Method for simulating bone-reconstructive surgeries in treating new growths of jaw bone in childhood
SUBSTANCE: invention relates to medicine, namely, to maxillofacial surgery and orthodontics. For simulating bone-reconstructive surgeries in treating new growths of jaw bone in childhood is carried out KT examination of skull with subsequent reconstruction in 3D programs and create a three-dimensional model of skull, identify new growth, calculate basic parametric data of neoplasms and virtually it is removed in the resulting model, then virtually fill a defect or flaw, then prototyping reconstructive models of jaws or endoprosthesis using a 3D printer. For virtual removal of neoplasm is performed a 3D cephalometry, on the received 3D model of skull manually placed cephalometric marks at maximum increase of screen resolution, using simultaneously different projections, perspective, right, left, top, front and by varying the transparency of the image from 0 to 100 %, determined 48 cephalometric parameters against which is carried out a virtual replacement of defect or flaw zone with subsequent virtual correction of jaw bones during the staged orthodontic-surgical treatment.
EFFECT: method allows to simulate and predict the staged surgical-orthodontic and orthopaedic treatment in a child until its growth, as well as reduce a probability of unplanned step operations.
1 cl, 21 dwg, 4 tbl, 1 ex
SUBSTANCE: water-soluble iodine-containing contrast substance is introduced to a patient intravenously, computer tomography is carried out, after which the point measurement of densitometric indices is carried out before and after obstruction in each contrasted coronary artery (CA). If the density of the contrasted CA lumen before and after obstruction at least in one of them differs by more than 80 HU, the degree of injury is considered to be haemodynamically significant, and surgical treatment is indicated to the patient.
EFFECT: method makes it possible to estimate the functional significance of CA stenosis in a single step and with high accuracy due to the integrated CT estimation of the coronary blood flow in the entire CA.
SUBSTANCE: invention relates to computed tomographic scanner. Proposed device comprises: radiation source (2) and detector (6) to generate detection magnitudes depending on radiation conical beam (4). Unit (12) generates weights for combination of image voxels and detection magnitudes for weighing said detection magnitudes. Beam generator generates the radiation conical beam (4) so that for at least for a portion of magnitudes dispersion inversion of appropriate magnitude positively correlates with the mean values of weights of appropriate combinations of voxels. The latter correspond to appropriate magnitude of detection.
EFFECT: higher quality of reconstructed images.
13 cl, 14 dwg
SUBSTANCE: invention refers to medicine, oncology and can be used for two-phase scanning in multispiral computed tomography while following up abdominal and retroperitoneal oncologic cases. A non-ionic contrast medium is administered in a general dose. The dose is administered by two successive boluses in ratio 2:1. A time interval of the two administrations is specified so as to provide forming a combined image of arterial and venous contrast enhancement phases within one scanning procedure.
EFFECT: method provides reducing a radiation dose considerably - by 50% as compared to the traditional two-phase scanning by only performing one scanning procedure.
3 dwg, 2 ex
FIELD: physics, computer engineering.
SUBSTANCE: present invention relates to generation of X-rays, and specifically to a method and a system for simulating dose reduction during X-ray imaging. A method of simulating dose reduction when collecting X-ray system data comprises a step of providing first X-ray information containing first noise, wherein the first X-ray information is collected with a first dose adjustment parameter, a step of providing a second dose adjustment parameter, a step of determining noise difference to obtain simulated second X-ray information collected with a second dose adjustment parameter, and a step of incorporating the noise difference into the first X-ray information to obtain simulated second X-ray information containing second noise. The noise difference is a local noise difference which depends on the local intensity distribution of the first X-ray information.
EFFECT: use of the invention enables to optimise the signal-to-noise ratio without deterioration of image quality.
13 cl, 3 dwg
SUBSTANCE: invention relates to medical equipment, namely to means of obtaining movement images, for instance, y means of positron-emission tomography. Method of detecting movement in the process of obtaining images by means of medical system contains stages at which subject's image is obtained in order to form data of obtaining images, which include time-of-flight data, time-of-flight data are controlled in the process of obtaining images, time-of-flight data are analysed to detect movement. Method of estimating respiratory movement in data of obtaining images contains stages at which subject's electrocardiogram is additionally obtained in the process of obtaining images and used to gating image data in order to form cardiosynchronised data, after which cardiosynchronised data are divided into time subintervals in order to obtain respiration-synchronised heart images, centre of activity is determined in respiration-synchronised heart images and centres of activity in different respiration-synchronised heart images are compared in order to form vectors of respiratory movement. In the second version of evaluation method electrocardiogram is used to divide data of obtaining images into cardiac cycles, centre of activity in cardiac cycles is determined and centres of activity in different cardiac cycles are compared in order to form vectors of respiratory movement.
