Composition particles, compositions and methods

FIELD: chemistry.

SUBSTANCE: invention relates to cosmetic industry and provides a composition for depositing on keratin surfaces, which contains composition particles in the form of fused agglomerates having a part containing at least one dye and a part containing at least one transparent and translucent thermoplastic material, where the composition particles contain, based on the weight of all of the powdered composition material, about 10 to 90 parts of the dye part and about 90 to 10 parts of the transparent and translucent thermoplastic material part, and a method of producing the powdered composition material.

EFFECT: invention enables to obtain cosmetic compositions which will have an improved outer appearance on the skin and fewer SKU.

23 cl, 10 tbl, 11 ex

 

Cross-reference to related applications

This application claims the priority of provisional patent application U.S. No. 61/296348, filed January 19, 2010, and provisional patent application U.S. No. 61/357809 filed on 23 June 2010.

Area of technology

The invention relates to the field of powder materials and their use in cosmetic compositions with improved appearance to keratin surfaces.

Background for the creation of inventions

A high percentage of women uses the Foundation makeup. Modern commercial products have excellent quality and are available in shades that are properly aligned with the skin color. However, users fundamentals remain unmet. For example, a high percentage of ethnic women uses as a basis, however, they are not satisfied with sallow, livid tone that she often gives their skin. Often these products contain significant amounts of titanium dioxide, which provides excellent coverage, but it can create a look that is similar to the mask. This is probably partly because of the shades of colour that provide the appearance of heat or cold in addition to depth and a number of qualitative characteristics. The basis of make-up that masks natural skin tones, cha�then becomes the reason for what fascial skin seems unnatural, because it hides the natural diversity of the qualitative characteristics of the skin. There is a great need in makeup products such as foundations that provide coverage without masking the skin tones, which gives it an undesirable appearance, like a mask.

Another reason for the importance of the formulation of such a framework - the need to reduce SKU's ("unit inventory"). To meet the needs of all users of the cosmetic company needs to develop a formulation for a wide color selection framework, to meet the needs of their customer base. Many of these shades are sold very poorly, or not sold at all. A large number of units of SKU means higher costs for the manufacturer of cosmetics. Thus, there is interest in the preparation of the compositions of the products of the basics of makeup that will match a wide range of skin tones. Reduced SKU profitable as a cosmetic company and the consumer. Additionally, this eliminates confusion associated with color selection by the consumer, which is never easy. Besides more units SKU means higher cost for the consumers, because the high price of goods reflected in higher retail�th price for consumers.

Found that when color cosmetics are prepared with specific types of composite particles, which have a share of transparent or translucent thermoplastic material in the particle, the color cosmetics will have an improved appearance of the skin, including enhanced expression of a number of qualitative characteristics, depth and skin tones, and reducing sallow, pale or like a mask type of color cosmetics such as Foundation makeup. In addition, the composite particles facilitate the reduction in the number of shades of color cosmetics that are required to match all skin tones in tonal lines.

The purpose of the invention is to provide color cosmetic compositions that are more "universal", which means that a specific color will correspond to a larger number of color shades in tonal categories. For example, the base, which can be considered more versatile in its properties matching shades can be designated as Color # 1, and she can match the shades of colour 1, 2 and 3 colouring in the category of "Light" as opposed to the need in three different shades in the light category with traditional Foundation makeup.

An additional objective of the invention is to provide a composite particle containing fraction to�acitelli and transparent or translucent thermoplastic share.

An additional objective of the invention is to provide a composition for application to keratin surfaces such as skin, hair or nails, containing composite particles.

An additional objective of the invention is to provide a method of improving the appearance of depth, number of quality characteristics and skin tones by providing color cosmetics natural look, which contains composite particles.

An additional objective of the invention is to provide a method of reducing ashen, livid or similar to mask the appearance of the compositions such as Foundation makeup, skin by preparing a composition of composite particles.

An additional objective of the invention is to provide a method of reducing the number of SKUs in the assortment of shades of colour cosmetics by preparing a colored cosmetic composition particles.

Summary of the invention

The invention relates to a composition for application to keratin surfaces containing composite particles in the form of a fused agglomerate having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, where the composite particles contain, by weight of the total composition of powdered material from the eye�about 1 to 99.9 parts in the proportion of the dye and from about 0.1 to 100 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of the composite particles present in the composition, have a share of the dye.

The invention further relates to a composite particle in the form of a fused agglomerate having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, where the composite particles contain, by weight of the total composite material, from about 1 to 99.9 parts in the proportion of the dye and from about 0.1 to 100 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of thermoplastic material in the powder material is in the form of solid or hollow, partial or complete spheres.

The invention also relates to a method of imparting color to the skin while improving the appearance of a number of qualitative characteristics, depth or skin tones by applying a composition containing composite particles having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material.

A method for reducing the effect of pipalkoti, ghastly pallor or similarities with mask color cosmetic compositions for the skin containing a substitution of from 0.1 to 99%, preferably 10-90% of the total component of the CRA�of RER, the presence in the composition, the composite particles having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, where the composite particles contain, by weight of the total composite material, from about 1 to 99.9 parts in the proportion of the dye and from about 0.1 to 100 parts of a fraction of a transparent or translucent thermoplastic material.

A method for reducing the number of SKUs in the assortment of shades for cosmetic product containing a provision of the cosmetic product, where from 0.1 to 99%, preferably 10-90% by weight of the total component of the dye, amount of composite particles.

DETAILED description of the INVENTION

I. Description of figures

Fig.1:Depicts the types of composite particles, which can be used in the compositions and methods according to the invention where the transparent area inside the black lines represents the proportion of transparent thermoplastic material of the composite particles and splosna the black part represents the proportion of the dye composite particles.

1(A): represents the composite particle in the form of a fused agglomerate, where thermoplastic material is in the form of hollow or solid spheres, so that when these spheres interact with the solvent and the dye with the formation of com�ositional particles, at least some proportion of thermoplastic material remains in the form of whole or partial fields.

1(B): is a composite particle in an encapsulated form, where the proportion of the colorant is encapsulated in the proportion of a thermoplastic material, and where the composite particle is essentially spherical in shape.

1(C): is a composite particle in an encapsulated form, having a non-spherical shape is depicted as essentially octagonal - and where the proportion of the dye is the deposition of irregular shape embedded in a thermoplastic material.

1(D): is a composite particle in encapsulated form, with an irregular shape and having a proportion of the dye encapsulated inside.

Fig.2:Depicts a composite particle in the form of a compressed microspheres. The sphere that more depicts the unprocessed transparent or translucent hollow microsphere with a deformable polymeric shell and enclosed within it is able to increase in volume of the fluid. The smaller sphere on the right shows a stacked polymer shell of prisoners inside the solid particles of the dye and liquid-tight coating.

Fig.3:Depicts a diagram that shows a decrease in the number of units of SKU basics of makeup, achieved with formulations� bases, made with composite particles according to the invention (11 shades that are consistent with all skin tones), compared with a palette of shades of MAC Studio Fix Fluid SPF 15 (19 shades necessary to fit all skin tones). Thus, a 42% decrease (8 shades) in units of the SKU.

II. Definitions

In used in this description, the terms, the singular includes the plural and Vice versa.

Everything mentioned in this description relative shares are percentages by weight, unless otherwise indicated.

The term "agglomerate" means relates to a composite particle, cluster of dyes and a transparent thermoplastic material, where the clusters are fused, for example chemically or physically associated with each other.

The term "earthy" or "livid" means whitish like ashes appearance, cosmetics, such as Foundation, can manifest on the skin, especially on darker skin.

The term "transparent" means the same thing as "translucent", and that thermoplastic material makes possible the passage of light and also quite free from turbidity or turbidity to provide a clear view of what lies behind it. In some cases, thermoplastic materials used in the compositions and methods of the invention may be transparent in the form of individual particles or SFU�algebraic particles however, when I see them in bulk density, they may look whitish or grayish powder. In this case, the determining factor is the kind of individual particles.

The term "compressed microsphere" means initially, a hollow microsphere, in which the production process has formed the channels and crevices in which dyes are captured and dispergirovannykh throughout the volume. Each individual microsphere containing buried and captured by the dye forms its own closed system. In contrast, in the fused agglomerates deposition of the dye is in the agglomerates, which are fused with the agglomerates formed from a transparent thermoplastic material.

Used in this description, the term "dye" means colored pigments or unpainted or white particles which are sometimes used as fillers or to mute the color in cosmetic compositions. Generally, the term "dye" excludes transparent or translucent thermoplastic materials in the form of particles.

The term "dye component" means the total number of dyes, which are described in section II below which are present in the composition.

The term "composite particle" means a solid particle, which contains a fraction that contains at least one dye, and the fraction containing �ENISA least one transparent or translucent thermoplastic material, where two lobes fused together, i.e. are not present as simple unreacted mixture.

The term "encapsulated particle" means a type of composite particles, where the component of the dye encapsulated in transparent thermoplastic material.

The term "fused agglomerate" means in relation to a composite particle, what is the concentration of the dye and a transparent or translucent thermoplastic material, where the agglomerates are fused, for example, are associated chemically with each other. In the case where the transparent thermoplastic fraction of a fused agglomerate is in the form of hollow or solid spherical particles, fused agglomerate may contain thermoplastic fraction containing agglomerated partial or complete solid or hollow sphere.

The term "mask" refers to a color cosmetic composition such as Foundation, fascial the skin when the composition masks the skin tones to such a degree that gives it a visually unnatural appearance.

The term "room temperature" means a temperature of about 25°C.

The term "SKU" means the inventory unit, which is the smallest assortment unit. The number of SKUs, mostly, are in the format xxxx-XX, where the first four members shall mean the name of the product and to color cosmetics, the last two members�and - code shade. For example, a SKU number 1234-56 means, for example, that the line "x" product basics of makeup marked as number 1234 and the number "56" refer to one specific shade of Foundation makeup.

The term "translucent" means in relation to thermoplastic material that allows the passage of light, but has enough turbidity or turbidity obstructing a clear view of what lies behind it. In some cases, when thermoplastic material is in the form of individual particles, the particles can be translucent, but when you see them in bulk density, such translucent particles may appear as whitish or grayish powder. In this case, the determining factor is the kind of individual particles.

III. Composite particle

A. Description

The composite particle can be in the form of agglomerate, preferably a fused agglomerate, compacted microspheres or encapsulated particles.

Code composite particle is in the form of a fused agglomerate, it is usually produced by sculpturing a mixture of one or more colorants and one or more transparent or translucent thermoplastic synthetic or natural polymeric materials to create a composite that retains the properties and the colorant, and thermoplastic material. Preferably, cu�sitali and transparent or translucent thermoplastic material, used for producing composite particles are in powder form.

Composite particle is solid at room temperature and has a particle size in the range of from about 0.01 to 200, preferably from about 0.1 to 150, more preferably from about 1 to 100 micrometers in diameter. Composite particle can have a variety of shapes, including spherical and other types of irregular shapes. Composite particle preferably contains a proportion of dye in the range of from about 0.1 to 99%, preferably from about 0.5 to 90%, more preferably from about 0.5-80%, and a transparent or translucent thermoplastic share in the range of from about 0.1 to 100%, preferably from about 0.5 to 90%, more preferably from about 0.5 to 80%, relative to all percent by weight of the total composition of a powder material.

V. Components of the composite particles

1. Dyes

Dyes suitable for use for producing composite particles include organic pigments, which are usually called as colorants D&C and FD&C, such as blue, brown, green, orange, red, yellow, etc. These organic pigments may also include insoluble metallic salts of certified color additives, referred to as varnishes D&C or varnishes FD&C.

Suitable krassi�ate also include inorganic pigments, such as iron oxides, Ultramarines, dyes based on chromium or chromium oxide, and mixtures thereof. Iron oxides red, blue, yellow, brown, black and mixtures thereof are suitable.

Additional examples of suitable dyes include whether or not colored (for example white) non-pigmented powders. Examples include opaque or non-transparent particles, such as bismuth oxychloride, titanate mica, colloidal silica, spherical silica, polymethylmethacrylate, micronized Teflon, boron nitride, acrylate copolymers, aluminum silicate, aluminum starch octenylsuccinate, bentonite, calcium silicate, cellulose, chalk, corn starch, diatomaceous earth, smectite, glycerol starch, hectorite, hydrated silica, kaolin, mixed silicate of magnesium-aluminum, magnesium trisilicate, maltodextrin, montmorillonite, microcrystalline cellulose, rice starch, silica, talc, mica, titanium dioxide, zinc laurate, zinc myristate, zinc resinat, aluminum oxide, attapulgite, calcium carbonate, calcium silicate, dextran, kaolin, nylon, similat silicon dioxide, silk powder, sericite, soy flour, tin oxide, titanium hydroxide, crimini phosphate, powder shells of walnuts or a mixture thereof.

Preferred dyes have resorcylic in the range of from about 0.001 to 150 microns, preferably from about 0.005 to 100 μm, more preferably from about 0.1 to 50 micrometers.

2. Transparent or translucent thermoplastic material

Transparent or translucent thermoplastic material is preferably a synthetic polymer. Typically, to provide the desired transparency or translucency, refractive index of the polymer material used for obtaining the composite is in the range of from about 1.3 to 1.8 or 1.4 to 1.6. In addition, transparent or translucent polymer is typically solid at room temperature and may have a density in the range of from about 0.5 to 5 grams/cm3. The polymer preferably has a melting point from about 50° to 200°C.

The material used for obtaining the composite may be in the form of hollow or solid spheres. Or it may be in the form of a solid block or film, which can be crushed to form particles of varying sizes and shapes. In one preferred embodiment of the invention, a transparent or translucent thermoplastic material is in the form of particles, which can be hollow or solid spherical particles, preferably having a particle size in the range of from about 0.01 to 150 μm, more preferably from 0.1 to 100 micrometer�in, even more preferably from 0.5 to 75 microns.

Suitable polymers for transparent or translucent thermoplastic material used in the production of composite particles include those that are described in this description, but are not limited to.

(a) Homo - or copolymers of unsaturated type ethylene monomers

(i) Acrylic acid, methacrylic acid or their basic esters

Suitable polymers include Homo - or copolymers of unsaturated type ethylene monomers, such as acrylic acid, methacrylic acid or their elemental With1-20aliphatic or aromatic esters. Examples of such monomers include methyl acrylate, methyl methacrylate, acrylate, ethyl acrylate, ethyl methacrylate, butyl acrylate, butyl methacrylate, hexyl acrylate, hexyl methacrylate, etc.

It is possible that the polymer was unsewn or partially cross-linked. If it is sewn, divinelvie crosslinkers in the form of alpha-omega dienes may also be appropriate, for example, agents having from 2 to 10 carbon atoms. Examples include Eten, propylene, butene, etc. If the polymer is crosslinked, it is likely that in contact with the solvent, the polymer will have a tendency rather to die than to full solvation. If the polymer was in the form of spherical particles, it will result to�ecou composite particle, where the proportion of thermoplastic, which is present, may contain either a partial or complete sphere. Likely that when a composite particle comprising a spherical part, this contributes to the unique visual effect of the composite particle.

One preferred polymer is polymethylmethacrylate (PMMA) in a spherical form, having a specific gravity in the range of from about 1,100 to 1,250 g/ml, a particle size in the range of from about 4.5 to 8.5 microns and a density in the range from 1 to 1.5 g/cm3. Such particles can be purchased from SEPPIC Corporation under the trade name Sepimat P and from Tomen American trading under the name Microsphere M-100.

