System and method of synchronising device for patient monitoring with central server

FIELD: medicine.

SUBSTANCE: invention relates to devices for medical monitoring. The method contains stages at which: a packet (7) of data about a patient is transmitted from a device (10) for patient monitoring to the central server (12); a message (72) with acknowledgement (ACK), transmitted by the central server (12) in response to receiving by the central server (10) of the transmitted packet (70) of data about the patient, with a message with acknowledgement containing a time stamp, provided from the central server (12) clock (46), indicating the time and date, when the central server (12) received the packet (70) of the patient's data; the message time stamp (72) with ACK is compared with the current time of the clock (28) of the patient monitoring device (10); and if the difference between the current time of the clock (28) of the patient monitoring device (10) and the time stamp (74) with ACK is larger than the first preliminarily determined time, the clock (28) is synchronised in accordance with the time and date in the time stamp (74) in the message (72) with ACK.

EFFECT: provision of control of the time synchronisation interface.

13 cl, 5 dwg

 

The present application relates to medical monitoring devices and clinical information to devices for monitoring the physiological state of the patient. It finds particular application in synchronization of date and time monitors patients with a Central server and is described specifically in this regard.

Currently, with the increasing demand on centralized electronic patient records, patient records and data are often sent to a centralized server. Typically, the device for monitoring a patient who create patient records and data, contain clock with battery power. At the time of creation of records and data, record or data file includes a time stamp indicating the date and/or time of creation of the record or file. Often watch the patient monitors remain for long periods of time without recalibration. There is nothing unusual in the fact that the clock is ahead or behind by five minutes or more for a period in a month or so. Incorrect timestamps can change the apparent temporal sequence of data entry into the system of multiple devices. Errors in the visible sequence or temporal coordination of events can lead to Clinician patients misdiagnosis or delay in treatment of patients.

Typically, in �ospitale use the server network time Protocol (NTP/SNTP) to synchronize the clock of a Central server with the standardised time. One drawback of using server NTP/SNTP devices patient monitoring is that the monitoring devices need a connection to the server NTP/SNTP. The connection with the server NTP/SNTP cannot be performed using a serial/RS232 connection. Another disadvantage associated with the use of server NTP/SNTP, is that a temporary agreement with the synchronization will not be managed by the device for monitoring the patient. In some cases, the measurement of patient monitors can be affected if the server NTP/SNTP tries to synchronize the monitoring device simultaneously with the execution of the measurements.

In the present application provided a new and improved method of synchronization of date and time monitors patients with a Central server, which overcomes the above problems and more.

In accordance with one aspect provides a method of synchronization of the device for patient monitoring. The packet data of the patient transfer device with the patient monitor to the server. In response to receiving the server transmitted packet data on the patient monitoring device of a patient receive from the server a confirmation message (ACK). Watch the device for monitoring the patient synchronize in accordance with the timestamp in the ACK message.

In accordance� with another aspect provided by the device monitoring the patient. The plurality of sensors collects physiological data from the patient. The controller transmits the packet data of the patient generated from the collected physiological data to the server and receives a confirmation message (ACK) from the server in response to receiving a data packet on the patient. The synchronization unit synchronizes the clock of the patient monitor with the timestamp in the ACK message.

In accordance with another aspect provided by the patient monitoring system. The plurality of sensors collects physiological data from the patient. The server sends a confirmation message (ACK) in response to receiving the packet data of the patient, wherein the ACK message contains a timestamp. The controller transmits the packet data of the patient generated by the collected physiological data to the server and receives the ACK message from the server in response to receiving a data packet on the patient. The synchronization unit synchronizes the clock of the patient monitor with a timestamp of the ACK message.

One advantage is improved efficiency and quality of patient care.

Another advantage is a simpler and more reliable synchronization of patient monitors with a single time.

Another advantage is the management of temporary approval of the synchronization.

Specialists in this field will appreciate, other additional�Uo advantages of the present invention after reading and understanding the following detailed description.

The invention may be implemented in various components and arrangements of components and various steps and sequences of steps. The drawings are intended only for the purpose of illustration preferred embodiments and should not be interpreted as limitations of the invention.

Fig. 1 shows a schematic illustration of a system for monitoring a patient in accordance with the present application.

Fig. 2 shows a schematic illustration of the relationship of the device for patient monitoring/Central server.

Fig. 3 illustrates the example device interface of monitoring a patient in accordance with the present application.

Fig. 4 shows a block diagram of the sequence of operations of the controller device monitoring of the patient.

Fig. 5 presents a block diagram of the sequence of operations, monitoring the patient in accordance with the present application.

