Oral care products, including zinc oxide and trimethylglycine

FIELD: pharmacology.

SUBSTANCE: group of inventions refers to oral care compositions, consisting of a mixture of zinc oxide and trimethylglycine (TMG), where the TMG is included into the composition in the form of hydrohalogenide, and zinc oxide and TMG form soluble complexes, selected from zinc-TMG-hydrohalogenide complexes, zinc-hydrohalogenide complexes and mixtures, where the hydrohalogenide is selected from hydrofluoride, hydrochloride and hydrobromide, as well as to a method for tooth enamel erosion treatment or mitigation, biofilm and bacterial plaque reduction, gingivitis reduction, tooth decay and cavities formation reduction, dentin hypersensitivity reduction, including application of such composition to the teeth, zinc oxide application together with the TMG in the form of hydrohalogenide during oral care composition production.

EFFECT: creation of a complex, capable of yielding a solution which precipitates when diluted.

15 cl, 4 ex, 6 tbl

 



 

Same patents:

FIELD: electricity.

SUBSTANCE: invention relates to the electroluminescent device. The device contains hole injecting layer, hole transport layer, electronic block layer, active luminescent layer based on luminescent substance, hole-block layer, electronic transport layer, electronic injecting layer. As the luminescent substance it contains bis[2-(N-tosylamino)-benzylidene-2-aminopyridinato] of zinc (II) of formula I: .

EFFECT: electroluminescent device based on chelate complexes of zinc of azometin derivants 2-(N-tosylaminobenzaldehyde), emitting in yellow-green spectrum.

6 dwg, 1 tbl, 1 ex

FIELD: chemistry.

SUBSTANCE: invention relates to chemistry and chemical technology, namely to synthesis of modified silicagels, containing molecules of substituted phthalocyanines covalently bound with them, and their application for water photoremediation. Method of water photoremediation with application of radiation of visible range in presence of oxygen and heterogenic sensibiliser of general formula: , where R=H is either SPh; X is anion; n=4-8; M=Zn, AlL, GaL, SiLz; L=Cl, OH; M=1-4.

EFFECT: invention makes it possible to carry out efficient purification of water from bacteriological contamination.

2 cl, 3 tbl, 11 ex

FIELD: chemistry.

SUBSTANCE: invention relates to zinc complexes of 5-[2-hydroxy(tosylamino)benzylidene-amino]-2-(2-tosylaminophenyl)-1-alkylbenzimidazoles of general formula I , where R = alkyl C1-C6; X=O, ; .

EFFECT: compounds I exhibit luminescent properties and can be used as luminophores for producing organic light-emitting diodes emitting white and visible light.

18 ex

FIELD: chemistry.

SUBSTANCE: invention relates to novel metal chelates, namely to zinc and cadmium complexes of tetradentate azomethines of 2-tosylaminebenzaldehyde and dioxydiamines of formula I , where m=2-4, n=2-4, M=Zn, Cd.

EFFECT: metal-complex compounds I demonstrate photoluminiscent properties in the blue spectrum region and can be used as an electroluminescent layer in the creation of organic light-emitting diodes (OLED) of white and visible light.

4 cl, 5 ex

FIELD: chemistry.

SUBSTANCE: claimed is a silicon-zinc-containing glycerohydrogel, possessing a wound healing, regenerative and antibacterial activity, a composition of which corresponds to formula kSi(C3H7O3)4·ZnC3H6O3·xC3H8O3·yH2O, where 1≤k≤4, 7≤x≤26, 20≤y≤100, obtained by interaction of tetraglycerolate of silicon in excess of glycerol Si(C3H7O3)4·xC3H8O3, where 0,5≤x≤10, monoglycerolate of zinc in abundance of glycerol ZnC3H6O3·6C3H8O3 and water in molar ratio Si(C3H7O3)4:ZnC3H6O3:C3H8O3:H2O equal to (1÷4):1:(7÷26):(20÷100) at a temperature of 20-40°C and intensive mixing.

EFFECT: claimed silicon-zinc-containing glycerohydrogel possesses the wound healing, regenerative and antibacterial activity, is simple to obtain and convenient in application.

1 tbl, 6 ex

FIELD: chemistry.

SUBSTANCE: invention relates to novel compounds in a series of chelate complexes of zinc with azomethine derivatives, namely to bis[2-(N-tozylamino)benzyliden-4'-dimethylaminophenyliminato]zinc(II) of formula I Also claimed is electroluminescent device.

EFFECT: invention makes it possible to obtain compounds, demonstrating electroluminescent properties with high brightness.

2 cl, 3 dwg, 1 tbl, 2 ex

FIELD: chemistry.

SUBSTANCE: described are 15-crown-5- and dithia-18-crown-6-containig 2-methyl-9-styryl phenanthrolines of formula: where as optical sensors on cations of calcium, barium and lead. Claimed compounds are obtained by interaction of ligand of 15-crown-5 or dithia-18-crown-6-containing 2-methyl-9-styryl phenanthroline with zinc perchlorate in acetonitrile with irradiation with red light.