Other types include styracaceae acrylates (copolymers of styrene and acrylic acid, methacrylic acid or their elementary C1-10esters), polymers of styrene with Acrylonitrile ("SAN") copolymers Acrylonitrile-butadiene-styrene ("ABS").

(ii) Homo - or copolymers of alkenes

Also suitable are Homo - or copolymers With2-10alkenes, such as polyethylene, polypropylene, polybutene and the like, which can be stitched. One suitable alkene is unsewn homopolymer of ethylene, sold under the trade name Performalene 400®, which is a high molecular weight polyethylene homopolymer sold by Baker Hughes.

(b)�carbonate

Also suitable as thermoplastic material used to produce the composite are different types of polycarbonates. The term "polycarbonate" means polymers having functional groups linked together by carbonate (-O-C(O)-O-) groups, and they can be polycyclic aromatic carbonates or paleoliticheskie carbonates. The polycarbonates can be in the form of solid or hollow spherical particles, crushed particles or in the form of a film or block.

3. Solvents

Suitable solvents for swelling or solvation of a transparent or translucent thermoplastic material can be determined by the elucidation of its solubility parameter of Hildebrand, which is the square root of the energy density of cohesion of the solvent. The formula for the solubility parameter of Hildebrand (δ):

δ=((HvRT)/Vm

expressed in (calories/cm3)1/2,

where Hv= heat of evaporation

R = gas constant

T = temperature

Vm= molar volume.

One type of solvent suitable for use in preparation of the composite powder one�brasego material, can be installed on its solubility parameter of Hildebrand. In this case, the solvents having a solubility parameter of Hildebrand in the range of from about 1 to 16, more specifically 3 to 15, more preferably 5-10 (calories/cm3)1/2can be good solvents for use in producing composite powder material.

Identification of suitable solvents for the selected thermoplastic materials may also be evaluated by the procedures described in "A Simple Solvent Selection Method for Accelerated Solvent Extraction of Additives from Polymers",Analyst.Volume 124, pages 1707-1719 - The Royal Society of Chemistry, 1999, included in this description by reference in its entirety.

Other types of preferred solvents include aliphatic, aromatic or heterocyclic, saturated or unsaturated hydrocarbon chains in the range of from about 1 to 12, preferably from about 1 to 10 carbon atoms, more preferably from about 2 to 8 carbon atoms. Such carbon chain may have one or more links, such as carbonyl, hydroxyl, amine, halogen, ether, or amide group, substituted on the hydrocarbon chain. Examples of such solvents include acetone, xylene, methyl ethyl ketone (MEK), dimethylformamide, dimethylglutaric, trichloroethylene, trichloromethane, methanol, ethanol, isopropanol, ethyl acetate, BU�racethat, toluene, benzene, cyclohexane, amyl acetate, carbon tetrachloride, tetrahydrofuran, datetoday alcohol, ethylene dichloride, methylene chloride, DMSO, morpholine, cellosolve, pyridine, propanol, or C1-4mono - or dialkylamino ethers of ethylene glycol, and the like. Most preferred are ethanol, acetone, xylene or MEK. Most preferred is acetone.

C. how to obtain

Composite particle in the form of a fused agglomerate can be obtained by combining a thermoplastic material and a dye when mixed with a quantity of solvent sufficient to cause swelling of thermoplastic material (e.g., expansion) or solvation. The ratio of thermoplastic material, dye and solvent can be found by determining the specific thermoplastic material, the quantity in which it is present, and what will be the most suitable solvent for swelling or solvation of a thermoplastic material. Typically, a suitable ratio of the colorant, a thermoplastic material, and solvent can be between about 0.1-50 parts of the dye of 0.1-100 parts of thermoplastic material, and 0.1 to 100 parts of solvent. Preferably, the process is carried out at room temperature, although, if desirable, can be applied warm. Dye, solvent and �termoplastici material combine at the time sufficient to allow thermoplastic material to swell from the solvent or salvationists. The time period may be in the range from 1 to 72 hours, or from 10 to 50 hours. After an appropriate period of time the mixture is removed from the vessel and spread on a glass substrate to form a flat surface, and then enable to dry for about 12-72 hours, preferably 24 to 48 hours, or until firm. The solidified mixture is then removed from the substrate and destroy the hands into small pieces. These pieces subjected to various treatments, such as milling and sieving to obtain composite particles having the desired shape and size.

The proportion of the dye and the portion of thermoplastic material of the composite particles of the alloy, so that the whole composite is in the form of particles. In a preferred embodiment of the composite particle can appear as a fused agglomerate component, the dye component and a thermoplastic material, and where the latter will detect the parts that are in sposhnoy or hollow partial spherical shape, that is, areas that have swelled, but did not fully collateralise in the production process.

If desired, the composite particles can be coated with various materials to make �x more hydrophobic or hydrophilic as desired. Suitable coatings include, but without limitation listed, oils, structuring agents and any one or more of the ingredients, additionally listed in this description, as suitable for use in cosmetic compositions according to the invention. Additional examples include silicone elastomers, silicone resins, silicone gums, synthetic or natural waxes, and the like. If the composite particles are coated, the coating is preferably from about 0.1 to 45%, more preferably from about 0.1 to 30%, most preferably from about 1 to 10% by weight solid composite particles. One particularly preferred coating is trisiloxane/Dimethicone, sulilat.

D. Another embodiment of the composite particles

Also suitable is a composite particle in the form of a compressed microspheres. Such particles are disclosed in patent publication U.S. No. 2009/0155371 included in this description by reference in its entirety. In this case, the transparent or translucent thermoplastic material is in the form of compacted microspheres with dye rather completely enclosed in the bead than forming part of the agglomerate. The compressed bead may be optionally covered with a membrane or coating in the same manner as described for the form �melted agglomerate composite particles. Such composite particles in the form of compressed microspheres can be obtained by:

(a) forming generovanou mixture by mixing or simultaneously, or sequentially in any order: (1) a transparent or translucent hollow microspheres having internal channels, preferably in the form of open cells, which have a deformable polymeric shell having enclosed in it can increase in volume of the fluid, (2) polar organic solvent, can cause swelling, but not dissolving the polymeric shells of the hollow microspheres, and (3) dyes, where the microchannels formed in the swollen polymer membranes, to make possible the access of dyes into hollow microspheres and exit of them are able to increase in volume of the fluid, thereby producing microspheres, each of which contains a compressed polymeric membrane in the gel state and has one or more of these dyes contained in it;

(b) remove the ability to swell in volume of the fluid and the polar organic solvent from generovanou mixture and

(C) coating the microspheres film-forming material for forming on them impervious to liquid coatings.

In the resulting compressed microsphere particles of the dye encapsulated in the microspheres. In some cases�, the dye used may be in the form of particles of submicron size, in this case compressed microspheres can have an average particle size, which can be at least 10 times, preferably 20 times, more preferably 50-fold and most preferably 100 times greater than the average particle size of the colorant used to obtain composite particles.

The capture of the pigment particles is achieved in the present invention primarily by providing a transparent or translucent hollow microspheres, which has a deformable polymeric shell and which may or may not be able to increase in volume of the fluid inside the hollow portion of the microspheres. The microspheres are then mixed or sequentially in any order or simultaneously with a polar organic solvent that can cause swelling, but not dissolving the polymeric shells of the hollow microspheres and solid particles that need to be captured. Thereby forming generovanou mixture, which contains microspheres with a polymeric membranes in gel state, which are swollen enough so to have micro-channels or through-holes formed in them to allow the dye particles to enter into the microspheres. Such micro-channels or through holes in rabbuh�x polymeric shells of the microspheres also give the opportunity to exit is able to increase in volume of the fluid environment of the microspheres, thereby causing immediate compression or reduction of the polymer shells and fine particles of the dye inside the microspheres. Then able to increase in volume of the fluid and a polar organic solvent removed from generovanou mixture. Preferably, but not necessarily, the film-forming material is applied over the compressed polymeric membranes to form on them impermeable membrane, which serves for insulation compressed polymeric shells of the microspheres from any solvent in the environment, which can cause swelling or otherwise affect the structural integrity of such polymeric membranes. Thus, the solid particles can be securely captured within the microspheres with little risk or no risk of seepage to the outside.

The hollow microspheres used as a transparent or translucent thermoplastic material, in its original form (i.e., prior to mixing with the solid particles and the polar organic solvent) are preferably capable of expanding hollow polymeric microspheres, each of which contains a deformable polymeric shell which is impermeable to gas and is enclosed or encapsulated in it is able to increase in volume of the fluid. When heated for�connected or encapsulated fluid may increase in amount, creating pressure against the inner wall of a deformable polymeric shell. At the same time, increased temperatures can cause softening of the polymeric shell, thereby causing the expandable microspheres full like a balloon.

Deformable polymeric shells of the hollow microspheres can be formed from any sinteticheskogo or natural sewn or unsewn polymer. If the polymer is crosslinked, preferably, that it was poorly sewn. Preferably, but not necessarily, the polymeric shells of the hollow microspheres contain at least one synthetic polymer obtained by polymerizing one or more unsaturated type ethylene monomers to form homopolymers or copolymers of unsaturated type ethylene monomers, or copolymers of unsaturated type ethylene monomers and one or more organic groups. Examples of the unsaturated type ethylene monomers that may be suitable include, for example, vinylidenechloride, vinyl chloride, Acrylonitrile, acrylic acid and its corresponding C1-C20aliphatic or aromatic esters, methacrylic acid and its corresponding C1-C20aliphatic or aromatic esters, acrylamide, methacrylamide, vinylpyrrolidone, alkenes such as styrene, ethylene, prop�len, butylene, methylpentene, 1,3-butadiene and the like. Polymeric shells of the hollow microspheres may also be formed of suitable synthetic polymers such as polyesters, polyamides, polyphthalamide, polyimides, polycarbonates, polyketone, cellulose acetate, polysulfones, polyphenylenesulfide, polyphenyleneoxides, polylactic acid, polyvinylpyrrolidone, polystyrene, polyacrylonitrile, polyacrylamide, polyacrylates and copolymers of these polymers. In a particularly preferred embodiment of implementation, the deformable polymeric shells of the hollow microspheres formed of copolymers other vinyl chloride, of Acrylonitrile and/or methylmethacrylate.

Able to increase in volume of the fluid inside the hollow microspheres of the present invention can be any suitable gas (e.g., air or nitrogen) or volatile liquid hydrocarbons (e.g., isobutane or isopentane). Preferably capable of expanding fluid is selected from the group consisting of air, nitrogen, isobutane and isopentane. More preferably, capable of increasing in volume the fluid is either isobutane or isopentane.

Hollow microspheres having a deformable polymeric shell containing copolymers other vinyl chloride, Acrylonitrile and methylmethacrylate, with the ability to swell in volume those�OCHA environment containing isobutane or isopentane, commercially available under the trade name EXPANCEL® from Expancel, Inc. at Duluth, Georgia. Hollow microspheres EXPANCEL® is available in various forms, for example, dry, wet, non-expanded or pre-stretched. As dry non-expanded microspheres (EXPANCEL® DU) and dry expanded microspheres (EXPANCEL® DE) can be used in the present invention for grasping and stabilizing solid particles. Microspheres EXPANCEL® DU have an average particle size in the range of from about 6 to about 40 micrometers and a density of about 1-1. 3 g/cm3. Microspheres EXPANCEL® DE have an average particle size in the range of from about 20 to about 150 micrometers and a density of about 0.03-0.07 g/cm3.

Suitable solvents for preparation of composite particles in the compressed form of microspheres having dispersed dyes in them, are those specified in relation to a fused agglomerated composite particles described above, and in the same regular amounts.

When mixed with untreated hollow microspheres polar organic solvent can cause significant swelling of the polymer shells of the hollow microspheres and thereby translate impervious to gas, polymer raw shell of the hollow microspheres in generowanie condition with multiple microchannels or pores, �obrazovavshijsya in them.

The dyes used to create a compressed microspheres are the same as those specified in relation to the fused agglomerate and in the same regular amounts.

It is possible to enter in the microsphere two or more different types of dyes to create unique visual effects. In one specific embodiment of the composite particles, two or more different types of pigment particles is introduced into the microspheres.

Preferably, when the composite particles are in the form of compressed microspheres, the average particle size of the used dyes should be significantly smaller than the size of the hollow microspheres, so that the dyes can easily enter and be captured by hollow microspheres, which form a transparent thermoplastic material. Preferably, the average particle size of the colorant is less than about 1 micrometer, more preferably from about 0.001 micrometer to about 0.1 micrometer and most preferably from about 0.01 to about 0.05 micrometer.

Hollow microspheres, the solvent and the dye, which is explained in the description, are mixed together simultaneously or sequentially to the formation of generovanou mixture. If consistently mixed, the ingredients can be added and mixed in any suitable order. For example, the first can be mixed VM�glass hollow microspheres and the dye, followed by addition of a solvent to form a suspension. Another example, the first dye may be dispersed in the solvent and then mixed with hollow microspheres. Another example, first, the hollow microspheres can be added to an organic solvent for gel formation, and then the dyes are added to the gel. In any case, all the ingredients are mixed well until a homogeneous mixture. The mass ratio between the hollow microspheres and the polar organic solvent is preferably from about 1:3 to about 1:100 and more preferably from about 1:20 to about 1:50, so that the polymeric shells of the hollow microspheres may be greatly swollen by solvent. The mass ratio between the dyes and hollow microspheres can be in a wide range from about 1:10 to about 100:1, preferably from about 2:3 to about 10:1 and more preferably from about 1:1 to about 2:1.

As polymeric shells of the hollow microspheres consist of unsewn or weakly crosslinked polymer, the solvent molecules that are sufficiently small in comparison with the polymer molecules can penetrate between the polymer chains to break intermolecular bonds between adjacent polymer chains and pull apart the polymer chains from one another. Therefore, polymeric shells of the hollow microspheres are subjected to swelling of the polar organic solvent, so that the obra�comfort generovanou mixture, which contains a porous network unconnected polymer chains extending in the amount of the solvent or dispersed in it. Polymeric shells of the hollow microspheres in this gel state are no longer impervious to gas, but become porous, i.e., sufficiently large microchannels in them, through which the dye has the ability access quite swollen microspheres. At the same time is able to increase the amount of fluid come out of the microspheres through the microchannels, causing generowanie polymer sheath to contract or shrink and leading to a result in which the shrinkage of the microspheres with a significantly reduced total volume. Thus, the dyes are captured within compressed polymer shells which gave the shrinkage of the microspheres.

These gave the shrinkage of the microspheres can have an average particle size in the range of from about 1 to 15 microns and better from about 5 micrometers to about 8 micrometers. Given the shrinkage of the microspheres significantly smaller than untreated hollow microspheres. In addition, given the shrinkage of the microspheres are no longer hollow, but they are now filled with pigment particles with the remaining small voids or without them. At the same time, the polymer shell of the microspheres remain in the gel state, i.e. swollen through� polar organic solvent. It is important to note that given the shrinkage of the microspheres of the present invention, although morphologically modified and master the process of gelation, remain in generovanou mixture as single particles with a small coalescence or without it. Subsequent drying generovanou mixture gives so loose powders that contain microspheres with well-defined surface boundaries and minimal clumping or agglomeration.

