Composition material for osseous tissue replacement

FIELD: medicine.

SUBSTANCE: invention relates to composition materials used in making endoprosthesis and in using the composition material for replacement of osseous tissue. The composition material for replacement of osseous tissue comprises a porous matrix made of carbon fiber and carbon material - a filling agent filling pores of matrix partially and wherein the interplanar distance d002 in carbon material crystal is 3.58-3.62 Å, and the interplanar distance d002 in carbon crystal-a filling agent is 3.42-3.44 Å in the total amount of carbon fiber 20-80%. Invention provides enhancing strength and safety of junction of endoprosthesis material with osseous tissue due to creature of the composition material for replacement of osseous tissue with the elasticity modulus equal with the human and animals elasticity modulus in the range 14-28 hPa.

EFFECT: improved and valuable properties of material.

1 tbl

 

The invention relates to the field of composite materials and can be used in medicine for the manufacture of implants.

Known composite material for bone tissue substitution, comprising a porous structural element with a pore diameter of not more than 200 microns of carbon fiber and carbon material filler, partially filling the pores so that they were less than 200 microns in diameter. The porous structural element of carbon fiber and carbon material filler to form a product that can be used as a prosthetic device for replacement of bone tissue of humans and animals (see the description of the invention to the U.S. patent No. 5981827 from 02.11.97).

This invention made as a prototype.

The lack of technical solutions of the prototype is unacceptably high modulus of elasticity and a lot of it spread to obtain the composite material.

The modulus of elasticity of the bone lies within 14...28 HPa, while the modulus of elasticity of the technical solution of the prototype can reach 30...150 HPa, i.e. to exceed the modulus of elasticity of the bone and more. Prosthetic device for replacement of bone tissue (prosthesis)made of such material is very hard and when installed in a living organism, due to the different values of the deformation of the material is s endoprosthesis and bone, there is a constant relative movement of the mating surfaces, which leads to a gradual loosening of the endoprosthesis and the absence of conditions for free germination of bone tissue into the pores and the relief of the material of the endoprosthesis.

Simultaneously, the pair of hard surfaces with healthy bone causes the so-called order healthy bones and inhibits the creation of homogeneous new bone.

The task of the claimed invention is to provide a composite material for bone tissue substitution with modulus equal to the modulus of elasticity of the bone tissue of humans and animals and lying within 14...28 GPA. This task is achieved by the fact that in the composite material for bone tissue substitution containing a porous matrix of carbon fiber and carbon material filler, partially filling the pores of the matrix, interplanar distance (d002crystal carbon fiber is to 3.58...3,62 Angstrom, and the interplanar distance d002crystal carbon-filler - 3,42...3.44 Angstrom, with a total number of carbon fiber 20...80%.

When the interplanar distance of the crystal, carbon fiber, carbon filler, and the content of carbon fiber in the range beyond the stated limits, takes place in the composite material for bone replacement TC is neither exceeded for humans and animals in the elastic modulus of bone.

Composite material was made as follows: carbon fiber-made frame products, similar in form to the replaceable part of the bone. This pre-sets the orientation of the fibers, the best way for implant under load. Then the skeleton is impregnated carbon filler to achieve the necessary porosity. Impregnation can be achieved by different technological methods, for example by decomposition of methane at temperatures of 900°-1000°C. Final finishing of the product is made by machining.

The invention is illustrated by the following examples.

Were prepared and tested (defined modulus of elasticity) samples of composite material for bone tissue substitution, which were applied:

- carbon fiber having crystals with d002that Å

1 - to 3.58

2 - 3,60

3 - 3,62

4 - 3,45

5 - 3,68

- carbon compound having crystals with d002that Å

1 - 3,42

2 - 3,43

3 - 3,44

4 - 3,38

5 - 3,48

- the content of carbon fiber, %

/table>

The results of the tests are presented in table 1

1-207-19
2-558-25
3-809-40
4-1010-85
5-1511-90
6-17
26
Table 1.
no experienceInterplanar distance of the crystal carbon fiber d002that ÅInterplanar distance of the crystal carbon filler d002that ÅThe content of carbon fiber, %The modulus of elasticity, GPAResult
13,683,388555-
23,683,381938-
3to 3.583,432028+
43,623,448018+
53,453,381772-
63,683,488540-
73,683,4810112-
8to 3.583,425519+
93,623,4440+
10to 3.583,442524+
113,623,422521+
123,603,448016+
133,623,428014+
143,453,388564-
153,453,481550-
163,453,489092-

Test results reported in table 1, it is seen that at interplanar distances of crystals of carbon fiber and carbon filler, and the content of carbon fiber, which is in the claimed range, the modulus of elasticity of the composite material is acceptable for human and animal within - examples 3, 4, 8, 9, 10, 11, 12, 13 (the modulus of elasticity is 14...28 HPa), when you exit the claimed range is unacceptable increases - examples 1, 2, 5, 6, 7, 14, 15, 16 (the modulus of elasticity is 28...112 HPa).

The positive effect from the use of the invention is to increase nade the particular connection of the material of the implant with the bone tissue due to the composite material to replace bone tissue elastic modulus, equal to the modulus of elasticity of the bone tissue of humans and animals and lying within 14...28 GPA .

Composite material for bone tissue substitution containing a porous matrix of carbon fiber and carbon material filler, partially filling the pores of the material, characterized in that the interplanar distance d002crystal carbon fiber is to 3.58...3,62 Åand interplanar distance (d002crystal carbon - filler - 3,42...3,44 Åwhen the total number of carbon fiber 20...80%.



 

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