System containing imitative cigarette device and charging unit
FIELD: tobacco industry.
SUBSTANCE: imitative smoking device (1,51) contains an imitative cigarette having an essentially cylindrical cigarette-like shape and a charging unit (2, 50) having an essentially rectangular body shaped like a cigarette packet. The filling device (2, 50) contains charging gas (32, 59) for the imitative cigarette and a means for elective retention of the imitative cigarette. The imitative cigarette may be completely retained inside the body (3, 52). The cigarette may be retained at a place other than the charging place. A dose counter may be envisaged to give visual indication of doses in the charging device.
EFFECT: technical result achieved using the imitative cigarette device and the charging device for the imitative device according to the invention consists in smoking skill imitation, the imitative cigarette charging and its usage simplification.
7 cl, 15 dwg
The present invention relates to a system containing imitation cigarette device and the block.
According to the world health organization tobacco Smoking kills 3-4 million people per year, while the number of smokers in the world is growing every year. Nicotine replacement therapy is becoming more widespread in Western countries, but still is not so widespread influence in encouraging smokers to quit, as predicted by many. In addition, many current and former smokers are not satisfied with nicotine replacement therapy, and 67% of smokers fail to quit because they believe modern treatment nicotine replacement therapy is not feasible, unsatisfying and unusual (UK Government Statistics 2004). There is a growing need for a device that copies the same familiar features of the area are accustomed to smokers, but also copy the style and functionality of cigarettes and cigarettes. In addition, it is increasingly clear that there is a need for a system that satisfies the taste and sensory needs of the smoker, and the system, which is able to deliver nicotine in unmeasured dose, which the user can adjust according to your desire. Therefore one of the objectives of the present invention is the creation of non-cancer cigarettes, which is able to satisfy the usual, as well as the physical cravings of the smoker and may be socially acceptable form of nicotine replacement therapy. An additional object of the present invention is to provide a device with the dressing, which is more convenient, accessible and familiar form of nicotine replacement therapy, and which produces a faster-acting nicotine and can be easily integrated into existing formats of retail trade of tobacco, especially instead of changing legislation, which may outlaw the display of tobacco packaging in retail outlets.
With growing restrictions on cigarette Smoking in public places there is a possibility for a device that can mimic the physical act of Smoking and which is socially acceptable, so it can be used in all public places. In addition, there is a need for a device that can be used for the issuance of nicotine in nemurenai form or as a replacement for cigarettes, or focused on nicotine addiction, you feel smokers, thereby helping them to quit Smoking. Can be dosed other gaseous substances, such as oxygen, which are known to have a beneficial effect on the process of substitution of nicotine.
In the prior art Izv the walls a number of imitation cigarette devices for example, from US3631856, 3721240 and DE 4030257. All these devices are filled from a filling container.
In the publication W0 01/49349 describes a device for issuing oxygen in which the oxygen is stored in the container, which is then removed from the device and either fill or replace. However, not given any instructions on how to practice dressing.
US 3045671 describes a portable inhaler, having a camera that can be charged by the screw cartridge holder having a General cylindrical capsule on the end of the device which communicates with the chamber through the valve. An inhaler is designed to provide emergency oxygen for medical purposes and not designed as an imitation cigarette device.
In the US 417100 describes simulation cigarette device having a chamber filled with fibrous stored substance. A cylindrical pressure vessel containing an inhaled mixture is movable in the direction of the chamber for dispensing the material from the pressure vessel to the stored substance that allows you to breathe it in by the user.
According to the present invention is proposed simulation Smoking device containing imitation cigarette, having essentially cylindrical sivaramakrishna form, and supraven the e device having essentially rectangular case with a form, like a pack of cigarettes, containing a filling gas for imitation cigarettes, and having means to selectively hold the imitation cigarette.
By performing simulation cigarette like cigarette and filling device like a pack of cigarettes present invention closely copies the skill area. Thus, the user of cigarettes, probably easier to buy a product that has the appearance of cigarettes and cigarettes. In addition, the invention allows them to copy the ritual of extracting a cigarette from a pack and inhalation of the cigarette. It also allows the user to perform the ritual of filling, which is similar to the process of habit and action with the ignition lighter normal tobacco cigarettes. Therefore, the imitation cigarette device according to the present invention, most likely, will receive approval from smokers as a credible Smoking substitute and, in addition, can be easily adapted for sale through retail channels at points of sale, which are common for tobacco.