EFFECT: application of invention makes it possible to reduce probability of errors in synchronisation of examination with respiratory movements.
15 cl, 9 dwg
SUBSTANCE: performed are: introduction of a radio-opaque preparation in the blood stream and multispiral computer-tomographic MSCT - arteriography with single-step return multispiral computer-tomographic MSCT-portography. Selective catheterisation of the celiac trunk (CT) and superior mesenteric superior mesenteric artery (SMA) is carried out simultaneously, the first portion of the contrast preparation is introduced into SMA in a volume of 25.0-35.0 ml at a rate of 1-2 ml/sec under a pressure of 200 PSI. After 13-17 s the second portion of the contrast preparation is introduced into CT and SMA in a volume of 12.0-18.0 ml at a rate of 3-5 ml/sec under a pressure of 200 PSI. Scanning is realised in one phase 2-4 sec after the introduction of the second portion of the contrast preparation, direction of scanning is cranio-caudal or caudo-cranial, parameters of scanning are the following: thickness of the cut - 1.5 mm, speed of the tube rotation - 0.5 sec, 100-140 kV (kilovolt), 250-350 mA (milliamper). Tumour invasion of vessels is verified by the condition of vascular wall contours on the obtained images.
EFFECT: reliable determination of the vessel invasion by the tumour at a pre-operative stage, with good visualisation of both the external, and internal contours of the vascular wall simultaneously contrasted arterial and venous vessels, minimisation of the radiation exposure of the organism with the maximal self-descriptiveness, extension of the arsenal of diagnostics means in patients with tumours of the biliopancreatoduodenal zone.
SUBSTANCE: method involves the nasoenteric administration of 99mTc-pertechnetate into a small intestine at 1.0-14 MBq/kg diluted with normal saline to an amount of 20 ml. That is immediately followed by a dynamic scintigraphy by means of two-detector rotation gamma-chamber for 60 minutes with a gamma-chamber detection mounted above a projection of the intestine and liver. Following the examination results enables calculated an absorption coefficient of a radiopharmaceutical agent (K); thereafter the scintigraphy is continued in the mode of "The Whole Body", which provides a basis to determine a percentage of the radiopharmaceutical agent (A) absorbed from an intestinal lumen. If the absorption coefficient is less than 3 and the absorption is less than 50% from the administered radiopharmaceutical agent, the small intestinal malabsorption is stated. K is described by the scintigram forming the sharpest image of the liver and having an area of interest 100 pxls to be marked within a liver, which is followed by constructing an activity/time curve. K is calculated as a slope of the curve to a horizontal axis with using the first 4 minutes of the linear rise of the curve by formula: K=(y2-y1)/(t2-t1)×60, wherein K is the absorption coefficient, t1 and t2 are time distances, seconds; y1 is a pulse count within the time distance t1, y2 is a pulse count within the time distance t2. To calculate A, an area including the whole patient's body and an area covering the visualised enteric loops are marked on the scintigram. The calculation follows the formula: A=(n(b)-n(e))/n(e)×100%, wherein n(b) is the total pulse count recorded within the whole body; n(e) is the total pulse count recorded within the small intestine.
EFFECT: method provides the high information value of the examination ensured by the complex analysis of the enteric function parameters in the early postoperative period.
3 cl, 3 dwg, 1 ex
SUBSTANCE: computed tomography (CT) apparatus comprises a scanning tunnel, a fixed X-ray source placed around the scanning tunnel and having a plurality of focal spots which emit radiation and a plurality of fixed detector modules placed around the scanning tunnel opposite the X-ray source. One part of the modules from the plurality of detector modules is located in a first direction and the second part of the modules from the plurality of detector modules is located in a second direction, and the arrangement of said parts of the detector modules is L-shaped. The first direction forms a straight line by connecting the centre points of the radiation beam receiving surfaces of one part of the detector modules. The second direction forms a second straight line by connecting centre points of the radiation beam receiving surfaces of the other part of the detector modules, which cross at a certain point when viewed in a plane which crosses the scanning tunnel. The radiation beam receiving surfaces of one part of the detector modules are inclined relative to the first direction and face the X-ray source, and the radiation beam receiving surfaces of the other part of the detector modules are inclined relative to the second direction and face the X-ray source.
