Compounds having and cho groups (C07C47)

C07C47/04 - Formaldehyde(93)
C07C47/042 - With a six-membered ring(1)
C07C47/048 - (22)
C07C47/055 - Containing halogen(14)
C07C47/058 - Vanillin(21)
C07C47/06 - Acetaldehyde(40)
C07C47/07 - Preparation by oxidation(18)
C07C47/11 - onocyclic(8)
C07C47/115 - (3)
C07C47/127 - (15)
C07C47/133 - (2)
C07C47/14 - Containing halogen(18)
C07C47/16 - Trichloroacetaldehyde(19)
C07C47/17 - Containing rings(1)
C07C47/19 - Containing hydroxy groups(23)
C07C47/222 - (1)
C07C47/225 - (6)
C07C47/228 - (7)
C07C47/23 - Polycyclic(4)
C07C47/232 - (2)
C07C47/238 - (2)
C07C47/24 - Containing halogen(8)
C07C47/26 - Containing hydroxy groups(3)
C07C47/263 - (1)
C07C47/30 - With a five-membered ring(1)
C07C47/32 - With a six-membered ring(1)
C07C47/34 - Polycyclic(4)
C07C47/347 - (1)
C07C47/36 - Containing hydroxy groups(1)
C07C47/42 - With a six-membered ring(4)
C07C47/44 - Polycyclic(2)
C07C47/453 - (1)
C07C47/54 - Benzaldehyde(43)
C07C47/542 - (5)
C07C47/544 - (4)
C07C47/546 - (7)
C07C47/55 - Containing halogen(6)
C07C47/56 - Containing hydroxy groups(42)
C07C47/565 - (10)
C07C47/57 - Polycyclic(37)
C07C47/58 - Vanillin(73)

ethod for alcoxyphenol and alcoxyhydroxybenzaldehyde production // 2628525
FIELD: chemistry.SUBSTANCE: method for alkoxyphenol production comprises O-alkylation of at least one hydroxyphenol to form at least one alkoxyphenol, at that, the said reaction is carried out using an O-alkylating agent, an aqueous solvent containing a Bronsted base and an organic solvent with a base/O-alkylating agent ration in the range of 0.5 to 1.5 moles of base per mole of O-alkylating agent, with an O-alkylating agent/hydroxyphenol ratio in the range of 0.5 to 2 moles of O-alkylating agent per mole of hydroxyphenol and with an organic solvent/hydroxyphenol ratio of less than 280 ml, preferably in the range of 10 to 250 ml and more preferably in the range of 50 to 150 ml of an organic solvent per mole of hydroxyphenol. One of the versions of the alkoxyhydroxybenzaldehyde production method comprises preparation of alkoxyphenol from hydroxyphenol by the foregoing method and a reaction of the aldehyde group addition to the resulting alkoxyphenol to obtain the corresponding alkoxyhydroxybenzaldehyde, preferably by condensation reaction between alkoxyphenol and glyoxylic acid, followed by oxidation of the resulting compound.EFFECT: proposed method for alkoxyphenol production allows the desired product to be obtained in good yield and high purity with high conversion of initial hydroxyphenol.11 cl, 3 dwg, 7 ex

ethod for selective hydrogenation of unsaturated aldehydes // 2626958
FIELD: chemistry.SUBSTANCE: invention relates to a method for producing saturated aldehydes by contacting a liquid organic feed containing unsaturated aldehydes with hydrogen or hydrogen-containing gas in presence of crustal catalyst comprising palladium particles of not more than 6 nm in size, applied in form of a layer not thicker than 150 microns on exterior surface of porous alumina carrier granules. Herewith the carrier has not less than 60% of pores with a diameter of 5 to 50 nm, and the hydrogenation is carried out at a liquid feed rate of 1-4 h-1.EFFECT: producing target products with high selectivity at high process efficiency and feedstock conversion.25 cl, 8 dwg, 6 tbl, 6 ex
ethod of obtaining an unsaturated aldehyde and/or unsaturated carboxylic acid // 2621715
FIELD: chemistry.SUBSTANCE: invention relates to an improved method of receipt of acrolein and acrylic acid or methacrolein and methacrylic acid, which effect on propylene or, at least, on one type of compounds selected from the group consisting of isobutylene tertiary butanol, as has a contact oxidation using gas containing molecular oxygen, using a fixed bed multitube reactor, where (A) provide many layers of catalyst formed by division of catalyst layer in layer N (N is an integer equal to or greater than 2) in the direction of flow of gaseous source materials in reaction tubes. And among segments of the catalyst layer of catalyst, which is located on the near side of the input reactive gas is defined as Zin, while catalyst layer located at the farthest outlet side reactive gas is defined as Zout, and (B) catalyst downloaded so that load into catalyst activity Zout, higher than loaded catalyst activity in Zin, and thus that is satisfied by the following equation (1): 0.5≤ (Cmax-Ccrs) (1), where Cmax is the degree of transformation of source materials in which the desired output product becomes maximum; Ccrs and represents the degree of transformation of raw materials where high/low ratio between the Tin and Tout changes to reverse when the maximum temperature layer of the catalyst Zin is defined as Tin, and the maximum temperature of the catalyst bed Zout is defined as Tout, and the conversion of the starting materials varies.EFFECT: method enables stable work process over an extended period of time.9 cl, 7 ex
Two-step process of obtaining the propionic aldehyde // 2619951
FIELD: chemistry.SUBSTANCE: method includes the step of hydroformylating ethylene with carbon monoxide at elevated temperature and pressure in the presence of a metal rhodium catalyst on a carrier. Prior to the hydroformylation step, a hydrogenation stage of carbon dioxide in the synthesis gas is preliminarily carried out in the presence of a catalyst containing metallic cobalt on a carrier in the form of an organometallic MIL-53 (Al) frame structure obtained in the course of microwave activated synthesis, and the process for producing propionaldehyde is carried out in flow two-way reactor at a pressure of 20-40 atm by contacting a stationary catalyst bed located on the upper shelf of the reactor and heated to a temperature of 500°C, with feed mixture H2 and CO2 at a gas feed rate of 500-1000 h-1 followed by mixing of the formed and heated to a temperature of 500-520°C of reaction gases containing a mixture of CO-H2-CO2, with cold ethylene, fed into the inter-bed space, and the resulting gas mixture at a ratio of CO:H2:C2H4=1:(1÷2):1 is fed to the lower shelf of the reactor and contacted at a temperature of 170-230°C with a hydroformylation catalyst present therein, presented by rhodium in the form of the organometallic framework structure MIL-53 (Al), obtained during autogenous hydrothermal synthesis.EFFECT: method allows to increase the selectivity of the formation of the target product, and the yield, ensuring the utilisation of greenhouse gas.3 cl, 2 dwg, 1 tbl, 8 ex

