Automated oxygen delivery system

FIELD: medicine.

SUBSTANCE: group of inventions refers to medical equipment. An automated oxygen delivery system comprises an patient's blood flow oxygen measuring sensor comprising a pulse oxymeter; a pneumatic sub-system comprising a gas feed connected to an oxygen inlet, an air inlet and a gas-mixture outlet for mixing oxygen and air to form gas mixture having the oxygen concentration delivered to the patient, and for delivering gas mixture to the patient; and a control sub-system connected to the sensor and the pneumatic sub-system comprising an input. A sensor interface is configured to receive the measurement data and the state information related to the sensor measurement data. The state information involves a perfusion index and a signal quality measure. A pneumatic sub-system interface is used to send commands and to receive the pneumatic sub-system data. A processor is connected to the input, the sensor interface and the pneumatic sub-system interface to control the supplied oxygen concentration on the basis of the required oxygen concentration, the measurement data and the state information. There are disclosed alternative versions of the automated system characterised by state information collecting media.

EFFECT: inventions provide the safe control of the supplied oxygen amount automatically.

27 cl, 5 dwg

 

The technical field to which the image belongs

The present invention generally relates to systems and methods of oxygen delivery. More specifically, the invention is directed to an automated system of oxygen delivery.

The level of technology

Many patients required respiratory support, including supplemental oxygen and/or assisted ventilation. Infants, particularly those born before term, may be unable to maintain adequate respiration and need support in the form of respiratory gaseous mixture, combined with the auxiliary ventilation. The breathing mixture is increased compared with room air fraction of oxygen (FiO2), while the auxiliary ventilation provides increased pressure in the upper respiratory tract. In a significant number of infants who receive respiratory support, episodes marked reduction of blood oxygen saturation or desaturation, i.e. the periods during which the utilization of oxygen in the lungs is disturbed and the saturation of oxygen in the blood falls. These seizures can occur up to twenty times per hour and each episode should be monitored by the treating physician.

Most of the systems existing prior art require the presence dejour�wow, controlling the oxygen saturation of blood and manually regulate the settings of a breathing apparatus for providing supplemental oxygen immediately after the detection of desaturation. Similarly, the duty to reduce supply the patient with oxygen, as the oxygen saturation of blood is restored to normal limits. The lack of the ability to quickly supply the patient with additional oxygen can lead to hypoxic-ischemic injury, including neurological damage, and in prolonged cases may cause death. Similarly, the inability to reduce the supply of oxygen to the patient after recovery also has clinical implications, the most frequent of which is retinopathy of prematurity, a form of blindness caused by oxidation visual sensory neurons. Despite the fact that at the current level of technology was made at least one attempt to create a closed system of automatic control supply FiO2using measurements of the patient's levels of oxygen saturation of hemoglobin in arterial blood, this system is not capable of safely and adequately define and align these erroneous measurements, putting the patient at greater risk for the development of at least the above-mentioned conditions.

Accordingly, it is necessary�widely regarded as one of the advanced system of oxygen delivery, which would in automatic mode safely control the quantity of oxygen to the patient based on the measured quantity in the blood flow of oxygen and associated with such measurement status.

Summary of the invention

Embodiments of the present invention preferably provide a system to automatically supply the patient with oxygen.

In one embodiment of the automated system of oxygen delivery includes a sensor measuring the amount of oxygen in the bloodstream of a patient, the Pneumatics subsystem and the control subsystem. The Pneumatics subsystem includes the intake of oxygen, air intake, release of gaseous mixture and a gas supply mechanism for mixing oxygen and air with the formation of a gaseous mixture having delivered oxygen concentration, and for delivering the gaseous mixture to the patient. The management subsystem includes an input device for obtaining the desired concentration of oxygen in the bloodstream of the patient, the touch interface for receiving measurement data and status information associated with received from the sensor measurement data, the interface subsystem Pneumatics to send commands and receive data from the Pneumatics subsystem and a processor for controlling the delivered oxygen concentration on the basis of desirable concentricycloidea, measurement data and status information. Thus, the broad description of some embodiments of the invention to present here a detailed description can be better understood, and in order to better perceived a real contribution to the technology. Of course, there are additional embodiment of the invention, which will be described below and disclosed in the accompanying claims.

In this regard, before a detailed explanation of at least one embodiment of the invention it should be understood that the present invention is not limited to the details of construction and the unit blocks set forth in the following description or shown in the drawings. In addition to described, the present invention is suitable for implementation in the form of other embodiments and can be applied and implemented in various ways. In addition, it should be understood that the phraseology and terminology, as well as the abstract shall serve only for purposes of description and should not be construed as restrictive.

In this regard, the experts in this field it is obvious that the conception on which this disclosure is based, can easily be used as a basis for designing other structures, methods and systems that enable the realization of certain objectives of the present invention. So is�tsya important, that the claims be regarded as including such equivalent construction to the extent that they do not depart from the essence and scope of the present invention.

Brief description of the drawings

Fig.1 is a block diagram of the automated system of oxygen delivery in accordance with one embodiment of the present invention.

Fig.2A is a block diagram of the gas supply mechanism in accordance with one embodiment of the present invention.

Fig.2B is a block diagram of the gas supply mechanism in accordance with another embodiment of the present invention.

Fig.3 is a diagram of the process control of the automated system of oxygen delivery in accordance with one embodiment of the present invention.

Fig.4 is a flow diagram of a process illustrating a method of automated supply the patient with oxygen in accordance with one embodiment of the present invention.

Fig.5 is a flow diagram of a process illustrating a method of automated supply the patient with oxygen in accordance with another embodiment of the present invention.

A detailed description of the invention

The invention is further described with reference to the drawings, in which like numbers everywhere correspond to the same node.

Fig.1 I�is a block diagram of the automated system of oxygen delivery in accordance with one embodiment of the present invention. In General, the automated system 100 of oxygen delivery is controlled programmatically, equipped with servo gas delivery system that provides a full-featured mechanical ventilation support in terms of pressure and volume for neonatal, pediatric and adult patients. More specifically, the automated system 100 of oxygen delivery securely maintains the quantity measured in the bloodstream of the patient's oxygen within a user-selectable range by titration FiO2on the basis of measurements of oxygen. As shown in Fig.1, the automated system 100 of oxygen delivery 10 includes a sensor that measures the amount of oxygen in the bloodstream of the patient, the control subsystem subsystem 20 and 30 Pneumatics.

In one preferred embodiment, the sensor 10 is using the technology selection signal pulse oxymeter sensor Masimo (Masimo Corporation, Irvine, CA), which measures the absorption of light at two different wavelengths, such as waves of red and infrared light, which can be determined the proportion of red blood cells into the optical path, which carry oxygen and, hence, the amount of oxygen in the bloodstream of the patient. In this embodiment of the sensor module 12 is the interface Board Masimo, such as MS 11 MS 13, etc., the sensor�m 10 - pulse oxymeter sensor Masimo, such as LNCS (or LNOP) Adtx, Pdtx, Inf, Neo, NeoPt, etc., which is connected with the control subsystem 20 via the sensor module 12 and auxiliary cables. The sensor module 12 includes a microcontroller, processor, digital signal processing and service electronic circuit that is used to control the active components of the sensor 10, such as red and infrared LEDs, to capture the transducer 10 light signals, to process these signals and generating measurement data and the related sensor status information. Based on these light signals, the sensor module 12 calculates the saturation of peripheral oxygen SPO2in the bloodstream of the patient and the pulse rate of the patient, generates associated with the data SPO2status information, including, for example, perfusion index, an indicator of signal quality, etc., and transmits these data to the control subsystem 20 via the touch interface 14, such as a serial interface RS-232. Alternatively, the sensor module 12 may be directly entered in the control subsystem 20, replacing the touch interface 14.

