Probe for spectral analysis of substances and its application method

FIELD: physics.

SUBSTANCE: invention relates to physics. It can be used for preparation and movement of samples to analyzing device during spectral analysis of materials and substances. Probe consists of loop-bent wire of refractory material with tip for condensation of vapors of analyte and condensate supply of analyte into atomizer, made by bending ends of wire with probe runners and fixed on electric contacts of bearing platform with guides and damper. For improvement of repairability, providing fast process of replacing samples of analyzed samples probe is placed on contact site made of dielectric plate with electric contacts and guide slot. To provide stability of movement direction of probe during injection into dosing hole of furnace-pulverizer bearing platform is movably fixed to guide equipped with damper. Method of using probe consisting in fact that probe is fixed on moving with three degrees of freedom, manipulator bar. In furnace-atomizer via dosing hole sample of analyzed substance is introduced, above dosing hole cold probe fastened in manipulator is secured. Test substance is atomized in furnace and vapors effusing through dosing hole of furnace-pulverizer are deposited on cold probe. Probe with condensate of sample is introduced into dosing hole of furnace-pulverizer at temperature of substance atomization, electric current is supplied to probe, probe is heated and condensate sample is atomized. Vapors of sample condensate are analyzed using spectral instrument and required information on sample is obtained.

EFFECT: technical result is high accuracy and reliability of results of spectral analysis of substances and materials, higher reliability and maintainability of analytical equipment, fast process of replacing samples of analyzed samples, high efficiency during analysis.

4 cl, 9 dwg

 



 

Same patents:

FIELD: medicine.

SUBSTANCE: invention relates to a method of preparing and analysis of a multitude of cell suspensions, which includes, at least, the following successive stages, at which: (a) multitude of vials are loaded on a receiving site, with each vial containing a cell suspension, intended for analysis; (b) multitude of analytical reservoirs are loaded on the receiving site; and (c) cell suspension is sampled from a vial and introduced into an analytical reservoir, with stage (c) being repeated for each vial to be analysed; (d) samples are returned to the suspension; (e) relevant cells are selected by means of differential decantation; (f) volume, obtained as a result of the differential decantation is sucked in by means of pipette means, with the volume containing the sample, intended for analysis. The method is characterised by the following: stage (c) of sampling the cell suspension from the vial and its introduction into the analytical reservoir contains, at least, a stage of destructing cell clusters by means of pipette dosing means, with stage (f) of volume injection including the stage of "micromixing", which consists in sucking up the volume of the cell suspension immediately above the bottom of the decantation vial cone with the further pumping of a part of the sampled volume virtually in the same place. The invention also relates to a device.

EFFECT: claimed method is reliable, reproductive and fast and makes it possible to completely automate the preparation and analysis of cytological suspensions.

23 cl, 7 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and can be used for fecal sample automatic analysis. The fecal sample automatic analyser comprises an automatic controller, a sample container, a thinning device, an agitating and mixing device, an analysing device, a suction and cleaning device piped to the analysing device. The analysing device comprises a physical analysis unit and a chemical analysis unit. The suction and cleaning device comprises the sample suction needle, a thinner receiving unit and a peristaltic sample suction pump connected between the sample suction needle and the thinner receiving unit. The analysing device is connected between the sample suction needle and the peristaltic sample suction pump; when the sample suction needle is inserted into the sample container, and the peristaltic sample suction pump is positively rotated, the sample suction needle sucks the samples in from the sample container and supplies the fecal samples to the analysing device. The peristaltic sample suction pump is configured for reverse rotation and suction of the thinner from the thinner receiving unit for cleaning the analysing device and connection pipes after an analysis procedure.

EFFECT: invention provides reducing environment and laboratory contamination in the process of analysis, as well as higher performance.

15 cl, 6 dwg

FIELD: instrumentation.