Oxide catalyst and method of producing thereof, as well as methods of producing unsaturated aldehyde, diolefin and unsaturated nitrile // 2615762
FIELD: chemistry.SUBSTANCE: oxide catalyst has the following characteristics: (1) the oxide catalyst comprises molybdenum, bismuth, iron, cobalt and element A which ionic radius is larger than 0.96 Å (except for potassium, cesium and rubidium); (2) the atomic ratio of a bismuth to 12 atoms of molybdenum 1≤a≤5 the atomic ratio of b iron to 12 atoms of molybdenum is 1,5≤b≤6, the atomic ratio of the c element A to 12 atoms of molybdenum is 1≤c≤5, and the atomic ratio of d cobalt to 12 atoms of molybdenum is 1≤d≤8; and (3) the oxide catalyst comprises a disordered phase, which consists of a crystal system which comprises molybdenum, bismuth, iron and the element A. Method of producing oxide catalyst, method of producing unsaturated aldehyde, method of producing diolefin and method of producing unsaturated nitrile are proposed as well.EFFECT: invention provides an oxide catalyst which prevents reductive decomposition of catalyst even during industrial operation for a long time.14 cl, 16 dwg, 11 tbl, 43 ex
ethod for producing 1-adamantyl acetaldehyde // 2612956
FIELD: chemistry.SUBSTANCE: present invention relates to the method of producing 1-adamantyl-acetaldehyde, used as a valuable intermediate product for synthesis of bioactive substances and functional organic materials. The method comprises a catalytic reaction between 1-adamantanol and vinyl acetate as an unsaturated compound. Vinyl acetate, 2.5-fold molar excess relative to 1-adamantanol; the reaction is caried out for 2 hours in dichloroethane at dichloroethane boiling point, indium tribromide is used as a catalyst, 5 mole %.EFFECT: target product produced using a simple process and readily available raw materials.2 tbl, 1 ex
ethod for producing acrylic acid from methanol and acetic acid // 2610431
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing acrylic acid from methanol and acetic acid, which involves following operations: through a first reaction zone A, which is loaded at least one oxidation catalyst A, passing a stream of reaction gas mixture A, containing reagents – methanol and molecular oxygen, as well as at least one inert gas diluent, different from water vapour, and when passing said reaction zone A methanol contained in supplied reaction gas mixture A, in conditions of heterogeneous catalysis is oxidised to formaldehyde and water vapour, so as to form a gaseous mixture of products A, containing formaldehyde, water vapour, at least one inert gas diluent, differing from water vapour, and optionally, excess molecular oxygen, and stream of gaseous mixture of products A exits reaction zone A, wherein to reaction gas mixture A passing through reaction zone A, on its path through reaction zone A can optionally be supplied additional molecular oxygen and/or additional inert gas diluent, optionally a stream of gaseous mixture of products A, leaving reaction zone A, is fed into separation zone T*, and in said separation zone T* from gaseous mixture of products A is optionally separated unreacted methanol still contained in gaseous mixture of products A, wherein remains gaseous mixture of products A*, containing formaldehyde, and a stream of gaseous mixture of products A* exits reaction zone A, from stream of gaseous mixture of products A or from stream of gaseous mixture of products A*, as well as at least one other stream of substances containing acetic acid, is obtained a stream of incoming reaction gas mixture B containing acetic acid, water vapour, at least one inert gas diluent, different from water vapour, formaldehyde and optionally molecular oxygen, in which is contained molar amount of acetic acid nHAc greater than molar amount of formaldehyde nFd contained therein, through second reaction zone B, in which is loaded at least one catalyst for aldol condensation B, is passed a stream of incoming reaction gas mixture B, and when passing said reaction zone B formaldehyde contained in supplied reaction gas mixture B, together with acetic acid contained in supplied reaction gas mixture B, under conditions of heterogeneous catalysis is condensed to acrylic acid and H2O, to form a gaseous mixture of products B containing acrylic acid, acetic acid, water vapour, at least one inert gas diluent, different from water vapour, and optionally molecular oxygen, and a stream of gaseous mixture of products B comes out of reaction zone B, wherein to reaction gas mixture B passing through reaction zone B, on its path through reaction zone B, may be supplied additional molecular oxygen and/or additional inert gas diluent, stream of gaseous mixture of products B, leaving reaction zone B is fed into separation zone T, and in said separation zone T is divided at least into three streams substances – X, Y and Z, wherein stream of acrylic acid contained in stream of substances X, is greater than stream of acrylic acid contained in streams of substances Y and Z, taken together, stream of acetic acid contained in stream of substances Y is greater than streams of acetic acid contained in streams of substances X and Z, taken together, stream of inert gas diluent, different from water vapour, contained in stream of substance Z, is greater than streams of inert gas diluent, different from water vapour contained in streams of substances X and Y taken together, and stream of substance Y is returned into reaction zone B and is additionally used for producing incoming reaction gas mixture B.EFFECT: disclosed is a method of producing acrylic acid from methanol and acetic acid.21 cl

Polymetallic oxide masses containing molybdenum, bismuth and iron // 2609023
FIELD: chemistry.SUBSTANCE: invention relates to polymetallic oxide mass, envelopment catalyst, solid catalytically active moulded article, production of polymetallic oxide mass, method for heterogeneous catalysed gas-phase partial oxidation of propylene to acrolein and acrylic acid. Polymetallic oxide mass as active mass for catalysis of heterogeneous catalysed gas-phase partial oxidation of propylene to acrolein and acrylic acid of general stoichiometric formula I, Mo12BiaCobFecKdSieOx (I) , where variables assume following values: a = from 0.5 to 1, b = from 7 to 8.5, c = from 1.5 to 3.0, d = from 0.04 to 0.15; e = from 0.5 to 2.5 and x is an integer defined by valence and elements other than oxygen in formula I, and following conditions are satisfied: condition 1: 12-b-1.5⋅c=A and 0.5 ≤ A ≤ 1.5; condition 2: 0.2 ≤ a/A ≤ 1.3 and condition 3: 3≤b/c≤9. Envelopment catalyst includes a moulded support article and located on outer surface of moulded support article shell, at least one polymetallic oxide mass as active mass. Method of producing polymetallic oxide mass involves creating, from sources of elementary components thereof, a fine dry mixture and calcining said mixture at temperatures within range of 350–650 °C. Method for heterogeneously catalysed gas-phase partial oxidation of propylene to acrolein and acrylic acid is carried out on catalyst bed, which contains polymetallic oxide mass.EFFECT: containing Mo, Bi and Fe polymetallic oxide mass as active mass of catalysts for gas-phase partial oxidation with heterogeneous catalysis of propylene to acrolein into main product and acrylic acid as a desirable by-product enable to improve overall selectivity of formation of acrolein and acrylic acid.12 cl, 6 dwg, 3 tbl

Improved method for hydroformylation // 2606629
FIELD: chemistry.SUBSTANCE: present invention relates to at least a two-step method of exothermic hydroformylation. Method includes following stages: (a) reacting hydroformylation reactants exothermically in a first reaction stage in a fluid reaction mixture to form a reaction product; (b) transferring a process stream of fluid reaction mixture from a reaction stage to one or more later and separate reaction stages for further exothermic, product-forming reaction and then to product recovery unit operations; (c) transferring a heat transfer stream of reaction mixture from a reaction stage to an external heat exchanger where it is cooled and dividing cooled stream into multiple cooled reaction mixture streams; (d) transferring a cooled reaction mixture stream from step (c) back into same reaction stage from which it was removed to cool reaction mixture in that reaction stage; (e) transferring at least one cooled reaction mixture stream from step (c) into and through heat exchange means that cool a different reaction stage, and returning it to same reaction stage from which it is removed; and (f) separating and recovering a reaction product from reaction mixture and optionally recycling at least some reaction mixture components to reaction mixture in a reaction stage.EFFECT: disclosed method enables to optimise control of process temperature and minimise pollution of reaction mixture due to cooling medium leakage.15 cl, 4 dwg, 1 ex

Reduced contamination during hydroformylation processes by adding water // 2601416
FIELD: chemistry.SUBSTANCE: present invention relates to a method of extracting for removal of metal salts from organic hydroformylation reaction fluid medium ("HRF") before the HRF return to the hydroformylation process reaction zone, herewith the HRF includes organophosphorus ligand and metal-complex organophosphorus ligand. Extraction method involves the step of the HRF contact with an aqueous buffer solution in the area of hydroformylation process buffer extraction, and the reaction zone is located upstream the buffer extraction zone. Herewith this method also includes the stage of the HRF contact with water ("added water") added in addition to the water present in the aqueous buffer solution performed (A) in the zone for extraction of salt, downstream the zone for extraction of buffer, and (B) before the HRF return to the reaction zone.EFFECT: proposed method allows to stabilize the organophosphorus ligand against hydrolytic dehydration, and the complex of metal-organophosphorus ligand - against degradation and deactivation.9 cl, 3 dwg, 3 tbl, 9 ex

