Chemistry and metallurgy (C)

C            Chemistry; metallurgy(315514)
C01 - Inorganic chemistry(20787)
C06 - Explosives; matches(2093)
C07 - Organic chemistry(61593)
C13 - Sugar industry(2232)
C21 - etallurgy of iron(23203)
C30 - Crystal growth(2110)

Salts and crystalline forms of apottosis-inducing agent // 2628560
FIELD: pharmacology.SUBSTANCE: invention relates to a compound having the systematic name 4-(4-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazin-1-yl)-N-({3-nitro-4-[(tetrahydro-2H-pyran-4-ylmethyl)amino]phenyl}sulfonyl)-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy) benzamide (compound 1) in the form of a free base crystalline anhydrate, a free base hydrate of crystalline form, a solvate of crystalline form, a hydrochloride salt of crystalline form, or a sulfate salt of crystalline form. The invention also relates to a pharmaceutical composition having an inhibitory activity against anti-apoptotic proteins of the Bcl-2 family comprising a therapeutically effective amount of the compound of the invention and one or more pharmaceutically acceptable excipients.EFFECT: crystalline forms of compound 1 suitable for use as an active pharmaceutical ingredient.21 cl, 14 dwg, 14 tbl, 17 ex
Oral care products, including zinc oxide and trimethylglycine // 2628540
FIELD: pharmacology.SUBSTANCE: group of inventions refers to oral care compositions, consisting of a mixture of zinc oxide and trimethylglycine (TMG), where the TMG is included into the composition in the form of hydrohalogenide, and zinc oxide and TMG form soluble complexes, selected from zinc-TMG-hydrohalogenide complexes, zinc-hydrohalogenide complexes and mixtures, where the hydrohalogenide is selected from hydrofluoride, hydrochloride and hydrobromide, as well as to a method for tooth enamel erosion treatment or mitigation, biofilm and bacterial plaque reduction, gingivitis reduction, tooth decay and cavities formation reduction, dentin hypersensitivity reduction, including application of such composition to the teeth, zinc oxide application together with the TMG in the form of hydrohalogenide during oral care composition production.EFFECT: creation of a complex, capable of yielding a solution which precipitates when diluted.15 cl, 4 ex, 6 tbl

ethod for alcoxyphenol and alcoxyhydroxybenzaldehyde production // 2628525
FIELD: chemistry.SUBSTANCE: method for alkoxyphenol production comprises O-alkylation of at least one hydroxyphenol to form at least one alkoxyphenol, at that, the said reaction is carried out using an O-alkylating agent, an aqueous solvent containing a Bronsted base and an organic solvent with a base/O-alkylating agent ration in the range of 0.5 to 1.5 moles of base per mole of O-alkylating agent, with an O-alkylating agent/hydroxyphenol ratio in the range of 0.5 to 2 moles of O-alkylating agent per mole of hydroxyphenol and with an organic solvent/hydroxyphenol ratio of less than 280 ml, preferably in the range of 10 to 250 ml and more preferably in the range of 50 to 150 ml of an organic solvent per mole of hydroxyphenol. One of the versions of the alkoxyhydroxybenzaldehyde production method comprises preparation of alkoxyphenol from hydroxyphenol by the foregoing method and a reaction of the aldehyde group addition to the resulting alkoxyphenol to obtain the corresponding alkoxyhydroxybenzaldehyde, preferably by condensation reaction between alkoxyphenol and glyoxylic acid, followed by oxidation of the resulting compound.EFFECT: proposed method for alkoxyphenol production allows the desired product to be obtained in good yield and high purity with high conversion of initial hydroxyphenol.11 cl, 3 dwg, 7 ex

ethod of regulating the volume flow of a coal-kerozine suspension and a device for manufacturing a burned coal // 2628524
FIELD: mining engineering.SUBSTANCE: invention describes a method for controlling the volumetric flow rate of a coal-kerosene suspension in which, during the separation of the solid and liquid phases by feeding the dehydrated coal-kerosene suspension to a centrifugal separator of the decanter type and separating the coal-kerosene suspension into a solid fraction and a liquid fraction, the target electric current fed to the engine to rotate it and drive the screw conveyor of the centrifugal separator of the decanter type is determined such that the liquid level In the tank for a coal-kerosene suspension fed to a centrifugal separator of the decanter type, it can take a constant value; the target opening degree value is determined based on the difference between the target electric current value and the actually measured value of the electric current supplied to the motor; and the degree of opening of the flow control valve, which is located in the middle of the feed line for introducing the coal-kerosene slurry into the centrifugal separator of the decanter type, is adjusted depending on the target degree of opening. Also, the options for ways to regulate the volume flow coal-oil suspensions and devices to perform these techniques are described.EFFECT: ability to effectively prevent overloads and mechanical damages of a centrifugal separator of the decanter type or to reduce the quality of separation of the solid and liquid phases, the ability to stabilise the process of obtaining upgraded brown coal.6 cl, 5 dwg

ethod for producing moulded solid fuel // 2628523
FIELD: chemistry.SUBSTANCE: invention describes a method for producing moulded solid fuel, comprising: a pulverization stage for pulverizing low-grade coal; a stirring stage for mixing the pulverized low-grade coal and the oil solvent to form a slurry; a dewatering stage for heating and dewatering the slurry to form an anhydrous slurry; a stage for separating solid and liquid phases to separate the oil solvent from the dehydrated slurry to form a precipitate; a drying stage for heating the precipitate to further separate the oil solvent from the precipitate to produce powdered coal of enhanced quality; and a moulding stage for compression moulding the powdered coal of improved quality by means of a moulding device without adding and/or mixing with a bonding material, in which at the stage of forming the moulding device on the surface, a cooling substance is pulverized to cool the surface and thus the surface temperature of the moulding device is maintained at 100°C or below.EFFECT: producing moulded solid fuel from low-grade coal, having high strength.6 cl, 4 ex, 1 tbl, 2 dwg

anufacture method of moulded solid fuel // 2628522
FIELD: oil and gas industry.SUBSTANCE: manufacture method of the briquetted solid fuel includes the following steps: spraying of the low quality coal to produce the pulverized low quality coal; mixing with the oil solvent to form the dewatered suspension; heating and thereby dewatering of the suspension to form the dewatered suspension; separation of the oil solvent from the dewatered suspension by liquid-solid body separation to obtain the cake; heating and thereby drying the cake, so to separate additionally the oil solvent from the cake and to obtain the refined coal in the powder form; mixing of the refined coal with the coal to control the properties in the powder form, in order to control the properties of the refined coal and thereby to obtain the feedstock for briquetting, containing the coal to adjust the properties in the amount from 5 to 70% wt %, based on the total weight of the briquetted feedstock, the mentioned carbon to control the properties, having the free bulk density 0.6 kg/l or more and the natural repose angle of 40° or less, and the feedstock briquetting for the briquetting under the pressure to produce the briquetted solid fuel in the form of briquettes.EFFECT: production of briquetted solid fuel from low-quality coal with high strength.4 cl, 1 dwg, 9 ex, 2 tbl