The housing preferably has a height from 44 to 176 mm, a width of 21 mm to 112 mm and a depth of from 8 to 60 mm, More preferably it has a height of from 80 to 120 mm, a width of from 20 to 60 mm and a depth of from 15 to 30 mm Opti is real he has a height of 88 mm, the width of 56 mm and a depth of 24 to fit a standard pack of twenty cigarettes sold through vending machines.
Imitation cigarette device preferably includes an elongated housing having an outlet for inhalation at one end and an inlet for filling the tank, extends along a significant portion of the casing and having the valve near the inlet for filling and discharge valve near the outlet for inhalation, which can be activated to allow gas from the reservoir to pass from the reservoir and out the exit to inhale.
The device preferably contains a gas tank having a discharge outlet and is coupled discharge valve of the tank, with the valve cigarette device is configured to communicate with the outlet valve of the tank to open the flow path from the reservoir filling device to the reservoir cigarette device.
The combination of device and filling unit may have sufficient capacity so that it sufficed for several days - depending on the nature of the use of normal use before you need to refill or replace the gas block. The tank from which ruled himself the unit could be, for example, a vending machine or a cylinder with higher Yes the population, the user can store at home or in your car so that it does not have to always carry it with you. However, the current preference is given to the sale of replacement petrol units, and not the making of blocks suitable for their postorna refills.
The tank has a volume of preferably from 500 mm3up to 10000 mm3and preferably from 2200 mm3up to 2600 mm3. Standard pressurized solution containing nicotine, solvent, propellant and oxygen is at a pressure preferably 2-150 bar (0.2 to 15 MPa), preferably 5-20 bar (0.5 to 2 MPa) and optimally 6 bar (0.6 MPa) Solution with a high percentage of oxygen is pressurized preferably from 5 to 150 bar (from 0.5 to 15 MPa), and preferably from 20 to 25 bar (from 2 to 2.5 MPa).
The device can usually get 8 to 24 puffs before you need to refill the tank.
The unit has a volume of preferably from 10000 mm3up to 100000 mm3and preferably from 40000 mm3up to 50000 mm3.
Standard the solution is under pressure 2-150 bar (0.2 to 15 MPa), preferably 5-20 bar (0.5 to 2 MPa) and optimally 6-8 bar (0,6-0,8 MPa). A solution with a high percentage of oxygen is pressurized preferably from 5 to 150 bar (from 0.5 to 15 MPa), and preferably from 20 to 30 bar (2 to 3 MPa).p> The unit can provide typically from 80 to 1000 puffs and preferably from 120 to 200 puffs before you need a refill.
The composition preferably contains oxygen, nicotine or its derivative or salt, antioxidant, aromatic and/or flavouring component, propellant, solvent. In addition, it may contain electoral reinforcing additive. The details of this composition are shown in concurrently pending application GB 0712308.6.
In addition, the tank may be equipped with a hand pump so that the pressure pump, which is driven by the lever or push the button located at the top or side filling unit fills almost the same as a handheld device associated with the cigarette lighter. This serves to fill and regulation of the reservoir, as well as to create a high pressure therein, so as to maintain a constant pressure and to give a constant dose.
The block is preferably provided with a counter doses to record the number of times of the refilling of the imitation cigarette and show it to the user. This gives a clear visual indication that the unit has used up its supply of gas, so that the user does not have attempted to fill the imitation cigarette from an empty gas block. Also, is it allows the user to have time to buy a new gas block before as the existing unit will use up its supply of gas.
It forms an independent aspect of the present invention, which in the broadest terms can be defined as a simulation Smoking device containing imitation cigarette and the device containing the gas and means to selectively hold the imitation cigarette, while the device further comprises a counter doses to record the number of times of charging of the simulation cigarettes and show to the user.
The device can be configured so that the means for selective retention of imitation cigarette holds a cigarette in the filling position. However, the means to selectively hold imitation cigarettes preferably with the ability to hold the imitation cigarette in position, which is different from the position in which seasoned imitation cigarette.
Department position, which is stored imitation cigarette, from the position in which it is charged, provides the designer the freedom to choose how to store cigarettes for ease of access, while at the same time also allowing convenient positioning the outlet of the filling device. In addition, it allows a closer copy of the impression of the application of this is common cigarettes, and packs.
It forms an independent aspect of the present invention, which in its broadest sense can be defined as a Smoking device containing imitation cigarette and the device containing the gas for imitation cigarette device and having means to selectively hold imitation cigarettes are made with the ability to hold the cigarette device in position, which is different from the position in which seasoned imitation cigarette.
Means for selective retention of imitation cigarettes preferably with the ability to fully accommodate the imitation cigarette inside.
