Condition-responsive control processes (C12Q3)

ethod for managing the process of photoavtotrophic microorganisms cultivation // 2622081
FIELD: biotechnology.SUBSTANCE: method for managing the process of photoautotrophic microorganisms cultivation is proposed. The method comprises feeding a suspension of a photoautotrophic microorganism to the photobioreactor, enriching the suspension with carbon dioxide, lighting the photobioreactor with an artificial light source, cooling the suspension during the cultivation with a cold coolant, removing the oxygen released as a result of cultivation, measuring the regulatory parameters of cultivation, and regulating them.EFFECT: increasing the efficiency of fotoautotrofic microorganisms cultivation, intensification of growth of cell suspensions, and increasing yield and quality of microorganisms biomass.1 dwg

Bioreactor for growing methane-recycling microorganisms // 2607782
FIELD: biochemistry.SUBSTANCE: invention relates to biochemistry. Disclosed is a bioreactor for growing methane-recycling microorganisms with possibility of using methane-containing gas and oxygen-containing gas as substrates for cell growth. Bioreactor is a vertical cylindrical housing with a cover, bottom and central circulation pipe. In upper part of housing of bioreactor on opposite sides there are two closed sectors. Closed sectors form an external reaction volume, each sector is equipped with pipes to feed gaseous substrate for discharge of gas-liquid dispersion medium and to feeding a liquid stream into lower part of sector. Discharge pipe is connected with central circulation pipe, liquid stream feed pipe is connected with pipe for extraction of culture liquid from bottom of bioreactor. In each closed sector there is a mixing device with a logical device.EFFECT: higher efficiency with simultaneous reduction of power consumption, as well as possibility of making a bioreactor in proposed design of different volume.13 cl, 1 dwg
ethod for producing bread kvass // 2593157
FIELD: food industry. SUBSTANCE: invention relates to production process for kvass beverage. Method envisages preparation of recipe components, extraction of plum jelly with liquid carbon dioxide to separate corresponding miscella, cutting oyster plant, drying it in microwave field till residual humidity about 20 % at microwave field power providing warming inside oyster plant bits to temperature of 80-90 °C during at least 1 hour, frying, impregnation with separated miscella under simultaneous pressure boost, pressure dropping to atmospheric value with simultaneous freezing of oyster plant, crushing and mashing together with kvass breads and hot water, and three-time maintenance with separation of liquid phase from thick to produce kvass wort, adding 25 % of recipe quantity of sugar in form of white syrup, fermentation with mixture of pure cultures of kvass yeast strain M and lactic acid bacteria strains 11 and 13, blending with remaining sugar in form of white syrup, and bottling. EFFECT: method reduces duration of process and increases foam stability of target product. 1 cl

Device and method for automated maintenance of concentration of dissolved gases in culture medium in microfluid system // 2587628
FIELD: biochemistry.SUBSTANCE: disclosed is a method for automatic maintenance of concentration of dissolved gases in a culture medium, located in cell with a cell model and circulating via microfluid system channels, and device for realising said method. Method is based on use of proportional-integral-differential control. Measured parameter used is concentration of oxygen and/or carbon dioxide in layer of gas-permeable material in a separate measurement cell. Specified parameter used is a parameter calculated from required parameter of gas concentration in cell with cell model based on coefficient of communication of concentrations in measurement and cellular cells.EFFECT: inventions provide absence of mutual negative influence of cell cultures and elements of device, longer service life of device, reliability of device with sufficiently high accuracy of maintaining concentration of dissolved gases and maintaining typically low for micro-fluid devices volume of liquid in channels.10 cl, 6 dwg

Port for feeding test chemical compound and withdrawal of fluid from cells for cultivation of cell models // 2583310
FIELD: biochemistry.SUBSTANCE: invention relates to structural elements of micro bioreactors. Disclosed is port for administration of tested chemical compound and withdrawal of fluid from cell for cultivation of cell models. Port is made of fixed and moving parts. Each part is equipped with two through holes, and fixed part is additionally equipped with extended slot on side of end surface. Fixed part has top and bottom parts. Lower part is made with possibility of its tight placement in cell, and upper part is made with recess for placement and fixation of movable part to turn latter relative to axis of valve in "open" and "closed" positions. In open position through holes in fixed and moving parts are combined to form two channels for insertion and withdrawal, and in closed position through holes of movable part are combined with extended slot to form channel for flushing of through holes.EFFECT: invention provides sterility in multiple input and fluid sampling and minimising mechanical effects on cells.14 cl, 2 dwg