In this embodiment, the perfusion index is a relative change of optical absorption oxygendemanding of erythrocytes between PE�iodine systole and diastole of the arterial pulse. The measure of signal quality is, overall confidence levels for SpO2and in this embodiment a pulse oximeter indicator of signal quality based on changes in optical absorption, and non cardiac cycle. In addition, the sensor module 12 may identify the artifacts of the measurement or sensor failures, such as optical interference (for example, too much ambient light), electrical interference, the non-detection sensor, the non-sensor, etc., and provide this information on the state of the control subsystem 20. In one embodiment, the sensor module 12 can provide direction to red and infrared plethysmographic signals directly to a touch interface 14 with a specific resolution and frequency signals, such as, for example, 4 bytes/signal and 60 Hz, from which the management subsystem 20 calculated SpO2. These signals can be appropriately processed, averaged, filtered, etc., and be used to provide a measure of perfusion index, signal quality, a variety of signal parameters, etc.

In yet another embodiment, the sensor 10 is a percutaneous sensor gas pressure, such as, for example. Radiometer TCM 4 or transcutaneous monitor TSM (Radiometer Medical ApS, Bronshoj, Denmark), which directly�DNAs measures the partial pressure of oxygen in arterial blood, that is, in the blood of the surface of the capillary blood vessels, using a gas permeable membrane that is placed in close contact with the skin. The membrane is heated to a temperature between 38°C and 40°C, to cause dilation of superficial blood vessels, and the oxygen can diffuse through the skin surface and the permeable membrane until such time as the partial pressure of oxygen in the sensor will not come into equilibrium with the partial pressure of oxygen in the blood. Percutaneous pressure sensor includes an electrochemical cell with silver and platinum electrodes and a reservoir containing dissolved chemical reagents that are capable of direct detection of oxygen and carbon dioxide dissolved in the blood. Provided by such a sensor measurement data include measurements of arterial oxygen partial pressure PtcO2and measurement of arterial partial pressure of carbon dioxide PtcCO2, while the status information may include data on dissipation, temperature sensor and skin perfusion. These data can be supplemented with auxiliary information obtained by the pulse oximeter. In this embodiment of the transcutaneous sensor gas pressure sensor module 12 may be provided in the form of an independent module or as a component in control�flausa subsystem 20.

In yet another embodiment, the sensor 10 is an invasive catheter Hematology analyzer, such as, for example, Diametric Neocath, Paratrend or intra-arterial monitor Neotrend that is injected into a blood vessel and directly determines the various chemical properties of blood, such as the content of O2WITH2, pH, etc., using chemoluminescent materials that either generate or absorb light with specific wavelengths, depending on the number of molecules dissolved near the sensor. Then the light through the optical fiber in the catheter is transmitted to the external control device, such as sensor module 12. Ensure that sensor data measurements include dissolved in the blood oxygen RHO2dissolved in the blood carbon dioxide RDF2the acidity of the blood pH and blood temperature. In this embodiment of the transcutaneous sensor gas pressure sensor module 12 may be provided in the form of an independent module or as a component in the control subsystem 20.

The control subsystem 20 monitors the execution of all functions of ventilation, processing sensor data, calculate the gas parameters, monitor and ensure the user interface. In one preferred embodiment of the control subsystem 20 includes, among other things, a display 24, one renesola devices 26 input the touch interface 14, the interface 28 Pneumatics subsystem and one or more attached to a processor 22. For example, the display 24 may be a having a back-lit liquid crystal display (LCD) display with 12.1-inch active-matrix with a resolution of 800x600, which provides the user with a graphical user interface (GUI) that includes all adjustable controls and signaling devices, and also displays the timing diagram, lines of communication, digital monitors, and emergency. The device 26 may include an analog resistive touch screen overlay for display 24, a set of membrane panel key(s), optical encoder, etc. Software executable by the processor 22, interacts with a touch screen overlay to provide the user with a set of context-sensitive soft keys, while panel membrane keys provides a set of hardware buttons with a pre-defined constant functions. For example, the user can select a certain function of the display and pressing using an optical encoder to adjust specific settings that are accepted or canceled by pressing the appropriate button. The interface subsystem 28 Pneumatics suasive�Xia interface 34 of the management subsystem, placed in the subsystem 30 Pneumatics, to send commands and receive data from subsystem 30 Pneumatics, for example, by high-speed serial communication.

The processor 22 is basically controls the concentration delivered to the patient oxygen, based on the desired user input concentration of arterial oxygen and obtained from the sensor 10 measurement data and status information.

For example, the processor 22 performs the calculations of gas parameters, controls all valves, solenoids and electronics Pneumatics subsystem are required to supply the patient with a gas mixture. In addition, the CPU 22 controls the GUI, including the update of the display 24, monitors keystrokes membrane keypad, analog resistive touch screen and optical activity of the encoding device. Executed by the processor 22 ways of regulation of the gas mixture are discussed in more detail below.

Subsystem 30 Pneumatics contains all mechanical valves, sensors, microcontrollers, analog electronics, power source, etc., necessary for receiving, processing and delivering the gaseous mixture to the patient. In one preferred embodiment, the subsystem 30 includes Pneumatics, among other things, the interface 34 of the management subsystem, one or more possible microcontroller� (not shown), the inlet 36 of oxygen, the inlet 37 of the air, edition 38 for gaseous mixtures, it is possible to inlet 39 for exhaled air and the mechanism 40 is gas that mixes oxygen and air for the formation of a gaseous mixture having delivered oxygen concentration, and then delivers the gaseous mixture to the patient via the release of 38 for gaseous mixtures. In one embodiment, the subsystem 30 Pneumatics receives oxygen through the inlet 36 for oxygen and compressed air through the inlet 37 for air filters and mixes these gases through a gas mixing unit and then supplies the gaseous mixture with a suitable pressure or volume through 38 for release of gaseous mixture. In another embodiment, the subsystem 30 Pneumatics receives oxygen through the inlet 36 for oxygen and compressed air through the inlet 37 for air filters these gases and then sends the calculated air flow is calculated and the flow of oxygen to release to the patient so as to provide a suitable pressure or volume of a gaseous mixture with a predetermined proportion of oxygen FiO2through the release of 38 for gaseous mixtures. In the next incarnation subsystem 30 Pneumatics gets oxygen, the pre-mixed with an additional gas, such as nitrogen, helium, oxygen-helium mixture 80/20, etc., through the inlet 37 to the air and control subsystem regulates 0 mixing, the amount of the filing, tracking and alarm volumes, as well as monitoring and alerts about the metric FiO2based on the properties of the incoming air / additional gas. Can also be provided with heated expiratory system, spray gun and compressor.

In one embodiment, the management subsystem subsystem 20 and 30 Pneumatics, respectively, are located within individual hardware modules or housings, while in another embodiment, the management subsystem subsystem 20 and 30 Pneumatics are placed within a single module or housing.

Fig.2A is a block diagram of the gas supply mechanism in accordance with one embodiment of the present invention. In this embodiment, the mechanism 40 is gas includes, among other things, Pneumatics inlet 41, a mixer 42 of oxygen, accumulation system 43, valve 44 controlling the flow sensor 45 flow control, pressure reducing and pressure relief valve and discharge pipe 46. In one embodiment, the compressor 49 supplies additional or replacement air to the mixer 42 of oxygen. Pneumatic inlet 41 receives the net O2and the air or mixture of air and more gas, provides additional filtering and regulates the flow of O2and air to the mixer 42 of oxygen that mixes O2Vozduh to the desired concentration determined by commands received from the control subsystem 20. Storage system 43 is used for peak discharge values. The valve 44 of flow control in General, controls the feed rate of the patient gaseous mixture, and the sensor 45 flow provides the control subsystem 20 information about the actual flow of inspiration. Gas delivered to the patient through the relief valve and discharge pipe 46.

