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Biocompatible composite and its application Invention relates to medicine, namely to composite material, including biocompatible and bioabsorbable glass, biocompatible and bioabsorbable matrix polymer and binding agent, capable of formation of covalent bonds. Composite includes compatibiliser, with at least 10% of structural units of compatibiliser being identical to structural units of matrix polymer, and molecular weight of compatibiliser being less than 30000 g/mol. Described is application of claimed composite, medical device, which contains said composite, and method of composite obtaining. |
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Histo-equivalent bioplastic material What is described is a histo-equivalent bioplastic material comprising a carrier in the form of a matrix that is presented by a native form of hyaluronic acid. The histo-equivalent bioplastic material is prepared by mixing 1.5% hyaluronic acid and 5% peptide complex in the following proportions: 80-90 ml and 10-20 ml, respectively to form a viscous elastic gel that is placed on a mould carrier and exposed to ultraviolet photopolymerisation in a laminar flow hood for 5-7 hours, and then transferred onto a perforation apparatus with the finished material being perforated and notched. |
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Method for making bioresorbed small-diameter hybrid vascular graft Invention refers to medicine and tissue engineering, and may be used in cardiovascular surgery for small-vessel bypasses. A vascular graft is made by two-phase electrospinning with the staged introduction of the ingredients into the polymer composition. |
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Micro-nanostructured bioplastic material Invention refers to medicine, namely combustiology, plastic surgery, cosmetology, and can find application as a bioplastic material for skin defect replacement and regeneration stimulation. What is described is a micro-nanostructured bioplastic material which is based on a nanostructured matrix formed of hyaluronic acid; it contains proteoglycans, glycoproteins, fibrous proteins and antiseptic in the following ratio (per 100 ml): hyaluronic acid - 30-20; proteoglycans - 20-30; glycoproteins -10-15, fibrous proteins - 10-15, antiseptic - 5-10; solvent (water) - the rest. |
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Invention refers to polymer composites with the special characteristics used as medical implants, transformed structures, thermal activators and the other commercial structures. The composite comprises a polymer matrix with working temperatures exceeding fibre configuration recovery temperature, and tensile extension min. 2%, reinforced with the elements presented in the form of fibres extended in one or more directions with the fibre length min. 3 times more than the in-between distance, made of a thermal shape memory alloy. |
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Invention refers to medicine, namely transplantology, traumatology, general surgery, dentistry, combustiology, plastic surgery, cosmetology. The organ-specific regenerant GI contains a fibrin matrix with thrombin, cryoprecipitate prepared of quarantine fresh-frozen donor plasma. The fibrin matrix is nanostructured and contains thrombolysate enriched by growth factors and cytokines. Cryoprecipitate, thrombolysate and human thrombin in the regenerate are found in equal proportions in the following quantitative relation of the ingredients, mg: cryoprecipitate - 1; thrombolysate - 1; human thrombin -1 0.9%; normal saline - 2 10%; calcium chloride brine -1. |
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Invention refers to medicine, namely combustiology, plastic surgery, cosmetology, and can find application as a bioplastic material for skin defect replacement and regeneration stimulation. In the bioplastic material containing a matrix base made of a native form of hyaluronic acid, a frame of the bioplastic material is prepared by the layered lyophilisation of the matrix material to form a space 0.5 to 10 cm thick with fibres of the native form of hyaluronic acid being directed in the porous order and their cells being enriched with thrombocytic lysate with thrombocyte count 1×109 thromb/ml. |
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Invention relates to medicine, namely to surgery and can be used in hernioplasty. For this purpose 40-130 ml of autoblood are sampled during operation, centrifuged for 15-20 minutes, erythrocyte layer is removed. 10% solution of calcium chloride is added to remaining leukocyte-platelet layer of centrifugate and blood plasma. Mixture is shaken up. Mesh allomaterial, prepared by the size of operation wound, is soaked with mixture and sewn in the area of hernial ring. Operation wound is sewn tightly. |
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Fibre-reinforced composite materials and method of obtaining them Group of inventions relates to fibre-reinforced composite materials, in particular to oriented in application composite materials, used in dental and medical fields/devices. Solidified fibre-reinforced composite material includes compounded with each other: system of monomers, containing, at least, one solidified monomer, system of filling agents and initiator(s) of polymerisation, and/or polymerisation accelerator(s). System of filling agents contains, at least, one prepreg, containing 0.5-100 mm long fibres, and polymer matrix, and optionally, at least, one powder filling agent, prepreg being located in form of parts, which are 0.5-100 mm long. As fibre, preferably fibre glass is used. Powder filler is selected from common powder filling agents and nanomeric powder filling agents. Claimed is method of said material obtaining and its application in dental and medical field and corresponding devices, in particular, for filling in dental cavities, as filling composites, temporary and semi-permanent composite material for crowns and bridges, filling and binding materials. |
