System and method for controlling leak from contour, delivering to subject suitable for breathing gas flow under pressure

FIELD: medicine.

SUBSTANCE: group of inventions relates to medical equipment. The system contains a gas contour, consisting of an input branch pipe, an output branch pipe and a hollow channel, connecting the input branch pipe and the output branch pipe, with the output branch pipe being configured for the delivery of a flow of suitable for breathing gas under pressure into the subject's airways. A valve is configured for the output of the gas from the contour into atmosphere. One or more sensors are configured for the generation of one or more output signals, transmitting the information, related to one or more gas parameters within the gas contour, connected with gas leak from the contour into atmosphere. A processor is configured for controlling the valve in such a way that the gas flow, being output from the contour through the valve, is reduced or stopped, if one or more output signals, generated by one or more sensors indicate that the gas leak from the contour into atmosphere exceeds the threshold. A constructively differing version of the system implementation is disclosed.

EFFECT: inventions make it possible to control leaks from the gas contour to preserve its workability.

8 cl, 3 dwg

 

The invention relates to the delivery of the pressurized flow of breathable gas to the subject through the circuit under dynamic control of gas leakage from the circuit to the atmosphere.

The known systems are configured to deliver the pressurized flow of breathable gas to the airway of the subject with natural ventilation for therapeutic purposes. For example, a system of positive airway pressure are typically used to maintain pressure in the Airways of subjects during sleep in order to relieve the symptoms of respiratory disorders during sleep. These systems deliver the pressurized flow of breathable gas through the circuit, which often contains the mechanism of leakage of gas into the atmosphere in order to prevent rebreathing. However, these mechanisms usually have a fixed structure and provide a leak circuit is a static image.

One aspect of the invention relates to a system configured to deliver the pressurized flow of breathable gas to the airway of the subject. In one embodiment, the implementation of the system contains the gas circuit, valve, one or more sensors and a processor. The gas circuit consists of an inlet pipe, outlet pipe and the hollow channel�, which connects an inlet and an outlet. Exhaust outlet configured to deliver the pressurized flow of breathable gas to the airway of the subject. The valve is configured to discharge the gas from the circuit to the atmosphere. One or more sensors configured to generate one or more output signals that convey information related to one or more parameters of the gas within the circuit related to the leakage of gas from the circuit to the atmosphere. A processor configured to control the valve such that the volume of gas produced from the circuit to the atmosphere, based on one or more output signals generated by one or more sensors.

Another aspect of the invention relates to a method of delivery of the pressurized flow of breathable gas to the airway of the subject. In one embodiment of the method includes delivering the pressurized flow of breathable gas to the airway of the subject through the circuit, which is connected with the respiratory tract of a subject; generating one or more output signals that convey information related to one or more parameters of the gas in the pressurized flow of breathable gas leak-related �Aza in the pressurized flow of breathable gas from the circuit to the atmosphere; and the emission of gas from the circuit to the atmosphere with a controlled speed based on one or more output signals generated by one or more sensors.

Another aspect of the invention relates to a system configured to deliver the pressurized flow of breathable gas to the airway of the subject. In one embodiment of the system includes means for delivering the pressurized flow of breathable gas to the airway of a subject, wherein the means for delivering is connected to the airway of the subject; means for generating one or more output signals that convey information related to one or more parameters of the gas in the pressurized flow of breathable gas that is related to a gas leak in the pressurized flow of breathable gas from the residual gas into the atmosphere; and means for releasing gas from the means for delivery into the atmosphere with a controlled speed, based on one or more output signals generated by one or more sensors.

These and other objectives, features and characteristics of the present invention, as well as methods of operation and functions of the respective elements of the structure, and combination of parts, and the organization of production will be �more clear upon consideration of the following description and the attached claims, with reference to the accompanying drawings, all of these sections form part of this specification, and wherein similar digital positions denote corresponding parts in different figures. It should be clear that the drawings are only for purposes of illustration and description and are not limiting of the invention. In addition, it should be understood that the structural features shown or described herein, in a variant implementation, can also be used in other embodiments. However, it should be clearly understood that the drawings are only for purposes of illustration and description and are not intended to define the scope of the invention. When used in the specification and claims, the singular includes a reference to a set of objects, if the context is not clearly defined herein.

Fig.1 illustrates a system configured to deliver the pressurized flow of breathable gas to the airway of a subject, in accordance with one or more embodiments of the invention.

Fig.2 is a graph parameter related to leakage, depending on the pressure in the interface device, in accordance with one or more embodiments of the invention.

Fig.3 contains graphs of the argument from�of samegawa to the drain, pressure in the interface device and mode of functioning of the valve, in accordance with one or more embodiments of the invention.