In one embodiment Pneumatics 41 at the inlet includes a conduit with smart, relevant standards of a particular country or region fittings for compressed (for example, from 20 to 80 psi) of air and oxygen, hyperfine input filters that remove aerosols and particulate pollutants from the incoming gas, pressure sensors, which detect the leakage of each of the incoming gas, a check valve at the air inlet and the control switch of oxygen at the inlet of oxygen. Switch oxygen acts as a shut-off valve for oxygen when there is power, and as a check valve when energized. Located further in the combination of airflow and switch O2can also be used to ensure a balanced supply pressure in the gas mixing system. The flow regulator air� reduces the pressure air supply to 11.1 pounds per square inch and directs the switch O2thus, in order to monitor this pressure. When provided by a compressor 49, the air supply pressure is adjustable from about 5 psi to about 10 psi, or preferably from about 6 psi to about 9.5 psi.

When the pressure of the incoming air drops below about 20 psi, the compressor 49 is activated to automatically direct the air to the mixer 42 of oxygen. When the compressor 49 is not provided, rocker opens the solenoid for supplying to the control of air flow of compressed oxygen, allowing the airflow to submit adjusted with O2the pressure to switch O2. In addition, the mixer 42 oxygen simultaneously moves to the position 100% O2the way to preserve full supplied to the patient flow. Similarly, when the oxygen pressure falls below about 20 psi, reversible solenoid remains closed, the solenoid switch of oxygen is disconnected from power, the mixer is moved to 21% O2and adjusted the air pressure supply to the mixer 42 of 100% oxygen of the air.

The mixer 42 oxygen supply receives gases from Pneumatics 41 of the inlet and mixes the two gases to a certain �of elicina, determined by the management subsystem 20. In one embodiment of the mixer 42 includes oxygen valve, stepper motor and the electronic control unit.

The drive 43 is connected with the exhaust pipe oxygen mixer 42 with the help of a controllable valve with a large lumen, connected in parallel with a check valve. The storage device 43 stores mixed gas from the mixer 42 of oxygen, which increases the efficiency of the system and provides tidal volume in accordance with the respiratory cycles and flow of peak flow at a relatively reduced pressure, and the result are the preferred lower energy requirements of the system. The gas pressure in the drive pulses between about 2 psi and about 12 psi depending on tidal volume and needs in peak discharges. Bypass port drive lets you leave your drive approximately 6 liters of gas per minute, thereby providing a stable mixture of O2even without the use of a flow control valve. Safety relief valve provides protection against pressure above about 12 psi. Periodically, at specified intervals of time can be activated solenoid water drainage for release of the corresponding quantity of gas from the accumulator 43, Thu�would blow out all possible accumulated moisture. After the drive later in the attached controller to provide a source of regulated pressure Pneumatics. For measurement of the delivered FiO2sensor O2selected exhaust flow of 0.1 l/min In another embodiment, the storage device 43 may be excluded from the mechanism 40 gas flow.

System flow control provides the desired feed rate of the gaseous mixture to the patient and includes a valve 44 controlling the flow sensor 45 flow rate and gas temperature sensor and the pressure sensor in pneumatic system. The compressed gas stored in the storage device 43, nourishes the valve 44, the flow regulation administered by the control subsystem 20 via the interface 34 of the management subsystem. The flow sensor 45 together with the gas temperature sensor and pressure sensors in the pneumatic system provides feedback to the management subsystem 20. At certain intervals of time management subsystem 20 takes readings of the sensors, performs calculations, and issues a command that sets the position regulating flow valve 44. The control subsystem 20 produces an adjustment in flow rate, gas temperature, gas density and pressure. Proportional to the pressure drop of the flow is measured using the pressure sensor, in a suitable manner when using nullable odgovori more automatically installed on the zero solenoids. It is important that when a patient is a newborn, return/relief valve is in the closed state and the gaseous mixture continues to flow from the mixer 42 of oxygen to the storage device 43 to provide the desired minimum flow through the mixer, but the gaseous mixture does not flow back from the storage device 43 to the circuit of the patient. This is preferably minimizes the time required to make changes in a set up issue for the patient's share of the oxygen content.

A safety pressure relief valve and discharge pipe 46 include, among other things, the three-way pressure relief solenoid valve, safety valve, controlled by a high / pressure below the ambient pressure, and a check valve. A safety pressure relief valve and discharge pipe 46 prevent development in the breathing loop pressure and allow the patient to breathe ambient air while warning signal "safety valve open. Safe state can also be activated in the complete cessation of gas supply or power outages. A safety relief valve is a mechanical safety valve which prevents excess pressure of a certain value with a maximum exp�house gas about 150 l/min. This safety valve is operated by a solenoid and the loss of power supply or alarm "vent inop" ("ventilation does not work") pressure relief solenoid is deactivated, forcing the valve pressure below ambient to open, allowing the patient to breathe gas from the environment. In this case, the check valve helps to ensure that the patient breathed through the valve pressure below ambient and exhaled through the exhalation valve, avoiding, thus, the return of the patient's breathing.

In one preferred embodiment of the delivered gas is forcibly supplied to the patient by means of closing controlled by a servo valve exhalation. The patient is given the opportunity to exhale through the exhalation valve, which also supports the base pressure or PEEP (positive pressure at the end of exhalation). Exhaled patient gas is discharged through the pipe expiratory circuit of the patient and in one embodiment is returned to the subsystem 30 Pneumatics through the inlet 39 of the exhalation passes through the heated expiratory filter external to the sensor stream, and then through the exhalation valve in the surrounding atmosphere.

Preferably the volume of gas may be monitored at the outlet of the exhalation device or tee in a patient's breathing circuit that allows a more precise control of patie�, especially in the case of infants, providing easy handling with the flow sensor in the pipe exhale, protected the heated filter that is preferred in the adult ICU (intensive care unit). This can be measured tracheal and esophageal pressure. In the breathing loop to the tee of the patient may be possible sensor attached WITH2such as, for example, a sensor WITH2Novametrix Capnostat 5 Mainstream attached to the control subsystem 20 via serial communication port to control the pressure of the exhaled at the end of a quiet expiration2and obtaining a timing diagram of the pressure of exhaled CO2. When used in conjunction with a tee flow sensor in the breathing loop is allowed compensation changes in lung volume at the pressure change, the timing diagram of pressure FROM2can also be used to produce secondary monitors.

Fig.2 is a block diagram of the gas supply mechanism in accordance with another embodiment of the present invention. In this embodiment, the mechanism 50 gas includes, among other things, Pneumatics 51 intake of oxygen, the device 52 flow control of oxygen, Pneumatics 53 air intake device 54 flow control air manifold 57 mix gases sensor 55 regulirovaniya pressure reducing and pressure relief valve, and discharge pipe 56. Pneumatics 51 intake of oxygen gets pure O2provides additional filtering and O2to the controller 52 of the flow of oxygen. Pneumatics 53 air intake gets clean air or mixture of air and more gas, provides additional filtering and provides air supply to the controller 54 of the air flow. In one embodiment, the controller 54 of the air flow regulating valve is controlled by a servo, while in another embodiment the controller 54 of the air flow is a variable speed fan or pump. The controller 52 of the flow of oxygen and the controller 54 of the air flow to manage the flow of oxygen and air to be sent to the collector 57 of mixing gases in a simple ratio, determined by commands received from the control subsystem 20. The sensor 55 flow provides the control subsystem 20 information about the actual flow of inspiration and gas delivered to the patient through the relief valve and discharge pipe 56. In this embodiment, the proportion of oxygen in the delivered gas mixture depends on the regulatory costs of oxygen and air (Qoxygen and Qair, respectively) as presented in Equation (1):

%O= (100*Qoxygen+21*Qair)(Qoxygen+Qair)=21+79Qoxygen(Qoxygen+Qair)(1)

