Device for manipulating objects using acoustic force field

FIELD: machine building.

SUBSTANCE: invention relates to device (1) intended for manipulating objects (O) located in channel (2) inside fluid medium (F), in particular, liquid. Device includes channel (2) passing along longitudinal axis (X), wherein channel (2) has cross section with width (L) measured along first transverse axis (Y), and thickness (e), measured along second transverse axis (Z), perpendicular to first one. Width (L) exceeds thickness (e) or equal to it and channel has first (3) and second (4) walls located along second transverse axis (Z). Device includes acoustic waves generator (10), generating acoustic waves in channel from at least one of said walls (3, 4), wherein said acoustic waves generator (10) operates at frequency f, different from channel (2) resonance frequency f0 along second transverse axis (Z). Result is formation of at least one objects layer (N) by means of acoustic focusing.

EFFECT: possibility of changing of objects focusing position inside channel, possibility of objects focusing on entire size of channel.

27 cl, 5 ex, 13 dwg



Same patents:

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine and can be used for blood analyte test. A system for biological fluid analysis comprises a pre-assembled member (14) receiving the biological fluid in a capillary gap (28), a test element (18), a handler (20) for generating the fluid connection between the pre-assembled member (14) and the test element (18), and a detection unit (22). The handler (20) places the test element (18) into contact with the biological fluid in the capillary gap (28); a fluid column remains on an indication surface of the test element (18). The fluid volume of the capillary gap (28) is determined so that the fluid column on the indicator surface over the period of a variation interval stays above a minimum height making more than 10mcm. The handler (20) is configured for physical separation of the test element (18) and the pre-assembled element (14) after the measurement. The group of invention refers to a method for the biological fluid analysis by means of the above system.

EFFECT: group of inventions provides higher accuracy and reproducibility of the analysis results.

14 cl, 4 dwg

FIELD: medicine.

SUBSTANCE: invention refers to a system and a method for blood value tracking. The system comprises: an access device for providing a related one percutaneous access to each patient's blood; sampling devices for blood sampling from each patient to prepare one blood sample in each specific case; one analytic device for analysing the blood sample; a calculation device configured for common availability for data arrays with blood values of various patients; a uniting device for setting an identification code in each specific case for identifying the patient and/or code of a time slot for specifying the time slot; and feeding devices for supplying a respective drug to a respective patient with each data array with drug parameters, including a unit dose, for the respective patient is transferred together with the identification code and/or code of the time slot as a common data array by wired or wireless devices from the calculation device to any of the respective feeding devices; one of the respective feeding devices feeds an amount of the respective drug in accordance with the common data array to the respective patient.

EFFECT: higher-accuracy dosage with continuous drug feed.

10 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to laboratory diagnostics. A method for designing a storage unit for analytical tools comprises: designing a first component of the storage unit of the analytical tools containing a number of receiving portions; designing a number of analytical aids coupled and directed in relation to each other by a retention element; introducing the analytical aids into the receiving portions with all the compartments loaded simultaneously; separating the analytical aids from the retention element; applying a chemical agent in the form of a continuous area of the chemical agent applied on a disruption-free carrier; the area of the chemical agent provides chemical agent regions for a number of sections. The group of inventions refers to the storage unit for analytical tools made according to the above method, and to the version of the above method.

EFFECT: group of the inventions provide designing the storage unit for analytical tools with cutting the production costs without loss of quality of the storage unit for analytical tools.

15 cl, 7 dwg

FIELD: process engineering.

SUBSTANCE: proposed process comprises the steps that follow. Coordinates of vehicle location and local concentrations of harmful gas components are monitored continuously along the boundary of sanitary-hygienic zone with the help of identical multisensory automatic gas analysers. The latter are displaced at diametrically opposite rings. Measured magnitudes are transmitted to central server equipped with appropriate software. Obtained magnitudes of radial distributions of local concentrations are compared with marginal values. Proceeding from the results of comparison, conclusion is made on air conditions at different points of analysed territory of emission sources.