Hold imitation cigarettes completely inside the enclosure provides a location very similar to traditional cigarettes.
It forms an independent aspect of the present invention, which in its broadest sense can be defined as a simulation Smoking device containing imitation cigarette and the device having a housing containing a filling gas for imitation cigarettes, and having means to selectively hold imitation cigarettes completely inside the case.
In addition, the present invention extends to a filling device for use with smoke simulation is inim device according to any of the above aspects of the invention.
In addition, the preferred features of one aspect of the invention are equally applicable to other aspects of the invention.
The unit can preferably contain one gas cylinder, but may also contain at least two cylinders, as it allows you to hold more gas in the package of convenient size.
In the case of two cylinders, they can be completely separated, so that the user fills cigarette device from a container. One balloon may be available outside of the refueling unit, and the other tank can be accessed from the inside. The cylinders may have the same orientation, or may be inverted relative to each other. However, preferably has a pipe and valve system, so that the cigarette charger is designed with refills simultaneously from both cylinders.
The unit can be supplied with a first gas line, which is filled cigarette device, and the second gas line, which filled the block. However, cigarette device is preferably filled on the same gas line, which is used for filling the gas block.
Cigarette device with oxygen forms the subject are simultaneously pending applications GB 0712304.5 and 0712306.0.
Now bude is described an example of a device and system according to the present invention with reference to the accompanying drawings, on which:
figure 1 - schematic view in section of the device also showing the nozzle;
figa is a schematic view in section of the distal end of the device with the filling valve in the closed position;
figw - view similar to the views of figa and showing the valve in open position;
figure 3 - schematic view in section, showing the trigger when the inhalation valve at the proximal end;
4 is a view similar to the view of figure 3 and showing an alternative construction is triggered when the inhalation valve;
5 is a view in section along the line V-V in figure 4;
6 is a schematic view in section of the first filling unit;
7 is a schematic view similar to the view of figure 6 and showing the second block;
Fig is a schematic view in section, showing the third block;
figa is a schematic view in section, showing the fourth block with imitation cigarette device in the initial position;
figw - view similar to the views of figa and showing the unit with simulation cigarette in the filling position;
figure 10 is a perspective view of the dose counter with a spatial separation of the parts and
figa-11S - schematic views in section of the counter doses in various stages of operation.
The system contains two main components, namely imit the traditional cigarette device 1, shown in figure 1-5, and the block 2 shown in Fig.6-8.
First will be described the imitation cigarette device 1. It contains an elongated hollow cylindrical body 3. One end of this housing is filling end 4, and the opposite end is diately end 5. At the filling end has a non-return valve 6, which is further described below. It leads to the reservoir 7, which continues for a considerable part of the length of the device. As shown in figure 1, the tank is limited by a cylindrical sleeve 8, is tightly inserted within the cylindrical body 3. But he could be limited by a cylindrical casing 3. At the end of the tank 7, opposite the filling end 4, and at a distance of about three quarters the length of the device from him is triggered when the inhalation valve 9, which is further described below. It leads to the outlet on vihalem the end of the 5. The tank 7 is periodically filled with gas through the check valve 6. The user then sucks on vihalem the end of 5, periodically opening signal when the inhalation valve 9 for retracting doses of gas from the reservoir 7.
Now describe in more detail the non-return valve 6 with reference to figa and 2B. This valve contains a shut-off element 11, a spring 13 is drawn in to the seat 12 of the valve. The spring 13 in its against the opposite end is supported by the support 14 of the spring, which is open to allow the passage of gas. In addition, the end of the 4 in front of the direction of the locking element 11 has a saddle 15 used in the dressing. In order to fill the tank, insert the nozzle 14 in the end 4 of the device 1. The nozzle 14 presses on the locking element 11 to raise from its seat, while the end of the nozzle firmly sits on the seat 15 of the nozzle, sealing the end of the tank during refueling operations. As shown in figure 1, the nozzle 14 is spring-loaded so that it automatically generates a gas when the pressure on the locking element 11. On the other hand, for charging may be provided by independent gas device.
During retraction of the nozzle spring 13 presses the locking element back into his seat to seal the end of the tank.
Now will be described signal when the inhalation valve 9 with reference to figure 3. It contains the locking element 16 in the form of an elongated rod with a through hole 17. This through hole 17 is located in a tubular discharge port 18 leading to the reservoir 7. In the position shown in figure 3, a through hole 17 is perpendicular to the outlet tube 18, thereby blocking flow through the tubular outlet 18. When turning the locking element 16 by 90°, a through hole 17 is flush with the pipe is atym the outlet 18, allowing flow from the reservoir 7.
