Plaque detection by flow probe
SUBSTANCE: dental device with a flow probe is provided, which configuration is such that the passage of fluid (30) through the open port (136, 2604) of the distal tip (112, 112') of the probe provides detection of the substance (116) on the dental surface (31, 33) based on the measurement of the signal correlated with the substance, at least partially impeding fluid (30) passage through the open port (136, 2604). The device (100, 100') includes a proximal pumping portion (124) and at least one distal portion (110) of the probe, configured to be immersed in another fluid (11), for example water in the toothpaste foam. At least one distal probe portion (110) may include two or more components for that.
EFFECT: improvement of efficiency and reliability.
4 cl, 41 dwg, 1 tbl
SUBSTANCE: group of inventions relates to medicine. System for supply of intravenous liquid contains disposable set of intravenous liquid supply and intravenous pump. Disposable set of intravenous liquid supply contains sensor for perception of supplied liquid parameter when it is placed in zone of intravenous liquid perception and connected with sensor transceiver for wireless connection with intravenous pump, made with possibility of obtaining energy from intravenous pump and providing energy supply to sensor only at the expense of energy, obtained by wireless method. Device for intravenous liquid supply contains disposable and reusable segments. Disposable segment contains input and output of liquid, connected via liquid, sensor for measuring parameter of supplied liquid in point between input and output, as well as connected with sensor wireless transceiver for wireless transmission of measured values of supplied liquid parameters. Reusable element is made with possibility of reception and wireless connection with disposable part, remaining isolated with respect to liquid from contact with liquid, and contains central processor for wireless control of sensor working parameter. Wireless scanning is performed in order to detect wireless transceiver of disposable set of intravenous liquid supply, loaded into pump for liquid supply. Data of detected disposable set of intravenous liquid supply are downloaded into processor in order to start session of liquid supply. Detected disposable set of intravenous liquid supply is programmed for work with pump for liquid supply. Monitoring of liquid supply session is realised with application of wireless channel of connection with said disposable set of intravenous liquid supply.
EFFECT: application of inventions will make it possible to increase accuracy of measuring liquid parameters and reduce potential threat of electric shock.
21 cl, 7 dwg
SUBSTANCE: invention relates to medicine, namely ophthalmology. A method consists in using a portable dispensing apparatus with an automatically controlled spray dose number, comprising an electronic unit and a hydraulic unit. In the electronic unit, a piezoelectric detector fixed on an orbital bone, a clipping amplifier, a standard pulse shaper, an integrator, a threshold circuit with two thresholds, a feedback is established of a blink rate and the dose number of a medicated mixture injected into conjunctival cavities by means of microcatheters.
EFFECT: using the invention provides regular dosing artificial eye moistening in dry eye syndrome for preventive and therapeutic purposes.
SUBSTANCE: group of inventions refers to medicine. A system for monitoring and control of blood glucose levels comprises a blood glucose metre, an input device for obtaining at least one measured blood glucose value, at least one insulin dose supplied at the moment to the blood flow by at least one insulin feed system, and if observing at least one nutritional value supplied to the blood flow either directly, or indirectly by at least one supply feeder; a calculator for obtaining a new insulin dose and a new nutritional value depending on the effect on blood glucose values and depending on the pre-set blood glucose value; new nutritional values are calculated if the supply feeder terminates the supply or changes the supply dosage, and an output device for drawing the new insulin doses and the nutritional values. A method for monitoring and control of the blood glucose values involves the following stages: including at least one supply feeder for direct or indirect supply to the blood flow; measuring the blood glucose values; determining at least one nutritional values from data series from the supply feeder to a control unit; transferring the measured blood glucose values in the blood flow to the control unit; calculating the insulin dose by means of a calculating unit, and if observing the nutritional value depending on the effect of the blood glucose levels and depending on the pre-set blood glucose levels with the new nutritional values calculated if the supply feeder terminated the supply or changes the supply dosage, and drawing the new insulin dosage and the calculated nutritional values by means of the output device.
EFFECT: enhancing the system for monitoring and control of the blood glucose levels.