Systems and methods for renewable fuel // 2628521
FIELD: chemistry.SUBSTANCE: invention discloses a fuel that contains a catalytic cracking product of a fluid comprising a fuel mixture comprising: i) 93-99.95 wt % of the oil fraction material and ii) 0.05-7 wt % of the raw material of the non-enriched renewable petroleum fuel, where the non-enriched renewable petroleum fuel comprises a product of grinding and non-catalytic fast heat treatment of the cellulosic biomass with conversion of, at least, 60 wt % of cellulosic biomass into non-enriched renewable petroleum fuels, and where the non-enriched renewable petroleum fuel has a carbon content of, at least, 40 wt % on a dry basis and oxygen content in the range of 20-50 wt % on a dry basis and water content in the range of 10-40 wt %. A method of obtaining fuel is also disclosed.EFFECT: co-processing of thermally obtained biomass products with petroleum raw materials in various refining operations.20 cl, 20 dwg, 11 tbl, 3 ex

ethod of oxidative dehydration with improved regulatibility for obtaining butadiene // 2628519
FIELD: chemistry.SUBSTANCE: one of the process variants comprises the steps of providing a butene-enriched hydrocarbon feed, evaporating and superheating said butene-enriched hydrocarbon feed at a temperature of at least about 345°C (650°F), mixing said butene-rich hydrocarbon feed with superheated steam and oxygen-rich gas to form a reactor feed stream; providing a catalytic bed of oxidative dehydrogenation catalyst pellets, passing mentioned reactor feed stream from the inlet through said catalyst bed and forming a stream of a butadiene-rich product; providing a catalytic bed of oxidative dehydrogenation catalyst pellets, passing mentioned reactor feed stream from the inlet through said catalyst bed and forming a stream of a butadiene-rich product; providing mentioned catalytic oxidative dehydrogenation catalyst bed with a plurality of temperature sensing devices associated therewith for measuring the temperature in the bed in the direction of flow; controlling the inlet conditions of mentioned reactor such that oxidative dehydrogenation reactions initially take place in the layers of mentioned oxidative dehydrogenation catalyst most remote from said inlet, including reacting interaction with reactor feed stream with mentioned catalyst in the reaction zone and forming a butadiene-rich product stream; controlling the temperature over the length of the bed and occasionally increasing the temperature at the inlet so that the reaction zone migrates relative to said inlet in said oxidative dehydrogenation catalytic bed.EFFECT: use of the proposed invention avoids the effects of oxygen leaking into the catalyst.20 cl, 6 tbl, 8 dwg

Device for composting // 2628518
FIELD: agriculture.SUBSTANCE: device includes a site for collecting crushed and mixed waste, combined with a compost storage. The store is a rectangular pit with the depth up to 1 mand the width and length dimensions providing the reception of the total volume of the waste generated. The pit is framed by boards up to 0.4 m and is divided inside with slotted partitions, with the formation of sections for alternately filling them with compost mass. The sections have independent coverages. To control the composting process, tubes with thermometers are installed in each section.EFFECT: simplifying the process of obtaining environmentally-friendly organic fertiliser.2 dwg, 1 ex
ethod // 2628516
FIELD: chemistry.SUBSTANCE: invention is a method of supplying liquid feed streams in a polymerization process. Method for supplying fresh feedstock selected from a fresh comonomer and a fresh inert hydrocarbon to a polymerization reactor is described. The polymerization reactor is a part of polymerization process that includes recovery systems at a high 0.5 MPa (5 bar) or higher and a low pressure of less than 0.5 MPa (5 bar). The method comprises feeding of mentioned fresh feedstock and a process stream comprising a first component selected from hydrogen, nitrogen and methane and a second component that is a monomer to a separator at a pressure of 0.4 MPa (4 bar) or less to obtain the first stream comprising most of the first component and a second stream comprising most of the fresh feed stream and most of the second component and feeding the second stream to the polymerization reactor. Method of treating a fresh feed stream is also described.EFFECT: preparation of a polymerization process having a high efficiency for the desired components of the final polymer, for example a monomer, but a low efficiency for other components, for example hydrogen.20 cl, 3 ex

ethod for processing fats and oils // 2628515
FIELD: food industry.SUBSTANCE: method for neutralizing the acidity of fats and oils to produce micronutrients and a product of fatty acids and to extract refined oils includes: feeding the pretreated oil stream to a vacuum vapour distillation section distilling volatile phases; feeding the distilled volatile phases to the high-temperature condensation stage or to the combination of the high-temperature and the mid-temperature condensation stages to obtain the condensed phase (A) and the vapour phase (E); sending the condensed phase (A) to the vacuum distillation process and sending the vapour phase (E) to the low-temperature condensation stage; the effect on the condensed phase (A) of the vacuum distillation process and obtaining a high-temperature distillate and a stream of volatile substances; feeding the vapour phase (E) from the high-temperature condensation stage together with the stream of the volatile substances (C) from the vacuum distillation process to the low-temperature condensation stage to obtain the stream of non-condensable gases and low-temperature distillate, providing the stream of the non-condensable gases the possibility to be retained in the vacuum system, and extracting he refined oil stream from the vacuum and vapour distillation section.EFFECT: invention makes it possible to increase the content of tocopherols during the neutralisation of oils.14 cl, 12 dwg, 5 tbl, 3 ex
Grease lubricant composition // 2628512
FIELD: chemistry.SUBSTANCE: grease lubricant composition comprises base oil, thickener and poly (meth)acrylate containing hydroxyl groups, wherein said thickener is urea compound obtained by reacting between isocyanate and primary amine, and said poly(meth)acrylate containing hydroxyl groups is copolymer comprising, as composite monomers, alkyl(meth)acrylate containing C1-20 alkyl group, and vinyl monomer containing a hydroxyl group.EFFECT: high wear resistance.13 cl, 1 tbl, 10 ex