The locking element 16 is held in the closed position shown in figure 3, clamped by a pair of springs 19. At each end of the locking element 16 has a blade system 20. Ahead along the blade system 20 is a pair of inclined 'inlet holes 21. They are located and oriented so that the air flowing through the inlet opening, hits on a blade system 20 in such a manner as to cause rotation of the locking element to the open position against the action of the clamped spring 19, thereby opening the valve. Thus, the valve is activated under the action of suction by the user on vihalem the end of the device. Upon termination of the suction clamped spring 19 causes the valve to close.
As can be seen in figure 3, there are two streams flowing towards vdyhatelnoy the end of 5. There is a flow of ambient air from the inclined holes 27, indicated by arrows 22, and the flow from the reservoir 7, which is passed through the through hole 17 and indicated by the position 23, with a pair of drainage holes 24 diverts part of the flow 22 of ambient air stream 23 and inclined forwards it, in order to facilitate the flow towards vdyhatelnoy the end of 5. This is done because the gas from the tank can be very cold, and, therefore, once ablaut ambient air of the threads 20. On vihalem the end is the grid 25 which holds in place the annular filter element 26 for a channel with an external thread and the Central filter element 27 to flow from the reservoir. They prevent the penetration of external contaminants into the device.
Now will be described an alternative implementation is triggered when the inhalation valve with reference to figure 4 and 5.
Most of the items on vihalem the end of the 5 are the same as the previously described elements, and marked the same positions. Differ only in the mechanism of the valve. It comprises a pair of plates 28, which are swivel mounted and preloaded in the first position, shown in figure 4, by means of an appropriate balancing of the spring 29. From each plate 28 in General are perpendicular to the sealing elements 30. Sealing elements 30 are preferably made of a material with some degree of elasticity, such as elastomer, or may be of rigid material with an elastic edge to edge to create a seal. Sealing elements converge in the middle of the tubular outlet 18 to hermetically close the path of flow through this outlet. In the device the air of the inclined inlet holes 21 hits the plate 28, causing them to rotate downwards from the position shown in f is g, thereby separating the sealing elements 30 and allowing flow from the reservoir 7. Upon termination of the suction plate 28 biased back to its original position shown in figure 4, and a tubular outlet 18 re-sealed.
Now will be described the first example of the refueling unit with reference to Fig.6.
The unit has approximately the same size and shape as the packs of cigarettes. This block has an essentially rectangular configuration. It is clear that may be allowed for some deviation from the strict rectangular shape, while still providing an essentially rectangular shape. For example, edges may be rounded or block may have a slightly curved configuration, making it easier to insert it into the pocket of the user. These changes, among others, are considered as being within the requirements for, essentially, a rectangular shape similar to the shape of a pack of cigarettes. The block is provided with a recess 31 in which you can store cigarette device 1, when not in use. The unit comprises a pair of gas cylinders 32 located on each side of the recess 31.
Each cylinder 32 has a similar construction. Each cylinder has an intake/exhaust valve, containing the locking element 33, which is preloaded to ETS is 34 valve clamped by the spring 35, supported on the support 36 of the spring.
To fill the cigarette device 1 out of the charging unit 2, and in order to fill himself the block 2, is provided by a wired system for providing hydraulic communication between the inlet/outlet hole 37 and the cylinder 32. It takes the form of a spring-loaded pipe 38 which leads from the inlet/outlet 37 to the two cylinders 32. The pipeline is equipped with a pair of nozzles 39, each of which is configured to press on the corresponding locking element 33 and each of which is equipped with a number of holes 40, allowing hydraulic communication between the inner space of the cylinder 32 and a spring-loaded pipe 38. Near the inlet/outlet 37 is a valve 41 of the pipeline, usually pre-loaded to the closed position by the spring 42. The nozzle 43 of the pipeline, similar to the nozzle 39, is connected with the valve 41.
When the relative positions in an unused state by a spring-loaded pipe 38 by a spring 44 is shifted to the position in which he is closely adjacent to the bottom of the gas block. At this time, the locking elements 33 are planted on the seat, and the valve 41 of the pipeline, each of them corresponding spring is preloaded in its closed position. When cigarette device 1 is inserted into the inlet/outlet 37, about the feats of the valve 6 on cigarette device 1 a, as explained above. The valve 41 of the pipe is pushed into the open position, and the spring-loaded pipe 38 by means of springs 45 is raised into the position shown in Fig.6. This causes the nozzle 39 to raise the locking elements 33 with their saddles. There is now a message from the hydraulic cylinders 32 in the reservoir 7 cigarette device. As gas cylinders 32 are at a higher pressure than cigarette device, the gas flows into the reservoir 7. Each cylinder 32 has a gas pressure sufficient for filling cigarette device 14 times.