Fig.2C is a block diagram of the gas supply mechanism in accordance with another embodiment of the present invention. In this embodiment, the mechanism 60 gas includes, among other things, Pneumatics 61 intake of oxygen, the device 62 flow control of oxygen, Pneumatics 63 air intake manifold 67 gas mixing device 68 regulation of the gas flow, the sensor 65 flow control and pressure relief valve and discharge pipe 66. Pneumatics 63 air intake gets clean air or mixture of air and more gas, provides additional filtering and provides air supply to the manifold 67 gas mixing. Pneumatics 61 intake of oxygen gets pure O2provides additional filtering and O 2to the controller 62 of oxygen consumption, which controls the flow of oxygen sent to the collector 67 of mixing gases according to the commands received from the control subsystem 20. The mixture of gases is then sent to the controller 68 of the gas flow, which controls the flow delivered to the patient mixed gas according to the commands received from the control subsystem 20. In one preferred embodiment, the controller 68 of the gas flow is a fan with variable speed or pump. The sensor 65 flow provides the control subsystem 20 information about the actual flow of inspiration and gas delivered to the patient through the relief valve and discharge pipe 66. In this embodiment, the proportion of oxygen in the delivered gas mixture depends on the adjustment of the flow rate of oxygen and mixed gas (Qoxygen and Qgas, respectively) as presented in Equation (2):

%O2=(100*Qoxygen+21*(Qgas-Qoxygen))Qgas=21+79Qoxyg enQgas(2)

Fig.3 is a diagram of the process control of the automated system of oxygen delivery in accordance with one embodiment of the present invention. In General, the automated system 100 shipping regulates oxygen delivered to a patient FiO2way feedback based on measurements of oxygen concentration in the bloodstream of the patient and the desired oxygen concentration set by the user. The process 90 of regulation FiO2using the feedback is implemented using software and/or firmware, executable by one or more processors 22, and includes obtaining input data 82 from the operator using the device(s) 26 input, receiving sensory data 80 from the sensor module 12 or directly from the sensor 10 and the sending of commands to the mechanism 40 of the gas supply and other components in the pneumatic module 30 required for the regulation delivered to a patient FiO2.

Entered by operator data 82 include, among other things, data on the thresholds of sensitivity of the sensor, the desired percentage FiO2and the lower threshold value FiO2corresponding to n�the most lowest acceptable value FiO 2. Sensory data 80 includes measurement data of the sensor and associated status information, such as, for example, indicators of signal quality, etc., In one preferred embodiment, the sensor 10 is a pulse oximeter and sensor data 80 includes measuring SpO2the perfusion index, indicators of signal quality, displaying artifacts of measurement, sensor failures, etc., Entered by operator data 82, respectively, include the lower threshold SpO2corresponding to the lower boundary of the specified valid range of values SpO2and the upper threshold SpO2corresponding to the upper limit of the predetermined allowable range of values SpO2.

The process 90 of regulation FiO2feedback provides filtering 92 sensory data, regulation 94 FiO2and training 96 output. In the filtration stage 92 of sensory data to obtain measurement data representing the concentration of oxygen in the bloodstream of the patient, associated status information and data about the sensitivity threshold of the sensor, processing the sensor data and determines whether such measurement data is accurate. In one embodiment according to the measurements is determined by the status of Arsenii that determines the level of oxygen in the bloodstream of a patient as pertaining to low di�the range, the normal range or high range. When regulating 94 FiO2obtain the processed sensor data and data on the status of Arsenii, the thresholds of sensitivity of the sensor, the desired percentage FiO2and lower threshold FiO2and determine the amount delivered FiO2and other operating parameters for pneumatic module 30, such as the flow rate of the gaseous mixture, the supply pressure, etc., When preparing 96 output data is the conversion of data delivered by FiO2and operating parameters on special teams for the mechanism 40 of the gas supply and other components of the module 30 Pneumatics.

In one preferred embodiment regulation 94 FiO2controls deliver FiO2based on the desired concentration of oxygen measured by the oxygen concentration, basic level FiO2and FiO2component status examie. Baseline FiO2represents the average level FiO2necessary to maintain the patient in a stable state normoxia, while FiO2component status examie provides various control algorithms, such as proportional, integral, proportional-integral, etc.

Preferably, the regulation 94 FiO2ensures that �oncentrate of oxygen in the bloodstream of the patient does not fall below the lower threshold or above the upper threshold in the cases when touch data is unreliable. This is not only based on representative measurements of oxygen concentration, but also, importantly, on the related sensor status information. For example, despite the fact that the touch module 12 can present some measurement values that are within the range of normal concentrations of oxygen, in practice, these data provide a touch module 12 to one or more related figures of merit can be considered not credible.

In the embodiment of the pulse oximeter during the filtration 92 sensory data receive information about the lower and upper thresholds SO2p and check the measured perfusion index SO2p, an indicator of signal quality indicators measurement artifacts, sensor failures, etc., to determine whether the measurement of SO2p reliable, and saves data for SO2p for one or more seconds. From the measurement data SO2p and thresholds SO2p is determined by the status of Arsenii. In one preferred embodiment is determined by the condition of hypoxemia (low range), if the dimension of SO2p is smaller than the lower threshold SO2p, the state of hyperoxemia (upper range) is determined if the measurement of SO2p is above the upper threshold SO 2p, and the condition of normoxia (normal range) is determined when the measurement of SO2p is located between the lower and upper thresholds SO2p. While specific values for the lower and upper threshold values SpO2prescribed by the attending physician on the basis of specific needs of the patient, usually these thresholds are in the range from 80% to 100%. For example, the lower threshold SO2p can be set equal to 87%, whereas the value of the upper threshold SpO2can reach 93%. When you define can be used the most recent measurements SpO2or, alternatively, may be statistically processed by a number of previous measurements SpO2and when you define can be used resulting value (e.g. the average value of the sample arithmetic mean, etc.).

In this embodiment regulation 94 FiO2obtain the processed measurement data SpO2, perfusion index, signal quality, etc., and data on the status of Arsenii, thresholds SpO2desirable percentage content FiO2and lower threshold FiO2in compliance with which is calculated deliver FiO2and other operating parameters of the pneumatic module 30. Though the specific value of the lower threshold FiO2prescribes the attending physician�m on the basis of specific needs of the patient, usually this threshold is in the range from 21% to 100%, averaging 40%. As for the lower threshold FiO2if the calculated value delivered FiO2is less than the lower threshold FiO2the regulation 94 FiO2sets the index delivered FiO2at the lower threshold FiO2. Similarly, with regard to thresholds SPO2if the measured SPO2is less than the lower threshold SPO2regulation 94 FiO2increases the amount delivered FiO2and if the measured value SPO2exceeds the upper threshold SPO2regulation 94 FiO2reduce the amount of delivered FiO2. As for the information of sensor status, if the perfusion index is below the threshold perfusion, comprising, for example, of 0.3%, regulation 94 FiO2sets deliver FiO2equal to a predetermined value. Similarly, if the quality of the signal is less than the threshold signal quality, making, for example, 0,3, regulation 94 FiO2sets deliver FiO2equal to the specified value and possibly activates an audible or visual alarms. Such a mode may be adopted for indicators and artifacts from�ereni, data on failures of the sensor, etc.

In the next incarnation for the purpose of linearization of action for the regulation of the pressure of oxygen in the blood, changes in FiO2in States normoxia and hypoxemia can be computed from theoretical data on the oxygen pressure. In this embodiment regulation 94 FiO2initially applies the transformation values SpO2to normalize their frequency distribution, and then applies the converted values SpO2one or more linear filters. One such transformation is the inverse transform of the curve of oxyhemoglobin saturation.

Fig.4 is a flow diagram illustrating a method 200 for automated delivery of oxygen to the patient in accordance with one embodiment of the present invention.

