Wound bandage

FIELD: medicine.

SUBSTANCE: invention relates to medical equipment, namely to wound bandages. Wound bandage for wound treatment from medium to high exudation contains carrying layer and absorbing pillow, with absorbing pillow including first absorbing layer, which contains first absorbing material, and different from first layer second absorbing layer, which contains different from first material second absorbing material, with first layer being held at a distance from second layer by at least one third layer, and third layer contains at least one antimicrobial preparation, characterised by the fact that second absorbing material contains fibres, which possess super-high absorption ability, and absorbing pillow additionally contains contacting with wound layer, which is in direct contact with first layer, and contacting with wound layer represents polymer net or perforated polymer film, and antimicrobial means represents elementary silver, silver oxide, silver complex, or silver salt, or their mixtures, and fibres which have super-high absorption ability are obtained from salts of polyacrylic acids or polyacrylates.

EFFECT: application of invention makes it possible to reduce risk of sticking to wound and simultaneously counteract maceration, without loading wound to be treated with excessive biologically active substances.

8 cl, 3 dwg

 

The technical FIELD

The invention relates to wound dressings and their use in the modern treatment of wounds. This invention relates to wound dressings that contain two different from each other absorbent layers, in particular two layers with different absorption capacity, for the treatment of wounds of moderate to high exuding wounds.

PRIOR art

For the treatment of wounds, especially caused by surgical intervention, the market offers many different products. Accordingly, in industry literature and patent information, you can find a lot of suggestions on how and by what means the wound can be treated.

For example, in patent application DE 19727032 A1 describes a wound dressing postoperative application, which contains two adhesive areas of different degrees of coupling around the absorbent pads. At the same time as absorbent pads can be used fibrous nonwoven materials. Adhesive region different adhesion forces provide the possibility of easy removal without damage to the injured skin.

In the two patent documents US 5465735 A and US 5632731 A described nepriklausomas to the wound of wound dressings that contain supporting layer and the absorbent pad. Absorbent pads are made from multilayered, with each pad and eat two different nonwoven material with different density of fibers, which side of the wound is covered with a perforated film, nepriklausomas to the wound. Through the use of nepriklausomas film prevents traumatic removal from the wound.

In international patent application WO 98/41095 A1 describes multi-layer antimicrobial wound dressing, comprising contacting a wound layer, the absorbent layer and the covering layer. At the same time as contact with the wound layer is used a polymer film with a silver coating, which contains silver with disordered atomic structure. This can additionally be provided that the other layers can also be coated with silver. Through the use of silver with a disordered atomic structure compared to silver without atomic disorder in the presence of an electrolyte may be released increased amounts of silver.

Further, in international patent application WO 01/60599 A1 describes multi-layer antimicrobial wound dressing, comprising contacting the wound covered with a layer of silver textile material, for example silver-plated fabric or non-woven material coated with gel. Thus it is essential that the silver was extracted from the wound dressing to a wound in the form of ions to combat microorganisms.

In addition, in the international patent application WO 2004/112852 A1 describes a multilayer antimicr the service of the wound dressing, which has one side covered with a silver film contact with the wound. This is covered by the silver side facing the absorbent layer. Due to this arrangement must be received antimicrobial wound dressing that provides the wound with silver sufficient to kill microorganisms without staining from abrasion silver.

Further, in patent application DE 10108083 A1 describes an absorbent smell (deodorizing) wound dressing containing silver as an antimicrobial agent. This antimicrobial agent forcibly entered or in a layer different from the odor absorbent layer, or applied thereto. Due to this, should get a wound dressing with improved neutralization of smell, and wound dressing simultaneously allocates silver and thus can destroy the microorganisms in the wound.

All described wound dressings have a common disadvantage in that when used as directed in a wound is allocated silver with a very high concentration.

The INVENTION

Accordingly, the object of the invention is to provide a wound dressing with improved absorption properties, which, even after prolonged use on the wound, with moderate to high exudate prevents infection by microorganisms, and the wound dressing does not load Podles the General treatment of the wound excessive biologically active substances. In addition, there should be created a wound dressing that prevents maceration of the wound and surrounding area of skin. According to the following aspect should be created wound dressing that long-term use reduces the risk of adhesion to the wound and simultaneously prevents maceration.

These tasks are solved in the wound dressing, with signs on paragraph 1 of the claims. According to him, the wound dressing according to the invention contains a base layer and an absorbent pad and absorbent pad includes a first absorbent layer comprising a first absorbent material and different from the first layer of the second absorbent layer containing different from the first material of the second absorbent material, the first layer is held at a distance from the second layer through at least one of the third layer and the third layer contains at least one antimicrobial agent.

In the context of the present invention under the absorbance should be understood solely absorption of liquids. Further, in the context of the invention under the hold at a distance, you should understand the spatial separation of the two components, and this spatial separation can be carried out completely or only on the plots, there are two spaced apart from each component are separated from each other on partial areas, and the other parts may be in direct contact.

Thus, you can create a wound dressing containing an antimicrobial agent, which, when using wound dressings do not come into direct contact with the wound, so that the wound does not overdose antimicrobials. In addition, a wound dressing arrangement of layers according to the invention, in which the antimicrobial agent exerts its action solely within the absorbent pads. In addition, a wound dressing that depending on the flow of exudate from the wound takes an increased amount of wound exudate, it absorbs and keeps away from the wound. Due to this existing bacteria are deprived of the nutrient medium.

According to a preferred exemplary embodiment provides that the second absorbent layer is located between the first absorbent layer and bearing layer. At the same time, or independently, may be provided that the first absorbent layer is made in a layer of the liquid distribution and the second absorbent layer is made in a layer of accumulation or storage of the liquid. However, both absorbent layers have absorption properties. In particular, the wound dressing according to the invention includes first and second absorbent layers, which in the use of the implement of wound dressings for the appointment do not contain antibacterial agents.

According to the invention as absorbent materials can be used in a variety of known materials for wound care. Especially preferred turned out to be as absorbent materials for the first and/or second absorbent layers are fibrous materials. In particular, the invention provides that both the first and the second absorbent layer is made from fibrous materials. Especially preferred showed himself to be a solution in which the absorbent pad includes a first absorbent layer and a second absorbent layer, and the second absorbent layer has a higher free absorption than the first absorbent layer, free absorption is determined in accordance with DIN EN 13726-1 (2002).