EFFECT: lower costs, time saving, higher validity, fast evaluation of ecological situation.

2 cl

FIELD: medicine.

SUBSTANCE: group of inventions refers to laboratory diagnostics. A device for the automatic detection of an analyte in a body fluid sample comprises an array of addressed analysis units for carrying out a chemical reaction, which generates a distinguishable signal carrying the information concerning the presence or absence of the analyte; an array of addressed reagent units referring to the individual addressed reagent unit, corresponding to the individual addressed analysis unit, and wherein the individual reagent unit is configured to be calibrated by a reference signal in the respective individual analysis unit before the arrays are assembled on the device; the individual analysis unit comprises a quantitative analysis tip having an inner surface carrying the reagents fixed on the surface for the analyte detection. The group of inventions refers to an embodiment of the above device additionally comprising a sampling unit, as well as to sub-systems comprising the above devices, methods for analysing using the above devices, a method for assembling the above devices and a method for sampling plasma from the blood sample in these systems.

EFFECT: group of inventions provides the higher flexibility and reliability of the system, as well as prevents cross-contamination of the units of the device.

65 cl, 21 dwg, 3 tbl, 7 ex

FIELD: medicine.

SUBSTANCE: group of inventions relates to field of biology, in particular to immunological research, which is preferable method of testing biological products and in the process of which tray for samples is applied, in particular, in realisation of enzyme-linked immunosorbent assay - ELISA, or other procedures, associated with immune assay, applying nucleic acid probe, as well as in application for carrying out testing for presence of DNA- or RNA sequences. Tray contains one or more depressions for samples, with each depression for samples having base and one or more open through holes made in base. Each of open through holes has circle-shaped transverse section and is made cylindrical, with diameter smaller than diameter of reagent granule or microsphere introduced in it. Reagent granule or microsphere is held or fixed in said through hole bi means of interference fit or friction fit with formation of peripheral sealing, impermeable for flowing medium with respect to base wall, forming said through hole.

EFFECT: group of inventions provides increased efficiency and quality of research with simultaneous reduction of time consumption.

9 cl, 34 dwg

FIELD: oil and gas industry.

SUBSTANCE: quantitative estimation of hydrocarbon component content is identified against specific caloric efficiency on which value intensity of colour shades in the flame plume of fired gas mixture determined as per RGB colour model. When gas mixture cannot be fired with hydrocarbon components due to insufficient percentage of hydrocarbons, the known quantity of hydrocarbon gas sufficient for firing of the gas mixture. By adding measured portions of hydrocarbon gas with the known specific calorific efficiency intensity of colour shades in the flame enriched in the above method by hydrocarbon gas of the gas mixture. Against changes in colour shades of the flame both percentage of hydrocarbon components in the gas mixture and hydrocarbon content are identified when the initial gas mixture cannot be fired. Efficiency of associated gas enrichment is judged against comparison of hydrocarbon components content in associated gas before its delivery to the enrichment plant and at the plant output.

EFFECT: possibility of qualitative and quantitative identification of hydrocarbon components in associated gas, efficiency of associated gas enrichment.

2 cl, 1 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely laboratory diagnostics and can be used for performing thecluster analysis. The analysis procedure involves the stages as follows: a) providing a suspension of superparamagnetic particles in a liquid to be analysed with the superparamagnetic particles coated with a biologically active agent; b) enabling the particles forming particle clusters with analytes found in the liquid; c) using a rotating magnetic field (B) with an angular frequency ensuring the magnetic field rotation only of the clusters having a size smaller or equal to a pre-set size, and d) detecting the rotating clusters. What is also presented is a device for performing the cluster analysis.

EFFECT: group of inventions provides detecting the selectively activated clusters thereby increasing the analysis sensitivity.

9 cl, 8 dwg

FIELD: physics.