As shown in Fig. 1, a variety of monitors 10 patients transmit packets of patient data to the Central server 12. Monitors 10 patients, for example, may represent a bedside patient monitor, monitor, which moves together with the patient, such as a transmitter wearable ambulatory patient monitoring systems or Monitors etc. 10 patients may have a more permanent attachment, such ka� have a wall mounted monitor, which is permanently associated with each bed or chamber. Monitors 10 patients have one or more sensors 16 that measure physiological parameters of a patient and generate physiological data reflecting them. These sensors 16 include ECG sensors, intravenous fluid pumps, blood pressure sensors, sensors SpO2, pulse sensors, thermometers, sensors, respiratory sensors, exhaled gas, etc. of Course, other sensors 16 may be associated with monitors 10 patients, and not all of these sensors 16 should be associated with a patient at any given time. As used herein, the sensors 16 indicate the data sources that reflect the patient's condition.

The sensors 16 transmit physiological data generated via connected to the body network, Bluetooth, or the like on the controller 18 corresponding monitor 10 of the patient. Monitors 10 patients put a time stamp on the received data, and temporarily saves the data with the time stamp in the memory 20. The controller 18 corresponding monitor 10 patient organizes patient data into packets. The controller 18 transmits the generated data packets on the patients to the Central server 12 via a wireless network, a wired network, a combination of wired and wireless networks or the like, and receives a confirmation message (ACK) from the Central serv�and 12, which confirms receipt of the data packets for the patients.

The controller 18 also manage the displays 22 monitors 10 patients to the measured physiological data received from each of the sensors 16 in the respective display 22 of the patient monitor. Monitors 10 patients also contain an input device 24, which enables a user, such as a system administrator, to view, manipulate and/or interact with the data displayed on the display 22. The input device 24 can be a separate component or built into the display 22, for example in the monitor touch screen.

The controller 18 also includes a processor, e.g. a microprocessor, being configured to execution of the software monitoring the patient for operations, described in more detail below, the synchronization software on time. Typically, the software monitoring of the patient is stored in or written to a different physical memory or computer-readable media 20 information for execution by the processor. Types of computer-readable media 20 information include memory such as a hard disk drive, CD-ROM, DVD-ROM etc. is Also provided for other implementations of the processor. The display controllers, specialized integrated circuits (ASIC) and details�Lera are illustrative examples of components of other types, that can be implemented to provide the functions of the processor. Implementation options can be implemented using software for execution by a processor, hardware or some combination thereof.

The monitor 10 of the patient includes a clock 28 controlled by the controller 18. Battery 30 powers your watch, a controller and other components of the monitor 10 of the patient. Watch 28 give the controller time and date to be used for setting timestamps on the data about the patient. The controller 18 also controls the clock synchronization 28 of the monitor 10 of the patient with the Central server 12 or the server 34 time. In one embodiment of the monitor 10, the patient sends packets of data on patients with timestamps to the Central server 12. In response to receiving packets of data on patients Central server 12 transmits the ACK message to the monitor 10 of the patient. The controller 18 may transmit and receive information, bogus packages patient, packages patient data, ACK messages to or from a Central server 12 and the server 34 time using means of communication which includes RS232, HL&LAN, NTP, SNTP, etc. the ACK message contains a timestamp that indicates the time and date when the Central server 12 received the appropriate verified data package. Con�Rollerball compares the time stamp of the ACK message with the current time 28 hours monitor 10 of the patient, to determine the need for clock synchronization 28 patient monitor, for example, if the clock 28 of the patient monitor and the timestamp of the ACK message are different, for example, more than 5 seconds. In another embodiment of the monitor 10, the patient sends dummy data packets to the Central server 12 or the server 34 time periodically to cause the return of the ACK messages for clock synchronization 28 patient monitor with Central servers. The monitor 10 of the patient preferably transmits dummy packets when the patient monitor is enabled or in a pre-determined time intervals, for example every hour. In response to receiving the dummy data packets to the Central server 12 or the server 34 time transmits the ACK message to the monitor 10 of the patient, which contains a time stamp of the Central server 12 or the server 28 time. Then the time on the clock 28 of the monitor 10 of the patient is compared with a time stamp for synchronization purposes of the monitor 10 of the patient. To during synchronization to prevent the influence of the operation of the monitor 10 of the patient, the controller 18 delays the clock synchronization 28 patient monitor as long as any operation performed is completed. For example, if you open the patient's record, the controller 18 delays the sync as long as the patient's record will not be Zach�it; if you do the measurement of the patient, the controller 18 delays the synchronization until then, until the measurement is completed will not receive a time stamp and will not be included in the record; when the print ribbon of the patient monitor 10 of the patient, the controller 18 delays up until the printing is completed, etc.