Integration of resid hydrocracking and hydrocleaning // 2628509
FIELD: oil and gas industry.SUBSTANCE: one of the process variants includes the following steps: contacting the hydrocarbon residue and hydrogen fraction with the first hydroconversion catalyst in the first fluidized bed hydroconversion reactor system; extracting the first outlet stream from the first fluidized bed hydroconversion reactor system; contacting of the first outlet stream and hydrogen with the second hydroconversion catalyst in the second hydroconversion reactor system; extraction of the second outlet stream from the second hydroconversion reactor system; contacting of the second outlet stream and hydrogen with the third hydroconversion catalyst in the second fluidized bed hydroconversion system; extracting the third outlet stream from the second fluidized bed hydroconversion reactor system; fractionating of the third outlet stream from the second fluidized bed hydroconversion reactor system to recover one or more hydrocarbon fractions, including the vacuum fraction of the hydrocarbon residue.EFFECT: invention makes it possible to achieve high hydrocarbon processing using a simplified technology.20 cl, dwg 4
Processing method of heavy vacuum gasoil // 2628508
FIELD: oil and gas industry.SUBSTANCE: residual oil vacuum distillation product, the heavy vacuum gasoil, is subjected to cryolysis, i.e. freezing, at the certain process conditions with subsequent distillation of light fuel fractions. The processing method of vacuum gasoil is included in its physical separation into fractions, where in order to increase the most valuable light fuel fractions yield, the fuel oil vacuum distillation product -vacuum gasoil is subjected to cryolysis at the temperature of not higher than -35°C for at least 20 hours with the preliminary introduction in it the donor additive (water) at least 0.5% to the gasoil weight. The invention is the alternative to the catalytic cracking process, since the process yield of the light fuel fractions at the heavy vacuum gasoil cryolysis treatment is not less than the yield, obtained by catalytic cracking.EFFECT: complete bleeding of the valuable light fuel fractions from the oil.4 ex, 1 tbl

ethods of increasing yield of agricultural crops resistant to 2,4-d // 2628504
FIELD: agriculture.SUBSTANCE: to increase the yield of soybean plants resistant to 2.4-D, they are treated with 2.4-D at the growth stage of V3 and R2 with the application rate from 1000 to 2000 g ke/ha. To increase the yield of a soybean plant resistant to 2.4-D: (a) soybean cells are transformed with the molecule of a nucleic acid comprising a nucleotide sequence encoding aryloxyalkanoate dioxygenase (AAD); (b) transformed cells undergo the selection; (c) soybean plants are regenerated from the transformed cells; and (d) 2.4-Dis applied at the growth stage of V3 and R2 of a 2.4-D-resistant soybean plant which is treated with 2.4-D at the application rate from 1000 to 2000 g ke/ha.EFFECT: invention allows to increase the soybean crop capacity.18 cl, 3 dwg, 44 tbl, 24 ex
ethod of producing ammonium sulphate // 2628493
FIELD: chemistry.SUBSTANCE: process of production solid ammonium sulfate-nitrate envisages the steps: solidifying of melt pulp, containing ammonium sulfate and ammonium nitrate in granulation bed to form solid ammonium sulfate-nitrate granules, containing ammonium sulfate-nitrate double salt 2:1, wherein the granulation layer has an operating temperature of 90 to 120°C, and solid ammonium sulfate-nitrate granules are characterised by moisture content of 0.4 wt % up to 1.5 wt %, while productional ammonium sulfate-nitrate contains less than 7 wt % of unreacted ammonium nitrate and 3:1 ammonium sulfate-nitrate double salt.EFFECT: invention makes it possible to obtain product for further use as a fertiliser that is characterised by reduced sensitivity to moisture and is not considered as hazardous material.6 cl, 4 dwg, 2 ex
Process of producing 2,3-dimethoxy-5-methyl-1,4-benzoquinone // 2628457
FIELD: chemistry.SUBSTANCE: invention relates to the method of producing 2,3-dimethoxy-5-methyl-1,4-benzoquinone, a key intermediate in the synthesis of ubiquinones (coenzymes of the Qn series), in particular of coenzyme Q10, widely used in medical practice and cosmetology, as well as its synthetic analogue - idebenone - a drug for the treatment of Alzheimer's disease. The method consists in oxidizing 3,4,5-trimethoxytoluene with hydrogen peroxide in an organic solvent medium. Herewith the acid tetrabutylammonium salts of the vanadium-containing polyoxo-tungstate (C4H9)4N)5-nHn[γ-PV2W10O40], where the number of protons n in the cationic part of the polyox-tungstate varies from 1 to 2, as co-catalyst, HClO4 with respect to the catalyst, 0.5-1 equivalents, as the organic solvent, preferably acetonitrile is used, the process is carried out at the temperature of, at least, 30°C, at the molar ratio of 3,4,5-trimethoxytoluene: the catalyst is not lower than 40 and the concentration of 3,4,5-trimethoxytoluene is not higher than 0.4M, an aqueous solution of hydrogen peroxide with a peroxide content of, at least, 30 wt %, the process is carried out at the molar ratio of hydrogen peroxide: 3,4,5-trimethoxyphenol not less than 2.EFFECT: desired product in high yield without the formation of a large amount of by-products.2 cl, 1 tbl, 23 ex