SUBSTANCE: invention relates to instrumentation, in particular, to medical instrumentation. The device is a quadrupole magnet unit (1, 2, 3, 4) to provide for different gradient of the magnetic field on the sensor surface at the bottom of a unit, for example, a cartridge or a chamber, for the placement of a liquid sample in the biosensor in order to control the sample particles. Also, under the sensor surface a detector for particles accumulated on and/or near the sensor surface is installed, for example, an optic detector based on frustrated total internal reflection (FTIR).

EFFECT: improved measurement.

14 cl, 14 dwg

FIELD: testing equipment.

SUBSTANCE: immune monitoring test element includes a base element, at least one test column, containing a tested material, and a cover, such as an adhesive-attached cover from foil, covering the upper part of at least one test column. The cover includes a weakened part deformed inside directly above each test column, in which each weakened part deformed inside is formed by means of local pre-stressing of the specified part, but not to the point of cover piercing, in order to provide for cover piercing by means of an aspirating/distributing element, such as a dosing tip, providing for access to the test column content, without spraying of the test element test column content to adjacent test columns.

EFFECT: element improvement.

6 cl, 13 dwg

FIELD: chemistry.

SUBSTANCE: device for feeding samples into an analysis device has: first and second sample feeding channels, each having a section for loading and inputting samples, a tube for holding samples and a control valve; a position switching valve for successive connection of said first and second channels with the device; a channel for feeding cleaning liquid into said first and second channels; a sample input channel which is linked to said first channel or said second channel through the position switching valve; and a valve for selecting washing liquid which is meant for selecting washing liquid or system liquid for feeding into said first and second channels, such that the cleaning liquid and the system liquid successively flow on the first and second channels. The group of inventions also relates to a sample analysis method according to which samples are fed through one channel while cleaning the other channel.

EFFECT: group of inventions provides high rate of analysing multiple samples over a short period of time, high rate of washing the system with cleaning liquid.

28 cl, 6 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment, namely to devices for analysis of live organism gases. Spectrometer contains mass-analyser, interface of transcutant gas with input surface, input diaphragm in it and system of electrodes, contact transmission line for switching electrodes to generators of electric signals, canal of gas mixture transportation to mass-analyser. To region between input diaphragm and transcutant gas interface electrodes via gate-regulator of inhaled gas switched is canal of gas mixture transportation, connected with device for collection of exhaled gas. In input diaphragm of transcurant gas interface installed is gas gate-regulator of transcutant gas with mechanism for regulation of incoming gas flow.

EFFECT: application of invention makes it possible to realise fast multifunctional diagnostics of live organism simultaneously in exhaled and transcutant gases in real time mode.

1 dwg

FIELD: physics.

SUBSTANCE: device for capturing an image of a specimen in a specimen analysis device which includes an image capturing unit with a lens assembly with a fixed focal plane and a specimen holder, has a first block of magnets and a second block of magnets. The specimen holder is also made with possibility of embedding the specimen analysis device and with possibility of moving relative the lens assembly into a first position in which the first and second blocks of magnets lie at such relative positions that their magnetic interaction is possible. The specimen holder is made with possibility of moving from the first position to a second position during magnetic interaction of the first block of magnets and the second block of magnets. The image capturing unit is made with possibility of capturing the image of the specimen through the lens assembly when the specimen holder is in the second position. The method involves positioning the specimen analysis device in the specimen holder which has the first block of magnets, moving the said specimen holder relative the lens assembly with a fixed focal plane of the image capturing unit into the first position, where the first and second blocks of magnets are mutually arranged at such a short distance that they interact magnetically. The specimen holder is then moved from the first position to the second position through magnetic interaction between the first block of magnets and the second block of magnets, and the image of the specimen is captured through the lens assembly when the specimen holder is in the second position.

EFFECT: more efficient specimen image capturing, reduced device wearing.

16 cl, 5 dwg

FIELD: physics.

