(2-n,n-diethylaminoethyl)-4- hydroxy -3,5di-tert - butylbenzaldehyde as coagulant emulsion rubbers

Present invention refers to new compounds of formula (1) in which X and Y can be oxygen or sulphur, each R₁, R₂ and R₃ are hydrogen atom, methyl or (CH₂)_m-CH₃, and m=1-12, n=1-12 inhibiting tumour cell growth, to a based pharmaceutical compositions (versions), and also to methods of inhibiting breast, liver and prostate cancer cell growth. The offered compounds are recovered from Antrodia camphorata.

Invention relates to solvent compositions which contain at least one organic sulphoxide of general formula (1): , where X, Y, R, R' are given in claim 1, by adding to said organic sulphoxide at least one odour masking agent which contains at least one compound selected from monoesters, di- or triesters, alcohols, ketones, aldehydes and terpenes.

Invention relates to masking the odour of organic sulphides and more specifically to alkyl or dialkyl sulphides, particularly dimethyl sulphide, as well as oxides thereof and particularly dimethyl sulphoxide by adding to said organic sulphides at least one odour masking agent which contains at least one monoester, at least one di- or triester, at least one alcohol, at least one ketone and optionally at least one terpene.

Method consists in coagulation of latex with sodium chloride and mineral acid and is characterized by that mineral acid utilized is fiber-acidifying composite obtained by treating fibrous material for 10-60 min with sulfuric acid at 40-80°C, amount of the acid constituting 0.1 to 1.0% on the weight of rubber.

Invention discloses a method for recovering synthetic rubbers from latexes stabilized by carboxylic acid soaps, which consists in action of mineral acid and organic amine coagulant on antioxidant-containing rubber latex. Organic amine coagulant is added in amount 0.01 to 1.0% in two steps: first portion constituting 50-90% of total amount of coagulant is added directly to latex and resulting mixture is stirred for at least 0.5 h at 20-70°C, after which second portion of coagulant or its mixture with mineral salt (coagulant/salt weight ratio from 1:0 to 1:15000) is fed into coagulation apparatus jointly with recycling serum at latex-to-serum weight ratio between 1:1 and 1:2. Rubber is thus obtained in the form of homogeneous porous crumb.

Coagulant based on protein component contains as additional ingredients carboxymethyl cellulose, carbamide, α- and β-amylase, fat aminoderivatives, carbamideformaldehyde resin and formalin in the next ratio (mass %): protein component 45.0-46.0; carboxymethyl cellulose 16.0-17.0; carbamide 10.1-10.2; α-amylase 9.4-0.5; β-amylase 9.4-9.5; fat aminoderivatives 8.8-8.9; carbamideformaldehyde resin 0.03-0.04; and formalin 0.02-0.03. 50 % of aminoderivatives may be replaced with alkylbenzyldimethylammonium chlorides. As protein component preferably animal- or plant-origin protein is used. Coagulant is used in 3-8 % aqueous solution form, and consumption thereof in process of fluid medium purification is 0.1-1.0 mass % based on mass of isolating rubber.

Present invention refers to emulsion rubber recovery from latex and can be used in chemical rubber industry. There is disclosed method of emulsion rubber recovery from latex through coagulation with using bivalent metal salts from magnesium chloride, magnesium sulphate, calcium chloride. Thereafter rubber crumb is separated from serum, it is followed with wringing and drying, differing that mixing latex and bivalent metal salt is preceded with pre-acidification of latex with diluted sulphuric acid concentrated 0.3-4% to pH 2.5-7.0 units. Within mixing range of acidulous latex and bivalent metal salt, concentration of the latter is kept within 0.05-0.8%, while produced rubber crumb is wrung out thus maintaining pH of wringing water within 2.5-6.9 units with sulphuric acid supplied to pre-acidification of latex.

invention refers to manufacture of synthetic rubbers that are obtained by means of emulsion copolymerization, notable to the stage of their extraction from latex, and can be applied in petrochemical industry. In the salt-free congelation method rubbers that contain leukanol-oil dispersing agent are employed. The rubbers are obtained by emulsion copolymerization of butadiene with the monomers of the vinylic row. As a coagulating agent, quaternary ammonium compounds are used that are based on resin acids and colophony Biozic by means of introduction of 3-5 kg of an active substance into the latex per 1 t of the rubber.

