The method of applying aseptic protective coatings and device for its implementation

 

(57) Abstract:

Usage: in medicine, in particular for the application of bandages, plasters and coatings permeable to gas but impervious to microorganisms and dust. The essence of the invention: method of applying aseptic protective coating on the skin is that the solution containing 1 to 50 wt. % of fibre-forming polymer, aseptic drug and the solvent serves to protect the skin in the form of at least one jet. The coating formed in the electrostatic field of 1 to 5 kV/see This method is carried out using a device containing a tank filled with a solution, the microcompressor connected with the cavity of the container through the tube not reaching the level of solution in the tank, pressure cap installed on it forming a head with a capillary tube, one end of which is connected to the siphon tube, passed through the cover into the vessel and the other end is made free and taken out of the forming head. The device is provided with a source of high electrical voltage, one pole of which is connected to the capillary, and the other grounded. In the device cavity forming head may be the connection is and is installed with a clearance relative to the wall of the forming head. 2 S. and 1 C.p. f-crystals, 2 Il.

The invention relates to medicine, and more precisely relates to a method of applying a protective aseptic coating and device for its implementation, which can be widely used for the application of bandages, plasters for medical establishments, veterinary hospitals and other industries that require coating is permeable to gas but impervious to microorganisms and dust.

A known method of applying aseptic, therapeutic and protective coatings on the outer integument and the damage to the body by bandaging, and adhesion of these coatings adhesive patch, or medical adhesive. However, this method is not applicable in case of increased soreness and easy traumatized damaged surfaces, for example in the case of severe burns, extensive abrasions and the like.

Widely used in medical practice, the method of coating by spraying solutions of film-forming substances containing drugs, such as from aerosol cans, of which the liquid is fed under the action created in the spray pressure of the gaseous environment.

However, when this method is writenow surface, that does not preclude the irritant solvent until it dries. In addition, we obtain in this way the coverage is continuous and interfere with the normal gas exchange surface to be protected, which in some cases is unacceptable. A tight fit of these coatings to protect the surface hinders their subsequent destruction in case of increased soreness to the protected surfaces.

Widespread technique has received a coating methods by air atomization of liquid material on a grounded product or surface in an electrostatic field, we then obtain highly dispersed aerosols transported in an electrostatic field, deposited on a grounded surface and form a continuous film coating. To obtain highly dispersed aerosols air flow serves under high pressure or liquid before atomization saturate any gas inert with respect to it [1]

In the devices performing such coating methods, in addition to the high voltage source connected to the electrode, the capacity for sprayable material and pressure source using the sophisticated design of the spray feed air stream [2]

However, such devices are bulky and require a powerful source for creating air flow, which effectively precludes their use in medical practice. In addition, the atomization of materials leads to the formation of a continuous film coating, which is inherent in the above-described disadvantages, which virtually eliminates the use of them as aseptic protective or therapeutic coating.

The present of the invention is to create such a method of applying a protective aseptic coating and the device for its implementation, which will provide atraumatic coating, and its specified moisture and gas permeability, which in turn will help to create favorable conditions for healing of damage on the outer surface.

The problem is solved in that in the method of applying aseptic protective coating by feeding on the protected surface of the mixture of solvent and aseptic drug as a mixture, use a solution of polymeric fibre-forming compositions containing the aseptic preparation of which is directly on the protected surface to form the coating layer microfiber or paroliciste 1-50 wt. moreover, the solution of polymer composition serves as at least one stream.

Microfiber or porous structure of the coating layer of the stream of solution polymer composition is formed in the electrostatic field strength from 1 to 5 kV/see

The problem is solved also by the fact that the device for applying aseptic protective coating containing a forming head placed in its hollow body by the capillary, mud tank, put on a grounded surface, the high voltage source, one pole of which is connected to the electrode for applying voltage to the applied solution, the microcompressor, reported hose capacity, according to the invention, the capacity installed on the main body of the forming head, tightly connected with him and has two nozzles, one of which is connected to the microcompressor, and the open end of the pipe connected to the capillary, placed in the vessel below the level of its solution. The tank is provided with an additional pipe, one end of which is placed in the body cavity of the forming head, and the other end is placed in the vessel above the level of its solution.

Thanks spoets on the healing of damaged surface. In addition, the supplied stream of polymeric fibre-forming composition under the action of the electrostatic field is extruded into a thin thread, the pressure which when laid on the damaged surface during formation of the layer is almost not felt, since during the movement of the thread from the capillary to the protected surface is drying yarn from the solvent and the protected surface reaches the fiber diameter of 0.1-10 μm, which provides atraumatic coating and creates a structure, impervious to dust and micro-organisms. While the coating structure can apply through his pores additional amount necessary medication.

The possibility of filing a polymeric fibre-forming composition in the form of a stream, pulling the thread, and not its atomization, allowed to exclude the formation of a continuous film and the need to use air flow supplied under pressure in the direction to the damaged surface, which in General can serve as a source of delivery to it of microorganisms and dust. In addition, eliminates the need to use air flow supplied under pressure, has greatly simplified the design of the device, the th head. As a result, the device for applying aseptic protective cover compact, convenient and reliable in operation.

In Fig. 1 shows schematically a General view of the proposed device for applying aseptic protective cover of Fig. option 2 implementation capacity of the installation.

The proposed method of applying a protective aseptic coating is that the protective coating formed from a solution of known polymeric compositions capable of fiberizing, for example, polystyrene of high molecular weight, perchlorovinyl, rizal and so forth, and containing aseptic, for example iodine, brilliant green, the drugs.