When the cylinders 32 runs dry gas reserve, the unit can be thrown in the ideal case disposed of and replaced with a new unit. On the other hand, the cylinders can be re-filled. This is done using the same method as used for filling cigarette device of the cylinders. For this purpose, the high-pressure gas source (not shown) connected to the inlet/outlet hole 37 in the same way insert the cigarette device, and open a similar way to stream. Since the high-pressure gas source is at a higher pressure than the cylinders 32, it is air refueling. This is also done by way filled cylinders 32 for the first time.
Relies, for example, that the source of the IR high-pressure gas can be provided in the form of a vending machine, so that the user can fill his gas tank out of it, or may be a large gas tank, which the user can store in his house or car.
7 shows the second unit 2. It is similar to the first block, but in this case it is designed for filling cigarette device when the cigarette is in recess 31. Thus, the valve 41 of the pipe and the nozzle 43 of the pipeline inverted from their positions figure 6, the corresponding changes in the rest of the device. This allows you to automatically fill the cigarette device 1 when it is placed in the block.
On Fig shows the third block. This unit includes a housing 46 having a cap 47, which is pivotally connected to the hinge 48. When the cover is open, cigarette device 1 can be inserted into the recess 31 and learned from him. The block contains a single cylinder 32 made in accordance with the cylinders described in connection with 6. Since this example has only a single cylinder, intake/exhaust hole 37 is located directly under the nozzle 39 so that the cigarette device 1 and the high-pressure gas source pressure directly on the locking element 33.
Figure 9-11 shows the fourth refueling device is 50 and cigarette device 51. As in the previous examples, the device 50 has a housing 52, which is of such shape and size to be closely similar to a pack of cigarettes. The housing 52 has a cover 53, which is the angle in the upper part of the body. Cover 52 is attached to the housing 52 by a hinge 54 and has a curved side 55, which corresponds to the adjacent side 56 of the housing 52.
Cigarette device 51 is held in the recess 57 and a fully enclosed in it, when the cover 53 is closed, as shown in figa. Only the cylinder 59 is located inside the housing and contains respirable composition. The housing 52 has an opening 60, which is the filling opening. It can be protected detachable membrane to prevent access of dirt during transportation and storage. Near the wall of the casing is a plate 61, which may be depressed against the action of the spring 62 in order to have access to the stem 63 of the valve on the cylinder 59. This allows you to fill the cigarette device 51 as described above relative to the earlier examples.
The housing 52 has a window W, is shown schematically in figa and 9B, for a dose counter, which is further described below in connection with figure 10 and 11.
Plate 61 has a hanging protrusion 64 with many grooves 65. The plate 61 is located inside the hollow cylindrical body 66, having the th cut part 67, at the bottom of which is mounted a gear wheel 68 to rotate around the axis 69.
A cylindrical housing 66 is located inside the rectangular hole 70 in the slider 71. The slider 71 has a single tooth 72, 73 at each end and is located so that the inner edge 74 rests against the gear wheel 68. The ring 75 surrounds the slider 70. The ring 75 is equipped with a number of teeth 76 on its inner surface and the number 77 on its face outward surface. All items installed on the mounting ring 78 so that the lugs 79 on the housing 66 mate with corresponding protrusions 80 on the mounting ring 78, holding the parts in place.
In the case of use with pressure cigarette devices on the plate 61 shown in figv, the projection 64 moves down, the turning gear 68, which moves the slider 70 from the position shown in figa, to the position shown in figv. The tooth 72 on the slider 70 communicates with the corresponding tooth on the ring 75, thereby slightly rotating the ring 75 in the counterclockwise direction to the position shown in figv. Removing cigarette device causes the release plate 61 upward by the spring 62, so that the protrusion 64 rotates the wheel 68 in the opposite direction, thereby causing the slider to move to the position shown in figs and what oterom tooth 73 moves a little ring 75 further in the counterclockwise direction. Joint movement caused by pressing the cigarette device on the plate 61 and the withdrawal from it, is sufficient to promote ring 75 so that the window W is displayed next number in the sequence 77 digits. Therefore, this device can provide the reference in the reverse order of the number of doses that remain in the cylinder 59.
Can be used an alternative counters doses, for example, those that have an electronic device.