Method of extracting butadiene-nitrile rubber from latex is carried out by feeding sodium sulphite or sodium bisulphite or sodium pyrosulphite in amount of 0.05-0.8 wt % per latex, into a stream of latex degassed beforehand, into which an antioxidant emulsion is also fed. Further, the stream of latex, containing sulphite, is directed into a coagulation apparatus into which aqueous sulphuric acid and an organic amine coagulant in form of a quaternary polymer ammonium salt are also simultaneously fed, said salt being selected from: polydimethyl diallyl ammonium chloride, a methacrylamide and dimethyl aminoethyl methacrylate hydrochloride copolymer, and polydiethyl aminoethyl methacrylate hydrochloride. The amount of the polymer ammonium salt varies from 0.2-0.5 wt %, per rubber, depending on content of leukanol content in latex in the range of 0.1-0.4 wt %, per rubber, at coagulation pH 3-6 and temperature 30-70°C.

Described is nitrile rubber which contains repeating units of at least one α,β-unsaturated nitrile and at least one conjugated diene, and also contains magnesium ions in concentration of 100-180 ppm and calcium ions in concentration of 50-145 ppm, respectively, with respect to nitrile rubber. Described is a method of producing said nitrile rubber via emulsion polymerisation of at least one α,β-unsaturated nitrile, at least one conjugated diene and optionally one or more other copolymerisable monomers selected from a group comprising α,β-unsaturated mono- or dicarboxylic acids, esters and amides thereof, in the presence of at least one molecular weight regulator, with the latex which is obtained during polymerisation and contains nitrile rubber being subjected to coagulation and the coagulated nitrile rubber subsequently being washed, wherein (i) the latex obtained during emulsion polymerisation has a pH of at least 6 before the coagulation, (ii) coagulation of the latex is carried out using at least one magnesium salt, up to 40 wt % of which is optionally replaced with a calcium salt, as precipitant, (iii) the coprecipitant used during coagulation of latex is gelatine, (iv) temperature of latex before reacting with the coprecipitant (iii) is kept higher than 50°C, and then raised to 100°C, and (v) coagulation of latex and/or treatment of the coagulated latex is carried out using water containing calcium ions, under the condition that coagulation is carried out without a calcium salt as a precipitant. Treatment of nitrile rubber obtained using the method described above is described, wherein nitrile rubber is subjected to (i) either a metathesis reaction only or (ii) a metathesis reaction and subsequent hydrogenation, or (iii) hydrogenation only, to obtain optionally hydrogenated nitrile rubber. Described is use of said nitrile rubber, optionally hydrogenated nitrile rubber, to obtain vulcanised mixtures, obtained by mixing at least one nitrile rubber or at least one optionally hydrogenated nitrile rubber, at least one cross-linking agent and optionally other additives. Described is a method of making moulded articles, such as a seal, a cap, a hose or a diaphragm, in particular an O-ring seal, a flat seal, a dynamic seal, a sealing sleeve, a sealing cap, a cap for protection from dust, a plug seal, a thermal insulation hose (with or without a PVC additive), an oil cooler hose, an air hose, a servo control hose or a pump diaphragm, through vulcanisation during moulding, via pressure casting of said vulcanised mixture.