The polymeric fibre-forming composition is contained in solution in the amount of 1-50 wt. that depends on the properties of the polymer to the fiberizing, and its interaction with drugs, the type of lesion on the protected area, and so forth. For example, when used as a polymeric fibre-forming compositions of polystyrene of high molecular weight or high molecular weight methacrylate each of them is contained in the solution from 1-2 wt. cellulose acetate and perchlorovinyl 5-20 wt. Risala (without additives) 30-50 wt. or from the components of the TV can be used ethyl alcohol or other admitted to the medical use of solvents.

Such a solution polymer composition serves as one or more jets, of which an electrostatic field strength from 1 to 5 kV/cm on the surface to be protected form the coating layer microfiber or porous structure of a given thickness, and the thickness of the coating depends on the type and size of the lesion surface. The jet of polymer solution composition can be fed continuously or intermittently through a capillary or to be extruded through the die plate for forming fibre-forming polymers or porous structure that depends directly on the use of the proposed method and type of the applied coating.

For applying aseptic protective coating microfiber or porous structure is used, the device containing the forming head 1, the container 2 is applied to a grounded surface 3 solution of 4 fibre-forming polymer compositions containing aseptic preparation source 5 high voltage, one pole of which is connected to the electrode for applying voltage to the applied solution, the microcompressor 6 reported hose 7 with a capacity of 2. The second pole of the source 5 high voltage grounded. Forming head 1 contains a hollow to what aprovada 10, moreover, through the capillary 9 is a solution that is in the tank under pressure. The tank 2 is installed on the housing 8 forming head 1 and hermetically connected with him through the famous split node 11 as needed to change capacitance with the applied solutions.

The tank has a cover 12, which is equipped with nozzles 13 and 14, the pipe 13 is connected to the hose 7 microcompressor 6. For compactness of the device, the hose 7 passes through the housing 8 forming head 1. The pipe 14 is connected to the capillary 9, and the open end of the pipe 14 is placed in the vessel below the level of the inside of the solution 4. The open end of the pipe 13 can also be placed below the level in the vessel solution, as shown in Fig. 2.

In accordance with a variant of execution of the device in the lid of the vessel 2 has an additional pipe 15, one end of which is placed in the cavity of the housing 8 forming head 1, and the other end is placed in the vessel 2 above inside solution that allows couples solvent released into the vessel 2 from the solution to pass through the additional pipe 15 and to accumulate in the cavity of the housing 8 and out of the cavity in it the cleaning of the capillary. When forming the protective coating from multiple jets of the solution of the latter serves multiple forming heads or devices.

The operation of the device is as follows. For coating the patient and the device are connected to a common wire 17 to ground and the spray device is positioned at a distance of 100-300 mm to the protected surface 3, is connected to the voltage source and the microcompressor. Under the pressure developed by the microcompressor 6, the solution of one of the fibre-forming polymers and aseptic drug is delivered through the pipe 14 to the capillary 9, which voltage is 10-100 kV generator 5 high voltage.

In an electrostatic field arising between the capillary 9 and the surface to be protected 3, the solution is supplied in the form of a stream, is extruded in a thin charged thread 18, which under the action of electrostatic attraction is transported to the protected surface 3. During movement of the thread 18 of the capillary tube 9 to the surface 3 of the patient is drying yarn from the solvent and the protected surface 3 reaches the microfiber diameter of 0.1-10 μm. This fiber does not traganou the surface of the fibers under the influence of the same charge of the electrostatic field and the mutual repulsion between randomly distributed over the surface, forming a coating of a given thickness.

Small diameter fibers forms a structure that is impermeable to microorganisms and harmful dusts, but not impeding gas exchange surface to be protected or the penetration of moisture.

High speed fiberizing allows to obtain a protective coating within 2-20 minutes After which the device is disconnected from the power source and the microcompressor and removed from the patient. therapeutic effect is introduced into the solution aseptic preparations and simultaneously formed in the process of negative air ions. Electrical current process is 1-20 mA, is completely safe and the patient is not felt. The boost protective cover is retained on the surface due to the electrostatic field created in the process of formation of the coating.

P R I m m e R. On the surface of human skin by application was applied artificial nutrient medium from cultures of microorganisms. These applications were brought by the proposed method protective coating microfiber structure with a thickness of 1 mm from a solution having a viscosity of 1 PZ, conductivity 210-5Ohm/cm and containing, by weight. rizal 5% polyvinyl butyral 5% iodine 1% ethyl sa three strains of bacteria (Staphylococcus, Salmonella and esherichia), three strains of fungi (penicilli, aspergilli and debris) and four strains of imperfect fungi (Candida, Trichophyton, epidermofitony and microsporon). The protective cover is retained on the surface of the skin within 24 hours

The test results showed that the applied protective coating has antimicrobial properties (observed suppression of reproduction almost all used strains) and does not cause bio - logical skin-irritating.

Thus, the proposed method of applying a protective coating can be widely used for protection and treatment of people and animals from the surface of microbial processes (abscesses, fungal infections, and so forth), especially for ringworm, the components of the actual medical problem.

1. Method of applying protective aseptic coating by feeding on the skin of a solution of aseptic preparation, characterized in that the solution further comprises a fibre-forming polymer in quantities of 1 to 50 wt. the solution serves as at least one stream, and the coating formed in the electrostatic field of 1 to 5 kV/see

2. A device for applying casinoportalen on it forming a hollow head with capillary, one end of which is connected to the siphon tube, passed through the cover into the vessel, and the other is made free, characterized in that the device is provided with a source of high electrical voltage, one pole of which is connected to the capillary, and the other grounded, the free end of the capillary taken out of the forming head, and the pressure source in the form of microcompressor connected to the cavity of the container through the tube not reaching the level of solution in the tank.

3. The device according to p. 2, characterized in that the cavity forming head is connected with the cavity of the tank through a pipe, not reaching the level of solution in the tank, and the free end of the capillary is installed with a clearance relative to the wall of the forming head.

 

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