Biologically active additive for making cosmetics
SUBSTANCE: invention refers to cosmetic industry and represents a biologically active additive for making cosmetic compositions, containing modified dextrane and cosmetically acceptable carrier, differing by the fact, that dekstranal with molecular weight 20–75 kDa is used as modified dextran, wherein ingredients of additive are taken in certain proportions, wt%.
EFFECT: invention provides anti-inflammatory and moisturizing effect with simultaneous improvement of elastometry and profilometry of skin.
3 cl, 4 ex, 4 tbl
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical industry, namely represents composition, which contains mixture of particles of hydrophobic silicon dioxide aerogel, which have specific area of surface per weight unit (Sw) in range from 500 to 1500 m2/g and size, expressed in form of volume mean diameter (D[0.5]), in range from 1 to 1500 mcm, and at least one first linear silicone oil, which has viscosity higher than 50 mm2/s, and at least second and third linear silicone oils, and each of them has viscosity lower than or equal 50 mm2/s.
EFFECT: mixture of particles of silicon dioxide aerogel and linear oils provides possibility of obtaining compositions, which provide comfort and smoothness of skin after application and have dullness and "soft focus"-adding properties.
23 cl, 8 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: group of inventions refers to an antiseptic pharmaceutical composition applicable for oral hygiene and treatment of microbial oral diseases, to a method for producing and using it. The composition contains from 0.05 to 0.3 wt % of hydrogen peroxide or its equivalent amount in the form of carbamide peroxide, from 0.001 to 0.03 wt % of eugenol, from 0.001 to 0.01 wt % of camphor, from 0.001 to 0.5 wt % of a salt of zinc or other heavy metals, such as silver, mercury, copper or a mixture thereof; from 1 to 1.2 wt % of sodium fluoride; from 2% to 7 wt % of xylitol, from 0.002 to 0.05 wt % of cetylpyridinium chloride and excipients in an amount sufficient to reduce the composition to 100%. The composition possesses a wide spectrum of action. What is also presented is a method for producing the composition and using it for producing a therapeutic agent effective for odour elimination, suppression and relief of an oral inflammation, dental tartar inhibition; for treating oral diseases; for rinsing and treating orthodontic damages; for preventing oral diseases during orthodontic treatment after oral operations and in the patients using fixed and temporary dentures; for relieving, treating or preventing oral diseases in different categories of patients, such as the patients receiving radiation therapy or chemotherapy, hospital patients and terminally ill patients, patients suffering from eating disorders, endocrine, haematological, cardiovascular and psychosomatic disorders, and besides physically or mentally deprived patients, patients with genetic or inherited changes.
EFFECT: preparing the antiseptic pharmaceutical composition.
22 cl, 3 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to pharmaceutical industry, namely to a method for preparing a medicinal product possessing choleretic activity. The medicinal product possessing choleretic activity and prepared by extracting an elevated part of Lomatogonium carinthiacum in 96% ethanol twice at room temperature, them in 40% ethanol with an extractant added in an amount equal to a discharged one, twice; the filtered aqueous-alcoholic extracts are combined; the extraction cake is extracted in purified water; the aqueous extract is filtered; the aqueous residues of the aqueous-alcoholic extracts are combined with the aqueous extract, concentrated, dried in a vacuum drying cabinet to produce the dry extract in the certain environment.
EFFECT: medicinal product prepared as described above possesses the evident choleretic activity.
11 tbl, 3 ex
SUBSTANCE: group of inventions relates to medicine and is intended for oral cavity care. Compositions contain non-dialysable material of cranberry extract, in which non-dialysable material of cranberry extract is present in quantity, effective for inhibiting co-aggregation of oral cavity bacteria and/or inhibiting bacterial growth.
EFFECT: group of inventions makes it possible to increase efficiency of oral cavity care due to inhibition of bacterial growth and co-aggregation of bacteria.
15 cl, 5 tbl, 4 ex
FIELD: veterinary medicine.
SUBSTANCE: method comprises subcutaneous administration of antibiotic preparation enroxyl 5% at a dose of 0.1 ml/kg daily one time a day for 7 days and intramuscular administration of homeopathic preparation ovarinin at a dose of 1 ml/kg one time for 4 days, 4-fold.
EFFECT: use of the invention enables to increase the efficiency of treatment, to reduce treatment time and to restore reproductive function of dogs.
2 tbl, 1 ex
SUBSTANCE: black adler syrup having laxative action, characterised by the fact that it is produced by preparing black adler tea by boiling the raw material with purified water; the tea is further mixed with refined sugar; the mixture is heated until the sugar is dissolved completely and brought to boil twice with skimming as often as it may be required; the prepared syrup is filtered through gauze in the certain environment.
EFFECT: syrup is high in anthracene derivatives and possesses the pronounced laxative action.