Described is nitrile rubber which contains repeating units of at least one α,β-unsaturated nitrile and at least one conjugated diene and has chlorine content in the range of 4 to 25 ppm with respect to nitrile rubber. Described is a method of producing said nitrile rubber by emulsion polymerisation of at least one α,β-unsaturated nitrile, at least one conjugated diene and optionally one or more other copolymerisable monomers selected from a group comprising α,β-unsaturated mono- or dicarboxylic acids, esters and amides thereof, in the presence of a molecular weight regulator, with the latex which is obtained during polymerisation and contains nitrile rubber being subjected to coagulation and the coagulated nitrile rubber subsequently being washed, wherein (i) the latex obtained during emulsion polymerisation has a pH of at least 6 before the coagulation, (ii) coagulation of the latex is carried out using at least one salt of a mono-, di- or trivalent metal, which is optionally a chloride, as precipitant, (iii) coagulation of the latex is carried out in the presence of polyvinyl acetate, which is optionally partially or fully saponified, as coprecipitant, and (iv) coagulation of latex and/or treatment of the coagulated latex is carried out using water containing chloride ions under the condition that the salt of the mono-, di- or trivalent metal (ii) is not a chloride. A method of treating nitrile rubber obtained using the method described above is described, wherein nitrile rubber is subjected to (i) either a metathesis reaction only or (ii) a metathesis reaction and subsequent hydrogenation, or (iii) hydrogenation only, to obtain optionally hydrogenated nitrile rubber. Described is use of said nitrile rubber, optionally hydrogenated nitrile rubber, to obtain vulcanised mixtures, obtained by mixing at least one nitrile rubber or at least one optionally hydrogenated nitrile rubber, at least one cross-linking agent and optionally other additives. Described is a method of making moulded articles in form of a seal, a cap, a hose or a diaphragm, in particular an O-ring seal, a flat seal, a dynamic seal, a sealing sleeve, a sealing cap, an oil cooler hose, a hydraulic booster hose, an air conditioner hose, a thermal insulation hose, a diaphragm for hydro bearings or a diaphragm for a diaphragm pump, through vulcanisation during moulding, preferably via pressure casting of said vulcanised mixture.

Nitrile rubber contains repeating units of at least one α,β-unsaturated nitrile and at least one conjugated diene and has ionic index in the range of 7-26 ppm×mol/g. The nitrile rubber is obtained by emulsion polymerisation. The obtained latex, which contains nitrile rubber, is coagulated and the coagulated nitrile rubber is washed. Polymerisation is carried out in the presence of at least one alkylthiol. Before coagulation, the pH of the latex is set to at least 6, and coagulation is then carried out in the presence of at least one salt of a monovalent metal. The latex coagulation temperature ranges from 60 to 90°C and the washing temperature ranges from 50 to 90°C. The obtained nitrile rubber is used to obtain curable mixtures which contain said rubber and at least one cross-linking agent. The curable mixtures are cured by moulding to obtain moulded articles.

Method of separating emulsion polymerisation rubber involves coagulation of rubber latex in an acidic medium in the presence of a coagulant - polydiallyl dimethylammonium chloride. An aqueous solution of the coagulant with concentration of 4.3-4.8% is premixed with serum in a flow mixer in ratio of coagulant to serum of (0.115-0.150):(30-45) m³/h and then fed into a coagulation apparatus from the bottom simultaneously with sulphuric acid solution. Latex is fed into the coagulation apparatus from the top in ratio of latex to serum of 1:(2.4-2.7). Coagulation is carried out in an acidic medium at pH 5.4-6.3 and temperature 50-60°C. After coagulation, rubber crumbs flow under gravity into a maturing tank, for pressing, drying and briquetting.

Invention is dealing, in particular, with thermally processed tetrafluoroethylene copolymers having predominantly spherical shape for at least 95 wt % of material. Median microsphere size lies within a range of 25 μm to 2 mm and bulk density between 0.5 and 1.1 g/cm³. Invention also concerns coagulation apparatus and microsphere preparation process.