Catalyst (versions), preparation method thereof and method of producing acetaldehyde // 2600452
FIELD: chemistry.SUBSTANCE: invention relates to catalysts (versions) for producing acetaldehyde in isomerisation of ethylene oxide, as well as to a method of preparing said catalysts. Active component of catalyst comprises zeolite of structure: MTT, TON, having composition: x Al2O3 - y El2O - SiO2, where x=0.1-5·10-2; y=2·10-3, El is at least one of elements of group 1 of periodic table, a compound which is used for hydrothermal synthesis of zeolite, or zeolite of same composition and structure subjected to thermo-steam treatment, selected from following: MFI, MEL, BEA, FER, MOR, FAU. Invention also relates to a method of producing acetaldehyde in isomerisation of ethylene oxide by passing steam-gas mixture of ethylene oxide with gas diluent, which can be nitrogen and/or any inert gas, and/or carbon dioxide, and/or air, and/or water vapour, through a layer of catalyst in presence of disclosed catalysts (versions).EFFECT: technical result is increasing conversion of ethylene oxide and selectivity on acetaldehyde, which provides high output of acetaldehyde.9 cl, 1 tbl, 36 ex

ethod of producing vanillin electrochemical oxidation of aqueous solutions or suspensions lignin // 2600322
FIELD: food industry.SUBSTANCE: invention relates to a method of vanillin producing. Method involves electrochemical oxidation of aqueous lignin-bearing suspension or solution on the anode, wherein a silver electrode is used as anode.EFFECT: using this invention enables to obtain vanillin with higher output and selectivity in conditions, facilitating less corrosion of electrodes, that enables to obtain less contaminated vanillin.15 cl, 10 ex, 1 tbl

ethod for continuous industrial production of glyoxal // 2599247
FIELD: technological processes.SUBSTANCE: present invention relates to a continuous method of producing glyoxal by oxidation of ethylene glycol with atmospheric oxygen in a mixture with recirculating inert gas on a catalyst containing silver. Recirculating gas used as a diluent and ethylene glycol solution entering reactor are successively pre-heated by heat generated during oxidation of ethylene glycol at catalyst, and cooling of reaction products is performed in successively by their irrigation with cooled solution of glyoxal in a zone lying immediately behind catalyst layer and in tubular sub-contact 2-sectional heat exchanger, in lower section of which ethylene glycol is heated, and in upper section - heating of recirculating gas used as a diluent.EFFECT: proposed method enables to obtain an end product with high output.7 cl, 3 dwg, 1 tbl, 3 ex

Improved method of oxosynthesis and method for production of synthesis gas from waste oils // 2598460
FIELD: technological processes.SUBSTANCE: invention relates to improved method for biosynthesis with recirculation of converted waste oils. Method involves hydroformylation of olefin with synthesis gas in reactor with obtaining of oxosynthesis product and by-products, oil wastes, characterized by lower or higher boiling point than product of oxosynthesis, separation of biosynthesis product of oil wastes, conversion of separated waste oils to synthetic gas, including evaporation of waste oils gaseous hydrocarbon in reservoir of evaporator to produce mixed steam gas flow of gaseous hydrocarbon and evaporated oil wastes and direct oxidation of mixed vapors gas flow to produce synthetic gas, and recirculation of synthesis gas.EFFECT: invention provides effective method of oxosynthesis with recirculation of converted waste oils and reduced soot formation.41 cl, 4 dwg, 1 tbl

ethod for preparation of 3,3-dimethylbutyraldehyde // 2591703
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing 3.3-dimethylbutyraldehyde, which is used as intermediate compound for producing of sweetener. Method consists in fact that with preliminary cooled dichloromethane one sequentially mixes in tank tert-butyl chloride and vinyl acetate to produce mixture which is held for catalytic reaction in presence of catalyst introduced into mixture, adding deionised water and stirring, after which organic phase is separated and washed with sodium carbonate solution, and then separated from dichloromethane organic phase, drying, condensation and recovery of dichloromethane followed by distillation of organic phase in vacuum and collected fraction of 1-chloro-3.3-dimethylbutylacetate acid is added to it, and obtained mixture is heated to 100 °C-110 °C for hydrolytic disproportionation in presence of catalyst to obtain a mixture containing 3.3-dimethylbutyraldehyde and subsequent purification of mixture by distillation to obtain purified 3.3-dimethylbutyraldehyde.EFFECT: proposed method allows to produce end product with purity higher than 99, 7 %, and output of 95 % by controlled two-stage reaction using readily available material.10 cl, 1 dwg, 3 ex

ethod for continuous hydroformylation of olefins c2-c8 // 2585285
FIELD: chemistry.SUBSTANCE: invention relates to continuous hydroformylation of olefins C2-C8. Proposed method comprises feeding in reactor raw material, synthesis gas and recycled catalyst solution containing rhodium complexes, organophosphorus ligands and heavy by-products, carrying out chemical reaction hydroformylation, isolated from reactor outlet liquid phase, evaporation of liquid phase separation on product aldehydes, followed by purification and fractionation of catalyst solution, from which part of heavy by-products are separated from catalyst by membrane nano filtration and removed, and remaining after this catalyst solution is returned to system. At that, after evaporation separation aldehydes on nano filtration only part of recycled catalyst solution that is preliminarily diluted with solvent, and remaining part of recycled catalyst solution is fed directly into reactor bypassing stage of nano filtration. At that, fed on nano filtration stream is kept in mass amount determined by empirical formula: P·Nt·Kt/St ISP, where P is efficiency at aldehydes, Nt is normal formation of heavy products per unit mass of produced aldehydes, St ISP is concentration of heavy products in catalyst solution at output of evaporator, Kt is empirical coefficient selected in range of 2…5, wherein concentration of heavy products in solution equal to St ISP, is maintained within range of 0.8…0.95 wt, and as solvent for dilution of catalyst solution to be directed for nano filtration, product aldehydes are used added in filtered flow in weight ratio of 1:1…1:5, before dilution aldehydes via catalyst solution inert gas or hydrogen is passed for 3-10 minutes with volume ratio of gas and catalyst solution not less than 10:1, after nano filtration retentate is directed to evaporation stage separation of aldehydes from catalyst solution for regeneration of diluent and retained by return catalyst and diluent of permeate is removed at rectification of main flow of product aldehydes.EFFECT: proposed method allows to reduce losses of catalytically active largest complex and organophosphorus ligand with removal of heavy by-products of condensation of aldehydes, as well as reducing speed and normal formation above heavy products.1 cl, 3 dwg, 1 tbl, 18 ex

ethod for producing geranial // 2579122
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing geranial, which is used in perfumery as flavouring agents and perfumes, of a mixture of isomers geranial and neral (citral). Method is based on carrying out transformations citral in the presence of acid catalysts, preferably, Montmorillonite clay, leading to preferred expenditure neral by formation of oligomers, and indent geranial′ unaffected. Separation of geranial from the reaction mixture can be performed column chromatography or by distillation at low pressure.EFFECT: proposed method allows to obtain an end product using simple and efficient technology on the basis of available and cheap citral.1 cl, 5 ex

Oxide catalyst // 2575346
FIELD: chemistry.SUBSTANCE: invention discloses an oxide catalyst for use in an olefin and/or alcohol oxidation reaction, a method of producing said catalyst and a method of producing a saturated aldehyde in the presence of said catalyst. The catalyst has the following formula (1): Mo12BiaFebCocCedAeBfOq (1), where Mo is molybdenum, Bi is bismuth, Fe is iron, Co is cobalt, Ce is cerium, A is at least one element selected from a group consisting of cerium and rubidium, B is at least one element selected from a group consisting of copper, nickel, magnesium and lead, a-f denote the atomic ratio of each of the elements to 12 Mo atoms; 2≤a≤6, 2.5<b≤5, 2≤c≤8, 0.4≤b/c≤2.5, 0.5≤d≤6, 0.01≤e≤2 and 0≤f<2, and g is the number of oxygen atoms, defined by the valence of the constituent element other than oxygen, wherein when the parameter d of a cerium and molybdenum composite oxide, which indicates a peak at 33.50° on an X-ray diffraction pattern, is taken as the reference, the level of change of d is 5000-9000 ppm. The method of producing the catalyst includes the following steps: ageing a suspension of the starting material containing molybdenum, bismuth, iron, cobalt and cerium at a temperature higher than room temperature; drying the aged suspension of the starting material; pre-calcining the dried product at 120°C or higher and 350°C or lower; and final calcining of the pre-calcined product at 400°C or higher and 700°C or lower.EFFECT: oxide catalyst causes less formation of subsequent oxide in an olefin and/or alcohol oxidation reaction and can improve selectivity of unsaturated aldehyde.3 cl, 2 dwg, 9 tbl, 23 ex

