The method of obtaining biologically active aqueous compositions of biologically active water composition and installation to obtain

 

The invention relates to the production of water of biologically active compositions based melt condensate resulting from the freeze-drying of protein products may be used in pharmaceuticals, cosmetics, food industry and so on, the Method of obtaining water biologically active composition based on melt condensate formed as a result of freeze-drying the protein products includes the following stages: a) freezing the protein product, (b) cooling the shelves for products, cameras sublimator and desublimator with carrying out the condensation of atmospheric moisture on the evaporator of sublimator, download the frozen product in the chamber of sublimator, g) freeze-drying of the product with simultaneous condensation of the vapor product on the evaporator desublimator; d) discharging the dried product with its subsequent preservation or packing; (e) the defrosting of the evaporators of sublimator and desublimator obtaining melt condensation of atmospheric moisture and biologically active aqueous composition; W) drain condensates obtained. The water composition obtained by the above method, characterized natural ultrafiltration, molecular-structured the taste 0-2 points, the smell of 0-2 points, chromaticity 0 gradation, the turbidity of 0 mg/L. device for producing the above composition contains sublimator with the evaporator for condensing atmospheric moisture, which is connected with a vacuum pipe with desublimation with the evaporator for condensing biologically active water compositions, coupled with the evaporators of the refrigeration unit, connected with the vacuum pipe vacuum unit and separated from each other fixtures to drain thawed condensates specified water composition and atmospheric moisture, these evaporators are connected with the possibility of alternate first and both evaporators. The invention allows to extend the capabilities of existing technology and equipment designed for sublimation protein products and to obtain high-quality, purified from impurities, moisture and unwanted particles in the aqueous composition. 3 S. and 17 C.p. f-crystals, 4 Il., table 2.

The group of inventions relates to the production of water of biologically active compositions based melt condensate formed as a result of freeze-drying biological (Belkova the treatment of these compositions, and can be used in pharmaceuticals, cosmetics, food industry and so on

At present, both in our country and abroad are widely used various methods of drying biological (protein) products, namely: convective-vacuum pulsed, infrared radiation, convective, conductive, microwave, freeze, cryogenic.

The main objective of all these methods of drying is the removal of moisture from biological (protein) products using those or other physical processes.

Technologically, all currently known plants operating using the effect of sublimation, is divided into 10 main stages:

1) pre-treatment of the product;

2) the freezing of the product;

3) the cooling chamber sublimator;

4) loading the sublimation chamber;

5) drying;

6) unloading of dry product;

7) preservation or packaging of the product;

8) defrost evaporators;

9) drain condensate;

10) washing machine.

These technologies and devices are widely represented in the prior art (see, for example, SU 1784088, EN 2115024 and EN 2119622).

Cleaned and prepared product is subjected to pre-freeze in cells with temperature not exceeding ermetico the lid and begin the drying process.

In the process of drying, the product is treated three main components: the cold, the temperature of the heated product and the vacuum.

When setting in the freeze-drying chamber operating pressure is heated shelves with frozen products. Drying of biomaterials in this mode is accompanied by an intense sublimation of the ice, i.e. the transition of water from liquid to vapor, bypassing the liquid phase. Wet steam passing through desublimator condenses on the evaporator in the form of ice (drained), and neskondensirovannyh pairs by means of the vacuum pump are released into the atmosphere. As a result, the evaporator desublimator ice is formed, the thickness of which increases as the drying of the product. The amount of ice formed during the drying process, approximately 80-95% of the volume of the moisture contained in the product before drying. Reaching the desired humidity of the product, do unloading of the finished product. Ice condensate formed as a result of desublimation, subjected to forced defrost and melt liquid is discharged into sewage communication. Thus, the melted condensate containing not less than 95% water, and is considered to be a waste of this process.

None of idaltu production of secondary product, and in some cases, and the main - aqueous biologically active composition formed in the drying process of foods of plant origin.

The present invention is the receiving water a biologically active composition, cleaned of impurities of atmospheric moisture and particles of the product, to use it as a product market with the possibility of application in the Pharmacopoeia, cosmetology, food and other industries.

The technical result of the invention consists in expanding the capabilities of current technology and equipment designed for sublimation biological (protein) products with the aim of obtaining high-quality, purified from impurities, moisture and unwanted particles of bio water composition.