New pyrimidine inhibitors of human adenovirus replication // 2628456
FIELD: pharmacology.SUBSTANCE: invention relates to new 5-aminouracil derivatives containing 4-(phenoxy) benzyl or ω-(phenoxy)alkyl substituent in the N1 position, corresponding to the general structural formula (I). Compounds represent a new class of anti-adenoviral agents of a non-nucleoside nature. In the general formula (I), X = CH or N; Y=(CH2)2, (CH2)3, (CH2)4 or C6H4; R1= H, R2= C6H or 3,5-Cl2C6H3; R1+R2= morpholino; R3=H, F or Cl.EFFECT: compounds have a selective antiviral effect against human adenoviruses and can be used for treatment of adenoviral infections.1 dwg, 3 tbl, 11 ex
ethod of utilizing liquid fraction of manure drains from pig-breeding farms // 2628437
FIELD: agriculture.SUBSTANCE: method for utilizing the liquid fraction of manure drains from pig-breeding farms includes separating the manure, introducing a chemical reagent into the liquid manure fraction, and stirring the mixture. For the purpose of utilizing the liquid fraction of the manure drains from pig-breeding farms, reducing the concentration of organic and inorganic pollutants, the aqueous solution of sodium hypochlorite is introduced in the active chlorine concentration equal to 185 g/l, equivalent to the sum of the concentration of organic components. Thereinafter carbonic acid is added until the neutral acidity of the medium is achieved, and then the cleaned sewage is mixed with the river water at the ratio of 1:10 and discharged into a river basin.EFFECT: invention allows to process the liquid fraction of manure drains from a pig-breeding complex and to bring these drains to sanitary standards.2 cl, 2 tbl, 2 ex
ethod for extracting pectin substances from sugar beet production wastes // 2628435
FIELD: food industry.SUBSTANCE: method for extracting pectin substances includes washing the raw materials with water, grinding, sonication, hydrolysis and extraction, precipitation of pectin substances and their purification from the pectin-containing extract with ethyl alcohol. The sonication is carried out at the fixed frequency of 350 Hz, with the subsequent hydrolysis and extraction at the temperature of 55°C with the 1% solution of ammonium oxalate for 45-50 minutes. The obtained pectin-containing extract is purified and pectin substances are precipitated with ethyl alcohol with the addition of sodium chloride salt in the amount not exceeding 10 g per litre of the alcohol. Wherein the sonication is carried out for 20 minutes at the temperature of 40°C.EFFECT: invention allows to increase the yield of pectin and does not require the use of strong mineral acids as an extractant.3 ex

icrobial inoculants and fertilisers composition containing them // 2628411
FIELD: biotechnology.SUBSTANCE: microbial inoculant for increasing of plant growth, plant productivity and/or soil quality contains strains of two or more species of bacteria selected from Lactobacillus parafarraginis, Lactobacillus buchneri, Lactobacillus rapi and Lactobacillus zeae. The microbial inoculant contains at least one bacterial strain selected from Lactobacillus parafarraginis Lp18, Lactobacillus buchneri Lb23, Lactobacillus rapi Lr24 and Lactobacillus zeae Lz26. Application of inoculant as a fertiliser. The fertiliser composition contains a microbial inoculant. Application of the fertiliser composition. A method for increasing plant growth and/or productivity. A method to improve the quality of soil. Method for degraded soil or pasture recultivation.EFFECT: inventions make it possible to obtain fertilisers based on microorganisms that are effective in provision of nutrients for plant growth, and are environmentally safe.35 cl, 11 dwg, 5 tbl, 9 ex

Anthocyan colouring composition // 2628398
FIELD: chemistry.SUBSTANCE: colouring composition having a blue colour contains one or more anthocyans; metal ions of Fe (II), tannic acid as a stabiliser, in which the molar ratio of metal ions to anthocyanins is, at least, 0.5:1, and the molar ratio of stabiliser to anthocyanin is, at least, 0.5:1. The method for preparing a colouring composition having a blue colour comprises adjusting the pH of the anthocyan solution to a value between 3.5 and 8.0 before addition of Fe (II) metal ions and tannic acid as a stabiliser. Herewith the ratio of metal ions to anthocyanins is, at least, 0.5:1, and the molar ratio of stabiliser to anthocyanin is, at least, 0.5:1. The invention relates to the composition comprising a colouring composition, in which the pH is in the range of 3.5 to 8.0 and the composition is blue or green.EFFECT: improving the compound properties.13 cl, 1 dwg, 16 tbl, 9 ex

New plastifiing mixtures and plastisol compounds containing them // 2628395
FIELD: chemistry.SUBSTANCE: mixture contains a plasticiser based on benzoate ester as a primary plasticiser and a compatibilizing plasticizing component. The primary dibenzoate plasticiser is selected from the group: diethylene glycol dibenzoate, dipropylene glycol dibenzoate, 1,2-propylene glycol dibenzoate, and mixtures thereof. The compatibilizing plasticizing component is dioctyl succinate, 3-phenylpropyl benzoate or 1,2-propylene glycol dibenzoate in case, it is not used as a primary plasticiser.EFFECT: invention allows to produce plastisol compositions, phases of the liquid dispersant for the polymer, plasticizing mixtures having a low viscosity and good rheological characteristics.13 cl, 10 dwg, 9 tbl, 7 ex

Advanced coal gasification // 2628390
FIELD: oil and gas industry.SUBSTANCE: gasifier for producing synthesis gas comprises an upper gasification zone in a fluidized bed, which has inlets to allow the introduction of materials selected from the group consisting of carbon, fine carbon particles of greater than 75 micrometers and less than 10 mm in size, gas and steam in fluid communication through a venturi nozzle with the lower gasification zone in co-current which has inlets to allow the introduction of materials selected from the group consisting of coal, fine coal particles of less than 75 micrometers in size, gas and steam.EFFECT: increased efficiency of gasification, lower costs.16 cl, 1 dwg

Liquid purification method // 2628389
FIELD: chemistry.SUBSTANCE: liquid purification method consists in, at least, one automatically started liquid purifying cycle, during which the initial liquid is purified and the liquid purifying agent is rinsed with a liquid medium, followed by the renewal of the liquid purification. During this cycle, the initial liquid is supplied to the liquid purifying unit through the source liquid supply line, wherein the initial liquid is supplied to the liquid purifying agent through the pressure increasing means along the mixing line of the initial and drainage liquid. After the liquid purifying agent, the purified liquid enters the line of the purified liquid, and the drainage liquid is fed to the feed liquid in the recirculation line, and the resulting mixture enters the liquid purifying agent. After the predetermined time period, the liquid purifying process is interrupted for washing the liquid purifying agent with a liquid medium designed to remove contaminants generated on the inner surface of the liquid purifying agent. The liquid medium after the liquid purifying agent is discharged into the drain at high speed. During, at least, one liquid purifying cycle, prior to washing the liquid purifying agent with a liquid medium, the liquid purifying process is interrupted, at least, once for a short period of time sufficient to wash the liquid purifying agent with a mixture of drainage and initial liquid, at which the polarization layer of the contaminants is destroyed, formed on the inner surface of the liquid purifying agent, followed by the resumption of the liquid purifying process after each short washing of the liquid purifying agent. When washing the liquid purifying agent with a liquid medium, the duration of which exceeds the duration of, at least, one washing of the liquid purifying agent, at which the polarization layer of the contaminants is destroyed, a mixture of the initial and drainage liquid is used as a liquid medium.EFFECT: reducing the amount of the initial liquid used, reducing the amount of contaminants on the liquid purifying agent, prolonging the life of the liquid purifying agent.7 cl, 3 dwg