2,6-diisobornyl phenol derivatives // 2575294
FIELD: chemistry.SUBSTANCE: invention relates to the novel sterically hindered phenols which are intermediate compounds for the further functionalisation of 2,6-diisobornyl phenol,, where the isobornyl fragments have the configuration (1S, 2R, 4R, 1'R, 2'S, 4'S), where the isobornyl fragments have the configuration (1S, 2R, 4R, 1'S, 2'R, 4'R) and (1R, 2S, 4S 1'R, 2'S, 4'S), R1 is a formyl group or a group of general formula II -(CH2)nNX2, where X is a C1-C8 alkyl radical, straight or branched, cyclohexyl-, morpholine-, piperidine-, benzyl-, salsolidine, salsoline, N-benzyl-1-phenylethylamine, n=1-10.EFFECT: high output.2 cl, 2 ex

ethod for obtaining 4,4'-diformyldiphenylalkane // 2575126
FIELD: chemistry.SUBSTANCE: claimed invention relates to method for obtaining 4,4'-diformyldiphenylalkane, represented by means of the following formula (2), which is suitable as different industrial chemical initial substances and in production of initial substances for medications, agrochemicals, optic and electronic functional materials. Method includes formylation of diphenylalkane, represented by means of the following formula (1), with carbon monoxide in presence of fluorohydrogen and boron trifluoride, in which temperature of formylation reaction constitutes from -50 to 5°C, from 5 to 30 mol of fluorohydrogen are used per 1 mol of diphenylalkane and from 1.5 to 5 mol of boron trifluoride are used per 1 mol of diphenylalkane: in which R represents alkanediyl group, containing from 1 to 6 carbon atoms, in which R represents alkanediyl group, containing from 1 to 6 carbon atoms.EFFECT: claimed method makes it possible to obtain target products with high degree of purity and with high output.6 cl, 1 tbl, 8 ex

ethod of obtaining carbonyl compounds c2-c4 // 2570818
FIELD: chemistry.SUBSTANCE: invention relates to method of obtaining carbonyl compounds, namely ketones and aldehydes C2-C4, which find different application as valuable semi-products of FINE and basic organic synthesis, as well as are widely applied as solvents. Method is carried out in gas phase by interaction of nitrous oxide with mixture of aliphatic C2-C4 olefins and alkanes at temperature 300-550°C and pressure 1-100 atm.EFFECT: method makes it possible to obtain valuable target products with high productivity and high total selectivity with explosion safety of work.12 cl, 4 tbl, 30 ex

ethod for prolonged heterogeneous catalysed partial gas-phase oxidation of propylene to acrolein // 2568636
FIELD: chemistry.SUBSTANCE: invention relates to a method for prolonged heterogeneous catalysed partial gas-phase oxidation of propylene to acrolein. According to said method, an initial reaction gas mixture containing propylene, molecular oxygen and at least one inert gas, the molar ratio of molecular oxygen to propylene O2:C3H6 in which is ≥1:1, is passed through a fixed catalyst bed, the active mass of which is at least one polymetal oxide, containing the following elements: molybdenum, iron and bismuth, under the condition that the fixed catalyst bed is ordered in two spatially consecutive temperature zones A and B. Both the temperature of the temperature zone A (TA) and the temperature of the temperature zone B (TB) is in the range of 280 to 420°C. The initial reaction gas mixture passes through temperature zones A and B in the time sequence "first A, then B", wherein the temperature zone A continues until the degree of conversion of propylene (UA) contained in the initial reaction gas mixture is 45 to 85 mol %, while the degree of conversion of propylene in the temperature zone B rises to a value UB≥90 mol %, where when the initial reaction gas mixture passes through the common fixed catalyst bed once, selectivity of formation of acrolein with respect to the converted propylene is ≥80 mol %, the loading of the fixed catalyst bed with propylene contained in the initial reaction gas mixture is ≥140 nl propylene per litre of the fixed catalyst bed per hour; after loading a fresh fixed catalyst bed, temperatures TA and TB are such that the difference TBA=TB-TA is greater than 0°C; and then in order to counteract the deterioration of quality of the fixed catalyst bed as the duration of the production increases, at least one of the temperatures TA or TB is raised. At least one of the two temperatures TA and TB is raised such that as the duration of the production process increases, the difference ΔTBA=TB-TA increases.EFFECT: method prolongs the service life of a fixed catalyst bed with satisfactory selectivity of formation of acrolein.20 cl, 2 tbl, 1 ex

ethod of producing terephthalic aldehyde // 2568439
FIELD: chemistry.SUBSTANCE: terephthalic aldehyde is obtained from α,α,α',α'-tetrabromo-p-xylene while heating, followed by extraction of the end product. The method includes reacting α,α,α',α'-tetrabromo-p-xylene with O,O-dimethyl methylphosphonate at 180°C, and the end product is extracted from the reaction mass with isooctane.EFFECT: method enables to obtain an end product with high output using a simple technique.2 ex
ethod of production of aroma compound including compound of two solid substances having organoleptic properties // 2565721
FIELD: metallurgy.SUBSTANCE: invention relates to the method of production of the aromatic powder compound characterised by the melt point Tm exceeding or equal to 30°C. Separately to the mixer at least two main powder simple solid substances with the organoleptic properties are supplied, their melt point exceeds or is equal to 40°C. The mixer chamber was pre-heated to temperature below Tm. The said solid substances are mixed in the mixer upon absence of any external liquid phase at temperature below Tm. At least, one of the said powder solid substances is supplied to the said mixer at temperature Ti selected such that T-20°C≤Ti≤T+20°C. Mixing is performed under isothermal conditions at temperature set to the specified temperature. The said aromatic powder compound is removed.EFFECT: aromatic compound is characterised by the required size of particles without use of the grinding stage, has improved fluidity and has no caking during storage.15 cl, 3 ex

ethod for continuous hydroformylation of c3-c21 olefins into aldehydes // 2562971
FIELD: chemistry.SUBSTANCE: invention relates to a method for continuous hydroformylation of C3-C21 olefins into aldehydes in the presence of a catalyst system consisting of separate components - a soluble rhodium compound, a diphosphite ligand and an additional promoting organophosphorus ligand, selected from monophosphine, diphosphine or monophosphite. The method includes, while performing hydroformylation, controlling the value and rate of change of regioselectivity of the process on straight-chain aldehydes, periodically adding to the reaction mixture a disphosphite ligand in amount of 0.1-1 mol per 1 mol of the loaded rhodium and a promoting ligand in amount of 0.1-10 mol per 1 mol of the loaded rhodium, wherein the disphosphite ligand is added when regioselectivity decreases to a value not lower than 80%, and the promoting ligand is added when the rate of decrease of regioselectivity increases by more than 20% relative to the rate of the first decrease of regioselectivity after starting the hydroformylation process.EFFECT: method reduces consumption of the diphosphite ligand with high regioselectivity of the catalyst system on straight-chain aldehydes.1 dwg, 1 tbl, 6 ex
ethod of producing 3-chloromethyl-4-methoxybenzaldehyde // 2561730
FIELD: chemistry.SUBSTANCE: method includes chloromethylation of 4-methoxybenzaldehyde with formaldehyde, which is used in the form of paraform, the reaction being carried out in the presence of concentrated hydrochloric acid at 70-75°C while stirring. A reaction mixture is fed into the chloromethylation reaction, wherein the ratio of formaldehyde to 4-methoxybenzaldehyde in the reaction mixture is equal to 1.1-1.8:1. The reaction mass is then heated and stirred for 2.5-3.5 hours, followed by cooling to temperature of -5°C to -10°C. The precipitate is filtered out, dried on air and recrystallised from hexane.EFFECT: method enables to obtain a pure end product with high output using a simple and safe technique.4 ex