Initially, the user receives (210) the desired oxygen concentration. As discussed above, the user can enter a desired concentration of oxygen, such as, for example, the desired percentage FiO2with the help of the device(s) 26 input and display 24.

Receiving (220) touch data from the touch module 12 or directly from the sensor 10 through the touch interface 14. As discussed above, sensor data includes a measurement of the amount of oxygen in the bloodstream of the patient and associated with from�erenee status information, such as, for example, measurements of saturation of peripheral oxygen, measurement of arterial oxygen partial pressure, measurement of blood levels of dissolved oxygen, perfusion index, an indicator of signal quality, artifacts, measurements, information about the state of the sensor, etc.

Then there is the determining (230) the reliability of the measurement results on the basis of the obtained measurement values and status information. As discussed above, when filtering 92 sensory data to obtain measurement data representing the concentration of oxygen in the bloodstream of the patient, associated status information and data about the sensitivity threshold of the sensor, processing the sensor data and determines whether such measurement data is valid.

If the measurement results are evaluated as significant (240), then delivered to the patient FiO2adjustable (250) based on the desired concentration of oxygen and the results of such measurements. As discussed above, regulation 94 FiO2obtain the processed touch data, the thresholds of sensitivity of the sensor and the desired percentage FiO2and regulate the flow FiO2based on the desired percentage FiO2and the measured oxygen concentration.

On the other hand, if resultativity not recognized as valid (240), regulation 94 FiO2configures (260) feeding the patient FiO2in accordance with a predetermined value.

Then the patient is sent (270) the gaseous mixture with the established percentages FiO2the oxygen.

Fig.5 is a flow diagram illustrating a method 2O2automated supply the patient's breathing gas mixture with calculated percentages of oxygen, in accordance with another embodiment of the present invention.

Initially, the user receives (210) the desired oxygen concentration. As discussed above, the user can enter a desired concentration of oxygen, such as, for example, the desired percentage FiO2with the help of the device(s) 26 input and display 24.

Receiving (222) pulse oxymeter data is produced from the pulse oxymeter module or directly from the pulse oximeter using the touch interface 14. As discussed above, pulse oxymeter data include measurement of saturation of peripheral oxygen SPO2in the bloodstream of the patient, perfusion index, an indicator of signal quality and may display artifacts of the measurement, the state of the pulse oximeter, etc.

Then is (232) validation of measurement SPO2based on the magnitude of the measured SPO2and at least �defined from the perfusion index, the quality indicator signal, and possibly display(nd) measurement artifacts, the state of the pulse oximeter, etc., As discussed above, when filtering 92 sensory data to obtain measurement data SPO2, perfusion index, signal quality, etc., as well as data on threshold values SPO2, a data processing and determines whether such measurement data is accurate. Filtering 92 sensory data based on the measured SPO2also defines the status of Arsenii.

If measurements SPO2are assessed as significant (242), then the measured SPO2classified by ranges of hypoxaemia, normoxia or hyperoxemia and regulation (254) delivered to a patient FiO2based on the desired percentage FiO2the measurement results of the SPO2and in the corresponding band. As discussed above, regulation 94 FiO2get information about the status of Arsenii, the threshold for FiO2the results of processing SPO2threshold values SPO2and desirable percentage FiO2and regulate the value delivered FiO2based on the desired percentage FiO2, the measurement data SPO2and in the corresponding band. Regulation 94 FiO2ensures to deliver FiO2was not below the threshold�howl value FiO 2that increases the supply FiO2if the measurement SPO2be below the lower threshold SPO2and reduces FiO2if the measurement SPO2exceed the upper threshold SPO2.

On the other hand, if the measurement results SpO2not recognized as valid (242), regulation 94 FiO2configures (260) delivered to a patient FiO2in accordance with a predetermined value.

Then oxygen is supplied (270) to the patient.

From this detailed description it is clear many of the features and advantages of this invention and, therefore, it is intended to cover in accordance with the appended claims all such features and advantages of the invention that are within the essence and scope of the invention. In addition, since the experts in this area can be easily implemented numerous modifications and changes that limit the invention to precise, described and explained here design and operations is undesirable, and accordingly, all suitable modifications and equivalents may be considered as being within the scope of this invention.

1. An automated system to deliver oxygen containing:
the sensor measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
subsystem Pneumatics, incl�General:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered oxygen concentration, and for delivering the gaseous mixture to the patient; and
a management subsystem that is connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
the touch interface is arranged to receive measurement data and status information associated with the measurement data of the sensor, wherein said status information includes a perfusion index that describes the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse, and an indicator of signal quality based on changes in optical absorption of light from said sensor,
the interface of the Pneumatics subsystem to send commands and receive data from subsystem Pneumatics and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control the concentration of oxygen supplied on the basis of the desired concentration of oxygen�and, measurement data and status information.

2. Automated system for delivery of oxygen according to claim 1, in which the air inlet is arranged to receive breathing gas mixture.

3. Automated system for delivery of oxygen according to claim 1, in which the gas supply mechanism configured to control the flow rate and the supply pressure of the gaseous mixture.

4. Automated system for delivery of oxygen according to claim 1, in which the delivered oxygen concentration expressed as a fraction of inhaled oxygen FiO2.

5. Automated system for delivery of oxygen according to claim 4, in which deliver FiO2has a value not lower than the threshold values Fi.

6. Automated system for delivery of oxygen according to claim 4, in which the sensor data include measurements of saturation of peripheral oxygen, SpO2.

7. Automated system of oxygen delivery according to claim 6, in which the processor is arranged to determine reliably whether the measurement SpO2or false, based on the magnitude of the measured SPO2and perfusion index, measuring SpO2is defined as false, when (i) the measured SpO2is within the range between the lower threshold SpO2and upper threshold SpO2and (ii) the perfusion index is below the threshold� perfusion, and in which the processor is arranged to control the supplied oxygen concentration based on SpO2, perfusion index and the index of the quality of the signal.

8. Automated system for delivery of oxygen according to claim 7, in which the processor is arranged to increase the FiO2if the measurement data SpO2is below the lower threshold SpO2and arranged to reduce the flow FiO2if the measurement data SpO2exceeds the upper threshold SPO2.

9. Automated system for delivery of oxygen according to claim 7, in which the processor is arranged to install FiO2equal to a predetermined value, if the perfusion index is below the threshold perfusion.

10. Automated system for delivery of oxygen according to claim 7, in which the processor is arranged to install FiO2equal to a predetermined value, if the indicator of the signal quality falls below a threshold signal quality.

11. Automated system for delivery of oxygen according to claim 10, in which the processor is configured to initiate at least one of an audible alert and a visual alert signal if the signal quality falls below a threshold signal quality

12. The functions are fully automated� system of oxygen delivery according to claim 4, further comprising:
percutaneous pressure sensor connected with said sensor interface and configured to supply additional sensor data mentioned in the touch interface, wherein the additional sensor data include:
measurement of partial pressure of arterial oxygen PtcO2and
measurement of partial pressure of arterial carbon dioxide PtcCO2.

13. Automated system for delivery of oxygen according to claim 4, in which the sensor is an invasive catheter Hematology analyzer and sensor data include measurements of dissolved oxygen in your blood, pCO2measuring the pH of blood pH and temperature measurements of blood.

14. An automated system to deliver oxygen containing:
pulse oxymeter sensor for measuring the saturation of the blood flow of the patient's peripheral oxygen SpO2;
the Pneumatics subsystem, including:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered the fraction of inhaled oxygen FiO2and for delivering the gaseous mixture to the patient; and
administering more than�him, connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
touch interface for receiving measurement data and status information associated with the measurement data of the sensor, wherein the status information includes a perfusion index and an indicator of signal quality,
the interface of the Pneumatics subsystem to send commands and receive data from subsystem Pneumatics and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control FiO2on the basis of the desired concentration of oxygen, SpO2, perfusion index and quality index signal and for establishing FiO2,equal to a predetermined value, if the index of perfusion falls below the threshold perfusion or measure of signal quality falls below a threshold signal quality.