Fig.1 illustrates a system 10 configured to deliver the pressurized flow of breathable gas to the airway of subject 12. In particular, the system 10 is configured to deliver the pressurized flow of breathable gas to the airway of subject 12 as part of a treatment regimen. In the process of delivery of the pressurized flow of breathable gas to the airway of subject 12, the system 10 adaptively and/or dynamically adjusts the amount of gas that leaks to the atmosphere in order to prevent recurrent respiratory gas of the subject 12 based on the volume of gas that leaked into the atmosphere "unintentionally". In one of the embodiments of the system 10 includes a pressure generator 14, the circuit 16, one or more sensors 18, one or more valves 20 and processor 22.

The pressure generator 14 is configured to generate a pressurized flow of breathable gas for delivery to the airway of subject 12 via a circuit 16. One or more parameters of the pressurized flow of breathable gas generated by pressure generator 14 may be controlled in�testii with parameters of a treatment regimen. therapy regimen may include, for example, the algorithm of therapy pressure, designed to maintain positive pressure in the airway of subject 12 with natural ventilation during sleep. Support the positive airway pressure provided to the subject 12, will provide therapeutic benefit to the subject 12, which reduce the symptoms of respiratory disorders during sleep experienced by subject 12. Algorithm therapy pressure may include one or more of the algorithm bi-PAP, CPAP algorithm, CPAP auto titration, servoventilation, auxiliary respiration, components of comfort, such as C-Flex, reducing the pressure during early exhalation and/or other algorithms of therapy pressure. One or more parameters of the pressurized flow of breathable gas are controlled in accordance with the mode of therapy may include one or more parameters of pressure, flow rate, composition, volume, temperature, humidity and/or other parameters of the pressurized flow of breathable gas. In one of the embodiments of the pressure generator 14 comprises a source of 24 gas and a device 26 to maintain the pressure.

Source 24 gas includes the storage or storage of gas, the device 26 to maintain the d�effect creates a pressurized flow of breathable gas, which is delivered to subject 12. Source 24 gas may include any gas supply for breathing, such as, for example, ambient atmosphere, a reservoir of compressed gas, wall gas source and/or other repositories of breathable gas. Gas for breathing from the source 24 gas can be a breathable gas, such as air, oxygen, an oxygen mixture, the gas mixture for breathing and medicines, which may be in gaseous form (e.g., in the form of oxide, in atomized form, etc.), and/or other breathable gases.

The device 26 to maintain the pressure includes one or more controls of one or more parameters of the flow of breathable gas released from the device 26 to maintain the pressure in the circuit 16 (for example, pressure, flow, etc.). For example, the device 26 to maintain the pressure may include one or more valves, compressors, pistons, bellows and/or other mechanisms for monitoring one or more parameters of the flow of breathable gas. The device 26 to maintain the pressure may comprise a device maintaining a positive pressure in the airway configured to generate the pressurized flow of breathable gas for delivery to the subject 12 in a suitable�and mode of therapy, designed to relieve the symptoms of respiratory disorders during sleep experienced by subject 12 during sleep.

Circuit 16 determines the flow path of gas between the pressure generator 14 and the airway of subject 12. Thus, the circuit 16 is configured to deliver the pressurized flow of gas from pressure generator 14 to the airway of subject 12. In one embodiment of the circuit 16 includes one or more interface devices 28 and duct 30.

The interface device 28 is configured to transfer gas between the airway of subject 12 and the circuit 16. The interface device 28 may include invasive or non-invasive device for the transmission of gas between the circuit 16 and the airway of subject 12. For example, the interface device 28 may include a nasal mask, nasal/oral mask, obdelavo mask, nasal cannula, endotracheal tube, LMA, tracheal tube and/or other interface device.

The duct 30 forms a hollow channel between the inlet circuit 16, which is connected to the device 26 to maintain the pressure in the outlet circuit 16 formed by an interface device 28. In one of the embodiments of the air duct 30 is flexible. The duct 30 may be implemented as a single unit with �interfacenum device 28. Or the duct 30 may be implemented separately from the interface device 28. In one of the embodiments in which the duct 30 and an interface unit 28 are implemented separately, the duct 30 and an interface unit 28 are selectively removable.

Despite the fact that the circuit 16 is illustrated in Fig.1 as consisting of a single channel circuit for transmitting the pressurized flow of breathable gas to the airway of subject 12, it is assumed that this is a limitation. In one embodiment of the circuit 16 is a circuit consisting of two channels, with a separate part (e.g., a separate channel of the duct 30) configured for transmission of gas from the airway of subject 12.

