The method of treatment and/or prevention of rectitem

 

(57) Abstract:

The invention relates to medicine. The method of prevention and/or treatment of radiation rectitis includes the introduction into the rectum of medicines containing copper derivative of chlorophyll and anesthetic. The method differs in that it is obtained from the seaweed laminaria copper derivative of chlorophyll diluted in a ratio of 1:(5 - 10) in a 0.25% solution of novocaine and injected into microclysters rectum 2 times a day for 20 to 40 ml, then the patient is kept in the supine position consistently on the back, chest, right and left side for 10 to 15 minutes in each position.

The invention relates to medicine, namely to methods for the prevention and/or treatment of radiation rectitis using insertion into the rectum of herbal medicines.

Known way to prevent radial ranjita encountered a significant portion of patients after radiation therapy for cervical cancer, including the introduction into the rectum 10 ml 5-10% solution of dimethyl sulfoxide, and application of metronidazole dissolved in dimethyl sulfoxide. However, this does not preclude later erosive and ulcerative radiation reckit the tx2">

There is a method of radiation treatment of erosive and ulcerative rectitem, including anti-inflammatory drugs, and the use of a 5% solution of dimethyl sulfoxide in microclysters 50-70 ml in the morning and in the evening for 12-15 days. As subacute inflammatory process additionally apply therapeutic enema with complex emulsion "sinason", jelly solkoserila and vitamin oils (fish oil, cartoon, rosehip and sea buckthorn). The disadvantage of this method is the lack of used drugs, their high cost.

A prototype of the proposed method for the prevention and/or treatment of radiation rectitis is a method of treatment of rectal diseases, such as hemorrhoids, ulcers, fissures, fistulas, etc. which in the rectum injected a drug in the form of suppositories, ointments, aerosols containing copper derivative of chlorophyll. The main disadvantage of the prototype is that the song was not used in radiation renjith, which have a different origin (caused by exposure to radiant energy) than the banal rectify (called microbial flora). Radiant energy in contrast to the microbial flora affects not tricotage adrectal fiber. Therefore, when radiation and banal renjith therapeutic tactics must be different.

The disadvantage of the prototype is the need to produce a dosage form suitable for introduction into the rectum and includes some scarce components.

To expand the Arsenal of drugs for the treatment and prevention of radiation rectitis, using copper derivative of chlorophyll, produced by industry for various purposes, it is proposed a method for the prevention and treatment of radiation rectitis, including the introduction into the rectum of medicines containing copper derivative of chlorophyll, derived from seaweed kelp (seaweed) was diluted in a ratio of 1:(5-15) in a 0.25% solution of novocaine and injected into the micro directly into the rectum 2 times a day for 20-40 ml of the obtained solution, and after the introduction maintain the patient in the supine position consistently on the back, the abdomen, the right and left side for 10-15 minutes in each position.

Declare a set of distinctive features, without organizing the production of special dosage forms to be used for the prevention and treatment of radiation rectitis produced promyshlennost on the intended method is as follows. Manufactured by industry from the seaweed laminaria (seaweed) copper derivative of chlorophyll in the ratio 1: (5-10) is dissolved in a 0.25% solution of novocaine and injected into microclysters rectum 2 times a day for 20-40 ml, and after the introduction maintain the patient in the supine position consistently on the back, chest, right and left side for 10-15 minutes in each position.

P R I m e R 1. Patient P. 35 years. In 1989 he took a course sachitano-radiation therapy (intracavitary and external beam radiation) about cervical cancer stage RO. Asked again at Oncology research Institute 26.11.90, with complaints of pain in the rectum and pryamokishechnye bleeding. If rektoromanoskopii revealed erosive or ulcerative late radiation recta. For treatment received microclysters with sea buckthorn, rosehip, solutions metalla with novocaine, alcohol-novocaine-hydrocortisone blockade. The effect is not there. In February 1991, the course of treatment by the present method. The patient daily during the month 2 times a day was administered into the rectum diluted in the ratio 1:10 in a 0.25% solution of novocaine copper derivative of chlorophyll in the amount of 30-35 ml one month after treatment in the control of rektoromanoskopii mucous got. In 1990, he took a course sachitano-radiation therapy for cancer of the cervix RO. Since February 1991, profuse rectal bleeding. Severe anemia. If rektoromanoskopii and fibrocolonoscopia erosive or ulcerative recta. Attempt treatment on an outpatient basis with micro sea buckthorn, rosehip, solutions metalla with novocaine, Dimexidum and alcohol-novocaine-hydrocortisone blockade was not successful. In January-February 1992 the patient, the course microenemas solution of copper derivative of chlorophyll in stationary conditions. The patient daily twice a day was administered into the rectum diluted in the ratio 1:5 in a 0.25% solution of novocaine copper derivative of chlorophyll in 20 ml of only 45 procedures. At discharge remained only edema of the mucosa of the anterior wall of the rectum when rektoromanoskopii.

P R I m e R 3. Patient P. 63. In 1991 he took a course sachitano-radiation therapy for cancer of the cervix stage 3. In December 1991, he enrolled in horoscope.cancer with suspected colorectal cancer. Upon receipt worried about the pain in the rectum and rectal bleeding. In the examination diagnosed with radiation ulcer of the rectum. The treatment of various drugs, p is the breaking of chlorophyll with novocaine. At discharge scarring, complete epithelialization of the ulcer of the rectum.

Late radiation rectify were treated in this way in 16 patients. All after treatment stopped rectal bleeding, disappeared or significantly decreased pain in the rectum, when the control rektoromanoskopii was determined by the reduction of swelling and hyperemia mucous membrane of the rectum, expressed epithelialization damaged areas.

As prophylaxis of radiation rectitis treatment were 15 people. In the result it was found that in the process of radiation therapy there is no need to take breaks between courses of irradiation, because the characteristics of local radiotherapy complications or completely absent or expressed so insignificant that allows you to continue a course of radiation therapy without interruption. Upon completion of the course of radiation therapy does not require treatment with local radiotherapy complications. Within 4 months of observations, none of these patients also were observed late radiation rectify.

The METHOD of TREATMENT AND/OR PREVENTION of RECTITEM, including the introduction into the rectum of medicines containing copper derivative of chlorophyll and anesthetic, characterized in that the treatment radiation rectitude novocaine and injected into microclysters rectum 2 times a day for 20 to 40 ml of the resulting solution, then the patient is kept in the supine position consistently on the back, chest, right and left side for 10 to 15 minutes in each position.

 

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