18 cl, 7 dwg
SUBSTANCE: group of inventions relates to medical injection device for application with cartridge. Device contains spring-loaded means, configured for storing energy during procedure, which precedes injection, drive element, made with possibility of moving piston of said cartridge towards exhaust end of cartridge, with application to drive element during injection of effort, created by spring-loaded means when energy, stored in said device is released; component for initiation of release of energy by spring-loaded means, thus starting introduction of dose. Sensor is made with possibility of detecting positional information, which relates to drive element or component, connected to drive element. Electronic circuit is connected with sensor, intended for processing signals, which are formed by sensor and is made with possibility of determining data about speed of dose introduction on the basis of signals, formed by sensor, compare data about said speed with earlier determined data about speed and realise controlling influence, when speed of dose introduction, determined during injection, goes beyond the range of normal values. Structurally different version of device is described.
EFFECT: reducing risk of inaccurate dose.
16 cl, 4 dwg
SUBSTANCE: invention refers to medical equipment, namely to devices for drug delivery to a patient, particularly to devices for subcutaneous drug or substance delivery, and using energy sources for providing more effective introduction of drugs. The device for therapeutic substance delivery to a patient's body comprises an infusion catheter, a catheter attachment element, a case, a therapeutic element and a controller. The infusion catheter is presented to be introduced into body tissue at an introduction area on a patient's body and to deliver the therapeutic substance into the patient's body within the infusion area. The infusion area covers a body tissue volume surrounding the introduction area. The catheter attachment element is presented to be attached to patient's skin and to attach the infusion catheter to skin. The case comprises the device for drug delivery designed for introducing the therapeutic substance into the infusion catheter for delivering the therapeutic substance within the infusion area, and a sensor integrated in the case and detecting the infusion of the therapeutic substance. The therapeutic element is presented to apply the therapy close to the infusion area for changing pharmacokinetic and/or pharmacodynamic profile of the therapeutic substance. The controller is presented to enable data exchange with the therapeutic element and to begin the therapy with the therapeutic element after the beginning of the infusion of the therapeutic substance has been found.
EFFECT: invention provides effective and well-timed insulin delivery into blood thereby preventing or reducing hyperglycemic and hypoglycemic attacks.
21 cl, 50 dwg
SUBSTANCE: invention relates to field of medicine, namely, to ophthalmology, and concerns methods of introduction of medicinal substances in eye tunics and media. Method ensures rational (economical) spending of medications (mixtures) during introduction of medicinal substances by means of doser into subtaneous space due to automatic regulation of mixture concentration in lesion focus. Implant, consisting of strip of collagen sponge 15x10 mm in size and connected with it polychlorvinyl catheter, is introduced into subtaneous space. In sponge two microelectrodes 1.5x1 mm in size, with output from catheter for pickup of potential difference (of electric signal), whose value changes depending on concentration of medicinal mixture in subtaneous space, are placed. Depending on level of electric signal automatic control of operational mode of electronic portable doser "НДЛ" - 3, adapted for use in ophthalmology, is carried out automatically.
EFFECT: ensuring rational spending of medications during introduction of medicinal substances by me4ans of doser into subtaneous space.
1 dwg, 1 ex
SUBSTANCE: clinical dental health parameters following the endodontic treatment (Cl parameter) expressed in the quantitative equivalent according to table 3, are recorded. The X-ray periapical tissue health parameters following the endodontic treatment (Rtissue parameter) expressed in the quantitative equivalent according to table 4, are recorded.The X-ray root filling health parameters following the endodontic treatment (Rfilling parameter) expressed in the quantitative equivalent according to table 5, are recorded. In questionable cases, the recording procedure involves a higher rate of the estimation scale, and for multirooted teeth - the highest rate specified; each following root filling health parameter and its assessment criterion is secondary from the previous one depending on a degree of risk of potential post-endodontic complications and arranged in the ascending order, thereby characterising an increase of a therapeutic defect rate, except for the first assessment criteria of each of the parameters of a quantitative aspect of the X-ray filling health with 1 point assigned to describe the ideal clinical outcome for the given parameter. A complex index of the endodontic treatment expressed in points is calculated by formula: CIET = Cl+Rtissue+ΣRfilling, wherein CIET is the complex index of the endodontic treatment; Cl is the quantitative characteristics of the clinical dental health following the endodontic treatment; Rtissue is the quantitative characteristics of the X-ray periapical tissue health following the endodontic treatment; ΣRfilling is a total score derived in accordance with the criteria of the quantitative characteristics of the X-ray root filling health following the endodontic treatment. The clinical outcome is analysed on a basis of theoretical evaluation of numerical ranges of accepted values of the complex index of the endodontic treatment enabling to specify the therapeutic approach to the patient. The complex index less than 12 points testifies to adequate leak resistance of the root filling; pathological changes in the periapical tissues are absent; the tooth does not need to be treated; the prediction is considered to be favourable. If the range is 13-19 points, the root filling occurs to seal the root canal inadequately; the risk of periapical complications is minimised; the 6-24-month case follow-up is recommended. The range of 20-37 points shows the unsatisfactory leak resistance of the root filling; the high probability of post-endodontic complications is stated; the recurrent endodontic manipulation is recommended; the prediction is open to question. If the index reaches 37 points and more, the surgical management is recommended.