This task and the technical result are solved by the method of obtaining water biologically active composition based on melt condensate formed as a result of freeze-drying biological (protein) products, including the following stages:

a) the freezing of biological (protein) of the product

b) cooling the shelves for products, cameras sublimator and desublimator with carrying out the condensation of the steam is

d) freeze-drying the product with simultaneous condensation of the vapor product on the evaporator desublimator;

d) discharging the dried product with its subsequent preservation or packing;

e) the defrosting of the evaporators of sublimator and desublimator obtaining melt condensation of atmospheric moisture and biologically active water compositions;

f) draining condensates obtained.

In private embodiments of the invention the problem is solved by the fact that before freezing carry out a preliminary preparation of the product by washing and subsequent complete removal of moisture.

In the process of freezing of the product of stage (a) it is placed in the pan. Pallets covered airtight lids, made of stainless steel with a sealant, such as silicone rubber.

During the drying stage (g) require the freezing of the melted when loading product and additional condensation of atmospheric moisture on the evaporator of sublimator.

During the drying stage (g) carry out cleaning of the vapor product from the biological particles (protein) product using a filter.

During the drying stage (g) is necessary to depressurization of sublimator on imator should be made through a separate filter.

Draining of condensate in step (g) is produced through various drain pipes.

Drain water biologically active composition is carried out in sterile container.

Draining of melt condensation of atmospheric moisture is carried out in sewage communication or use for technical purposes.

After step (g) conduct the washing machine.

The task is also solved most of the water biologically active composition based on the melt condensate obtained from cells and tissues biological (protein) products, characterized by the fact that she received in accordance with the above method.

The composition has the following physical properties:

Natural ultrafiltrate;

Molecular structure similar to ice;

Superior absorbency;

and the following organoleptic characteristics:

Taste 0-2 points

The smell of 0-2 points, for example, natural,

inherent in the dried product

Color 0 gradation

The turbidity of 0 mg/l

The problem is solved using the installation for the production of biologically active aqueous compositions containing sublimator with capacitor atmospheric moisture, which is connected with a vacuum pipe with desublimation with conteny with vacuum piping vacuum unit and separated from each other fixtures to drain condensates specified water composition and atmospheric moisture, these capacitors are connected with the possibility of alternate first and both evaporators.

Both evaporators are connected through a temperature controlled valves, solenoids, and an adjustable valve, forming a distribution system with refrigerant.

Sublimator contains sublimation chamber with an airtight cover, installed in the chamber shelves to accommodate pallets of product with covers, with shelves made with the possibility of heating the capacitor atmospheric moisture, the filter vapor product, installed at the entrance to the vacuum pipe, a tray for collecting melt condensation of atmospheric moisture and a device for draining naturally melt moisture.

Cover pallets can be made of stainless steel and equipped with a seal, for example, of silicone rubber.

Sublimator equipped with a fan and an additional sterilization-sustelnet filter.

Desublimator contains desublimation camera, condenser biologically active aqueous composition and a device for draining water biologically active composition.

When this capacitor biologically active water compositions can be ipotecaria, mounted coaxially to the evaporator in the upper part.

Desublimator equipped with a surge tank for liquid shirt and a device to drain it.

The vacuum pipe can be provided with an air separation cutoff and sterilization-drying filter, established on the site of the vacuum pipe between the air separation cutoff and the entrance to desublimator.

It is well known that water is quantitatively predominant among the chemical compounds that comprise living organisms. Its content during the active life of the average 70-95% of the wet weight. It is water because of their unique physico-chemical properties is the universal internal environment, in which only happen and life processes, it is, according to the figurative expression of the famous biologist A. St. diardi, “matrix of life”.

To a selected moisture, and that 50-85% of the initial weight of the product is still not treated as product drying, so her collection and the possible further application was not given proper attention, although it is clear that this is a valuable product that has undergone a natural filtration on a cellular level.

In the analysis of different methods of drying it was found that when the vacuum is water, filling cells and tissues dried biological (protein) of the product.

After defrost icy condensate is formed of biologically active water composition.

Why track? The concept of sublimation (evaporation) in relation to this process means the transfer of moisture from the solid state into vapor, bypassing the liquid phase. At some stages of drying, the evaporation takes place very rapidly, pair removed, pull moisture particles of the product and are condensed together in desublimator.

In addition, there is a partial evaporation of aromatherapy components of the product, such as alcohols, ethers, aldehydes, and others, also formed in desublimator.