In addition, a large filling the balloon may be added to the system package on the valve". System package on the valve consists of an aerosol valve with welded package. If system "package on the valve" compressed air, oxygen, nitrogen or other gas in an aerosol container is on the outside of the package and acts as a propellant for a product that is in the package. This allows you to separate the active ingredients, such as nicotine, from the propellant is preferably oxygen - to promote more long term preservation. System package on the valve may be located inside a large container and can be supplied by the manufacturer, as, for example, EP Spray Systems or Power Container, and may have the same ability to refill as standard large cylinder under high pressure.
1. Simulation Smoking device, the content is the future of simulation cigarette, having essentially cylindrical sivaramakrishna form, and the device having essentially rectangular case with a form, like a pack of cigarettes, containing a filling gas for imitation cigarettes, and having means to selectively hold imitation cigarettes completely inside the housing in a position which is different from the position in which seasoned imitation cigarette.
2. The device according to claim 1, in which the imitation cigarette contains an elongated housing having an outlet for inhalation and the inlet for filling the tank, the continuing significant portion of the casing, and with the valve near the inlet for filling and discharge valve near the outlet for inhalation, which can be activated to allow gas from the filling device to pass from the filling device and outside exit to inhale.
3. The device according to claim 2, in which the device comprises a gas reservoir having a discharge outlet and is coupled discharge valve of the tank, with the valve imitation cigarettes are made with the ability to communicate with the outlet valve of the tank to open the flow path from the reservoir filling device to the reservoir simulation cigarettes.
4. Device according to any one of the preceding paragraphs, in which soprovojdayuschaya equipped with a counter dose in order to register the number of times of charging of the simulation cigarettes and show to the user.
5. The device according to claim 1 in which the means for selective retention of imitation cigarettes are made with the ability to hold the imitation cigarette in position, which is different from the position in which seasoned imitation cigarette.
6. The device according to claim 1 in which the means for selective retention of imitation cigarettes are made with the ability to accommodate imitation cigarette completely inside the case.
7. The device for simulation of crack device according to any one of the preceding paragraphs, having an essentially rectangular housing having a shape similar to a pack of cigarettes, and containing a filling gas for imitation cigarettes, and having means to selectively hold imitation cigarettes completely inside the housing in a position which is different from the position in which seasoned imitation cigarette.
SUBSTANCE: invention refers to medicine, particularly medical devices applicable for drug introduction in the form of inhalation, as well as a therapeutic simulator. The inhaler represents a smoking pipe wherein a pivoted lid tightly closes a liquid container. An entry of a portion of an outlet is truncated at the angle of 45-60° and arranged under the lid on a container axis. A disk is supplied on an annular groove on a lower portion of the container and gapped from the bottom. A cylinder outlet hole of the outlet is formed above the lid on an outlet stem with the outlet hole of the outlet and the outlet have supplementary tightly closed caps; and the gap of the disk and the outlet there is a smoothing chamber.
EFFECT: invention allows enhancing respiratory capacity of an individual.
9 cl, 7 dwg
FIELD: tobacco industry.
SUBSTANCE: invention relates to the process of biologically active and/or aromatic substances volatilisation for purposes of inhalable aerosol extraction in the course of the smoker imitating the act of a regular cigarette smoking. Gaseous products of combustion of flammable gas burnt (preferably - under oxygen excess conditions) partly or wholly, are supplied (in case of necessity - mixed with ambient air) through the biologically active and/or aromatic substances depot. The desirable temperature is selected by the gaseous combustion products content, in case of necessity - by the components ratio of the mixture of such gaseous combustion products with ambient air. The device for the method implementation includes a mouthpiece containing the biologically active and/or aromatic substances depot and a heating core. The core contains the body shell, a filling valve for filling a tiny gas reservoir with flammable gas, a regulator valve for controlled discharge of gas from the gas reservoir onto the burner and the substance converter for air heating with thermal energy generated by the burner. The mouthpiece is connected so that to enable its disconnection from the cigarette- or cigar-shaped heating rod for output of inhalable aerosol. Control of the regulator valve is performed by means of depression suction provided for on the mouthpiece and/or by means of air flow.
EFFECT: new smokeless cigarette substitute is proposed.
19 cl, 11 dwg
SUBSTANCE: invention refers to medicine and namely to devices for inhalation of various substances, preferably medicinal substances, to the human organism through airways. Inhalation cigarette consists of a cylindrical tube inside which there located is burnable filler, porous material with inhalation device and a filtering material. Cylindrical tube is made from heat-insulating material, covered on the outside with a thin antioxidant layer and consists of the rim made from cigarette paper on the side of the filtering material. Burnable filler is made in the form of chips which are covered on the outside with thin smoke agent layer. Polyolefine or granulated heat-resistant coal has been used as porous material. Acetate cellulose has been used as filter material. As burnable filler material, there has been used one of the materials of the group including calcium, aluminium, zinc, magnesium or their alloys.