SUBSTANCE: invention provides a method of controlling excitation of marker particles in a biosensor, particularly a biosensor employing frustrated total internal reflection (FTIR). When applying a predefined excitation force to the marker particles and determining the effect of the applied excitation force in space or on the binding surface of the sensor cassette of the biosensor device, control with excitation force feedback is used.

EFFECT: providing a biosensor which is adapted to carry out the method according to the invention.

9 cl, 2 ex, 3 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to a system and a method for drug administration into a patient. The system comprises a movable drug container (5, 14); a device (3) for making the first identification element with the first patient, drug and/or treatment data to be attached to the drug container (5, 14); a reading device (6) for reading the first data from the first identification element (5a); a supply unit for supplying the drug to the patient from the container (5, 14) inserted into the supply unit (11). The reading device (6) is presented to read the second data included into the second patient's (9) identification element (10) and attached to the supply unit (11). A control unit (16) is provided in the supply unit (11) for supplying the first control signal (13) to activate a supply procedure to one of supply modules (12a-12e) of the supply unit (11), if the first and second data are matched. There are provided the second comparison unit (18) in the supply unit (11) for comparing the first drug data to the second drug data in a storage unit (19) of the supply unit (11), and a selection unit (21) for selecting the first and/or second drug data at least partially, if there is a mismatch of the first drug data, and the second drug data. What is disclosed is a method for drug supply.

EFFECT: inventions provide a safer drug supply to the greater number of patients.

7 cl, 3 dwg

FIELD: physics, acoustics.

SUBSTANCE: group of inventions relates to an apparatus for irradiating a sample with focused acoustic energy, a device which is part of said apparatus, a cartridge for said device and a method of irradiating a sample with focused acoustic energy. The apparatus comprises a device, a cartridge, a completely solid-state connector and a source for generating acoustic energy. The cartridge has a chamber for receiving a sample, and the completely solid-state connector provides a completely dry coupling of acoustic energy between the source and the cartridge. The device and the cartridge are adapted for inserting the cartridge containing a sample into the device and are separable, and the focused acoustic energy is focused high-intensity ultrasound. The device has a source for generating acoustic energy and the cartridge has a chamber for receiving a sample.

EFFECT: improved sample processing.

17 cl, 24 dwg

FIELD: physics.

SUBSTANCE: method includes placing liquid media and objects located in a medium inside a mechanical oscillatory channel system, having a nonlinear relationship between resonant oscillation frequency and amplitude, wherein the method includes maximum alignment of resonance curves of an ultrasonic vibration generator and the nonlinear resonance curve of the channel system itself by determining the nonlinear resonance curve of the channel system as the relationship between the amplitude of mechanical vibrations and frequency, determining the difference between the frequency of the generator and the resonant frequency of the channel system at the required amplitude of vibrations and, based on said difference, changing the resonant frequency of the channel system by changing the geometric dimensions of the sizes. If the difference in frequency exceeds about 1.5-2.0 times the width of the resonance curve of the generator, vibrations are generated at two or more different frequencies.

EFFECT: high efficiency of cavitational effect on a processed liquid medium and objects in the medium.

12 dwg, 1 tbl

FIELD: food industry.

SUBSTANCE: homogeneous milk product manufacture device consists of a mixing vessel with an appliance for dry milk components loading therein, a rotary disperser connected to the mixing vessel in the recirculation circuit via the recirculation pump, an inlet nozzle connected (via the doser pump) to a sonochemical reactor connected to the ultrasound generator. Additionally, the invention relates to a method for hydration of polar molecules of milk proteins amino acids in the homogeneous milk product preparation process performed in the homogeneous milk product manufacture device. According to the invention, into the mixing vessel one adds dry whole or defatted milk or dry milk whey or a dry milk protein concentrate and water preliminarily treated in the sonochemical reactor at mean amplitude of sound pressure no less than synperiodical cavitation mode amplitude; one spends 5…9 kilojoules of cavitation mode acoustic energy for treatment of 1 l of water.