Fermentation apparatus for methane-assimilating microorganisms // 2580646
FIELD: biochemistry.SUBSTANCE: invention relates to the field of biochemistry. Disclosed is a fermentation plant for methane-assimilating microorganisms. Plant comprises a column fermenter and two reactors. Fermenter comprises a housing, an exhaust gas outlet pipe, a tube for feeding nutrient salts, process water, food components and seed biosuspension, a pipe for inlet of gas-liquid flow into fermenter from reactor and a pipe for outlet of biosuspension from fermenter into reactor. Each reactor comprises a sampling tube for gas-liquid flow in fermenter, a disc mixer with a drive, a pipe for feeding biosuspension from fermenter into reactor. First reactor comprises a pipe for feeding methane-containing gas, second reactor comprises a pipe for feeding oxygen-containing gas. Fermenter additionally contains temperature maintenance means, means of maintaining pH of medium, means of maintaining level of dissolved oxygen, exhaust gas analyser. Mixer drive in each reactor is equipped with power transducer connected via logical device controller with flow rate regulators of incoming gas flows and with control valves of supply of liquid in each reactor.EFFECT: invention reduces power consumption on process of aerobic fermentation, high degree of usage of oxygen and methane, increased efficiency, as well as possibility of making efficient industrial plants with volume of up to 100-400 m3.12 cl, 1 dwg

ethod of production of biomass of photoautotrophic microorganisms // 2577150
FIELD: biotechnologies.SUBSTANCE: method of production of a biomass of photoautotrophic microorganisms is offered. The method includes the preparation of liquid inoculum in an inoculator at continuous lighting and aeration by carbon dioxide with the subsequent supply of the obtained culture into the fermenter. Cultivation of the biomass in the fermenter is performed with the film-size flow of liquid in transparent tubes with simultaneous lighting by a lamp and aeration by carbon dioxide and supply of the ready culture of microorganisms into the ready culture collector. From the collector the biomass is supplied to the spray dryer where it is dried by warm air and the ready-made product is obtained in a powdery form with the content of solids of 95…97%.EFFECT: increase of the yield of the biomass, decrease of specific energy consumption, ensuring ecological safety, improvement of quality and increase of periods of storage of the finished product.1 dwg

System for control of photosynthetic and respiratory co2-gas exchange of plants, isolated organs and tissues in vitro // 2572349
FIELD: chemistry.SUBSTANCE: claimed is system for control of photosynthetic ad respiratory CO2-gas exchange in culture in vitro. System is connected in hermetic way via standard sealant with transparent technological volume in vitro with cultivated whole plants at different stages of ontogenesis, regenerants, isolated organs and tissues. System together with connected technological volume forms common hermetic air contour. Contour consists of successively connected with each other said technological volume and air pump, rotameter, air drier and CO2-gas-analyser. Contour between CO2-gas-analyser and technological volume in vitro is additionally equipped with on-off gas switch.EFFECT: invention provides multiple reproducibility of measurement procedure.2 cl, 3 dwg, 1 tbl

ethod of producing biogas and apparatus therefor // 2561461
FIELD: chemistry.SUBSTANCE: group of inventions relates to biochemistry. A method and an apparatus for producing biogas from organic substances are disclosed. The method includes feeding a substrate into a container with a mixing mechanism, measuring rheological properties of the fermentation substrate in the region near impellers of the mixing mechanism. The measurement result is compared with a given value which is the desired value for a specific apparatus. The apparatus for producing biogas from organic substances comprises a container, a feeding system, a mixing mechanism, a sensor for measuring rheological properties of the fermentation substrate and a control unit.EFFECT: larger amount of the converted fermentation substrate and the generated amount of methane gas.18 cl, 2 dwg

ethod and apparatus for producing biogas // 2561460
FIELD: chemistry.SUBSTANCE: group of inventions relates to biochemistry. A method and an apparatus for producing biogas from organic substances are disclosed. The method includes feeding a substrate into a container with two mixing mechanisms with impellers. A common area is created in the container for mixing the fermentation substrate. The average speed of the fermentation substrate and/or average viscosity of the fermentation substrate in the mixing area are determined. The measurement data are sent to a control unit and controlled quantitative values are varied by the control unit. The apparatus comprises a container, a feeding system, a sensor for monitoring the process and mixing mechanisms, a control unit and mixing mechanisms with impellers. The impellers enable to generate horizontal streams of the contents of the container.EFFECT: larger amount of the converted fermentation substrate and the generated amount of methane gas.20 cl, 3 dwg