At the same time, or independently, preferably the first absorbent layer in a state of use of wound dressings for the purpose of facing the wound, while preferably the first absorbent layer is a wound in direct or indirect contact. Thus, when using wound dressings on purpose Raney exudate is kept away from the wound, and the first absorbent layer transports Raney exudate in one direction to the second layer and the second absorbent layer building up the supports and stores Raney exudate. This can be also created wound dressing that is particularly well absorbs Raney exudate, the wound is maintained essentially in a dry condition and prevents its maceration. Due to transportation of wound exudate in one direction it is placed in direct contact with the antimicrobial agent of the third layer, which exerts its antimicrobial effects. Thus, the wound dressing can remain on the wound for a longer time without reverse contamination of the wound by microorganisms from the wound dressing.

In particular, however, the first absorbent layer has an absorbance (A1the size of at least 0.5 g/g, preferably at least 2 g/g and particularly preferably at least 4 g/g, free absorption of A1determined in accordance with DIN EN 13726-1 (2002). Thus preferably provided that the first absorbent layer has an absorbance (A1value not more than 10 g/, Thus, particularly preferably the first absorbent layer has an absorbance (A1the value of at least 1 g/g to 10 g/g, even more preferably at least 2 g/g to 10 g/g and particularly preferably at least 5 g/g to 10 g/year

Further, simultaneously or independently of what it is preferably provided, the second absorbent layer has an absorbance (A2the size of at least 12 g/g, preferably at least 15 g/g and particularly preferably at least 20 g/g, free absorption of A1determined in accordance with DIN EN 13726-1 (2002). Thus preferably provided that the second absorbent layer has an absorbance (A2value not more than 50 g/, Thus, particularly preferably the second absorbent layer has an absorbance (A2the size of at least 12 g/g to 50 g/g, even more preferably at least 15 g/g to 50 g/g and particularly preferably at least 20 g/g to 50 g/year

At the same time, or independently, the wound dressing includes an absorbent pad which is free absorption of ATthe size of at least 8 g/g, preferably at least 12 g/g and particularly preferably at least 20 g/g, free absorption of A1determined in accordance with DIN EN 13726-1 (2002). This preferably provides that the absorbent pad has a free absorption of ATvalue not more than 50 g/, Thus, particularly preferred absorbent pad has a free absorption of ATthe size of at least 8 g/g up to 50 g/g, even more preferably, ENISA least from 12 g/g to 50 g/g and particularly preferably at least 20 g/g to 50 g/year

Further, simultaneously or independently, wound dressing according to the invention contains a first absorbent layer and different from the first absorbent layer of the second absorbent layer, with their free absorption (A1and A2selected so that the relation A1:A2corresponds to a ratio of from 1:2 to 1:10. Particularly preferably, the ratio A1:A2corresponds to a ratio of from 1:3 to 1:10 and particularly preferably from 1:5 to 1:10.

According to the following exemplary embodiment of the invention provides that the first absorbent material contains cellulose or viscose fibers. Thus, in particular, provided that the first absorbent material contains a fibrous non-woven material, which contains viscose fibers and thermoplastic fibers, preferably consists of, and as thermoplastic fibers can preferably be used polypropylene or polyethylene fibers. These thermoplastic fibers can also be a so-called two-component fibers fiber type core-shell".

In particular it is also envisaged that the second absorbent material contains fibers with ultra-high absorptive capacity. Etiology have particularly high free absorption and unlike consisting of particles of materials of ultra-high absorption capacity has the advantage of which is especially good mixed with other fibers and can be fixed. Thus, when using superfine fibers absorption is not required to enter into a second absorbent layer in the shell.

In particular, however, the second absorbent layer comprises a material absorbent fibrous non-woven material, which contains a fibrous mixture of fibers of ultra-high absorption capacity and the underlying fibers. However, it can also be provided that the fibrous nonwoven material contains fibers of ultra-high absorption ability and the base fiber and the base fibers selected from the group of thermoplastic fibers and/or cellulose fibers, and/or viscose fibers. Particularly preferably fibrous mixture contains fiber ultra-high absorption capacity, viscose fibers and thermoplastic fibers, and thermoplastic fibers can preferably be used polypropylene or polyethylene fibers. These thermoplastic fibers can also be a so-called two-component fibers fiber type core-shell".

Thus preferably the second absorbent material contains a fibrous mixture, which contains more than 20 wt.%, even more preferred is sustained fashion for more than 30 wt.%, even more preferably more than 40 wt.%, even more preferably more than 50 wt.% and particularly preferably more than 60 wt.% fibers of ultra-high absorption capacity. Due to that, there can be an absorbent pad, which has a particularly high free absorption. Appropriate wound dressing can remain on the wound for up to three days or longer.

The definition of "ultra-high absorption capacity" refers to capable of swelling in water insoluble material in the form of fibers, which are capable of absorbing water in an amount of at least about 10-fold, preferably at least about 20-fold, and particularly preferably at least 50 times its own weight of fibers and more. When this material is ultra high absorption capacity can be formed of organic material, which may contain synthetic and/or natural material, such as agar-agar, pectin and guar gum, or synthetic materials such as synthetic polymer hydrogels. Synthetic polymer hydrogels include, for example, carboxymethylcellulose, alkali metal salts of polyacrylic acid, alkali metal salts of polymethacrylic acid, polyacrylamide, polyvinyl alcohol, copolymers of ethylene with maleic acid anhydride, watering Silovye ethers, hydroxypropylcellulose, polymers and copolymers of vinyl sulfonic acid, polyacrylates, polymethacrylates, copolymers of polyacrylate with polymethacrylates, polyacrylamides and the like polymers. As the fibers of ultra-high absorption ability is particularly preferred fibers obtained from alkali metal salts of polyacrylic acid, alkali metal salts of polymethacrylic acids, polyacrylates, polymethacrylates or copolymers of polyacrylate with polymethacrylates. Polymer hydrogels preferably have a small amount of cross-linking to give these materials a substantial insolubility in water. The crosslinking can be carried out, for example, by irradiation or by covalent, ionic Vander Waals (intermolecular) or hydrogen bridge connection. Suitable materials can be obtained from various manufacturers, such as BASF and Stockhausen Inc.