Invention relates to the continuous method for preparing polytetrafluoroethylene (PTFE) or modified PTFE finely divided powders. The continuous method for preparing PTFE or modified PTFE finely divided powders involves the following steps: (a1) dilution of PTFE-latex of modified PTFE-latex prepared in polymerization in the dispersion-emulsion to the concentration from 5 to 25 wt.-% of PTFE or modified PTFE with possible filtration of the prepared diluted latex; (b1) molding latex with inert gas to the relative pressure with respect to atmosphere pressure in the range 3-40 kg/cm² (0.3-4 MPa); (c1) addition of acid electrolyte solution to latex in the line-flow mixer at pH value 1-4; (d1) feeding the latex flow from the mixer through capillary tube under condition of turbulent current with the Reynolds number above 3000; (e1) gel prepared at step (d1) is coagulated onto granules at mechanical stirring with the specific power 1.5-10 kWt/m³ and stirring is maintained up to flotation of finely divided powder; (f1) below water is separated from the finely divided powder. PTFE of modified PTFE finely divided powders that can't be processed by thermal method prepared by abovementioned method show the following indices: apparent density is ≥ 470 g/l; average diameter of particles (D₅₀) is above 200 mcm; distribution of particles by diameter determined as ratio between particles mass with diameter from 0.7 to 1.3 times with respect to average particles diameter and the total particles mass above 50%. Invention provides preparing powders without using the complex and expensive equipment, and powders possess the improved fluidity and show the apparent density and narrow distribution of particles by the diameter index.

Present invention refers to emulsion rubber recovery from latex and can be used in chemical rubber industry. There is disclosed method of emulsion rubber recovery from latex through coagulation with using bivalent metal salts from magnesium chloride, magnesium sulphate, calcium chloride. Thereafter rubber crumb is separated from serum, it is followed with wringing and drying, differing that mixing latex and bivalent metal salt is preceded with pre-acidification of latex with diluted sulphuric acid concentrated 0.3-4% to pH 2.5-7.0 units. Within mixing range of acidulous latex and bivalent metal salt, concentration of the latter is kept within 0.05-0.8%, while produced rubber crumb is wrung out thus maintaining pH of wringing water within 2.5-6.9 units with sulphuric acid supplied to pre-acidification of latex.

Rubber is extracted from latex continuously by mixing latex with a coagulant. Consumption of coagulant is varied depending on the given turbidity value of serum (primary serum), which is maintained by the amount of coagulant fed. The given turbidity value of primary serum is adjusted depending on the turbidity of the serum released (secondary serum) towards the minimum consumption of coagulant to obtain minimum turbidity of the released serum.

Method of extracting butadiene-nitrile rubber from latex is carried out by feeding sodium sulphite or sodium bisulphite or sodium pyrosulphite in amount of 0.05-0.8 wt % per latex, into a stream of latex degassed beforehand, into which an antioxidant emulsion is also fed. Further, the stream of latex, containing sulphite, is directed into a coagulation apparatus into which aqueous sulphuric acid and an organic amine coagulant in form of a quaternary polymer ammonium salt are also simultaneously fed, said salt being selected from: polydimethyl diallyl ammonium chloride, a methacrylamide and dimethyl aminoethyl methacrylate hydrochloride copolymer, and polydiethyl aminoethyl methacrylate hydrochloride. The amount of the polymer ammonium salt varies from 0.2-0.5 wt %, per rubber, depending on content of leukanol content in latex in the range of 0.1-0.4 wt %, per rubber, at coagulation pH 3-6 and temperature 30-70°C.

Described is nitrile rubber which contains repeating units of at least one α,β-unsaturated nitrile and at least one conjugated diene, and also contains magnesium ions in concentration of 100-180 ppm and calcium ions in concentration of 50-145 ppm, respectively, with respect to nitrile rubber. Described is a method of producing said nitrile rubber via emulsion polymerisation of at least one α,β-unsaturated nitrile, at least one conjugated diene and optionally one or more other copolymerisable monomers selected from a group comprising α,β-unsaturated mono- or dicarboxylic acids, esters and amides thereof, in the presence of at least one molecular weight regulator, with the latex which is obtained during polymerisation and contains nitrile rubber being subjected to coagulation and the coagulated nitrile rubber subsequently being washed, wherein (i) the latex obtained during emulsion polymerisation has a pH of at least 6 before the coagulation, (ii) coagulation of the latex is carried out using at least one magnesium salt, up to 40 wt % of which is optionally replaced with a calcium salt, as precipitant, (iii) the coprecipitant used during coagulation of latex is gelatine, (iv) temperature of latex before reacting with the coprecipitant (iii) is kept higher than 50°C, and then raised to 100°C, and (v) coagulation of latex and/or treatment of the coagulated latex is carried out using water containing calcium ions, under the condition that coagulation is carried out without a calcium salt as a precipitant. Treatment of nitrile rubber obtained using the method described above is described, wherein nitrile rubber is subjected to (i) either a metathesis reaction only or (ii) a metathesis reaction and subsequent hydrogenation, or (iii) hydrogenation only, to obtain optionally hydrogenated nitrile rubber. Described is use of said nitrile rubber, optionally hydrogenated nitrile rubber, to obtain vulcanised mixtures, obtained by mixing at least one nitrile rubber or at least one optionally hydrogenated nitrile rubber, at least one cross-linking agent and optionally other additives. Described is a method of making moulded articles, such as a seal, a cap, a hose or a diaphragm, in particular an O-ring seal, a flat seal, a dynamic seal, a sealing sleeve, a sealing cap, a cap for protection from dust, a plug seal, a thermal insulation hose (with or without a PVC additive), an oil cooler hose, an air hose, a servo control hose or a pump diaphragm, through vulcanisation during moulding, via pressure casting of said vulcanised mixture.