Described in this application, the process of gelation is fundamentally different from the well-known process of the Sol-gel. In a typical process the Sol-gel alkoxide precursors of the metal and the metal chloride is first solubilizer to the formation of a solution (Sol) and then subjected to the reactions of hydrolysis and polycondensation for the formation of a colloidal system consisting of solid particles dispersed in a solvent, with subsequent deployment in the direction of formation of inorganic mesh containing a liquid phase (gel), which can be dried to remove the liquid phase from the gel thus forming a porous material. On the contrary, the process of gelation of the present invention provides a hydrolysis reaction or polycondensation, and it forms a mesh water-insoluble polymer chains dispersed in polar organic solvent.

Generowania �rity, described above, can be subjected to degassing, during which generovanou the mixture was placed in conditions of reduced pressure or vacuum so as to remove the ability to swell in volume of the fluid from generovanou mixture. Then a second solvent which is miscible with the polar organic solvent used in the swelling/gelatin microspheres may be added to degassed generovanou mixture with sufficient stirring, to "redeem" generovanou mixture by separating the swollen microspheres from each other. For example, when the polar organic solvent is acetone and the second solvent can be water, which is miscible with acetone. Thanks nesmeshivaemost between the polar organic solvent and the second solvent, the microspheres become more spatially separated from each other and therefore more dispergirovannykh. This additional dispersion minimizes the risk of coalescence during the subsequent drying generovanou mixture. Additional separation of the microspheres can be achieved stage filtration or centrifugation, which is optional for the purpose of this invention.

After stages of degassing and quenching, as the polar organic�th solvent, and the second solvent is preferably removed from generovanou mixture to obtain a dry free-flowing powders containing microspheres with solid particles enclosed in them. The removal of polar organic solvent and the second solvent can be easily achieved with various techniques of separation and/or drying, is well known in the art, such as decantation, centrifugation, filtration, solvent extraction, air drying, vacuum drying, drying, drying by spraying, drying in a fluidized bed, drying supercritical fluid and the like. Polymer membranes that were pre-exposed to polar organic swelling solvent and become porous with microchannels passing through, give considerable shrinkage and lose their porosity after drying. In other words, the microchannels formed through swollen polymeric shell of the microspheres during the stage of gelation, closed after the drying step, thereby securely capturing the pigment particles within the microspheres. To minimize agglomeration between the dry microspheres, powders obtained can be further subjected to grinding and sieving through one or more sieves.

To exclude or minimize the potential risk of prozac�tion captured by the pigment particles from the dried microspheres, the obtained composite particles can be coated or subjected to other surface treatment. Suitable coverts ingredients include those stated in this description, such as silicones, waxes, oils and the like, which are described in relation to ingredients that are suitable for use in the compositions according to the invention. When the composite particle is in the form of compacted microspheres, preferably, the coating was impervious to the fluid to prevent the flow of any fluid into the microsphere and, as a consequence, the drip pigments present.

The obtained composite particles may have an average particle size in the range of from about 1 to about 50 micrometers, more preferably from about 1 to about 15 micrometers, and most preferably from about 5 to about 8 micrometers, as determined using the device for analysis of particle size Malvern, available from Malvern Instrument at Worcestershire, UK. The captured colors can range from about 10% to about 90% of the total weight of the composite particles 30% to about 75% by weight and most preferably from about 40% to about 60% of the total weight.

Fig.2 depicts schematic views of rough hollow microspheres microspheres 10 and 20 in accordance with one variant of implementation of the present invention, which is obtained about�abucay untreated hollow microsphere 10 according to the method described above. Specifically, untreated hollow microsphere 10 includes impervious to gas, and a deformable polymeric shell 12 with a prisoner inside of her capable of increasing in volume of the fluid 14. The diameter of the rough hollow microspheres of approximately 10 to 20 micrometers. On the contrary, the bead 20 of the present invention includes a compressed polymeric shell 22 prisoners inside pigment particles 24 and with impermeable membrane 24 is deposited on the surface. The diameter of the microspheres 20 are significantly less than the diameter of the rough hollow microspheres 10 and is approximately in the range of from about 5 to about 8 micrometers.

Also suitable are composite particles in the form of encapsulated pigments, such as particles, which are disclosed in U.S. patents No. 5223250, 5531985, 5587148 and 5733531, they are all included in this description by reference in its entirety.

IV. Cosmetic composition

Composite particles can be used for cooking a variety of compositions suitable for application to the keratin surface, including, but without limitation listed, creams, lotions, sunscreens, Foundation makeup, concealer, eyeshadow, blush, eye shadow, mascara and eyebrows, lipstick, lip gloss, nail Polish, products for hair�, such as shampoo, conditioner, products for hair styling, and so on. The compositions can be in the form of aqueous gels or of dispersions, emulsions or anhydrous compositions in liquid, semi-solid or solid form. Suitable aqueous gels contain from about 0.1 to 99% water and from about 1-99,9% other cosmetic ingredients. Emulsions can be oil in water or water in oil and typically contain from about 0.1 to 99% water and from about 1 to 99% oil. Anhydrous compositions generally contain less than about 1% water in addition to 0.1 to 90% of oils and other optional ingredients. Such compositions can contain one or more of these ingredients.

Typically, compositions, where a common component of the colorant contains from about 30 to 70 parts, preferably 40 to 60, most preferably about 50 parts of iron oxide to about 70-30, preferably 60-40, most preferably about 50 parts of thermoplastic material, provide desirable color effect, resulting in a natural appearance of the applied layer. Expressed otherwise favourable colour effect can be achieved by combining about 50-80 parts composite particle, more preferably about 2/3 of the composite particles and about 20-50, more specifically about 1/3 parts of iron oxide.

A. Oil

Suitable oils include silicones, complex� esters, vegetable oils, synthetic oils, including, but without limitation, those specified in this description. Approximate quantities are from about 0.1 to 99%, preferably from about 0.5 to 95%, more preferably from about 1 to 80%. The oils may be volatile or non-volatile at room temperature are preferably in the form capable of fluid flow. The term "volatile" means that the oil has a measurable vapor pressure or vapor pressure at least about 2 mm Hg at 20°C. the Term "nonvolatile" means that the oil has a vapor pressure of less than about 2 mm Hg at 20°C.

I. Volatile oils

Suitable volatile oils generally have a viscosity in the range of from about 0.5 to 5 Centistokes at 25°C. and include linear or cyclic silicones, paraffinic hydrocarbons, or mixtures thereof.

(a) Volatile silicones

Cyclic silicones are one type of volatile silicone that can be used in the composition, including those having the following formula:

where n=3-6, preferably 4, 5 or 6.

Also suitable are linear volatile silicones, for example, having the General formula:

(CH3)3Si-O-[Si(CH3)2-O]n-Si(CH3)3

where n=0, 1, 2, 3, 4 or 5, preferably 0, 1, 2, 3, or 4.

Cilices�e and linear volatile silicones are available from various commercial sources, including Dow Corning Corporation and General Electric. Linear volatile silicones Dow Corning sold under the trade names Dow Corning 244, 245, 344, and 200 fluids. These liquids include hexamethyldisiloxane (viscosity of 0.65 Centistokes (abbreviated cSt)), octamethyltrisiloxane (1,0 cSt), decamethylferrocene (1,5 cSt), Dodecamethylcyclohexasiloxane (2 cSt) and mixtures thereof, with all viscosity measurements made at 25°C.

Suitable branched volatile silicones include alkyltrimethyl, such as metallisation, utillisation, propertisation, butultimately and the like. Metallisation can be purchased from Shin-Etsu Silicones and has a trade name TMF to 1.5, having a viscosity of 1.5 Centistokes at 25°C. Such silicones have the General formula:

where each R independently mean C1-4alkyl, preferably methyl.

(b) Volatile paraffinic hydrocarbons

Also suitable as the volatile oils are different linear or branched paraffinic hydrocarbons having 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 or 20 carbon atoms, more preferably 8-16 carbon atoms. Suitable hydrocarbons include pentane, hexane, heptane, decane, dodecane, tetradecane, tridecane and C8-20ISO-paraffins, which are disclosed in U.S. patents No. 3439088 and 3818105, both included in this description by reference.

Such paraffinic hydrocarbons to�available from EXXON under the ISOPARS trademark, and from the Permethyl Corporation. Suitable With12ISO produces Permethyl Corporation under the trade name Permethyl 99A. Commercially available With different16ISO-paraffins, such as isohexadecane (having the trade name Permethyl R), are also appropriate.

2. Non-volatile oils

A variety of nonvolatile oils are also suitable for use in the compositions according to the invention. Nonvolatile oils generally have a viscosity of more than about 5 to 10 Centistokes at 25°C and may have a limit viscosity up to about 1,000,000 Centistokes at 25°C. Examples of nonvolatile oils include, but without limitation:

1. Esters

Suitable esters are mono-, di - and triesters. The composition may contain one or more esters selected from the group, or mixtures thereof.

Complex monetary characterized as esters, obtained by the interaction of a monocarboxylic acid having the formula R-COOH where R is a saturated or unsaturated alkyl with a linear or branched chain, having from 2 to 45 carbon atoms, or phenyl, and alcohol having the formula R-OH where R is a saturated or unsaturated alkyl with a linear or branched chain having 2-30 carbon atoms, or phenyl. As alcohol and acid can be substituted by one or more hydroxyl groups. One or both of the two, acid or alcohol, can be�ü "fatty" acid or alcohol, and may have from about 6 to 30 carbon atoms, more preferably, 12, 14, 16, 18 or 22 carbon atoms in linear or branched chain, saturated or unsaturated form. Examples monoatomic oils that can be used in the compositions of the invention include hexyl laurate, the butyl isostearate, hexadecyl of isostearate, cetyl palmitate, isostearyl neopentanoate, stearyl heptanoate, isostearyl isononanoate, stearyl lactate, stearyl octanoate, stearyl stearate, isononyl isononanoate and so on.

Suitable complex dietary are the reaction product of dicarboxylic acid and aliphatic or aromatic alcohol or an aliphatic or aromatic alcohol having at least two substituted hydroxyl groups and a monocarboxylic acid. The dicarboxylic acid may contain from 2 to 30 carbon atoms and may be saturated or unsaturated form with a straight or branched chain. The dicarboxylic acid may be substituted by one or more hydroxyl groups. Aliphatic or aromatic alcohol may also contain from 2 to 30 carbon atoms and may be saturated or unsaturated form with a straight or branched chain. Preferably, one or more of the acid or alcohol is a fatty acid or alcohol, i.e. contains 12-22 carbon atoms. Dicarboxylic acid can also be an alpha hydroxycitrate. Difficult�th ether may also be in the form of a dimer or trimer. Examples diapiric oils that can be used in the compositions according to the invention include oils having a lower viscosity, for example, diisostearate malate, neopentylglycol dioctanoyl, dibutyl sebacate, dietary the dimer delineat, Dicetyl adipate, desacetyl adipate, diisononyl adipate, diisostearate the dimer delineat, diisostearate fumarate, diisostearate malate, dioctyl malate, and so on.

Suitable complex triesters contain the reaction product of citric acid and aliphatic or aromatic alcohol, or, alternatively, the reaction product of aliphatic or aromatic alcohol having three or more substituted hydroxyl groups with a monocarboxylic acid. As in the case with the above-mentioned mono - and diathermy, acid and alcohol contain from 2 to 30 carbon atoms and may be saturated or unsaturated straight or branched chain and may be substituted by one or more hydroxyl groups. Preferably, one or more of the acid or alcohol is a fatty acid or alcohol containing 12 to 22 carbon atoms. The examples of triesters include esters of arachidonic, citric, or beganovi acids, such as triaridis, tributyl citrate, triisostearate citrate, With three12-13alkyl citrate, tricaprylin, tricaprylin citrate, tridecyl begent, trict�dodecyl citrate, tridecyl beginat or tridecyl of cocoat, tridecyl isononanoate and so on.

Esters suitable for use in the compositions are described further in C. T. F. A. Cosmetic Ingredient Dictionary and Handbook, Eleven Edition, 2006, under the heading "esters", the text of which is incorporated into this description by reference in its entirety.

2. Hydrocarbon oils

It may be desirable to introduce into the composition one or more non-volatile hydrocarbon oils. Suitable nonvolatile hydrocarbon oils include paraffinic hydrocarbons and olefins, preferably those having more than about 20 carbon atoms. Examples of such uglevodorodnykh oils include24-28olefins, C30-45olefins, C20-40ISO-paraffins, hydrogenated polyisobutene, polyisobutene, polydecene, hydrogenated polydecene, mineral oil, pentahydrochloride, squalene, squalane, and mixtures thereof. In the preferred embodiment, the implementation of such hydrocarbons have a molecular weight from about 300 to 1000 daltons.

3. Glycerinate esters of fatty acids

Synthetic or naturally occurring glycerinate esters of fatty acids or triglycerides are also suitable for use in the compositions. And plant and animal sources can be used. Examples of such oils include castor oil, lanai�new oil, With10-18triglycerides, Caprylic/capric/triglycerides, sweet almond oil, apricot stone oil, sesame oil, camelina oil, oil seeds Alexandrian Laurel (Tamanu), coconut oil, corn oil, oil of cotton seeds, linseed oil, oil ink, olive oil, palm oil, nut oil bassia, rapeseed oil, soybean oil, grapeseed oil, sunflower oil, walnut oil, and the like.

Also suitable are synthetic or semi-synthetic glycerinate esters, such as mono-, di - and triglycerides of fatty acids, which are natural fats or oils that have been modified, for example, complex mono-, di - or triesters of polyols such as glycerol. In the example, a fatty (C12-22) carboxylic acid is subjected to reaction with one or more recurring glycerine groups: glycerol stearate, diglyceryl diisostearate, polyglyceryl-3-isostearate, polyglyceryl-4-isostearate, polyglyceryl-6-ricinoleate, diglyceryl of diolein, the glycerol diisostearate, the glycerol tetraisostearate, glycerol, tristant, diglyceryl distearate, linoleic acid glycerol, the glycerol myristate, glycerol of isostearate, PEG castor oils, PEG glycerol oleate, PEG the glycerol stearates, PEG glycerol, tallowate and so on.

4. Non-volatile silicones

Nonvolatile silicone oils, both water soluble and water insoluble, are also suitable for use in the composition. Such silicones preferably have a viscosity in the range of from about more than 5 to of 800,000 cSt, preferably 20 to 200,000 cSt at 25°C. Suitable water-soluble silicones include silicones with functional amino groups, such as amodimethicone.

For example, nonvolatile silicones may have the following General formula:

where each R and R' are independent, mean C1-30saturated or unsaturated alkyl with straight or branched chain, phenyl or aryl, trialkylsilyl, and each x and y independently mean 1-1000000 provided that there is at least one of the two either x or y, and A is the end link of alkylsilane.

Preferably, when A is the end link of methylsilane, especially trimethylsiloxy, and each R and R' independently mean C1-30alkyl with straight or branched chain, phenyl or trimethylsilyloxy, more preferably1-22alkyl, phenyl or trimethylsilyloxy, most preferably methyl, phenyl or trimethylsilyloxy, and the resulting silicone is Dimethicone, vinyldimethyl, diphenylmethan, fenitrothion or trimethylsilylamodimethicone. Other examples include computers�t alkyldimethyl, such as acidimeter and the like, where at least one R is a fatty alkyl (C12With14With16With18With20or C22), and the other R is methyl, and A is the end link of trimethylsiloxy provided that such alkyldimethyl is flowing liquid at room temperature. Fenitrothion can be purchased from Dow Corning Corporation under the trade name 556 Fluid. Trimethylsilylamodimethicone can be purchased from Wacker-Chemie under the trade name PDM-1000. Acidimeter, also referred to as liquid silicone wax may be purchased from Dow Corning Corporation as 2502 Fluid or from DeGassa Care & Surface Specialities under the trade names Abil stock Wax 9801 or 9814.