Typically, the interface between the interface device 28 and airway of the patient 12 is not ideal. For example, if the interface device 28 includes a mask that covers the nose and/or mouth of the subject 12, a hermetic seal between the mask and the face of subject 12 may not be perfect, and may allow a certain volume of gas from the mask to leak into the atmosphere. These types of leakage between the interface of the interface device 28 and the airway of subject 12 is also commonly found in other types of interface devices. Similarly, one in�options the implementation of the circuit 16 also contains other sources of leakage from the circuit 16 to the atmosphere. For example, gas may leak into the atmosphere from the connection between the interface device 28 and duct 30 and/or from the connection between the duct 30 and the device 26 to maintain the pressure. In addition, the interface device 28 and/or the duct 30 may have leaks that allow gas from the circuit 16 to leak into the surrounding atmosphere. Such leaks can be specially created within the interface device 28 and/or the duct 30 and/or may be formed in an interface device 28 and/or the duct 30 as a result of use (for example, due to normal wear).

A gas leak from the circuit 16 to the atmosphere during the delivery of the pressurized flow of breathable gas to a subject 12 may be benefits to the system 10. During use in the delivery process circuit 16 of the pressurized flow of breathable gas to the airway of subject 12, the exhalation of the subject 12 are sent back to the circuit 16. The introduction of the exhaled gas within circuit 16 increases the pressure in the circuit 16 and the increase in the content of carbon dioxide in the circuit 16. If some amount of exhaled gas is introduced into the circuit 16 during inhalation and exhalation does not arise from the circuit 16 to the atmosphere, the subject 12 may not receive enough oxygen from the pressurized stream suitable d�I breathing gas due to rebreathing.

Despite the fact that the diversion of at least part of the gas from the circuit 16 to the atmosphere, in some way favourable to the system 10 (in particular, a gas leak near the interface between the subject 12 and the circuit 16, to which the greater the likelihood that it will be a high content of carbon dioxide, excessive leakage may reduce the comfort, efficiency, performance and/or ease of treatment provided to subject 12 by system 10. For example, excessive leakage from the circuit 16 to the atmosphere can increase the volume of the audible noise generated by the system 10, to degrade the pressure regulation circuit 16, to degrade the detection of respiratory events based on the parameters of gas in the circuit 16 (e.g., a processor associated with the pressure generator 14), to increase the load of the generator 14 to the pressure required to maintain the necessary pressure in the circuit 16, and/or some other way to reduce the comfort, efficiency, performance and/or ease of treatment provided to subject 12 by system 10.

The sensors 18 are configured to monitor one or more parameters of the pressurized flow of breathable gas delivered to the airway of subject 12. For example, sensors 18 may include one or more sensors configured to generate output signals from�sasisa to one or more parameters of pressure, the flow rate, composition, volume, temperature, humidity and/or other parameters of the pressurized flow of breathable gas. Such sensors may include, for example, one or more sensors of the pressure sensor, flowmeter, capnometer and/or other sensors configured to generate output signals conveying information related to one or more parameters of the pressurized flow of breathable gas. The sensors 18 may be placed in the system 10 so as to communicate with the pressurized flow of breathable gas within the device 26 to maintain the pressure inside interface devices 28, and/or within a hollow channel formed by the duct 30. For example, one or more sensors 18 may be placed in the system maintain a positive pressure in the Airways, which includes the device 26 to maintain the pressure, the interface device 28 and/or the duct 30.

One or more valves 20 is configured to discharge the gas from the circuit 16 to the atmosphere. One or more valves 20 is configured in such a way that the speed with which the gas is discharged from the circuit 16 to the atmosphere is controlled. Control of the rate at which one or more valves 20 release the gas from the circuit 16 in atmospheres�, allows you to control the amount of leakage from the circuit 16 to the atmosphere (e.g., in accordance with described in more detail below).

In one embodiment, the implementation of one or more valves 20 include binary valve with two States, which can operate in two modes. In the first mode, the valve releases the gas from the circuit 16 to the first speed. In the second mode, the valve releases the gas from the circuit 16 with the second speed. The first mode may represent an "open" mode, in which gas can pass quite freely through the opening formed by the valve. The second mode may be a "closed" mode in which the opening formed by the valve is mostly closed, whereby the second speed is zero or close to zero.

In one embodiment, the implementation of one or more valves 20 include a valve that can be controlled to allow for the passage of gas through the valve from the line 16 to the atmosphere with a variety of different speeds. To achieve this, the valve can provide a hole, the size of which can be adjusted incrementally, a lot of holes that can be selectively opened or closed individually or in groups, in order to adjust the speed at which the gas is released into the atmosphere, and/or may be used for other fur�the mechanisms of regulation of speed, with which the gas is released into the atmosphere.

In a variant implementation, shown in Fig.1, one or more valves 20 include a valve located on the interface device 28. This may contribute to the leakage of exhaled gas (such as having elevated levels of carbon dioxide) to prevent rebreathing. It should be understood that such arrangement is not intended as a limitation. In one embodiment, the implementation of one or more valves 20 include a valve located on the air duct 30. In one embodiment, the implementation of one or more valves 20 include valves located on the interface device 28 and the duct 30.