EFFECT: fixed CT apparatus without a gantry according to the invention has small dimensions and high data identification accuracy.
18 cl, 3 dwg
SUBSTANCE: neurovisualisation examination of brain is carried out, Cirs comorbidity index and Kaplan-Feinstein comorbidity index are determined, cochleovestibular syndrome, eye-moving impairments, type of diabetes mellitus are identified. Value of discriminate function (D) is calculated. If D value is higher than zero, diagnosed are consequences of ischemic brain stroke (IBS) with hyperhomocysteinemia (HH), if D is lower than zero, consequences of IBS without HH are diagnosed.
EFFECT: method makes it possible to increase reliability of diagnostics of IBS consequences, which is achieved due to complex analysis of said parameters.
SUBSTANCE: invention relates to medical equipment, namely to means for obtaining diagnostic information. Device contains unit for obtaining data of part of person's anatomical structure, planning unit, which specifies sequence of scanning stages with reference to spatial position and orientation of approximate anatomical structure, user's interface for setting parameters of image formation at selected stage of scanning. User's interface reflects for each stage of selected sequence of scanning stages preliminarily specified parameters of scanning, related to approximate anatomical structure, and is configured with possibility of user's selection of real parameters of image formation with reference to three-dimensional volume of real anatomical structure. Method of obtaining diagnostic information consists in device application.
EFFECT: device application makes it possible to facilitate planning for users.
12 cl, 2 dwg
SUBSTANCE: invention relates to medicine. System for determining location of relief reference point on orthopaedic implant contains device, made with possibility of processing in autoclave. Said device contains case, field generator for generation of electromagnetic field, first electromagnetic sensor for placing at specified distance from relief reference point and element, connected with case with possibility of detachment. Case is made with possibility of processing in autoclave. Said field generator contains multitude of elements, generating magnetic field and located inside case. Said device is made with possibility of functioning after sterilisation in autoclave. First electromagnetic sensor for placement at specified distance from relief reference point generates sensor readings in response to generated electromagnetic field. Said element determines longitudinal axis, representing one axis of generated electromagnetic field. System is made with possibility of using one axis of generated electromagnetic field for determination of element position relative to relief reference point.
EFFECT: invention provides possibility of easy sterilisation or processing in autoclave for re-use.
15 cl, 62 dwg
SUBSTANCE: group of inventions refers to medicine, namely to a device and a method for magnetic particle exposure and/or detection in a field of vision. For zooming-out and still accessing a patient while forming an image, the device comprises two or more transmission coil sets with neighbouring coil sets overlapped partially. The transmission coil set comprises: a pair of concentric selection field coils for generating a magnetic selection field having such space distribution of its magnetic intensity that the first subzone having low magnetic intensity and the second subzone having higher magnetic intensity are generated in the field of vision; and at least one pair of travelling field coils for repositioning spatially the two subzones in the field of vision by the travelling magnetic field in such a way as to change magnetic particle excitation locally. The above at least one pair of travelling field coils is parallel to the above pair of selection field coils and is formed by the two neighbouring turns.
EFFECT: zooming-out and still accessing the patient.
13 cl, 11 dwg
SUBSTANCE: invention refers to medicine, functional diagnostics and can be used for preclinical, predoctoral examination, assessment of the functional state of body organs and systems, and pre-diagnosis. The method involves measuring electrical conductivity (EC) of 24 representing points of 12 symmetrical meridians, determining an arithmetic mean (AM) value of these measurements and specifying a corridor of permissible values for this patient, to which the derived values are compared in order to assess the functional state of the patient's body. That involves using the following criteria: a ratio of total ECs of Yin meridian points to total ECs of Yang meridian points, a ratio of total ECs of arm points to total ECs of leg points, a ratio of total ECs of left-side points to total ECs of right-side points. ECs are measured at voltages 5V, and/or 9V, and/or 12V. If the measurements are taken at 9V, the measured ECs are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); if the measurement process is performed at 12V, the measured values are re-calculated by formula: I new=9/(29/I measured-0.1)*Coeff, (I); and at 5V: I new=1 measured*Coeff, (III), wherein in (I), (II) and (III) respectively: I new is the re-calculated EC; I measured is the measured EC; Coeff is a correction coefficient taking into account a meridian conductivity heterogeneity. The re-calculated values are transformed into adjusted ones by formula: I adjusted=I new/I mean, wherein: I adjusted is the adjusted EC; I new is the non-adjusted re-calculated EC; I mean is the arithmetic mean value of all the 24 measurements. That is followed by delimiting an individual normal corridor for this patient depending on the preset diagnostic sensitivity S and a width of corridor of the permissible EC values Wpv. The Wpv represents a range of EC values measured in this patient, whereas the diagnostic sensitivity S is specified depending on selecting the patients with a certain disease. Delimiting the individual normal corridor for this patient is ensured by measuring intermediate coefficients for lower Kl and upper Ku corridor limits respectively: Kl=1-(1-S)*Wpv/2.1 and Ku=1+(1-Kl)*1.1. Lower L and upper U limits of the individual normal corridor are determined: L=Kl* I mean and U=Ku* I mean. That is followed by comparing I adjusted to the derived limits of the individual normal corridor.