In some cases, the unit 32 controls the synchronization clock synchronization 28 patient monitor with Central server 12 or the server 34 time. For example, the unit 30 checks the synchronization time of the monitor 10 of the patient relative to the timestamp of ACK messages transmitted from the Central server 12 or the server 34 time. If the difference between the clock of the monitor 10 of the patient and the time stamp from the Central server 12 or the server 34 time exceeds a predetermined amount of time, for example 5 seconds, the unit 30 synchronization synchronizes the clocks of 28 patient monitor with time stamp Central server 12 or the server 34 time. Unit 30, the synchronization may include a suitable programmed computer or processor, the software used by the controller or processor etc.

Channels of communication between monitors 10 patients and the Central station 12 and the server 34 time can be wireless. If the monitor 10 of the patient carried out, for example, the local monitor, wearable or mounted on the rack for intravenous infusion, the patient can leave the close proximity, taking the monitor 10 patient with me. Wireless communication between monitors 10 patients and the Central station 12 and the server 34 time provides the patient with greater mobility, while maintaining the ability to transmit data packets on the patients. If the monitor 10 of the patient is implemented with a more permanent attachment, the channels of communication between monitors 10 patients and the Central station 12 and the server 34 can be straight lines connections, such as standard Ethernet cables.

The Central server 12 receives packets of data on patients from multiple monitors 10 patients. The Central server 12 are often placed centrally in relation to monitors 10 patients, for example, the Central server database for patients at a health center or clinic, hospital, health network or etc. Monitors 10 patients transmit packets of data about patients to the controller 36 of the Central server 12. In response to receiving packets of data about the patient, the controller 36 generates the ACK message. The controller 36 transmits the generated ACK message to the monitor 10 of the patient, who handed over the packet data of the patient. The controller 36 may transmit and receive information, a dummy packets �of atianta, packages patient data, ACK message, the rejection message or the like on the monitors 10 patients through a means of communication including RS232, HL&LAN, NTP, SNTP, etc. the Central server 12 also provides memory storage 38 for packets of data on patients, and other patient information received from the monitor 10 patients. Typically, the data is sorted by patient, but they can also be indexed according to diagnosis, treatment, etc., to facilitate the retrieval of data.

The controller 36 of the Central server 12 also controls the display 40, the Central server 12 to display the patient information received from the monitor 10 patients. The Central server 12 also comprises a device 42 input that allows the user, such as a system administrator, to view, manipulate and/or interact with the data displayed on the display 40 or manually sync specific monitor 10 of the patient or the Central server 12. The device 42 of the input may be a separate component or integrated into the display 30, for example a monitor with a sensitive screen. Clinicians can also remotely access the memory to create reports, diagnoses, analysis of the best methods of treatment, etc.

The controller also includes a processor 44, for example a microprocessor, which�made with the ability to execute software for processing, the storage and retrieval of patient data for operations that are described in more detail below, and, optionally, the synchronization software on time. Typically, the control software stored in a memory or computer-readable media 38 information and perform a CPU 44. Types of computer-readable media 38 information include memory such as a hard disk drive, CD-ROM, DVD-ROM etc. is Also provided for other implementations of the processor 44. The display controllers, specialized integrated circuits (ASICs) and microcontrollers are illustrative examples of components of other types that can be implemented to provide the functions of the processor 38. Implementation options can be implemented using software for execution by a processor, hardware or some combination thereof.

Watch 46 is also included in the Central server 12 and are under the control of the controller 36. Watch 46 watching time and date Central server. Watch 46 also give the time and date of the Central server 12 for timestamp in ACK messages generated by the controller 36 Central server. In some cases, the controller 36 controls the clock synchronization 46 Central server 12 to server 34 time. In some cases, block 48, the synchronization control�possessing a clock synchronization 46 Central server to server 34 time. The synchronization block 48 may include a suitable programmed computer or processor, the software used by the CPU, or etc.

The server 34 time stores for the hospital reference time of the reference clock 50. The server 34 time, such as a Central time server or etc., often is located centrally relative to a Central server 12 and monitors patients 14. Reference clock 50 reference monitor time and date of the hospital. Reference clock 50 in one embodiment of the implementation are supported by the government standard national or global reference clock, used computers, researchers, etc. In another embodiment of the reference clock 50 synchronizes with the national or global reference clock, using NTP or SNTP.

In one embodiment, the implementation of the server 34 time receives a dummy or real data packets from the plurality of monitors 10 patients. In response to receiving data packets, the controller 52 generates an ACK message with a time stamp indicating the reference date and time tracked by the clock 50. The controller 52 transmits the generated ACK message to the monitor 10 of the patient, who handed over the packet data of the patient. The controller 52 may transmit and receive information, a dummy packet patient reported ACK�I to the Central server 12 and 10 monitors patients through a means of communication including RS232, HL&LAN, NTP, SNTP, etc.