ethod of obtaining carbamide-formaldehyde concentrate // 2561722
FIELD: chemistry.SUBSTANCE: invention relates to method of obtaining carbamide-formaldehyde concentrate with mole ratio carbamide:formaldehyde 1:(4.9-5). Method includes oxidative dehydration of methanol in formaldehyde on silver or iron-molybdenum catalyst in one or several tubular or shelf-type reactors and chemical absorption of formaldehyde-containing gas in two successively placed column apparatuses. Abgas from first column apparatus is divided into two parts with ratio 1:4 with supply of smaller one to catalytic after-burning, and larger one into second column apparatus for chemical absorption by 15-25% carbamide solution with formation of prepolymer with molar ratio carbamide:formaldehyde, equal (0.1-0.5):1, mixed with 50-65% water solution of carbamide in flow mixer and supplied further for chemical absorption of formaldehyde-containing gas into upper section of first column apparatus.EFFECT: invention makes it possible to optimise scheme of obtaining carbamide-formaldehyde concentrate in order to increase efficiency of production and reduce formaldehyde content in abgas, supplied into reactor of oxidative methanol dehydration.1 dwg, 1 ex

ethod for continuous two-step hydroformylation of c3, c4 olefins and process apparatus therefor // 2561171
FIELD: chemistry.SUBSTANCE: method includes feeding into a first stage reactor fresh olefin and synthesis gas, a recirculating catalyst solution containing a rhodium complex, organophosphorus ligands, product aldehydes and heavy by-products; performing a hydroformylation chemical reaction; separating from the gas-liquid outlet of the first stage reactor unreacted synthesis gas, followed by dividing the remaining part into product aldehydes, a hydrocarbon fraction containing an unreacted olefin and a catalyst solution and recirculating the latter into the first and second stage reactors; feeding the hydrocarbon fraction and unreacted synthesis gas into the second stage reactor; the method characterised by that conversion in reactors of both stages is kept in the range of 75…92% with respect to the fed olefin, and the ratio of the amount of the catalyst solution fed into the first stage reactor to the amount of the catalyst solution fed into the second stage reactor is kept in the range of 3…10; wherein during the hydroformylation process, conversion of heavy products in the recirculating catalyst solution is kept in the range of 80-95% by removing part of the catalyst solution, thereby providing constant concentration of rhodium by feeding a fresh rhodium precursor, and regioselectivity of the process on linear aldehydes is kept higher than 90% by constantly feeding a diphosphite ligand. Inert gases and gaseous by-products are removed from the outlet of the second stage hydroformylation reactor, and all of the remaining catalyst-containing liquid phase is fed into the first stage reactor, wherein separation of product aldehydes from the catalyst solution contained in the outlet of first stage reactor is carried out in a film evaporator, which is blown with a synthesis gas stream separated from the outlet of the first stage reactor. The catalyst solution separated in the evaporator, when removing from the blowing area with synthesis gas, is cooled immediately. The invention also relates to a process apparatus for realising the disclosed method.EFFECT: invention reduces loss of the feed stock, increases specific output of the end product and increases specific capacity of the reaction volume.2 cl, 1 dwg, 2 tbl, 5 ex

Installation for obtaining aldehydes by hydroformylation of c3-c4 olefins with application of catalytic rhodium-based system // 2559052
FIELD: chemistry.SUBSTANCE: installation includes: connected to reactor in parallel way via purification devices sources of synthesis-gas and olefin, successively connected via pipelines with product output from reactor gas-liquid high-pressure separator, device for separation of product aldehydes from catalyst solution, connected with reactor by pipeline of catalyst solution recycle, collector of product aldehyde, rectification column, connected with pipeline of catalyst solution recycle unit of waste catalyst collection and unit of feeding fresh catalyst, as well as line of gas recycle. Installation is provided with gas-liquid separator of low pressure with regulator of gas pressure and stripper, successively installed between gas-liquid high-pressure separator and device for separation of product aldehydes from rhodium-containing catalyst solution, made in form if film evaporator, installed on output of exhaust gases from collector of product aldehyde compressor, refrigerator-condenser and additional high-pressure separator, with output for gas from main high-pressure separator being connected with stripper, output for gas in which is connected with line of gas recycle, with outputs for gases of low-pressure separator and additional high-pressure separator being connected with film evaporator, input of which and stripper are connected with source of synthesis-gas.EFFECT: realisation of hydroformylation on claimed installation makes it possible to increase degree of extraction and re-use of raw material, which does not react during one passage through reactor, increase total conversion of olefins, reduce thermal destruction of catalyst and loss of product aldehydes in the process of separating the latter from catalyst solution, as well as reduce loss of catalyst in the process of catalyst solution recycle.1 dwg, 1 ex

Catalyst for ethanol processing and method of obtaining acetaldehyde and hydrogen from ethanol with application thereof // 2558368
FIELD: chemistry.SUBSTANCE: catalyst represents mesoporous silica gel (Ssp.=100-300 m2/g) with applied on its surface silver in a quantity of 1-8% of the catalyst weight, which is in a highly disperse (nanosize) condition with the average size of particles of 2.8 nm. The claimed catalyst contains one or several oxides from CeO2, MnOx, ZrO2, FeOx with their summary content of 0.5-8% of the catalyst weight. The claimed invention also relates to methods of obtaining acetaldehyde and acetaldehyde together with hydrogen.EFFECT: catalyst has high activity in the transformation of ethanol into acetaldehyde.3 cl, 3 dwg, 3 tbl, 7 ex

Technological installation for obtaining aldehydes, mainly from butanes or propylene, with application of rhodium catalysts // 2557062
FIELD: chemistry.SUBSTANCE: installation comprises: sources of synthesis-gas and olefins, connected to reactor via purification devices, successively connected by means of pipelines with reactor input gas-liquid separator and evaporator, collector of bottom residue of which is connected with reverse pipeline of liquid recycle, with output of aldehydes from evaporator being collected with rectification column via collector-separator, as well as unit for discharge of waste catalyst and heavy reaction products. Installation is provided with sensor of liquid level, installed in collector of bottom residue; device for preparation of fresh catalyst solution, connected with reverse pipeline of liquid recycle and made in form of mixer with dosing device of catalyst components, with unit for discharge of waste catalyst and heavy reaction products being made in from of successively connected pump with device of its switching on and off, meter of liquid flow, device for distilling aldehydes from waste catalyst solution and connected with meter of liquid flow and dosing device of catalyst components of actuator, with output for aldehydes from device for their distillation from waste catalyst solution being connected with mixer of device for preparation of fresh catalyst solution, and sensor of liquid level is located with device of pump switching on and off.EFFECT: realisation of hydroformylation on claimed installation makes it possible to provide constant optimal quantity of heavy reaction products, optimal composition and quantity of catalyst solution.1 dwg, 1 ex

