Quaternary compounds thereof (C07D213/20)

Method of producing 1-(adamantyl-1)-pyridinium bromide

Present invention relates to a method of producing 1-(adamantyl-1)-pyridinium bromide by reacting 1-bromoadamantane with pyridine in molar ratio 1:1-2 in the presence of 1-10 mol % 3-hydroxypyridine at 90-120°C for 10-40 hours.

Method of producing solid triphenyl boron-pyridine or adduct thereof

Described is a method of preparing spherical particles of solid triphenyl boron-pyridine (TPBP) by separately feeding into an intensely stirred reaction zone (i) a stream of pyridine, and (ii) a stream containing a solution of a sodium hydroxide-triphenyl-boron adduct (TPBA), as a result of which total concentration of TPBA in the merged streams ranges from 1 wt % to 6 wt %, and simultaneously removing the product stream from said reaction zone and extracting TPBP particles.

Rac- n-[2,3-di(tetradecyloxy)prop-1-yl]pyridinium bromide as agent for delivering nucleic acids into mammal cells

Invention relates to a novel chemical compound, specifically to rac-N-[2,3-di(tetradecyloxy)prop-1-yl]pyridinium bromide, which can deliver nucleic acids into mammal cells: .

Fluorinated 1,4-naphthoquinone derivatives having cytotoxic effect on human cancer cells in culture

Invention relates to an agent, which is in form of fluorinated 1,4-naphthoquinone derivatives of general formula (I) which have cytotoxic effect on human cancer cells in a culture. In general formula (I) 1) R1=NHC(CH3)3, R2, R3=F; 2) R1=NHCH2CH2SCH3, R2, R3=F; 3) R1=N(CH2CH2)2, R2, R3=F; 4) R1=N(CH2CH2)2, R2, R3=F; 5) R1=NHCH2CH2CH2CH3, R2, R3=F; 6) R1=NHC6H5R2, R3=F; 7) R1=H(CH3)CH2CH2OH, R2, R3=F; 8) R1, R3=NHCH2CH2CH2CH3, R2=F; 9) R1=N(CH2CH2OH)2, R2, R3=F; 10) R1=NHC6H5, R2=CH3, R3=F; 11) R1=OCH3, R2, R3=F; 12) R1=NH(CH2)2SS(CH2)2NH(2-pentafluoro-1,4-naphthoqunonyl), R2, R3=F; 13) R1=NHC2H5, R2, R3=F; 14) R1=N+C5H5, R2=O; R3=F; 15) R1=NHCH2CH2OH, R2,R3=F; 16)R1, R2=OCH3, R3=F.

Method of obtaining organic salts, which contain anions of bis(perfluoroalkyl)phosphinate

Claimed invention relates to method of obtaining organic salts, which contain anions of bis(perfluoroalkyl)phosphinate and can be applied in organic synthesis. Difference of claimed method lies in the fact that it includes carrying out reaction of tris(perfluoroalkyl)phosphinoxide with alcohol and organic base, stronger than alcohol.

Ionic liquids containing anions [n(cf₃)₂]^-

Present invention concerns the salts containing bis(trifluoromethyl)imide anions and saturated, partially or completely unsaturated heterocyclic cations, method of production and application thereof as ionic liquids.

Method of production of surfactant alkoxy-(alkyl-substituted) methylpyridin chlorides

Proposed method includes alkylation of pyridin by alkyl-substituted chloromethyl ethers which are obtained through interaction of three starting components: higher alcohols or their fractions, carbonyl compound which is just aldehyde or ketone and chlorinating agent containing sodium chloride and sulfuric acid.

Method for preparing phenyl-substituted derivatives of pyridine labeled with tritium

Invention relates to a method for preparing N-phenylpicolinium salts and phenyl-substituted picolines labeled with tritium by phenyl ring of the general formula: [CH3C5H4N+C6H* 5]BF- 4 and CH3C6H* 5C5H3N. Method involves arylation of 2-, 3- and 4-picolines with free phenyl cations obtained in beta-decay of tritium in composition of two-fold labeled benzene in the presence of potassium tetrafluoroborate in the closed system. Method provides improving method of synthesis of labeled benzene and to use ion-molecular reaction of tritium-labeled phenyl cations for simultaneous, simple and a single-step synthesis of N-phenylpicolinium salts and phenyl-substituted picolines labeled with tritium that can be used in investigations of metabolism of biologically active heterocyclic derivatives.

Pyridinium hexafluorophosphate preparation method

Invention relates to technology of preparing pyridinium hexafluorophosphate, which is convenient intermediate for synthesis of lithium hexafluorophosphate used as ionic electrolyte component for lithium chemical power sources. Pyridinium hexafluorophosphate is prepared via reaction phosphorus pentachloride with fluorination agent such as ammonium hydrodifluoride followed by treatment of resulting intermediate with pyridinium salt solution.

Ionic liquids ii

Invention relates to new ionic liquids designated for using in electrochemical cells and in organic synthesis. Invention describes ionic liquids of the general formula: K+A- (I) wherein K+ represents one of cations of the group consisting of the following formulae: wherein R1-R5 can be similar or different and can be bound to one another by a simple or double bond also, and each of them separately or in common can represent the following values: hydrogen atom (H), halogen atom, (C1-C8)-alkyl radical that can be partially or completely substituted with the following groups but preferably with fluorine atom (F), chlorine atom (Cl), N-[CnF(2n+1-x)Hx]2, O-[CnF(2n+1-x)Hx], SO2-[CnF(2n+1-x)Hx] or CnF(2n+1-x)Hx wherein 1 < n < 6 and 0 < x < 2n+1; A- means anion taken among the group consisting of [PFx(CyF(2y+1-z)Hz)6-x]- wherein 1 ≤ x ≤ 6, 1 ≤ y ≤ 8 and 0 ≤ z ≤ 2y+1. Invention provides the development of ionic liquids showing broad range of liquid state, high thermal resistance and low corrosive activity.

Method of preparing corrosion inhibitor-bactericide for hydrogen sulfide-containing and acidic media

Invention, in particular, relates to protection of oil-field equipment to suppress vitality of microorganisms and to inhibit corrosion in hydrogen sulfide-containing and acidic media, in oil production, transportation, and storage systems as well as in flooded formations. Task is solved by that, in a method of preparing corrosion inhibitor-bactericide, alkyl-substituted pyridines are brought into reaction alkyl bromides at elevated temperature, said alkyl-substituted pyridines being picolines or picoline fractions at molar ratio of picolines or picoline fractions to C10-C16-alkyl bromides 1.05:1. Picolines or picoline fractions are introduced into three-step reaction each time by 0.35 mole with time interval 40-50 min, while overall reaction proceeds for 2-5 h at 120-140°C. If necessary, reaction product is mixed with solvent to form 20-70% reagent solution.