ultilayer composition, film and corresponding methods // 2628388
FIELD: physics.SUBSTANCE: multilayer structure contains a printing film and a pre-pressable film. The printing film comprises a printing layer and a carrier layer. In one embodiment, the print film further comprises an adhesive layer. In another embodiment, the print film further comprises an anti-adhesive patch. The printing layer comprises a polymeric material and a silicone additive. The material to be pre-pressed contains a polymeric material. The material to be pre-pressed may further comprise a functional material.EFFECT: environmentally friendly multi-layer structure provides improved printing properties.15 cl, 1 tbl, 7 dwg, 1 ex
Spherical moderated powder for automatic weapon and rifle cartridges // 2628385
FIELD: weapons and ammunition.SUBSTANCE: invention relates to spherical double-base moderated powder for small arm cartridges, namely automatic weapon and rifle cartridges of caliber from 5.45 to 12.7 mm. The powder consists of spheroidal granules with a phlegmatized surface layer and contains an energy base - nitrocellulose and nitroglycerin, a phlegmatizer-centralite No. 1, dibutyl phthalate and/or dioctyl phthalate, and/or diethyl hexyl phthalate and/or triethylene glycol dimethacrylate and/or oligoester acrylate, a solvent - ethyl acetate, stabilizator of chemical resistance - diphenylamine and water at a certain ratio of components. Wherein the thickness of the phlegmatized surface layer is 15.5-30% of the thickness of the combustible arch. The ratio of the diameter of the powder granule to the thickness of the combustible arch is from 1.0 to 2.05. The density of loading the cartridge with spherical moderated powder is from 0.85 to 1.15 g/cm3.EFFECT: increased speed of the bullet without increasing the maximum pressure of the powder gases.3 cl, 1 dwg, 4 tbl

ethod for nonchemical cleaning of saponite-containing water and compaction of saponite-containing sediment // 2628383
FIELD: chemistry.SUBSTANCE: in order to carry out the method, the contaminated saponite-containing water from the source of its formation (1) through a pulp pump station (3) and pulp line (4) is discharged to the offshore part (I) of the tailing dump (9) along the entire inner perimeter. A number of floating acoustic modules with emitters (14) are installed in the peripheral part (II) of the tailing dump (9) adjacent on the inner part to the k (I) and hydroacoustic signals of the sound and ultrasonic frequency range are generated and emitted, and continuous emission of signals of low sound frequency range is generated. The hydroacoustic signals of the sound and ultrasonic frequency ranges are formed with an acoustic pressure amplitude of at least 102 Pa at a distance of 1m from the hydroacoustic radiator, they impact on saponite-containing water for degassing, hydroacoustic coagulation of saponite-containing slime particles, and compaction of the saponite-containing sediment. The formation, amplification and emission of continuous hydroacoustic signals of a low sound frequency range are carried out in the frequency range from tens of Hz to units of kHz, with an acoustic pressure amplitude of at least 103 Pa at a distance of 1m from the hydroacoustic radiator and impact on the saponite-containing sediment. During the freeze-up period, an acoustically compacted saponite-containing sediment is raised to the ice surface and laid on the ice in the non-working offshore part of the tailing dump. In the summer period, the saponite-containing sediment is thawed with separation into a finally compacted saponite-containing sediment and clarified saponite-containing water with its subsequent use in the technological process.EFFECT: method provides a quick and qualitative separation of the saponite-containing tails of the concentrating plant into two phases, the compaction of the obtained saponite-containing sediment and the body of the waterproof dam, the clarification of large volumes of saponite-containing water, and the increased environmental safety of the tailing dump operation.8 dwg, 1 ex

Dry cellulose fibers and the process of making the same // 2628382
FIELD: chemistry.SUBSTANCE: dry cellulose fibers contain at least 50 wt % of fibers having a length of up to 350 mcm and a diameter in the range of 100-500 nm, where the fibers do not contain additives, are not derivatized and are redispersible in water. A film of dry cellulose fibers containing the described fibers is shown where the film is water dispersible. Also described is a process for producing a dry film of cellulose fibers, comprising preparing a liquid slurry from the above-described cellulosic fibers obtained by multi-step highly refined wood or plant fibers and retaining more than 90% of the fibers on the forming section of the papermaking machine in which the fibers do not contain additives and are not derivatized. The film can be converted into powders or flakes for transport, storage or subsequent use.EFFECT: creation of repeatedly water-dispersible fibers of fibrillated cellulose, obtained without the use of chemical additives and derivatization.23 cl, 3 dwg, 5 tbl, 5 ex

Acoustic polymeric intermediate layers, sustainable to defects formation // 2628380
FIELD: technological processes.SUBSTANCE: polymer layer for multi-layer glass panels comprises three polymer layers containing plasticized polyvinyl butyral with a molecular weight less than 140,000 Da in which the second polymer layer is positioned between the first polymer layer and the third polymer layer to form a polymer intermediate layer with two outer layers and one inner layer.EFFECT: creation of an intermediate layer for shatterproof glass, which provides glass with an increased level of sound insulation, reduced light transmission, and the absence of optical defects.10 cl, 3 tbl, 4 dwg
Phenol additive for electrodepositable coating composition containing cyclic guanidine // 2628379
FIELD: chemistry.SUBSTANCE: electrodepositable coating composition comprising a reaction product of an epoxy functional polymer and cyclic guanidine and a source of unreacted phenol are described. This electrodepositable coating composition exhibits a Coulomb consumption of less than 100 coulomb/gram, when applied to an electrically conductive substrate at a current density of ≤1.5 mA/cm2. A substrate and a method for coating a metal substrate are also described.EFFECT: electrodeposited coatings containing cyclic guanidine are produced, which are effectively and in sufficient quantity applied to the substrate.22 cl, 11 tbl, 1 dwg, 11 ex