2 dwg, 1 ex
SUBSTANCE: invention refers to medicine and cosmetology, namely to deep cosmetic products, and can be used for normalising physiological functions of skin and eliminating endogenous or exogenous defects. The invention represents a cosmetic product for fast skin repair containing superoxide dismutase, dexpanthenol, succinic acid, trolox and L-arginine. The product is applied on the skin for 20 minutes with using a material holding the agent and feeding it to the skin over the period of exposure.
EFFECT: cosmetic product enables extending the range of products for improving the skin state, reducing the risk of lower controllability of the effect, and a probability of allergic and inflammatory reactions.
3 cl, 10 ex
SUBSTANCE: using a polyphenolic complex produced by extracting milled ash berry in 40% ethanol, condensing the alcohol-water extract, adding 95% ethanol, centrifuging the residue, filtering and condensing the supernatant in the certain environment, as an agent possessing anti-inflammatory action.
EFFECT: polyphenolic complex possesses pronounced anti-inflammatory action.
1 dwg, 9 tbl, 7 ex
SUBSTANCE: group of inventions refers to veterinary science and is applicable for treating bovine mastitis. What is declared is a nosode for producing a preparation for treating bovine mastitis. That involves taking mastitis milk 1 ml with clinical signs of purulent-catarrhal mastitis, filling it 70° alcohol 9 ml to produce a homogenous solution; the produced solution is diluted to "Д6" with 70° alcohol. What is also declared is a preparation for treating bovine mastitis containing an aqueous-alcoholic solution of components. The components are Belladonna, Sulphur, Apis mellifica, Conium, Phytolacca, Silicea and above nosode in the following proportions, wt %: Belladonna - 5, Sulphur - 20, Apis mellifica - 20, Conium - 10, Phytolacca - 10, Silicea - 5, nosode - 15, aqueous-alcoholic solution up to 100%. What is also declared is a method of treating bovine mastitis involving the intracisternal administration of the preparation. The preparation is administered in a dose of 5-10 ml per 1 animal once a day.
EFFECT: declared group of inventions is highly effective in treating bovine mastitis.
3 cl, 5 tbl, 1 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to pharmaceutical composition, containing compound of formula or for prevention or treatment of diseases, associated with oxidative stress, selected from group, consisting of MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke episodes), MERRF syndrome (myoclonic epilepsy with ragged red fibres) or Kearns-Sayre syndrome, arrhythmia, cardioplegia or myocardium infarction. in formula (1) na stands for 1 or 2, Aa represents 5-membered heteroaryl or heterocycle, each of which has 2 heteroatoms, selected from N, O and S, Rla represents R5a-Xa-Ba-X′a-, Ba represents direct bond, Xa and X′a independently on each other represent direct bond or -OC(O)-, R5a represents hydrogen or 6-9-membered monocyclic or condensed cyclic heterocycle or heteroaryl, each of which has from 1 to 3 heteroatoms, selected from N, O and S, and is optionally substituted with oxo or C1-C6-alkyl, R2a represents -(CR8aR9a)pa-Ya-R7a , pa stands for number from 0 or 1, Ya represents direct bond or -O-, R7a represents hydrogen or phenyl, R3a, R8a, R9a, R10a represent hydrogen, R4a represents -(CH2)pa-Da-R10a-, Da represents C5-cycloalkyl or 6-membered heterocycle, which has 1 heteroatom, selected from N, S and O. Radical values for formula (2) are give in invention formula.
EFFECT: obtaining compositions for prevention or treatment of diseases, associated with oxidative stress.
19 dwg, 5 tbl, 3 ex
FIELD: medicine, oncology, amino acids.
SUBSTANCE: invention relates, in particular, to the development of an antitumor preparation based on natural substances. Invention relates to an amino acid preparation comprising at least one modified essential amino acid obtained by treatment of amino acid by ultraviolet radiation (UV) at wavelength 250-350 nm for 12-80 h at temperature 15-30oC or with ozone at temperature 15-25oC. The modified amino acid has no toxicity for health cells. Also, invention relates to a method for preparing such preparation. Invention provides the development of an antitumor preparation based on modified amino acids and expanded assortment of antitumor preparations being without cytotoxicity for normal cells.
EFFECT: valuable medicinal antitumor properties of preparation.
8 cl, 4 tbl, 2 dwg, 4 ex
FIELD: medicine, gastroenterology.
SUBSTANCE: after selecting all biliary portions one should introduce firstly a certain anolyte at the quantity of 100-150 ml at ORP = +700 - +1200 mV; pH = 6.0 - 7.3 for a patient through a sound, then one should introduce a certain catholyte at the quantity of 150-200 ml at ORP being -400 - -800 mV; pH = 8.5 - 9.5 into a free sound. The present innovation enables to decrease relapses in diseases of biliary canals at the background of restricted usage of chemotherapeutical preparations.