Regulation of ratio aldehyde of normal structure: aldehyde of iso-structure in process of hydroformylation with mixed ligand by regulation of synthesis-gas partial pressure // 2546110
FIELD: chemistry.SUBSTANCE: invention relates to method of regulating hydroformylation process for obtaining aldehydes of normal structure (N) and iso-structure (I) with ratio N:I. Claimed method includes contact of unsaturated olefin compound with synthesis-gas and catalyst, which contains transition metal and organopolyphosphite and organomonophosphite ligand, with contact being carried out in conditions of hydroformylation, including partial pressure of synthesis-gas, where method includes increase of partial pressure of synthesis-gas to reduce ratio N:I or reduction of partial pressure of synthesis-gas to increase ratio N:I.EFFECT: obtaining aldehydes of normal structure (N) and iso-structure (I) with ratio N to I.10 cl, 1 ex
Catalyst and method of obtaining branched unsaturated aldehydes // 2545069
FIELD: chemistry.SUBSTANCE: claimed invention relates to continuous method of obtaining branched unsaturated aldehydes, which can be used for obtaining branched alcohols or acids. method includes preparation of raw material, containing from 5 to 90 wt % of Cn aldehyde, in which n equals from 3 to 8, with raw material additionally containing from 10 to 95 wt % of solvent, interaction of raw material with resin, with resin containing acidic functional groups and not containing a metal from group VIII; reaction of mixture with resin with obtaining effluent flow, containing from 5 to 99.99 wt % of branched unsaturated C2n aldehyde and characterised by reaction selectivity constituting not less than 92%, with formation of branched unsaturated C2n aldehyde; removal of at least part of branched unsaturated C2n aldehyde from effluent flow; and optionally recirculation of part of effluent flow for re-use in raw material. Invention also relates to system for claimed method realisation.EFFECT: elaboration of continuous method of obtaining branched unsaturated aldehydes.12 cl, 1 tbl, 6 ex

ethod of hydroformylation by means of double open-end bisphosphite ligand // 2541537
FIELD: chemistry.SUBSTANCE: invention relates to method of hydroformylation and can be used in chemical industry. Claimed is method of hydroformylation for obtaining aldehyde product, including interaction in mode of continuous reaction in liquid phase for hydroformylation of unsaturated olefin compounds, carbon monoxide and hydrogen in presence of mixture of triphenylphosphine and organo-bisphosphite ligand of formula , where R1 and R2 represent monovalent aryl radical, containing from 6 to 40 carbon atoms, R28 represents C1-20-alkyl or cycloalkyl radical or alkoxyradical; and R29 can represent hydrogen atom, C1-20-alkyl or cycloalkyl radical or alkoxyradical. One of said ligands binds with rhodium with formation of hydroformylation catalyst, with molar ratio of triphenyl to metal and organo-bisphosphite ligand to metal constituting at least 4.EFFECT: presence of organomonophosphite in said system of catalysts based on Rh/organopolyphosphite complex results in catalysts stabilisation without loss of reaction rate.10 cl, 5 ex, 2 tbl
ixtures, used in oxidation of alkylaromatic compounds // 2540276
FIELD: chemistry.SUBSTANCE: invention relates to a mixture for oxidation of an alkylaromatic compound, containing: an alkylaromatic compound, a solvent, a brome source and a catalyst, with the solvent containing carboxylic acid, containing from 1 to 7 carbon atoms, as well as a ionic liquid, selected from the group, consisting of an imidazole ionic liquid, pyridine ionic liquid, phosphonium ionic liquid, tetraalkylammonium ionic liquid and their combinations, and, optionally, water; with the solvent being characterised by a ratio of the ionic liquid to carboxylic acid, being in the range from 1:10 to 10:1 by weight; and the catalyst contains, at least, one of the group: cobalt, titanium, manganese, chrome, copper, nickel, vanadium, iron, molybdenum, tin, cerium and zirconium.EFFECT: application of the method makes it possible to regulate the amount of admixtures in the solid product of oxidation.9 cl, 1 tbl, 9 ex

ethod of regioselective obtaining of n-pentanal // 2536048
FIELD: chemistry.SUBSTANCE: invention relates to regioselective obtaining of n-pentanal, which is used for obtaining plasticisers, additives to motor oils, synthetic lubricating materials. The method is realised in a medium of an aldehyde-containing solvent by the interaction of synthesis-gas with an industrial butane-butene fraction in the presence of a catalytic system, containing rhodium and a diphosphite ligand, with the reaction being carried out with the content of the aldehyde in the solvent not less than 10 wt %, at temperatures 80-110°C, total pressure 0.7-3 MPa, synthesis-gas pressure 0.5-2.5 MPa, with a molar ratio of hydrogen to carbon oxide being in the range 5.0-0.5, molar ratio diphosphite/Rh being in the range 3-15, and rhodium concentration constituting 30-300 ppm, and the addition into a reaction mixture of antioxidants, selected from bisphenols of general formulas: the content of which constitutes 10-40 mol per 1 g-at. rhodium, where R stands for hydrocarbon univalent radicals or hydrogen.EFFECT: elaboration of a method of regioselective obtaining of n-pentanal.1 tbl, 26 ex

Novel aldehydes and nitriles, obtained from isophorone, and application thereof in perfumery // 2535784
FIELD: chemistry.SUBSTANCE: invention relates to novel compounds of formula (I), which can be applied as an aromatic compound or a smell-masking agent. In formula (I) R stands for a hydrogen atom, C1-C6 alkyl, C2-C6 alkenyl or =CH2; Z stands for CN or CHO; and there is not more than one dashed bond. The following conditions must be observed: if Z stands for CHO and there is one of the dashed bonds, R does not stand for a hydrogen atom, and if there is a dashed bond between carbons Ca and Cb, R does not stand for a group = CH2. The invention also relates to a method of obtaining a formula (I) compound, its application as the aromatic compound or the smell-masking agent, and a perfumery composition.EFFECT: increased activity of the composition application.10 cl, 1 tbl, 10 ex

Specific branched aldehydes, alcohols, surfactants and consumer products based thereon // 2532165
FIELD: chemistry.SUBSTANCE: invention relates to a novel acyclic aldehyde having 16 carbon atoms, containing at least three branches and selected from a group consisting of: 3-ethyl-7,11-dimethyldodecanal, 2,3,7,11-tetramethyl-dodecanal, 7,11,-dimethyl-3-vinyldodeca-6,10-dienal and 4,8,12-dimethyltrideca-4,7,11-trienal, to a composition of substances suitable for use as starting material for producing surfactants and containing at least one of the disclosed acyclic aldehydes, to a composition of detergent alcohols, suitable for producing a composition of surfactants and containing at least one acyclic alcohol converted from the disclosed acyclic aldehyde, and to a surfactant composition suitable for use in a detergent or cleaning composition and containing one or more surfactant derivatives of isomers of the acyclic detergent alcohol converted from the disclosed acyclic aldehyde. The invention also relates to versions of a cleaning composition and to versions of a method of producing an alcohol mixture for a composition of detergent alcohols.EFFECT: improved properties of compounds.19 cl, 10 tbl, 24 ex

ethod of obtaining acrolein from glycerol or glycerine // 2531277
FIELD: chemistry.SUBSTANCE: invention relates to an improved method of obtaining acrolein from glycerol. Dehydration of glycerol is carried out in the presence of a catalyst based on zirconium oxide, consisting at least of: a) mixed zirconium oxide and at least of one metal M, where the said metal is selected from niobium and vanadium, b) zirconium oxide and at least one metal M oxide, where the said metal is selected from niobium, tantalum and vanadium, c) silicon oxide and mixed zirconium oxide and at least one metal M, where the said metal is selected from tungsten, cerium, manganese, niobium, tantalum, titanium, vanadium and silicon, d) titanium oxide, mixed zirconium oxide and at least one metal M, where the said metal is selected from tungsten, cerium, manganese, niobium, tantalum, titanium, vanadium and silicon. The invention also relates to a method of obtaining 3-(methylthio)propionic aldehyde from acrolein and to application of a catalyst, selected from the catalysts a), b), c) or d) for conversion of glycerol into acrolein.EFFECT: method makes it possible to obtain acrolein by catalytic dehydration of glycerol in the presence of catalyst, which provides conversion of all initial glicerine and at the same time can be easily regenerated during short time without losing activity and selectivity and possesses a long service term.13 cl, 4 dwg, 5 tbl, 18 ex