SUBSTANCE: group of inventions refers to a way and the device for automatic loading of tests of liquid chromatography. The way of automatic loading of test includes installation of a removable tip on a sampler with use of the automatic manipulator for a liquid. Thus the sampler forms a part of the automatic manipulator for a liquid. Then sampler moving by the automatic manipulator for a liquid is carried out in a loading position near to the test. Test loading in a removable tip is carried out with use of the automatic manipulator for a liquid. After that the sampler is moved by the automatic manipulator for a liquid in an introduction position near the port for tests introduction. Then insertion of the removable tip is carried out in the internal channel of the port for tests introduction, and the internal channel has a ring shoulder so the removable tip densely fits to the ring shoulder, and test introduction from a removable tip in the internal channel of the port for tests introduction. Thus the port for tests introduction is executed with an inlet opening of a port for an insert of the removable tip installed on a sampler of the automatic manipulator for a liquid. The port has the internal channel going from an inlet port opening, and the basis of the port executed as a part of the internal channel. The automatic manipulator for a liquid contains the device of sampler movement, a sampler installed on a console of the device of sampler movement, a syringe pump, connected with a sampler when operating, the control unit, connected with the syringe pump when operating to call aspiration of a test through the sampler, and a port for test introduction. Thus the introduction system contains the automatic manipulator for a liquid, the introduction valve and the junction circuit for the liquid medium, connecting the basis of the port for test introduction with the introduction valve.

EFFECT: decrease of the analysis time and decrease of cost of test processing.

22 cl, 9 dwg

FIELD: medicine.

SUBSTANCE: invention concerns the device and the method for automatic research of blood samples. The device for automatic research of blood samples contains a technological position (I) of sampling on which blood gets from the collection (40) by means of an intake, a measuring technological position (II) on which the taken away blood is referred through the aperture (26, 99) located in a measuring part (9, 90) diaphragms (30, 98), thus the measuring part (9, 90) is bridged to an intake, and a reception technological position (III) on which the measuring parts executed in the form of disposable parts (9, 90 are given) and are bridged to an intake. Besides the device for automatic research of blood samples contains the device for intake moving between sampling position (I), measuring position (II) and reception position (III). The intake has a needle part (15) which is executed with possibility of bond with (III) measuring part (90) given on a reception position, or includes a needle part (15) and a head part (46) which is executed with possibility of bond with (III) measuring part given on a reception position (9). On the sampling position (I) blood is entered into a needle part (15), and on a measuring position (II) blood through a head part (46) moves to a measuring part (9). The valve (10) is provided to establish alternate bond with the needle part (15) or with the head part (45). The method for automatic research of blood samples is characterised by that for intake moving the sampling device to the sampling position (I) by means of the first drive (4). The second drive (11) is put in action on a sampling position (I) for lowering of a keeping part (13) and a needle part (15). After immersing of a needle part (15) in blood containing in the collection (40) put in action the third drive (51) reception tanks (50) so that through a needle part (15), a tubular part (16) and the pipeline (14) blood is soaked up in the reception tank (50), and other valve (18) establishes bond between the pipeline (14) and the reception tank (50). Further the lever (3) is move to a reception position (III) by means of actuating of the first drive (4). Thus to the collecting device (7) for extraction of a measuring part (9; 90) is lower of the keeping part (13) moved earlier upwards by means of the second drive (11) by means of actuating of the second drive (11) so, that a measuring part (9; 90) it is tightly bridged to a head part (46) or with a needle part (15). After reception of the measuring part (9) the second drive (11) is put in action for moving of the keeping part (13) and for extraction of a measuring part (9; 90) from the collecting device (7). The lever (3) by means of the first drive (4) is moved to a measuring position (II). And the reception tank (50) is put in action by means of the third drive (51) so that blood constantly proceeds through the aperture (26) of the measuring parts (9; 90) also leaves this part through letting out blood area (31).

EFFECT: simplifying of the device at simultaneous maintenance of more economic researches.

37 cl, 4 dwg

FIELD: medicine.

SUBSTANCE: according to this method front-end interface is applied with acceptance surface and acceptance diaphragm, pressed to zone on human or animal body, furnished with vacuum-processed channel to deliver gaseous mixture to analyser in the capacity of which mass spectrometer is used. By means of electric field within second interface gaseous mixture is ionised, ions are drift within delivery channel. Particle flux received by analyser is tested with mass spectrometric structural analysis. Received mess spectrum is interpreted to conclude referring to analysis results.