The controller 52 of the server 34 also controls the display 54 server 34 time to display time information of the hospital. The server 34 also comprises a device 56 input that allows the user, such as a system administrator, to view, manipulate and/or interact with the data displayed on the display 54, or manually synchronize specific monitor 10 of the patient or the Central server 12. The device 56 of the input may be a separate component or integrated into the display 54, such as a monitor touch screen.

The controller also includes a processor 58, such as a microprocessor, which is made with the possibility of execution of the software maintenance time and synchronization.

As illustrated in Fig. 2, the monitor 10 of the patient transmits the packet 70 of patient data to the Central server 12. In response to receiving packets 70 of patient data from the monitor 10 of the patient, the Central server 12 transmits the ACK message 72 to the transmit monitor 10 of the patient, informing the monitor 10 of the patient that the package 70 of patient data received by the Central server 12. The ACK message contains 72 74 mark time, containing a sequence of symbols indicating the time and date of the Central server 12. In one of VA�of Ianto the implementation of the ACK message 72 send, even if the packet data of the patient rejected the Central server 12. In another embodiment, monitors the implementation of the 10 patients synchronize by sending bogus packets 70 data to the Central server 12 or the server 34 time. In response to receiving the dummy data packets to the Central server 12 or 34 time server transmits the ACK message 72 that includes a mark of 74 time indicating the time and date of the Central server 12 or the server 34 time.

Fig. 3 shows the display 22 of the monitor 10 of the patient. Physiological data and patient information associated with a patient monitor, the display on the display 22. The display 22 can display subdisplay 80 patient ID, subdisplay 82 ECG, subdisplay 84 SpO2subdisplay 86 heart rate, etc. the Monitor 10 of the patient comprises a device for issuing an alarm to show, than change the time on the monitor 10 pre-defined number, for example, the patient monitor differs for 30 seconds. In that case, if the time change of the monitor 10 of the patient exceeds a predetermined number, the activation of the device issuing the alarm to alert maintenance and medical personnel that the monitor 10, the patient may face the problem of temporary approval. The device issuing the alarm includes a speaker sound�type alarm or means 88 visual signaling for example the line synchronization, added to the records of the patient and on subdisplay to show the potential problem associated with the temporary coordination of patient data. In another embodiment, the implementation of line 88 synchronization are added to the patient record and on subdisplay in each case, synchronization or adjustment of time that is longer than a predefined length of time.

In one embodiment, the implementation of the UI or drop-down menu 90 on the display 22 of the monitor 10 of the patient allows the system administrator to identify specific aspects of the synchronization of the monitor 10 of the patient. Interface or menu 90 allows the system administrator to manually synchronize 92 time and date of the monitor 10 of the patient. Interface or menu 90 also allows the system administrator to adjust, 94 synchronization, through which the monitor 10 of the patient periodically transmits dummy data packet to ensure the accuracy of the time and date of the monitor 10 of the patient. In one embodiment, the implementation of all monitors 10 patients send dummy data packets simultaneously to the Central server 12 or the server 34 time. In another embodiment, monitors the implementation of the 10 patients send dummy data packets at different points in time during the hour to avoid overloading the Central server 2. In another embodiment of the dummy packets are sent only when the time since last data transmission exceeds a pre-defined condition. Along with time, 94 synchronization, you can also specify the location 96, which sends bogus data package to avoid overloading the Central server 12 dummy data packets. In one embodiment, the implementation of dummy data packets sent to the Central server 12. In another embodiment of the dummy data packets sent to the server 34 time. The tool 98 alarm or warning is additionally provided in order to show if the change exceeds the time monitor 10 of the patient a predetermined number, which may also determine the system administrator. Interface or menu 90 also allows the system administrator to adjust the amount of time between 100 28 hours of patient monitor and the timestamp required for synchronization of the monitor 10 of the patient.

As shown in Fig. 4, is illustrated a block diagram of the sequence of operations of the controller device monitoring of the patient. In step 110 patient data is passed from the patient monitor to the Central server. In step 112 from the Central server receives the ACK message via the patient monitor in response to receiving Yes�tion about the patient. In step 114 the clock of the patient monitor is compared with the timestamp of the ACK message. In step 116 determines are rejected if the clock of the patient monitor for more than the first predetermined number from the timestamp of ACK messages. In response to the deviation of the clock of the patient monitor for more than the first predetermined amount of time from the timestamp of ACK message in step 118 determines whether exceeds the difference between the clock of the patient monitor and the timestamp of the ACK message, the second predetermined number. If the difference between the clock of the patient monitor and the timestamp of the ACK message does not exceed a second predefined value, in step 120 hours of patient monitor synchronizes with the time stamp of the ACK message. If the difference between the clock of the patient monitor and the timestamp of the ACK message exceeds a second predefined value, in step 122, the patient monitor will synchronize with the time stamp of the ACK message, in step 124 to write the patient note a discrepancy of time and warning, and in step 126 sends an error message to the appropriate personnel.