ethod of producing aldehydes // 2527455
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing aldehydes via hydroformylation of terminal or internal olefins in the presence of a catalyst system containing rhodium and a mono- or polyphosphite ligand. An antioxidant is added to the reaction mixture, the antioxidant being phenols or thioureas of general formulae: where R denotes identical or different aliphatic or aromatic univalent radicals or hydrogen, and hydroformylation is carried out in liquid phase in a solvent medium in form of aldehyde, with rhodium concentration of 0.1-2 mmol/l, at temperature of 20-150°C and pressure of 0.2-5 MPa, wherein the amount of the antioxidant is 1-30 mol/mol phosphite ligand.EFFECT: invention enables to obtain end products using an efficient method at low raw material costs.2 tbl, 15 ex
ethod of oxidising alkyl aromatic compounds // 2524947
FIELD: chemistry.SUBSTANCE: invention relates to a method and a mixture for oxidising an alkyl aromatic compound. The mixture contains: an alkyl aromatic compound, a solvent, a bromine source, a catalyst and ammonium acetate; wherein the solvent includes a carboxylic acid having 1-7 carbon atoms and optionally water, and the catalyst substantially consists of at least one metal selected from cobalt, titanium, manganese, chromium, copper, nickel, vanadium, iron, molybdenum, tin, cerium and zirconium, present in form of acetates or hydrates thereof.EFFECT: present invention enables to obtain products of higher purity which enables to eliminate or minimise purification costs.10 cl, 1 tbl, 3 ex

ethod of methyl methacrylate purification // 2523228
FIELD: chemistry.SUBSTANCE: invention relates to a method of methyl methacrylate (MMA) purification, which includes realisation of contact of a liquid MMA, containing admixtures, with a sulphonic acid resin in the presence of formaldehyde or an acceptable source of methylene or ethylene of formula I, as is determined below, where R5 and R6 are independently selected from C1-C12 hydrocarbons or H; X represents O; n is an integer number from 1 to 100; and m has a value of 1 or 2, and in which the sulphonic acid resin is optionally, at least, partially, deactivated.EFFECT: method makes it possible to remove admixtures of an aldehyde type, dienes, trienes with high efficiency.18 cl, 20 tbl, 1 dwg, 8 ex
ethod of vanillin manufacturing // 2519550
FIELD: chemistry.SUBSTANCE: method consists in air oxygen oxidation of lignin, obtained by fermentative hydrolysis of wood of coniferous species or wood, affected by brown or mottled rot, with content of lignin 40-90 wt % in water-alkali medium at higher temperatures and pressure. The process is carried out in presence of catalysts on the basis of copper hydroxide with continuous supply of alkali solution into reactor for 1-150 minutes.EFFECT: method makes it possible to reduce alkali consumption counted per a kilo of obtained vanillin, and consumption of fermentative lignin, which reduces amount of organic substance, formed as byproducts, in sewage water and improves ecological compatibility of the process.10 ex

ethod of obtaining apoptosis stimulator abt-263 // 2514935
FIELD: chemistry.SUBSTANCE: invention relates to method of obtaining N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperasin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzolsulfonamide or its pharmaceutically acceptable salt, which includes: (a) interaction of 4,4-dimethylcyclohexanone, alkylformiate, selected from group, including methylformiate, ethylformiate, n-propylformiate, tertbutylformiate and their any combination, and first base, selected from group, including sodium hydrate, sodium tert-butoxide, potassium tert-butoxide and their any combination, with obtaining (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone, with separation or without separation of (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone; (b) interaction of (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone, second base, selected from group, including triethylamine, 2,6-lutidine, pyridine, imidazole, diisopropylethylamine, N-methylmorpholine, dimethylaniline and their any combination, and first reagent silyl ether protecting group, selected from group, including trimethylchlorosilane, tert-butylchlorodimethylsilane, triisopropylchlorosilane, tert-butylchlorodiphenylsilane and their any combination, with obtaining first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone, with separation or without separation of first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone; (c) interaction of first protected (2E)-2-(hydroxymethylene)-4,4-dimethylcyclohexanone and 4-chlorophenylmagnesium bromide with obtaining first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)-4,4-dimethylcyclohexanol; with separation or without separation of first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)-4,4-dimethylcyclohexanol; (d) interaction of first protected (2E)-1-(4-chlorophenyl)-2-(hydroxymethylene)-4,4-dimethylcyclohexanol and first acid, selected from group, including tetra-n-butylammoniumfluoride, trifluoroacetic acid, hydrochloric acid, sulfuric acid and any their combination, with obtaining 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-carbaldehyde, with separation or without separation of 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-carbaldehyde; (e) interaction of 2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-carbaldehyde, ethyl 4-piperazin-1-ylbenzoate and first reducing agent, selected from group, including sodium triacetoxyborohydrode, sodium cyanoborohydride and their combinations, with separation or without separation of ethyl 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-yl)methyl)piperazin-1-yl)benzoate; (f) ethyl 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-yl)methyl)piperazin-1-yl)benzoate interaction of and aqueous solution of third base, selected from group, including sodium hydroxide, potassium hydroxide and their combinations, with separation or without separation of 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-yl)methyl)piperazin-1-yl)benzoic acid; and (g) interaction of 4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-ene-1-yl)methyl)piperazin-1-yl)benzoic acid, 4-(((1R)-3-morpholin-4yl-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzolsulfonamide and first binding reagent, selected from group, including 1-ethyl-3(3-(dimethylamino)propyl)-carbodiimidhydrochloride, dicyclohexylcarbodiimide, N,N'-diisopropylcarbodiimide, 1,1'-carbonyldiimidasole and their any combination, with or without fourth base, selected from group, including 1,8-diazabicyclo(5.4.0)undec-7-ene, potassium tret-butoxide and their combinations, and with or without first auxiliary binding reagent, selected from group, including 4-dimethylaminopyridine, hydroxybenzotriazole, 1-hydroxy-7-aza-benzotriazole and any their combination, with separation or without separation of N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperasin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzolsulfonamide.EFFECT: new method of obtaining N-(4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohex-1-en-1-yl)methyl)piperasin-1-yl)benzoyl)-4-(((1R)-3-(morpholin-4-yl)-1-((phenylsulfanyl)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)benzolsulfonamide, which can be applied in medicine as stimulator of apoptosis.10 cl, 17 ex

ethod of purifying glyoxal water solution // 2510616
FIELD: chemistry.SUBSTANCE: invention relates to improved method of purification of glyoxal water solution by successive running of purified solution through electrodialyser chambers, separated with anion-exchange and cation-exchange membranes. Purification is performed by asymmetric alternating current of controlled frequency with the following parameters: frequency f=5-2000 Hz, voltage Um=0.1-500 V, ratio of direct and reverse current Jmn:Jm0=2:1−12:1, with water solutions of alkali metals, ammonium carbonates or ammonium bicarbonates serving as collectors of admixtures in purification of glyoxal water solutions, and rate of solutions constitutes from 0.001 to 100 m/s. Invention also relates to device for purification of glyoxal water solutions.EFFECT: method makes it possible to increase process selectivity and makes it possible to carry out purification of highly concentrated glyoxal solutions.2 cl, 2 dwg, 1 tbl, 2 ex

Silver catalyst for obtaining formaldehyde // 2503497
FIELD: chemistry.SUBSTANCE: invention relates to field of catalyst. Described is method of obtaining silver crystals with distribution of average size of particles from 0.15 mm to 2.5 mm and porous coating of oxide materials in which a) silver crystals contact with sol-gel solution of said materials, in solvent, which contains organic solvent and b) obtained as a result silver crystals are collected, c) released from organic solvent and d) then subjected to thermal processing at temperature between 50°C and point of silver melting. Described is application of obtained crystals as catalyst for obtaining formaldehyde.EFFECT: increased activity of catalyst for obtaining formaldehyde.10 cl, 3 dwg, 4 tbl, 1 ex