EFFECT: reduced misrepresentation of transcoetaneous gas mixture composition for analysis.

1 dwg

FIELD: investigating or analyzing materials.

SUBSTANCE: device comprises sampling nozzle made of a hollow pipe, automatic control means, and filters. The inlet section of the sampling nozzle receives the calibration washer with fixed flow section. Downstream of the outlet section of the sampling nozzle are stop valve, cyclonic chamber, and bubbling chamber connected in series and to the gas pipeline. The bubbling chamber is filled with the anticoagulation fluid and has a free space. The space is connected with the fine filter through the control valve and calibrating washer. The flow section of the calibrating washer is smaller that that of the calibrating washer. The inner side of the sampling nozzle is made of a sublimating material throughout the length of at least 10 diameters of the flow section of the calibrating washer. The gas pipeline between the stop valve and bubbling chamber receives the system for pressurizing with the neutral gas.

EFFECT: enhanced reliability of sampling.

1 cl, 1 dwg

FIELD: measuring equipment engineering.

SUBSTANCE: device for taking samples by means of dropper with its washing includes at least two pumping blocks of different volume, rods of which are driven to reciprocal movement by means of common mechanized drive. Working chamber of each of these pumping blocks is connected to contour, containing serially positioned channel, opening into vessel, containing a resource of washing liquid RL, two serially positioned electromagnetic valves EV1, EV2 and pipe TS connected to means for taking samples by means of dropper AP, while working chamber of greater size is connected to portion of contour, providing connection between two electromagnetic valves EV1, EV2 while another working chamber is connected to portion of contour, positioned between second electromagnetic valve EV2 and means for taking samples by means of dropper.

EFFECT: simplified construction.

10 cl, 7 dwg

FIELD: chemical industry.

SUBSTANCE: device for conducting chemical reactions has sealing for conducting chemical reaction in reaction vessel. Sealing has permeable self-sealing diaphragm which closes hole of reaction vessel through which hole the agents are introduced into reaction vessel or are removed from it, and plunger made for reversing movement between specified position where there is access to diaphragm to penetrate through it, and position which provides tight contact with diaphragm. Plunger effectively resists to external deflection of diaphragm which deflection is caused by increase in internal pressure in reaction vessel. Plunger keeps diaphragm at the state of sealing at the area of penetration. The sealing is used for method of conducting chemical reaction in reaction vessel which can be achieved through self-sealing diaphragm that closes hole of reaction vessel. Method is based upon following operations: penetration through diaphragm by means of penetrating dozer for introduction/removal agents into/from reaction vessel to form tongue in the diaphragm; removal of penetrating dozer which results to deviation of tongue back to close area of penetration; application of controlled counter-pressure to external side of diaphragm by means of movable plunger to prevent diaphragm from deflecting back which deflection is caused by increase in internal pressure in reaction vessel, to prevent leakage or evaporation of agents through area of penetration. Automated system for conducting chemical reactions has the device described before as well as logic control circuits and operator interface module for checking and evaluating conductance of chemical reactions. Matter can be introduced/removed into or from the vessel many times. Pressure between introduction/removal of matter into vessel can be increased by means of pressure-resistant sealing.

EFFECT: improved reliability; improved efficiency.

16 cl, 4 dwg

FIELD: automatic treatment of biological fluids of patient as urine, blood serum, plasma, spinal fluid et cetera.

SUBSTANCE: method is used for preventing random repeat usage of agents containing inside container used before. Container for agents has at least one edge wall; container is placed into analyzer. Non-used containers are provided with mark element having weakened bridge connected with at least one edge wall. Bridge is subject to shift by means of measuring prod made for warning about the shift under the condition when non-used container is housed into analyzer. Container also has signal analyzer for measuring values within preset ranges for non-used containers. In case the length of prod's path and shift force do not belong to the ranges mentioned, then second usage can be claimed. Design of multi-department container is also given.