Bioreactor and method of culturing photosynthesising microorganisms using said bioreactor // 2471863
FIELD: chemistry.SUBSTANCE: bioreactor has a vessel (1) with a cover (2) and a device for mixing and aerating microorganisms, having pipes (3 and 4) on the cover for inlet of aerating gas and outlet of gaseous medium, respectively. The vessel (1) is fitted with multiple coaxially arranged and spaced apart annular partitions (12 and 13) with floats (14 and 15) which are open at the bottom, on a vertical hollow shaft (11) with possibility of rotation and back-and-forth movement thereon with formation of a gap between the wall of the vessel (1) and the annular partitions (12 and 13). The vessel (1) and the cover (2) of the reactor are made from transparent materials. The bioreactor has a meant (19) of holding the reactor afloat in a liquid medium and sources (20 and 21) of artificial light, which are mounted inside the floats (14 and 15) of the annular partitions (12 and 13). The latter are made from optically transparent material. The vessel is in form of a disposable or reusable dismountable envelope (22) and has means (23 and 24) of fastening it to the cover (2) and the bottom (17) of the vessel, respectively. The method of culturing photosynthesising microorganisms involves creating biochemical and physical conditions for growth of the microorganisms in a culture medium and maintaining culturing temperature conditions. The latter is carried out in the bioreactor, which is immersed and held afloat in a natural or manmade water body at water temperature which is favourable for growth of photosynthesising microorganisms in said water body, wherein the culture medium used is the filtered water from the water body in which the bioreactor is located.EFFECT: high output of biomass of photosynthesising microorganisms, while reducing power consumption and simplifying maintenance.6 cl, 1 dwg

ethod for improving measurement accuracy of microorganism heat production in fermentation vessel // 2461632
FIELD: medicine.SUBSTANCE: method involves measuring heat production by variation of heat rate consumed by maintenance of the isothermal mode of a fermentation vessel with intermitted fluid and gas flows through the fermentation vessel with adjusted heat power consumption by mixing the culture fluid. It is combined with eliminating heat power consumption by heat production in the fermentation vessel of the culture fluid mass due to maintaining its initial value at the pre-set accuracy in the environment of the conducted continuous and periodic cultivation processes by equation of energy gain, consumed for each heating cycle of the fermentation vessel, the energy gain value derived by calibration heating of the fermentation vessel filled with the initial culture fluid mass with the heat production value and the maintenance of the culture fluid mass during the microorganism cultivation process are spread out over a period of time.EFFECT: increased measurement accuracy of continuous and periodic microorganism heat production in the fermentation vessel.2 cl, 3 dwg

ethod of control of photoautotrophic microorganism cultivation process // 2458147
FIELD: medicine.SUBSTANCE: initial nutrient medium together with an inoculated autotrophic microorganism is supplied from a technological container into an input section of a photobioreactor with forming a suspension film of a photoautotrophic microorganism flowing down by gravity on an internal surface of transparent cylindrical tubes. Simultaneously, mixed air and carbon dioxide are reverse-flow supplied inside the tubes with using sleeves with suspension film outflow. The photoautotrophic microorganism suspension flowing in the internal surface of the transparent cylindrical tubes gets into a light section wherein it is continuously illuminated with a fluorescent tube. From the transparent cylindrical tubes, the photoautotrophic microorganism suspension flows down in an output section of the photobioreactor wherein it is bubbled to saturate the cells with carbon dioxide additionally and illuminated with a horizontal toroidal lamp. An external surface of the transparent cylindrical tubes is sequentially cooled in cooling air in the light section and in cooling water in the cooling section with cooling air and cooling water flowing in the respective recirculation loops. The photoautotrophic microorganism suspension is added with a nutrient medium of main and correction flows supplied into a technological container at first and then into the suspension recirculation loop at the input of the input section of the photobioreactor. Waste mixed air and carbon dioxide are supplied from the photobioreactor into the mixer by means of a compressor through the mixed air and carbon dioxide recirculation loop and temporarily collected in a gas tank. Post-bubble foam is continuously discharged from a lower section of the photobioreactor into an anti-foaming separator and separated into a suspension supplied into the input section of the photobioreactor and mixed air and carbon dioxide combined with waste mixed air and carbon dioxide in a regulation loop, while being temporarily collected in the gas tank and supplied into the mixer with extra saturation of waste mixed air and carbon dioxide with a required amount of carbon dioxide. Carbon dioxide saturated mixed air and carbon dioxide are discharged from the mixed by two ducts one of which being a main flow is reverse-flow directed inside the transparent cylindrical tubes; the other one is supplied into the output portion of the photobioreactor when bubbling the suspension. From the output portion of the photobioreactor, the microorganism suspension is discharged from the suspension recirculation loop with intermediate vented out oxygen release accompanying a cultivation process with using a desorber; another portion of the photoautotrophic microorganism suspension is discharged in a finished biomass collector to be measured for the required values for the purpose of creating optimal conditions for photoautotrophic microorganism cultivation.EFFECT: invention provides higher effectiveness of photoautotrophic microorganism cultivation, enabled integration of the presented method into the current production lines, improved energy efficiency and performance of photoautotrophic microorganism cultivation.2 ex, 1 dwg