15. Automated system for delivery of oxygen according to claim 14, in which the air inlet is arranged to receive breathing gas mixture.

16. Automated system for delivery of oxygen according to claim 14 in which the feed gas is arranged to control the flow rate and the supply pressure of the gaseous mixture.

17. Automated system DOS�avki oxygen according to claim 14, in which FiO2has a value not lower than the threshold FiO2.

18. Automated system for delivery of oxygen according to claim 14 in which the processor is arranged to increase the FiO2if the measurement data SpO2is below the lower threshold SpO2and arranged to reduce FiO2if the measurement data SpO2exceeds the upper threshold SPO2.

19. Automated system for delivery of oxygen according to claim 14, in which the perfusion index is a relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse.

20. Automated system for delivery of oxygen according to claim 14, in which the quality indicator signal provides a measure of confidence for SpO2.

21. Automated system for delivery of oxygen according to claim 20, in which an indicator of signal quality based on changes in optical absorption oxygendemanding of red blood cells.

22. Automatic delivery of oxygen to a patient, comprising: a sensor for measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
the Pneumatics subsystem, including:
the intake of oxygen, air intake, release of gaseous mixture,
means for mixing oxygen and air d�I formation of a gaseous mixture, having delivered oxygen concentration, and
the vehicle delivering the gaseous mixture to the patient; and
the control subsystem connected to a device for measuring the amount of oxygen and Pneumatics subsystem, including:
an input device for obtaining the desired concentration of oxygen in the bloodstream of the patient;
the first interface, configured to obtain measurement data and status information associated with the measurement data of the sensor for measuring the amount of oxygen, wherein the status information includes a perfusion index that describes the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse, and an indicator of signal quality based on changes in optical absorption of light from said sensor,
a second interface to send commands and receive data from subsystem Pneumatics, and
a processor coupled to the first interface and the second interface, to control the feed of the oxygen concentration on the basis of the desired concentration of oxygen, the measurement data and status information.

23. An automated system to deliver oxygen containing:
the sensor measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
the Pneumatics subsystem, vkluchayu�:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered oxygen concentration, and for delivering the gaseous mixture to the patient; and
a management subsystem that is connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
the touch interface is arranged to receive measurement data and status information associated with the measurement data of the sensor, wherein said measurement data include measurements of saturation of peripheral oxygen, SpO2referred to the status information includes a perfusion index that describes the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse, and an indicator of signal quality based on at least one of the following: current changes in the optical absorption of light from said sensor while it is attached to the patient, electrical or optical interference,
the interface of the Pneumatics subsystem for sending commands and receiving dannyjt Pneumatics subsystem and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control the concentration of oxygen supplied on the basis of the desired concentration of oxygen, the measurement data and status information, for inclusion of indicator of the quality of the signal processor provides a confidence score for SpO2the measurements.

24. An automated system to deliver oxygen containing:
pulse oxymeter sensor for measuring the saturation of the blood flow of the patient's peripheral oxygen SpO2;
the Pneumatics subsystem, including:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered the fraction of inhaled oxygen FiO2and for delivering the gaseous mixture to the patient; and
a management subsystem that is connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
touch interface for receiving SpO2measurements and status information associated with the measurement data of the sensor, and the status of the VC�uchet the perfusion index, describing the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse, and an indicator of signal quality, based on current changes in the optical absorption of light from said sensor while it is attached to the patient, and changes associated or affiliated with cardiac cycle, and the indicator of signal quality processor provides a confidence score for SpO2measure,
the interface of the Pneumatics subsystem to send commands and receive data from subsystem Pneumatics and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control FiO2on the basis of the desired concentration of oxygen, SpO2, perfusion index and quality index signal and for establishing FiO2,equal to a predetermined value, if the index of perfusion falls below the threshold perfusion or measure of signal quality falls below a threshold signal quality.

25. Automatic delivery of oxygen to a patient, comprising:
a means for measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
the Pneumatics subsystem, including:
the intake of oxygen, air inlet, a gaseous release with�art thou,
means for mixing oxygen and air for the formation of a gaseous mixture having delivered oxygen concentration, and
the vehicle delivering the gaseous mixture to the patient; and
the control subsystem connected to a device, for measuring the amount of oxygen and Pneumatics subsystem, including:
an input device for obtaining the desired concentration of oxygen in the bloodstream of the patient;
the first interface, configured to obtain measurement data and status information associated with the measurement data of the sensor for measuring the amount of oxygen, wherein said measurement data include measurements of saturation of peripheral oxygen, SpO2referred to the status information includes a perfusion index that describes the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse, and an indicator of signal quality, based on current changes in the optical absorption of light from said sensor while it is attached to the patient, and changes associated or affiliated with cardiac cycle,
a second interface to send commands and receive data from subsystem Pneumatics, and
a processor coupled to the first interface and the second interface, to control the feed concentration �of ikorodu based on the desired concentration of oxygen, measurement data and status information, for inclusion of indicator of the quality of the signal processor provides a confidence score for SpO2the measurements.

26. An automated system to deliver oxygen containing:
the sensor measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
the Pneumatics subsystem, including:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered oxygen concentration, and for delivering the gaseous mixture to the patient; and
a management subsystem that is connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
the touch interface is arranged to receive measurement data and status information associated with the measurement data of the sensor, wherein said measurement data include measurements of saturation of peripheral oxygen, SpO2referred to the status information includes an indicator of signal quality based on at least one of the following: current changes �pricescope absorption of light from said sensor, while it is attached to the patient, electrical or optical interference,
the interface of the Pneumatics subsystem to send commands and receive data from subsystem Pneumatics and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control the concentration of oxygen supplied on the basis of the desired concentration of oxygen, the measurement data and status information, for inclusion of indicator of the quality of the signal processor provides a confidence score for SpO2the measurements.

27. An automated system to deliver oxygen containing:
the sensor measuring the amount of oxygen in the bloodstream of a patient containing a pulse oximeter;
the Pneumatics subsystem, including:
the intake of oxygen, air intake, release of gaseous mixture and
the gas supply mechanism connected to the intake of oxygen, the air intake and the release of gaseous mixtures, for mixing oxygen and air with the formation of a gaseous mixture having delivered oxygen concentration, and for delivering the gaseous mixture to the patient; and
a management subsystem that is connected to the sensor and the Pneumatics subsystem, including:
an input device designed to produce the desired concentration of oxygen in the bloodstream of the patient,
Saint�ornago interface, configured to obtain measurement data and status information associated with the measurement data of the sensor, wherein said measurement data include measurements of saturation of peripheral oxygen, SpO2referred to the status information includes a perfusion index that describes the relative change of optical absorption oxygendemanding of erythrocytes between systole and diastole of the arterial pulse,
the interface of the Pneumatics subsystem to send commands and receive data from subsystem Pneumatics and
a processor coupled to the input device, a touch interface and subsystem interface Pneumatics to control the concentration of oxygen supplied on the basis of the desired concentration of oxygen, the measurement data and status information.



 

Same patents:

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. A method for facilitating expectoration on the basis of oscillation function, which generates an oscillating air flow in the pulmonary system is implemented by means of a device for facilitating expectoration. The above air flow contains an oscillating exhaled and oscillating inhaled air flows. A control unit of the above device comprises first and second identification units and detection units. The first identification unit is used to state if the pulmonary system has completed an inhale to control a valve to be closed to isolate the pulmonary system from the external environment. The second identification unit is used to state if an inner pressure in the pulmonary system is more than a pre-set pressure threshold. The detection unit is used to detect the beginning of the oscillating inhaled air flow to control the valve to be opened for the onset of coughing.