The processor 22 is configured to enable the processing of information in the system 10. Thus, the processor 22 may include one or more of a digital processor, an analog processor, a digital circuit designed to process information, an analog circuit designed to process information and/or control component (s) within the system 10, the state machine, and/or other mechanisms for electronically processing information. Despite the fact that the processor 22 shown in Fig.1 as a single entity, this is done solely for illustrative purposes. In some implementations, the processor 22 may contain mn�a number of processing blocks of data. Such blocks of data can physically reside within the same device, or processor 22 may provide the functionality of a group of devices working together. The processor 22 may be configured to provide the functionality described below by performing one or more modules of computer programs. The processor 22 may be configured to execute modules by software; hardware; firmware; some combination of software, hardware and/or firmware; and/or other mechanisms for configuring processing capabilities of the data processor 22. The processor 22 may include one or more components placed integrally and/or the pressure generator 14, the interface device 28 and/or the duct 30.

As discussed above, during delivery of the pressurized flow of breathable gas to subject 12 by system 10, the gas from the circuit 16 will leak into the surrounding atmosphere. This process may include a gas leak is happening deliberately (e.g. to prevent recurrent respiratory) and/or the gas that leaked unintentionally (e.g., due to wear, leakage from the interface d�Kotelnich ways, etc.). The processor 22 is configured to control one or more valves 20 to control leakage from the circuit 16 to the atmosphere with the aim of improving the efficiency, comfort and/or convenience of therapy provided to subject 12 by system 10 by the pressurized flow of breathable gas. In particular, the processor 22 is configured to stabilize the leakage from the circuit 16 to the atmosphere.

In order to stabilize the leakage from the circuit 16 to the atmosphere by controlling one or more valves 20, the processor 22 manages the one or more valves 20 based on one or more output signals generated by sensors 18. More specifically, the control valves 20 by processor 22 based on the output signals generated by the sensors 18, which is passed to the parameter information of gas in the circuit 16, relating to a gas leak from the circuit 16 to the atmosphere. As a non-limiting example, the parameter of gas from the circuit 16, which is the control valve 20 may include a gas flow rate in the circuit 16 or measurement of the flow rate of produced gas into the atmosphere from the circuit 16.

In one of the embodiments, the processor 22 controls the valve 20 with the aim of gradually reducing the speed with which the gas flows away from the circuit 16 to the atmosphere, in the case where output signals, with�everyoane sensors 18, indicate that the leakage increases. For example, the area of the hole (s) valve 20, through which gas may flow from the line 16 to the atmosphere can be determined as a function of (e.g. proportional to) the gas parameter related to leakage from the circuit 16. Dynamic configuration of this type will lead to a decrease in the volume of gas flowing to atmosphere through the valve 20, since the amount of unintended leaks of gas from the circuit 16 to the atmosphere increases, and Vice versa.

In some embodiments, the valves 20 include binary valve with two States, which can operate in the first mode and the second mode. If the valve 20 operates in the first mode, the valve 20 provides for the formation of the openings of the first size, through which the flowing gas from the circuit 16. If the valve 20 operates in the second mode, the valve 20 provides for the formation of holes smaller than the first hole, or even ensures no holes. If the valve 20 is configured so that the aperture in the second mode, closed or mostly closed, the valve 20 is essentially disabled in the second mode.

In these embodiments, processor 22 may control the valve 20 so that the valve 20 is switched by the processor 22 between the first mode and the second mode on the basis of point l� output signals, generated by sensors 18, the amount of leakage that exceeds one or more threshold values. For example, in one embodiment of the output signals generated by sensors 18, transmit information about the first parameter of gas related to gas leakage from the circuit 16 to the atmosphere. The first parameter of the gas may include, for example, the flow rate in the circuit 16 and/or measurement of the flow rate of the leak. If the output signals generated by sensors 18, indicate that the first parameter of gas exceeded the upper threshold level (e.g., output signals exceeded the relevant threshold level), the controller 22 controls the valve 20 for the purpose of switching from the first mode to the second mode, thereby decreasing the volume of leakage.

After the valve 20 is switched to the second mode of operation, the processor 22 over time can execute a control valve 20 for the purpose of switching back to the first mode of operation. For example, the processor 22 can switch the valve 20 back to the first mode of operation after a predetermined period of time. As another example, the processor 22 can maintain the valve 20 in the second mode of operation as long as the value of the first parameter of the gas drops below the threshold level. If the output signals generated by the sensor�mi 18, indicate that the value of the first parameter of gas fell below the lower threshold level (e.g., output signals fell below the relevant threshold level), the CPU 22 controls the valve 20, for the purpose of switching from the second operation mode back to the first mode of operation, thereby increasing the rate at which gas flows through the valve 20 to the atmosphere.

