts (current 13-36), value given energy 55-185 j. When this occurs asystole ventricular duration 40-65 C. In control experiments with the impact on the heart of obychnoystali at the indicated values of the stimulus was not more than 6-20 C.

Example 1. The dog is a male, weight 5,5 kg, under General anesthesia and artificial respiration on the heart area of the superimposed two-disk electrode with a diameter of 8 cm Marked monopolar defibrillation pulse amplitude 1180 volts (7,8 And, given the energy of 35 j). Appeared asystole ventricular duration of 2.8 C. maintaining sinus rhythm 120 beats/min.

Example 2. The dog is a male, weight 5,5 kg heart caused monopolar defibrillation pulse amplitude 1520 volt (13 amp, value given energy 56 j). Appeared asystole ventricular duration of 39, after which he restored a normal heart rhythm.

Example 3. The dog is a male, weighing 6.5 kg heart caused monopolar defibrillation pulse amplitude 1850 volts (25 a given energy 155 j). Appeared asystole ventricular duration 26 sec, and then recovered to a normal heart rhythm.

Example 4. The dog is a male, weighing 6.5 kg heart caused monopolar defibrillation pulse amplitude 1680 volts (36 And, given the energy of 184 j). Appeared asystole ventricular duration of 65 seconds, and then within 20 registered atrioventricular blockade of the II degree.

Example 5. The dog is a male, weighing Leah ventricular length: 6, then he restored a normal heart rhythm.

Thus, the experiments (19 dogs) showed that the most optimal option for modeling long asystole ventricular heart is monopolar defibrillation pulse amplitude 13-36 (the voltage 1500-1900 volts). This range is noted for quite a long period of asystole ventricular without damage defibrillation discharge.

The simulation method asystole ventricular heart by electrical stimulation of the heart, wherein the heart irritate monopolar section defibrillator amperage 13 36 A.

 

Same patents:

The invention relates to medical equipment, namely to devices for simulating blood supply to tissues

The invention relates to the field of medicine
The invention relates to medicine, namely to the experimental traumatology orthopedics
The invention relates to medicine, namely to experimental surgery and can be used for modeling diastasis of recti
The invention relates to medicine, namely to experimental medicine

especially dangerous infections in ophthalmology
The invention relates to experimental physiology, medicine
The invention relates to medicine, namely to experimental neurology
The invention relates to medicine, namely immunology

The invention relates to experimental medicine and is intended for receiving a model grammaticalhistorical septic process

Defibrillator // 2049494

FIELD: medicine.

SUBSTANCE: method involves creating therapeutic circuit fixed on patient body, at least two working therapeutic electrodes, measuring and analyzing patient-dependent electrophysical parameters, charging capacitive storage and its later discharging to the working therapeutic electrodes controlled with control unit. Transmitting defibrillation impulse of given power in discharging is carried out in dosed manner first with the first portion W1 of given power dose with the second portion W2 being accumulated on inductive defibrillation power accumulator and then with the second portion W2 of given power dose. Ratio of the first portion W1 of given power dose to the second portion W2 of given power dose of defibrillation impulse is selected from the range of 0.01 to 150. Defibrillation impulse current intensity is selected only when emitting the first portion W1 of given power dose. Cardiodefibrillation impulse is built as bipolar Gurvich impulse. The given power quantity usable for charging the capacitive defibrillator storage is selected to be equal to a value from the range of 4-500 J, defibrillation impulse current intensity being selected from the range of 0.005 to 175 A and voltage equal to a value from 3 to 30000 V. Means has power supply source having unit for controlling charge level of the capacitive storage, unit for building defibrillation pulses, switchboards formed by controlled keys, at least two working therapeutic electrodes and diodes bypassing the controlled keys, resistive current transducer, analog-to-digital converter and control unit having required functional communications to the analog-to-digital converter and controlled keys. The resistive current transducer is in current feeding bus having minimum potential relative to measuring unit under operation having analog-to-digital converter in its structure.

EFFECT: enhanced effectiveness of usage; high safety of patient treatment procedure.

7 cl, 9 dwg

FIELD: medical engineering.

SUBSTANCE: device has means for producing defibrillation pulse having electric current source, capacitive electric energy storage, high voltage commutator, control unit and control system having patient electrophysical parameter control means and high voltage pulses control means and at least two therapeutic electrodes. The device also has means for compressing human body chest manufactured for instance as elastic cuff having a built-in ultrasonic radiator.

EFFECT: high reliability in delivering defibrillation pulse at given address.

5 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: invention concerns medicine area, namely to area of urgent cardiological resuscitation. The heart defibrillator for treatment of the patient in case of cardiovascular activity termination by means of the shock blow provided with the dosed out diphasic electric discharge of high-voltage condenser through the H-shaped bridge circuitry, contains the high voltage commutator A, B, C or D in each of the branches. According to the invention each of opposite polarity phases of a diphasic shock blow is managed in two stages on time in such a manner that for each pair of the commutators concerning the given phase, the first of pair commutators is changed over in leading state and remains leading during all this phase whereas the second commutator of this pair is shorted with some time delay in relation to the first commutator throughout some operated duration for establishment of a current flow through a body of the patient during this phase, and the second phase is processed in the same way by means of other pair of commutators.

EFFECT: wide use of the defibrillation device.

13 cl, 6 dwg

FIELD: physics.