EFFECT: improved precision.

16 cl, 10 dwg

FIELD: precise automatic sampling device with washing of pipette.

SUBSTANCE: in accordance to invention device contains at least two pumping devices of cylinder-piston type, which are driven by one common electric motor MP. Pumping chamber of each one of pumping devices is connected to contour, containing, serially: channel exiting into reservoir RL of washing liquid, three serial electromagnetic valve (EV1, EV2, EV3) and a section of contour, which connects second electromagnetic valve (EV2) to pipette device AP. Bigger pumping chamber is connected to section of contour which provides connection between two electromagnetic valves (EV1, EV2), while second pumping chamber is connected to aforementioned section of contour by means of connector, while aforementioned section of contour contains electromagnetic valve EV3 positioned between connector and pipette device.

EFFECT: increased reliability and precision of device operation.

1 cl, 8 dwg

FIELD: biological danger detection systems.

SUBSTANCE: automatic system and device can be used for detection of those biologically active agents as Siberian plague, in sending. Completely automated system for detection of biologically dangerous agents has device for identification of biological agent, collecting unit for taking aerosol sample of particles of spayed biological agent onto site of inspection and device for concentrating aerosols. Device for concentrating aerosols is intended for getting liquid sample from aerosol sample. Automated system has automatic jet unit fro storing and transporting portion of liquid sample into cartridge-type container, automatic mechanic system for shifting container from area of accumulation to point of filling of liquid of jet device and then to device for identification of biological agent. Device for identification of biological agent has biological agent identifier on base of polymer chain reaction. System has control device to provide general automatic control, for controlling device at specified part of inspection and for sending results of testing to preset point, which testing is performed by device for identification of biological agent. Invention provides method of detection of biological agent point source. System for detection of biological agent has high sensitivity when applying polymer chain reaction, which method is capable of detecting of at least 200 spores for one milliliter of sample to prevent missing of mortal danger, in particular, of Siberian plague in devices, which transport and treat sending.

EFFECT: improved reliability; improved sensitivity.

38 cl, 14 dwg

FIELD: medicine.

SUBSTANCE: according to this method front-end interface is applied with acceptance surface and acceptance diaphragm, pressed to zone on human or animal body, furnished with vacuum-processed channel to deliver gaseous mixture to analyser in the capacity of which mass spectrometer is used. By means of electric field within second interface gaseous mixture is ionised, ions are drift within delivery channel. Particle flux received by analyser is tested with mass spectrometric structural analysis. Received mess spectrum is interpreted to conclude referring to analysis results.

EFFECT: reduced misrepresentation of transcoetaneous gas mixture composition for analysis.

1 dwg

FIELD: medicine.

SUBSTANCE: invention concerns the device and the method for automatic research of blood samples. The device for automatic research of blood samples contains a technological position (I) of sampling on which blood gets from the collection (40) by means of an intake, a measuring technological position (II) on which the taken away blood is referred through the aperture (26, 99) located in a measuring part (9, 90) diaphragms (30, 98), thus the measuring part (9, 90) is bridged to an intake, and a reception technological position (III) on which the measuring parts executed in the form of disposable parts (9, 90 are given) and are bridged to an intake. Besides the device for automatic research of blood samples contains the device for intake moving between sampling position (I), measuring position (II) and reception position (III). The intake has a needle part (15) which is executed with possibility of bond with (III) measuring part (90) given on a reception position, or includes a needle part (15) and a head part (46) which is executed with possibility of bond with (III) measuring part given on a reception position (9). On the sampling position (I) blood is entered into a needle part (15), and on a measuring position (II) blood through a head part (46) moves to a measuring part (9). The valve (10) is provided to establish alternate bond with the needle part (15) or with the head part (45). The method for automatic research of blood samples is characterised by that for intake moving the sampling device to the sampling position (I) by means of the first drive (4). The second drive (11) is put in action on a sampling position (I) for lowering of a keeping part (13) and a needle part (15). After immersing of a needle part (15) in blood containing in the collection (40) put in action the third drive (51) reception tanks (50) so that through a needle part (15), a tubular part (16) and the pipeline (14) blood is soaked up in the reception tank (50), and other valve (18) establishes bond between the pipeline (14) and the reception tank (50). Further the lever (3) is move to a reception position (III) by means of actuating of the first drive (4). Thus to the collecting device (7) for extraction of a measuring part (9; 90) is lower of the keeping part (13) moved earlier upwards by means of the second drive (11) by means of actuating of the second drive (11) so, that a measuring part (9; 90) it is tightly bridged to a head part (46) or with a needle part (15). After reception of the measuring part (9) the second drive (11) is put in action for moving of the keeping part (13) and for extraction of a measuring part (9; 90) from the collecting device (7). The lever (3) by means of the first drive (4) is moved to a measuring position (II). And the reception tank (50) is put in action by means of the third drive (51) so that blood constantly proceeds through the aperture (26) of the measuring parts (9; 90) also leaves this part through letting out blood area (31).