ethod of measuring heat production of microorganisms in fermentation vessel in continuous and periodic processes and fermentation apparatus for realising said method // 2391410
FIELD: chemistry; biochemistry.SUBSTANCE: proposed method can primarily be used in biotechnology, biochemistry and industrial microbiology. Fermentation apparatus are used to study growth and metabolism of microorganisms and for solving several other tasks. Proposed solution involves measurement within given time intervals of flow of liquid and gaseous media through a fermentation vessel at the beginning of the fermentation process and during the said process after selected time intervals necessary for measuring heat production of microorganisms and evaluating destabilising inputs of heat power from operation of apparatus for moving the culture fluid. Heat production is calculated as the increment of current values of heat power to the initial value of the measured heat power while making corrections for the effect of the said destabilising inputs. The method is realised in a fermentation apparatus in which a fermentation vessel is placed inside a controlled thermostating screen and is fitted with an additional mixing device for controlling temperature of the fermentation vessel. Pipes running to the fermentation vessel are in thermal contact with the controlled thermostating screen.EFFECT: more accurate measurement of heat production of microorganisms in a fermentation vessel in continuous or periodic processes.4 cl, 5 dwg, 1 tbl
ethod of automatically governing biotechnological process // 2248399
FIELD: biotechnology and microbiological industry.SUBSTANCE: invention concerns governing periodical air-intake biotechnological process carried out in bioreactor. Method comprises measuring oxygen content in effluent gas, working volume of culture medium, concentration of biomass, and concentration of intermediate product of its vital activity. Measured parameters allow specific oxygen consumption rate and velocity of intermediate product concentration change to be determined to enable regulation of feeding air used in aeration, supplying nutritional medium, and agitating culture medium. Moreover, temperature of culture medium, temperature of supplied and withdrawn cooling agent, and consumption of the latter are measured to use these parameters for determining biomass heat release rate and velocity of intermediate product amount change. The two latter parameters enable regulation of feeding air used in aeration and supplying nutritional medium. The following characteristics are thus improved: elevating power by 8.1%, maltase activity by 7.9% and resistance by 7.4%.EFFECT: enhanced efficiency of governing biotechnological process and improved qualitative characteristics of process.2 ex

The method of growing baker's yeast // 2230111
The invention relates to the microbiological industry, and specifically to the production of Baker's yeast

ethod of monitoring microbiological process in the fluid flow (options) // 2192474
The invention relates to pharmaceutical and biotechnological production, and can also be used in wastewater treatment, production using fermentation and fermentation

The method of automatic control of the process of growing microorganisms // 2171843
The invention relates to the microbiological industry, and in particular to methods of automatic control of the process of growing microorganisms

Automatic process control aeration during the fermentation of organic raw materials // 2136760
The invention relates to the microbiological industry, and can be used in agriculture to control the fermentation process of organic raw materials

The method of automatic control of the process of growing microorganisms // 2132881
The invention relates to the microbiological industry, and in particular to methods of automatic control of the process of growing microorganisms, and can be used in the production of bakery yeast
The method for determining the number of microorganisms in deionized water // 2036239
The invention relates to microbiological control and can be used in microelectronics, bio - and medical technologies for the control of bacteria in ultrapure water

The method of measuring the rate of photosynthesis of microalgae in photoreactor and device for its implementation // 2021375
The invention relates to the measurement techniques used in the measurement of the intensity of photosynthesis of microalgae in industrial and laboratory conditions

The method of cultivation of photosynthetic microorganisms and installation for its implementation // 2019565
The invention relates to methods and facilities managed cultivation of photosynthetic microorganisms that can be used in agriculture and microbiological industry

The method of cultivation of photosynthetic microorganisms and installation for its implementation // 2019564
The invention relates to methods and facilities managed cultivation of photosynthetic microorganisms that can be used in agriculture and microbiological industry

A method of processing sample cell suspension electric current for genetic studies and device for its implementation // 2005776
The invention relates to biotechnology and can be used for the introduction of various biological molecules/sec
 
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