EFFECT: invention provides thermal evaporations of inhalation substances, preferably medicinal substances without toxic impurities of pyrolised species of hydrocarbon substances.
2 cl, 1 dwg
SUBSTANCE: method involves introducing ozonized physiologic saline once a day during 30 min in addition to traditionally applied drugs. The ozonized solution has ozone in concentration of 100-150 mcg/l in the amount of 100-150 ml when treating children younger than 3 years. Children being elder then 3 years, ozone concentration is 200-250 mcg/l, its amount is 200-250 ml. The total therapy course is 5 days long. The traditionally applied drugs are not to be used within 30 min before and after ozonized physiologic saline application.
EFFECT: accelerated treatment course; no antibiotics being used; reduced risk of adverse side effects.
SUBSTANCE: method involves administering Surfactant BL in discrete small doses in addition to traditional therapy. Dose of 75 mg is dissolved in 2.5 ml of physiologic saline and introduced by means of bronchoalveolar nebulizer within 2 h three times at a dose of 25 mg.
EFFECT: enhanced effectiveness in treating pneumonia; prevented bronchial obstructive syndrome occurrence.
SUBSTANCE: inhaler has catalytic burner, fuel balloon 6 containing hydrogen, said balloon being connected to burner, reservoir 15 for inhaling additives such as aromatic substances and/or functioning substances, at least one inlet 2 for oxygen-containing gaseous mixture, preferably for air, and at least one outlet 3 for inhaling mixture containing aromatic substances and/or functioning substances.
EFFECT: increased efficiency and convenient usage of inhaler.
13 cl, 1 dwg
SUBSTANCE: there are disclosed method and composition for intensifying mucus excretion and treating pulmonary disorders, such as cystic fibrosis. They use together with osmotically active substance a synthetic pulmonary surfactant containing one or more pharmaceutically acceptable phospholipids mixed with SP-B polypeptide or its fragment, or polypeptide containing at least 10 amino acid residues and no more than about 60 amino acid residues, said polypeptide containing a sequence having variable areas of hydrophobic and hydrophilic amino acid residues presented by formula (ZaUb)cZd, wherein surfactant activity of mixed phospholipids and polypeptide higher than that of one phospholipid, has osmolarity varying between 220-1200 mOsm/kg, the concentration of free anions varying between 20-200 mmole/l and the pH value varying between 6.8 and 8.0, and the surfactant provides the pulmonary delivery of a daily dose varying between approximately 20 and 200 mg of total phospholipid equivalent.
EFFECT: invention provides intensified mucus excretion and improved quality of life in the patients suffering cystic fibrosis, bronchitis, bronchiectasis, ciliary diskinesia, COPD, or sinusitis.
15 cl, 2 dwg, 4 tbl, 4 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: invention relates to medicine, namely pharmacology. A pharmaceutical composition contains an active component selected from a group of pharmacologically active substances: having an effect on a central nervous system, peripheral neurotransmitter processes, cardiovascular system, coagulation system, neoplastic processes, metabolic processes, showing antibacterial activity, an excipient, cyclodextrin as a component ensuring high bioavailability, and a component modulating a duration of the pharmacologically active substance representing polymer. The pharmaceutical composition is presented in the form of a powder of particle size within 0.4 to 2 mcm. A method for administration of the pharmaceutical composition provides the pulmonary oral administration in the form of a dry or liquid aerosol with mass median aerodynamic diameter 0.8 to 2.0 mcm and degree of polydispersity 0.8 to 2.0.
EFFECT: ensured effective delivery of the pharmacologically active substances in the systemic circulation and alveolar inhalations of min 75% of solid or liquid aerosol particles.
5 cl, 5 dwg, 4 ex
FIELD: medicine, pharmaceutics.
SUBSTANCE: declared invention refers to chemical-pharmaceutical industry, and concerns new, taste-masking powders specified in a group consisting of biologically active substances for treating, relieving and preventing diseases in humans and animals, with average particle diameter d50 1 to 40 mcm and coating thickness 1 to less than 20 mcm of a hydrophobic coating material containing 50 to 90 wt % (relative to total powdered solid substance and coating material) with the hydrophobic coating material being wax of fusion temperature within 30 to 180°C, resin, polymethacrylate or its copolymer for inhalation or oral administration.