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Biological patch and method of its production Invention relates to medicine. Described is patch for application in surgery, produced by method, which includes stages of selection of animals tissue, which contains substrate, diametrical linking and fixation of substrate, minimisation of substrate agents activity, substrate tanning and binding of active layer to substrate. |
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Biological wound covering and method of its production Invention relates to medicine. Described is biological wound covering, produced by method, which includes stages of selection of animal tissue, which contains substrate, of diametrical linking and fixation of substrate, minimisation of substrate agents activity and binding of active layer to substrate. |
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Artificial biological implant for nerve guide membrane and method of its manufacturing Invention relates to medicine. Described is artificial biological implant for nerve guide membrane, made by method, which contains stages of selection of connective membrane of animal, transverse sewing and fixation of membrane, minimisation of activity of membrane antigens, tanning of membrane, connection of active layer to internal surface of membrane, cutting membrane to required shape and size, placement of cut membrane on rod-shaped matrix in such a way that cut membrane took cylindrical shape, and attachment of spiral braid (2) to external surface of membrane. |
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Nanostructured bioplastic material In a nanostructured bioplastic material containing a native form of hyaluronic acid, a base is nanostructured hyaluronic acid produced by photochemical cross-link and having a cellular texture in the range of 50 to 100 nm. |
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Bioplastic material includes matrix base of fibrous structure which is a native form of hyaluronic acid and forms a flexible plate. The bioplastic material contains antimicrobial substances. |
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Polymer antifriction composition for biomedical purposes Present invention pertains to compositions, with low coefficient of friction for use in friction units of living organisms. Proposal is given of an antifriction composition, containing, as polymer binding mixture (with ratio of components in the binder): methyl methacrylate monomer (27-36 mass units), polymethyl methacrylate polymer powder (72-64 mass units), initiator - benzoyl peroxide 1 mass units (polymer binder A); or a mixture (with ratio of components in the binder): methyl methacrylate (27-36 mass units), copolymer powder (72-64 mass units) with the following content of components: methyl methacrylate - 89 mass units, ethyl methacrylate - 8 mass units, methyl methacrylate - 2 mass units, as well as initiator-benzoyl peroxide - 0.6-1.5 mass units (polymer, binder B) and ultrahigh-molecular polyethylene with 1·106 - 12·106 dalton molecular weight, in powder form (2-15 mass units per 85-98 mass units of polymer binder). Compared to the prototype, the value of coefficient of friction decreases by 2-4 times. |
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Material for medical or veterinary needs, method of its obtaining and use Material which is used in the form of a detail, executed by formation by moulding is described, and it represents the biocompatible binding, containing one or several bonds providing addition of calcium or phosphorus, differing that it is exposed to operations of superficial clearing intended for deducing on a surface. This material is preferably used for manufacturing of ventplants or osteal prostheses. |
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Carcasses and method for producing the carcasses for carrying out human bone tissue engineering Device has composite materials containing biologically active microparticles stimulating human bone tissue regeneration. Silicon, calcium and phosphorus particles combination is used in given carcasses as biologically active substance stimulating human osteoblast proliferation and differentiation and promoting osteogenesis and new bone calcification. Beside that, organic polymer is used in given carcasses as carrier having three-dimensional structure and external anatomical shape. It shows several properties compatible with bone regeneration and blood vessel neogenesis. |
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Claimed composition contains calcium sulfate and viscous biopolymers and can be easily introduced into defect part of damaged bone. Composition of present invention is capable of penetration into adjacent organs and is useful as physiologically acceptable filling material for bone concretion. |
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Biomedicine material composition, method for production thereof and biomedicine material Claimed composition contains polymer binder, namely mixture of polymethylmethacrylate or methylmethacrylate copolymer with methylacrylate and monomer methylmethacrylate in ratio of polymer part to monomer from 1:0.3 to 1:0.5 mass pts (50-72 mass pts); peroxide initiator (0.05-0.5 mass pts): carbon continuous fibers of 200-1000 filaments made of hydratcellulose fiber of polyacrylonitrile fiber (2-10 mass pts); and hydroxyapatite as filler (25-40 mass pts). Method for production of material from claimed composition useful in manufacturing of jowl implants also is disclosed. |
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Resin composition for leuprolide delivery of improved effectiveness Claimed composition contains biodegradable thermoplastic polyester essentially insoluble in aqueous medium or body fluid. Composition also contains biocompatible polar aprotic solvent which is compatible with aqueous medium or body fluid in blendability and dispersability. Fluid composition also contains leuprolide acetate. Method for production of fluid composition also is disclosed. Invention also relates to solid biodegradable implant forming in situ in patient body after injection of fluid composition to patient. Said implant allows dissipation of biocompatible polar aprotic solvent. Invention also relates to kit. |
Another patent 2528943.