EFFECT: invention allows to manufacture homogeneous milk products based on natural milk, buttermilk with addition of vegetal fats and dry whole or defatted milk or dry milk whey or a dry milk protein concentrate without excessive energy expenditure.

2 cl, 3 dwg

FIELD: aviation.

SUBSTANCE: invention represents the method to obtain the soluble concentrate from sideline products of reindeer antlers, comprising aqueous raw extraction, grounded up to the forced meat condition with particle size of 3-5 mm under the action of ultrasonic vibrations with frequency of 37 kHz with subsequent filtration and vacuum drying at temperature of 45°C and pressure of 0.9 atm, distinguished by the fact that the aqueous raw extraction is carried out at temperature of 35-36°C in the presence of pepsin ferment at its concentration in raw mixture: water of 0.5% during at least 3 hours, at ratio raw: water for tails 1:5, for male genital 1:4, for uteruses with embryos and amniotic fluid 1:2.

EFFECT: significant increase of final concentrate yield from sideline products of reindeer antlers.

3 ex, 2 tbl

FIELD: physics.

SUBSTANCE: method includes placing liquid media and objects located in a medium inside a mechanical oscillatory channel system, having a natural oscillation frequency, in which parametric resonances are excited or parametric excitation of self-oscillation is performed, setting as the cavitational processing efficiency criterion the oscillation amplitude of the channel system, determining optimum frequency of oscillation frequency of power exciters with experimentally predetermined natural and parametric oscillation frequencies.

EFFECT: shorter processing time, higher power of acoustic waves and higher efficiency of cavitational processing of liquid media and objects located in the media.

12 dwg

FIELD: technological processes.

SUBSTANCE: invention relates to devices for physical and chemical treatment by ultrasonic cavitation of molecular and colloid solutions, and also disperse systems, phases of which may include live forms, by initiation of sonochemical reactions in media of such solutions and cavitation erosion of their phases. A sonochemical reactor for treatment of liquids includes a working volume filled with liquid flowing through it and limited with the surface of the body, which belong to a single solid-state vibrating system, from metal by two emitting surfaces and a binding surface between them, at the same time the centre of mass of this system is the centre of its geometric symmetry, for which purpose emitting surfaces belong to acoustic waveguide transformers of identical shape, dimensions and mass, transmitting coherent cophased flat-elastic oscillations from both sides from sources into liquid at frequency of free elastic oscillations of this solid-state vibrating system from metal, into composition of which they are included, and binding length makes half of length of vibration wave in metal, from which it is made.

EFFECT: invention provides for increased acoustic capacity of a cavitation reactor and increased efficiency of liquid treatment in it due to reduced losses of energy of ultrasound exciting cavitation.

2 cl, 4 dwg, 1 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to field of chemical technology of energy-saturated materials, namely to methods of utilisation of formed wastes of production of defective and expired products, and is intended for laboratory methods of trinitrotoluene decomposition. Method of trinitrotoluene destruction consists in influencing trinitrotoluene in water medium with alkaline chemical reagents - water solutions of sodium sulphite and sodium hydroxide with concentration 5-20%, with weight ratio trinitrotoluene: chemical reagent, equal 1:3-30, and simultaneous impact with ultrasonic fluctuations with frequency not lower than 20 kHz and intensity not lower than 2,5 W/cm2; and at initial temperature 40-50°C heating is realised due to absorption of energy of ultrasonic fluctuations to temperature 80-85°C.

EFFECT: invention provides complete decomposition of explosive substance, absence of toxic organic products and high rate of the process.

9 dwg, 1 tbl

FIELD: power industry.

SUBSTANCE: heat-mass-energy exchange method consists in formation of vortex annular flows of media, their direction parallel to each other with provision of partial contact of opposite directed external surface layers in radial and tangential directions to the depth providing their acoustical excitation due to deformation-shear interaction, and further combination of excited flows. One of the vortex annular flows is additionally directed in an opposite direction to the rest ones along their axes. A heat-mass-energy exchange device containing two pipes with tangential inlets, which are interconnected with each other by partial intersection along generatrixes, and an acoustical chamber; with that, tangential inlets and the outlet of one of the pipes are located in an opposite direction in relation to the tangential inlets and outlets of the rest pipes.