EFFECT: higher efficiency of curative sounding.
2 ex, 1 tbl
FIELD: organometal chemistry, stomatology.
SUBSTANCE: invention relates to titanium compounds of formula [TiF2L2] or containing group of formula [TiFxLy]z-, wherein x = 2, 4 or 5; y = 1 or 2; z = 1 or 2; L is group of formula II , wherein m = 1; n = 0, 1 or 2, in enantiomer, diastereomer forms, or mixture thereof, including racemates; as well as free bases or pharmaceutically acceptable salts. Composition containing claimed compounds for buccal application to prevent dental caries also is disclosed.
EFFECT: compounds with improved stability capable to form lacquer on dental surface.
14 cl, 1 ex
FIELD: cosmetology, food industry.
SUBSTANCE: the present innovation deals with compositions for cosmetic preparations, means for personal hygiene, purifying components, biocidal components, functional food and food additives. Due to these compositions one should introduce bioactive glass containing SiO2, CaO, P2O5 and Na2O, not obligatory, into the objects mentioned. Moreover, the present innovation deals with methods to obtain and apply the compositions mentioned. It enables to obtain cosmetic products capable to withstand bacterial infection.
EFFECT: higher efficiency.
134 cl, 19 ex, 5 tbl
FIELD: medical engineering.
SUBSTANCE: method involves acting in turn with ultrasonic and magnetic field with switch frequency of 10 to 160 Hz. Ultrasonic field intensity is set below cavitation threshold and ultrasonic oscillation frequency being equal to liquid acoustic relaxation frequency. Magnetic field induction being selected within the limits of 30-50 mTesla units.
EFFECT: enhanced effectiveness of liquid activation; reduced power consumption.
FIELD: medicine, infectious diseases.
SUBSTANCE: method involves administration of electroactivated aqueous solutions of salts with negative and positive redox-potential and definite pH value and with the concentration of active chlorine in the definite sequence and regimen. Invention promotes to arresting basic pathogenetic syndromes of disease due to normalization of metabolic processes in body and recovery of the normal microbiocenosis and by development of conditions promoting to using the own natural potential by human. Invention can be used for complex treatment of parasitic and infectious diseases.
EFFECT: improved method for treatment.
3 cl, 4 ex
FIELD: experimental medicine, immunology.
SUBSTANCE: invention relates to a method for immunization of intact animals with ram erythrocytes treated by alternating magnetic field 50 Hz and 25 mTl for 30 min. Method provides enhancement of induction of the primary immune response in experimental animals. Invention can be used for stimulation of immune response in experiment.
EFFECT: improved method for stimulating.
FIELD: medicine, stomatology.
SUBSTANCE: invention proposes an agent for prophylaxis and treatment of dental caries that comprises carrier and active substance wherein carrier is made as a bicomponent system consisting of rubber or rubber-like elastomer eliciting high residual deformation and spherical or approaching to spherical rubber particles or rubber-like polymer eliciting the residual deformation less 0.001% and showing deformation indices 10-25 kg/cm2 at relative elongation 0.1-0.25 and in the ratio of components in the carrier = (30:70)-(85:15) wt.-%, size of particles is 1.0-5.0 mm and wherein active substance involves active sources of fluorine, calcium and phosphate ions. Agent is made as plate, rod or block. Method for prophylaxis and treatment of caries involves chewing the indicated agent with strength providing release of active substance from carrier and maintaining the concentration of calcium and fluorine ions in saliva 10-4 - 10-5 M, respectively, for 5-15 min, not less. Agent and method show high effectiveness in treatment and prophylaxis of caries and comfortable using also.
EFFECT: improved, enhanced and valuable medicinal properties of agent and method.
3 cl, 2 tbl
FIELD: medicinal biotechnology, immunology.
SUBSTANCE: invention relates to producing medicinal biological preparations. Invention relates to a method for enhancing specific activity of immunoglobulins of class G. Method involves freezing immunoglobulin G-containing fractions to temperature from -20°C to -196°C and subjected for gamma-irradiation in doses 5-50 kGr with power of absorbed dose 60-110 Gr/min. method provides elevating the specific activity of immunoglobulin G, increasing titer, avidity and reducing anti-complementary activity.
EFFECT: improved method for elevating activity of antibodies.
3 tbl, 3 dwg, 4 ex
FIELD: medicine, stomatology.
SUBSTANCE: therapy suggested should be performed due to applying a thin layer of 0.1%-butyric estradiol solution followed by a 5-min-long ultrasound treatment of the target surface. The method provides complex therapy and prophylaxis of parodontium diseases due to local substitution hormonotherapy with estradiol-containing solution.
EFFECT: higher efficiency of therapy.