EFFECT: by additional quantitative characteristics of the clinical and X-ray periapical tissue and root filling health, the method enables characterising the quality of the therapeutic outcomes in the nearest and remote period, and specifying the indications for a certain method of treating.
SUBSTANCE: invention refers to medicine, namely to dentistry, and can be used in diagnosing body sensitivity to dental materials. A challenge test involving a 2-hour contact of a sampling material and an oral mucosa is conducted. The state of the oral mucosa microvasculature is assessed by computed biomicroscopy. A diameter of a capillary arteriolar domain, a diameter of a capillary venular domain, a mean diameter of a capillary, a diameter of gathering venules, a functional capillary density are measured. If one of the relevant parameters tends to vary at a value, which is at least 1.5 times as much as a parameter variation error, a high sensitivity to the dental materials is diagnosed.
EFFECT: technique enables providing the more objective and reliable procedure applicable to diagnose the sensitivity by using the computed biomicroscopy for studying the tissue changes and selecting the best assessment criteria.
6 dwg, 2 tbl, 3 ex
SUBSTANCE: invention refers to medicine, namely to cardiology. A method involves estimating a compliance level on the basis of 20 test questions of the compliance rating scale applicable for the patients suffering hypertensive disease; each question has three selective answers coded from 1 to 3 points; the patient either fills in the scale independently, or ticks the answers to the questions being read out by the doctor. The result interpretation involves the total score for all the questions: 51-60 means a high compliance level; 41-50 shows a medium compliance level, whereas 40 points or less stand for a low compliance level.
EFFECT: estimating the compliance level and objectifying the results in points in the patients with hypertensive disease of the 1st-2nd stage, in arterial hypertension of the 1st-3rd degree by means of the specifically developed rating scale applicable to estimate the compliance in the patients suffering hypertensive disease.
2 tbl, 2 ex
SUBSTANCE: invention refers to medicine, functional diagnostics and can be used for preclinical, predoctoral examination, assessment of the functional state of body organs and systems, and pre-diagnosis. The method involves measuring electrical conductivity (EC) of 24 representing points of 12 symmetrical meridians, determining an arithmetic mean (AM) value of these measurements and specifying a corridor of permissible values for this patient, to which the derived values are compared in order to assess the functional state of the patient's body. That involves using the following criteria: a ratio of total ECs of Yin meridian points to total ECs of Yang meridian points, a ratio of total ECs of arm points to total ECs of leg points, a ratio of total ECs of left-side points to total ECs of right-side points. ECs are measured at voltages 5V, and/or 9V, and/or 12V. If the measurements are taken at 9V, the measured ECs are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); if the measurement process is performed at 12V, the measured values are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); and at 5V: I new=1 measured*Coeff, (III), wherein in (I), (II) and (III) respectively: I new is the re-calculated EC; I measured is the measured EC; Coeff is a correction coefficient taking into account a meridian conductivity heterogeneity. The re-calculated values are transformed into adjusted ones by formula: I adjusted=I new/I mean, wherein: I adjusted is the adjusted EC; I new is the non-adjusted re-calculated EC; I mean is the arithmetic mean value of all the 24 measurements. That is followed by delimiting an individual normal corridor for this patient depending on the preset diagnostic sensitivity S and a width of corridor of the permissible EC values Wpv. The Wpv represents a range of EC values measured in this patient, whereas the diagnostic sensitivity S is specified depending on selecting the patients with a certain disease. Delimiting the individual normal corridor for this patient is ensured by measuring intermediate coefficients for lower Kl and upper Ku corridor limits respectively: Kl=1-(1-S)*Wpv/2.1 and Ku=1+(1-Kl)*1.1. Lower L and upper U limits of the individual normal corridor are determined: L=Kl* I mean and U=Ku* I mean. That is followed by comparing I adjusted to the derived limits of the individual normal corridor.