EFFECT: simplifying of the device at simultaneous maintenance of more economic researches.

37 cl, 4 dwg

FIELD: physics.

SUBSTANCE: group of inventions refers to a way and the device for automatic loading of tests of liquid chromatography. The way of automatic loading of test includes installation of a removable tip on a sampler with use of the automatic manipulator for a liquid. Thus the sampler forms a part of the automatic manipulator for a liquid. Then sampler moving by the automatic manipulator for a liquid is carried out in a loading position near to the test. Test loading in a removable tip is carried out with use of the automatic manipulator for a liquid. After that the sampler is moved by the automatic manipulator for a liquid in an introduction position near the port for tests introduction. Then insertion of the removable tip is carried out in the internal channel of the port for tests introduction, and the internal channel has a ring shoulder so the removable tip densely fits to the ring shoulder, and test introduction from a removable tip in the internal channel of the port for tests introduction. Thus the port for tests introduction is executed with an inlet opening of a port for an insert of the removable tip installed on a sampler of the automatic manipulator for a liquid. The port has the internal channel going from an inlet port opening, and the basis of the port executed as a part of the internal channel. The automatic manipulator for a liquid contains the device of sampler movement, a sampler installed on a console of the device of sampler movement, a syringe pump, connected with a sampler when operating, the control unit, connected with the syringe pump when operating to call aspiration of a test through the sampler, and a port for test introduction. Thus the introduction system contains the automatic manipulator for a liquid, the introduction valve and the junction circuit for the liquid medium, connecting the basis of the port for test introduction with the introduction valve.

EFFECT: decrease of the analysis time and decrease of cost of test processing.

22 cl, 9 dwg

FIELD: physics.

SUBSTANCE: device for capturing an image of a specimen in a specimen analysis device which includes an image capturing unit with a lens assembly with a fixed focal plane and a specimen holder, has a first block of magnets and a second block of magnets. The specimen holder is also made with possibility of embedding the specimen analysis device and with possibility of moving relative the lens assembly into a first position in which the first and second blocks of magnets lie at such relative positions that their magnetic interaction is possible. The specimen holder is made with possibility of moving from the first position to a second position during magnetic interaction of the first block of magnets and the second block of magnets. The image capturing unit is made with possibility of capturing the image of the specimen through the lens assembly when the specimen holder is in the second position. The method involves positioning the specimen analysis device in the specimen holder which has the first block of magnets, moving the said specimen holder relative the lens assembly with a fixed focal plane of the image capturing unit into the first position, where the first and second blocks of magnets are mutually arranged at such a short distance that they interact magnetically. The specimen holder is then moved from the first position to the second position through magnetic interaction between the first block of magnets and the second block of magnets, and the image of the specimen is captured through the lens assembly when the specimen holder is in the second position.

EFFECT: more efficient specimen image capturing, reduced device wearing.

16 cl, 5 dwg

Up!