V. Moisturizers

The composition of the invention may also contain one or more moisturizers. If present, the approximate limits are from about 0.001 to 50%, preferably from about 0.01 to 45%, more preferably from about 0.05 to 40% by weight of the whole composition. Examples of suitable humectants include glycols, sugars and the like. Suitable glycols are in Monomeric or polymeric form and include polyethylene and polypropylenglycol, such as PEG 4-200, which are polyethylene glycols having from 4 to 200 repeating units of ethylene oxide, and C1-6alkalophile, still� as propylene glycol, butyleneglycol, pentylindol and the like. Suitable of sugar, some of which are also polyhydric alcohols, are also suitable moisturizers. Examples of such sugars include glucose, fructose, honey, hydrogenated honey, Inositol, maltose, mannitol, maltitol, sorbitol, sucrose, xylitol, xylose, trehalose, and so on. Also suitable are derivatives of urea or sugars, for example, Ethylhexylglycerin. In a preferred embodiment of the humidifiers used in the compositions according to the invention are C1-6preferably With2-4alkalophile, most preferably butyleneglycol.

C. Surfactants

If desirable, the composition of the invention can contain one or more surfactants. This is particularly desirable when the composition is in the form of an aqueous gel or emulsion. If present, the surfactant may be in the range of from about 0.001 to 50%, preferably from about 0.005 to 40%, more preferably from about 0.01 to 35% by weight of the whole composition. Suitable surfactants may be silicone or organic, nonionic, anionic, amphoteric or zwitterionic. Such surfactants include, but without limitation, those�asana in this description.

1. Silicone surfactants

Suitable silicone surfactants include organopolysiloxane polymers that have amphiphilic properties, for example, contain hydrophilic radicals and lipophilic radicals. These silicone surfactants can be liquids or solids at room temperature.

(a) Dimethiconol copolyol or alkyldimethylammonium copolyol

One type of silicone surfactant that may be used is the so-called dimethiconol copolyol or alkyldimethyl copolyol. This may be a surfactant of the type water in oil or oil in water, having gidropony/lipophilic balance (HLB) in the range of from about 2 to 18. Preferably, the silicone surfactant is a nonionic surface-active substance with an HLB in the range of from about 2 to 12, preferably from about 2 to 10, most preferably about 4 to 6. The term "hydrophilic radical" means a radical that, when substituted on an organosiloxane polymer main chain, attached to hydrophilic properties of the substituted portion of the polymer. Examples of radicals that will confer hydrophilicity, are hydroxy-polietilene, hydroxyl, carbon�s, and mixtures thereof. The term "lipophilic radical" means an organic radical, which, when substituted on an organosiloxane polymer main chain, attaches to the lipophilic properties of the substituted portion of the polymer. Examples of organic radicals that will confer lipophilicity are C1-40alkyl with straight or branched chain, fluorine, aryl, aryloxy, S1-40hydrocarbonates, hydroxy-polipropilene or mixtures thereof.

One type of suitable silicone surfactant has the General formula:

where p means 0-40 (the range including all numbers between and subranges such as 2, 3, 4, 13, 14, 15, 16, 17, 18 etc.), and PE is (-C2N4O)a-(-C3N6O)b-H, where a represents 0-25, 0-25 b means, provided that a and b cannot be simultaneously equal to 0, each x and y independently range from 0 to 1 million, provided that both cannot be 0 simultaneously. In one preferred embodiment of implementation, x, y, z, a and b are such that the molecular weight of the polymer ranges from about 5,000 to about 500,000, more preferably from about 10,000 to 100,000 and most preferably approximately about 50,000, and the polymer is in General referred to as Dimethicone copolyol.

One type of silicone surfactant is�I, in which R has a magnitude that the long-chain alkyl is of cetyl or lauryl, and surface-active agent in General referred to as cetyl Dimethicone copolyol or lauryl Dimethicone copolyol, respectively.

In some cases, the number of repeating units of ethylene oxide or propylene oxide in the polymer is also specified, for example, Dimethicone copolyol, which is also referred to as Dimethicone PEG-15/PPG-10, which refers to dimeticone having substituents containing 15 parts of ethylene glycol and 10 parts of propylene glycol on the main chain of the siloxane. It is also possible that one or more methyl groups in the General structure specified were substituted with longer alkyl chain (for example, ethyl, propyl, butyl, and so forth) or a simple ether, such as methyl ether, ethyl ether, propyl ether, butyl ether, and the like.

Examples of silicone surfactants are sold by Dow Corning under the trade name S Formulation Aid, having the CTFA name in accordance Cyclopentasiloxane (and) PEG/PPG-18/18 Dimethicone; or a surfactant Dow Corning 190, having the CTFA name in accordance PEG/PPG-18/18 Dimethicone; or Dow Corning 193 Fluid, Dow Corning 5200 having the CTFA name in accordance lauryl PEG/PPG-18/18 of matichon; or Abil stock EM 90 having the CTFA name in accordance of cetyl PEG/PPG-14/14 dimatik�n, sold by Goldschmidt; or Abil stock EM 97 having the CTFA name in accordance bis-cetyl PEG/PPG-14/14 Dimethicone sold by Goldschmidt; or Abil stock WE 09 having the CTFA name in accordance of cetyl PEG/PPG-10/1 Dimethicone in a mixture also containing polyglyceryl-4 isostearate and hexyl laurate; or KF-6011 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG-11 methyl ether Dimethicone; KF-6012 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG/PPG-20/22 butyl ether Dimethicone; or KF-6013 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG-9 Dimethicone; or KF-6015 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG-3 Dimethicone; or KF-6016 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG-9 methyl ether Dimethicone; or KF-6017 sold by Shin-Etsu Silicones having the CTFA name in accordance PEG-10 Dimethicone; or KF-6038 sold by Shin-Etsu Silicones, having the name according to CTFA lauryl PEG-9 polydimethylsiloxyethyl Dimethicone.

(b) Crosslinked silicone surfactants

Crosslinked silicone surfactants, which are often referred to as emulsifying elastomers are suitable. Usually these polyoxyalkylene silicone elastomers are crosslinked by organopolysiloxane that can be obtained by the reaction of accession with the cross-linking of georganopoulos containing at least one hydrogen atom connected� with silicon and polyoxyalkylene containing at least two unsaturated type ethylene group. In at least one embodiment of the implementation, polyoxyalkylene stitched organopolysiloxane get the reaction of accession with the cross-linking of georganopoulos containing at least two hydrogen atoms, each of which is associated with silicon, and polyoxyalkylene containing at least two unsaturated type ethylene group, optionally in the presence of a platinum catalyst, as described, for example, in U.S. patent No. 5236986 and U.S. patent No. 5412004, U.S. patent No. 5837793 and U.S. patent No. 5811487, the contents of which are incorporated into this description by reference.

Polyoxyalkylene silicone elastomers that may be used include sold by Shin-Etsu Silicones under the trade names KSG-21, KSG-20, KSG-30, KSG-31, KSG-32, KSG-33; KSG-210 which is a crosslinked polymer of Dimethicone/PEG-10/15, dispersed in Dimethicone; KSG-310 which is a crosslinked polymer PEG-15 lauryl Dimethicone; KSG-320 which is a crosslinked polymer PEG-15 lauryl Dimethicone, dispersed in isododecane; KSG-330 (the one mentioned above, dispersed in triethylhexanoin), KSG-340 which is a mixture of cross-linked polymer PEG-10 lauryl dimetikona and cross-linked polymer is PEG-15 lauryl dimetikona.

Also suitable polyglycerol�available silicone elastomers, such as those disclosed in PCT/WO 2004/024798, this publication is incorporated into this description by reference in its entirety. Such elastomers include Shin-Etsu's KSG series, such as KSG-710, which is a crosslinked polymer of Dimethicone/polyglycerol-3, dispersed in Dimethicone, or crosslinked polymers lauryl Dimethicone/polyglycerol-3, dispersed in various solvents, such as isododecane, Dimethicone, triethylhexanoin sold under Shin-Etsu trade names KSG-810, KSG-820, KSG-830 or KSG-840. Also suitable are silicones sold by Dow Corning under the trade names 9010 and DC9011.

One preferred emulsifier based on crosslinked silicone elastomer is a crosslinked polymer of Dimethicone/PEG-10/15, which offers superior aesthetic qualities, due to its elastomeric main circuit and surface-active properties.

2. Organic nonionic surfactants

The composition may contain one or more nonionic organic surfactants. Suitable nonionic surfactants include alkoxysilane alcohols or ethers, formed by the interaction of alcohol with alkalisation, usually ethylene or propylene oxide. Preferably, the alcohol is any fatty alcohol having from 6 to 30 at�MOU carbon. Examples of such ingredients include Steareth 2-100, which is produced in the interaction of stearyl alcohol and ethylene oxide, and the number of ethylene oxide units ranges from 2 to 100; Beheneth 5-30, which is produced during the interaction of BeginInvoke alcohol and ethylene oxide where the number of repeating units of ethylene oxide is 5 to 30; Ceteareth 2-100, obtained by reacting a mixture of catelouge and stearyl alcohol with ethylene oxide, where the number of repeating units of ethylene oxide in the molecule is 2 to 100; Ceteth 1-45 which is produced during the interaction of catelouge alcohol with ethylene oxide, and the number of repeating ethylene oxide units is 1 to 45; Laureth 2-100, resulting from the interaction of lauryl alcohol with ethylene oxide, where the number of repeating units of ethylene oxide is from 2 to 100, and so on.

Other alkoxysilane alcohols are obtained when the interaction of fatty acids and mono-, di - or polyhydric alcohols with alkalization. For example, reaction products of C6-30fatty carboxylic acids and polyhydric alcohols, which are the monosaccharides, such as glucose, galactose, methyl glucose and the like, with alkoxycarbonyl alcohol. Examples include polymer alkalophile, reacted with Glycerinum fatty acid esters, such as PEG glycerol oleate, PEG glycerol stearate; or PEG, such as the PEG dipolyhydroxystearate, where the number of repeating units of ethylene glycol is in the range from 3 to 1000. Also suitable are ethoxylated propoxycarbonyl derivatives of C6-30 saturated or unsaturated fatty acids, such as, for example, di-PPG-2 world-1 adipate, di-PPG-2 ceteth-4 adipate, di-PPG ministerului ester of adipic acid.

Other nonionic surfactants that can be used, obtained by the interaction of carboxylic acids with alkalization or with simple ether polymer, or a monomer, homopolymer or blockcopolymers ethers, or alkoxycarbonyl sorbitane and derivatives alkoxysilanes sorbitan. For example, alkoxysilane, in particular, amoxilonline, sorbitan gives polyalkoxysiloxanes derivatives sorbitan. Esterification polyalkoxysiloxanes sorbitan gives esters sorbitan, such as Polysorbate. For example, polyalkoxysiloxanes sorbitan may be esterified C6-30, preferably C12-22 fatty acids. Examples of such ingredients include Polysorbate 20-85, oleate sorbitan, sesquioleate sorbitan, palmitate sorbitan, sesquiisostearate sorbitan, stearate sorbitan and so on.

D. Structuring agents

It may be desirable to include in the composition one or not�how many structuring agents. Structuring agents to increase the viscosity, and therefore, the structure, composition. Structuring agents may be lipophilic or hydrophilic and form part of an aqueous or non-aqueous phase of the composition. If present, a structuring agent may be in the range of from about 0.1 to 60%, preferably from about 0.5 to 50%, more preferably from about 1 to 45% of the composition.

Desirable structuring agents include silicone elastomers, silicone gums or waxes, natural or synthetic waxes, polyamides, silicone polyamides, and the like.

1. Silicone elastomers

Silicone elastomers include those which are obtained by the reactions of addition-curing in the interaction of SiH-containing diorganotin and organopolysiloxane having terminal olefinic unsaturation, or an alpha-omega diene hydrocarbon, in the presence of a platinum metal catalyst. Such elastomers may also be obtained by other methods reactions such as condensation-curing organopolysiloxane compositions in the presence of ORGANOTIN compounds via the reaction of dehydrogenation between georganopoulos having terminal hydroxyl groups and SiH-containing diorganotin or alpha omega diene; or by condensation from�of eridania organopolysiloxane compositions in the presence of ORGANOTIN compounds or ester titanate using the condensation reaction between georganopoulos, having a terminal hydroxyl group, and a hydrolyzable organosiloxane; peroxide curing organopolysiloxane compositions which thermally cure in the presence organosiloxane catalyst.

One type of elastomer that may be appropriate, is obtained by the reaction of accession curing organopolysiloxane having at least 2 lower alkenyl groups in each molecule, or an alpha-omega diene, and organopolysiloxane with at least 2 associated with silicon atoms of hydrogen in each molecule, and a catalyst of the platinum type. While the lower alkenyl groups such as vinyl, can be in any position in the molecule, the preferred terminal olefinic unsaturation at one or both ends of the molecule. The molecular structure of this component may be straight chain, branched chain, cyclic, or net. Examples of such organopolysiloxanes are methylvinylsiloxane, copolymers of methylvinylsiloxane-dimethylsiloxane, dimethylpolysiloxane with end dimethylpolysiloxane, copolymers of dimethylsiloxane with end dimethylpolysiloxane and methylphenylsiloxane, copolymers of dimethylsiloxane with end dimethylpolysiloxane and diphenylsiloxane and methylvinylsiloxane, copolymers of dimethylsiloxane end� trimethylsilylpropyne and methylvinylsiloxane, copolymers of dimethylsiloxane with end trimethylsilylpropyne and methylphenylsiloxane and methylvinylsiloxane, methyl(3,3,3-cryptochromes)polysiloxane with end dimethylpolysiloxane and copolymers of dimethylsiloxane with end dimethylpolysiloxane and methyl(3,3,3-cryptochromes)siloxane, decadien, octadiene, heptadiene, hexadiene, pentadiene or tetradian or Tridion.

Curing occurs by the reaction of accession associated with silicon atoms of hydrogen to dimethyl metalhydride the siloxane the siloxane or alpha omega diene during the catalysis with the use of the above catalyst. To obtain a structure with a high degree of crosslinking, metalhydride siloxane must contain at least 2 associated with the silicon atom of hydrogen in each molecule to optimize its function as a crosslinking agent.

The catalyst used in the reaction of the accession associated with silicon atoms of hydrogen and alkenyl groups, specifically represented by such examples as chloroplatinic acid, optionally dissolved in alcohol or ketone and this solution optionally aged, complexes of hexachloroplatinic acid with olefins, complexes of hexachloroplatinic acid with alkenylsilanes, complexes of hexachloroplatinic acid with diketones, PLA�both the new black and platinum on a carrier.