EFFECT: method provides high accuracy of the individual diagnosis.
4 tbl, 2 ex
SUBSTANCE: senior guinea pigs are exposed to optical light generated by light emitting diodes or fluorescent tubes at a colour temperature of 4,500 K within the wavelength region of 360-460 nm for various time distances. The exposure is assessed by functional activity indices of neutrophilic granulocytes and a mononuclear cell count.
EFFECT: using the method requires no expensive equipment, critical chemicals; it is of a particular importance for evaluating the biological safety of new artificial light sources embedded into a light-colour medium; it provides expanded information on biological effects of optical light.
SUBSTANCE: method involves specifying the patient's age in years, measuring a left atrium diameter in millimetres, assessing the anti-arrhythmic therapy provided and determining a degree of aortic and mitral incompetence. The produced values are used to calculate a risk (R) of recurrent atrial fibrillation following a radiofrequency ablation procedure by original formula. If the derived value R is more than 0.5, the development of recurrent atrial fibrillation is predicted to follow the radiofrequency ablation procedure; the value R of 0.5 or less shows no risk of recurrent atrial fibrillation following the radiofrequency ablation procedure.
EFFECT: higher prediction accuracy.
SUBSTANCE: invention relates to medical equipment, namely to equipment for visualisation of physiological data. Method of monitoring physiological parameters contains stages at which physiological parameters are measured periodically or aperiodically by at least one electronic sensor, with each measured value of physiological parameter having corresponding medical expiry date, determined and continuously visualised are: the last measured value of each measured physiological parameter and its designation, medical expiry date for each measured value of physiological parameter, which represents preliminary specified maximal time, during which value of physiological parameter is visualised, remaining medical term to expiry date of each measured value of physiological parameter for inquired time moment is determined, for each measured physiological parameter with non-zero remaining time period before expiry date determined and visualised on display are: the last measured value of physiological parameter, its designation and indication of remaining medical time period before expiry date in form of indicating the number of days, hours, minutes or seconds, during which reading is visualised, or indication of amount of time before visualisation of the following reading, with removal of reading from display in real time after preliminary configured medical term before expiry date finishes, absence of image is replaced with symbol, showing absence of current reading. Method is realised with application of machine-readable carrier, containing programme, recorded on it, and device for visualisation of data values and designations of patient's physiological parameters, which contains electronic sensors for periodical of aperiodical measurement of values of physiological parameters, processor, programmed for determination of the last measured physiological parameter and display device control.
EFFECT: application of invention makes it possible to increase rapidity of determination of data remoteness of the screen.
8 cl, 13 dwg
SUBSTANCE: "orthopaedic index" is calculated as a sum of three values. The first value is derived by conducting densitometry, and points are assigned according to its findings: 1 point for norm, 2 points for osteopenia, 3 points for osteoporosis, and 4 points for severe osteoporosis. The second value is derived by means of Charlson comorbidity index; 0-2 points according to the Charlson comorbidity index scale correspond to 1 point of the second value; 3 points of the Charlson comorbidity index scale are 2 points of the second value; 4 points of the Charlson comorbidity index scale show 3 points of the second value, while 5 points and more of the Charlson comorbidity index scale correspond to 4 points of the second value. The third value is determined by assessing the quality of life as per the scales SF-36; 0-200 points according to the scales SF-36 correspond to 4 points of the third value; 201-400 points of the scale SF-36 show 3 points of the third value; 401-600 points of the scales SF-36 provide 2 points of the third value, and 601-800 points correspond to 1 point of the third value. Total score is deriving by summing up the three values to determine "the orthopaedic index": I - 1-3 points, II - 4-6 points, III - 7-9 points, IV - 10-12 points. The form of treatment is defined: the patients with index I have the endoprosthesis replacement with endoprostheses with a shortened leg of the femoral component, the greater diameter of the head (36 mm or more); the patients with index II have the endoprosthesis replacement with cementless anchored total endoprostheses; the patients with index III have the total hip replacement with cemented endoprostheses; the patients with index IV have the endoprosthesis replacement with cemented anchored bipolar endoprostheses.
