(C07C51/367)

ethod for alcoxyphenol and alcoxyhydroxybenzaldehyde production // 2628525
FIELD: chemistry.SUBSTANCE: method for alkoxyphenol production comprises O-alkylation of at least one hydroxyphenol to form at least one alkoxyphenol, at that, the said reaction is carried out using an O-alkylating agent, an aqueous solvent containing a Bronsted base and an organic solvent with a base/O-alkylating agent ration in the range of 0.5 to 1.5 moles of base per mole of O-alkylating agent, with an O-alkylating agent/hydroxyphenol ratio in the range of 0.5 to 2 moles of O-alkylating agent per mole of hydroxyphenol and with an organic solvent/hydroxyphenol ratio of less than 280 ml, preferably in the range of 10 to 250 ml and more preferably in the range of 50 to 150 ml of an organic solvent per mole of hydroxyphenol. One of the versions of the alkoxyhydroxybenzaldehyde production method comprises preparation of alkoxyphenol from hydroxyphenol by the foregoing method and a reaction of the aldehyde group addition to the resulting alkoxyphenol to obtain the corresponding alkoxyhydroxybenzaldehyde, preferably by condensation reaction between alkoxyphenol and glyoxylic acid, followed by oxidation of the resulting compound.EFFECT: proposed method for alkoxyphenol production allows the desired product to be obtained in good yield and high purity with high conversion of initial hydroxyphenol.11 cl, 3 dwg, 7 ex
ethod for producing alkyl salicylic acid // 2627768
FIELD: chemistry.SUBSTANCE: method for producing alkyl salicylic acid involves alkylation by the reaction of a long chainα-olefin and salicylic acid in a molar ratio of 1:1.05 to 1:1.14 in the presence of a heterogeneous sulphocathionite catalyst having a BET specific surface area of not more than 24 m2/g and not less than 22 m2/g.EFFECT: simplification of the method and increased output of the target product.3 cl, 2 tbl, 2 ex
2-[4'-(2",6"-dimethylphenoxy)benzoyl]benzoic acid and the method of preparation of the invention // 2621343
FIELD: chemistry.SUBSTANCE: invention relates to 2-[4'-(2",6"-dimethylphenoxy)benzoyl]benzoic acid which can be used as a by-product in the synthesis of polyarylene phthalides with valuable properties. A method for preparing acid I in 77% yield from 2-(4'-fluorobenzoyl) benzoic acid and 2.6-dimethylphenol in the presence of K2CO3 with two-stage heating: first in a mixture of N,N-dimethylacetamide with chlorobenzene until the azeotropic distillation of water and chlorobenzene is completed, then only in N,N-dimethylacetamide.EFFECT: increased quality of output.3 cl, 3 ex

ethod of producing 2-bromo-4,5-dialkoxybenzoic acid // 2576520
FIELD: chemistry.SUBSTANCE: method of producing 2-bromo-4,5-dialkoxybenzoic acid represented by the following formula , where each of R1 and R2 is a lower alkyl group, includes reacting 3,4-dialkoxybenzoic acid, represented by the following formula , where R1 and R2 have the same values as defined above, with bromine in a concentrated hydrochloric acid, where the reaction is carried out at 10-45°C. The method of producing 4,5-dialkoxy-2-hydrobenzoic acid, represented by the following formula , where each of R1 and R2 is a lower alkyl group, includes reacting 3,4-dialkoxybenzoic acid, represented by the following formula (1), where R1 and R2 have the same values as defined above, with bromine in a concentrated hydrochloric acid, where the reaction is carried out at 10-45°C; and the hydrolysis of the obtained 2-bromo-4,5-dialkoxybenzoic acid, represented by the following formula (2), where R1 and R2 have the same values as defined above, in the presence of a copper compound or an amine compound.EFFECT: high efficiency.11 cl, 3 tbl, 3 ex