Examples of suitable silicone elastomers for use in the compositions according to the invention can be in powder form or dispergirovannykh or solubilizing in solvents, such as volatile or non-volatile silicones or compatible with silicone carriers such as paraffin hydrocarbons or esters. Examples of silicone elastomer powders include the crosslinked polymers vinyldimethyl/Medicon silsesquioxane, such as KSP-100, KSP-101, KSP-102, KSP-103, KSP-104, KSP-105 from Shin-Etsu, hybrid silicone powders that contain peralkaline group such as KSP-200 from Shin-Etsu, which is a fluoro-silicone elastomer, and hybrid silicone powders that contain a phenyl group such as KSP-300 from Shin-Etsu, which is a phenyl-substituted silicone elastomer, and DC 9506 from Dow Corning. Examples of silicone elastomer powders dispersed in compatible with silicone carrier, include crosslinked polymers Dimethicone/vinyldimethyl supplied by different suppliers including Dow Corning Corporation under the trade names 9040 or 9041, GE Silicones under the trade name SPE 839 or Shin-Etsu Silicones under the trade names KSG-15, 16, 18. KSG-15 has a name according to CTFA crosslinked polymer Cyclopentasiloxane/Dimethicone/vinyldimethyl. KSG-18 has the INCI name in accordance crosslinked polymer fenitrothion/Dimethicone/phenylenediamine. �silikonowe elastomers can also be purchased from Grant Indusries under the trademark Gransil. Also suitable are silicone elastomers having long-chain alkyl substitution, such as crosslinked polymers lauryl Dimethicone/vinyldimethyl supplied by Shin-Etsu under the trade names KSG-31, KSG-32, KSG-41, KSG-42, KSG-43 and KSG-44. Stitched organopolysiloxane elastomers, applicable according to the present invention, and methods for their preparation are additionally described in U.S. patent No. 4970252, Sakuta et al., issued November 13, 1990, U.S. patent No. 5760116, Kilgour et al., issued January 2, 1998, U.S. patent No. 5654362, Schulz, Jr. et al., issued August 5, 1997, and Japanese patent application JP 61-18708, the rights to which are transferred to Pola Kasei Kogyo KK, the publications included in this description by reference in its entirety.

2. Silicone gums

Silicone gums are also suitable structuring agents. The term "gum" refers to a silicone polymer having a degree of polymerization sufficient to provide a silicone having a gummy texture. In some cases, a silicone polymer, which forms the gum, can be sewn. Silicone gum typically has a viscosity ranging from about 500,000 to 100 million Centistokes at 25°C, preferably from about 600,000 to 20 million, more preferably from about 600,000 to 12 million FTAs. Everything mentioned in this description ranges include all subranges; for example, 550000, 925000, 3.5 million.

So�e silicone gum can be purchased in pure form from various manufacturers of silicone, including Wacker-Chemie or Dow Corning, and the like. Such silicone gums include gum sold by Wacker-Belsil under trade names SM, Wacker-Belsil 1000 or Wacker-Belsil DM3096. Silicone gum, where X is HE, also known as dimethiconol, available from Dow Corning Corporation under the trade name 1401. The silicone gum can also be acquired in the form of a solution or dispersion in a compatible with silicone medium such as volatile or nonvolatile silicone. A sample of this mixture, having the name according to INCI Dimethicone, can be purchased from Barnet Silicones under the trade name HL-88.

3. Polyamides or silicone polyamides

Also suitable as structuring agents of the oil phase are various types of polymeric compounds such as polyamides or silicone polyamides.

The term "silicone polyamide" means a polymer containing silicone monomers and monomers containing aminogroup, which are described next. Silicone polyamide preferably contains fragments of the General formula:

where X is a linear or branched alkylene, having from about 1 to 30 carbon atoms, each R1, R2, R3and R4independently represents C1-30alkyl with straight or branched chain which may be substituted by one or more hydraulic�cellname groups or halogen atoms; phenyl which may be substituted With one or more1-30alkyl groups, halogen atoms, hydroxyl or alkoxy groups; or a siloxane chain having the General formula:

where Y means:

(a) a linear or branched alkylene, having from about 1 to 40 carbon atoms which may be substituted with (i) one or more aminopropane having the General formula R1CONR1or (ii)5-6cyclic ring, or (iii) phenylene which may be substituted With one or more1-10alkyl groups, or (iv) hydroxy, or (v) With3-8cycloalkane, or (vi)1-20the alkyl which may be substituted by one or more hydroxy groups, or (vii)1-10the alkyl amines, or

(b) TR5R6R7,

where each R5, R6and R7independently represents C1-10linear or branched alkylene, and T is CR8where R8means hydrogen, a trivalent atom N, P, or Al, or C1-30alkyl with a linear or branched chain which may be substituted by one or more hydroxyl groups or groups of halogen; phenyl which may be substituted With one or more1-30alkyl groups, halogen atoms, hydroxyl or alkoxy groups; or a siloxane chain, they�pulling the General formula:

.

Preferably, when R1, R2, R3and R4mean C1-10, preferably methyl, and X and Y represent a linear or branched alkylen. Preferred silicone polyamides having the General formula:

where a and b are independently sufficient to provide a silicone polyamide polymer having a melting point in the range of from about 60 to 120°C and a molecular weight ranging from about 40,000 to 500,000 daltons. One type of silicone polyamide that may be used in the compositions according to the invention, may be purchased from Dow Corning Corporation under the trade name Dow Corning 2-8178 gellant having the CTFA name in accordance copolymer nylon-611/Dimethicone, which is sold in a composition containing PPG-3 ministerului ether.

Also suitable are polyamides, which are from Arizona Chemical under the trade names Uniclear and Sylvaclear. Such polyamides can be terminated with ester groups or amide. Examples of polyamides with terminal ester groups include, but are not limited to, polyamides having the General formula:

where n is the number of amide units such that the number of ester groups ranges from about 10% to 50% of the total number of groups slo�tion of ester and amide; each R1independently represents an alkyl or alkenyl group containing at least 4 carbon atoms; each R2independently represents C4-42hydrocarbon group, provided that at least 50% of the groups R2represent With30-42hydrocarbon; each R3independently represents an organic group containing at least 2 carbon atoms, hydrogen atoms and optionally one or more oxygen atoms or nitrogen; and each R4independently represents a hydrogen atom, C1-10alkyl group or a direct bond with R3or other R4so that the nitrogen atom to which both R3and R4is attached, forms part of a heterocyclic structure, denoted as RA 4N-R3and at least 50% of the groups R4represent a hydrogen atom.

Polyamides with terminal groups of ester and amide, which can be used include polyamides sold by Arizona Chemical under the trade names Sylvaclear A200V or A2614V, both are named according to CTFA Ethylenediamine/hydrogenated dimer delineat copolymer/bis-di-C14-18alkylamide; Sylvaclear AF1900V; Sylvaclear C75V called according to CTFA bis-stearyl Ethylenediamine/neopentylglycol/stearyl hydrogenated dimeric d�linoleic acid copolymer; Sylvaclear PA1200V called according to CTFA polyamide-3; Sylvaclear PE400V; Sylvaclear WF1500V, or Uniclear, such as Uniclear 100VG, having the name according to INCI copolymer of Ethylenediamine/stearyl the dimer delineat, or a copolymer of Ethylenediamine/stearyl the dimer detaliat. Other examples of suitable polyamides include polyamides sold by Henkel under the trademark Versamid (such as Versamid 930, 744, 1655), or Olin Mathieson Chemical Corp. under the trademark Onamid S or Onamid S.

4. Natural or synthetic organic waxes

Also suitable as structuring agents can be one or more natural or synthetic waxes such as animal, vegetable or mineral waxes. Preferably such waxes should have a higher melting temperature, such as from about 60 to 150°C, more preferably from about 65 to 100°C. Examples of such waxes include waxes obtained by Fischer-Tropsch synthesis, such as polyethylene or synthetic wax, or various vegetable waxes such as the wax voskovitsy, candlelike wax, wax, gum acacia, beeswax, ceresin, citylove esters, flower wax, citrus wax, Carnauba wax, jojoba wax, Japan wax, polyethylene, microcrystalline, rice bran, lanolin wax, mink, montany wax, wax palms ouricury, ozokerite, stone fruit, palm wax, PA�Athens, the avocado wax, Apple wax, shellac wax, Clary sage, wax from Barda, grape wax, and derivatives thereof with the pag, such as PEG6-20 beeswax, or PEG-12 Carnauba wax, or fatty acids or fatty alcohols, including their esters, such as hydroxystearic acids (for example, 12-hydroxystearic acid), tristearin, tribehenin, oleic acid, stearic acid and so on.

5. Montmorillonite minerals

One type of structuring agent that may be used includes natural or synthetic montmorillonite minerals such as hectorite, bentonite and their quaternion derivative, which is obtained by the interaction of the minerals with a Quaternary ammonium compound, such as stearalkonium bentonite, hectorite, quaternion hectorite, such as hectorite Quaternium-18, attapulgite, carbonates, such as propylenecarbonate, Antony and the like.

6. The silicas and silicates

To another type of structuring agent that may be used include silica, silicates or silylate silica and derivatives thereof with alkali or alkaline earth metals. Such silicas and silicates are usually found in powdered form and include silica, silylate silica, mixed silicate of magnesium and aluminum, and the like.

�also suitable as structuring agents are various types of polysaccharides, for example, xanthan gum.

E. Sunscreen

It may also be desirable to include in the compositions according to the invention, one or more sunscreens. These include chemical sunscreens block UVA or UVB sunscreen or a physical sunscreen in the form of particles.

Blocking UVA chemical sunscreens

If desirable, the composition may contain one or more blocking UVA sunscreen. The term "blocking UVA" means a chemical compound that blocks UV radiation in the wavelength range from about 320 to 400 nm. Preferred blocking UVA sunscreen are compounds dibenzoylmethane having the General formula:

where R1means H, OR and NRR, where each R independently mean H, C1-20alkyl with straight or branched chain; R2means H or OH; and R3means H, C1-20alkyl with straight or branched chain.

Preferably, when R1means OR; where R is C1-20alkyl with straight or branched chain, preferably methyl; R2means H; and R3mean C1-20alkyl with straight or branched chain, more preferably butyl.

Examples of suitable blocking UVA sances�protective compounds of the indicated General formula include 4-methyldiphenylamine, 2-methyldiphenylamine, 4-isopropylbenzylamine, 4-tert-butylbenzoyl, 2,4-dimethylbenzylamine, 2,5-dimethylbenzylamine, 4,4'-diisopropylethylamine, 4-tert-butyl-4'-methoxydibenzoylmethane, 2-methyl-5-isopropyl-4'-methoxydibenzoylmethane, 2-methyl-5-tert-butyl-4'-methoxydibenzoylmethane and so on. Particularly preferred 4-tert-butyl-4'-methoxydibenzoylmethane, also known as avobenzone. Avobenzone commercially available from Givaudan-Roure under the trademark Parsol 1789 and by Merck & Co. under the trademark Eusolex 9020.

Other types of blocking UVA sunscreens include those derived from decomposition, such as ecamsule, sunscreen, sold under important trade name Mexoryl™, which is tereftalico decompositional having the formula:

.

The composition may contain from about 0.001 to 20%, preferably from 0.005 to 5%, more preferably about 0.005 to 3% by weight of the composition, blocking UVA sunscreen. In a preferred embodiment, the blocking UVA sunscreen is avobenzone, and he is no more than about 3% by weight of the whole composition.

2. Blocking UVB chemical sunscreens

The term "UVB blocking" means a compound that blocks UV radiation in the wavelength range from approx�lo 290 to 320 nm. There are various lockingUVBchemical sunscreens, including alpha-cyano-beta,beta-diphenyl acrylic acid esters, which are disclosed in U.S. patent No. 3215724, which is incorporated into this description by reference in its entirety. One concrete example of alpha-cyano-beta,beta-diphenyl acrylic acid ester is octocrylene, which is 2-ethylhexyl 2-cyano-3,3-diphenylacetate. In some cases, the composition may contain no more than about 110% by weight of the whole composition of octocrylene. Suitable amounts are in the range of about 0.001-10% by mass. Octocrylene can be purchased from BASF under the trade name Uvinul N-539.

Other suitable sunscreens include benzylidene camphor derivatives, which are disclosed in U.S. patent No. 3781417, which is incorporated into this description by reference in its entirety. Such benzylidene camphor derivatives have the General formula:

where R means p-tolyl or styryl, preferably of still. Particularly preferred 4-methylbenzylidene camphor, which is a fat-soluble UVB blocking sunscreen compound, sold by Merck under the trade name Eusolex 6300.

Also suitable are derivatives of cinnamate having the General formula:

where each R and R1independently represents C1-20alkyl with straight or branched chain. Preferably, when R is methyl, and R1represents C1-10alkyl with straight or branched chain, preferably With8alkyl. The preferred compound is the ethylhexyl methoxycinnamate, also known as octoxynol or octyl methoxycinnamate. The connection can be purchased from Givaudan Corporation under the trade name Parsol MCX or from BASF under the trade name Uvinul MC 80. Also suitable are derivatives of mono-, di - and triethanolamines such of methoxy cinnamate, including the DEA methoxycinnamate. Also acceptable is cinoxate, which is an aromatic ethers of the compounds. If present, cinoxate must be in an amount of not more than about 3% by weight of the whole composition.

Also suitable as UVB blocking sunscreen agents are various benzophenone derivatives having the General formula:

where each R-R9independently represents H, HE, NaO3S, SO3H, SO3Na, Cl, R, OR', where R" represents C1-20alkyl with straight or branched chain. Examples of such compounds include benzophenone 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11 and 12. Particularly preferably, when benzophenone derivative� is benzophenone 3 (known as oxybenzone), benzophenone 4 (also called as sulisobenzone), benzophenone 5 (sulisobenzone sodium) and the like. The preferred benzophenone 3.

Also suitable are some salicylate derivative having the General formula:

where each R1, R2, R3and R4independently represents H, OH, NH2or C1-20alkyl with straight or branched chain. Especially preferred is the compound wherein R1, R2and R3represent methyl, and R4represents a hydroxyl or NH2called momenteel salicylate (also known as Homosalate) or mental anthranilate. Homosalate commercially available from Merck under the trade name Eusolex HMS and mental anthranilate commercially available from Haarmann &Reimer under the trade name Heliopan. If there is Homosalate shall be not more than about 15% by weight of the whole composition.

Various amino derivatives of benzoic acid are suitable UVB absorbers, including derivative having the General formula:

where each R1, R2and R3independently represents H, C1-20alkyl with straight or branched chain which may be substituted by one or more hydroxy groups. Particularly preferably, when R1performance�em a N or C 1-8alkyl with straight or branched chain, and R2and R3represent H or C1-8alkyl with straight or branched chain. Especially preferred RAV, ethyl hexyl dimethyl RAWA (Padimate O), metildigoxin RAV and the like. If present, Padimate O shall be not more than about 8% by weight of the whole composition.

Salicylate derivatives are also acceptable UVB absorbers. Such compounds have the General formula: where R represents alkyl with straight or branched chain, including derivatives of the compounds formed with mono-, di - or triethanolamine. Especially preferred are octisalate, tea-salicylate, DEA-salicylate, and mixtures thereof.

Usually the number of the presence of the blocking UVB chemical sunscreens can be in the range of from about 0.001 to 45%, preferably 0.005 to 40%, more preferably 0.01 to 35% by weight of the whole composition.

If desirable, the composition of the invention can be designed to have a specific amount of SPF (sun protection factor), which is in the range from about 1-100, preferably about 10-75 relationships with UVA and UVB in the range of 1-3:1.

F. the film-Forming agents

It may be desirable to introduce into the compositions according to the invention one or more film-forming agents. Film-forming agents usually �would improve the film, formed by cosmetics applied to the skin, and, in some cases, to increase the resistance or the resistance to movement. If present, such film formers may be in the range of from about 0.1 to 50%, preferably from about 0.5 to 40%, more preferably from about 1 to 35% by weight of the whole composition.