As shown in Fig. 5, is illustrated a block diagram of the sequence of operations of the monitoring system of the patient. In step 140 determines whether the clock of the patient monitor are synchronized at t�within a third predetermined amount of time since the last check synchronization. If the clock has not been synchronized within the third predetermined time, in step 142 a fictitious patient data is passed from the patient monitor to the Central server or time server. In step 144, the patient monitor receives the ACK message from the Central server or time server in response to receiving the patient's data. In step 146 the clock of the patient monitor is compared with the timestamp of the ACK message. In step 148 determines are rejected if the clock of the patient monitor for more than the first predetermined number from the timestamp of ACK messages. In response to the deviation of the clock of the patient monitor for more than the first predetermined amount of time from the timestamp of ACK message in step 150 determines whether exceeds the difference between the clock of the patient monitor and the timestamp of the ACK message, the second predetermined number. If the difference between the clock of the patient monitor and the timestamp of the ACK message does not exceed a second predefined value, in step 152 the clock of the patient monitor synchronizes with the time stamp of the ACK message. If the difference between the clock of the patient monitor and the timestamp of the ACK message exceeds a second pre-determined value, in step 154, the patient monitor will synchronize with the time stamp of the ACK soo�absorption, time discrepancy, in step 156 note the warning on the record of the patient and in step 158 sends an error message to the appropriate personnel.

The invention is described in relation to preferred embodiments. Modifications and changes may come to mind after reading and understanding the preceding detailed description. It is understood that the invention includes all such modifications and changes to such extent that they are included in the scope of the applied claims of the invention or its equivalents.

1. Time synchronization (28) of the device (10) patient monitoring clock (46) Central server (12), wherein the method contains the stages at which:
transfer the package (70) of patient data from the device (10) monitoring the patient to the Central server (12);
get on the device (10) patient monitoring message (72) with acknowledgement (ACK) transmitted by the Central server (12) in response to receiving by the Central server (10) transmitted packets (70) of patient data, wherein the confirmation message contains a time stamp provided from the clock (46) Central server (12), indicating the time and date when the Central server (12) received packet (70) patient data;
compare the timestamp of the message (72) with ASA with the current clock time (28) of the device (10) monitoring the patient; and
if the difference between� the current clock time (28) of the device (10) monitoring of the patient and the mark (74) time of message (72) with ASA more than the first predetermined time, synchronize the clock (28) in accordance with time and date stamp (74) of the time in the message (72) with ASA.

2. A method according to claim 1, additionally containing a stage, on which:
generate a warning (88) on the synchronization in response to synchronization of changing the clock time (28) more than the second predetermined time.

3. A method according to claim 1, additionally containing a stage, on which:
transfer the package (70) of dummy data to the Central server (12) in response to the lack of clock synchronization (28) of the device (10) for monitoring a patient that has not been synchronized within the third predetermined time since the last execution stage of the comparison.

4. A method according to any one of claims. 1 to 3, additionally containing a stage, on which:
carry out the synchronization delay device (10) monitoring the patient in response to at least one of the things that 1) open the patient's record, 2) perform measurement of the patient, 3) print patient records, or 4) send patient data.

5. The machine-readable storage medium containing software that controls the processor to perform the method according to any one of claims. 1-4.

6. The device (10) for monitoring a patient, comprising:
a plurality of sensors (16) arranged with the possibility to�Irat physiological patient data;
the processor (18), programmed to perform the method according to any one of claims. 1-4.

7. The device (10) for monitoring a patient, comprising:
a plurality of sensors (16), configured to collect physiological data from the patient;
the controller (18), made with the possibility of transmission of packets (70) of patient data generated by the collected physiological data to the Central server (12) and receiving messages (72) with acknowledgement (ACK) from the Central server (12) in response to receipt of the package (70) of patient data, and the message (72) with confirmation contains a mark (74) time provided by a clock (46) Central server (12), indicating the time and date when the Central server (12) received packet (70) patient data;
watch (28); and
block (32) synchronization, configured to synchronize the clock (28) in accordance with date and time stamp (74) of the time in the message (72) ASC, if the difference between the mark (74) of the time in the message (72) with ASA and clock (28) of the device (10) monitoring of the patient is greater than the first predefined length of time.

8. Device monitoring a patient according to claim 7, further comprising:
the display (22), arranged to display a warning (88) on the synchronization in response to the time change device (10) monitoring the patient during synchronization bole� than the second predetermined time.