EFFECT: method provides high accuracy of the individual diagnosis.
4 tbl, 2 ex
SUBSTANCE: invention relates to medicine, electric puncture screening-diagnostics and can be used in different fields of medicine, psychology, sport, where monitoring of person's state for long-term time period with operative correction of their indices is required. Electric puncture impact on person's corporal biologically active points (BAP) by means of hardware-software complex with application of positive and negative polarities, measurement of electric skin resistance (ESR) in BAP and further analysis of results by mutual location of ESP profiles are performed. Additionally carried out is spectral diagnostics, including analysis of spectral Fourier series of frequency changes, when measured point is adapted to provoking impact of measuring current, with further formation by means of computer programme of frequency therapeutic module, consisting of patient's functional frequencies, isolated from their frequency spectrum in case when they do not correspond to their standard indices. Frequency therapeutic module is aimed at diagnosed points to carry out operative correction of functional state of organs and systems. Analysis of spectrum of frequency characteristics is realised in range 0.015-100 Hz with discreteness 0.015. Frequency therapeutic modules are formed at specified time interval of 1 minute and longer depending on patient's state. Operation of diagnostics and correction of functional state of organs and systems is realised by cycle with period (1…N) depending on patient's state.
EFFECT: method provides increase of diagnostics accuracy due to increased quantity of diagnostic characteristics and optimal reduction of noise component, with reduction of quantity of diagnosed points, which provides reduction of diagnostics time, increase of long-term monitoring efficiency due to possibility of specifying diagnostic cycles.
5 cl, 5 dwg
SUBSTANCE: invention relates to medical equipment, namely to devices for magnetic resonance. Device contains electric device or component, which includes printed circuit board, and radiofrequency shield, made with possibility of shielding electric device or component, with radiofrequency shield including earth bus of printed circuit board. Device is placed in opening of magnetic-resonance scanner in radiofrequency (B1) field. Earth bus of printed circuit board includes electro-conductive sheet or layer, which has openings, suppressing vibration of earth bus, induced due to changing in time gradient of magnetic field. Magnetic-resonance system contains magnetic-resonance scanner, including basic magnet, winding for creation of magnetic field gradient and one or more radiofrequency coils for production of radiofrequency (B1) field in studied area. Device is placed in opening of magnetic-resonance scanner.
EFFECT: application of invention makes it possible to improve efficiency of MR-compatible electric device work due to reduction of vibration, caused by radiofrequency field.
14 cl, 11 dwg
SUBSTANCE: invention can be used for diagnosing the Dupuytren's contracture (DC) of fingers. High-resolution MR imaging covering the palmar aponeurosis of interest is used to record the time of nuclear magnetic relaxation T2 * on hydrogen nuclei of isotropic signal component of the CH2 lipid group. The derived coefficient T2 * is inserted into the discriminate analysis equation: DC=-3.37+0.24·T2 *. CD is diagnosed if the equation value is <0.313. If the derived equation value is ≥0.313, the diagnosis of DC is not confirmed.
EFFECT: technique provides the non-invasive one-hour verification of the DC diagnosis at the pre-clinical stage with no imaged signs of the contracture.
1 dwg, 3 ex
SUBSTANCE: invention is intended for visualising the structure of the atherosclerotic plaque in brachiocephalic arteries in the diagnostics of a risk of ischemic impairment of the cerebral blood flow (IICBF) in patients with extensive atherosclerosis and can be used in radiodiagnostics, neurology and vascular surgery. Contrasting T1-weighed spin-echo MRI of the neck and head area is carried out with thin cuts in the axial plane, 1-3 mm thick, with the compulsory inclusion of the area of the carotid arteries bifurcation, with the introduction of a contrast agent - paramagnet in a dose of 2 mM/10 kg of body weight. The examination is carried out twice: initially and 5-8 min after the introduction of the contrast agent-paramagnetic, an image amplification index (AI) is determined for the area of atherosclerotic plaque as the ratio of intensity of T1-weighed image with contrasting by means of the paramagnetic (IT1WIcontrast) to the intensity of T1-weighed image on the initial (IT1WIinitial) non-contrasting examination AI= IT1WIcontrast/IT1WIinitial. In case ofthe plaque presence in the area of the internal carotid artery or in the place of its deviation from the general carotid artery and AI value in the area of the said plaque larger than 1.22, risk of the acute IICBF development is predicted.