Suitable film-forming agents may be silicone-based or organic polymers. Particularly preferred crosslinked siloxane resin, commonly referred to as resin MT or MQ. Examples of such resins include an MQ resin trimethylsulfoxonium or MT resin, known as polymethylsilsesquioxane. Trimethylsulfoxonium can be purchased from Dow Corning under the trade name 749 Fluid, which is a mixture of approximately 50/50 trimethylcyclohexylamine and cyclomethicone, or from General Electric under the trade name SR 1000. Polymethylsilsesquioxane can be purchased from Wacker-Chemie under the trade name resin MK.

The composition may contain other ingredients, including preservatives, plant extracts, vitamins, antioxidants and the like.

V. Method and product

The invention relates to a method of coloring keratin surfaces with the improvement of the appearance of a number of qualitative characteristics, depth or shades of a surface by applying to the skin the composition, the content�ing composite particles, to have a share that contains at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material.

Discovered that if at least part of the feature of the dye present in the composition, replace the composite particles, a colorant applied to the skin, provides a more natural look with depth and a number of qualitative characteristics, allowing at the same time to see through it to the natural shades of skin. The composition may be in the form of the basics of makeup, blush, eyeshadow and the like. Preferably, when about 0.1-90%, preferably 10-90% of the total component of the dye is replaced composite particles, the result will be improved hiding power and an improved appearance.

The invention also relates to a method of reducing sallow, livid or similar to mask the appearance of the cosmetic composition on the skin by applying a composition in which at least a part of a color component is replaced by the composite particles. Typically, when from about 0.1-99%, preferably 10-90% of the total component of the dye is replaced composite particles, sallow, livid or similar to mask the appearance is reduced when applied on the skin.

The invention also Rel�one way to reduce the SKUs in the assortment of shades of color cosmetics and to the resulting range of shades of color cosmetics. The expression "color cosmetic" means a composition applied to the keratin surface, such as skin, hair or nails, for the purpose of imparting color. Examples include Foundation makeup, blush, eyeshadow and the like, and the basis of the most preferred makeup. The term "range of colours" means the range of shades offered manufacturer of cosmetics for one specific SKU color cosmetics. For example, the base makeup "Product X" has a SKU No. 1234, which identifies the product of X and has 25 different colour codes shades designated by two-digit numbers, for example from 01 to 25, i.e. 1234-01 etc. Or in another example, blush "Product Y" identified SKU No. 4567 and has six different coloured shades in the line, codes shades designated by two-digit numbers, for example from 01 to 06.

In the method of the invention, the number of tones in a range of shades for color cosmetics such as Foundation makeup, blush, and the like, can be reduced by 10-80% when using the composite particles for preparing a colored cosmetic composition. In the preparation of cosmetic compositions of the composite particles can be substitute 100% whole component of the dye composition. As a variant, the composite particles can substitute some of the dye component. For example, the decrease of shades reach the preferred�plant embodiment of the invention, when about 30-80%, more preferably from about 40-60% of the total component of the dye is replaced composite particles. Other suitable limits can be from about 1-99%, preferably from about 20-80%, more preferably from about 30-70% by weight of the total component of the dye, replaced by composite particles.

In one embodiment of the method provides a number of shades of Foundation makeup, which shows 10-60% reduction in the number of shades. More specifically, the invention relates to the product line, namely the base makeup, having a source, a number of shades, consisting of 15-30 individual different shades, where the number of tones in a number of shades can be decreased by 0.1 to 99%, preferably about 10-90%, when the basics of makeup is prepared with composite particulates as set forth in this description. In a preferred embodiment of implementation, as an example, the original number of the basics of makeup had 19 shades. When the mixture for the base of the makeup was prepared with the replacement of about 40-60% of the total component of the dye composite particles, it was possible to reduce the number of shades to 11, and still ensure their compliance with all the skin tones in the same shades that were consistent with 19 shades, thus achieved a reduction of 42% in number of shades.

The invention will be further described in connection with the following p�Karami, are for illustration purposes only.

Example 1

Color the mixture was prepared first by mixing 50/50 250 grams of spherical particles of polymethylmethacrylate (PMMA) (Microsphere M-100, Tomen America, or Sepimat P from SEPPIC) and 250 grams of red iron oxide (Unipure Red LC 381EM, Sensient Technologies, South Plainfield, NJ) at room temperature in the container for mixing with CBM on a laboratory scale (Labmaster Model HC-1A, Teledyne Special Equipment, Readco Products, York, PA) having a rotating blade or impeller, which rotates at about 7000 rpm at a speed of tipping set at 35 rpm, and the duration of the process 2 minutes. At room temperature under the fume hood 250 grams of dye were added to a beaker of stainless steel, and diluted with 625 grams of acetone with stirring with propeller stirrer suitable for mixing without splashing. The mixture was allowed to stand in a glass for about 3-5 minutes before formation of a pouring consistency of thick syrup. The contents of the beaker was poured into the pan from Pyrex glass and distributed to a uniform thickness of from about 0.25 to 0.5 inches. The mixture was allowed to dry for 24-36 hours or until then, until the mixture became hard and brittle and devoid of the smell of acetone.

The dry mixture of the dye was removed as a single sheet of glass tray and razrushaya small pieces with hands in gloves to the size, suitable for hammer crusher through the sieve 0.20 inch.

The pieces of the dye mixture was then passed through a hammer mill (Retsch Corporation, Model SR300, Haan Germany) with sieve 0.02 inches, so the pieces are reduced to a particle size suitable for milling in a jet mill (usually about 600 micrometers or less).

Pieces of the mixture of the dye and then subjected to jet milling using a jet mill model 4 supplied Sturtevant. Inc., 348 Circuit Street, Hanover, MA. Air inlet pressure was maintained at 105 psi (724 KPa) and pressure grinding at 100 psi (689 KPa). The feed rate of the material was set at 40 grams per minute. Milling was performed at room temperature for 1 hour. After milling the particle mixture of the dye was collected for drying and spray.

After jet milling particles of the dye mixture was sieved to remove any large particles (e.g., those larger than 45 microns) before drying by spraying, using laboratory vibrating sieving machine model Octagon Ce Digital (Endicotts Limited, Lombard Road, London SW19 England). The mixture particles of the dye, which passed through a sieve of 45 μm, were collected for drying and spray. The mixture particles of the dye, which have not passed through the sieve was discarded.

The mixture particles of the dye, which passed through a sieve, then covered in m�bus for drying spray (Glatt Model GPCG-1 Spray Drying Unit, Glatt Technologies, Inc.). Installation was downloaded from about 500 grams to 1 kilogram of a mixture of particles of the dye. Machine regulated by the following parameters: interval filter vibrator vibration was set at 5 second intervals; valve air vent is installed at 0.4 bar; pressure atomization sputtering was set at 2.5 bar; speed liquid spray flow was set at 25 ml per minute. To 500 grams of the particles of the mixture of the dye was added 94,09 grams of Dow Corning 7-4404 Fluid (a mixture of about 35-45 parts of trisiloxane and about 40-70 parts of Dimethicone silylate), which was dried by spraying on the dye particles in the mix. This gave a powder mixture of from about 7% by weight of the coated particles of the mixture of the dye. After spray drying, the particles were collected and dried overnight in an oven (Cascade TEK Model VO-2) at a temperature of 70-80°C.

The final stage of screening was carried out after drying by spraying, to remove agglomerates. Dried by spraying the coated particles of the mixture of the dye sieved as above, through a sieve of 45 μm. The obtained coated particles of the mixture of the dye were freely flowing and had an average particle size of about 10 microns.

This process was repeated with yellow iron oxide (Unipure Yellow LC 182 EM, Sensient Cosmetic Technologies), black iron oxide (Unipure Black LC 989 EM, Sensient Cosmetic Technoloies) and titanium dioxide (AFDC 200, Kemora Pigments Oy, Finland). The obtained dried in the spray-coated composite particles, yellow iron oxide had a particle size of about 15 micrometers. The obtained dried in the spray-coated black iron oxide dye mixture had a particle size of about 10.6 micrometers; composite particles of red iron oxide about 15 micrometers; and composite particles of titanium dioxide of about 15 micrometers. The composition of the composite particles was:

ColorDyeweight % thermoplastic materialweight % Coatingweight %
whiteTiO246,5PMMA46,5trisiloxane Dimethicone, similat7
redred iron oxides46,5PMMA46,5trisiloxane Dimethicone, similat7
�Erny black iron oxides46,5PMMA46,5trisiloxane Dimethicone, similat7
yellowyellow iron oxides46,5PMMA46,5trisiloxane Dimethicone, similat7

The obtained composite particles used for preparation of compositions of the basics of makeup.

Example 2

Of the base of the makeup were prepared with the following:

ingredientweight %
recipe 1(M)recipe 2
Cyclopentasiloxane/PEG/PPG-18/18 Dimethicone (90:10)5,005,00
sesquioleate sorbitan0,200,20
Cyclopentasiloxane19,6719,67
PEG-10 Dimethicone 3,253,25
lecithin0,0010,001
pentaerythrityl Tetra-di-tert-butyl hydroxyhydrocinnamate0,050,05
titanium dioxide/triethoxycaprylylsilane7,213,61
yellow iron oxides/triethoxycaprylylsilane2,421,21
red iron oxides/triethoxycaprylylsilane0,650,32
black iron oxides/triethoxycaprylylsilane0,220,11
silica/titanium dioxide/Dimethicone0,02-
titanium dioxide-3,63
composite colorant according to the invention (yellow iron oxide/red iron oxides, silica/black iron oxide/PMMA/trisiloxane, Dimethicone, sililar) 14:32:1:71:11-6,87
silica/titanium dioxide/Dimethicone0,02
hydrogenated lecithin0,100,10
silica/methoxyethylamine/silsesquioxane copolymer1,00
titanium dioxide/triethoxycaprylylsilane1,041,04
trimethylsulfoxonium2,502,50
Tocopheryl acetate0,050,05
Cyclopentasiloxane/disteardimonium of hectorite/propylene carbonate (75/20/5)2,25
cyclomethicone/Dimethicone/PEG-10 cross-linked polymer (KSG-24)2,502,50
cyclomethicone/Dimethicone crosslinked polymer3,503,50
Dimethicone/Dimethicone PEG10/15 cross-linked polymer3,503,50
ethylhexylacrylate2,502,50
waterq.s. 100q.s. 100
butyleneglycol3,004,00
sorbic acid0,200,20
Phenoxyethanol/chloroxylenol1,001,00
xanthan gum0,200,20
Laureth-70,250,25
magnesium sulfate1,501,50
hyaluronic acid (1% aqueous solution)2,002,00

The composition was prepared by combining the ingredients of the water phase and oil phase and mixed well prior to emulsification. Received the foundations were emulsions of the type water in oil.

Example 3

Formulation 1 and formulation 2 were tested for 30 participants of the test as follows:

- distribution by age from 18 to 55 years,

users liquid Foundation from a Department store or a prestige brand,

- used basis at least five days a week and

- preferred distribution coverage from full to full-to-medium and natural final finish.

Conducted a five-day unidentifiable cross-sectional study, and in the beginning all participants were acceptance of the test tone. The term "non-identifiable" means that the test participants were not aware of what cosmetic company conducts the test. The term "cross" means that the test participants were divided into two groups of 15. The term "acceptance test tone" means that each of the participants test found the subject a shade of Foundation that it was acceptable. Each group of 15 participants experienced the first of the subjects of the basics of makeup within two days. On day 3 the participants of the tests were returned to the test and received a second test based makeup for the last two days of research.

Participants provided the basis for the makeup of the formulation 1 or formulation 2 in a glass jar labeled "Foundation makeup" and instructed on the fundamentals of applying makeup after their daily regime of skin care and instead of their normal makeup foundations by distributing in the face. Participants in the trials were preduprejdenia, in order not to introduce any new products in your makeup or in the regime of skin care during the period of the test. Participants tested independently filled out a questionnaire after each two-day period, and at the conclusion of the study, they directly asked comparative questions.

Participating in the test were interviewed about what kind of Foundation makeup, formulation 1 or formulation 2, they preferred compared with commonly used basis. The results were as follows:

the comparisonrecipe 1recipe 2 (invention)
the number of participants who liked much/somewhat more/also regularly used as the basis for2322
the number of participants who liked much/somewhat more than regular basis used1012
the number of participants who liked it much more than regular basis used24
the number of participants who liked much/somewhat less than the reg�Jarno basis used 78

Example 4

Eleven more songs the basics of makeup according to the invention were prepared as follows from the composite particles obtained in example 1:

ingredientweight %
deionized waterQS100
Cyclopentasiloxane19,17
Cyclopentasiloxane/PEG/PPG-18/18 Dimethicone5,00
all composite particles**
titanium dioxide/triethoxycaprylylsilaneA 4.24
cyclomethicone/Dimethicone crosslinked polymer3,50
PEG-10 Dimethicone3,25
butyleneglycol3,00
ethylhexyl methoxycinnamate2,50
Cyclopentasiloxane/Dimethicone/PEG-10 cross-linked polymer3,50
dimotiko�/Dimethicone/PEG-10/15 cross-linked polymer 2,50
magnesium sulfate1,50
Cyclopentasiloxane/disteardimonium of hectorite/propylene carbonate1,13
titanium dioxide/triethoxycaprylylsilane1,04
Phenoxyethanol/chloroxylenol1,00
yellow iron oxides/triethoxycaprylylsilane0,85
silica/methoxyethylamine/silsesquioxane copolymer0,50
Laureth-70,25
sesquioleate sorbitan0,20
sorbic acid0,20
xanthan gum0,20
red iron oxides/triethoxycaprylylsilane0,13
hydrogenated lecithin0,10
Tocopheryl acetate0,05
pentaerythrityl Tetra-di-tert-butyl, hydroc�hydrocinnamate 0,05
black iron oxides/triethoxycaprylylsilane0,03
sodium hyaluronate0,02
silica/titanium dioxide/Matikan0,02
Phenoxyethanol0,02

The number of composite particles in % by mass General formulations SG1-11 were as follows:

Composite particles: W = white, B = black, R = red, Y = yellow.

Example 5

A study with 200 participants was conducted to determine provided whether the basis of make-up on the technology according to the invention an improved universal harmonization of shade, enough to fit in with different skin tones in a tonal categories and thus to contribute to the reduction of SKU.

Scored 200 participants in the test. Professional make-up artist chose a line of basics makeup MAC Studio Fix Fluid SPF15 (commercially available), which matched the colour of the skin of each participant in the test. Shades of�Nova MAC Studio Fix were as follows:

Tonal categoryRoom shades MAC Studio Fix Fluid SPF15
lightNC15,NW15
light/mediumNC20, NW20, NC25, NW25, NC30
averageNC35, NC37, NW30, NC40, NC42
medium/darkNC44, NW35, NW40, NW43, NC45
darkNW45, NC50, NW47
deep/darkNW50, NW55, NC55

The list of ingredients in the foundations MAC Studio Fix Fluid SPF15 that were used are the following:

ACTIVE INGREDIENTS: OCTINOXATE 2,50% [] TITANIUM DIOXIDE 1,00%

INGREDIENTS: WATER [] CYCLOPENTASILOXANE [] PEG-10 DIMETHICONE [] BUTYLENEGLYCOL [] TRIMETHYLSULFOXONIUM [] DIMETHICONE [] MAGNESIUM SULFATE [] DIMETHICONE/PEG-10/15 CROSS-LINKED POLYMER [] EXTRACT LAMINARIA SACCARINA [] ALGAE EXTRACT [] TOCOPHERYL ACETATE [] SODIUM HYALURONATE [] TOCOPHERYL ACETATE [] LECITHIN [] HYDROGENATED LECITHIN [] XANTHAN GUM [] SESQUIOLEATE SORBITAN [] METHOXY AMODIMETHICONE/SILSESQUIOXANE COPOLYMER [] LAURETH-7 [] PEG/PPG-18/18 DIMETHICONE [] DISTEARDIMONIUM OF HECTORITE [] SILICA [] DIMETHICONE CROSSLINKED POLYMER [] T�ETHOXYANILINE [] PROPYLENE CARBONATE [] PENTAERYTHRITYL TETRA-DI-TERT-BUTYL HYDROXYHYDROCINNAMATE [] SORBIC ACID [] CHLOROXYLENOL [] PHENOXYETHANOL [] [+/- TITANIUM DIOXIDE (CI 77891) [] IRON OXIDES (CI 77491, CI 77492, CI 77499) [] CHROMOCENE GREEN (CI 77288)]

Shade product Studio Fix, which best correspond to the skin of each participant in the test was selected by a professional artist make-up artist and was used by each participant of the test. And professional make-up artist, and test participants agreed that the applied color to match the skin.