EFFECT: complexes possess properties of highly efficient fluorescent sensors on cations of calcium, barium and lead, which make it possible to visually determine metal cation.

2 cl, 2 tbl, 2 ex

FIELD: chemistry.

SUBSTANCE: invention relates to zinc complex of asymmetric ethylenediamine-N,N-dipropyonic acid dichloride of formula Also claimed is method of its obtaining. Complex can be applied for solution of problems, associated with the necessity to introduce Zn2+ in chelate form instead of its mineral salts, as well as to serve as initial product for synthesis of other chemical compounds of series of polydentate ligands, in particular asymmetric ethylenediamine-N,N-dipropyonic acid.

EFFECT: obtaining zinc complex of asymmetric ethylenediamine-N,N-dipropyonic acid dichloride.

4 cl, 4 dwg, 3 ex

FIELD: biotechnologies.

SUBSTANCE: invention refers to a compound having general formula (I),

where: m and n are independent integer numbers of 1 to 6; each of X1-X3 and Y1-Y3 is O; each of R1-R3 is independently chosen from a group consisting of hydrogen or alkyl; and R is O-(CH2)x-C(-O)NR'-(CH2)y-NHR'. Besides, x and y are independent integer numbers of 1 to 6; and R' is chosen from the group consisting of hydrogen and alkyl. In addition, an antibody containing an antigen recognition area, use of the compound, pharmaceutical composition, use of the antibody, method for MMP-2 or MMP-9 activity inhibition in a sample and a composition for determining MMP-2 or MMP-9 are proposed.

EFFECT: invention allows obtaining compounds that are able to inhibit MMP-2 or MMP-9 activity.

11 cl, 16 dwg, 4 tbl, 11 ex

FIELD: chemistry.

SUBSTANCE: invention relates to molecular complexes of zinc and cadmium bis(1-phenyl-3-methyl-4-formyl-5-pyrazolonate) with amino-derivatives of nitric heterocycles of general formula (I) (NH2-Het)n, where NH2-Het is 1-aminoisoquinoline, 3-aminoquinoline, 6-aminoquinoline, 5-amino-4,6-dimethylquinoline, 2-aminopyridine, 2-amino-5-bromopyridine, 3-amino-5-methylisoxazole, 2-amino-1-ethylbenzimidazole, M is Zn, Cd, n=1, 2.

EFFECT: molecular complexes of formula (I) exhibit luminescent properties in the blue region of the spectrum and can be used as phosphors for making organic light-emitting diodes of white and visible light.

14 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry, namely represents composition, which contains mixture of particles of hydrophobic silicon dioxide aerogel, which have specific area of surface per weight unit (Sw) in range from 500 to 1500 m2/g and size, expressed in form of volume mean diameter (D[0.5]), in range from 1 to 1500 mcm, and at least one first linear silicone oil, which has viscosity higher than 50 mm2/s, and at least second and third linear silicone oils, and each of them has viscosity lower than or equal 50 mm2/s.

EFFECT: mixture of particles of silicon dioxide aerogel and linear oils provides possibility of obtaining compositions, which provide comfort and smoothness of skin after application and have dullness and "soft focus"-adding properties.

23 cl, 8 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions refers to an antiseptic pharmaceutical composition applicable for oral hygiene and treatment of microbial oral diseases, to a method for producing and using it. The composition contains from 0.05 to 0.3 wt % of hydrogen peroxide or its equivalent amount in the form of carbamide peroxide, from 0.001 to 0.03 wt % of eugenol, from 0.001 to 0.01 wt % of camphor, from 0.001 to 0.5 wt % of a salt of zinc or other heavy metals, such as silver, mercury, copper or a mixture thereof; from 1 to 1.2 wt % of sodium fluoride; from 2% to 7 wt % of xylitol, from 0.002 to 0.05 wt % of cetylpyridinium chloride and excipients in an amount sufficient to reduce the composition to 100%. The composition possesses a wide spectrum of action. What is also presented is a method for producing the composition and using it for producing a therapeutic agent effective for odour elimination, suppression and relief of an oral inflammation, dental tartar inhibition; for treating oral diseases; for rinsing and treating orthodontic damages; for preventing oral diseases during orthodontic treatment after oral operations and in the patients using fixed and temporary dentures; for relieving, treating or preventing oral diseases in different categories of patients, such as the patients receiving radiation therapy or chemotherapy, hospital patients and terminally ill patients, patients suffering from eating disorders, endocrine, haematological, cardiovascular and psychosomatic disorders, and besides physically or mentally deprived patients, patients with genetic or inherited changes.

EFFECT: preparing the antiseptic pharmaceutical composition.

22 cl, 3 ex

FIELD: medicine.

SUBSTANCE: invention relates to field of cosmetology and describes method of stopping unwanted hair growth on different body parts, characterised by the fact that first mechanical removal of hair with root on selected part of skin is performed with further application on said zone with open follicle ostia of depilatory based on salts of thioglycolic acid, sodium, potassium and calcium hydroxides and following rubbing to provide penetration of depilatory into hair follicle.