ethod of making catalytically active geometric moulded articles // 2495719
FIELD: chemistry.SUBSTANCE: described is a method of making catalytically active geometric moulded articles K, which contain as active mass, a multi-element oxide I with general stoichiometric formula (I): [BinZ1 bOx]p[BicMo12FedZ2 eZ3 fZ4 gZ5 hZ6 iOy]1 (I), according to which Z1 denotes tungsten or tungsten and molybdenum, under the condition that the amount of tungsten is at least 10 mol % of the total molar amount Z1, Z2 denotes an element or multiple elements selected from a group which includes nickel and cobalt, Z3 denotes an element or multiple elements selected from a group which includes alkali metals, alkali-earth metals and gallium, Z4 denotes an element or multiple elements selected from a group which includes zinc, phosphorus, arsenic, boron, antimony, tin, cerium, vanadium and chromium, Z5 denotes an element or multiple elements selected from a group which includes silicon, aluminium, titanium, tungsten and zirconium, Z6 denotes an element or multiple elements selected from a group which includes copper, silver, gold, yttrium, lanthanum and lanthanides, a is a number from 0.1 to 3, b is a number from 0.1 to 10, d is a number from 0.01 to 5, e is a number from 1 to 10, f is a number from 0.01 to 2, g is a number from 0 to 5, h is a number from 0 to 10, i is a number from 0 to 1, p is a number from 0.05 to 6, and x, y are respectively numbers defined by valence and number of atoms other than oxygen atoms in formula (1), wherein a fine mixed oxide BiaZ'bOx is formed in form of a starting mass A1, the particle diameter d50A1 of which satisfies the condition 1 mcm≤d50A1≤100  mcm, using sources, other than oxygen, of elements of the component part T of the multi-element oxide I, represented by [BicMo12FedZ2cZ3 fZ4 gZ5 hZ6 iOy]i, a homogeneous aqueous mixture M is formed in an aqueous medium, wherein: each of the sources used when forming the aqueous mixture M passes through a dispersion degree Q, characterised by that the particle diameter corresponds to d90Q≤5 mcm, and the aqueous mixture M contains bismuth, molybdenum, iron, Z2, Z3, Z4, Z3 and Z6 in the stoichiometric formula (I*): BicMo12FedZ2 cZ3 fZ4 gZ5 hZ6 i (I*); from the aqueous mixture M, by drying and controlling the dispersion degree d90A2, a fine starting mass A2 is formed, the particle diameter d90A2 of which satisfies the condition400  mcm≥d90A2≥10 mcm; the starting mass A1 is mixed with starting mass A2 or the starting mass A1, starting mass A2 and a fine auxiliary moulding agent are mixed to obtain a fine starting mass A3, which contains elements of the multi-element oxide I other than oxygen that are introduced therein through starting mass A1 and A2, in stoichiometric formula (1**): [BiaZ'b]p[BicMo12FedZ2 eZ3 fZ4 gZ5 hZ6 i]l (I**);geometric moulded articles V are formed from the fine starting mass A3; the moulded articles V undergo heat treatment at high temperature to obtain catalytically active geometric moulded articles K, wherein the stoichiometric coefficient "c" lies in the range 0<c≤0.8.EFFECT: described is a method for heterogeneously catalysed partial gas-phase oxidation of an alkane, alkanol, alkanal, alkene and/or alkenal containing 3-6 carbon atoms in a catalyst bed, wherein the catalyst bed contains catalytically active moulded articles which can be made using said method.15 cl, 3 tbl, 13 ex

ethod of making catalytically active geometric moulded articles // 2495718
FIELD: chemistry.SUBSTANCE: invention relates to methods of producing catalytic moulded articles and use thereof. Described is a method of making catalytically active geometric moulded articles K, which contain as active mass, a multi-element oxide I with general stoichiometric formula (I): [BilWbOx]a[Mo12Z1 cZ2 dFeeZ3 fZ4 gZ5 hOy]l (I), in which Z1 denotes an element or multiple elements selected from a group which includes nickel and cobalt, Z2 denotes an element or multiple elements selected from a group which includes alkali metals, alkali-earth metals and thallium, Z3 denotes an element or multiple elements selected from a group which includes zinc, phosphorus, arsenic, boron, antimony, tin, cerium, vanadium, chromium and bismuth, Z denotes an element or multiple elements selected from a group which includes silicon, aluminium, titanium, tungsten and zirconium, Z5 denotes an element or multiple elements selected from a group which includes copper, silver, gold, yttrium, lanthanum and lanthanides, a is a number from 0.1 to 3, b is a number from 0.1 to 10, c is a number from 1 to 10, d is a number from 0.01 to 2, e is a number from 0.01 to 5, f is a number from 0 to 5, g is a number from 0 to 10, h is a number from 0 to 1, and x, y are respectively defined by valence and number of atoms other than oxygen in formula (I), wherein a fine mixed oxide BilWbOx is formed in form of a starting mass A1, the particle diameter d50A1 of which satisfies the condition 1 mcm ≤ d50A1 ≤10 mcm; a homogeneous aqueous mixture M is formed in an aqueous medium using sources, other than oxygen, of elements of the component part T=[Mo12Zl cZ2 dFeeZ3 fZ4 gZ5 hOy]l of the multi-element oxide I, wherein: each of the sources used when forming the aqueous mixture M passes through a dispersion degree Q, which corresponds to particle diameter d90Q ≤ 5 mcm, and the aqueous mixture M contains molybdenum, Z1, Z2, iron, Z3, Z4 and Z5 in the stoichiometric formula (I*): Mo12Zl cZ2 dFecZ3 fZ4 9Z5 h (I*); from the aqueous mixture M, by drying and controlling the dispersion degree, a fine starting mass A2 is formed, the particle diameter d90A2 of which satisfies the condition 200 mcm ≥ d90A2 ≥ 20 mcm; the starting mass A1 is mixed with starting mass A2 or the starting mass A1, starting mass A2 and a fine auxiliary moulding agent are mixed to obtain a fine starting mass A3, which contains elements of the multi-element oxide I other than oxygen that are introduced therein through starting mass A1 and A2, in stoichiometric formula (1**): [BilWb]a[Mo12Zl cZ2 dFeeZ3 fZ4 gZ5 h]i (I**); geometric moulded articles V are formed from the fine starting mass A3, and the moulded articles V undergo heat treatment at high temperature to obtain catalytically active geometric moulded articles K, wherein the product F:(d50A1)0,7⋅(d90A2)1,5⋅(a−1) is ≥820.EFFECT: described is a method for heterogeneously catalysed partial gas-phase oxidation of an alkane, alkanol, alkanal, alkene and/or alkenal containing 3-6 carbon atoms in a catalyst bed, wherein the catalyst bed contains catalytically active moulded articles made using said method.15 cl, 8 dwg, 10 tbl, 2 ex

ethod of producing glutaric aldehyde // 2495019
FIELD: chemistry.SUBSTANCE: invention relates to a novel method of producing glutaric aldehyde. The method involves reaction, in a vessel at temperature of 80-120°C, of a reaction mixture containing an alkoxy dihydropyran derivative of formula I wherein R denotes a C1-C2 alkyl, water and an acid catalyst to obtain glutaric aldehyde and an alcohol, corresponding to the alkoxy group of alkoxy dihydropyran. Further, a distillation column is used to remove, from the reaction mixture, a distillate containing alcohol and unreacted alkoxy dihydropyran, followed by contacting the distillate with a heterogeneous catalyst lying outside the distillation column such that at least a portion of alkoxy dihydropyran reacts and returning at least a portion of the distillate into the distillation column.EFFECT: method increases output of glutaric aldehyde.8 cl, 3 dwg, 1 tbl

ethod of purifying vanillin obtained from lignin oxidation products // 2494085
FIELD: chemistry.SUBSTANCE: invention relates to a method of purifying vanillin obtained from lignin oxidation products, by reacting vinillin-containing extracts with aqueous solutions sodium bisulphite, followed by decomposition of the vanillin-bisulphite derivative. The method is characterised by that the vanillin-bisulphite derivative is heated in an autoclave to 120-170°C, the vapour-gas phase is released and vanillin is extracted from the obtained mixture or solution, followed by recycling the obtained aqueous solution of sulphurous anhydride and sodium sulphate into a solution of sodium bisulphite.EFFECT: method enables to avoid the use of sulphuric acid and alkali when purifying vanillin, widely used in food, perfume, cosmetic and pharmaceutical industry.5 ex
 
2551286.
Up!