In one embodiment, the implementation of the threshold (th) level(-Ni) for the first parameter of the gas, which are used to control the valve 20 includes at least one threshold level, which is static and fixed. The user may configure the at least one level, or the at least one threshold may be set during manufacture. In one embodiment, the implementation of the threshold (th) level(-Ni) for the first parameter of gas that(-e) used is (are) to control the valve 20, comprise (s) at least one threshold that is adaptive and dynamic. This at least one threshold level may be determined based on the output signals generated by sensors 18. For example, the output signals generated by sensors 18 may transmit information about the second parameter of the gas in the circuit 16, and the at least Odie� threshold level may be determined based on the second parameter of the gas. The second parameter of the gas may include, for example, the pressure circuit 16, the pressure in the interface device 28, the pressure in the circuit 30, and/or other gas parameters.

As an illustration in Fig.2 shows a graph of the parameter related to leakage (e.g., the first gas parameter, described above) depending on the pressure in the interface device (e.g., interface device 28 shown in Fig.1 and described above). The graph in Fig.2 includes upper threshold level 32 for the parameter related to leakage, and lower threshold level 34 for the parameter related to leakage. In a variant implementation, illustrated in Fig.2, as the upper threshold level 32 and the lower threshold level 34 vary as a function of pressure in the interface device.

The schedule includes three pivot points 36, 38 and 40 which illustrates a method whereby a valve, which is the same as the valve 20 (shown in Fig.1 and described above) or equivalent, is controlled in accordance with the high threshold level 32 and the lower threshold level 34. The pivot 36 is located between the upper threshold level 32 and the lower threshold level 34. If the parameter related to leakage, corresponds to the pivot point 36, the valve will continue to operate in its current mode. For example, if p�d the pressure of the flow of breathable gas was recently launched and the valve is in the first mode by default (for example, the mode "open", described above), the valve will remain in this mode the pivot point 36.

The pivot 38 is located above the threshold level 32. Thus, if the parameter related to leakage, is moving from the reference point 36 to the pivot point 38, the valve is switched from the first operation mode to the second mode of operation, which reduces or even mostly stops leakage of gas through the valve (e.g., the second mode described above). This will reduce the value of the parameter related to leakage. For example, the switching valve from the first mode to the second mode can lead to the fact that the parameter related to leakage, will be back in the anchor point 36 or its neighborhood. After returning to the reference point 36 or the neighborhood valve will remain in the second mode of operation.

The pivot 40 is located below the threshold level 34. Thus, if the parameter related to leakage, moves from the reference point 36 or its surroundings (after the valve has been switched to the second operation mode) to the pivot point 40, the valve switches back to the first mode of operation. This will increase the value of the parameter related to leakage. For example, the switching valve back to the first mode may lead to the fact that the parameter related to leakage, will return�I'm back to the pivot point 36 or its neighborhood.

Fig.3 illustrates the method by which the dynamic thresholds are used to control the valve, which is the same as the valve 20 (shown in Fig.1 and described above) or an equivalent. In one embodiment, the implementation of management, illustrated by graphs shown in Fig.3, is realized through the control valve by means of a processor such as the processor 22 (shown in Fig.1 and described above). Fig.3 contains three graphs 42, 44 and 46. Graph 42 is a graph parameter related to leakage, depending on time. Graph 44 is a graph of pressure in the interface device, depending on time. Graph 46 is a graph of the mode of functioning of the valve (e.g., the first open mode or a second, closed mode).

On the chart 42 on the same time axis shows the upper threshold level 48 and the lower threshold level 50 for the parameter related to leakage. As can be seen in Fig.3, the upper threshold level 48 and the lower threshold level 50 is dependent on the pressure in the interface device. In particular, Fig.3 shows that in the case when the pressure in the interface device (see figure 44) falls within the time periods D and G, respectively, the upper threshold level 48 and the lower threshold level 50 experience correspond�her fall.

Fig.3 also illustrates how the mode in which operates a valve in a given time, is determined by the parameter related to leakage, and threshold levels 48 and 50. In particular, at the time A valve is in the first mode of operation, and the level of the parameter related to leakage, is between the upper threshold level 48 and the lower threshold level 50. At time points B and F, the level of the parameter related to leakage exceeds the upper threshold level 48. In response, the mode valve is switched from the first operation mode to the second mode of operation, whereby reduced leakage and decreases the level of the parameter related to leakage, returning to a value between the threshold levels 48 and 50. At the time points E and G the level of the parameter related to leakage falls below the lower threshold level 50. This leads to the fact that the valve switches back from the second mode of operation in the first mode of operation, whereby increased leakage and increases the level of the parameter related to leakage, resulting in the parameter again is between the threshold levels 48 and 50.

Although the invention has been described in detail for purposes of illustration based on what is currently considered the most practical and pre�respectful variants of implementation, it should be understood that these details are included solely for the purpose indicated, and that the invention is not limited to the described variants of implementation, but, on the contrary, it is assumed that it covers modifications and equivalent configurations that are within the form and scope of the attached claims. For example, it should be understood that the present invention assumes that, to the extent possible, one or more features of any embodiment can be combined with one or more features of any other embodiment.

