Polycyclic (C07C47/57)

ethod for alcoxyphenol and alcoxyhydroxybenzaldehyde production // 2628525
FIELD: chemistry.SUBSTANCE: method for alkoxyphenol production comprises O-alkylation of at least one hydroxyphenol to form at least one alkoxyphenol, at that, the said reaction is carried out using an O-alkylating agent, an aqueous solvent containing a Bronsted base and an organic solvent with a base/O-alkylating agent ration in the range of 0.5 to 1.5 moles of base per mole of O-alkylating agent, with an O-alkylating agent/hydroxyphenol ratio in the range of 0.5 to 2 moles of O-alkylating agent per mole of hydroxyphenol and with an organic solvent/hydroxyphenol ratio of less than 280 ml, preferably in the range of 10 to 250 ml and more preferably in the range of 50 to 150 ml of an organic solvent per mole of hydroxyphenol. One of the versions of the alkoxyhydroxybenzaldehyde production method comprises preparation of alkoxyphenol from hydroxyphenol by the foregoing method and a reaction of the aldehyde group addition to the resulting alkoxyphenol to obtain the corresponding alkoxyhydroxybenzaldehyde, preferably by condensation reaction between alkoxyphenol and glyoxylic acid, followed by oxidation of the resulting compound.EFFECT: proposed method for alkoxyphenol production allows the desired product to be obtained in good yield and high purity with high conversion of initial hydroxyphenol.11 cl, 3 dwg, 7 ex

2,6-diisobornyl phenol derivatives // 2575294
FIELD: chemistry.SUBSTANCE: invention relates to the novel sterically hindered phenols which are intermediate compounds for the further functionalisation of 2,6-diisobornyl phenol,, where the isobornyl fragments have the configuration (1S, 2R, 4R, 1'R, 2'S, 4'S), where the isobornyl fragments have the configuration (1S, 2R, 4R, 1'S, 2'R, 4'R) and (1R, 2S, 4S 1'R, 2'S, 4'S), R1 is a formyl group or a group of general formula II -(CH2)nNX2, where X is a C1-C8 alkyl radical, straight or branched, cyclohexyl-, morpholine-, piperidine-, benzyl-, salsolidine, salsoline, N-benzyl-1-phenylethylamine, n=1-10.EFFECT: high output.2 cl, 2 ex
ethod of producing 3-chloromethyl-4-methoxybenzaldehyde // 2561730
FIELD: chemistry.SUBSTANCE: method includes chloromethylation of 4-methoxybenzaldehyde with formaldehyde, which is used in the form of paraform, the reaction being carried out in the presence of concentrated hydrochloric acid at 70-75C while stirring. A reaction mixture is fed into the chloromethylation reaction, wherein the ratio of formaldehyde to 4-methoxybenzaldehyde in the reaction mixture is equal to 1.1-1.8:1. The reaction mass is then heated and stirred for 2.5-3.5 hours, followed by cooling to temperature of -5C to -10C. The precipitate is filtered out, dried on air and recrystallised from hexane.EFFECT: method enables to obtain a pure end product with high output using a simple and safe technique.4 ex

5-[1'-(decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1h-cyclopropa[a]naphthalen-4-yl)-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde as medicinal agents // 2453527
FIELD: chemistry.SUBSTANCE: invention relates to a pharmaceutical composition containing primary material in form of at least one compound selected from 5-[(1'R)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde and 5-[(1'S)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde, in a combination with an acceptable carrier, for treating and/or preventing disorders or pathologies which are a result of a disorder of reuptake of the following neuromediators: dopamine, serotonin and/or noradrenaline, as well as to use of at least one compound selected from 5-[(1'R)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde and 5-[(1'S)-1'-[(1aS,3aS,4S,7R,7aR,7bS)-decahydro-7-hydroxy-1,1,3a,7-tetramethyl-1H-cyclopropa[A]naphthalen-4-yl]-3'-methylbutyl]-2,4,6-trihydroxy-1,3-benzene dicarboxaldehyde to obtain a medicinal agent.EFFECT: improved method.9 cl, 2 ex, 1 tbl