Further, preferably provided that the second absorbent layer comprises a material absorbent fibrous non-woven material, which is composed of fibrous mixtures containing at least 20 wt.% fibers of ultra-high absorption capacity of at least 10 wt.% viscose or cellulose fibers and at least 5 wt.% thermoplastic fibers. Especially preferably provided is but the second absorbent layer comprises a material absorbent fibrous non-woven material, which consists of a fibrous mixture containing at least 40 wt.% fibers of ultra-high absorption capacity of at least 20 wt.% viscose or cellulose fibers and at least 5 wt.% thermoplastic fibers. At the expense of the share of basic fibers in the fibrous non-woven material at the beginning of the absorption is uniform distribution subject to absorption of fluid.

In a particularly preferred examples of the execution of the wound dressing includes an absorbent pad with a thickness of the S layer is from 0.1 to 10.0 mm, In particular wound dressing according to the invention contains an absorbent pad with a thickness of the S layer is from 0.1 to 8.0 mm, preferably from 0.1 to 7.0 mm, and particularly preferably from 0.5 to 5.0 mm Wound dressings with such a layer thickness showed, on the one hand, their ability a long time away from the wound Raney exudate, and good ability to fit. This thickness of the layer may be the same in any place absorbent pads or may be different in different areas of the pads.

According to the invention the first and second absorbent layers should be kept at a distance from each other through the third layer and the third layer contains ant the microbial agent. Thus, the third layer provides antimicrobial agent that exerts its influence within the wound dressing and kills the microorganisms inside it. This turned out to be preferred, when the third layer is used over a thin layer compared to the first or second absorbent layers.

In the decision on development of the inventive ideas of the wound dressing preferably contains as a third layer of polymer mesh, perforated plastic film, a fibrous non-woven material or a textile material, such as knitted fabric, knitted fabric or cloth. This may preferably be provided that the third layer consists of a polymer mesh or perforated polymer film, which has a lot of holes, openings or slits, or channels with an average diameter of from 0.01 to 1 mm, preferably from 0.1 to 1 mm, for passage of fluids, especially wound exudate.

Further, preferably, the third layer can contain many holes, holes, slots, or channels, and these holes, holes, slots, or channels occupy an area equal to at least 20% of the area of the third layer. Especially preferably, holes, holes, slots, or channels occupy an area equal to at least 25%, even more preferably at least 30% and especially predpochtitelno, at least 35% of the area of the third layer.

Particularly preferably in contact with the wound layer contains holes, holes, slots, or channels, which occupy at least 20% and not more than 80% of the area of the third layer. Particularly preferably, the wound dressing contains contact with the wound layer, which has from 10 to 100 holes on 1 cm2. It may be provided that are in contact with the wound layer is a perforated polymer film or a polymer network, in particular polyethylene or polypropylene. Thus, the first absorbing layer and second absorbing layer can defend from each other at a sufficient distance and at the same time can be a sufficient amount of antimicrobial agent.

It may be provided that the antimicrobial agent directly deposited on the third layer. But it can also be provided that the third layer impregnated with antimicrobial agent or it is included in the third layer.

Especially preferred in the following example, run as a third layer is used polymeric mesh or perforated polymer film, non-woven or textile material, such as knitted fabric, knitted fabric or cloth which is coated or impregnated with silver. But it can also be provided, the silver included in the third layer. At the same time or independently can be, in particular, provided that silver is used in the form of elemental silver, silver oxide, silver or silver salt, or mixtures thereof. Thus, the wound dressing according to the invention contains as an antimicrobial agent in elemental silver, silver oxide, silver in the form of complexes of silver or silver salts. It is particularly preferred use of elemental silver as an antimicrobial agent. In its elementary form, the silver has a very low ionic product and due to this, compared with other antimicrobial substances in the presence of wound exudate secretes very low concentrations of a substance. However, this concentration is sufficient to provide antimicrobial effect within the wound dressing. Not to go into theory, within the wound dressing according to the invention, the silver is chemically bound in the elementary form on the third layer, exerts its effects in the form of ions or complexes of silver released from elementary compounds by wound exudate. However, these ions tend to interact with oppositely charged ions. In the case of positively charged silver ions and the use of fibers of ultra-high absorption capacity of the Olga polyacrylic acids or polyacrylates, which, as you know, have negatively charged region, these unleashed by wound exudate ions or complexes of silver held by the fibers within the wound dressing. While silver is at a very low concentration can act only within the wound dressing, resulting in preventing contamination of the wound is too large quantities of silver.

According to further aspect of the inventive idea, an absorbent pad releases silver in elemental form or in the form of salts or complexes of silver in the amount of less than 25 micrograms of silver per 1 g of absorbent pads for 24 hours at 25°C in 100 ml of water or of physiological saline, preferably less than 15 μg of silver per 1 g of absorbent pads for 24 hours at 25°C in 100 ml of water or physiological salt solution, and particularly preferably less than 5 mg of silver per 1 g of absorbent pads for 24 hours at 25°C in 100 ml of water or physiological salt solution. To determine the allocated amount of silver used atomic absorption spectroscopy.

According to the following example of the invention, the wound dressing may contain at least one or more other layers that perform different functions in the overall system of wound dressings. In particular can be envisaged is Moreno, that the absorbent pad further comprises contacting the wound layer, which preferably is in direct contact with the first or with the second layer. Particularly preferably, however, this contact with the wound layer when using wound dressings for the appointment does not contain antimicrobials. Thus, you can create a wound dressing containing an antimicrobial agent, which acts only within the wound dressing.

According to another example embodiment of the invention can also be provided that the wound dressing contains contact with the wound layer, which has the same area fit that and a supporting layer. It may be provided that are in contact with the wound layer in the area of absorbent pads is in direct contact with the first or with the second layer, and in the area of the edges of the wound dressing is connected with the carrier layer. In this example implementation in contact with the wound layer together with the supporting layer to form a wrapper for absorbent pads.

It is particularly preferred embodiment, when in contact with the wound layer is a polymer mesh or a perforated plastic film. These polymeric mesh or perforated films have the advantage that the n is bonded to the wound. Thus, through the use of such films or meshes can be created wound dressing does not stick to the wound.