1. The system for delivering the pressurized flow of breathable gas to the airway of a subject, comprising:
the gas circuit, consisting of an inlet pipe, outlet pipe and a hollow channel connecting an inlet and an outlet, the outlet configured to deliver the pressurized flow of breathable gas to the airway of the subject;
the valve is configured to discharge the gas from the circuit to the atmosphere;
one or more sensors configured to generate one or more output signals conveying information related to one or more parameters of the gas within the circuit relating to a gas leak from the circuit� into the atmosphere; and
a processor configured to control the valve so that the gas stream discharged from the circuit through the valve is reduced or stopped, if one or more output signals generated by one or more sensors indicate that the leakage of gas from the circuit to the atmosphere has exceeded the threshold.

2. A system according to claim 1, in which the threshold is dynamic and varies as a function of one or more gas parameters in the circuit.

3. A system according to claim 1, in which the circuit contains:
the front-end device of the subject that forms the discharge port of the circuit; and
the duct forming at least part of a hollow channel between the inlet and the outlet, wherein the air duct is connected to an interface device of the subject,
the valve is located on the interface device of the subject.

4. A system according to claim 1, in which one or more output signals to one or more sensors configured to transmit information related to pressure and/or flow rate in the circuit, or to both.

5. The system for delivering the pressurized flow of breathable gas to the airway of a subject, comprising:
means for delivering the pressurized flow of breathable gas to the airway of a subject, wherein the means for delivering connected � airway of the subject;
means generating one or more output signals conveying information related to one or more gas parameters of the pressurized flow of breathable gas that is related to a gas leak in the pressurized flow of breathable gas from the delivery means into the atmosphere; and
means for releasing gas from the delivery means into the atmosphere with a controlled speed based on one or more
the output signals generated by the generating means, and a means of letting off gas includes a means to reduce the speed at which the gas is released from the delivery means, in the case where one or more output signals generated by the generating means, indicate that the leakage of gas from the delivery means into the atmosphere has exceeded the threshold.

6. A system according to claim 5, in which the threshold is dynamic and which further comprises:
a means of determining the threshold as a function of one or more parameters of the gas in the delivery vehicle.

7. A system according to claim 5, in which the delivery vehicle includes:
the front-end device that is the subject, which is connected with the respiratory tract of the subject; and
the ductwork that delivers the flow of the pressurized flow of breathable gas to an interface device of the subject,
besides, the means of letting off incl�t in the valve, located on the interface device of the subject.

8. A system according to claim 5, in which one or more output signals convey information related to pressure and/or flow rate in the delivery vehicle, or to both.



 

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15 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: invention relates to sports medicine. Method includes carrying out interval hypoxic training with breathing gas mixture with simultaneous influence on central nervous system by pulse electric current. Before interval hypoxic training additionally realised is introduction of neuropeptide Semax in dose of two drops in each nasal passage. Interval hypoxic training is carried out at least four times by breathing gas mixture, which contains 9.5% of oxygen. Influence by electric current is realised with pulse duration 0.25-0.28 ms, current power 0.9 mA and frequency of pulses 1250 Hz for 60 minutes.

EFFECT: method ensures acceleration of organism readjustment to functioning in extreme conditions of influence, ensures increase of work efficiency.

1 tbl

FIELD: medicine.

SUBSTANCE: system comprises a breathing device, which is configured to generate a pressurized breathing gas flow into the airway, and respiratory indicators, which cause an individual breath so that the respiratory volume exceeds or is equal to the target respiratory volume. The respiratory indicators comprise the pressurized flow pressure fluctuation. Sensors form one or more output signals transmitting the information related to exhaled gas parameters, which are related to the respiratory volume. A processor is configured to provides modules. The parameter module is configured to determine a respiratory parameter of one or more output signals formed by one or more sensors. The respiratory parameter is either the respiratory volume, or the inhaled gas parameter related to the respiratory volume. The module of congruence is configured to compare the respiratory volume to a threshold, which corresponds to the target respiratory volume. The control module is configured to control the respiratory device to control the respiratory indicators presented for the individual by comparing the respiratory parameters and the threshold by the module of congruence. What is disclosed is a method for respiratory volume control.

EFFECT: providing the relation of the actual and target respiratory volumes.

6 cl, 4 dwg

FIELD: medicine.