EFFECT: using the group of inventions enables more effective facilitating expectoration.

8 cl, 6 dwg

Laryngeal mask // 2543033

FIELD: medicine.

SUBSTANCE: in laryngeal mask, an O-ring cuff is formed by a U-shaped rim and a part of a large-port gastrodrainage of a special shape, inserting a gastric probe into which forms two auxiliary gaping passes for promoting the free discharge of gastric material or gas found close to an oesophageal funnel to the mouth cavity. The device can additionally comprise reinforcing components are used to avoid respiratory canal occlusion by patient's teeth. The declared laryngeal mask, except for the reinforcing components, represents a monolith and is formed by 1 cycle of injection-moulding machine operation that causes its absolutely low cost price.

EFFECT: laryngeal mask provides high patient's safety ensured by the effective discharge of the gastric material from a glottal aperture and demonstrate the practical simplicity of installation and good hermetism; it can be effectively used in clinical practice even in the patients with a risk of regurgitation and emergency patients.

5 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. A lung compliance is measured in an individual who is at least partially self-ventilating. The quantitative measurement of the lung compliance can represent an assessment, a measurement and/or a rough measurement. The quantitative measurement of the lung compliance can be suspended over common methods and/or systems for the quantitative measurement of the self-ventilating individual's lung compliance; the lung compliance can be quantitatively measured relatively exactly without the use of a force measurement rope or any other external sensing device, which measures a diaphragm muscle pressure directly; the procedure does not require the individual to monitor the diaphragm muscle pressure manually.

EFFECT: quantitative measurement of the lung compliance can be used as an efficient instrument for the individual's health assessment, including detecting fluid retention associated with acute congestive cardiac failure.

15 cl, 4 dwg

FIELD: medicine.

SUBSTANCE: group of inventions refers to medicine. A lung compliance is measured in an individual who is at least partially self-ventilating. The quantitative measurement of the lung compliance can represent an assessment, a measurement and/or a rough measurement. The quantitative measurement of the lung compliance can be suspended over common methods and/or systems for the quantitative measurement of the self-ventilating individual's lung compliance; the lung compliance can be quantitatively measured relatively exactly without the use of a force measurement rope or any other external sensing device, which measures a diaphragm muscle pressure directly; the procedure does not require the individual to monitor the diaphragm muscle pressure manually.

EFFECT: quantitative measurement of the lung compliance can be used as an efficient instrument for the individual's health assessment, including detecting fluid retention associated with acute congestive cardiac failure.

15 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: invention relates to sports medicine. Method includes carrying out interval hypoxic training with breathing gas mixture with simultaneous influence on central nervous system by pulse electric current. Before interval hypoxic training additionally realised is introduction of neuropeptide Semax in dose of two drops in each nasal passage. Interval hypoxic training is carried out at least four times by breathing gas mixture, which contains 9.5% of oxygen. Influence by electric current is realised with pulse duration 0.25-0.28 ms, current power 0.9 mA and frequency of pulses 1250 Hz for 60 minutes.

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1 tbl

FIELD: medicine.

SUBSTANCE: system comprises a breathing device, which is configured to generate a pressurized breathing gas flow into the airway, and respiratory indicators, which cause an individual breath so that the respiratory volume exceeds or is equal to the target respiratory volume. The respiratory indicators comprise the pressurized flow pressure fluctuation. Sensors form one or more output signals transmitting the information related to exhaled gas parameters, which are related to the respiratory volume. A processor is configured to provides modules. The parameter module is configured to determine a respiratory parameter of one or more output signals formed by one or more sensors. The respiratory parameter is either the respiratory volume, or the inhaled gas parameter related to the respiratory volume. The module of congruence is configured to compare the respiratory volume to a threshold, which corresponds to the target respiratory volume. The control module is configured to control the respiratory device to control the respiratory indicators presented for the individual by comparing the respiratory parameters and the threshold by the module of congruence. What is disclosed is a method for respiratory volume control.

EFFECT: providing the relation of the actual and target respiratory volumes.

6 cl, 4 dwg

FIELD: medicine.

SUBSTANCE: group of inventions relates to medical equipment. System for supporting positive pressure in patient's respiratory ways, when patient is breathing, contains respiratory device, made with possibility of controlling gas mixture flow between surrounding atmosphere and, at least, one external orifice of patient's respiratory ways. Respiratory device has first resistance to flow of gas mixture, flowing from surrounding atmosphere into patient's respiratory ways through respiratory device, and second resistance to flow of gas mixture, flowing from patient's respiratory ways into surrounding atmosphere through respiratory device. First resistance is less than second resistance, so that during inhalation gas mixture flows from surrounding atmosphere into patient's respiratory ways through respiratory device without delay. During exhalation second resistance of respiratory device to gas mixture, flowing from patient's respiratory ways into surrounding atmosphere, increases pressure inside patient's respiratory ways. Increased pressure supports patient's respiratory ways. Pressure generator is made with possibility to form flow of compressed respiratory mixture and providing additional support of patient's respiratory ways and is connected with case of respiratory device through contour, which gas mixture channel forms between respiratory device and pressure generator, by which flow of compressed respiratory mixture is supplied from pressure generator into patient's respiratory ways through respiratory device. First resistance constitutes less than approximately 0.025 cm of H2O with flow consumption 30 l/min. Second version of system, which is different in constructive implementation, is disclosed.

EFFECT: providing treatment of sleeping disorders due to creation of resistance to exhalation.

6 cl, 10 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine and can be used in treating the patients with respiratory impairments. A breathing support device comprises a first flow generator an output of which is connected to a patient's breathing system, and a control unit a first input of which is connected to the breathing system, and first and second outputs - to the first flow generator and the breathing system, respectively. The invention provides establishing a second flow generator, a probe inserted into the patient's gastrointestinal tract, a flow sensor and a pressure sensor. The second flow generator connected to the probe inserted into the patient's gastrointestinal tract at an input of which the flow sensor and the pressure sensor are mounted, respectively connected to third and fourth outputs of the control unit a fourth output of which is connected to a pulse oximeter, is connected to the third output of the control unit. The control unit is configured to start a procedure of extrapulmonary administration of oxygen, to determine pressure inside the gastrointestinal tract and controlled reduction of a volumetric flow rate.

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1 dwg

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to anaesthesiology and resuscitation, and can be used in intensive care patients suffering from ventilator-associated pneumonia, or where there is a high risk of development thereof. Stabilising haemodynamics is followed by 8 turns of a patient's body a day. The cycle is started from 08-00: 3 hours on his/her back, 2 hours on his/her side, 2 hours on the other side, 3 hours on his/her back, 6 hours on his/her stomach, 4 hours on his/her back, 2 hours on his/her side, 2 hours on his/her side. The patient's centre of gravity is changed every 2 hours with the patient lying on his/her stomach and back. Propofol is infused at 2-3 mg/kg/hour 20 minutes before the patient is turned on his/her stomach and continued until the patient's position is changed again. A nitroglycerin infusion is started 5 minutes after the patient is turned on his/her back in a dose of 0.5-1.0 mcg/kg/min and continues for 5 hours. An antibacterial preparation is intermittently or microfluid single administered 10 min after the patient is turned on the stomach; observing other rate of administration of the antibacterial preparation, one of the administrations is performed 10 minutes after the patient is turned on the stomach.

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2 cl, 4 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: group of inventions relates to medicine. An electric drive device contains a pump, which contains a rigid cylinder, a piston and, at least, one valve, an electric engine with accurate position control, which has working connection with the said piston for the movement of the said piston in the said cylinder, and a controller, made with a possibility of controlling the electric engine to control the piston position in the cylinder, and in this way to control the respiratory volume of gas, supplied into a patient; and the pressure of gas, supplied in the patient. An apparatus of artificial lung ventilation for supply of gas in the patient and a device for artificial lung ventilation are disclosed.