One of the most important properties of biologically active water of the composition is improved absorbency. This property of the composition indicated in connection with the fact that inland water environment of all living organisms sequenced at the molecular level and resembles the structure of ice. Water in the structural condition of the ice is a vital condition of the main bioenergetic processes in the living body. Conventionally, the house, built of blocks requires to build a much smaller energy than a house built of bricks is nom, disordered form like loose bricks, you need to expend on its organization, streamlining the structure of the ice, so she could take his place, to take part in the synthesis of living matter in the so-called bio-energetic processes in living cells. On the other hand, when the water enters the body in a pre-ordered in the structure of ice. This water is easier to penetrate through the cell membrane and significantly faster enters into interaction with the substance cells without unnecessary expenditure of energy.

Range of manufactured products prepared using the method of freeze-drying, is very wide: it's all kinds of cereals, soups, meat soups, boiled meat, milk, dairy products, vegetables, fruits, and so on

As biological (protein) products for drying them by sublimation with a parallel production of biologically active aqueous composition suitable mostly foods of plant origin. This is because the technology of advanced products preparation (stage 1) is not of plant origin before freezing (stage 2) in some cases involve heat treatment (boiling, steaming, add the product, created by nature - replacement of domestic water environment of the cells and interstitial water of the water in which occurs the preparation of this product. Thus, foods that have undergone heat treatment, do not satisfy the basic condition of receiving the proposed decision biologically active aqueous composition having a constant internal water environment dried product.

On the other hand, the products suitable for freeze drying with simultaneous production of biologically active aqueous composition can be any products of vegetable or animal origin, not the past thermal or other treatment violating natural internal water balance of the product. Of products of plant origin that almost all vegetables, fruits, herbs, algae. Of products of animal origin are the most obvious milk, sour serum, milk products.

After defrosting condensate formed a turbid liquid with the smell of dried product, which is present in dissolved form and in the form of sediment particles dried product. Depending on the form of dried products of the chemical composition of the liquids will be different. P is Auda compositions.

Below is the approximate composition of biologically active compositions obtained from products of vegetable and animal origin, such as beets and eggs.

From beet:

Water - of 99.5-99.9%, the remaining 0,5-0,1% made up, %:

Carbohydrates 71,9

Proteins 7,2

The rest (vitamins, mineral

elements, amino acids, fiber,

volatile aromatic substances and other) 20,9

Of eggs:

Water - of 99.5-99.9%, the remaining 0,5-0,1% made up, %:

Proteins 45

Carbohydrates 7,1

Fat 37,3

The rest (vitamins, mineral

items that are volatile aromatic substances and other) to 10.6

To lose such a quality product, which is obtained by sublimation of products of plant origin biologically active aqueous composition containing more than 99% pure, it is impractical, because to fill their own water resources, particularly plants, absorbing water from the soil, and then conveying it to their cells and tissues, produce the so-called ultrafiltration water quality which is hard to overestimate.

It is the way to obtain this water biologically active composition, the composition containing a certain amount of aromatics product, missive is arranged this song in refined form, and are the object of the invention.

The invention is illustrated by drawings, where Fig.1 shows a device for producing biologically active aqueous composition (General view); Fig.2 - site evaporation and vacuum parts of the installation according to Fig.1; Fig.3 - node distribution of the refrigerant between the evaporator; Fig.4 - capacity placed in her bioproduct.

In an advantageous embodiment, the installation (see Fig.1) consists of sublimator 1 with a cover 2, desublimator 3, the vacuum pipe 4, the vacuum pump 5, the refrigerating unit 6 and control unit 7.

Sublimator 1 (Fig.2) consists of sublimation chamber 8 located therein shelves 9 for products and condenser (evaporator) 10 to condensation of atmospheric moisture with a fan 11, wall 12 to delay the condensation of atmospheric moisture and a device 13 for draining condensation of atmospheric moisture. Sublimator 1 through the vacuum pipe 4 is connected with desublimation 3 with removable cover 14. In desublimator 3 has a cylindrical condenser (evaporator) 15 double walled stainless steel, designed for condensing vapor of the product. Between the walls is the coil 16 and to improve the heat transfer of the empty spaces is

The moisture from the vapor product is condensed on both sides of the specified evaporator 15, which in comparison with the known evaporators allows for the same internal volume desublimator to increase the surface area of the evaporator is more than two times. For a more complete vapor recovery product and uniform distribution of the condensate on the surface of the evaporator 15 is installed fairing 18. After defrost condensate water formed composition flows down through the drain hole 19, and draining liquid shirts through hole 20. Filling maintenacne space liquid-shirt by using the expansion tank with level indicator of alcohol (Fig.2 not shown). Outside desublimator 3 is covered with the insulating layer, of a thickness not less than 10 cm, and through the pipe 21 is connected to a vacuum pump 5. In the upper part of the sublimation chamber 8 at the input of the vacuum pipe 4 is located a filter 22 for delaying solids dried biological (protein) of the material. Both of the evaporator 10 and 15 are connected through the coils 23, 24 and 25 (Fig.3), an adjustable valve RV indicated by the position 26, and thermal expansion valves TRV position 27 and TRW position 28, and Takuo compressor 6. On the vacuum pipe 4 is installed separating the vacuum cutoff 31 and drying-sterilizing filter 32, provided with a valve 33 of the inlet air. Sublimator 1 can also be equipped with a drying-sterilizing filter (Fig.2).