SUBSTANCE: group of inventions relates to medical equipment. System for supporting positive pressure in patient's respiratory ways, when patient is breathing, contains respiratory device, made with possibility of controlling gas mixture flow between surrounding atmosphere and, at least, one external orifice of patient's respiratory ways. Respiratory device has first resistance to flow of gas mixture, flowing from surrounding atmosphere into patient's respiratory ways through respiratory device, and second resistance to flow of gas mixture, flowing from patient's respiratory ways into surrounding atmosphere through respiratory device. First resistance is less than second resistance, so that during inhalation gas mixture flows from surrounding atmosphere into patient's respiratory ways through respiratory device without delay. During exhalation second resistance of respiratory device to gas mixture, flowing from patient's respiratory ways into surrounding atmosphere, increases pressure inside patient's respiratory ways. Increased pressure supports patient's respiratory ways. Pressure generator is made with possibility to form flow of compressed respiratory mixture and providing additional support of patient's respiratory ways and is connected with case of respiratory device through contour, which gas mixture channel forms between respiratory device and pressure generator, by which flow of compressed respiratory mixture is supplied from pressure generator into patient's respiratory ways through respiratory device. First resistance constitutes less than approximately 0.025 cm of H2O with flow consumption 30 l/min. Second version of system, which is different in constructive implementation, is disclosed.

EFFECT: providing treatment of sleeping disorders due to creation of resistance to exhalation.

6 cl, 10 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used in treating the patients with respiratory impairments. A breathing support device comprises a first flow generator an output of which is connected to a patient's breathing system, and a control unit a first input of which is connected to the breathing system, and first and second outputs - to the first flow generator and the breathing system, respectively. The invention provides establishing a second flow generator, a probe inserted into the patient's gastrointestinal tract, a flow sensor and a pressure sensor. The second flow generator connected to the probe inserted into the patient's gastrointestinal tract at an input of which the flow sensor and the pressure sensor are mounted, respectively connected to third and fourth outputs of the control unit a fourth output of which is connected to a pulse oximeter, is connected to the third output of the control unit. The control unit is configured to start a procedure of extrapulmonary administration of oxygen, to determine pressure inside the gastrointestinal tract and controlled reduction of a volumetric flow rate.

EFFECT: enhancing by providing the additional extrapulmonary administration of oxygen into patient's body through the gastrointestinal tract.

1 dwg

FIELD: medical equipment, applicable for curative prophylaxis and for drug therapy of patients with bronchopulmonary diseases.

SUBSTANCE: the respiratory simulator consists of a mouthpiece - air conduit, casing with a cover, ball and a seat with a central hole making up a check valve. The check valve is made for closing at an expiration, its seat is made inside the casing in the form of a tapered recess in it and a central hole, by-pass channels are additionally made in the casing, a perforated diaphragm for limiting the ball motion is installed under the ball. The by-pass channels are made for adjustment of their area at an expiration or at an inhale, or simultaneously at an expiration and inhale and have a means for adjustment of the area of the by-pass channels. The means for adjustment of the area of the by-pass channels is made in the form of combined radial holes in the casing and ring and/or in the cover, and the cover and/or ring are made for restricted turning relative to the casing. The perforated diaphragm is made for tightening of the ball to the seat.

EFFECT: enhanced efficiency of treatment and simplified construction of the simulator.

14 cl, 16 dwg

FIELD: medicine, respiratory gymnastics.

SUBSTANCE: the present innovation deals with decreasing pulmonary ventilation in patient's endurable volume, controlling the rate for carbon dioxide (CO2) gain in expired air and maintaining the rate of its increase. Moreover, decreased pulmonary ventilation should be performed both at the state of rest and while doing physical loading, one should maintain the rate of CO2 gain in expired air being not above 2 mm mercury column/d at the state of rest and 11 mm mercury column in case physical loading to achieve the level of 32.1 mm mercury column at removing vivid symptoms of the disease and 55 mm mercury column in case of prolonged clinical remission. The method enables to improve therapy of hypocarbic diseases and states due to removing CO2 deficiency.

EFFECT: higher efficiency of therapy.

4 ex, 3 tbl

Air duct device // 2245725

FIELD: medical engineering.

SUBSTANCE: device has curved flexible air-conducting tube and mask segment. The mask segment is shaped to completely fit to the area above the laryngeal orifice. Supporting member has a set of thin flexible ribs branching out from core member stretching from opening area. Having the air duct device mounted, the flexible ribs thrust against the pharyngeal side of cricoid laryngeal cartilage immediately under the esophagus. The mask segment is fixed and thrusts against hard surface without injuring soft esophageal tissues. Versions of present invention differ in means for fixing around the laryngeal orifice of a patient.

EFFECT: enhanced effectiveness of lung ventilation in unconscious state.

14 cl,8 dwg

FIELD: medical engineering.

SUBSTANCE: device has chamber for accumulating carbon dioxide, bite-board and respiratory pipe. The chamber is manufactured as cylinder having conic bases arranged one in the other smoothly movable one relative to each other. The respiratory pipe with bite-board is available on one of external cylinder tips and single-acting valve with choker is available on the other tip allowing rotation for making resistance to expiration. Reservoir for collecting condensate is mounted on cylindrical surface the external cylinder. Pipe for taking air samples is available on distal external cylinder part cone base.