SUBSTANCE: invention can be used for generating powerful bipolar and multiphase electric pulses. The method involves controlling series-connected single-type power cells containing electrical energy accumulators, and providing switching of positive and negative polarity of the connection of the energy accumulator to leads of the cell, and switching the electrical energy accumulator to leads of the cell, and having bypass diodes which provide flow of current through leads of the cell when electrical energy accumulators are disconnected from the leads of the cell. A signal from a current sensor is transmitted to the analogue input of a digital signal processor (DSP), from the digital outputs of which the power cells are controlled. Before completion of generation of a pulse, the digital signal processor periodically converts the signal from the current sensor, standardises it, calculates deviation from the current value stores in the digital signal processor of the pulse form and compares the deviation with four limiting values. Signals for controlling power cells are output from the outputs of the digital signal processor depending on the comparison results.

EFFECT: simplification of the method of generating pulses and reducing the number of circuit components.

7 dwg, 1 tbl

FIELD: medicine.

SUBSTANCE: group of inventions refers to medical engineering and is designed to restore normal rhythm and contractile function of heart. Automatic external defibrillator includes a pair of electrode plates; a controller connected to the electrode plates through the front-end circuit of ECG and running for analysis of ECG signals to determine whether ECT is recommended, high-voltage circuit connected to the electrode plates for carrying out biphasic defibrillation electric shock when ECT/treatment protocol storage device is recommended, which retains one or more of treatment protocols that include the protocol of single electroshock controlled by AED for carrying out a single biphasic electric defibrillation, followed by a period of cardio-pulmonary resuscitation (CPR); while the controller is connected to the treatment protocol storage device working to implement the protocol of single electric shock where the single electric shock protocol is the default protocol for AED. The second version of defibrillator also contains a battery connected to AED power circuit; user interface control elements the administrator works with to select either a single electric shock protocol, or protocol of repeated electric shocks through the resident piece of software in AED, without removal of battery or linking-up external hardware or software to the AED.

EFFECT: providing opportunities of time management of cardio-pulmonary resuscitation.

14 cl, 10 dwg

FIELD: electricity.

SUBSTANCE: bipolar signal shaping device includes electric energy accumulator, controlled electronic switches switching it and control diagram of the above switches. For shaping of positive and negative polarity signal the electric energy accumulator which is connected to circuit of in-series connected switches is installed. Each of switches is parallel connected to resistor. Control circuit of switches for changing the pulse shape controls the activation of electronic switches and circuit for shaping of bipolar signal. Bipolar signal shaping circuit consists of four switches in-series connected to electric energy accumulator and pulse shape change circuit so that when the first and the fourth switches close, current flows through load in the direction shaping positive polarity signal and when the second and the third switches close, current flows through load in the direction shaping negative polarity signal. Control signals of electronic switches are supplied from control diagram for shaping of bipolar signal.

EFFECT: simplifying and optimising electric circuit.

3 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, namely to apparatuses for emergency medical care. The apparatus comprises a piece of clothing, a control unit arranged thereon used to control at least one physiological function of the patient to state an emergency, and a therapeutic device arranged on the piece of clothing and operatively connected to the control unit for treating the patient. The therapeutic device is a respiratory therapeutic device applied to supply oxygen, an oxygen-containing gas mixture and/or at least one drug endotracheally, and comprises a perforating unit to perforate the patient's trachea below the larynx.

EFFECT: use of the invention provides extending the range of apparatuses for emergency medical care.

20 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment, namely to system for carrying out CPR. Device of providing feedback in carrying out CPR contains sensor of compression, adapted for placement between rescuer's hands and victim's chest, module of control with feedback, connected with compression sensor, and programmed for registration of output data of compression, their analysis, identification of single compression cycles and comparison of single cycles of compression with multitude of evaluation criterions. Matrix of comparison is output on presentation device, and each element of matrix corresponds to comparison of one of single compression cycles with one of multitude of evaluation criteria. Method of feedback presentation includes stages of carrying out compression of victim's chest through sensor of compression, registration, analysis, identification and comparison of output data from compression sensor with multitude of evaluation in form of comparison matrix elements.

EFFECT: invention makes it possible to increase efficiency of improvement of technical methods in carrying out CPR.

19 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment, in particular, to systems of ECG monitoring, which trace indications of ciliary arrhythmia (CA) in real time. System of ciliary arrhythmia monitoring contains source of electrocardiogram data, extractor of P-wave signs, extractor of interval R-R signs, CA classifier, reacting to P-wave sign and interval R-R sign, which classifies cardiac rhythm as that with CA or without CA, display, reacting to CA classifier for displaying CA classification, and user's input for regulation of balance sensitivity/specificity of identification of rhythm with CA, with user's input additionally containing selection of type of patient population for automatic adjustment of nominal working parameters of identification of rhythm with CA for selected type of patient population.

EFFECT: invention will make it possible to simplify adjustment of nominal working parameters Of CA monitoring system for selected type of patient population.

14 cl, 11 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment. An external defibrillator for two-phase defibrillation waveform supply comprises a high-voltage circuit, which accommodates a condenser, as well as a pair of electrodes and a number of switches. The high-voltage circuit is presented to charge the condenser to supply the defibrillation pulse. The switches comprise an H-bridge, connected between the condenser and electrodes and can be connected to first and second phases of the two-phase defibrillation waveform to the electrodes. A second-phase tilt is adjustable. The controlled conduction path comprises the H-bridge switch and enables the controlled conduction path for the second phase of the two-phase waveform.

EFFECT: using the invention enables higher safety and effectiveness of defibrillation.

12 cl, 6 dwg

Up!