The specified filter include in the work if you want to create in sublimator advanced sterilization and reduced levels of humidity.

The idea is embodied in the principle of freeze-drying of biological (protein) products subjected to drying, only to be removed moisture, so the resulting condensate at 100% should consist of water that fills the cells and tissues of biological (protein) of the product.

But due to physical and technological features of the process in the condensate are impurities, consisting of a light aromatic product fractions, atmospheric moisture and particles of dried biological (protein) of the product, so after defrost water composition has a turbid appearance and may even precipitate.

To empower sublimation machines, namely, the obtaining of aqueous compositions on an industrial scale and its further communication to the standards of cleanliness and sterility requirements for food and meditsinskii even primary product production, you should use the following design changes, allowing you to make basic cleaning of impurities on the stage of drying.

To do this:

a) to prevent the ingress of atmospheric moisture in the aqueous composition to use design evaporator made according to Fig.2, to install an air cutoff 31 and drying-sterilizing filter 32;

b) to prevent particles of the product in desublimator to use a filter 22 for particulate dried product.

To obtain the aqueous composition with a minimized content of atmospheric moisture are encouraged to use desublimator dual evaporator made according to the scheme depicted in Fig.3.

The meaning of the modification of the evaporator of desublimator is that at different stages of drying to include the work of one or both of the evaporator together. It is possible to achieve distributed desublimate atmospheric moisture and vapor drying of the product, which ultimately allows you to get water biologically active composition with a minimal content of atmospheric moisture. Phased operation of the proposed design is illustrated with the following example.

The first stage of drying, prepare the e camera sublimator and desublimator to a temperature of minus 30-40 degrees (stage b) by carrying out the condensation of atmospheric moisture. For this purpose the 1st branch of the evaporator consisting of a solenoid 23, thermostatic expansion valve TRV 27, evaporator 10 and thermatron 34 (see Fig.3). The work of this branch of the evaporator similar to the typical evaporator. Its purpose is cooling chambers desublimator and sublimator with shelves for products, and the condensation of atmospheric moisture from the air trapped in the cells.

The next step is to download the frozen product into the chamber (stage b). In accordance with Fig.4 frozen bioproduct 35 stacked on the pallet 36, remove the sealing plate 37 made of stainless steel, in which the gasket 38 used silicone rubber. The pallet 36 set on the shelf 9.

At this stage the air again enters sublimator, because for download products require depressurization. After loading sublimator tightly closed with the lid, and as when loading large volumes of production inevitably her little, to continue drying, you must wait at least 30-60 minutes for freezing the melted areas. At this stage in the work involved, too, only the evaporator 10 in connection with what is required re-precipitate atmospheric moisture.

The third stage drying (tasadays all the moisture, contained in the product. In order for the drying process to prevent evaporation of atmospheric moisture from the evaporator 10 and disablereuse it to the evaporator 15, fitted with an additional adjustable valve RV 26 (Fig.3). He adjusts the temperature required to maintain atmospheric moisture in a frozen state. Temperature podmorazhivanija is determined experimentally:

the thickness of the condensation of atmospheric moisture, obtained in the previous stages, should not decrease, most likely, inevitably even a slight increase in the volume of the condensate due to partial vapour deposition dried product to the evaporator 10.

Structurally, the evaporator 15 is the main desublimation, so it must be run in separate containers with tightly fitting lid and drain to drain biologically active water compositions, and to provide for the possibility of sterilization. The evaporator 10 and the support, its main purpose is cooling shelves, sublimator and deposition of atmospheric moisture, it must be placed in sublimator, complete with a tray for collecting the melted condensate, and equip a separate sink.

Table 1 shows the state of the solenoid Venti is limachi evaporation takes place very rapidly, therefore, a pair of removed moisture vomit particles of the product, a part of them gets in the condensate, as part of the flow neskondensirovannyh vapor released into the atmosphere.