6-(polysubstituted aryl)-4-aminopicolinates and use thereof as herbicides // 2428416
FIELD: chemistry.SUBSTANCE: invention relates to a compound of formula used as herbicides, in which Q1 is H or F; Q2 is a halogen provided that when Q1 is H, Q2 is Cl or Br; R1 and R2 independently denote H, C1-C6-acyl; and Ar is a polysubstituted aryl group selected from a group consisting of a) , b) , c) in which W1 is a halogen; X1 is C1-C4-alkyl, C1-C4-alkoxy, C1-C4-halogenalkyl, -NR3R4; Y1 is C1-C4-alkyl, C1-C4-halogenalkyl, halogen or -CN, or when X1 and Y1 are taken together denotes -O(CH2)nO-, in which n=1; and R3 and R4 independently denote H or C1-C4-alkyl; W2 is F or Cl; X2 is F, CI, -CN, C1-C4-alkyl, C1-C4-alkoxy, C1-C4-alkylthio, C1-C4-alkylthionyl, C1-C4-alkylsulphonyl, C1-C4-halogenalkyl, C1-C4-halogenalkoxy, C1-C4-alkoxy-substituted C1-C4-alkyl, C1-C4-alkoxy-substituted C1-C4-alkoxy, -NR3R4 or fluorinated acetyl; Y2 is a halogen, C1-C4-alkyl, C1-C4-halogenalkyl or -CN, or when W2 is F, Xz and Y2, taken together, denote -O(CH2)nO-, in which n=1; and R3 and R4 independently denote H or C1-C6-alkyl; Y3 is a halogen or -CN; Z3 is F, CI, -NO2, C1-C4-alkoxy, -NR3R4; and R3 and R4 independently denote H; derivatives on the carboxyl group which are suitable for use in agriculture.EFFECT: compounds are excellent herbicides with a wide range action against weeds and excellent selectivity towards agricultural crops.19 cl, 7 tbl, 69 ex
ethod of extracting ortho-vanilin and iso-vanilin from aqueous solutions // 2422430
FIELD: chemistry.SUBSTANCE: invention relates to a method of extracting ortho-vanilin and iso-vanilin from aqueous solutions. The method involves addition of a salting-out agent - sodium chloride to aqueous solutions of ortho-vanilin and iso-vanilin and a solution of polyvinyl caprolactam prepared beforehand, having concentration of 5-15 wt % until achieving 34-35 wt % content of salt in the solution, with volume ratio of the aqueous phase to organic phase equal to 10:1. The organic phase is extracted and separated, analysed spectrophotometrically and the recovery ratio (R, %) of ortho-vanilin and iso-vanilin is calculated using the formula: R=D100/(D+r), where D is coefficient of distribution of ortho-vanilin and iso-vanilin between the solution of polyvinyl caprolactam and the aqueous solution, r is the ratio of equilibrium volumes of the aqueous and organic phases.EFFECT: method increases recovery ratio of ortho-vanilin and iso-vanilin from aqueous solutions.1 tbl, 2 ex
ethod of extracting vanilin, ethylvanilin, isovanilin and orto-vanilin from water solutions // 2352553
FIELD: chemistry.SUBSTANCE: method of extracting vanillin, ethylvanillin, iso-vanillin and ortho-vanillin from water solutions is characterised by the following: preliminarily to water solutions of vanillin, ethylvanillin, iso-vanillin and ortho-vanillin added are; ammonium sulphate, until its content in solution is 42-43% to solution weight, and preliminary prepared mixture of solvents, consisting of 22-23 wt % acetone and 78-77 wt % diacetone alcohol, then extraction is carried out with molar ratio of water and organic phases 10:1, and degree of vanillins extraction (R,%) is calculated by formula: R=D-100/(D+r), where D is coefficient of vanillins distribution between solvent mixture and water-salt solution, r is ratio of equiweight volumes of water and organic phases.EFFECT: increase of degree of vanillin, ethylvanillin, iso-vanillin and ortho-vanillin extraction from water solutions.1 tbl, 2 ex
ethod of vanillin and lilac aldehyde extraction // 2348606
FIELD: chemistry.SUBSTANCE: vanillin is applied in confectionery, pharmaceutics and manufacturing of perfume and cosmetics, and lilac aldehyde is applied in manufacturing of trimetoprim, biseptol and other pharmaceutical drugs. Method involves extraction by oxygen-containing extraction agents at pH 6.0-8.0 and re-extraction by water alkaline solution at pH 10-14. Extraction stage involves use of tributhylphosphate, or kerosene solutions of tributylphosphate with 40-99 wt % of tributylphosphate, as extraction agents.EFFECT: reduced volume of extraction agent required at extraction stage in comparison to existing technique.7 ex

The method of obtaining 2,3,4-trimethoxybenzaldehyde // 2236397
The invention relates to an improved process for the preparation of 2,3,4-trimethoxybenzaldehyde, which is used as an intermediate product to obtain drug - Trimetazidine

The method of obtaining 2,3,4-trimethoxybenzaldehyde // 2234492
The invention relates to an improved process for the preparation of 2,3,4-trimethoxybenzaldehyde used as an intermediate product for the synthesis of medicinal substances
The method of processing wood small-leaved species into valuable organic products // 2219048
The invention relates to a method for products of fine organic synthesis of vanilla, lilac aldehyde, levulinate acid

The method of obtaining 4-hydroxybenzaldehyde and its derivatives // 2194032
The invention relates to a new method of obtaining 4-hydroxybenzaldehyde and its derivatives, in particular for the preparation of 3-methoxy-4-hydroxybenzaldehyde (vanilla) and 3-ethoxy-4-hydroxybenzaldehyde (ethylvanillin)
The method of selection of vanilla and lilac aldehyde // 2177935
The invention relates to the field of fine organic synthesis, namely the method of selection of vanilla and lilac aldehyde from a solution obtained by oxidation lignindegrading raw materials by extraction of the high-boiling alcohols or esters having a boiling point of more than 130oSince at pH 6-8 with further reextracting aqueous-alkaline solution at pH 10 to 14 and the release of vanillin by acidification with sulfuric acid to pH 5

Afterperiod or their pharmaceutically acceptable salts, method of production thereof, pharmaceutical compositions on their basis and intermediate substances // 2167849
The invention relates to new naphtylpropionate F.-ly (I), where R1and R2- N, -HE or-O(C1-C4-alkyl); R3- 1-piperidinyl, 1-pyrrolidinyl, methyl-1-pyrrolidinyl, dimethyl-1-pyrrolidinyl, 4-morpholinyl, dialkylamino - or 1-hexamethylen-aminogroup; n = 2 or 3, or pharmaceutically acceptable salts

ethod for preparation of aromatic aldehydes // 2165920
The invention relates to a thin organic synthesis, specifically to a technology for aromatic aldehydes

ethod for preparation of aromatic aldehydes from lignostone raw materials // 2164511
The invention relates to a thin organic synthesis, specifically to a technology for aromatic aldehydes from lignostone raw materials

The method of chemical processing of wood // 2158192
The invention relates to the field of fine organic synthesis, particularly to a technology of obtaining vanillin, levulinate acid and 5-oxymethylphenyl wood
The method of processing wood into products of fine organic synthesis // 2119427
The invention relates to the field of fine organic synthesis, specifically to a technology for vanilla, lilac aldehyde, levulinate acid from wood
 
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