Thus, in particular, can also be provided that the contact with the wound layer consists of a polymer mesh or a perforated film, which contains many holes, holes, slots, or channels with an average diameter of from 0.01 to 1 mm, preferably from 0.1 to 1 mm, for passage of fluids, especially wound exudate.

Further, preferably in contact with the wound layer can contain many holes, holes, slots, or channels, and these holes, holes, slots, or channels occupy an area of not more than 30% of the surface area in contact with the wound layer. Especially preferably, holes, holes, slots, or channels occupy no more than 25%, even more preferably not more than 15% and especially preferably not more than 10% of the surface area in contact with the wound layer. Particularly preferably, holes, holes, slots, or channels occupy an area at least equal to 10% and not more than 20% of the area of the first side in contact with the wound layer. Particularly preferably, the wound dressing contains contact with the wound layer, which has from 10 to 100 holes on 1 cm2. It may be provided that are in contact with the wound layer is a polymer mesh is whether perforated polymer film, in particular, of polyethylene or polypropylene.

According to another preferred example of the invention, the wound dressing comprises a contact wound layer of polymer mesh or perforated plastic film of polyethylene or polypropylene and the first absorbent layer from the first absorbent material that contains a fibrous non-woven material. When this fibrous nonwoven material contains from 80 to 99 wt.% viscose fibers and 1 to 20 wt.% thermoplastic fibers and thermoplastic fibers are preferably of polypropylene or polyethylene fibres in the form of a so-called two-component fibers of type "core-shell". Particularly preferably in this embodiment, the fibrous non-woven material contains 85 wt.% viscose fibres and 15 wt.% component fibers of type "core-shell". The share of the component fibers in the fibrous non-woven material may enhance the adhesion between the first absorbent layer and in contact with the wound layer.

According to the invention as a base layer may be used any known modern bearing material that has sufficient tensile strength and essentially impermeable to liquids. At the same time as the base layer in the wound dressing according to the invention m is gut, in particular, be used fibrous non-woven material or a polymeric film. In addition, it is preferable for the base layer of the wound dressing in accordance with the present invention to use, in particular, waterproof polymer films which have high permeability to water vapor. Particularly suitable for this film, made from polyurethane, simple polyetherurethane, complex polyetherurethane, copolymers of polyester with polyamide. In particular, for the base layer is particularly preferred waterproof and permeable to water vapor polyurethane film, a film of the complex polyetherurethane or simply polyetherurethane. Particularly preferred film having a thickness of from 15 to 50 μm, even more preferably from 20 to 40 μm, and particularly preferably from 25 to 30 μm. The permeability of the polymer film to water vapor is preferably at least 750 g/m2/24 h, even more preferably at least 1000 g/m2/24 h and especially preferably at least 2000 g/m2/24 h (measured in accordance with DIN EN 13726-2). In a particularly preferred examples of the execution of these films have a water resistant adhesive edge area. This edge area provides the ability to overlay and fixation of wound dressings on the destination. CCA is i.i.d. preferred while adhesives, which when applied in a thin layer with a flow rate of from 20 to 35 g/m2have together with the film permeability to water vapor of at least 800 g/m2/24 h, even more preferably at least 1000 g/m2/24 h (measured in accordance with DIN EN 13726-2 (2002)).

However, according to the following embodiment may also be used as the base layer of the wound dressing fibrous nonwoven materials. In particular, these fibrous nonwoven materials can be made of hydrophobic fibers and sealed with a water jet.

You can also use as a base layer fibrous nonwoven materials produced by spunbond-inflatable technology "meltblown", fibrous nonwoven materials "Spunlace" or non-woven materials, the resulting technology air laying, preferably these fibrous non-woven materials made of polyurethane block copolymers polystyrene-isoprene block copolymers polystyrene-butadiene, complex, polyester, polyolefin or complex poliefirimidov.

A BRIEF DESCRIPTION of GRAPHIC MATERIALS

Hereinafter the invention will be described in a non-restrictive examples of execution with reference to the drawings. In the drawings:

in Fig.1 shows the top view of the wound dressing in accordance with, and the acquisition,

in Fig.2 and 3 shown in the cross section of the wound dressing in alternative examples of implementation.

INFORMATION CONFIRMING the POSSIBILITY of carrying out the INVENTION

In Fig.1 in the top view is shown of the wound dressing 10 in the first exemplary embodiment. Wound dressing contains supporting layer 11 and the absorbent pad 15. Supporting layer 11 on its rear side is covered over the entire area of skin friendly contact adhesive (not shown). The absorbent pad 15 is located in the centre of the base layer, so that it completely surrounds the adhesive edge for attachment to the patient's skin. The wound dressing 10 is made in the form of so-called " island of the overlay.

In Fig.2 wound dressing 20 according to the invention is shown in cross section. Wound dressing contains supporting layer 21 made of waterproof fibrous non-woven material over the entire area covered acrylate contact adhesive 22. Through the contact of the adhesive 22 in the center of the base layer 21 reinforced absorbent pad 25, so for attachment to the patient's skin remains unclosed adhesive region surrounding the absorbent pad on all sides. Absorbent pad 25 made of multilayer and comprises a first absorbent layer 28 of the first absorbent fibrous material of the second absorbent layer 24 of the second absorbers the th material (hydrophilic polyurethane foam) and located between the first and second layers, the third layer 26, which separates from one another the first and second layers. The third layer 26 consists of a mesh of plastic film, which with both sides coated with elemental silver. The polymeric film is coated so that the holes of the mesh film remain open for the passage of wound exudate, so the possible flow of exudate from the first absorbent layer to the second. The first absorbent layer 28 has a lower free absorption than the second absorbent layer 24. Thus, the use of wound dressings on purpose Raney exudate may be taken the first absorbent layer, and then to accumulate in the second absorbent layer. Thanks Raney exudate essentially removed from the wound and prevents its maceration. Due to the location covered with silver polymer film between two absorbent layers of the wound dressing even when a prolonged stay on the wound for three to five days is supported free from microorganisms, so that reverse suppressed infection of wounds by microorganisms. Ready wound dressings for use facing toward the body of the patient side before using closed removable paper 23.