To avoid contamination of the condensate particles of the product will help filter 22 is installed in sublimator at the entrance of the vacuum pipe. To the degree of clogging of the filter does not have a big impact on the flow of the pumped vapors, the input area of the filter must be several times larger than the area of the inlet of the vacuum pipe.

After drying:

a) the dried product is discharged, canned or packaged (stage d),

b) after the defrost condensate desublimator 3 (stage e) water is formed biologically active composition, which is then subjected to a final filtering and bottling in sterile container.

C) melt atmospheric moisture is discharged into sewage communication.

Table 2 summarizes the data in stages reflecting the introduced changes and amendments.

Claims

1. The method of obtaining water biologically active composition based on melt condensate formed in rproduct, b) cooling the shelves for products, cameras sublimator and desublimator with carrying out the condensation of atmospheric moisture on the evaporator of sublimator, download the frozen product in the chamber of sublimator, g) freeze-drying the product with simultaneous condensation of the vapor product on the evaporator desublimator; d) discharging the dried product with its subsequent preservation or packaging, e) defrosting evaporators of sublimator and desublimator obtaining melt condensation of atmospheric moisture and biologically active aqueous composition, W) drain condensates obtained.

2. The method according to p. 1, according to which before freezing carry out a preliminary preparation of the product by washing and subsequent complete removal of moisture.

3. The method according to any of paragraphs.1 and 2, according to which in the process of freezing of the product of stage (a) it is placed in a pan, served airtight lid.

4. The method according to any of paragraphs.1-3, in accordance with which the drying process at the stage (g) carry out the freezing melted when loading product and additional condensation of atmospheric moisture on the evaporator of sublimator.

5. The method according to any of paragraphs.1-4, in accordance with which the PR is the filter.

6. The method according to any of paragraphs.1-5, in accordance with which the drying process at the stage (g) to depressurization of sublimator include air cutoff.

7. The method according to any of paragraphs.1-6, according to which during defrost on the stage (f) inlet air desublimator produce through a filter - dehydrator.

8. The method according to any of paragraphs.1-7, in accordance with which the discharge of the condensate phase (W) is produced through various drain pipes.

9. The method according to p. 8, in accordance with which the drain water biologically active composition is carried out in sterile containers, and melt condensation of atmospheric moisture are used for technical purposes.

10. Water biologically active composition based melt condensate obtained from cells and tissues protein products, characterized by natural ultrafiltration, molecular structure similar to ice and superior absorbency, as well as the following organoleptic characteristics:

Taste 0-2 points

The smell of 0-2 points

Color 0 gradation

The turbidity of 0 mg/l

and the fact that she received in accordance with the method according to any of paragraphs.1-9.

11. Device for producing water biologically active compositions by p. 10 containing sublimator will evaporate Italy for condensation of biologically active aqueous composition, connected to the evaporators of the refrigeration unit, connected with the vacuum pipe vacuum unit and separated from each other fixtures to drain thawed condensates specified water composition and atmospheric moisture, these evaporators are connected with the possibility of alternate first and both evaporators.

12. Installation according to p. 11, characterized by the fact that both evaporators are connected through a temperature controlled valves, solenoids, and an adjustable valve, forming a distribution system with refrigerant.

13. Installation according to p. 11 or 12, characterized in that sublimator contains sublimation chamber with an airtight cover installed on the camera shelf product, placed in trays with lids, with shelves made with the possibility of heating the evaporator to condense atmospheric moisture, the filter vapor product, installed at the entrance to the vacuum pipe, a tray for collecting melt condensation of atmospheric moisture and a device for its plum.

14. Installation according to p. 13, characterized in that the cover trays made of stainless steel and equipped with seals, for example, of silicone rubber is struc-drain filter.

16. Installation according to any one of paragraphs.11-15, characterized in that desublimator contains desublimation chamber, an evaporator for condensing biologically active aqueous composition and a device for draining water biologically active composition.

17. Installation according to p. 16, characterized in that the evaporator for condensing biologically active water compositions in the form of cylinder with double walls, between which is placed a liquid shirt and the coil, and is equipped with a fairing mounted coaxially to the evaporator in the upper part.

18. Installation according to any one of paragraphs.16 and 17, characterized in that desublimator equipped with a surge tank for liquid shirt and a device to drain it.

19. Installation according to any one of paragraphs.11-17, characterized in that the vacuum pipe is equipped with air separation cutoff.

20. Installation according to p. 19, characterized in that it is equipped with sterilization and drying the filter, established on the site of the vacuum pipe between the air separation cutoff and the entrance to desublimator.



 

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