Foundation MAC Studio Fix then removed from the skin of the participant test, and professional make-up artist chose a basis of shades from SG1 to SG11 and applied to each of the trial participants. After applying both, professional make-up artist and participant tests, agreed that inflicted a basis consistent with the skin.

The results showed that the foundations in shades from SG1 to SG11 (11 shades) all match the skin tones, displayed near full tone (19 shades) for products MAC Studio Fix, thus having the result of:

Two shades, SG10 and SG11, the equivalent of three shades of Foundation MAC Studio Fix in a deep dark tonal categories. SG10 match NW50, NW55. SG11 match NW50, NW55, NC55.
Tonal categoryShades of MAC Studio FixAppropriate shades SG (invention)Comments
lightNC15, NW15SG 1The only shade SG1 meet NC15 NW15 and foundations MAC Studio Fix in bright tonal categories.
light mediumNC20, NW20, NC25, NW25, NC30SG2, SG3Two shades, SG2 and SG3, tallied five shades of Foundation MAC Studio Fix in light/medium tonal categories.. SG2 match NC20, NW20, NC25. SG2 consistent with NW25, NC30.
averageNC35, NC37, NW30, NC40, NC42SG4, SG5Two shades, SG4 and SG5, tallied five shades of Foundation MAC Studio Fix in average tonal categories.. SG4 meet NC35, NC37, NW30. SG5 match NC40, NC42.
medium darkNC44, NW35, NW40, NW43, NC45SG6, SG7Two shades, SG6 and SG7, tallied five shades of Foundation MAC Studio Fix in medium/dark tonal categories.. SG6 corresponded to the NC44, NW35, NW40. SG7 match NW43, NC45.
darkNW45, NC50, NW47SG8, SG9Two shades, SG8 and SG9, the equivalent of three shades of Foundation MAC Studio Fix in dark tonal categories, SG8 match NW45, NC50. SG9 match NW45, NW50, NW47..
deep darkNW50, NW55, NC55SG10, SG11

These results are depicted in the attached figure 1 and show that of the base containing the composite particles according to the invention are considerably more versatile in harmonizing shades bases, thus making a contribution to the reduction of SKUs. In particular, it was possible to reduce the number to 11 shades from the source 19 through the use of composite particles according to the invention for the preparation of the composition framework.

Example 6

Composite particles in the form of compressed microspheres were obtained using Expancel 551 DE 20d 60 (DE 20 sets the average particle size of 20 micrometers). About 800 grams was placed in the mixing chamber. Acetone in an amount of about 4000 ml was added at 20 rpm. Received the gel and about 343 g of ultrafine titanium dioxide (DE 50 2 micrometers) was added to the gel. The combination of titanium dioxide and the gel was mixed until homogeneous. The acetone was removed by heating the mixture in a vacuum chamber. Particles of titanium dioxide was involved in the microspheres, and the outer layer of the microspheres was covered from top to about 14 percent by weight silicone polymer, Dow Corning 1107. The final particle size of the microspheres captured with TiO2 was measured using particle size analyzer Malvern, available from Malvern Instrument Scirocco at 200 Worcestershire, UK, and the result was 5-8 micrometers.

Example 7

Composite particles in the form of compressed microspheres get using Expancel 551 DE 20 d 60 (DE 20 sets the average particle size of 20 micrometers). About 800 grams is placed in the mixing chamber. Acetone in an amount of about 4000 ml was added at 20 rpm. Get the gel and about 343 g of ultrafine titanium dioxide (DE 50 2 micrometers) was added to the gel. The combination of red iron oxide and gel are mixed to homogeneity. The acetone is removed by heating the mixture in a vacuum chamber. Particles of red iron oxides are involved in the microspheres, and the outer layer of the microspheres was covered from top to about 14 percent by weight silicone polymer, Dow Corning 1107. The final particle size of the microspheres captured with TiO2measured using a particle size analyzer Malvern, available from Malvern Instrument Scirocco at 200 Worcestershire, UK, and get the result of 5-8 micrometers.

Example 8

1 kg of spherical particles of PMMA (Sepitmat from SEPPIC) and 1 kg of red iron oxide (Unipure Red LC381 EM, Sensient Technologies, South Plainfield, NJ) were placed in anti-static bag Anti-Static Bags, Champion Plastics, 220 Clifton Blvd, Clifton, NJ) and placed in the drum with a capacity of 50 gallons, which was rotated at 68 rpm on a rotating cylinder (Morse, East Syracuse, New York) approx�sideline for 1 hour. The mixture was removed from the drum and placed in a polyphase reactor LittleFord DVT with an internal volume of 5 gallons (LittleFord Day Inc., Florence, KY) and heated to 72°C while mixing at a speed on the ends of the blades of 0.3-0.5 ft/sec. In a separate vessel 1,42 kg of ethanol (anhydrous pure for analysis alcohol 200 - Grad ACS, Sigma Aldrich) was heated to 72°C and was added to the installation LittleFord. Generowanie material was mixed to homogeneity at a speed on the ends of the blades of 0.3-0.5 ft/s. the Ethanol was removed under vacuum and heated to 75°C. the Dry powder was ground in a hammer mill with a sieve 0.01 inches Hosokawa Hammermill 1HP (Hosokawa Col, Osaka, Japan). To 2 kg of non-ferrous mixed particles were added 376,36 grams of Dow Corning 7-44-4 Cosmetic Fluid (a mixture of about 35-45 parts of trisiloxane and about 4-70 parts of Dimethicone silylate) and stirred install LittleFord until smooth.

The system was heat treated at 75°C under vacuum and a stream of nitrogen to dryness. This gave a powder mixture of from about 7% by weight is coated in color of the mixed particles. The final stage of grinding in a hammer mill was carried out after drying to remove agglomerates.

This process was repeated, using yellow iron oxide (Unipure Yellow LC 182 EM, Sensient Cosmetic Technologies), black iron oxide (Unipure Black LC 989 EM, Sensient Cosmetic Technologies) and titanium dioxide (AFDC 200, Kemore Pigments, Oy, Finland). The obtained dried-containing yellow iron oxide particles had a particle size of about 8 m�of Kramerov. The obtained dried, contains black iron oxide coated particles had a particle size of about 8 micrometers. Contains red iron oxide particles had a particle size of about 8 micrometers. Composition of composite particles was as follows:

Color composite particlesUsed dyeThe dye mass % in the composite particlesPMMA mass % in the composite particlesCoating* mass % in the composite particles
whiteTiO246,546,57
redred iron oxide46,546,57
blackblack iron oxide46,546,57
yellowyellow iron oxide46,546,57
*Trisiloxane/Dimethicone, similat

Example 9

The lipstick composition was prepared as follows:

citylove esters
Ingredient%wt./masses.
extract Aloe barbadensis/mineral oil0,50
trimethoxyphenethylamine (PDM 1000)1,00
octyl dodecyl stearoyl stearate3,05
certinaly wax6,50
vaseline32,05
hydrogenated vegetable oil14,00
polybutene0,25
ozokerite16,25
ethylhexyl methoxycinnamate7,50
propyl paraben0,15
fenitrothion1,00
bis-diglyceryl polyacyladipate2,500
q.s.
ethylhexyl salicylate3,50
Tocopheryl acetate0,25
the pigments of example 84,00

The composition is prepared by grinding the pigments in a portion of cetylated esters. Waxes and oils were pooled separately when heated and well stirred. The milled pigment was added to the mixture and well stirred. The mixture was poured into molds and allowed to cool to room temperature.

Example 10

Powder compositions for the age and composition of blush get the following:

Ingredient%wt./masses.
eyeshadowblush
aluminium hydroxide0,003
sesquioleate sorbitan0,001
ascorbyl palmitate0,04
barium sulphate 0,0005
extract of soybeans2,47
WNT0,700,05
lecithinOf 0.0004
candlelike wax5,85
Carnauba waxOf 1.76
castor oilq.s.
polyglyceryl-3 beeswax3,23
simethicone0,05
dipentaerythrityl hexahydrocoumarin2,50
Isodecyl neopentanoate0,05
Caprylic/capric triglyceride9,90
mica4,75
oleyl oleate6,70
octyl palmitate7,00
polybuteneq.s
hydrogenated polyisobutene30,13
dextrin palmitate11,00
ozokeriteOf 2.35
synthetic waxOf 4.95
diisostearate malate8,70
bis-diglyceryl polyacyladipate-21,47
polydecene2,100,35
mica/titanium dioxide0,80
propylparaben0,10
titanium dioxide3,10
Tocopheryl acetate0,04
iron oxides5,11
FD&C blue No. 1 aluminum colorful lacquer0,100,002
D&C red No. 60,01
D&C red No. 7 calcium colorful lacquer0,360,25
odorant0,50
the mixture of the pigments of example 81,001,15

The composition is prepared by grinding the pigments in a portion of the oil. Separately, oils and waxes and United when heated and well stirred. The milled pigment was added. The composition was reduced in cups.

Example 11

Emulsion of the type oil-in-water compositions mascara and eyebrows get the following:

ingredients %wt./masses.
waterq.s.100q.s.100q.s.100
butyleneglycol5,003,003,00
ethylhexyl glycerin0,30
water/acrylates copolymer10,00
polyglyceryl-3 diisostearate, liquid0,50
iron oxides6,003,003,00
the mixture of the pigments of example 86,003,003,00
Kaolin, powder4,003,006,00
polyisobutene6,00
acrylates/octilateral�MFA copolymer 5,00
methyl methacrylate cross-linked polymer, dispersion6,009,00
mica2,00
mica/methylmethacrylate crosslinked polymer3,00
silica1,00
polyquaternium-100,70
Steareth-100/Disteareth-100 IPDI copolymer, viscous liquid1,003,002,25
polyimide-112,00
sodium polystyrene sulfonate (FF polymer6,00
simethicone (liquid)0,100,10
bioseguridad gum (remedy for skin care)0,10
sodium dehydroacetate0,100,100,10
bentonite (thickener)1,251,25
disodium EDTA (preservative)0,100,100,10
hydrogenated castor oil (solid)5,00
Steareth-2 (solid)2,25
Steareth-21 (solid)0,753,503,50
PEG-6 decenteralized-300,50
PEG-40 hydrogenated castor oil (firmly�) 0,50
the sperm oil Ricinus Communic (beaver spring) (liquid)2,00
PEG-20 (solid)2,003,003,00
PVP0,50
PTFE2,00
polyvinyl alcohol (film-forming polymer)3,003,00
nylon-6/silica0,50
water/hydrolyzed wheat protein/PVP cross-linked polymer1,00
water/hydrolyzed wheat protein1,00
water/hydrolyzed phenic�th protein/cystine bis-PG-propyl of silanetriol copolymer (agent for skin care) 7,00
water/polyaminopropyl of biguanid0,200,100,05
water/acrylates copolymer, butyleneglycol/sodium Laureth sulfate5,00
Phenoxyethanol/callington/potassium sorbate/water/hexyleneglycol0,75
Phenoxyethanol0,400,40
Phenoxyethanol/callington/potassium sorbate/water/hexyleneglycol0,85
aminomethyl propandiol0,05

The composition is prepared by combining the ingredients of the water phase and oil phase separately, and then mixing the phases before emulsification and the formation of the mascara composition to the eyelashes and eyebrows.

Although the invention is described in connection with preferred variations�the implementation this should not limit the scope of the invention presents specific form, on the contrary, it should cover such variations, modifications and equivalents that may be included within the essence and scope of the invention defined by the attached claims.

1. Composition for application to keratin surfaces containing composite particles in the form of fused agglomerates having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, where the composite particles contain, by weight of the total composition of a powder material, from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a fraction of a transparent or translucent thermoplastic material.

2. A composition according to claim 1, wherein the colorant is a pigment, a powder, or a mixture thereof.

3. A composition according to claim 2, where the colorant is an organic pigment, an inorganic pigment or mixtures thereof.

4. A composition according to claim 3, wherein the organic pigment is a colorant D&C, dye FD&C or colourful lacquer, and the inorganic pigment is one or more iron oxides, titanium dioxide or zinc oxide.

5. A composition according to claim 2, where the powder is white or uncolored powder material having a particle size in the pre�lah from about 0.001 to 100 micrometers.

6. A composition according to claim 1, wherein thermoplastic material is in the form of a porous solid or hollow spheres.

7. A composition according to claim 1 in the form of Foundation makeup, blush, mascara and eyebrows, eyeshadow, Foundation or lipstick.

8. Composite powdered material in the form of fused agglomerates having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, where the composite particles contain, by weight of the total composition of a powder material, from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of thermoplastic material in the composite particles is in the form of solid or hollow, partial or complete spheres.

9. Powdered material according to claim 8, wherein the transparent or translucent thermoplastic material is of a transparent or translucent hollow or solid spherical particles obtained by polymerizing one or more unsaturated type ethylene monomers.

10. Powdered material according to claim 8, wherein thermoplastic material is in the form of spherical particles which have a refractive index ranging from 1.1 to 1.6 m in volumetric�been able to provide a whitish or grayish appearance.

11. Powdered material according to claim 8, wherein the transparent or translucent thermoplastic material used for producing powdery material is in the form of hollow or solid spherical particles containing polymethyl.

12. A method of coloring keratin surfaces with the improvement of the appearance of a number of qualitative characteristics, depth or shades of a surface by applying to the skin a composition containing composite particles in the form of fused agglomerates having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material.

13. A method according to claim 12, wherein the composite particles in the form of fused agglomerates contain, by mass, from the composite powder material, from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of thermoplastic material in the powder material is in the form of solid or hollow, partial or complete spheres.

14. A method according to claim 12, wherein about 0.1-99% of the total component of the dye present in the composition, comprise composite particles in the form of fused agglomerates.

15. A method according to claim 12, wherein the keratin �overhasty is the skin, and composition gives color and chosen from the basics of makeup or blush.

16. A method of reducing sallow, livid or similar to mask the appearance of the cosmetic composition on the skin by applying a composition containing composite particles in the form of fused agglomerates having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material.

17. A method according to claim 14, where the composite particles have a share that contains at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material.

18. A method according to claim 16, where the composite particles in the form of fused agglomerates contain, by weight of the total composition of a powder material, from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of thermoplastic material is in the form of solid or hollow, partial or complete spheres.

19. A method of reducing the number of SKUs in the assortment of shades of colour cosmetics by preparing a colored cosmetic composition of the composite particles in the form of fused agglomerates having a share containing at least one dye�l, and the proportion containing at least one transparent or translucent thermoplastic material.