Described is nitrile rubber which contains repeating units of at least one α,β-unsaturated nitrile and at least one conjugated diene and has chlorine content in the range of 4 to 25 ppm with respect to nitrile rubber. Described is a method of producing said nitrile rubber by emulsion polymerisation of at least one α,β-unsaturated nitrile, at least one conjugated diene and optionally one or more other copolymerisable monomers selected from a group comprising α,β-unsaturated mono- or dicarboxylic acids, esters and amides thereof, in the presence of a molecular weight regulator, with the latex which is obtained during polymerisation and contains nitrile rubber being subjected to coagulation and the coagulated nitrile rubber subsequently being washed, wherein (i) the latex obtained during emulsion polymerisation has a pH of at least 6 before the coagulation, (ii) coagulation of the latex is carried out using at least one salt of a mono-, di- or trivalent metal, which is optionally a chloride, as precipitant, (iii) coagulation of the latex is carried out in the presence of polyvinyl acetate, which is optionally partially or fully saponified, as coprecipitant, and (iv) coagulation of latex and/or treatment of the coagulated latex is carried out using water containing chloride ions under the condition that the salt of the mono-, di- or trivalent metal (ii) is not a chloride. A method of treating nitrile rubber obtained using the method described above is described, wherein nitrile rubber is subjected to (i) either a metathesis reaction only or (ii) a metathesis reaction and subsequent hydrogenation, or (iii) hydrogenation only, to obtain optionally hydrogenated nitrile rubber. Described is use of said nitrile rubber, optionally hydrogenated nitrile rubber, to obtain vulcanised mixtures, obtained by mixing at least one nitrile rubber or at least one optionally hydrogenated nitrile rubber, at least one cross-linking agent and optionally other additives. Described is a method of making moulded articles in form of a seal, a cap, a hose or a diaphragm, in particular an O-ring seal, a flat seal, a dynamic seal, a sealing sleeve, a sealing cap, an oil cooler hose, a hydraulic booster hose, an air conditioner hose, a thermal insulation hose, a diaphragm for hydro bearings or a diaphragm for a diaphragm pump, through vulcanisation during moulding, preferably via pressure casting of said vulcanised mixture.

Invention relates to a method of producing fine polytetrafluoroethylene powder, as well as fine powder obtained using said method. The method of producing fine polytetrafluoroethylene powder involves emulsion polymerisation of tetrafluoroethylene in the presence of an aqueous medium, a fluorinated surfactant and a radical polymerisation initiator to obtain an aqueous emulsion of polytetrafluoroethylene and coagulation thereof in the presence of at least one apparent density-reducing compound selected from a group consisting of ammonia, an ammonium salt and urea, in amount ranging from 0.4 to 10 pts.wt per 100 pts.wt polytetrafluoroethylene. The fine polytetrafluoroethylene powder obtained using said method has standard specific mass from 2.140 to 2.180 and paste extrusion pressure from 10 to 25 MPa.