EFFECT: smoothly controlling expiration resistance and carbon dioxide concentration; enhanced effectiveness in separating air flows.

2 dwg, 1 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves applying diaphragmatic respiration with resistance to expiration. Overpressure equal to the resistance is created at inspiration stage. Breathing is carried out in usual pace in alternating A-type cycles as atmospheric air inspiration-expiration and B-type cycles as exhaled gas inspiration-expiration. Time proportion of breathing with exhaled gas to atmospheric air respiration is initially set not greater than 1. The value is gradually increased and respiration depth is reduced as organism adaptation to inhaled oxygen takes place, by increasing the number of B-type cycles and reducing the number of A-type cycles. Device has reservoir attached to mouth with individually selected expiration resistance. The reservoir has features for supporting gas overpressure at inspiration stage equal to one at expiration stage.

EFFECT: enhanced effectiveness of treatment; reduced volition effort required for training; improved operational functionality characteristics.

4 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: method involves introducing catheter via nasal passage into the rhinopharynx and fixed above the entrance to larynx and artificial high frequency jet ventilation is carried out with frequency of 140-150 cycles per min in three stages. Compressed gas working pressure is increased at the first stage to 2.0-2.5 kg of force/cm2 during 7-10 min. The compressed gas working pressure is supported at this level to the moment the clinic manifestations of pulmonary edema being removed and gas exchange normalization being achieved at the second stage. The working pressure is stepwise dropped during 1-2 h at the third stage hold during 10-15 min at each step.

EFFECT: enhanced effectiveness in normalizing hemodynamics.

FIELD: medical equipment.

SUBSTANCE: apparatus for artificial ventilation of lungs and inhalation narcosis can be used for emergency service and has unit for artificial ventilation of lungs, anesthetic unit and unit for alarm switch of anesthetic. Unit for artificial ventilation of lungs has oxygen discharge changing unit, flow meter, pneumatic pulse oscillator, nonreversible pneumatic valve which has access to patient's mask. Anesthetic unit has gas relation changing unit and mixer which has access to patient's mask. Unit for alarm switching anesthetic off is made is made in form of comparison unit which has pneumatic valve mounted in anesthetic feed line, two pneumatic relays and two regulators. Apparatus provides improvement in sensitivity to reduction in oxygen pressure in gas mixture.

EFFECT: widened operational capabilities; simplified exploitation; improved safety.

2 dwg

FIELD: medicine, anesthesiology, resuscitation.

SUBSTANCE: under conditions of artificial pulmonary ventilation at positive pressure at the end of expiration one should set the level of positive pressure at the end of expiration being above against pre-chosen optimal one for 4-8 cm water column. About 10-15 min later one should introduce perfluorocarbon as aerosol with the help of nebulizer for 10-15 min. The innovation enables to introduce perfluorocarbons without depressurization of respiratory contour, decreases damaging impact upon pulmonary parenchyma and, also, reduce invasiveness of the method and decrease expenses of perfluorocarbons.

EFFECT: higher efficiency of therapy.

1 ex

FIELD: medicine.

SUBSTANCE: method involves administering one of antyhypoxidant-antioxidant medicaments on empty stomach in age-specific dose before exposing a patient to cyclic treatment with gas medium. Hypoxi-hypercapnic gas mixture is applied as respiratory gas medium. Then, the patient is moved up for breathing with air-oxygen mixture. TcPO2 and/or SO2 restoration period being over, repeated hypoxi-hypercapnic treatment cycle is applied. The mentioned patient treatment cycles are applied in succession 4-10 times.

EFFECT: enhanced effectiveness of treatment; increased adaptation and reduced risk of side effects.

3 cl, 1 tbl

FIELD: medicine, in particular, exercising of respiratory organs in moderate hypoxia and hypercapnia mode with adjustable resistance to inhalation and expiration.

SUBSTANCE: respiratory exerciser has cylindrical mixing chamber with narrowed upper part, respiratory pipe connected to cylindrical mixing chamber, and bottom with perforations provided in its peripheral portion. Bottom of cylindrical chamber is made doubled. Members of porous material having predetermined density are located within bottom cavity. Central part of bottom is equipped with channel provided within cylindrical chamber and communicating with atmosphere. Inhalation indicator provided within channel is made in the form of movable piston member. Respiratory pipe is equipped with acoustic expiration indicator made in the form of unidirectional resonance whistle. Bottom inner cavity may be provided with additional replaceable loading inserts formed as film disks with openings having predetermined area and flexible loop attached to upper part of cylindrical chamber and having adjustable length.

EFFECT: reduced restrictions in orientation and fixing of exerciser position during usage and provision for indicating quality of expiration cycle.

3 cl, 2 dwg

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