Complex for industrial discharges and sewage water treatment // 2628376
FIELD: chemistry.SUBSTANCE: complex includes a housing with a capacity of (1), a transport-dewatering unit (5), three-type modular water purification devices (2, 3, 4), water supply (19) and discharge (10) devices. The capacity (1) of a triangular or trapezoidal section has an angle of sides inclination of 43-48° and is docked with the hulls of transport-dewatering units - horizontal (7) and inclined (8). Inside the case, modular water purification devices (2, 3, 4) of the same type are installed in pairs, separated by transverse partitions (6). The receiving section (9) is separated from modular "blinds" (2) devices by a partition (6) from the top to 2/3 of module height. Modular devices of thin-layer clarifiers (3) and modular devices for electrical water treatment (4) are separated by transverse partitions (6) from the bottom to 2/3 of modules height. The water discharge device (10) is separated from modular electrical processing devices (4) by a transverse partition (6) from the top. The transport devices (7) and (8) are pipes with slots in the sludge outlet vessel (1) and are docked at an angle of 8-13° with the screws (11) placed inside. The slot (14) of the transport-dewatering unit (5) is cut in the pipes from the partition separating the modular water treatment device (4) to the point of tank filling with water on an inclined pipe that has a tie sieve (15) on the upper end and a pan (16) with a discharge pipe (17) to discharge the sub-product into the container (1). The slot (14) is covered by a grid (18) made of plates installed at an angle of 45°. The water supply device has a flat bell (20), the water discharge device (10) has a pipe diameter that ensures flow rate of not more than 0.1 m/s in the complex.EFFECT: complex provides reliability, design simplification and reduction of equipment dimensions.1 dwg

icroencapsulated fire extinguishing agent and method of its obtaining // 2628375
FIELD: fire safety.SUBSTANCE: describes a microencapsulated fire extinguishing agent comprising, in each microcapsule, a polymeric shell and a core containing as carrier gas components having a boiling point of -155 to +10°C, a flame retardant and a combustion inhibitor in a weight ratio: a carrier gas of 5-50%, a flame retardant of 30-70%, a flame retardant of 1-25%. A method for the preparation of microcapsules is also described.EFFECT: microencapsulated fire extinguishing agent with high reliability and fire-extinguishing efficiency was obtained.19 cl, 1 tbl, 8 ex
ethod of coal preparation to obtain humates // 2628358
FIELD: agriculture.SUBSTANCE: method for coal preparation to obtain humates includes cleaning it from mechanical impurities and grinding. Coal is crushed to size less 2 mm, checked for the content of toxic metals, including lead, arsenic, cadmium, mercury, and if at least one of them is detected with concentrations exceeding the maximum concentration limit (MCL), the coal is introduced into a 10-20% aqueous solution of hydrochloric acid with a temperature of 80-95°C and kept stirred for 4-8 hours. Then, it is washed in pure fresh water with a temperature of 80-95°C, rechecked for toxic metals and if the concentration of at least one of the toxic metals does not fall below the MCL, the acid treatment and washing processes are repeated in said modes in order to reduce the content of all toxic metals below the MCL.EFFECT: invention allows to lower the content of toxic metals below the MCL, which are in the natural coal intended for the production of alkali metal humates from it, and thereby to ensure suitability of the product obtained for human consumption.2 cl, 2 ex
Stimulator of oil-bearing formation productivity // 2628355
FIELD: oil and gas industry.SUBSTANCE: stimulator of oil formation productivity serving as an additive to the process fluids contains, wt %: an inorganic salt or a mixture of salts of at least 70; nonionic or cationic surfactant with demulsifying and hydrophobizing properties, or a mixture of said surfactants of at least 1; acid is not less than 3; sodium gluconate is not less than 1.EFFECT: stimulation of oil and gas-bearing formation productivity by combining technological operations with gentle rock processing allowing to increase the phase permeability, hydrophobicize the treated surface, remove capillary-bound water from the pores of the formation, remove sediments and prevent their further formation.3 cl, 4 tbl

Gypsum products with high-efficient heat-absorbing additives // 2628347
FIELD: construction.SUBSTANCE: gypsum article comprises a cured gypsum core layer, at least partially covered with at least one facing sheet, at least one of the liner sheets comprising paper and aluminium trihydrate, the paper being obtained from at least a pulp and aluminium trihydrate, and wherein the aluminium trihydrate is present in an amount of from about 5% to about 40 wt % relative to the pulp in a dry state.EFFECT: increasing the stability of gypsum products to high temperatures.9 cl, 12 dwg, 4 tbl