EFFECT: method provides high self-descriptiveness of MRI method of examination with the visualisation of the structure of the atherosclerotic plaque, identification of the presence of neoangiogenesis, which reliably increase the risk of rupture and ischemic affection of the brain.
8 dwg, 1 ex, 2 tbl
SUBSTANCE: invention is intended for visualisation of regions of local myocardium dystrophy in evaluating efficiency of radiofrequency ablation (RFA) of renal arteries in patients with resistant arterial hypertension. Before and after RFA T1-weighed spin-echo ECG-synchronised MRI of heart is conducted by cuts on short axis of left ventricle 7-8 mm thick 8-15 min after introduction of contrast paramagnetic substance in dose 2 ml of 0.5 M solution per 10 kg of body weight. Volume of contrast inclusion into myocardium and in case of its reduction by value less than 1 cm3 in comparison with value of said index before RFA, RFA is evaluated as effective.
EFFECT: method ensures clear visualisation of myocardium injury areas, their extension and localisation.
5 dwg, 1 tbl, 2 ex
SUBSTANCE: aponeurosis boundary is identified according to the findings of the geometry analysis of layered hand MR-scans in axial and coronary projections on 1H cores in the mode of proton density measurement. The palmar aponeurosis criterion is its thickness of more than 1×10-3m.
EFFECT: method provides the non-invasive pre-operative identification in vivo of the aponeurosis boundaries for no more than 40 minutes and makes it possible to form 2D-images according to MRT findings with the topographic-anatomic verification of the palmar aponeurosis spreading.
5 dwg, 3 ex
SUBSTANCE: device for correction of sleep characteristics contains sensor for registration of electrodermal activity EDA, connected with unit of analysis and extraction of signals of skin-galvanic responses SGR, generator of stimulating electric pulses, on-skin electrodes and control unit. Device is made in form of monoblock with possibility of fastening on user's palm. Monoblocks case has front and back side, and fastening elements. Three electrodes, placed with possibility of galvanic connection with skin of user's hand palm, are located on back part. Measuring electrode is connected to input of sensor for EDA registration, with stimulating electrode being connected to output of generator of electric pulses, with the third one being common neutral electrode of galvanic circuits of said sensor and generator. Units of analysis and extraction of SGR signals and control unit are made on base of microprocessor with possibility of periodical control of current condition of galvanic contact of electrodes with skin, cyclic measuring of SGR intensity and supply of stimulating electric pulses in pauses between SGR measuring, and provide three modes of functionality: sleeping mode - in absence of galvanic contact of electrodes with skin; mode of EDA registration - in presence of galvanic contact of electrodes with skin, including extraction of SGR pulses and counting their quantity N for given time interval and comparison with threshold value; mode of stimulation - if quantity N of SGR pulses exceeds threshold value, including periodical supply of electric pulses to stimulating electrodes during specified time interval.
EFFECT: invention application makes it possible to extend arsenal of technical means for correction of patient's physical condition during sleep and further wakefulness, increase index of slow-wave sleep stage, power of delta-waves and therefore deepen sleep sensation, phases of fast eye motions, and increase sleep quality in general.
9 cl, 10 dwg
SUBSTANCE: method involves carrying out urological examination for determining hydrodynamic resistance of ureter calculated from formula Z=8Lμ/(πR4), where Z is the hydrodynamic resistance of ureter, L is the ureter length, R is the ureter radius, μ is the urine viscosity. Angle α at which the ureter enters the urinary bladder is determined from formula cosα = 8l1μ/(ZπR4), where l1 is the perpendicular drawn from the upper edge of the ureter to the its exit projection line, μ is the urine viscosity, Z is the hydrodynamic resistance of ureter, R is the ureter radius. Vesicoureteral reflux recidivation is predicted when the angle of α+90° is less than 120°.
EFFECT: enhanced effectiveness in reducing the number of recidivation cases.
2 dwg, 1 tbl