ethod of obtaining highly fluorinated carboxylic acids and their salts // 2544855
FIELD: chemistry.SUBSTANCE: invention relates to a method of obtaining highly fluorinated carboxylic acids and their salts, as well as substances-precursors, which includes an impact on a highly fluorinated olefin, which has the general formula (I): Rf-(O)n-(CF2)m-CF=CF2 of a formic acid derivative in accordance with the general formula (II): HCOR in the presence of a radical initiator to form a substance-precursor of carboxylic acid in the form of O-ethers, S-ethers or an amide adduct of the general formula (III): Rf-(O)n-(CF2)m-CFH-CF2-COO and, optionally, in case of an acid obtaining, hydrolysis of an adduct of formula (III) to form carboxylic acid or its salts with the general formula (IV): Rf-(O)n-(CF2)m-CFH-CF2-COO-M+, where in formulas (II) and (III) R represents a residue O-M+, S-M+, OR' or SR' or NR'R", where R' and R" are independent on each other linear or branched or cyclic aliphatic residues, which contain at least one carbon atom and which do not have an alpha-H-atom, where the alpha-H-atom represents a hydrogen atom, bond with a carbon atom, bound with O, S or N in groups OR', SR' or NR'R", and where in formulas (I), (III), (IV) Rf represents H, either a perfluorinated or fluorinated linear or branched alkyl residue which can contain one or several catenary oxygen atoms, and n constitutes 1 or 0, m represents a number from 0 to 6, and M+ represents a cation.EFFECT: method makes it possible to obtain target compounds with the high output.8 cl, 7 ex

Novel method of producing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid // 2414449
FIELD: chemistry.SUBSTANCE: invention relates to a novel method of producing 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid of formula (I) through a Suzuki reaction between 3-adamantyl-4-methoxyphenylcarboxylic acid of formula (II) and 6-bromo-2-naphthoic acid of formula (III), wherein the reaction between compounds (II) and (III) is carried out at temperature between 60 and 110°C for between 30 minutes and 24 hours in an inert gas atmosphere in the presence of a palladium catalyst and a base in a polar solvent, followed by treatment with an acid. The invention also relates to use of compounds of formulae (II) and (III) to produce a compound of formula (I).EFFECT: single-step method enables to obtain desired product with high output.13 cl, 2 dwg, 3 ex

ethod of producing oxyethylated alkylphenol-based anionic surfactants // 2406719
FIELD: chemistry.SUBSTANCE: invention relates to production of anionic surfactants, specifically to methods of producing carboxymethylates of oxyethylated alkylphenols used as components of detergents for domestic and industrial purposes - intensification of oil extraction processes by increasing ratio of extraction of oil from oil deposits. The method of producing oxyethylated alkylphenol-based anionic surfactants is realised through condensation of oxyethylated alkylphenols with sodium monochloroacetate in molar ratio 1.0:(0.8-1.0) in nitrogen medium while heating in the presence of an alkaline agent at 45-50°C. The alkaline agent used is crystalline potassium hydroxide taken in molar ratio to the oxyethylated alkylphenol equal to (0.7-1.0):1.0 or its mixture with crystalline sodium hydroxide in the same molar ratio to the oxyethylated alkylphenol. After condensation, a hydrogen ion concentration (pH) regulator is added to the reaction mixture in molar ratio of pH regulator to the oxyethylated alkylphenol equal to (0.01-0.1):1.0 until attaining pH of the reaction mixture of 8.0-9.0. The anionic surfactant is stored without partial decomposition and resin formation for not less than 100 days.EFFECT: efficient method of producing anionic surfactants.4 cl, 1 tbl, 15 ex

Synthesis of oxygen-substituted benzocycloheptenes as valuable intermediate compounds for preparing tissue-selective estrogens // 2310643
FIELD: organic chemistry, chemical technology.SUBSTANCE: invention relates to novel intermediate compounds and inmproved method for synthesis of compound of the formula (C): . Proposed method is based on using inexpensive parent substances and provides synthesis of intermediate compounds with the high yield and high purity degree being without carrying out procedures for chromatographic purification and can be realized in large-scale industry manufacture. Invention relates to improved methods for synthesis of compound of the formula (I): , compound of the formula (II): , compound of the formula (III): , compound of the formula (VIII): , compound of the formula (IX): , and to a reagent consisting of boron tribromide and 2,6-dimethylpyridine. Method is used for a sparing and selective splitting a methyl group in aromatic methyl ethers.EFFECT: improved method of synthesis.12 cl, 8 ex

A method of obtaining a possibly substituted p-hydroxymandelic connections // 2232746
The invention relates to an improved method for producing a p-hydroxymandelic compounds by condensation in the water, in the presence of an alkaline agent, an aromatic compound containing at least one hydroxyl group and having a free parapolitica, with Glyoxylic acid
 
2551228.
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