EFFECT: through assessing the available factors influencing the postoperative period, prosthesis anchoring in its bed, potential endoprosthesis rejection, functional effect and potential aggravation of comorbidities, the method can improve functional outcomes, reduce the risk of endoprosthesis loosening and the risk of recurrent operations.
SUBSTANCE: invention relates to devices for medical monitoring. The method contains stages at which: a packet (7) of data about a patient is transmitted from a device (10) for patient monitoring to the central server (12); a message (72) with acknowledgement (ACK), transmitted by the central server (12) in response to receiving by the central server (10) of the transmitted packet (70) of data about the patient, with a message with acknowledgement containing a time stamp, provided from the central server (12) clock (46), indicating the time and date, when the central server (12) received the packet (70) of the patient's data; the message time stamp (72) with ACK is compared with the current time of the clock (28) of the patient monitoring device (10); and if the difference between the current time of the clock (28) of the patient monitoring device (10) and the time stamp (74) with ACK is larger than the first preliminarily determined time, the clock (28) is synchronised in accordance with the time and date in the time stamp (74) in the message (72) with ACK.
EFFECT: provision of control of the time synchronisation interface.
13 cl, 5 dwg
SUBSTANCE: non-invasive examination of vessels is performed by means of a probe, installed on the skin surface in the projection of a vessel, by a method of optic coherent (OC) tomography, tomograms, obtained without compression test and OC tomograms under conditions of the compression test by the displacement of tissues by the probe by 1 mm towards the visualised vessel, are analysed. Compressibility of the vessel, tissues and formations and uniformity of the vessel configuration change under compression are estimated on the images. If a non-uniform and/or incomplete compressibility and a non-uniformity of the vessel configuration change are detected, microangiopathy is identified.
EFFECT: method ensures the high accuracy and objectivity of non-invasive diagnostics of the condition of microvasculature, in particular, the presence of intra-vascular formations, including differential diagnostics of vasculopathy due to the identification of particular criteria for the determination of pathological changes.
5 dwg, 4 ex
SUBSTANCE: method involves carrying out ultrasonic scanning examination of subclavian artery over its whole extent in physiological arm position with arterial blood pressure being measured in the middle one third of the arm. Next, when applying compression tests, blood circulation parameters variations are recorded in distal segment of the subclavian artery with arterial blood pressure being concurrently measured. Three degrees of superior thorax aperture syndrome severity are diagnosed depending on reduction of linear blood circulation velocity and arterial blood pressure compared to their initial values. Mild one takes place when linear blood circulation velocity reduction reaches 40% and arterial blood pressure 20% of initial level, moderate one when linear blood circulation velocity reduction reaches 70% and arterial blood pressure 50% and heavy one when linear blood circulation velocity reduction is greater than 70% of initial level and arterial blood pressure is greater than 50% to the extent of no blood circulation manifestation being observed in the subclavian artery.
EFFECT: high accuracy of diagnosis.
FIELD: medicine; medical engineering.
SUBSTANCE: method involves collecting information and storing it in single database or several databases representing parameter values of significance to enable one to carry out the procedures on his/her own, and operations for processing the mentioned single database or several databases to show alternative variants for making selection among two or more actions and values corresponding to each of two or more actions. Device has means for making calculations, required for implementing the method, and computer system and machine-readable carrier having program written on it and capable of implementing the method corresponding to the invention, on computer.
EFFECT: wider range of means accessible to end user.
69 cl, 8 dwg, 1 tbl
SUBSTANCE: method involves measuring intraocular pressure. Static computer-assisted perimetry method is used in a way that luminous spot serves as test object. The spot acts upon eye in various vision field points with threshold brightness and then in growing sequence. Eye retina light-sensitivity is measured in vision field points under study. The number of points is set with patient examination program. Total light-sensitivity is measured in decibels. Medicamentous reduction of intraocular pressure is achieved with 0.5% Ocupress solution introduced as drops twice with 5-6 min long interval. The intraocular pressure being reduced at least by 4 mm of mercury column, repeated static perimetry examination is carried out. Total light-sensitivity being increased less than by 50 dB, individual initial intraocular pressure tolerance conclusion is drawn. Total light-sensitivity being increased by 50 dB or more, individual initial intraocular pressure intolerance conclusion is drawn.
EFFECT: enhanced effectiveness in determining intraocular pressure tolerance/intolerance.