EFFECT: invention provides for additional excitation of flows in the zone of their contact and increase of heat-mass-energy exchange intensity.

2 cl, 6 dwg

FIELD: chemistry.

SUBSTANCE: invention relates to obtaining biocompatible magnetic nano-particles and can be applied for therapeutic purposes, in particular, for fighting cancer. Method of obtaining nano-particles, including iron oxide and silicon-containing casing and having value of specific absorption rate (SAR) 10-40 W per g of Fe with field strength 4 kA/m and frequency of alternating magnetic field 100 kHz, contains the following stages: A1) preparation of composition of at least one iron-containing compound in at least one organic solvent; B1) heating of composition to temperature in range from 50°C to temperature 50°C lower than temperature of reaction of iron-containing compound according to stage C1 for minimal period 10 minutes; C1) heating composition to temperature between 200°C and 400°C; D1) purification of obtained particles; E1) suspending purified nano-particles in water or water acid solution; F1) addition of surface-active compound to water solution, obtained according to stage E1); G1) processing of water solution according to stage F1) by ultrasound; H1) purification of water dispersion of particles, obtained according to stage G1); I1) obtaining dispersion of particles according to stage H1) in mixture of solvent from water and water-mixable solvent; J1) addition of alkoxysilane into dispersion of particles in mixture of solvent according to stage I1); and K1) purification of particles.

EFFECT: invention makes it possible to obtain biocompatible magnetic particles with high value of specific absorption rate (SAR).

42 cl, 3 dwg, 9 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to a method for preparing a soluble concentrate of deer-breeding antler by-products. The method for preparing the soluble concentrate of deer-breeding antler by-products involving water extraction of raw materials when exposed to ultrasonic vibrations at a ratio of raw materials: water 1:3 for male deer tails and/or reproductive organs, 1:1 for uterus with foetuses and amniotic fluid; that is followed by filtration and vacuum drying, under certain conditions.

EFFECT: method provides higher yield of the end product and keeping the natural properties of the raw material and a high degree of water-solubility.

3 tbl, 3 ex

FIELD: textiles, paper.

SUBSTANCE: invention relates to a device for reducing the torque and/or speed of the turbulent liquid, for example, in a clearing agent. It can be used during precipitation or separation of suspended solid particles from liquid, such as in urban water treatment systems, treatment of sugarcane juice or in pulp and paper manufacturing. The device for reducing turbulence caused by the flow of the first liquid from the tube or hose into the second liquid in the tank. The device is made with the ability of immersion into the second liquid, the first and second liquids may be identical or different, and the said device comprises: the first and second rigid plates, one or more spacers, each of which is attached to both the first plate and the second plate, at least four partitions rigidly attached to the second plate, at that the partitions are located symmetrically with respect to axis which extends through the centre of the hole in the first plate, and which is also perpendicular to both said plates, and there are spaces between adjacent partitions, which enables a certain amount of liquid to pass between the adjacent partitions. The first and second plates have approximately the same size and shape, except that the first plate has a central hole through which a tube or hose may extend, so that the tube or hose is mounted for outputting the first liquid into the space between the first and second plates. The spacers hold the first and second plate in a fixed position relative to each other and parallel to each other. The second plate is made with the ability to divert the flow of the first liquid approximately by 90 degrees, converting approximately the linear flow, which is approximately parallel to the axis, into the radial outwardly directed flow which is approximately parallel to the second plate, and the partitions are additionally made with the ability of power dissipation of the first liquid flow, to prevent turbulence at the interface between the first and second liquids and to prevent the formation of vortices. The clearing agent for precipitation or separation of suspended solid particles from the liquid, containing a tank, in which a plurality of devices for reduction of turbulence is mounted.

EFFECT: increased efficiency of separation.

19 cl, 1 dwg, 3 ex