EFFECT: what is offered is a simple method for preparing and applying them for introducing the biologically active substances.
10 cl, 3 ex
SUBSTANCE: as an active substance, an aerosol contains aprotinin taken in the amount 23 to 30 mg in 100 ml of the preparation; a propellant is 1,1,1,2-tetrafluoroethane 70-84 vol. %; the solvents are ethanol 8-15 vol. %, glycerine 5-10 vol. %, water and a stabiliser is peppermint oil. The aerosol is pressurised in an aerosol container with a measuring valve.
EFFECT: preparation under the invention preserves native use and long storage antiprotease and antiviral properties of aprotinin.
6 cl, 2 tbl
FIELD: medicine; pharmaceutics.
SUBSTANCE: application of an antidepressant for manufacture of a medical product in the form of a dry powder for treatment of premature ejaculation, the corresponding way of treatment, an inhaler of dry poropps, containing a medical product of an antidepressant and a blister with an antidepressant (for example, tricyclic clomipramine depressant) for application in an inhaler of a dry powder are offered. The invention provides achievement of therapeutic effect during not more than 20 minutes at reduction of a dose and by-effects (in comparison with peroral intake of antidepressants). Thus bond deposition in a drink was less than 10%.
EFFECT: acceleration of achievement of therapeutic effect.
30 cl, 3 dwg, 3 tbl
SUBSTANCE: invention refers to chemical-pharmaceutical industry, and concerns pharmaceutical composition of metered aerosols containing antiasthmatic agents in the form of suspensions, solutions and emulsions. The metered aerosols are characterised with improved pharmaceutical properties and high storage stability. The pharmaceutical composition of metered aerosols containing antiasthmatic agents in the form of suspensions, solutions and emulsions, contains therapeutically effective amounts of Salbutamol or its salts, or formoterol fumarate or budesonide or beclomehasone dipropionate, propellent R 134A and target additives including ethyl alcohol, glycerine, isopropyl myristate, Tween 80, water.
EFFECT: suitable for treatment of various obstructive pulmonary diseases such as bronchial asthma, bronchitis, pneumonia etc.
4 cl, 12 ex
SUBSTANCE: ejection liquid is capable to stable ejection by means of the device using thermal energy. This liquid contains at least one substance chosen from the group, consisting of the proteins and peptides. Possibility of application of a liquid in the ink-jet device using thermal energy, improves addition at least one substance chosen from group, consisting of amino acids both their salts, and surface-active substance to the water solution containing at least one substance, chosen of the group consisting of proteins and peptides.
EFFECT: stability of adjustable ejection of an albuminous solution or peptide with obtaining of desirable volume of a microdrop.
14 cl, 9 dwg
SUBSTANCE: ejectable liquid which can be ejected stably in the way of the jet thermopress with thermal energy use even in case of presence is offered at least one component from proteins and peptides, and also the method and the device providing release of a liquid, containing at least one component from proteins and peptides, and providing use of the mentioned thrown out liquid are offered. At least one compound having the aminoethanamidine group is added in a water solution at least of one component from proteins and peptides for improvement of its qualities on a case of ejection in the way of the jet thermopress with thermal energy use.
EFFECT: stability of adjustable ejection of an albuminous solution or peptide with obtaining of desirable volume of a microdrop.
9 cl, 9 dwg
SUBSTANCE: sterile aqueous inhalation solution containing active substance Tobramycine. Preparation of invention is offered with high content of active substance (approximately 80 to 120 mg/ml Tobramycine). Preparation also contains acid adjuvant and has low content of sodium chloride (maximum approximately 2 mg/ml). Preparation can be injected or introduced as aerosol with e.g. common sprays.
EFFECT: suitable for application in combination with recent sprays with vibrating membrane and gives the chance for application of an individual therapeutic dose.
24 cl, 1 tbl, 7 ex
FIELD: medicine; pharmacology.
SUBSTANCE: invention can be applied for treatment of asthma and associated disorders, specifically for treatment of chronic obstructive lungs disease. This composition contains specific anticholinergic agents, antagonists of β-2 and corticosteroids.
EFFECT: favourable and improved asthma treatment.
33 cl, 43 ex
SUBSTANCE: liquid for forming aerosol which is used as a solution of aromatic substance contains basic components and adipic acid which is added to the basic components. The basic components include a solvent and a lipophilic aromatic substance containing L-menthol dissolved in the solvent. The solvent is propylene glycol.
EFFECT: use of the liquid enables formation of a significant amount of aromatic aerosol, having long life.
4 cl, 2 dwg, 2 tbl, 6 ex