9. The device (10) for monitoring a patient according to any of claims. 7 or 8, wherein the controller (18) is arranged to transfer the package (70) of dummy data to the Central server (12) in response to the lack of clock synchronization (28) of the device (10) monitoring the patient during the third predetermined time from the time the last comparison hours (28) of the device (10) monitoring the patient with a mark (74) of the time in the message (72) with ASA.

10. The device (10) for monitoring a patient according to any one of claims. 7-8, in which the controller (18) is arranged to generate and transmit packets (70) of the data indicates that changing the clock time (28) exceeds a second predetermined amount in response to what the difference is marked (74) time of message (72) with ASA exceeds the first predefined length of time.

11. The patient monitoring system, comprising:
many devices (10) for monitoring a patient according to any one of claims. 7-10;
the Central server (12), configured to send the message (72) with acknowledgement (ACK) in response to receipt of the package (70) of patient data from the device (10) monitoring of the patient, and the message (72) ASC contains a mark (74) time provided by a clock (46) Central server (12), indicating the time and date when the Central server (12) adopted a package of 70) patient data.

12. The patient monitoring system according to claim 11, in which the Central server contains:
memory (20) of patient records;
the controller (18), made with possibility of reception of the package (70) of patient data, send messages (72) with ASA and storage of patient records patient data from packets (70) of patient data and messages relating to changes with time in hours (28) of the device for monitoring the patient during synchronization.

13. The patient monitoring system according to any one of claims. 11 or 12, further comprising:
the server (34) of the time, made with the possibility of periodic correction of the clock (46) Central server (12).



 

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20 cl, 9 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical working process of visualisation. System contains: control unit (114), containing processor (116); and multitude of processing executives (102), connected with it, with processor (116) realising control of realisation with feedback of plane of medical visualisation working process by means of multitude of processing executives (102), and processor (116) is made with possibility of inquiring electronic medical information, dealing with and/or not dealing with visualisation from one or more processing executives; formation of plan of visualisation procedure working process by means of visualisation procedure, based on information inquired; reception of signal, indicating due date of planned visualisation procedure; downloading visualisation protocol, corresponding to visualisation procedure, into visualisation system, used for visualisation procedure; realisation of scanning by means of visualisation system; and updating plan of visualisation procedure working process.

EFFECT: increased reliability of patient diagnostics.

15 cl, 9 dwg

FIELD: physics, computer engineering.

SUBSTANCE: invention relates to systems and methods of conducting a transaction to acquire available goods or services using stored means associated with designation. The methods include: receiving, at a point of sale, identifiers of goods or services selected for acquisition, and designation; determining if the goods or services comprise available goods or services; calculating the sum required to acquire the available goods or services; determining if the stored means are enough to acquire the available goods or services; using the stored means to acquire the available goods or services; and using an additional funding source provided by the customer to acquire any goods or services which are not available goods or services. The system implements said methods.

EFFECT: high accuracy and reliability of a transaction, which includes an additional alternative source.

18 cl, 9 dwg

FIELD: medicine.

SUBSTANCE: non-invasive examination of vessels is performed by means of a probe, installed on the skin surface in the projection of a vessel, by a method of optic coherent (OC) tomography, tomograms, obtained without compression test and OC tomograms under conditions of the compression test by the displacement of tissues by the probe by 1 mm towards the visualised vessel, are analysed. Compressibility of the vessel, tissues and formations and uniformity of the vessel configuration change under compression are estimated on the images. If a non-uniform and/or incomplete compressibility and a non-uniformity of the vessel configuration change are detected, microangiopathy is identified.

EFFECT: method ensures the high accuracy and objectivity of non-invasive diagnostics of the condition of microvasculature, in particular, the presence of intra-vascular formations, including differential diagnostics of vasculopathy due to the identification of particular criteria for the determination of pathological changes.

5 dwg, 4 ex

FIELD: chemistry.

SUBSTANCE: group of inventions relates to surface hydrophilisation and immobilisation of antibodies on the surface of a cycloolefin copolymer. Disclosed method of making a capillary-action analytical device, which includes steps of: a) providing a capillary substrate, b) changing the hydrophilic property of the surface, c) mixing a matrix and immobilised molecules in solution form to obtain a solution which includes immobilised molecules covalently bonded to the matrix, and d) depositing the solution on a well defined region in at least one storage area. Also a capillary-action analytical device made using said method is described.

EFFECT: enabling change of the substrate by chemical treatment of the surface and depositing immobilised molecules in an optimum matrix on given regions, with less consumption of matrix material, which enables to use several different matrix material in the same chip.