ethod for complex hydrogen thermo-barochemical processing of production formation // 2628342
FIELD: oil and gas industry.SUBSTANCE: method of complex hydrogen thermo-barochemical treatment of the bottomhole zone of a production formation includes separate and sequential delivery to the bottomhole through the tubing of hydro-reactive compositions based on aluminium hydride sodium composite and combustible-oxidizing compositions based on complex salts. The injection of the first mixture of combustible-oxidizing and hydro-reactive compounds with a density of 1.35-1.4 g/cm3 with filling of production string volume from bottomhole to lower perforations level. On top of the first mixture an aggregate-stable nanosuspension of hydro-reactive composition of density 1.23-1.25 g/cm3 with a content of 5-50% of the dispersed phase of aluminium hydride sodium composite in the dispersion medium of diesel fuel and organic solvent with quantitative content of the liquid phase components taken in proportional ratio providing the equality of the densities of the liquid and solid phases of nanosuspension which is injected at the predetermined value of formation porosity exceeding in the volume of the production string of the perforation zone interval followed by setting of aggregate-stable nanosuspension of hydroreactive composition directly to the bottomhole zone of the production formation. The second mixture of combustible-oxidizing and hydro-reactive compounds with a density of 1.6-1.8 g/cm3 in volume sufficient to effectively react with the first mixture of the fuel-oxidizing and hydro-reactive compounds.EFFECT: increase processing efficiency in order to increase the permeability of the bottomhole formation zone, reduce the skin factor and increase the performance of well, possibility to use it for hard-to-recover oil and gas reserves.2 cl, 3 dwg
icroencapsulated bacterial consortium for gluten degradation in fermented dough and method for obtaining said fermented dough // 2628314
FIELD: food industry.SUBSTANCE: microencapsulated bacterial consortium for gluten degradation contains Lactobacillus plantarum ATCC 8014, Lactobacillus sanfranciscensis ATCC 27652 and Lactobacillus brevis ATCC 14869, encapsulating agents, prebiotics selected from the group including polydextrose, inulin and agave syrup, and trehalose in combination with a proteolytic enzyme of bacterial origin and a proteolytic enzyme of fungal origin commonly used for baking. The method for obtaining a consortium for gluten degradation comprises the stages of separately reacting each strain of lactic acid bacteria, separately cultivating each activated strain in a liquid culture medium until each strain reaches a predetermined concentration, removing for each strain the culture medium excess for concentrating the microorganisms, preferably by centrifugation, with obtaining granules, separately resuspending the granules for each strain in a suspension of the saline solution and adjusting to a predetermined volume, mixing the required amounts of each strain and adjusting to a final volume, dissolving the encapsulating agents in water at suitable proportions of dissolved dry substances from 20 to 30%, adding prebiotic and trehalose, inoculating the mixture of the three strains of lactic acid bacteria with obtaining approximately 1010 CFU of said mixture of three strains of lactic acid bacteria per gram of the encapsulated powdery substance, and spray drying with the inlet temperature of 110 to 160°C and the outlet temperature of 60 to 80°C, at a feed rate of 20 to 50 ml/min. Invention also relates to fermented dough, the method for its obtaining, and sweet baked products obtained from the fermented gluten-free dough.EFFECT: group of inventions allows to obtain a consortium which is stable and quickly activated.17 cl, 4 tbl, 6 ex

Single-chemical nucleic acid molecules for gene expression control // 2628311
FIELD: biotechnology.SUBSTANCE: invention relates to biochemistry, in particular to a single-stranded nucleic acid molecule that inhibits target gene expression. The said molecule in the order from the 5'-end to the 3'-end contains the 5'-end portion Xc, the linker portion Lx, the inner portion Z, the linker portion Ly and the 3'-end portion Yc. At that, the inner region Z consists of the inner 5'-end portion X that is complementary to the 5'-end portion Xc and the inner 3'-end portion Y that is complementary to the 3'-end portion Yc. At that, Z consists of 19-30 bases and contains a sequence that suppresses the target gene expression. Z-(Xc+Yc) from 0 to 4 bases, Xc from 1 to 11 bases and Yc from 1 to 11 bases. This invention also discloses a method, application and composition for target gene expression inhibition, method, use and pharmaceutical composition for treatment of a disease caused by an increase in target gene expression using the above-mentioned nucleic acid molecule and the use of such molecule to induce RNA interference.EFFECT: invention allows application of a single-stranded nucleic acid molecule for patients treatment, since it does not cause a side effect in the form of interferon induction.32 cl, 32 dwg, 7 tbl, 25 ex

ethod for recombinant polypeptide production // 2628310
FIELD: pharmacology.SUBSTANCE: method for antibody production, a method for production of a pharmaceutical preparation containing an antibody obtained by this method, a nucleic acid molecule, application of a vector containing such nucleic acid molecule, and application of a cell where the said nucleic acid molecule or vector is artificially introduced in the method for antibody production. This method for antibody production involves culturing a cell that expresses an antibody-enhancing sequence (APES) that has been artificially inserted into a cell and into which an exogenous DNA encoding the desired antibody was introduced to produce the desired antibody, and wherein APES is a nucleic acid molecule containing a nucleotide sequence that can bind to DNA or mRNA of NfkBia gene derived from a human, mouse, rat, or hamster by base pairing, and can suppress expression of the NfkBia gene.EFFECT: invention allows production of an antibody at a high level with suppression of NfkBia expression.16 cl, 29 dwg, 8 ex
ethod for protecting internal reactor surfaces from saturation with working medium components during chemical-thermal treatment of parts // 2628309
FIELD: chemistry.SUBSTANCE: method for protecting the internal reactor surfaces from saturation with the working medium components during the chemical-thermal treatment of parts involves the formation of a protective coating on the inner reactor surfaces, chemically neutral to the working medium. Initially, during the formation of the protective coating, from 3 to 10 nominal coating cycles are carried out on the part to produce a coating on the internal reactor surfaces from the working agent used in the chemical-thermal treatment, after which an idle cycle of the reactor operation is carried out, in which an oxidizer is introduced into the reactor cavity to form an oxide layer on the surface of the produced coating. The idle cycle is repeated every 30-50 normal cycles of chemical-thermal treatment.EFFECT: improving the quality of the coating applied to the part by eliminating the transfer of working agent depositions from the internal reactor surfaces to the parts.1 cl

New fucosyltransferases and applications thereof // 2628307
FIELD: biotechnology.SUBSTANCE: bacterial host cell is provided comprising a sequence consisting of a polynucleotide encoding a polypeptide with alpha-1,2-fucosyltransferase activity (SEQ ID NO: 1) to produce 2'-fucosyllactose. Also methods for 2'-fucosyllactose production using the said polypeptide with alpha-1,2-fucosyltransferase activity, a donor substrate containing a fucose residue and an acceptor substrate comprising or consisting of lactose.EFFECT: group of inventions allows to facilitate production of fucosylated oligosaccharides of human milk, making it more efficient and economical due to the possibility of lactose application as a substrate for alpha-1,2-fucosyltransferase.9 cl, 13 dwg, 3 tbl, 1 ex