In Fig.3 shows a cross-section of the wound dressing 30 according to the invention the following example is run. R is Neva bandage consists of a base layer 31 of hydrophobic fibrous nonwoven material, that entire area is covered acrylate contact adhesive 32. A laminate consisting of a contact adhesive 32 and the base layer 31, permeable to water vapor, which ensures the creation of a "breathable" or gas-permeable wound dressing. Centrally symmetrically on the support layer 31 reinforced multi-layer absorbent pad 35, with adhesive left edge 39 for fastening on the body. Absorbent pad 35 is composed of the first absorbent layer 38 of the first absorbent fibrous material of the second absorbent layer 34 of the second absorbent material, different from the first, and located between the first and second layers, the third layer 36, which separates from one another the first and second layers. The third layer 36 consists of a mesh of plastic film, which with both sides coated with elemental silver. The first absorbent layer 38 contains as an absorbent material designed needles fiber cloth made of viscose fibres. The second absorbent layer 34 contains as an absorbent fibrous material with a mixture of ultra-high absorption capacity polyacrylate fibers and viscose fibers. Due to the content polyacrylate fibers of ultra-high absorption capacity of the second absorbent layer 34 has a significantly higher absorption than the first and the absorptive layer 38. In addition, the absorbent pad contains permeable to wound exudate nepriklauisomybe to the wound in contact with the wound layer 37 of the polymer film or polyethylene. Thanks to the chosen system of layers Raney exudate away from the wound and prevents maceration of the wound and the adjacent edges. Due to the location covered with silver polymer film between two absorbent layers of the wound dressing even when a prolonged stay on the wound for three to five days is supported free from microorganisms, so that reverse suppressed infection of wounds by microorganisms. Ready wound dressings for use facing toward the body of the patient side before using closed removable paper 33.

DESCRIPTION of exemplary embodiment of INVENTION

I) test Methods

1) Free absorption of saline solution Test 1

Free absorption of physiological sodium chloride solution (0.9 wt.% NaCl in water) is determined in accordance with EN 13726-1 (2002). The only difference from DIN EN 13726-1 (2002) is the use of NaCl instead of NaCl and CaCl2if this is true the following equation:

where

M2= wet weight of sample, g

M1= dry weight of sample, g

2) the Release of silver Test 2

On what I determine the release of silver from wound dressings sample absorbent pads (without the base layer) of size 5×5 cm was immersed in filled with distilled water, close the flask Erlenmeyer, so that the absorbent pad was completely covered with water. The sample was left in a closed flask for 24 hours at 25°C. After 24 hours the sample was removed from the flask, filtered, the remaining liquid was determined by the silver content in the filtered liquid by atomic absorption spectroscopy.

II) Design of wound dressings

The wound dressing has essentially the structure according to Fig.3, with further description of individual components of wound dressings used the same concepts or terms. Wound dressing consists of a suspension of waterproof material, a strong water jets fibrous canvas of complex fibers of polyester with a weight per unit area of 70 g/m2(Sontara 8010, Du Pont). On the carrier material covers the entire area of the applied hot-melt adhesive based on synthetic rubber in the amount of 35 g/m2. The wound dressing has a size of 8×10 cm, and an absorbent pad (type P 2007/123/7/3; firm Kemex - Al Almelo, the Netherlands) dimensions 6×4 cm mounted on the glue centrally symmetrically, so that the absorbent pad surrounded by gluing the edge width of 2 cm Each layer of absorbent pads on its outer perimeter has the same dimensions as the second layer of absorbent pads.

The absorbent pad contains nepriklauisomybe to the wound contact the rd with the wound layer, on which lamination is deposited first absorbent layer of the worked needles fiber canvas, consisting of a fibrous mixture of viscose rayon fibers, polyethylene fibers and polypropylene fibers with a weight per unit area of 32 g/m2. In contact with the wound layer has a number of holes or slots for the passage of liquids, and these holes or slits occupy about 20% of the area of the wound contact layer.

Fibrous non-woven material of the first absorbent layer has a weight per unit area of 275 g/m2and free absorption 1965 g/m2(measured in accordance with DIN EN 13726-1 (2002) - test 1). Thus, the free absorption of A1the first absorbent layer is A1=7,1 g/g

In addition, the absorbent pad comprises a second absorbent layer of a fibrous non-woven material obtained according to the technology of air laying (Air-Laid). Fibrous material air styling consists of a fibrous mixture containing 20 wt.% (with respect to the mass of material air-laying) with ultra-high absorption capacity polyacrylate fibers of a copolymer of polyacrylate-polymethylacrylate, 75 wt.% viscose fibers and 5 wt.% thermoplastic bicomponent fibers of polyethylene and polypropylene. Fibrous non-woven material without what's styling has a weight per unit area of 85 g/m 2and free the absorbance 1800 g/m2(measured in accordance with DIN EN 13726-1 (2002) - test 1). Thus, the free absorption of A2the second absorbent layer is A2=21,2 g/, While (A1to A2is 1:3.

Between the first and second absorbent layers is a polymer mesh made of polyethylene, coated with silver on one side, with a silver layer facing to the first absorbent layer. Polymer mesh coating has a weight per unit area of 20 g/m2and the quantity of elemental silver in a polymer mesh is from 150 to 300 mg/m2. Polymer network contains a number of holes or slots for the passage of liquids, and these holes or slits occupy an area equal to approximately 50% of the area of polymer mesh. The total mass of absorbent pads is 412 g/m2moreover , the absorbent pad has a free absorption 3765 g/m2(measured in accordance with DIN EN 13726-1 (2002) - test 1). Thus, the free absorption of ATabsorbent pads is AT=9,1 g/year

Wound dressing should not be called antimicrobial, as the rate of release of silver in the wound dressing is just to 11.3 mg of silver per 1 g of absorbent pads for 24 hours at 25°C in 100 ml of water with release of silver in elemental form is whether in the form of salts or complexes, to determine the allocated amount of silver used atomic absorption spectroscopy. Thus, the antimicrobial agent operates almost exclusively within the wound dressing. Due to this, when using this wound dressings for the appointment does not create an excess of added substances on the surface or inside of the wound.