33 cl, 3 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medical working process of visualisation. System contains: control unit (114), containing processor (116); and multitude of processing executives (102), connected with it, with processor (116) realising control of realisation with feedback of plane of medical visualisation working process by means of multitude of processing executives (102), and processor (116) is made with possibility of inquiring electronic medical information, dealing with and/or not dealing with visualisation from one or more processing executives; formation of plan of visualisation procedure working process by means of visualisation procedure, based on information inquired; reception of signal, indicating due date of planned visualisation procedure; downloading visualisation protocol, corresponding to visualisation procedure, into visualisation system, used for visualisation procedure; realisation of scanning by means of visualisation system; and updating plan of visualisation procedure working process.

EFFECT: increased reliability of patient diagnostics.

15 cl, 9 dwg

FIELD: medicine.

SUBSTANCE: clinical research aimed at detection arterial hypertension is performed. Echocardiographic examination with the detection of signs of sclerogenic changes of the aorta is carried out. A value of function F is calculated. 2 demographic parameters - sex and age are taken into account, 1 clinical parameter is arterial hypertension and 1 echocardiographic parameter - presence of the sclerogenic injury of the aorta. Then the value of a probability level P is calculated. Patients with unchanged coronary arteries have the value P lower or equal 0.204. In patients with non-obstructive coronary-sclerosis it is over 0.204.

EFFECT: method makes it possible to exactly, at early stages of the disease, carry out non-invasive diagnostics, determine indications for effective treatment actions, ensures the prevention of complications due to the application of available clinical and instrumental methods, including in calculation most significant clinical signs, application of methods of determining the probability of the presence of non-obstructive coronary-sclerosis.

2 dwg, 2 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: blood pressure is measured according to the standard procedure on the brachial artery by means of the Riva Rocci Korotkoff sphygmomanometer. The vegetative status is assessed by the rest heart rate variability parameters. The endothelial vasomotor function is described as a percentage measure of a resistance index after inhalation of Salbutamol 400 mcg, an endothelium-dependent vasodilator as related to a basal resistance index by photoplethysmography. The derived data are used to determine an adequate basal pulse wave velocity and a pulse wave velocity following the sublingual administration of nitroglycerin 500 mcg, for each patient individually by original formulas.

EFFECT: method enables providing the more accurate determination of the adequate basal pulse wave velocities and the pulse wave velocity following the administration of nitroglycerin taking into account the vegetative status.

2 dwg, 1 tbl, 1 ex

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine, namely to organising and conducting insulin therapy for a patient. Determining a user's dose of basal insulin is ensured by using a device for insulin administration and a portable device for diabetic data control. The method involves measuring the number of the user's blood glucose concentrations over the number of time intervals. The collected data are used to state if the user has performed the minimum number of measurements of the fasting blood glucose concentration over at least one of the four time intervals prescribed. That is followed by stating if the collected data indicate one of the first schedule showing the low blood glucose concentration, and the second schedule showing the lower blood glucose concentration than in the first schedule showing the low glucose concentration. Thereafter, the method provides considering if the basal insulin dose correction in the portable device for the first and second schedules correspond to each other; the user is warned, and the basal insulin dose correction is prohibited in any of the devices. Taking preventive measures aiming at measuring the basal insulin dose by means of the devices involves collecting the data, and the preventive measures are taken to avoid the user's hypoglycaemic state.

EFFECT: group of inventions enables rendering aid in the patients suffering from diabetes by means of the devices for determining the basal insulin dose and controlling the blood dose level in an insulin dose and taking the preventive measures.

27 cl, 11 dwg

FIELD: medicine.

SUBSTANCE: neurovisualisation examination of brain is carried out, Cirs comorbidity index and Kaplan-Feinstein comorbidity index are determined, cochleovestibular syndrome, eye-moving impairments, type of diabetes mellitus are identified. Value of discriminate function (D) is calculated. If D value is higher than zero, diagnosed are consequences of ischemic brain stroke (IBS) with hyperhomocysteinemia (HH), if D is lower than zero, consequences of IBS without HH are diagnosed.

EFFECT: method makes it possible to increase reliability of diagnostics of IBS consequences, which is achieved due to complex analysis of said parameters.

2 ex

FIELD: medicine.

SUBSTANCE: invention relates to control of sugar level in blood. Method contains the following stages: multitude of measurements of glucose level in user's blood is carried out by means of microprocessor; multitude of measurements of glucose level in blood is stored in memory device; it is determined whether the last measurement of glucose level in blood, performed at specified moment of time during the day, is lower than the first threshold, which constitutes about 70 mg of glucose per decilitre of blood, or higher than the second threshold, which constitutes about 150 ml of glucose per decilitre of blood; it is estimated by means of microprocessor if, at least, one measurement of glucose level from multitude of measurements, carried out in time interval approximately 3-hour long relative to specified time, at which the last measurement of glucose level in blood for previous days, was lower the first threshold or higher than second threshold; it is notified that for the same time period for previous days multitude of measurements of glucose level in blood shows the tendency of reduction of glucose level in blood relative to the first threshold or of increase of glucose layer relative to the second threshold.

