Coal-plastic composition for bone defects elimination

FIELD: medicine; maxillofacial surgery.

SUBSTANCE: coal-plastic composition for bone defects elimination includes carbonic material "ТГН-2М"and polyamide film 12/10. Silver powder is additionally introduced; the ingredients proportion being as follows, in wt %: carbonic tissue "ТГН-2М" 57.5-62.5, silver powder 2.5-7.5, polyamide film 12/10 the rest. Silver powder particles size is 20 to 50 mcm.

EFFECT: radiodensity and biocompatibility increase, toxicity and carcinogenicity lowering, gaining anti-inflammatory and antiseptic properties.

2 cl, 1 tbl, 3 ex

 

The invention relates to medicine, namely to oral and maxillofacial surgery, and can be used to correct bone defects.

Known composition of the carbon fiber to correct bone defects "ASTEC", which contains carbon fabric TGN-2M, polyamide film 12/10 in the following ratio, wt.%:

Carbon fabric TGN-2M65
Polyamide film 12/1035

representing the press pack, consisting of alternating between the carbon cloth TGN-2M, 100×100×034-7 layers;

polyamide film 12/10 in the form of a film of 100×100×0.2 to 7 layers (TU 48-4807-22989).

However, this material "ASTEC" for all its positive qualities has one serious drawback - it radiolucent with all the ensuing consequences: when Troubleshooting various bone defects in humans carbon material "ASTEC" during the control study x-ray images and CT scanning of the carbon material is not rendered. In the postoperative period it is impossible to trace the fate of carbon implants placed during operations.

The closest to the invention is a composition of carbon to eliminate the Def is mswb bones, containing carbon fabric brand TGN-2M, polyamide film 12/10 and the metal powder of boron in the following ratio, wt.%:

Carbon fabric TGN-2M45-65
The metal powder of boron
with a particle size of 20-50 microns2-20
Polyamide film 12/10rest

[RF patent N2241495, A61L 27/08, A61F 2/28, 2003].

The disadvantage of carbon with boron powder is that he was not visualized on spiral computed tomogram and not visible at all when x-ray examination, which complicates the postoperative monitoring of installed carbon material in the human body. Also in the study of patients on spiral computed tomography increases the radial load several times. The boron powder in large quantities is toxic to living organisms.

The technical result of the present invention is to increase rentgencontrastnoe and biocompatibility, reduced toxicity and Carcinogenicity, the emergence of anti-inflammatory and antiseptic properties of the material.

The technical result is achieved by the fact that the composition of the carbon fiber to correct bone defects, the soda is containing carbon fabric TGN-2M, polyamide film 12/10, the distinguishing feature is that it additionally contains a powder of silver in the following ratio, wt.%:

Carbon fabric TGN-2M57,5-62,5
Powder silver2,5-7,5
Polyamide film 12/10rest

It is desirable that the particle size of the silver powder was 20-50 microns.

The proposed structure of the carbon fiber has high physical and mechanical properties, high use of rotary instruments, not toxic, not carcinogenic, anti-inflammatory and antiseptic properties.

Silver has a density of 9.8 g/cm3possesses excellent chemical resistance, stable in air up to temperatures 197°With regard to heat and increased pressure that leads to oxidation, has the ability to suppress pyogenic flora in biological tissues. The silver powder is evenly dispersed between the layers of fabric and polyamide and perform thermomechanical processing package, the following technologies. Silver retains its original properties and is in the form of mechanical impurities in the pores of the fabric.

Example 1.

The material was obtained as follows: 62,5 g carbon fabric brand TGN-2M Perella is to see 35 g of polyamide film 12/10, between which evenly distribute 2.5 g of silver powder with a particle size of 20-50 microns. Thus, the obtained material consisting of alternating between the layers of carbon fabric brand TGN-2M, 100×100×034-7 layers, polyamide film 12/10 100×100×0.2 to 7 layers and powder of silver 20-50 microns, uniformly distributed between the fabric and polyamide film, is subjected to hot pressing at a temperature of 210±5°C, a pressure of 100 kg/cm2and the shutter speed is 1 hour. Properties of carbon fiber are shown in table.

Example 2.

Material consisting of 60 g of carbon fabric brand TGN-2M shift 35 g of polyamide film 12/10 and 5 g of a silver powder with a particle size of 20-50 μm, respectively, subjected to hot-pressing as in example 1. Properties of carbon fiber are shown in table.

Example 3.

Material consisting of 57.5 g of carbon fabric brand TGN-2M shift 35 g of polyamide film 12/10 and 7.5 g of a powder of silver, is subjected to hot pressing in example 1. The ratio of the components of the material are 57,5:35:7,5 respectively. Properties of carbon fiber are shown in table.

Technological equipment allows us to produce blanks of size 20×200×300 mm, made of implants, machining according to drawings or casts applied individually to the patient.

Adding more than 7.5% of a powder of silver begin to change specified physico-chemical properties of the carbon material, if you add less than 2.5% of silver powder material is not radiopaque and the surgeon will not be able to trace its fate, the degree of wear. Also, the material does not have sufficient anti-inflammatory and antiseptic properties.

Table
Physico-mechanical properties of CFRP "ASTEC" and "Osaka with boron and Osaka with silver.
№ p/pProperties"ASTEC""ASTEC" with the addition of boron"ASTEC" silver
2%4%6%8%12%15%2,5%5%7,5%
1Density, g/cm21,161,181,201,231,261,331,362,043,03,06
2Porosity, %36,933,7 30,126,2a 21.516,814,717,212,17,8
3The modulus of elasticity, MPa × 1031,831,91,941,971,992,022,053,663,72the 3.65
4Strength, MPabending49,6a 50.551,351,552,654,1of 56.473,069,561,1
compression13,114,616,317,919,2of 21.222,736.937,3to 43.1

The table shows that in the comparative analysis of the material "ostec and ASTEC with additions of boron and proposed composition "ostec with the addition of the silver density of the material in the proposed structure more than in the known plastics "ASTEC". Also the table shows that increasing the percentage of additives of boron and silver density of the material increases, the porosity decreases, the modulus of elasticity increases, the compressive strength and bending also increases.

Thus, PR is lagueny composition with the addition of silver (density visualization on a scale of Hounsfield 800-900 units) in comparison with the known "ostec with additions of boron (density visualization on a scale of Hausfeld 70-150%) have greater use of rotary instruments. "ASTEC" without additives has no roentgenocontrast (density visualization on a scale of Hausfeld 0 ed). The boron content in the article "ostec with additives of boron reaches 12-15%, which affects the biocompatibility of the material, the toxicity and Carcinogenicity. Moreover, the visualization of this material is possible only with the use of spiral computed tomography in a special programming mode, while the radial load increases several times. In addition, increases the cost of radiodiagnostics.

The proposed composition with less silver content has good visualization using x-ray methods. Also this material has a sufficiently high anti-inflammatory and antiseptic properties, is biocompatible, non-toxic and not carcinogenic. The material is not observed corrosion phenomena, it is resistant to fatigue damage, low amount of wear and elasticity is close to the elasticity of the bone and close to the conductivity of the tissues of the human body.

1. The composition of carbon for the removal of defects of bone, containing carbon fabric brand TGN-2M and polyamide film 12/10, characterized in that the composition additionally contains a powder of silver in the following ratio, wt.%:

Carbon fabric TGN-2M57,5-62,5
Powder silver2,5-7,5
Polyamide film 12/10Rest

2. The composition of the carbon fiber to correct bone defects according to claim 1, characterized in that it contains a silver powder with a particle size of 20-50 microns.



 

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24 cl, 8 ex, 3 tbl

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