1. Wound dressing (20, 30) for the treatment of wounds from medium to high exudate containing base layer (21, 31) and an absorbent pad (25, 35), and an absorbent pad (25, 35) includes a first absorbent layer (28, 38), containing the first absorbent material and different from the first layer of the second absorbent layer (24, 34), containing different from the first material of the second absorbent material, the first layer (28, 38) is held at a distance from the second layer (24, 34) by at least one third layer (26, 36), and this third layer (26, 36) contains at least one antimicrobial agent, wherein the second absorbent material contains fibers with ultra-high absorption capacity and absorbent pad (35) further comprises contacting the wound layer (37), which is in direct contact with the first layer (38), and in contact with the wound layer (37) is a polymer mesh libertarian polymer film, this antimicrobial agent is an elemental silver, silver oxide, a complex of silver or silver salt, or mixtures thereof, and having ultra-high absorption capacity of the fiber obtained from the salts of polyacrylic acids or polyacrylates.

2. Wound dressing (20, 30) p. 1, wherein the first absorbent layer (28, 38) in the use of wound dressings for the purpose of facing the wound, and is wound in indirect contact.

3. Wound dressing (20, 30) p. 1, wherein the first absorbent material and the second absorbent material is a fibrous material.

4. Wound dressing (20, 30) p. 1, characterized in that the second absorbent layer (24, 34) has a higher free absorption than the first absorbent layer (28, 38).

5. Wound dressing (20, 30) p. 1, characterized in that the ratio of free absorption of A1the first absorbent layer to the free absorption of A2the second absorbent layer is selected so that the relation A1:A2corresponds to a ratio of from 1:2 to 1:10.

6. Wound dressing (20, 30) p. 1, characterized in that the third layer (26, 36) is a polymer mesh or perforated plastic film, coated with antimicrobial agent.

7. Wound dressing (20, 30) p. 1, characterized in that the contact with the Russian Academy of Sciences the first layer (37) and/or the first absorbent layer (28, 38) contains no antimicrobial agent.

8. Wound dressing (20, 30) p. 1, characterized in that the carrier layer (21, 31) is composed of fibrous non-woven fabric or plastics film.



 

Same patents:

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to surgery, and can be used in treating plantar warts. That is ensured by administering nicotinic acid and Trental in a therapeutic dose 2 weeks before exposure. Then, a keratous portion of the plantar wart is enucleated surgically in an even layer 2 mm thick to derma and anaesthetised with 10% lidocaine. That is followed by cryotherapy at a temperature of -170°C by three cycles of freezing and thawing of the tissue at 1.5 diameters of the pathological tissue and covering the intact tissue within one procedure. The cryotherapy covering the pathological centre is followed by applying Allomedin gel 1 g per 1 cm of the wart diameter. Thereafter, Gehwol orthopaedic ring plaster is applied so that the papilloma is in the middle of its opening. That is covered with an adhesive plaster to be removed 24 hours later. The wound is washed in flowing water, iodinated to form a dry scab. Gehwol ring plaster is applied for 3 weeks.

EFFECT: method provides the stable positive therapeutic sparing effect on the pathological centre and the prevented excessive tissue injuries by an optimum combination and mode of use of pharmaceutical preparations, plaster and cryotherapy.

1 ex

FIELD: packaging industry.

SUBSTANCE: according to the invention, the package for self-adhesive adhesive tape accommodates an adhesive tape 14 having a substrate 20 and an adhesive agent layer 12 on one surface of the substrate, and the adhesive tape 14 is bent to form a first area 22 and a second area 24 so that an adhesive agent layer faces outwardly. Furthermore, the package 10 for the self-adhesive adhesive tape comprises a first removable sheet 16 attached with the ability of detachment to the layer of the adhesive agent of the first area of the adhesive tape, and a second removable sheet 18 attached with the ability of detachment to the layer of the adhesive agent of the second area of the adhesive tape for sealing together with the first removable sheet between the first and second movable sheets. With such a configuration it is possible to eliminate the conventionally frequent package. Furthermore, when the second removable sheet is removed from an adhesive agent layer of the second area of the adhesive tape, the half of the adhesive agent layer is opened; respectively, the application on the area for the application is simplified.

EFFECT: package for self-adhesive adhesive tape is proposed, in which despite the fact that simplicity of application of the adhesive tape is achieved, the effect of maintaining the resource can be obtained.

19 cl, 13 dwg, 1 tbl

Wound dressing i // 2528894

FIELD: medicine.

SUBSTANCE: invention refers to medicine, and represents a wound dressing containing a substrate and an elastomer matrix forming a wound-facing layer and having waterproofed polymer biguanide as an active substance homogenously distributed in the elastomer matrix. What is also described is a material representing the elastomer matrix with the homogenously distributed waterproofed polymer biguanide for preparing the wound-facing layer for the wound dressing.

EFFECT: antimicrobial activity of waterproofed polymer biguanide and effect is ensured by the uniform distribution thereof in the elastomer matrix, as well as by controlled release.

14 cl, 5 ex, 2 tbl

FIELD: medicine.

SUBSTANCE: invention refers to medicine. What is described is an adhesive plaster, wherein each of the elements of a carrier, a protective film and an adhesive layer has a flat rectangular shape, while a projecting portion is formed on a surface from the carrier of the adhesive plaster angularly. Besides, the adhesive plaster can be formed to have a middle portion and a periphery, while the projecting portion can be formed angularly after the rectangular middle portion. Besides, between adjoining, at least two projecting portions there can be presented a connective component element wherein the thickness of the adhesive plaster is lesser than that of the adhesive plaster in the projecting portion.

EFFECT: plaster prevents bisoprolol or its salt leakage from the adhesive layer thereby avoiding impoverishment of the therapeutic agent.

6 cl, 6 dwg, 4 tbl, 8 ex

FIELD: medicine.

SUBSTANCE: invention relates to a haemostatic anti-burn and wound-healing composition in the form of a hydrogel, which contains an active gel-forming component, a plasticiser, active and auxiliary components, namely a water-soluble heteropolymer of chitosonium salt in an amount from 1.0 to 10.0 wt %, a dexpanthenol substance and/or a 2-allyloxyethanol substance in an amount from 1.0 to 10.0 wt %, immobilised medicinal substances of aminocaproic or tranexamic acid in an amount from 0.1 to 5.0 wt % and calcium chloride in an amount from 0.05 to 2.0 wt %, immobilised medicinal substances of lidocaine or anylocaine in an amount from 0.1 to 5.0 wt % and chlorhexidine in an amount from 0.005 to 0.1 wt % and water.