EFFECT: increased accuracy of determination of user's state for control of diabetes course.

24 cl, 17 dwg

FIELD: medicine.

SUBSTANCE: individual's back relief is visualised by stereophotographying followed by the stage of digital modelling and colour relief mapping. The stereoimage relieves of frontal and dorsal body parts are used to construct a set of cross sections of the front and back body parts at the different levels to form the full cross section of the body. Positions of sternum, spinal column and its spinous processes are marked by drawing a body boundary line on the right and left parts through them. That is followed by calculating areas of the right- and left-sided components of the full section of the body, coordinates of their geometrical centres to assess a displacement of each of the mentioned parameters and the spines in relation to a vertical drawn from an apex of gluteal fold That is followed by assessing variations of the body shape or its segments, whereas the derived parameters are used to assess the progression of a pathology or to assess the correction effect.

EFFECT: accurate detection and assessment of the individual's body shape asymmetry in any segment.

6 dwg

FIELD: medicine.

SUBSTANCE: invention relates to means for glucose level control. The method of presenting information about the analyte concentration consists in the following: a value of concentration of at least one analyte, present in each of a multitude of physiological samples, taken during the first preliminarily determined time interval, is measured by means of an analyte sensor, the values of the analyte concentration are stored, the accordance of the quantity of the stored values of the analyte concentration to the minimal threshold value is determined, current measurement of the analyte concentration is presented simultaneously with at least one of the two selected headlines of the message, containing an overview of the stored values of the analyte concentration for the preliminarily determined time interval or a model of tendency in the change of the stored values of the analyte concentration, and the message is demonstrated after the selection of a message headline for the model of change tendency for the second preliminarily determined time interval. The second version of the method includes an additional notification by the message after the selection of the heading for an overview of the stored values of the analyte concentration, showing the distribution of values for one of the preliminarily determined ranges, the first threshold or the second threshold, exceeding the first threshold values. The third version includes the estimation, after the determination of the correspondence of the quantity of measurements to the minimal threshold value, of the correspondence of the stored values of the analyte concentration to one or several rules, preliminarily stored in a measuring device, in order to form the message, which contains some of the stored values as a part of the message, sent to the user, with the presentation of the current analyte measurement and simultaneous demonstration of the message to the user as the first message, received by the user before receiving any other messages. In the fourth version of the method implementation, after the determination of the accordance of the quantity of measurements to the minimal threshold value, estimated is the correspondence of the stored values of the analyte concentration to one or several rules, preliminarily stored in the measuring device, in order to form the message, which contains some of the stored values as a part of the message, sent to the user, with the presentation of the current measurement of the analyte concentration from the measurement stage and simultaneous demonstration of the message to the user after the measurement stage. In the fifth version the tendency of change of glucose concentration values towards a decrease, identified on a particular day, in which at least one value of the glucose concentration is lower than the second preliminarily determined threshold on each of the three last days is additionally automatically identified for the particular day, the tendency of change of the glucose concentration values towards an increase, identified on a particular day, on which at least one value of the glucose concentration is higher than the first preliminarily determined threshold on one of the three last days within one and the same time interval, with sending to the user a multitude of dates, on each of which there is only one corresponding message, with such a corresponding message containing data about either the tendency of change of the values towards the increase or the tendency of change of the values towards the decrease, and if on one particular date both tendencies are identified, the user is informed only about the tendency of change of the values towards the decrease.

EFFECT: application of the invention makes it possible to simplify control and increase the accuracy of measuring the glucose level in blood.

18 cl, 8 dwg

FIELD: medicine.

SUBSTANCE: method involves carrying out ultrasonic scanning examination of subclavian artery over its whole extent in physiological arm position with arterial blood pressure being measured in the middle one third of the arm. Next, when applying compression tests, blood circulation parameters variations are recorded in distal segment of the subclavian artery with arterial blood pressure being concurrently measured. Three degrees of superior thorax aperture syndrome severity are diagnosed depending on reduction of linear blood circulation velocity and arterial blood pressure compared to their initial values. Mild one takes place when linear blood circulation velocity reduction reaches 40% and arterial blood pressure 20% of initial level, moderate one when linear blood circulation velocity reduction reaches 70% and arterial blood pressure 50% and heavy one when linear blood circulation velocity reduction is greater than 70% of initial level and arterial blood pressure is greater than 50% to the extent of no blood circulation manifestation being observed in the subclavian artery.

EFFECT: high accuracy of diagnosis.

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