20. A method according to claim 19, where the composite particles in the form of fused agglomerates contain from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a fraction of a transparent or translucent thermoplastic material, and where at least some of thermoplastic material is in the form of solid or hollow, partial or complete spheres.

21. A method of obtaining a composite powder material containing fused agglomerates having a share containing at least one dye, and the proportion containing at least one transparent or translucent thermoplastic material, containing stages:
(a) solvation of transparent or translucent thermoplastic material with a solvent;
(b) combining the solvated mixture (a) with one or more pigments;
(c) removing the solvent to form a fused agglomerate.

22. A method according to claim 21, where the transparent or translucent thermoplastic material is in the form of hollow or solid spheres.

23. A method according to claim 21, where the composite particles contain, by weight of the total composition of a powder material, from about 10 to 90 parts in the proportion of the dye and from about 90 to 10 parts of a transparent or share prosjaci�ment of a thermoplastic material, and where at least some amount of thermoplastic material in a powdery composite material is in the form of solid or hollow, partial or complete spheres.



 

Same patents:

FIELD: medicine.

SUBSTANCE: invention refers to dentistry, namely represents an encapsulated oral care composition and an oral care device. According to the invention, the composition contains: (a) a gelatine capsule; and (b) an oral care composition inside the capsule and containing: (i) a hydrophilic active ingredient, (ii) a hydrophobic structuring ingredient, and (iii) an oil carrier. The hydrophilic active ingredient preferentially represents cetylpyridinium chloride. The hydrophobic structuring ingredient preferentially represents gelated mineral oil.

EFFECT: developing the composition according to the invention solves the problem of cetylpyridinium chloride migration and fish-eye capsule defect.

9 cl, 1 ex, 1 tbl

FIELD: chemistry.

SUBSTANCE: claimed invention relates to cosmetic field, namely represents method of colouring or lightening of keratin fibres, which includes stage of mixing without preparation at the moment of application of two compositions (A) and (B) and application of said mixture on said fibres; with said mixture including, at least, 25% of fatty substances relative to the total weight of composition, obtained in mixing two compositions (A)+(B).

EFFECT: method by invention makes it possible to produce intensive and uniform colouring of keratin fibres, with method simultaneously being easy to realise, because mixture in form of oil-reach emulsion does not flow down, but remains on application place, as well as makes it possible to lighten keratin fibres.

19 cl, 3 tbl, 1 ex

Shower gel // 2555358

FIELD: cosmetology.

SUBSTANCE: shower gel comprises lauryl glucoside, sodium carboxylate and lauryl glucoside, coco glucoside, cocon amidopropylbetaine, guar-hydroxypropyltrionium chloride, coco glucoside and glyceryl oleate, ethyl alcohol, a fragrance component, sanguinitrine derived from small-fruited plumepoppy, citric acid and water. The components of the gel are in a certain ratio in wt %.

EFFECT: invention provides high washing and foam-generating capacity with soft action which does not disturb the lipid layer of the skin and has a disinfecting action, without destroying own microflora of human skin.

3 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to liposomal compositions for application in cosmetic industry, including i) from 0.001 to 1 wt % of cyclo-(Arg-Gly-Asp-DPhe-Acha) and/or its salt or solvate, ii) from 0.01 to 20 wt % of one or more lipids; iii) from 60 to 99.99 wt % of one or more physiologically acceptable solvents, as well as to method of their obtaining and application for care and preservation of general condition of skin or hare, for prevention or reduction of wrinkles.

EFFECT: claimed compositions demonstrate favourable properties: improved effectiveness, higher stability, reduced immunogenic reactions in comparison with known properties.

18 cl, 3 dwg, 29 tbl, 18 ex

FIELD: chemistry.

SUBSTANCE: present invention relates to cosmetology and hygiene and provides a foaming detergent composition which contains: a) surfactants consisting of decyl glucoside and coco glucoside, where the decyl glucoside is present in an amount by weight which is 1.8 to 2.2 times the weight of coco glucoside, and b) water, where the amount of decyl glucoside is 10 to 30 wt % of the composition, wherein the composition is free of anionic surfactants.

EFFECT: invention enables to produce a detergent composition having foaming properties in the absence of an anionic surfactant that are equally effective as with a composition with an anionic surfactant.

23 cl, 6 ex

FIELD: cosmetology.

SUBSTANCE: invention is the biological means for cleaning and restoration of skin, comprising pancreatic tissue of pigs or birds, 70% ethyl alcohol, fragrance component, and Ringer's solution, at that the components in the means are in a certain ratio, in wt %.

EFFECT: acceleration of the process of skin regeneration, expanding of range of means having cleaning and skin restoring action.

3 dwg, 1 tbl

FIELD: chemistry.

SUBSTANCE: group of inventions relates to an oral care composition and method of making thereof. An oral care composition comprising a film in an amount of 0.1 wt % to 5.0 wt %, entrained in a carrier, wherein the film comprises a non-ionic surfactant polysorbate 80 in an amount from 10.5 wt % of the film to 20 wt % of the film and a solid calcium peroxide in the amount of 20% to 65% of the film weight. The film may further comprise a therapeutic active in the amount of 0.01 to 30 wt % of the film. The method of making an oral care composition being a dental care product, comprises as follows: (a) providing the carrier; (b) adding lamellar fragments of the film comprising polysorbate, in an amount of from 10.5 wt % of the film to 20 wt % of the film and a solid ingredient comprising calcium peroxide in an amount of from 20 wt % of the film to 65 wt % of the film; and (c) homogenizing the mixture, whereas the film is present in the amount of 0.1 wt % to 5.0 wt % of the of the total weigh of the composition.

EFFECT: higher active material loading in the film formula provides benefits, including reduced amount of film needed in a product, which is at the same time delivering improved efficacy with lower (0,1-5,0 wt %) loading of the film in the dental care composition.

6 cl, 5 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: invention relates to medicine, namely to dentistry, therapeutic-prophylactic preparation for tooth and oral cavity care, and can be applied for prevention and complex treatment of inflammatory diseases of gums, parodentium, stomatitis or elimination of gingival hemorrhage. Therapeutic-prophylactic toothpaste includes glycerin, laurylglycoside, sorbitol, xylite, aerosol, calcium hydrogen phosphate, xanthane resin, sodium benzoate, CO2-extracts of thyme, sage, rosemary, white clay, green clay, red clay and water with specified content of components. For CO2-extracts of thyme, sage and rosemary fulfilled is ratio Wt/Ws/Wr=(0.40-0.50)/(0.25-0.35)/0.20-0.25), where Wt, Ws, Wr are weight parts of respectively CO2-extracts of thyme, sage and rosemary, with particles of green, white and red loam having sizes in interval 0.1-100 mcm and being obtained from clay, dried at 80-400°C.

EFFECT: technical result consists in increased efficiency of prevention and treatment of inflammatory diseases of oral cavity, parodentium, in particular gingivitis, periodontitis, as well as increase of cleaning ability of toothpaste with simultaneous reduction of abrasive influence on tooth enamel; and technical result consists in extension of arsenal or toothpastes of complex action, which render healing and preventive action on organs and tissues of oral cavity.

9 cl

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to oral care agents. What is presented is using an oral care composition in the form of a mouthwash containing a fluoride ion source and a ternary polymer system consisting of xanthane gum, carboxymethyl cellulose and copovidone for dental erosion and/or wear control. This composition is also effective in dental caries control.

EFFECT: using fluoride ions in a combination with the ternary polymer system provides the better protection of the dental surface against dental erosion as compared to using fluoride ion only.

7 cl, 4 dwg, 5 ex

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to the chemical-pharmaceutical industry and represents an agent for preventing or reducing pigmentation, containing a compound presented by the following formula (1) its stereoisomer and/or its pharmacologically acceptable salt, wherein: R1 represents a hydrogen atom or an alkyl group with a linear or branched chain having 1-4 carbon atoms; R2 represents a hydrogen atom or an unsubstituted aliphatic hydrocarbon group having 1-4 carbon atoms; R3 represents an unsubstituted aromatic group having 5-15 carbon atoms, substituted by an alkyl group having 1-6 carbon atoms, by an alkoxy group containing an alkyl chain having 1-6 carbon atoms, or by a phenyl group; R3 also represents an aromatic group having 5-15 carbon atoms; n is equal to 1 or 2, and m represents an integer falling within 0 to 3.

EFFECT: preparing the agent for preventing or reducing pigmentation.

10 cl, 10 ex, 6 tbl

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine and is intended for oral cavity care. Compositions contain: a) guanidine-based active substance, b) film-forming polymer, c) hydrophobic modifier of viscosity in quantity, sufficient for provision of composition for oral cavity care with time particle sedimentation more than 20 minutes, and d) oil carrier. Guanidine-based active substance preferably represents L-arginine. Film-forming polymer preferably represented GANTREZ. Hydrophobic modifier of viscosity preferably represents thickened mineral oil. Oil carrier preferably represents natural oil. Composition is enclosed in gelatine capsule. Method of teeth cleaning includes application on teeth of composition for oral cavity care in such a way that composition for oral cavity care cleans teeth. Device for oral cavity care, which contains: handle, fastened on handle head, where head has external surface and a row of teeth-cleaning elements, projecting outwards on external surface, and gelatine capsule, which contains composition for oral cavity care, located on head.

EFFECT: group of inventions makes it possible to increase teeth cleaning efficiency.

14 cl, 2 ex, 1 tbl

FIELD: chemistry.

SUBSTANCE: invention relates to the encapsulation of active ingredients and to processing textile materials. Claimed are: a method of processing textile materials, containing microcapsules of active ingredients, fibres and/or textile materials, obtained from the said method, and their cosmetic or pharmaceutical application and/or their application as a repellent.

EFFECT: claimed invention makes it possible to increase the active ingredient stability for an acceptable number of washings.

16 cl, 6 dwg

FIELD: chemistry.

SUBSTANCE: invention relates to application of composition, which contains Polygonum aviculare grass 20-25 wt %, cowberry leaves 13-17 wt %, Viburnum sargentii koehne fruits 5-9 wt %, fruits of dog-rose of different of Far-East species 20-25 wt %, Schisandra chinensis seeds 13-17 wt %, Fragaria orientalis leaves 5-9 wt % and corn stigmas 5-9 wt %, as means with oil protective activity in treatment of glomerulonephritis.

EFFECT: invention provides positive influence on basic indices of glomerulonephritis: promotes recovery of diuresis, reduction of proteinuria, reduction of azotemia, cryoglobulinemia and level of circulating immune complexes.

2 tbl

FIELD: medicine.

SUBSTANCE: integrated therapy additionally involves administering thin-walled Capsicum annuum powder of the type paprika in a dose of 30 g with the specified selenium contents of 1 mg/kg and a capsule of alpha-tocopherol acetate in a dose of 100 mg manufactured by Lyumi, LLC (Ekaterinburg) orally during meals 3 times a day. The length of the treatment is 20 days.

EFFECT: invention enables reducing the time of the treatment, increasing its efficacy, and prolonging remission.

1 tbl, 2 dwg, 2 ex

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. Described is a wet product from a non-woven material, soaked with a substance for personal hygiene, which is applied in household or for local processing for medicinal purposes. The non-woven material represents a bonded fibrous cloth, possessing hydrophilic properties, or a fibrous cloth, to which hydrophilic properties have been applied by processing with moisturising additives.

EFFECT: wet product possesses the high absorbing property and increased ability of releasing a substance, possessing the absorbing ability, and its transfer onto the surface.

21 cl, 3 tbl

FIELD: medicine.

SUBSTANCE: invention refers to dentistry, namely represents an encapsulated oral care composition and an oral care device. According to the invention, the composition contains: (a) a gelatine capsule; and (b) an oral care composition inside the capsule and containing: (i) a hydrophilic active ingredient, (ii) a hydrophobic structuring ingredient, and (iii) an oil carrier. The hydrophilic active ingredient preferentially represents cetylpyridinium chloride. The hydrophobic structuring ingredient preferentially represents gelated mineral oil.

EFFECT: developing the composition according to the invention solves the problem of cetylpyridinium chloride migration and fish-eye capsule defect.

9 cl, 1 ex, 1 tbl

FIELD: chemistry.

SUBSTANCE: claimed invention relates to cosmetic field, namely represents method of colouring or lightening of keratin fibres, which includes stage of mixing without preparation at the moment of application of two compositions (A) and (B) and application of said mixture on said fibres; with said mixture including, at least, 25% of fatty substances relative to the total weight of composition, obtained in mixing two compositions (A)+(B).

EFFECT: method by invention makes it possible to produce intensive and uniform colouring of keratin fibres, with method simultaneously being easy to realise, because mixture in form of oil-reach emulsion does not flow down, but remains on application place, as well as makes it possible to lighten keratin fibres.

19 cl, 3 tbl, 1 ex

Shower gel // 2555358

FIELD: cosmetology.

SUBSTANCE: shower gel comprises lauryl glucoside, sodium carboxylate and lauryl glucoside, coco glucoside, cocon amidopropylbetaine, guar-hydroxypropyltrionium chloride, coco glucoside and glyceryl oleate, ethyl alcohol, a fragrance component, sanguinitrine derived from small-fruited plumepoppy, citric acid and water. The components of the gel are in a certain ratio in wt %.

EFFECT: invention provides high washing and foam-generating capacity with soft action which does not disturb the lipid layer of the skin and has a disinfecting action, without destroying own microflora of human skin.

3 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: group of inventions relates to liposomal compositions for application in cosmetic industry, including i) from 0.001 to 1 wt % of cyclo-(Arg-Gly-Asp-DPhe-Acha) and/or its salt or solvate, ii) from 0.01 to 20 wt % of one or more lipids; iii) from 60 to 99.99 wt % of one or more physiologically acceptable solvents, as well as to method of their obtaining and application for care and preservation of general condition of skin or hare, for prevention or reduction of wrinkles.

EFFECT: claimed compositions demonstrate favourable properties: improved effectiveness, higher stability, reduced immunogenic reactions in comparison with known properties.

18 cl, 3 dwg, 29 tbl, 18 ex

FIELD: chemistry.

SUBSTANCE: present invention relates to cosmetology and hygiene and provides a foaming detergent composition which contains: a) surfactants consisting of decyl glucoside and coco glucoside, where the decyl glucoside is present in an amount by weight which is 1.8 to 2.2 times the weight of coco glucoside, and b) water, where the amount of decyl glucoside is 10 to 30 wt % of the composition, wherein the composition is free of anionic surfactants.

EFFECT: invention enables to produce a detergent composition having foaming properties in the absence of an anionic surfactant that are equally effective as with a composition with an anionic surfactant.

23 cl, 6 ex

FIELD: medicine, oncology, amino acids.

SUBSTANCE: invention relates, in particular, to the development of an antitumor preparation based on natural substances. Invention relates to an amino acid preparation comprising at least one modified essential amino acid obtained by treatment of amino acid by ultraviolet radiation (UV) at wavelength 250-350 nm for 12-80 h at temperature 15-30oC or with ozone at temperature 15-25oC. The modified amino acid has no toxicity for health cells. Also, invention relates to a method for preparing such preparation. Invention provides the development of an antitumor preparation based on modified amino acids and expanded assortment of antitumor preparations being without cytotoxicity for normal cells.

EFFECT: valuable medicinal antitumor properties of preparation.

8 cl, 4 tbl, 2 dwg, 4 ex

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