EFFECT: extension of exploitation possibilities in stopping external capillary bleedings, local treatment of injured skin, non-healing wounds and local burns.

10 cl

FIELD: packaging industry.

SUBSTANCE: invention relates to a package in which the adhesive tape is packaged, which has a layer of adhesive agent on the substrate. The package 10 for the self-adhesive adhesive tape comprises the adhesive tape 14 having a substrate 18 and the adhesive agent layer 12, provided on one surface of the substrate 18, and comprises a release sheet 16 is attached with the ability to release to the adhesive agent layer 12. The release sheet 16 is folded along a predetermined fold line with the adhesive tape 14 so that the adhesive agent layer faces outwardly and the folded adhesive tape 14 is sealed inside the folded release sheet 16.

EFFECT: according to this configuration, the traditionally occurring package separate from the release sheet can be eliminated; moreover, when the release sheet 16 is opened as detaching of the release sheet 16 from the adhesive agent layer 12 of the adhesive tape 14, half of the adhesive agent layer 12 is opened making the process of applying to the area for applying simple.

18 cl, 15 dwg

Wound bandage // 2519683

FIELD: medicine.

SUBSTANCE: invention relates to medicine, in particular to a multi-layered wound bandage for treatment of wounds in granulation and epithelisation phases. Described is the wound bandage, which contains a) the first layer as a layer of contact with the wound, which has the first side and the second side, and b) at least, one second layer as an absorbing layer with the first side and the second side, containing hydrophilic polyurethane foam, with polyurethane foam having a water content equal to, at least, 10 wt %.

EFFECT: wound bandage transmits low displacing effort to the processed wound.

7 cl, 3 dwg, 1 ex

FIELD: medicine.

SUBSTANCE: invention refers to medicine. What is described is using active ingredients as exemplified by GML (Glycerol Monolaurate) on a fibrous absorbent structure, such as viscose fibre, used for tampons production, in the very low concentrations enables maintaining effectiveness on the inhibition of synthesis of a toxic shock syndrome toxin 1 (TSST-1) produced by S.aureus, without evident microorganism elimination for the purpose of achieving the desired reduction of the toxin concentration and avoiding undesired impurities.

EFFECT: achieving the desired reduction of the toxin concentration and avoiding undesired impurities.

16 cl, 6 tbl, 3 ex

FIELD: medicine.

SUBSTANCE: invention refers to medical equipment, namely to a drainage system, particularly for aspiration in case of the aspiration treatment of fistulas, surgical wound dehiscences, decubitis ulcers, injuries and other similar damages, such as venous and arterial ulcers or diabetic foot related injuries. The drainage system comprises an aspiration bag carried by a sheet member that can be coupled with a cavitary injury and that is coupled or can be coupled with an aspirator by means of a joint member, and also at least one drainage layer inside the above drainage bag. The above sheet member is used as a carrier for the joint member.

EFFECT: invention makes the treatment and rehabilitation period more comfortable for the patient by ensuring a greater ease of locomotion when draining the fluids with no risk of a direct effect of the joint member on the treated skin causing discomfort, pains and a risk of making the involved skin worse.

13 cl, 17 dwg

FIELD: medicine.

SUBSTANCE: there are described the improved skin adhesive compositions for the attachment of a substrate, such as an absorbent product to the skin. The skin adhesive composition can provide one or more skin effective agents. The skin adhesive composition can be applied on an absorbent product, such as a liner, a hygienic napkin or a product used for incontinence for the direct adhesion of the given product to the user's skin.

EFFECT: skin adhesive composition is characterised by the improved, yet soft adhesion to the user's skin with maintaining the strong and effective attachment to various non-living substrates, other than skin.

14 cl, 3 tbl, 6 dwg, 3 ex

Absorbing product // 2532727

FIELD: personal use articles.

SUBSTANCE: disposable diaper contains a back and a front parts, an absorbing element, a belt flap and a hydrophilous sheets set. The hydrophilous sheets set includes an inner hydrophilous sheet and an outer hydrophilous sheet; the inner hydrophilous sheet and the outer hydrophilous sheet are in the belt zone containing a zone overlapping the belt flap edge and the absorbing element end. The belt flap having an outer hydrophilous sheet and an inner hydrophilous sheet additionally contains a belt elastic element fixed in the flap in a condition wherein the belt elastic element is stretched in a cross direction of the disposable diaper so that the flap forms frills. The outer hydrophilous sheet has higher liquid absorbing capacity than the inner hydrophilous sheet and contains two outer hydrophilous sheets where the belt elastic elements are positioned between the said two outer hydrophilous sheets; the outer hydrophilous sheet passes from the belt flap edge beyond the absorbing element end and ends over the absorbing element.

EFFECT: sweat absorbing capacity enhancement thus preventing appearance of eczema, sweat fever, contact dermatitis etc.

7 cl, 13 dwg

FIELD: medicine.

SUBSTANCE: invention refers to an orthopaedic product and an orthopaedic pad, particularly an amputation stump pad, a contact pad, a prosthesis cover, an orthesis cover, a prosthesis collar, a shoe sole or orthopaedic socks, i.e. polymer materials used in direct skin contact. The polymer material is applicable for direct skin contact and contains a fine-distributed silver as an antibacterial agent and is additionally provided with fine-dispersed particles of other metal. The metals of the group containing aluminium or aluminium alloy, magnesium, bronze, titanium and/or platinum are applicable.

EFFECT: invention enables concealing the discoloration when using the orthopaedic pad on the skin, and hence when using the orthopaedic product provided with this pad, also including for masking the discoloration in the pigmented or coloured polymer materials applicable in air or skin contact.

7 cl, 1 tbl

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention relates to the field of pharmaceutics, namely represents a thixotropic preparation of a smearing consistence, which assists in healing wounds and improves characteristics of a postepithelially formed tissue.

EFFECT: invention describes a method of considerable increase of solubility of useful active substances in siloxane-matrix-forming preparations.

20 cl, 1 dwg, 4 ex, 9 tbl

FIELD: transport.