EFFECT: invention provides possibility of simultaneous destruction of hair follicle with preparations, allowed in medicine and cosmetology.

FIELD: chemistry.

SUBSTANCE: invention relates to cosmetic industry and provides a composition for depositing on keratin surfaces, which contains composition particles in the form of fused agglomerates having a part containing at least one dye and a part containing at least one transparent and translucent thermoplastic material, where the composition particles contain, based on the weight of all of the powdered composition material, about 10 to 90 parts of the dye part and about 90 to 10 parts of the transparent and translucent thermoplastic material part, and a method of producing the powdered composition material.

EFFECT: invention enables to obtain cosmetic compositions which will have an improved outer appearance on the skin and fewer SKU.

23 cl, 10 tbl, 11 ex

FIELD: medicine.

SUBSTANCE: invention refers to dentistry, namely represents an encapsulated oral care composition and an oral care device. According to the invention, the composition contains: (a) a gelatine capsule; and (b) an oral care composition inside the capsule and containing: (i) a hydrophilic active ingredient, (ii) a hydrophobic structuring ingredient, and (iii) an oil carrier. The hydrophilic active ingredient preferentially represents cetylpyridinium chloride. The hydrophobic structuring ingredient preferentially represents gelated mineral oil.

EFFECT: developing the composition according to the invention solves the problem of cetylpyridinium chloride migration and fish-eye capsule defect.

9 cl, 1 ex, 1 tbl

FIELD: chemistry.

SUBSTANCE: claimed invention relates to cosmetic field, namely represents method of colouring or lightening of keratin fibres, which includes stage of mixing without preparation at the moment of application of two compositions (A) and (B) and application of said mixture on said fibres; with said mixture including, at least, 25% of fatty substances relative to the total weight of composition, obtained in mixing two compositions (A)+(B).

EFFECT: method by invention makes it possible to produce intensive and uniform colouring of keratin fibres, with method simultaneously being easy to realise, because mixture in form of oil-reach emulsion does not flow down, but remains on application place, as well as makes it possible to lighten keratin fibres.

19 cl, 3 tbl, 1 ex

Shower gel // 2555358

FIELD: cosmetology.

SUBSTANCE: shower gel comprises lauryl glucoside, sodium carboxylate and lauryl glucoside, coco glucoside, cocon amidopropylbetaine, guar-hydroxypropyltrionium chloride, coco glucoside and glyceryl oleate, ethyl alcohol, a fragrance component, sanguinitrine derived from small-fruited plumepoppy, citric acid and water. The components of the gel are in a certain ratio in wt %.

EFFECT: invention provides high washing and foam-generating capacity with soft action which does not disturb the lipid layer of the skin and has a disinfecting action, without destroying own microflora of human skin.

3 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to liposomal compositions for application in cosmetic industry, including i) from 0.001 to 1 wt % of cyclo-(Arg-Gly-Asp-DPhe-Acha) and/or its salt or solvate, ii) from 0.01 to 20 wt % of one or more lipids; iii) from 60 to 99.99 wt % of one or more physiologically acceptable solvents, as well as to method of their obtaining and application for care and preservation of general condition of skin or hare, for prevention or reduction of wrinkles.

EFFECT: claimed compositions demonstrate favourable properties: improved effectiveness, higher stability, reduced immunogenic reactions in comparison with known properties.

18 cl, 3 dwg, 29 tbl, 18 ex

FIELD: chemistry.

SUBSTANCE: present invention relates to cosmetology and hygiene and provides a foaming detergent composition which contains: a) surfactants consisting of decyl glucoside and coco glucoside, where the decyl glucoside is present in an amount by weight which is 1.8 to 2.2 times the weight of coco glucoside, and b) water, where the amount of decyl glucoside is 10 to 30 wt % of the composition, wherein the composition is free of anionic surfactants.

EFFECT: invention enables to produce a detergent composition having foaming properties in the absence of an anionic surfactant that are equally effective as with a composition with an anionic surfactant.

23 cl, 6 ex

FIELD: cosmetology.

SUBSTANCE: invention is the biological means for cleaning and restoration of skin, comprising pancreatic tissue of pigs or birds, 70% ethyl alcohol, fragrance component, and Ringer's solution, at that the components in the means are in a certain ratio, in wt %.

EFFECT: acceleration of the process of skin regeneration, expanding of range of means having cleaning and skin restoring action.

3 dwg, 1 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to pharmaceutical industry, namely represents composition, which contains mixture of particles of hydrophobic silicon dioxide aerogel, which have specific area of surface per weight unit (Sw) in range from 500 to 1500 m2/g and size, expressed in form of volume mean diameter (D[0.5]), in range from 1 to 1500 mcm, and at least one first linear silicone oil, which has viscosity higher than 50 mm2/s, and at least second and third linear silicone oils, and each of them has viscosity lower than or equal 50 mm2/s.

EFFECT: mixture of particles of silicon dioxide aerogel and linear oils provides possibility of obtaining compositions, which provide comfort and smoothness of skin after application and have dullness and "soft focus"-adding properties.

23 cl, 8 ex

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