Human antibodies to clostridium difficile toxins // 2628305
FIELD: biotechnology.SUBSTANCE: completely human antibodies that bind either to toxin A, or to toxin B Clostridium difficile, or both to toxin A and toxin B. Formulations containing these antibodies and methods for their application are also described. The antibodies of the present invention are useful for neutralisation of toxins from C. difficile, thus providing agents for treatment of disease and symptoms associated with C. difficile infection, including an agent for treatment of diarrhea or pseudomembranous colitis caused by C. difficile. Antibodies may also limit the severity and/or duration of the underlying disease or limit the amount, duration and/or severity of disease relapse or exacerbation due to the presence of C. difficile.EFFECT: antibodies of this invention may also be suitable for infection diagnosis.34 cl, 5 dwg, 10 tbl, 11 ex
ethod of producing alkoxysilanes // 2628299
FIELD: chemistry.SUBSTANCE: one-step method of producing tri- and tetraalkoxysilanes is proposed, involving direct interaction of silicon with an appropriate aliphatic alcohol containing 1 to 4 carbon atoms, in the presence of a catalyst such as copper or copper chloride at a temperature of 200-300°C, which is carried out in the vibrating bed of milling bodies in the acceleration range of oscillations of 26.6 to 985.9 m/s2.EFFECT: method is chlorine-free process that meets modern environmental requirements, and ensures the production of the desired product in high yield and high conversion of the starting materials.8 cl, 7 ex

ethod and intermediate compounds for pregabaline production // 2628298
FIELD: pharmacology.SUBSTANCE: invention relates to a method for preparation of a compound of the formula and intermediates used to implement the method, as well as a method for pregabalin preparation.EFFECT: method can be implemented on a commercial scale using readily available, safe raw materials and reagents, and without the need for difficult separations.20 cl, 8 tbl, 41 ex

Phosphor-potassium-nitrogen-containing npk-fertiliser and method of producing granulated phosphor-potassium-nitrogen-containing npk-fertilisers // 2628292
FIELD: chemistry.SUBSTANCE: complex nitrogen-phosphate-potassium fertiliser (NPK) contains ammonium nitrate, anhydrous calcium sulfate, potassium dihydrogen phosphate. Mass fraction of total nitrogen from 13-15%, mass fraction of total phosphates in terms of P2O5 from 9-10%, the mass fraction of potassium in terms of K2O from 13-15%. The method of producing a complex NPK-fertiliser from a solid phosphate salt, which is a mixture of the fluorapatite Ca5(PO4)3F and dicalcium phosphate CaHPO4×nH2O, where n is from 0 to 2, and the content of fluorapatite Ca5(PO4)3<F from 27 to 99% includes: a step of decomposing the said solid phosphate salt with a sulfuric acid by a semi-dry method, a step of adding potassium sulfate as a source of potassium, ammonium nitrate as a source of nitrogen, a step of preparing the slink NPK, and granulating and drying step of the finished product.EFFECT: improving the properties of NPK-fertiliser, increasing the strength of granules, solving the problem associated with the plasticity of granular complex fertilisers, increasing the water solubility of phosphorus contained in the fertiliser, and improving the consumer properties of NPK-fertilisers.12 cl, 1 dwg, 3 tbl, 3 ex
ethod of manufacture of products from pseudo-alloys molybden-copper // 2628233
FIELD: metallurgy.SUBSTANCE: method includes preparing the molybdenum charge, pressing the preform, sintering the preform to form a porous framework, contacting the side of the resulting preform with copper taken in excess, impregnating the preform with copper, and cooling it. The impregnated workpiece is cooled from the impregnation temperature to the crystallization temperature of copper. In the impregnated workpiece, a temperature gradient is created directed toward the area of the excess copper location from the opposite side of the workpiece, to allow the blank to cool from the side opposite to that region of excess copper.EFFECT: increase in the relative density of products and the absence of anisotropy of physical properties.2 ex
ethod of producing titanium powder // 2628228
FIELD: metallurgy.SUBSTANCE: method involves loading sponge titanium into a retort, vacuuming and heating it in a vacuum, feeding hydrogen to the retort with hydrogenation of the sponge titanium while cooling the retort, extracting the hydrogenated sponge titanium from the retort, grinding it and sieving it into fractions, charging the crushed hydrogenated titanium powder in the retort, dehydrogenating it, cooling the retort and extracting the titanium powder. Hydrogen is fed into the retort at a speed of not more than 360 m3/hour per 1m2 of the retort section with the provision of an excess hydrogen pressure in the retort of not more than 44 kPa. The hydrogenated sponge titanium is ground in an argon atmosphere at an excess pressure of not more than 10-20 kPa, and the dehydrogenation is carried out by sealing the retort, evacuating it to a residual pressure of 0.01 kPa, heating and supplying argon at an overpressure of 10-30 kPa, wherein hydrogen released during dehydrogenation together with argon with a residual pressure of 0.01 kPa and a thermal aging is carried out for 3-5 hours.EFFECT: production of titanium powder of a given shape, fragmentation, needle type, with a reduced content of gas impurities such as hydrogen, nitrogen, chlorine and oxygen is ensured.2 cl

Hot-pressed thick-sheet steel, product moulded by stamping, and method of manufacturing products moulded by stamping // 2628184
FIELD: metallurgy.SUBSTANCE: steel contains, wt %: C: 0.15 to 0.5, Si: 0.2 to 3, Mn: 0.5 to 3, P: 0.05 or less (except 0), S: 0.05 or less (except 0), Al: 0.01 to 1, B: of 0.0002 to 0.01, N: 0.001 to 0.01%, Ti: in the amount equal to or greater than 3.4[N]0.01% and equal to or less than 3.4[N]0.1%, where [N] is the content (wt %) N, the rest are iron and unavoidable impurities. The average diameter of the equivalent circle of Ti-containing inclusions having an equivalent circle diameter of 30 nm or less among the Ti-containing inclusions contained in the steel sheet is 3 nm or more. The amount of Ti in the inclusions and the total amount of Ti in the steel satisfy the ratio: (the amount of Ti in the inclusions (wt %)-3.4[N])≥0.5×[(total amount of Ti (wt %))-3.4[N]], where [N] is the content (wt %) N in the steel. The share of ferrite in the metallographic microstructure is 30% or more.EFFECT: required balance between high strength and elasticity is provided.6 cl, 1 dwg, 16 tbl, 2 ex
Extraction of basic metals from sulfide ores and concentrates // 2628183
FIELD: chemistry.SUBSTANCE: process comprises the steps of mixing the ore-containing base metal with the ferric salts. Base metals are preferably copper, nickel and zinc. The mixture is then heated, water is added to form a slurry, mixed and the slurry is filtered.EFFECT: increasing the efficiency of extraction of the specified metals at processing of ores and concentrates with the low maintenance of sulfides.10 cl, 3 tbl, 3 ex
 
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