SUBSTANCE: present invention relates to conveyor and method for producing absorbing article which uses such conveyor to selectively convey continuous canvas of different sizes. Conveyor selectively conveying continuous canvas having the first article size or continuous canvas having the second article size other than the first article size includes guiding mechanism made with possibility to change position of passing at least one of the first and the second side edge portions of canvas by means of contact interaction with at least side edge portion of canvas. There are two mechanisms: detection mechanism configured to detect position of canvas side edge portion passing and driving mechanism actuating guiding mechanism and mechanism of detection of equal distance in transversal direction being perpendicular to conveying direction of canvas of the first or the second canvas size. Detection mechanism and guiding mechanism are installed to be capable of simultaneous movement, detection mechanism is electrically connected with power drive which is part of guiding mechanism and detects passing of edge portion of canvas, and guiding mechanism corrects position of roller assembly which is part of guiding mechanism by means of power drive based on detection mechanism data.

EFFECT: invention is aimed to provide conveyor and method to produce absorbing article which are capable of selective conveying any of canvases for two or more sizes by simply changing position of side edge canvas portion passing without complex control.

10 cl, 8 dwg

FIELD: machine building.

SUBSTANCE: method to produce a disposable absorbing product with a variety of components is proposed and involves selection of the first material, suitable to be used as an external coating, manufacturing of a basic element including the external coating with the latter comprising the central zone of the external coating having the appearance of the external coating central zone, selection of the second material suitable to be used as an elastic panel, the second material is different from the first material, and manufacturing of the first elastic panel having the central zone of the first elastic panel. The method also implies the application of a printed graphic image on the first elastic panel on the central zone of the first elastic panel, and attachment of the first elastic panel to the basic element, choice and application of the print are made so that the central zone of the first elastic panel provides for appearance in essence similar to the appearance of the central zone of the external coating.

EFFECT: improved design.

20 cl, 5 dwg

FIELD: medicine.

SUBSTANCE: invention relates to medicine. Described is method of treating infection of human or animal body surface, in particular, contamination with fungi, including application of water liquid on infected body surface, for instance, nail area, with further application of bandage, which includes hydrogen peroxide source. Combinations of bandage liquid for application in method are also provided.

EFFECT: combination makes it possible to considerably reduce or eliminate infection in nail area.

16 cl, 1 tbl, 2 dwg, 2 ex

Absorbent product // 2527121

FIELD: medicine.

SUBSTANCE: absorbent product comprises a liquid-permeable upper sheet (10), a liquid-impermeable or water-resistant back sheet and an absorbent element between the above sheets. The upper sheet (10) is formed of a sheet of a non-woven material having high-density segments (13a) and low-density segments (14a). Each high-density segment (13a) and each low-density segment (14a) have different densities. The high-density segments (13a) and the low-density segments (14a) are arranged in the direction of a plane of the upper sheet (10). The low-density segments (14a) have a greater amount of a skin care agent (5) applied thereon than the high-density segments (13a).

EFFECT: improving absorbent properties.

9 cl, 16 dwg

FIELD: medicine.

SUBSTANCE: device in form of napkin for cleaning, surgical processing of wounds or skin is claimed. Napkin contains at least one bearing layer (2), placed on it and projecting from it threads (3), preferably made exclusively from synthetic fibres, preferably polymer fibres. At least, some threads (3), preferably not less than 50%, on their side, opposite to bearing layer (2), have freely projecting cut ends (4), passing at angle to direction (5) of their longitudinal length. Napkin is used as complete unit with package. Invention describes two versions of method of device or napkin for wound cleaning manufacturing. In accordance with the first version of method two bearing layers are manufactured together in form of knitted fabric with formation between them of intermediate layer from threads, passing between both layers, which is cut. In accordance with the second version of method, manufactured is bearing layer with projecting from it threads, which are cut at angle to their longitudinal length.

EFFECT: increased efficiency of cleaning.

19 cl, 10 dwg

FIELD: transport.

SUBSTANCE: set of inventions relates to conveyor for canvas used in manufacturing absorbing element including absorbing substrate and shell that covers the absorbing substrate, as well as to method for manufacturing the mentioned absorbing element. Conveyor 100 moves canvas 4' of absorbing element which canvas includes absorbing substrate 4A, placed between a pair of canvases 4B and 4C to form a shell. Thickness (t1) of absorbing substrate 4A is greater than the thickness (t2) of shell. The conveyor 100 includes mechanism for changing direction, for instance direction change roller 110 which changes transportation direction of absorbing element canvas 4' by the angle of 90 degrees or more. Distance (L1) of absorbing element canvas 4' turn comprising in particular the length of direction change roller 110 semicircle is greater than the length (L2) of each absorbing substrate 4A in direction MD of absorbing element canvas 4' transportation.

EFFECT: technical result consists in more reliable suppression of manufacturing defects in absorbing elements comprising continuous canvas.

8 cl, 7 dwg, 2 ex, 1 tbl

FIELD: medicine.

SUBSTANCE: set of a hygienic absorbing product includes the hygienic product, which has a triple folded configuration before application, and an external wrapping for packing the triple folded hygienic product before application. The external wrapping has the first wall and the second wall, located opposite each other, an external surface and an internal surface, the first end part, the second end part and an intermediate part, located between the first and second end parts, an internal surface, an external surface and a protrusion, which has the first position, in which it overlaps the internal surface. The external wrapping has the first closed configuration, in which the first and second end parts of the external wrapping are located in such a way as to overlap each other, to form a packet for reception of the triple folded hygienic product before application. The external wrapping has the second open configuration, in which the first and second walls of the external wrapping form a pocket for reception of a dirty hygienic product. The protrusion has such a structure and location that a user can move it manually when the external wrapping is in the second configuration, from the first position into the second position. The protrusion is located in such a way as to overlap the external surface of the external wrapping in order to close the pocket.

EFFECT: hygiene of the sanitary napkin application is provided.

15 cl, 7 dwg

FIELD: medical engineering.

SUBSTANCE: device has foam tampon to be introduced into a wound area and material for covering the wound and sealing the foam tampon in the wound area. The foam tampon communicates to vacuum source via flowing medium to help draining the flowing medium. The foam tampon is impregnated with basic fibroblast growth factor and antimicrobial factor.

EFFECT: accelerated wound healing.

9 cl, 1 dwg

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