EFFECT: provision of accurate positioning.

58 cl, 11 dwg

FIELD: medical equipment, applicable for curative prophylaxis and for drug therapy of patients with bronchopulmonary diseases.

SUBSTANCE: the respiratory simulator consists of a mouthpiece - air conduit, casing with a cover, ball and a seat with a central hole making up a check valve. The check valve is made for closing at an expiration, its seat is made inside the casing in the form of a tapered recess in it and a central hole, by-pass channels are additionally made in the casing, a perforated diaphragm for limiting the ball motion is installed under the ball. The by-pass channels are made for adjustment of their area at an expiration or at an inhale, or simultaneously at an expiration and inhale and have a means for adjustment of the area of the by-pass channels. The means for adjustment of the area of the by-pass channels is made in the form of combined radial holes in the casing and ring and/or in the cover, and the cover and/or ring are made for restricted turning relative to the casing. The perforated diaphragm is made for tightening of the ball to the seat.

EFFECT: enhanced efficiency of treatment and simplified construction of the simulator.

14 cl, 16 dwg

FIELD: medicine, respiratory gymnastics.

SUBSTANCE: the present innovation deals with decreasing pulmonary ventilation in patient's endurable volume, controlling the rate for carbon dioxide (CO2) gain in expired air and maintaining the rate of its increase. Moreover, decreased pulmonary ventilation should be performed both at the state of rest and while doing physical loading, one should maintain the rate of CO2 gain in expired air being not above 2 mm mercury column/d at the state of rest and 11 mm mercury column in case physical loading to achieve the level of 32.1 mm mercury column at removing vivid symptoms of the disease and 55 mm mercury column in case of prolonged clinical remission. The method enables to improve therapy of hypocarbic diseases and states due to removing CO2 deficiency.

EFFECT: higher efficiency of therapy.

4 ex, 3 tbl

Air duct device // 2245725

FIELD: medical engineering.

SUBSTANCE: device has curved flexible air-conducting tube and mask segment. The mask segment is shaped to completely fit to the area above the laryngeal orifice. Supporting member has a set of thin flexible ribs branching out from core member stretching from opening area. Having the air duct device mounted, the flexible ribs thrust against the pharyngeal side of cricoid laryngeal cartilage immediately under the esophagus. The mask segment is fixed and thrusts against hard surface without injuring soft esophageal tissues. Versions of present invention differ in means for fixing around the laryngeal orifice of a patient.

EFFECT: enhanced effectiveness of lung ventilation in unconscious state.

14 cl,8 dwg

FIELD: medical engineering.

SUBSTANCE: device has chamber for accumulating carbon dioxide, bite-board and respiratory pipe. The chamber is manufactured as cylinder having conic bases arranged one in the other smoothly movable one relative to each other. The respiratory pipe with bite-board is available on one of external cylinder tips and single-acting valve with choker is available on the other tip allowing rotation for making resistance to expiration. Reservoir for collecting condensate is mounted on cylindrical surface the external cylinder. Pipe for taking air samples is available on distal external cylinder part cone base.

EFFECT: smoothly controlling expiration resistance and carbon dioxide concentration; enhanced effectiveness in separating air flows.

2 dwg, 1 tbl

FIELD: medicine; medical engineering.

SUBSTANCE: method involves applying diaphragmatic respiration with resistance to expiration. Overpressure equal to the resistance is created at inspiration stage. Breathing is carried out in usual pace in alternating A-type cycles as atmospheric air inspiration-expiration and B-type cycles as exhaled gas inspiration-expiration. Time proportion of breathing with exhaled gas to atmospheric air respiration is initially set not greater than 1. The value is gradually increased and respiration depth is reduced as organism adaptation to inhaled oxygen takes place, by increasing the number of B-type cycles and reducing the number of A-type cycles. Device has reservoir attached to mouth with individually selected expiration resistance. The reservoir has features for supporting gas overpressure at inspiration stage equal to one at expiration stage.

EFFECT: enhanced effectiveness of treatment; reduced volition effort required for training; improved operational functionality characteristics.

4 cl, 2 dwg

FIELD: medicine.

SUBSTANCE: method involves introducing catheter via nasal passage into the rhinopharynx and fixed above the entrance to larynx and artificial high frequency jet ventilation is carried out with frequency of 140-150 cycles per min in three stages. Compressed gas working pressure is increased at the first stage to 2.0-2.5 kg of force/cm2 during 7-10 min. The compressed gas working pressure is supported at this level to the moment the clinic manifestations of pulmonary edema being removed and gas exchange normalization being achieved at the second stage. The working pressure is stepwise dropped during 1-2 h at the third stage hold during 10-15 min at each step.

EFFECT: enhanced effectiveness in normalizing hemodynamics.

FIELD: medical equipment.

SUBSTANCE: apparatus for artificial ventilation of lungs and inhalation narcosis can be used for emergency service and has unit for artificial ventilation of lungs, anesthetic unit and unit for alarm switch of anesthetic. Unit for artificial ventilation of lungs has oxygen discharge changing unit, flow meter, pneumatic pulse oscillator, nonreversible pneumatic valve which has access to patient's mask. Anesthetic unit has gas relation changing unit and mixer which has access to patient's mask. Unit for alarm switching anesthetic off is made is made in form of comparison unit which has pneumatic valve mounted in anesthetic feed line, two pneumatic relays and two regulators. Apparatus provides improvement in sensitivity to reduction in oxygen pressure in gas mixture.

EFFECT: widened operational capabilities; simplified exploitation; improved safety.

2 dwg

FIELD: medicine, anesthesiology, resuscitation.

SUBSTANCE: under conditions of artificial pulmonary ventilation at positive pressure at the end of expiration one should set the level of positive pressure at the end of expiration being above against pre-chosen optimal one for 4-8 cm water column. About 10-15 min later one should introduce perfluorocarbon as aerosol with the help of nebulizer for 10-15 min. The innovation enables to introduce perfluorocarbons without depressurization of respiratory contour, decreases damaging impact upon pulmonary parenchyma and, also, reduce invasiveness of the method and decrease expenses of perfluorocarbons.

EFFECT: higher efficiency of therapy.

1 ex

FIELD: medicine.

SUBSTANCE: method involves administering one of antyhypoxidant-antioxidant medicaments on empty stomach in age-specific dose before exposing a patient to cyclic treatment with gas medium. Hypoxi-hypercapnic gas mixture is applied as respiratory gas medium. Then, the patient is moved up for breathing with air-oxygen mixture. TcPO2 and/or SO2 restoration period being over, repeated hypoxi-hypercapnic treatment cycle is applied. The mentioned patient treatment cycles are applied in succession 4-10 times.

EFFECT: enhanced effectiveness of treatment; increased adaptation and reduced risk of side effects.

3 cl, 1 tbl

FIELD: medicine, in particular, exercising of respiratory organs in moderate hypoxia and hypercapnia mode with adjustable resistance to inhalation and expiration.

SUBSTANCE: respiratory exerciser has cylindrical mixing chamber with narrowed upper part, respiratory pipe connected to cylindrical mixing chamber, and bottom with perforations provided in its peripheral portion. Bottom of cylindrical chamber is made doubled. Members of porous material having predetermined density are located within bottom cavity. Central part of bottom is equipped with channel provided within cylindrical chamber and communicating with atmosphere. Inhalation indicator provided within channel is made in the form of movable piston member. Respiratory pipe is equipped with acoustic expiration indicator made in the form of unidirectional resonance whistle. Bottom inner cavity may be provided with additional replaceable loading inserts formed as film disks with openings having predetermined area and flexible loop attached to upper part of cylindrical chamber and having adjustable length.

EFFECT: reduced restrictions in orientation and fixing of exerciser position during usage and provision for indicating quality of expiration cycle.

3 cl, 2 dwg

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